This paper focuses on the H∞ controller design for linear systems with time-varying delays and norm-bounded parameter perturbations in the system state and control/disturbance. On the existence of delayed/undelayed f...This paper focuses on the H∞ controller design for linear systems with time-varying delays and norm-bounded parameter perturbations in the system state and control/disturbance. On the existence of delayed/undelayed full state feedback controllers, we present a sufficient condition and give a design method in the form of Riccati equation. The controller can not only stabilize the time-delay system, but also make the H∞ norm of the closed-loop system be less than a given bound. This result practically generalizes the related results in current literature.展开更多
This paper introduces an optimized planning approach for integrating photovoltaic as distributed generation (PV-DG) into the radial distribution power systems, utilizing exhaustive load flow (ELF), loss sensitivity fa...This paper introduces an optimized planning approach for integrating photovoltaic as distributed generation (PV-DG) into the radial distribution power systems, utilizing exhaustive load flow (ELF), loss sensitivity factor (LSF), genetic algorithms (GA) methods, and numerical method based on LSF. The methodology aims to determine the optimal allocation and sizing of multiple PV-DG to minimize power loss through time series power flow analysis. An approach utilizing continuous sensitivity analysis is developed and inherently leverages power flow and loss equations to compute LSF of all buses in the system towards employing a dynamic PV-DG model for more accurate results. The algorithm uses a numerical grid search method to optimize PV-DG placement in a power distribution system, focusing on minimizing system losses. It combines iterative analysis, sensitivity assessment, and comprehensive visualization to identify and present the optimal PV-DG configurations. The present-ed algorithms are verified through co-simulation framework combining MATLAB and OpenDSS to carry out analysis for 12-bus radial distribution test system. The proposed numerical method is compared with other algorithms, such as ELF, LSF methods, and Genetic Algorithms (GA). Results show that the proposed numerical method performs well in comparison with LSF and ELF solutions.展开更多
There has been an increasing interest in integrating decision support systems (DSS) and expert systems (ES) to provide decision makers a more accessible, productive and domain-independent information and computing env...There has been an increasing interest in integrating decision support systems (DSS) and expert systems (ES) to provide decision makers a more accessible, productive and domain-independent information and computing environment. This paper is aimed at designing a multiple expert systems integrated decision support system (MESIDSS) to enhance decision makers' ability in more complex cases. The basic framework, management system of multiple ESs, and functions of MESIDSS are presented. The applications of MESIDSS in large-scale decision making processes are discussed from the following aspects of problem decomposing, dynamic combination of multiple ESs, link of multiple bases and decision coordinating. Finally, a summary and some ideas for the future are presented.展开更多
The integration of artificial intelligence into the development and production of mechatronic products offers a substantial opportunity to enhance efficiency, adaptability, and system performance. This paper examines ...The integration of artificial intelligence into the development and production of mechatronic products offers a substantial opportunity to enhance efficiency, adaptability, and system performance. This paper examines the utilization of reinforcement learning as a control strategy, with a particular focus on its deployment in pivotal stages of the product development lifecycle, specifically between system architecture and system integration and verification. A controller based on reinforcement learning was developed and evaluated in comparison to traditional proportional-integral controllers in dynamic and fault-prone environments. The results illustrate the superior adaptability, stability, and optimization potential of the reinforcement learning approach, particularly in addressing dynamic disturbances and ensuring robust performance. The study illustrates how reinforcement learning can facilitate the transition from conceptual design to implementation by automating optimization processes, enabling interface automation, and enhancing system-level testing. Based on the aforementioned findings, this paper presents future directions for research, which include the integration of domain-specific knowledge into the reinforcement learning process and the validation of this process in real-world environments. The results underscore the potential of artificial intelligence-driven methodologies to revolutionize the design and deployment of intelligent mechatronic systems.展开更多
The present study aimed to design, develop, operate and evaluate a tourism planning support system that can be used to decide on places to eat lunch and dinner, sightseeing spots to visit along the way, and routes for...The present study aimed to design, develop, operate and evaluate a tourism planning support system that can be used to decide on places to eat lunch and dinner, sightseeing spots to visit along the way, and routes for visiting these destinations. This system was developed by integrating a web geographic information system (Web-GIS) and a sightseeing plan creation system (an eatery search system and a sightseeing route creation system). Additionally, the system was operated for one month in Central Yokohama City of Kanagawa Prefecture in Japan, and the total number of users was 79. Based on the results of the web questionnaire survey, user evaluations were particularly high for the function of sightseeing spot selection and the function of display of sightseeing plan information, and also for the entire system. From the results of the access analysis of users’ log data, the total number of sessions in the system was 263, 67% used mobile devices, and smartphones were used most frequently. Therefore, it is evident that the system was used by different types of devices just as it was designed for, and that the system was used according to the purpose of the present study, which is to support the food tourism planning of users.展开更多
This paper deals with the design and development of the observational system of geo-electrical resistivity on the basis of the demands for exploring the temporal variations of electrical properties of Earth media in t...This paper deals with the design and development of the observational system of geo-electrical resistivity on the basis of the demands for exploring the temporal variations of electrical properties of Earth media in the fixed points of the networks, which would be associated with the earthquake preparation. The observation system is characterized by the high accuracy in measurement, long term stability in operation and high level of rejection to the environmental interference. It consists of three main parts, configuration system measurement system, the calibration and inspection system.展开更多
The attitude tracking control problem for a satellite with parameter uncertainties and external disturbances is considered in this paper. For this class of multi-input multi-output uncertain nonlinear systems, a desig...The attitude tracking control problem for a satellite with parameter uncertainties and external disturbances is considered in this paper. For this class of multi-input multi-output uncertain nonlinear systems, a design method of robust output tracking controllers is proposed based on the upper-bounds of the uncertainties. Using the input/output feedback linearization approach and Lyapunov method, a control law is designed, which guarantees that the system output exponentially tracks the given desired output. The proposed controller is easy to compute and complement. Simulation results show that, in the closed-loop system, precise attitude control is accomplished in spite of the uncertainties in the system.展开更多
To improve the reliability and accuracy of the global po- sitioning system （GPS）/micro electromechanical system （MEMS）- inertial navigation system （INS） integrated navigation system, this paper proposes two diff...To improve the reliability and accuracy of the global po- sitioning system （GPS）/micro electromechanical system （MEMS）- inertial navigation system （INS） integrated navigation system, this paper proposes two different methods. Based on wavelet threshold denoising and functional coefficient autoregressive （FAR） model- ing, a combined data processing method is presented for MEMS inertial sensor, and GPS attitude information is also introduced to improve the estimation accuracy of MEMS inertial sensor errors. Then the positioning accuracy during GPS signal short outage is enhanced. To improve the positioning accuracy when a GPS signal is blocked for long time and solve the problem of the tra- ditional adaptive neuro-fuzzy inference system （ANFIS） method with poor dynamic adaptation and large calculation amount, a self-constructive ANFIS （SCANFIS） combined with the extended Kalman filter （EKF） is proposed for MEMS-INS errors modeling and predicting. Experimental road test results validate the effi- ciency of the proposed methods.展开更多
Based on the information fusion theory, a kind of integrated navigation system integration for cruise missile is presented in this paper. Besides, the way with which the system is integrated and the related data fusio...Based on the information fusion theory, a kind of integrated navigation system integration for cruise missile is presented in this paper. Besides, the way with which the system is integrated and the related data fusion technique are discussed. Information-fusion-based hybrid navigation system integration can fully utilize information provided by all kinds of navigation sensor subsystem and can improve the precision of the system effectively. Simultaneously, the reconstructing ability ensures the system of great reliability.展开更多
Helicobacter pylori (H. pylori) is one of the most common pathogenic bacterial infections and is found in the stomachs of approximately half of the world’s population. It is the primary known cause of gast...Helicobacter pylori (H. pylori) is one of the most common pathogenic bacterial infections and is found in the stomachs of approximately half of the world’s population. It is the primary known cause of gastritis, gastroduodenal ulcer disease and gastric cancer. However, combined drug therapy as the general treatment in the clinic, the rise of antibiotic-resistant bacteria, adverse reactions and poor patient compliance are major obstacles to the eradication of H. pylori. Oral site-specific drug delivery systems that could increase the longevity of the treatment agent at the target site might improve the therapeutic effect and avoid side effects. Gastroretentive drug delivery systems potentially prolong the gastric retention time and controlled/sustained release of a drug, thereby increasing the concentration of the drug at the application site, potentially improving its bioavailability and reducing the necessary dosage. Recommended gastroretentive drug delivery systems for enhancing local drug delivery include floating systems, bioadhesive systems and expandable systems. In this review, we summarize the important physiological parameters of the gastrointestinal tract that affect the gastric residence time. We then focus on various aspects useful in the development of gastroretentive drug delivery systems, including current trends and the progress of novel forms, especially with respect to their application for the treatment of H. pylori infections.展开更多
Due to the extensive applicability in real life, the non-smooth system with random factors attracted much attention in past two decades. A lot of methods and techniques have been proposed to research these systems by ...Due to the extensive applicability in real life, the non-smooth system with random factors attracted much attention in past two decades. A lot of methods and techniques have been proposed to research these systems by scholars. In this paper, we will summarize some new research advance on the stochastic non-smooth systems. The existing results about the stochastic vibro-impact system, the stochastic friction system, and the stochastic hysteretic system are introduced respectively. Some conclusions and outlook are given at the end.展开更多
In this paper, two types of mathematical models are developed to describe the dynamics of large-scale nonlinear systems, which are composed of several interconnected nonlinear subsystems. Each subsystem can be describ...In this paper, two types of mathematical models are developed to describe the dynamics of large-scale nonlinear systems, which are composed of several interconnected nonlinear subsystems. Each subsystem can be described by an input-output nonlinear discrete-time mathematical model, with unknown, but constant or slowly time-varying parameters. Then, two recursive estimation methods are used to solve the parametric estimation problem for the considered class of the interconnected nonlinear systems. These methods are based on the recursive least squares techniques and the prediction error method. Convergence analysis is provided using the hyper-stability and positivity method and the differential equation approach. A numerical simulation example of the parametric estimation of a stochastic interconnected nonlinear hydraulic system is treated.展开更多
Water is the key medium to transport numerous constituents and to provide a platform for physiological processes to take place in the living organisms in general;it also participates actively in many of these processe...Water is the key medium to transport numerous constituents and to provide a platform for physiological processes to take place in the living organisms in general;it also participates actively in many of these processes. In humans, there are different vehicles to contain water and its constituents. Our objective is to find out whether there is an overall water-base circulation system in the human body by analyzing the updated findings of different research groups on the physiological functions of various seemingly isolated fluid systems. By 1963, there were five separate fluid systems discovered in mammalians: (i) The Primo Vasculature Fluid (PVF) with protein precursors and micro cells held in the Primo Vasculature System (PVS). (ii) Blood with its constituents held in the cardio vasculature. (iii) Extracranial interstitial fluid (ISF) whose vehicle had a very irregular structure—the interstitium all over the body. (iv) The cerebrospinal fluid had been considered to be within the brain ventricles and spinal canal. (v) The extra-cranial lymphatic system which drained ISF, and had been known to join the subclavian vein. Fluid (i) was first reported in 1963 and fluids (ii) to (v) have been known for many decades, but the failure to detect a lymphatic system inside the skull has also been a mystery for many decades. The intra-cranial ISF (which we name as BISF) has drawn little attention, apart from discussing the mechanism of the blood-brain-barrier. During the past decade, there has been direct evidence indicating that CSF and BISF are actually mixed. After that, the intracranial lymphatic system was discovered and confirmed in animal models only slightly over one year back, and we called such fluid as glymphatic-fluid. After reviewing the stated “classical” five fluid systems together with the new findings in Sections 2 - 7, we propose, for the first time, that the PVF, the blood, ISF, a mixture of CSF-BISF, and a mixture of glymphatic-fluid and lymph form an integrative circulation system in water base in the human and other mammalian bodies, as schematically represented in the last section. In this paper, we point out the positive correlation of chronic neuro degenerative diseases such as Alzheimer’s disease, Parkinson’s diseases and the insufficient brain wastes clearance by the glymphatic system. We also discuss the role played by the venous vessels as part of such clearance in upright posture. Moreover, simple non-invasive maneuver techniques are introduced here, as one example of enhancement of glymphatic fluid flow out of the skull to join the lymphatic system. A series of questions are raised in Section 8, the answers to which would help us to understand the transition from physio- to pathological states in the development of many diseases. Detailed analysis of this paper leads us to consider that research in understanding this integrative circulation system is only at the infancy stage, and fluid dynamics investigation seems to be the plausible modality of approach in the near future.展开更多
The problem of robust stabilization for nonlinear systems with partially known uncertainties is considered in this paper. The required information about uncertainties in the system is merely that the uncertainties are...The problem of robust stabilization for nonlinear systems with partially known uncertainties is considered in this paper. The required information about uncertainties in the system is merely that the uncertainties are bounded, but the upper bounds are incompletely known. This paper can be viewed as an extension of the work in reference [1]. To compensate the uncertainties, an adaptive robust controller based on Lyapunov method is proposed and the design algorithm is also suggested. Compared with some previous controllers which can only ensure ultimate uniform boundedness of the systems, the controller given in the paper can make sure that the obtained closed-loop system is asymptotically stable in the large. Simulations show that the method presented is available and effective.展开更多
Based on the interpersonal function in Halliday’s systemic functional grammar,"Miranda Warnings",the typical English Police Caution,is analyzed from the aspects of Mood system,Modality system and Appraisal ...Based on the interpersonal function in Halliday’s systemic functional grammar,"Miranda Warnings",the typical English Police Caution,is analyzed from the aspects of Mood system,Modality system and Appraisal system,with the aim of exploring its interpersonal meanings.Results show that:first,the declarative mood and interrogative mood used in the police caution protect the legitimate rights of the interrogated;second,the widely use of Low value modal verbs demonstrates a more humane and democratic legislation principle;and third,the absence of Affect resources and the frequent application of Capacity resources narrow the interpersonal distance between policeman and the interrogated,reflecting the transformation in policeman’s interrogation practices.展开更多
Adaptive H∞ synchronization of chaotic systems via linear and nonlinear feedback control is investigated. The chaotic systems are redesigned by using the generalized Hamiltonian systems and observer approach. Based o...Adaptive H∞ synchronization of chaotic systems via linear and nonlinear feedback control is investigated. The chaotic systems are redesigned by using the generalized Hamiltonian systems and observer approach. Based on Lya-punov＇s stability theory, linear and nonlinear feedback control of adaptive H∞ synchronization is established in order to not only guarantee stable synchronization of both master and slave systems but also reduce the effect of external disturbance on an Hoe-norm constraint. Adaptive H∞ synchronization of chaotic systems via three kinds of control is investigated with applications to Lorenz and Chen systems. Numerical simulations are also given to identify the effectiveness of the theoretical analysis.展开更多
A simple criterion for delay-independent stability of large-scale linear time-varying systems is deduced by employing a type of Lyapunov function. The notable features of the results in this paper are its simplicity a...A simple criterion for delay-independent stability of large-scale linear time-varying systems is deduced by employing a type of Lyapunov function. The notable features of the results in this paper are its simplicity and efficiency in testing the stability large-scale linear time-varying systems. Some illustrative examples are given to demonstrate the advantages of the obtained results over those in literature.展开更多
基金This project was supported by the National Natural Science Foundation of China (No. 69974022).
文摘This paper focuses on the H∞ controller design for linear systems with time-varying delays and norm-bounded parameter perturbations in the system state and control/disturbance. On the existence of delayed/undelayed full state feedback controllers, we present a sufficient condition and give a design method in the form of Riccati equation. The controller can not only stabilize the time-delay system, but also make the H∞ norm of the closed-loop system be less than a given bound. This result practically generalizes the related results in current literature.
文摘This paper introduces an optimized planning approach for integrating photovoltaic as distributed generation (PV-DG) into the radial distribution power systems, utilizing exhaustive load flow (ELF), loss sensitivity factor (LSF), genetic algorithms (GA) methods, and numerical method based on LSF. The methodology aims to determine the optimal allocation and sizing of multiple PV-DG to minimize power loss through time series power flow analysis. An approach utilizing continuous sensitivity analysis is developed and inherently leverages power flow and loss equations to compute LSF of all buses in the system towards employing a dynamic PV-DG model for more accurate results. The algorithm uses a numerical grid search method to optimize PV-DG placement in a power distribution system, focusing on minimizing system losses. It combines iterative analysis, sensitivity assessment, and comprehensive visualization to identify and present the optimal PV-DG configurations. The present-ed algorithms are verified through co-simulation framework combining MATLAB and OpenDSS to carry out analysis for 12-bus radial distribution test system. The proposed numerical method is compared with other algorithms, such as ELF, LSF methods, and Genetic Algorithms (GA). Results show that the proposed numerical method performs well in comparison with LSF and ELF solutions.
文摘There has been an increasing interest in integrating decision support systems (DSS) and expert systems (ES) to provide decision makers a more accessible, productive and domain-independent information and computing environment. This paper is aimed at designing a multiple expert systems integrated decision support system (MESIDSS) to enhance decision makers' ability in more complex cases. The basic framework, management system of multiple ESs, and functions of MESIDSS are presented. The applications of MESIDSS in large-scale decision making processes are discussed from the following aspects of problem decomposing, dynamic combination of multiple ESs, link of multiple bases and decision coordinating. Finally, a summary and some ideas for the future are presented.
文摘The integration of artificial intelligence into the development and production of mechatronic products offers a substantial opportunity to enhance efficiency, adaptability, and system performance. This paper examines the utilization of reinforcement learning as a control strategy, with a particular focus on its deployment in pivotal stages of the product development lifecycle, specifically between system architecture and system integration and verification. A controller based on reinforcement learning was developed and evaluated in comparison to traditional proportional-integral controllers in dynamic and fault-prone environments. The results illustrate the superior adaptability, stability, and optimization potential of the reinforcement learning approach, particularly in addressing dynamic disturbances and ensuring robust performance. The study illustrates how reinforcement learning can facilitate the transition from conceptual design to implementation by automating optimization processes, enabling interface automation, and enhancing system-level testing. Based on the aforementioned findings, this paper presents future directions for research, which include the integration of domain-specific knowledge into the reinforcement learning process and the validation of this process in real-world environments. The results underscore the potential of artificial intelligence-driven methodologies to revolutionize the design and deployment of intelligent mechatronic systems.
文摘The present study aimed to design, develop, operate and evaluate a tourism planning support system that can be used to decide on places to eat lunch and dinner, sightseeing spots to visit along the way, and routes for visiting these destinations. This system was developed by integrating a web geographic information system (Web-GIS) and a sightseeing plan creation system (an eatery search system and a sightseeing route creation system). Additionally, the system was operated for one month in Central Yokohama City of Kanagawa Prefecture in Japan, and the total number of users was 79. Based on the results of the web questionnaire survey, user evaluations were particularly high for the function of sightseeing spot selection and the function of display of sightseeing plan information, and also for the entire system. From the results of the access analysis of users’ log data, the total number of sessions in the system was 263, 67% used mobile devices, and smartphones were used most frequently. Therefore, it is evident that the system was used by different types of devices just as it was designed for, and that the system was used according to the purpose of the present study, which is to support the food tourism planning of users.
文摘This paper deals with the design and development of the observational system of geo-electrical resistivity on the basis of the demands for exploring the temporal variations of electrical properties of Earth media in the fixed points of the networks, which would be associated with the earthquake preparation. The observation system is characterized by the high accuracy in measurement, long term stability in operation and high level of rejection to the environmental interference. It consists of three main parts, configuration system measurement system, the calibration and inspection system.
文摘The attitude tracking control problem for a satellite with parameter uncertainties and external disturbances is considered in this paper. For this class of multi-input multi-output uncertain nonlinear systems, a design method of robust output tracking controllers is proposed based on the upper-bounds of the uncertainties. Using the input/output feedback linearization approach and Lyapunov method, a control law is designed, which guarantees that the system output exponentially tracks the given desired output. The proposed controller is easy to compute and complement. Simulation results show that, in the closed-loop system, precise attitude control is accomplished in spite of the uncertainties in the system.
基金supported by the National Natural Science Foundation of China (60902055)
文摘To improve the reliability and accuracy of the global po- sitioning system （GPS）/micro electromechanical system （MEMS）- inertial navigation system （INS） integrated navigation system, this paper proposes two different methods. Based on wavelet threshold denoising and functional coefficient autoregressive （FAR） model- ing, a combined data processing method is presented for MEMS inertial sensor, and GPS attitude information is also introduced to improve the estimation accuracy of MEMS inertial sensor errors. Then the positioning accuracy during GPS signal short outage is enhanced. To improve the positioning accuracy when a GPS signal is blocked for long time and solve the problem of the tra- ditional adaptive neuro-fuzzy inference system （ANFIS） method with poor dynamic adaptation and large calculation amount, a self-constructive ANFIS （SCANFIS） combined with the extended Kalman filter （EKF） is proposed for MEMS-INS errors modeling and predicting. Experimental road test results validate the effi- ciency of the proposed methods.
文摘Based on the information fusion theory, a kind of integrated navigation system integration for cruise missile is presented in this paper. Besides, the way with which the system is integrated and the related data fusion technique are discussed. Information-fusion-based hybrid navigation system integration can fully utilize information provided by all kinds of navigation sensor subsystem and can improve the precision of the system effectively. Simultaneously, the reconstructing ability ensures the system of great reliability.
文摘Helicobacter pylori (H. pylori) is one of the most common pathogenic bacterial infections and is found in the stomachs of approximately half of the world’s population. It is the primary known cause of gastritis, gastroduodenal ulcer disease and gastric cancer. However, combined drug therapy as the general treatment in the clinic, the rise of antibiotic-resistant bacteria, adverse reactions and poor patient compliance are major obstacles to the eradication of H. pylori. Oral site-specific drug delivery systems that could increase the longevity of the treatment agent at the target site might improve the therapeutic effect and avoid side effects. Gastroretentive drug delivery systems potentially prolong the gastric retention time and controlled/sustained release of a drug, thereby increasing the concentration of the drug at the application site, potentially improving its bioavailability and reducing the necessary dosage. Recommended gastroretentive drug delivery systems for enhancing local drug delivery include floating systems, bioadhesive systems and expandable systems. In this review, we summarize the important physiological parameters of the gastrointestinal tract that affect the gastric residence time. We then focus on various aspects useful in the development of gastroretentive drug delivery systems, including current trends and the progress of novel forms, especially with respect to their application for the treatment of H. pylori infections.
基金Projected supported by the National Natural Science Foundation of China(Grant No.11472212)the Natural Science Basic Research Plan in Shaanxi Province,China(Grant No.2018JM1043)the Fundamental Research Fund for the Central Universities,China(Grant No.3102018ZY043)
文摘Due to the extensive applicability in real life, the non-smooth system with random factors attracted much attention in past two decades. A lot of methods and techniques have been proposed to research these systems by scholars. In this paper, we will summarize some new research advance on the stochastic non-smooth systems. The existing results about the stochastic vibro-impact system, the stochastic friction system, and the stochastic hysteretic system are introduced respectively. Some conclusions and outlook are given at the end.
基金supported by the Ministry of Higher Education and Scientific Research of Tunisia
文摘In this paper, two types of mathematical models are developed to describe the dynamics of large-scale nonlinear systems, which are composed of several interconnected nonlinear subsystems. Each subsystem can be described by an input-output nonlinear discrete-time mathematical model, with unknown, but constant or slowly time-varying parameters. Then, two recursive estimation methods are used to solve the parametric estimation problem for the considered class of the interconnected nonlinear systems. These methods are based on the recursive least squares techniques and the prediction error method. Convergence analysis is provided using the hyper-stability and positivity method and the differential equation approach. A numerical simulation example of the parametric estimation of a stochastic interconnected nonlinear hydraulic system is treated.
文摘Water is the key medium to transport numerous constituents and to provide a platform for physiological processes to take place in the living organisms in general;it also participates actively in many of these processes. In humans, there are different vehicles to contain water and its constituents. Our objective is to find out whether there is an overall water-base circulation system in the human body by analyzing the updated findings of different research groups on the physiological functions of various seemingly isolated fluid systems. By 1963, there were five separate fluid systems discovered in mammalians: (i) The Primo Vasculature Fluid (PVF) with protein precursors and micro cells held in the Primo Vasculature System (PVS). (ii) Blood with its constituents held in the cardio vasculature. (iii) Extracranial interstitial fluid (ISF) whose vehicle had a very irregular structure—the interstitium all over the body. (iv) The cerebrospinal fluid had been considered to be within the brain ventricles and spinal canal. (v) The extra-cranial lymphatic system which drained ISF, and had been known to join the subclavian vein. Fluid (i) was first reported in 1963 and fluids (ii) to (v) have been known for many decades, but the failure to detect a lymphatic system inside the skull has also been a mystery for many decades. The intra-cranial ISF (which we name as BISF) has drawn little attention, apart from discussing the mechanism of the blood-brain-barrier. During the past decade, there has been direct evidence indicating that CSF and BISF are actually mixed. After that, the intracranial lymphatic system was discovered and confirmed in animal models only slightly over one year back, and we called such fluid as glymphatic-fluid. After reviewing the stated “classical” five fluid systems together with the new findings in Sections 2 - 7, we propose, for the first time, that the PVF, the blood, ISF, a mixture of CSF-BISF, and a mixture of glymphatic-fluid and lymph form an integrative circulation system in water base in the human and other mammalian bodies, as schematically represented in the last section. In this paper, we point out the positive correlation of chronic neuro degenerative diseases such as Alzheimer’s disease, Parkinson’s diseases and the insufficient brain wastes clearance by the glymphatic system. We also discuss the role played by the venous vessels as part of such clearance in upright posture. Moreover, simple non-invasive maneuver techniques are introduced here, as one example of enhancement of glymphatic fluid flow out of the skull to join the lymphatic system. A series of questions are raised in Section 8, the answers to which would help us to understand the transition from physio- to pathological states in the development of many diseases. Detailed analysis of this paper leads us to consider that research in understanding this integrative circulation system is only at the infancy stage, and fluid dynamics investigation seems to be the plausible modality of approach in the near future.
文摘The problem of robust stabilization for nonlinear systems with partially known uncertainties is considered in this paper. The required information about uncertainties in the system is merely that the uncertainties are bounded, but the upper bounds are incompletely known. This paper can be viewed as an extension of the work in reference [1]. To compensate the uncertainties, an adaptive robust controller based on Lyapunov method is proposed and the design algorithm is also suggested. Compared with some previous controllers which can only ensure ultimate uniform boundedness of the systems, the controller given in the paper can make sure that the obtained closed-loop system is asymptotically stable in the large. Simulations show that the method presented is available and effective.
基金supported by National Natural Science Foundation of China(61403149,61573298)Natural Science Foundation of Fujian Province(2015J01261,2016J05165)Foundation of Huaqiao University(Z14Y0002)
基金supported by the Aerospace Science and Technology Innovation Foundation of China(CAST2014CH01)the Aeronautical Science Foundation of China(2015ZC560007)+1 种基金the Jiangxi Natural Science Foundation of China(20151BBE50026)National Natural Science Foundation of China(11462015)
文摘Based on the interpersonal function in Halliday’s systemic functional grammar,"Miranda Warnings",the typical English Police Caution,is analyzed from the aspects of Mood system,Modality system and Appraisal system,with the aim of exploring its interpersonal meanings.Results show that:first,the declarative mood and interrogative mood used in the police caution protect the legitimate rights of the interrogated;second,the widely use of Low value modal verbs demonstrates a more humane and democratic legislation principle;and third,the absence of Affect resources and the frequent application of Capacity resources narrow the interpersonal distance between policeman and the interrogated,reflecting the transformation in policeman’s interrogation practices.
文摘Adaptive H∞ synchronization of chaotic systems via linear and nonlinear feedback control is investigated. The chaotic systems are redesigned by using the generalized Hamiltonian systems and observer approach. Based on Lya-punov＇s stability theory, linear and nonlinear feedback control of adaptive H∞ synchronization is established in order to not only guarantee stable synchronization of both master and slave systems but also reduce the effect of external disturbance on an Hoe-norm constraint. Adaptive H∞ synchronization of chaotic systems via three kinds of control is investigated with applications to Lorenz and Chen systems. Numerical simulations are also given to identify the effectiveness of the theoretical analysis.
文摘A simple criterion for delay-independent stability of large-scale linear time-varying systems is deduced by employing a type of Lyapunov function. The notable features of the results in this paper are its simplicity and efficiency in testing the stability large-scale linear time-varying systems. Some illustrative examples are given to demonstrate the advantages of the obtained results over those in literature.
