Cultivation of the erythrocytic stages of Plasmodium parasites, specifically the most important and deadly for humans, Plasmodium falciparum, has required a lot of effort and time in order to develop a continuous in v...Cultivation of the erythrocytic stages of Plasmodium parasites, specifically the most important and deadly for humans, Plasmodium falciparum, has required a lot of effort and time in order to develop a continuous in vitro culture. Moreover, the development of methods to synchronize P. falciparum parasites (which grow asynchronously in vitro) has become an essential tool in research to study different immulogical, biochemical or physiological aspects of the parasite. We have compared two different synchronization methods, one based on differential permeability of the membrane of parasitized erythrocytes, and the other on the sedimentation behavior in gelatin solution. An optimized method has been established which allows for maintaining a healthy, highly synchronous culture for longer periods of time. Asexual erythrocytic stages of a complete P. falciparum cycle have been obtained, which is the starting point of the stage-specific assays of the activity of new antimalarial drugs.展开更多
With the increasing integration of renewable energy,microgrids are increasingly facing stability challenges,primarily due to the lack of inherent inertia in inverter-dominated systems,which is traditionally provided b...With the increasing integration of renewable energy,microgrids are increasingly facing stability challenges,primarily due to the lack of inherent inertia in inverter-dominated systems,which is traditionally provided by synchronous generators.To address this critical issue,Virtual Synchronous Generator(VSG)technology has emerged as a highly promising solution by emulating the inertia and damping characteristics of conventional synchronous generators.To enhance the operational efficiency of virtual synchronous generators(VSGs),this study employs smallsignal modeling analysis,root locus methods,and synchronous generator power-angle characteristic analysis to comprehensively evaluate how virtual inertia and damping coefficients affect frequency stability and power output during transient processes.Based on these analyses,an adaptive control strategy is proposed:increasing the virtual inertia when the rotor angular velocity undergoes rapid changes,while strengthening the damping coefficient when the speed deviation exceeds a certain threshold to suppress angular velocity oscillations.To validate the effectiveness of the proposed method,a grid-connected VSG simulation platform was developed inMATLAB/Simulink.Comparative simulations demonstrate that the proposed adaptive control strategy outperforms conventional VSGmethods by significantly reducing grid frequency deviations and shortening active power response time during active power command changes and load disturbances.This approach enhances microgrid stability and dynamic performance,confirming its viability for renewable-dominant power systems.Future work should focus on experimental validation and real-world parameter optimization,while further exploring the strategy’s effectiveness in improvingVSG low-voltage ride-through(LVRT)capability and power-sharing applications in multi-parallel configurations.展开更多
Permanent magnet synchronous motor(PMSM),known for their compact size and high-power density,is widely used in fields such as electric vehicles and servo drives.However,traditional PID control methods for PMSM cannot ...Permanent magnet synchronous motor(PMSM),known for their compact size and high-power density,is widely used in fields such as electric vehicles and servo drives.However,traditional PID control methods for PMSM cannot dynamically adjust parameters according to varying operating conditions.To address this issue,this paper proposes a PID control method based on a radial basis function(RBF)neural network,which adaptively tunes the PID controller parameters.First,an offline RBF neural network with optimal structural parameters is trained using the current and speed data of the PMSM,and then employed to construct the RBF-PID controller.During online training,the Jacobian information calculated via the RBF neural network is used to adaptively adjust the PID parameters.Simultaneously,the structural parameters of the RBF network are updated in reverse based on the error between the predicted and reference speed values.Finally,numerical simulations and experiments in the context of electric vehicle drive control show that the maximum speed errors of the SMC controller and the RBF-PID controller are 1.97 km/h and 0.17 km/h,respectively.Moreover,the RBF-PID controller outperforms both the SMC and traditional PID controllers in handling sudden speed changes.展开更多
BACKGROUND Cardiac myxoma is a benign neoplasm and one of the most common types of primary cardiac tumors.Synchronous cardiac myxoma and other malignancies are extremely rare,and only limited cases have been reported....BACKGROUND Cardiac myxoma is a benign neoplasm and one of the most common types of primary cardiac tumors.Synchronous cardiac myxoma and other malignancies are extremely rare,and only limited cases have been reported.CASE SUMMARY We describe a young patient with newly diagnosed locally advanced laryngeal cancer,with a synchronous cardiac tumor detected on staging scans.An echocar-diogram showed the typical appearance of myxoma in the left atrium.Early cardiac surgery was performed in view of its obstructive features and post cardiac surgery recovery was uneventful.The patient was scheduled for subsequent oncological treatment for the laryngeal cancer.However,due to rapid progression of the advanced laryngeal malignancy,he was placed on supportive care.CONCLUSION To our knowledge,this is the first reported case of synchronous cardiac myxoma with laryngeal malignancy.Individualized treatment strategy should be adopted to manage synchronous tumors in a multidisciplinary approach.The most life-threatening condition needs be treated first.Single resection,staged operations or simultaneous resection of both tumors have been reported with good outcomes.展开更多
This paper introduces a novel chattering-free terminal sliding mode control(SMC)strategy to address chaotic behavior in permanent magnet synchronous generators(PMSG)for offshore wind turbine systems.By integrating an ...This paper introduces a novel chattering-free terminal sliding mode control(SMC)strategy to address chaotic behavior in permanent magnet synchronous generators(PMSG)for offshore wind turbine systems.By integrating an adaptive exponential reaching law with a continuous barrier function,the proposed approach eliminates chattering and ensures robust performance under model uncertainties.The methodology combines adaptive SMC with dynamic switching to estimate and compensates for unknown uncertainties,providing smooth and stable control.Finally,the performance and effectiveness of the proposed approach are compared with those of a previous study.展开更多
This study presents an emergency control method for sub-synchronous oscillations in wind power gridconnected systems based on transfer learning,addressing the issue of insufficient generalization ability of traditiona...This study presents an emergency control method for sub-synchronous oscillations in wind power gridconnected systems based on transfer learning,addressing the issue of insufficient generalization ability of traditional methods in complex real-world scenarios.By combining deep reinforcement learning with a transfer learning framework,cross-scenario knowledge transfer is achieved,significantly enhancing the adaptability of the control strategy.First,a sub-synchronous oscillation emergency control model for the wind power grid integration system is constructed under fixed scenarios based on deep reinforcement learning.A reward evaluation system based on the active power oscillation pattern of the system is proposed,introducing penalty functions for the number of machine-shedding rounds and the number of machines shed.This avoids the economic losses and grid security risks caused by the excessive one-time shedding of wind turbines.Furthermore,transfer learning is introduced into model training to enhance the model’s generalization capability in dealing with complex scenarios of actual wind power grid integration systems.By introducing the Maximum Mean Discrepancy(MMD)algorithm to calculate the distribution differences between source data and target data,the online decision-making reliability of the emergency control model is improved.Finally,the effectiveness of the proposed emergency control method for multi-scenario sub-synchronous oscillation in wind power grid integration systems based on transfer learning is analyzed using the New England 39-bus system.展开更多
Laser-directed energy deposition(LDED)technology has demonstrated great potential for the rapid and integrated fabrication of nickel-based superalloy components.The plastic deformation-assisted method is crucial for a...Laser-directed energy deposition(LDED)technology has demonstrated great potential for the rapid and integrated fabrication of nickel-based superalloy components.The plastic deformation-assisted method is crucial for achieving grain refinement and microstructural homogeneity in LDED-fabricated superalloys.However,existing methods suffer from uniformity constraints owing to their high deformation resistance,which significantly limits their application in load-bearing components.To address these issues,a synchronous-hot-forging-assisted(SHFA)LDED additive manufacturing method was proposed,and its effects on the macroscopic morphology,microstructure,and mechanical properties of GH4169 nickel-based alloy specimens were systematically compared.The results demonstrated up to 30.1%average plastic deformation in hot-forging components while maintaining good surface flatness.The synergistic effect of dislocation accumulation and dynamic recrystallization during hot forging enables dramatic grain refinement,reducing the average grain size by 89.1%(from 168.5μm to 18.4μm)while weakening texture intensity from 15.31 to 2.15,ultimately promoting equiaxed grain formation.The pores of hot-forging components changed from fine round to flat,the porosity decreased from 0.264%to 0.089%,and the densification level was significantly improved.With the increase in the synchronous hot-forging force,the average ultimate tensile strength of hot-forging components can reach 1175.1 MPa,while the anisotropy difference is gradually weakened.The SHFA-LDED process not only achieves excellent grain refinement and microstructure homogenization but also enhances mechanical properties,providing a new technical path for the additive manufacturing of high-performance nickel-based superalloy components.展开更多
To explore the technical solution for independently-developed wireless synchronous control of locomotives based on 5G-R,this study investigates the service demands of such control and analyzes the insufficiency of the...To explore the technical solution for independently-developed wireless synchronous control of locomotives based on 5G-R,this study investigates the service demands of such control and analyzes the insufficiency of the existing communication system of China's heavy-haul railway.Giving full consideration of the high bandwidth,low delay,IP-based links,packet domain transmission,quality of service priority guarantee and other characteristics of the 5G-R network,an overall technical solution is proposed,focusing on the implementation of functions such as master-slave locomotive data transmission,controllable end-of-train data transmission,marshaling requests,and multi-driver calls.The findings contribute to enhancing the advancement of the independently-developed wireless synchronous control system of locomotives,ensuring its reliable operation in complex environments,providing valuable guidance for improving the safety and efficiency of heavy-haul railway transportation,and offering robust technical support for the modernization and intelligence development of heavy-haul railway.展开更多
To accomplish the reliability analyses of the correlation of multi-analytical objectives,an innovative framework of Dimensional Synchronous Modeling(DSM)and correlation analysis is developed based on the stepwise mode...To accomplish the reliability analyses of the correlation of multi-analytical objectives,an innovative framework of Dimensional Synchronous Modeling(DSM)and correlation analysis is developed based on the stepwise modeling strategy,cell array operation principle,and Copula theory.Under this framework,we propose a DSM-based Enhanced Kriging(DSMEK)algorithm to synchronously derive the modeling of multi-objective,and explore an adaptive Copula function approach to analyze the correlation among multiple objectives and to assess the synthetical reliability level.In the proposed DSMEK and adaptive Copula methods,the Kriging model is treated as the basis function of DSMEK model,the Multi-Objective Snake Optimizer(MOSO)algorithm is used to search the optimal values of hyperparameters of basis functions,the cell array operation principle is adopted to establish a whole model of multiple objectives,the goodness of fit is utilized to determine the forms of Copula functions,and the determined Copula functions are employed to perform the reliability analyses of the correlation of multi-analytical objectives.Furthermore,three examples,including multi-objective complex function approximation,aeroengine turbine bladeddisc multi-failure mode reliability analyses and aircraft landing gear system brake temperature reliability analyses,are performed to verify the effectiveness of the proposed methods,from the viewpoints of mathematics and engineering.The results show that the DSMEK and adaptive Copula approaches hold obvious advantages in terms of modeling features and simulation performance.The efforts of this work provide a useful way for the modeling of multi-analytical objectives and synthetical reliability analyses of complex structure/system with multi-output responses.展开更多
Permanent Magnet Synchronous Motors(PMSMs)are widely employed in high-performance drive applications due to their superior efficiency and dynamic capabilities.However,their control remains challenging owing to nonline...Permanent Magnet Synchronous Motors(PMSMs)are widely employed in high-performance drive applications due to their superior efficiency and dynamic capabilities.However,their control remains challenging owing to nonlinear dynamics,parameter variations,and unmeasurable external disturbances,particularly load torquefluctuations.This study proposes an enhanced Interconnection and Damp-ing Assignment Passivity-Based Control(IDA-PBC)scheme,formulated within the port-controlled Hamiltonian(PCH)framework,to address these limitations.A nonlinear disturbance observer is embedded to estimate and compensate,in real time,for lumped mis-matched disturbances arising from parameter uncertainties and external loads.Additionally,aflatness-based control strategy is employed to generate the desired current references within the nonlinear drive system,ensuring accurate tracking of time-varying speed commands.This integrated approach preserves the system’s energy-based structure,enabling systematic stability analysis while enhancing robustness.The proposed control architecture also maintains low complexity with a limited number of tunable parameters,facilitating practical implementation.Simulation and experimental results under various operating conditions demonstrate the effectiveness and robustness of the proposed method.Comparative analysis with conventional proportional-integral(PI)control and standard IDA-PBC strategies confirms its capability to handle disturbances and maintain dynamic performance.展开更多
Permanent magnet synchronous motor(PMSM)is widely used in alternating current servo systems as it provides high eficiency,high power density,and a wide speed regulation range.The servo system is placing higher demands...Permanent magnet synchronous motor(PMSM)is widely used in alternating current servo systems as it provides high eficiency,high power density,and a wide speed regulation range.The servo system is placing higher demands on its control performance.The model predictive control(MPC)algorithm is emerging as a potential high-performance motor control algorithm due to its capability of handling multiple-input and multipleoutput variables and imposed constraints.For the MPC used in the PMSM control process,there is a nonlinear disturbance caused by the change of electromagnetic parameters or load disturbance that may lead to a mismatch between the nominal model and the controlled object,which causes the prediction error and thus affects the dynamic stability of the control system.This paper proposes a data-driven MPC strategy in which the historical data in an appropriate range are utilized to eliminate the impact of parameter mismatch and further improve the control performance.The stability of the proposed algorithm is proved as the simulation demonstrates the feasibility.Compared with the classical MPC strategy,the superiority of the algorithm has also been verified.展开更多
Clock synchronization has important applications in multi-agent collaboration(such as drone light shows,intelligent transportation systems,and game AI),group decision-making,and emergency rescue operations.Synchroniza...Clock synchronization has important applications in multi-agent collaboration(such as drone light shows,intelligent transportation systems,and game AI),group decision-making,and emergency rescue operations.Synchronization method based on pulse-coupled oscillators(PCOs)provides an effective solution for clock synchronization in wireless networks.However,the existing clock synchronization algorithms in multi-agent ad hoc networks are difficult to meet the requirements of high precision and high stability of synchronization clock in group cooperation.Hence,this paper constructs a network model,named DAUNet(unsupervised neural network based on dual attention),to enhance clock synchronization accuracy in multi-agent wireless ad hoc networks.Specifically,we design an unsupervised distributed neural network framework as the backbone,building upon classical PCO-based synchronization methods.This framework resolves issues such as prolonged time synchronization message exchange between nodes,difficulties in centralized node coordination,and challenges in distributed training.Furthermore,we introduce a dual-attention mechanism as the core module of DAUNet.By integrating a Multi-Head Attention module and a Gated Attention module,the model significantly improves information extraction capabilities while reducing computational complexity,effectively mitigating synchronization inaccuracies and instability in multi-agent ad hoc networks.To evaluate the effectiveness of the proposed model,comparative experiments and ablation studies were conducted against classical methods and existing deep learning models.The research results show that,compared with the deep learning networks based on DASA and LSTM,DAUNet can reduce the mean normalized phase difference(NPD)by 1 to 2 orders of magnitude.Compared with the attention models based on additive attention and self-attention mechanisms,the performance of DAUNet has improved by more than ten times.This study demonstrates DAUNet’s potential in advancing multi-agent ad hoc networking technologies.展开更多
Software synchronous sampling is widely employed in periodic signal measurement, but measurement errors occur very commonly. This paper analyses the cause of the errors, deduces the mathematical model for the measure...Software synchronous sampling is widely employed in periodic signal measurement, but measurement errors occur very commonly. This paper analyses the cause of the errors, deduces the mathematical model for the measurement errors in measuring RMS voltage, RMS current and active power using the software synchronous sampling method. Some measures to reduce the errors are put forward by simulating.展开更多
To guarantee the safety of the high speed maglev train system, a novel model based on the winding function theory is proposed for the long-stator linear synchronous motor（LSM）, which is suitable for the real-time ca...To guarantee the safety of the high speed maglev train system, a novel model based on the winding function theory is proposed for the long-stator linear synchronous motor（LSM）, which is suitable for the real-time calculation of the running state. The accurate coupled mathematical models under different internal fault conditions of the LSM are derived based on the normal model. Then the fault currents and electromagnetic forces are simulated and calculated for the major potential internal faults of the LSM, such as the single-phase short circuit, the phase-phase short circuit and the single-phase open circuit. The characteristic curve between the electromagnetic force and the armature current of the LSM, which is compared with the results from the finite element method, proves the validation of the proposed method. The fault rule is determined and the proposed analytical model also shows its feasibility in the fast fault diagnosis through the comparison of the simulation results of currents and electromagnetic forces under different internal fault types and short circuit ratios.展开更多
AIM:To assess the clinicopathologic characteristics,risk factors,and prognosis for synchronous multiple early gastric cancer(SMGC).METHODS:A total of 146 patients with SMGC and1194 patients with single gastric cancer ...AIM:To assess the clinicopathologic characteristics,risk factors,and prognosis for synchronous multiple early gastric cancer(SMGC).METHODS:A total of 146 patients with SMGC and1194 patients with single gastric cancer who had undergone gastrectomy between 1989 and 2008 were retrospectively analyzed to determine their clinicopathologic characteristics and postoperative survival.Tumors were classified into groups on the basis of location and histology.Smoking habits were evaluated using the Brinkman index.Clinical and pathological factors were compared using either Fisher’s exact test or Pearson’sχ2test.Logistic regression analysis was performed to identify independent risk factors.Survival rate was calculated using the Kaplan-Meier method.RESULTS:SMGCs accounted for 10.9%of gastric cancer cases and occurred predominantly in elderly male patients with a family history of gastric cancer who were both smokers and drinkers.These tumors were typically macroscopically elevated and histologically differentiated.There were no significant differences between SMGC and single gastric cancer patients with respect to tumor location,tumor size,lymph node metastasis,the number of metastatic lymph nodes,venous invasion,or tumor stage(P=0.052,P=0.347,P=0.595,P=0.805,P=0.559,and P=0.408,respectively).Further,there was no significant difference in postoperative survival between the patient groups(P=0.200).Of the 146SMGC patients,a single patient had remnant cancer.CONCLUSION:A careful preoperative endoscopy is necessary for patients who are at high risk of SMGC,and minimally invasive treatment may be indicated in some cases.展开更多
AIM:To investigate the incidence of incidental gastrointestinal stromal tumor (GIST) and its etiopathogenesis.METHODS: From January 1, 2000 to December 31, 2007, 13 804 cases of gastrointestinal epithelial malignant t...AIM:To investigate the incidence of incidental gastrointestinal stromal tumor (GIST) and its etiopathogenesis.METHODS: From January 1, 2000 to December 31, 2007, 13 804 cases of gastrointestinal epithelial malignant tumor (EMT) and 521 cases of pancreatic adenocarcinoma (PAC) were successfully treated with surgery at the Department of General Surgery and the Department of Thoracic Surgery, West China Hospital, Sichuan University, China. The clinical and pathologic data of 311 cases of primary GIST, including 257 cases with clinical GIST and 54 cases of incidental GIST were analyzed.RESULTS: Of the 311 patients, 54 had incidental GIST, accounting for 17.4%. Of these tumors, 27 were found in 1.13% patients with esophageal squamous cell carcinoma (ESCC), 22 in 0.53% patients with gastric adenocarcinoma (GAC), 2 in 0.38% patients with PAC, 2 in 0.03% patients with colorectal adenocarcinoma, and 1 in one patient with GAC accompanying ESCC, respectively. Patients with incidental GIST presented symptoms indistinguishable from those with EMT. All incidental GIST lesions were small in size, and the majority had a low mitotic activity while only 1.9% (5/257) of clinical GIST lesions had a high risk.CONCLUSION: Incidental GIST may occur synchronously with other tumors and has a high prevalence in males. Surgery is its best treatment modality.展开更多
AIM： To identify patients with a high-risk of having a synchronous cancer among gastric cancer patients. METHODS： We retrospectively analyzed the prospective gastric cancer database at the National Cancer Center, Ko...AIM： To identify patients with a high-risk of having a synchronous cancer among gastric cancer patients. METHODS： We retrospectively analyzed the prospective gastric cancer database at the National Cancer Center, Korea from December 2000 to December 2004. The clinicopathological characteristics of patients with synchronous cancers and those of patients without synchronous cancers were compared. Multivariate analysis was performed to identify the risk factors for the presence of a synchronous cancer in gastric cancer patients. RESULTS： 111 of 3291 gastric cancer patients （3.4%） registered in the database had a synchronous cancer. Among these 111 patients, 109 had a single synchronous cancer and 2 patients had two synchronous cancers. The most common form of synchronous cancer was colorectal cancer （42 patients, 37.2%） followed by lung cancer （21 patients, 18.6%）. Multivariate analyses revealed that elderly patients with differentiated early gastric cancer have a higher probability of a synchronous cancer. CONCLUSION： Synchronous cancers in gastric cancer patients are not infrequent. The physicians should try to find synchronous cancers in gastric cancer patients, especially in the elderly with a differentiated early gastric展开更多
Laparoscopic resection of rectal cancer or gastric cancer has been advocated for the benefits of a reduced morbidity,a shorter treatment time,and similar outcomes.However,simultaneous laparoscopy-assisted low anterior...Laparoscopic resection of rectal cancer or gastric cancer has been advocated for the benefits of a reduced morbidity,a shorter treatment time,and similar outcomes.However,simultaneous laparoscopy-assisted low anterior resection and distal gastrectomy for synchronous carcinoma of rectum and stomach are rarely documented in literature.Endoscopic examination revealed a synchronous carcinoma of rectum and stomach in a 55-year-old male patient with rectal bleeding and epigastric discomfort.He underwent a simultaneous laparoscopy-assisted low anterior resection and distal gastrectomy with regional lymph nodes dissected.The operation time was 270 min and the estimated blood loss was 120 mL.The patient required parenteral analgesia for less than 24 h.Flatus was passed on postoperative day 3,and a solid diet was resumed on postoperative day 7.He was discharged on postoperative day 13.With the advances in laparoscopic technology and experience,simultaneous resection is an attractive alternative to a synchronous gastrointestinal cancer.展开更多
To investigate predictive markers for metachronous and synchronous gastric cancer (GC), which can develop after endoscopic submucosal dissection (ESD). METHODSA total of 352 patients underwent ESD for early GC at NTT ...To investigate predictive markers for metachronous and synchronous gastric cancer (GC), which can develop after endoscopic submucosal dissection (ESD). METHODSA total of 352 patients underwent ESD for early GC at NTT West Osaka Hospital between June 2006 and February 2016. Exclusion criteria were as follows: Remnant stomach, unknown Helicobacter pylori status, and endoscopic observation of the whole stomach outside our hospital. We analyzed data from 192 patients comprising 109 patients with solitary GC (Group A) and 83 with metachronous and synchronous GC (Group B). We retrospectively investigated the clinicopathological and endoscopic characteristics, and endoscopic risk score as predictive markers for GC. RESULTSThe median age of Group B [72 years (interquartile range 63-78)] was significantly higher than that of Group A [66 years (interquartile range 61-74), respectively, P = 0.0009]. The prevalence of intestinal metaplasia in Group B tended to be higher than that in Group A (57.8% vs 45.0%, P = 0.08). The prevalence of gastric xanthoma (GX) in Group B was significantly higher than that in Group A (54.2% vs 32.1%, P = 0.003). The atrophy score in Group B was significantly higher than that in Group A (P = 0.005). Multivariate analysis revealed that higher age and the presence of GX were independently related to metachronous and synchronous GC [OR = 1.04 (1.01-1.08), P = 0.02; and OR = 2.11 (1.14-3.99), P = 0.02, respectively]. CONCLUSIONThe presence of GX is a useful predictive marker for metachronous and synchronous GC.展开更多
文摘Cultivation of the erythrocytic stages of Plasmodium parasites, specifically the most important and deadly for humans, Plasmodium falciparum, has required a lot of effort and time in order to develop a continuous in vitro culture. Moreover, the development of methods to synchronize P. falciparum parasites (which grow asynchronously in vitro) has become an essential tool in research to study different immulogical, biochemical or physiological aspects of the parasite. We have compared two different synchronization methods, one based on differential permeability of the membrane of parasitized erythrocytes, and the other on the sedimentation behavior in gelatin solution. An optimized method has been established which allows for maintaining a healthy, highly synchronous culture for longer periods of time. Asexual erythrocytic stages of a complete P. falciparum cycle have been obtained, which is the starting point of the stage-specific assays of the activity of new antimalarial drugs.
基金financially supported by the Talent Initiation Fund of Wuxi University(550220008).
文摘With the increasing integration of renewable energy,microgrids are increasingly facing stability challenges,primarily due to the lack of inherent inertia in inverter-dominated systems,which is traditionally provided by synchronous generators.To address this critical issue,Virtual Synchronous Generator(VSG)technology has emerged as a highly promising solution by emulating the inertia and damping characteristics of conventional synchronous generators.To enhance the operational efficiency of virtual synchronous generators(VSGs),this study employs smallsignal modeling analysis,root locus methods,and synchronous generator power-angle characteristic analysis to comprehensively evaluate how virtual inertia and damping coefficients affect frequency stability and power output during transient processes.Based on these analyses,an adaptive control strategy is proposed:increasing the virtual inertia when the rotor angular velocity undergoes rapid changes,while strengthening the damping coefficient when the speed deviation exceeds a certain threshold to suppress angular velocity oscillations.To validate the effectiveness of the proposed method,a grid-connected VSG simulation platform was developed inMATLAB/Simulink.Comparative simulations demonstrate that the proposed adaptive control strategy outperforms conventional VSGmethods by significantly reducing grid frequency deviations and shortening active power response time during active power command changes and load disturbances.This approach enhances microgrid stability and dynamic performance,confirming its viability for renewable-dominant power systems.Future work should focus on experimental validation and real-world parameter optimization,while further exploring the strategy’s effectiveness in improvingVSG low-voltage ride-through(LVRT)capability and power-sharing applications in multi-parallel configurations.
文摘Permanent magnet synchronous motor(PMSM),known for their compact size and high-power density,is widely used in fields such as electric vehicles and servo drives.However,traditional PID control methods for PMSM cannot dynamically adjust parameters according to varying operating conditions.To address this issue,this paper proposes a PID control method based on a radial basis function(RBF)neural network,which adaptively tunes the PID controller parameters.First,an offline RBF neural network with optimal structural parameters is trained using the current and speed data of the PMSM,and then employed to construct the RBF-PID controller.During online training,the Jacobian information calculated via the RBF neural network is used to adaptively adjust the PID parameters.Simultaneously,the structural parameters of the RBF network are updated in reverse based on the error between the predicted and reference speed values.Finally,numerical simulations and experiments in the context of electric vehicle drive control show that the maximum speed errors of the SMC controller and the RBF-PID controller are 1.97 km/h and 0.17 km/h,respectively.Moreover,the RBF-PID controller outperforms both the SMC and traditional PID controllers in handling sudden speed changes.
文摘BACKGROUND Cardiac myxoma is a benign neoplasm and one of the most common types of primary cardiac tumors.Synchronous cardiac myxoma and other malignancies are extremely rare,and only limited cases have been reported.CASE SUMMARY We describe a young patient with newly diagnosed locally advanced laryngeal cancer,with a synchronous cardiac tumor detected on staging scans.An echocar-diogram showed the typical appearance of myxoma in the left atrium.Early cardiac surgery was performed in view of its obstructive features and post cardiac surgery recovery was uneventful.The patient was scheduled for subsequent oncological treatment for the laryngeal cancer.However,due to rapid progression of the advanced laryngeal malignancy,he was placed on supportive care.CONCLUSION To our knowledge,this is the first reported case of synchronous cardiac myxoma with laryngeal malignancy.Individualized treatment strategy should be adopted to manage synchronous tumors in a multidisciplinary approach.The most life-threatening condition needs be treated first.Single resection,staged operations or simultaneous resection of both tumors have been reported with good outcomes.
文摘This paper introduces a novel chattering-free terminal sliding mode control(SMC)strategy to address chaotic behavior in permanent magnet synchronous generators(PMSG)for offshore wind turbine systems.By integrating an adaptive exponential reaching law with a continuous barrier function,the proposed approach eliminates chattering and ensures robust performance under model uncertainties.The methodology combines adaptive SMC with dynamic switching to estimate and compensates for unknown uncertainties,providing smooth and stable control.Finally,the performance and effectiveness of the proposed approach are compared with those of a previous study.
基金funded by Sponsorship of Science and Technology Project of State Grid Xinjiang Electric Power Co.,Ltd.,grant number SGXJ0000TKJS2400168.
文摘This study presents an emergency control method for sub-synchronous oscillations in wind power gridconnected systems based on transfer learning,addressing the issue of insufficient generalization ability of traditional methods in complex real-world scenarios.By combining deep reinforcement learning with a transfer learning framework,cross-scenario knowledge transfer is achieved,significantly enhancing the adaptability of the control strategy.First,a sub-synchronous oscillation emergency control model for the wind power grid integration system is constructed under fixed scenarios based on deep reinforcement learning.A reward evaluation system based on the active power oscillation pattern of the system is proposed,introducing penalty functions for the number of machine-shedding rounds and the number of machines shed.This avoids the economic losses and grid security risks caused by the excessive one-time shedding of wind turbines.Furthermore,transfer learning is introduced into model training to enhance the model’s generalization capability in dealing with complex scenarios of actual wind power grid integration systems.By introducing the Maximum Mean Discrepancy(MMD)algorithm to calculate the distribution differences between source data and target data,the online decision-making reliability of the emergency control model is improved.Finally,the effectiveness of the proposed emergency control method for multi-scenario sub-synchronous oscillation in wind power grid integration systems based on transfer learning is analyzed using the New England 39-bus system.
基金supported by National Natural Science Foundation of China(Grant No.52375312)National Key Research and Development Program of China(Grant No.2023YFB4605900)+3 种基金Liaoning Province Science and Technology Plan Joint Program(Grant No.2023JH2/101700299)Open Research Fund of Key Laboratory of Precision Special Machining and Micromanufacturing Technology of Ministry of Education for Dalian University of Technology(Grant No.B202305)Shenzhen National Major Science and Technology Projects(Grant No.CJGJZD20240729113704006)Shenzhen Key Technology R&D Programs(Grant No.JSGG20210420091802007).
文摘Laser-directed energy deposition(LDED)technology has demonstrated great potential for the rapid and integrated fabrication of nickel-based superalloy components.The plastic deformation-assisted method is crucial for achieving grain refinement and microstructural homogeneity in LDED-fabricated superalloys.However,existing methods suffer from uniformity constraints owing to their high deformation resistance,which significantly limits their application in load-bearing components.To address these issues,a synchronous-hot-forging-assisted(SHFA)LDED additive manufacturing method was proposed,and its effects on the macroscopic morphology,microstructure,and mechanical properties of GH4169 nickel-based alloy specimens were systematically compared.The results demonstrated up to 30.1%average plastic deformation in hot-forging components while maintaining good surface flatness.The synergistic effect of dislocation accumulation and dynamic recrystallization during hot forging enables dramatic grain refinement,reducing the average grain size by 89.1%(from 168.5μm to 18.4μm)while weakening texture intensity from 15.31 to 2.15,ultimately promoting equiaxed grain formation.The pores of hot-forging components changed from fine round to flat,the porosity decreased from 0.264%to 0.089%,and the densification level was significantly improved.With the increase in the synchronous hot-forging force,the average ultimate tensile strength of hot-forging components can reach 1175.1 MPa,while the anisotropy difference is gradually weakened.The SHFA-LDED process not only achieves excellent grain refinement and microstructure homogenization but also enhances mechanical properties,providing a new technical path for the additive manufacturing of high-performance nickel-based superalloy components.
文摘To explore the technical solution for independently-developed wireless synchronous control of locomotives based on 5G-R,this study investigates the service demands of such control and analyzes the insufficiency of the existing communication system of China's heavy-haul railway.Giving full consideration of the high bandwidth,low delay,IP-based links,packet domain transmission,quality of service priority guarantee and other characteristics of the 5G-R network,an overall technical solution is proposed,focusing on the implementation of functions such as master-slave locomotive data transmission,controllable end-of-train data transmission,marshaling requests,and multi-driver calls.The findings contribute to enhancing the advancement of the independently-developed wireless synchronous control system of locomotives,ensuring its reliable operation in complex environments,providing valuable guidance for improving the safety and efficiency of heavy-haul railway transportation,and offering robust technical support for the modernization and intelligence development of heavy-haul railway.
基金co-supported by the National Natural Science Foundation of China(Nos.52405293,52375237)China Postdoctoral Science Foundation(No.2024M754219)Shaanxi Province Postdoctoral Research Project Funding,China。
文摘To accomplish the reliability analyses of the correlation of multi-analytical objectives,an innovative framework of Dimensional Synchronous Modeling(DSM)and correlation analysis is developed based on the stepwise modeling strategy,cell array operation principle,and Copula theory.Under this framework,we propose a DSM-based Enhanced Kriging(DSMEK)algorithm to synchronously derive the modeling of multi-objective,and explore an adaptive Copula function approach to analyze the correlation among multiple objectives and to assess the synthetical reliability level.In the proposed DSMEK and adaptive Copula methods,the Kriging model is treated as the basis function of DSMEK model,the Multi-Objective Snake Optimizer(MOSO)algorithm is used to search the optimal values of hyperparameters of basis functions,the cell array operation principle is adopted to establish a whole model of multiple objectives,the goodness of fit is utilized to determine the forms of Copula functions,and the determined Copula functions are employed to perform the reliability analyses of the correlation of multi-analytical objectives.Furthermore,three examples,including multi-objective complex function approximation,aeroengine turbine bladeddisc multi-failure mode reliability analyses and aircraft landing gear system brake temperature reliability analyses,are performed to verify the effectiveness of the proposed methods,from the viewpoints of mathematics and engineering.The results show that the DSMEK and adaptive Copula approaches hold obvious advantages in terms of modeling features and simulation performance.The efforts of this work provide a useful way for the modeling of multi-analytical objectives and synthetical reliability analyses of complex structure/system with multi-output responses.
基金supported in part by an International Research Partnership“Electrical Engineering-Thai French Research Center(EE-TFRC)”under the project framework of the Lorraine Universite´d’Excellence(LUE)in cooperation between Universite´de Lorraine(France)and King Mongkut’s University of Technology North Bangkok(year 2021-2024/2025-28)by the National Research Council of Thailand(NRCT)under Research Team Promotion Grant(Senior Research Scholar Program)under Grant No.N42A 680561by the NSRF via the Program Management Unit for Human Resources&Institutional Development,Research and Innovation under Research project Grant No.B41G680025.
文摘Permanent Magnet Synchronous Motors(PMSMs)are widely employed in high-performance drive applications due to their superior efficiency and dynamic capabilities.However,their control remains challenging owing to nonlinear dynamics,parameter variations,and unmeasurable external disturbances,particularly load torquefluctuations.This study proposes an enhanced Interconnection and Damp-ing Assignment Passivity-Based Control(IDA-PBC)scheme,formulated within the port-controlled Hamiltonian(PCH)framework,to address these limitations.A nonlinear disturbance observer is embedded to estimate and compensate,in real time,for lumped mis-matched disturbances arising from parameter uncertainties and external loads.Additionally,aflatness-based control strategy is employed to generate the desired current references within the nonlinear drive system,ensuring accurate tracking of time-varying speed commands.This integrated approach preserves the system’s energy-based structure,enabling systematic stability analysis while enhancing robustness.The proposed control architecture also maintains low complexity with a limited number of tunable parameters,facilitating practical implementation.Simulation and experimental results under various operating conditions demonstrate the effectiveness and robustness of the proposed method.Comparative analysis with conventional proportional-integral(PI)control and standard IDA-PBC strategies confirms its capability to handle disturbances and maintain dynamic performance.
文摘Permanent magnet synchronous motor(PMSM)is widely used in alternating current servo systems as it provides high eficiency,high power density,and a wide speed regulation range.The servo system is placing higher demands on its control performance.The model predictive control(MPC)algorithm is emerging as a potential high-performance motor control algorithm due to its capability of handling multiple-input and multipleoutput variables and imposed constraints.For the MPC used in the PMSM control process,there is a nonlinear disturbance caused by the change of electromagnetic parameters or load disturbance that may lead to a mismatch between the nominal model and the controlled object,which causes the prediction error and thus affects the dynamic stability of the control system.This paper proposes a data-driven MPC strategy in which the historical data in an appropriate range are utilized to eliminate the impact of parameter mismatch and further improve the control performance.The stability of the proposed algorithm is proved as the simulation demonstrates the feasibility.Compared with the classical MPC strategy,the superiority of the algorithm has also been verified.
文摘Clock synchronization has important applications in multi-agent collaboration(such as drone light shows,intelligent transportation systems,and game AI),group decision-making,and emergency rescue operations.Synchronization method based on pulse-coupled oscillators(PCOs)provides an effective solution for clock synchronization in wireless networks.However,the existing clock synchronization algorithms in multi-agent ad hoc networks are difficult to meet the requirements of high precision and high stability of synchronization clock in group cooperation.Hence,this paper constructs a network model,named DAUNet(unsupervised neural network based on dual attention),to enhance clock synchronization accuracy in multi-agent wireless ad hoc networks.Specifically,we design an unsupervised distributed neural network framework as the backbone,building upon classical PCO-based synchronization methods.This framework resolves issues such as prolonged time synchronization message exchange between nodes,difficulties in centralized node coordination,and challenges in distributed training.Furthermore,we introduce a dual-attention mechanism as the core module of DAUNet.By integrating a Multi-Head Attention module and a Gated Attention module,the model significantly improves information extraction capabilities while reducing computational complexity,effectively mitigating synchronization inaccuracies and instability in multi-agent ad hoc networks.To evaluate the effectiveness of the proposed model,comparative experiments and ablation studies were conducted against classical methods and existing deep learning models.The research results show that,compared with the deep learning networks based on DASA and LSTM,DAUNet can reduce the mean normalized phase difference(NPD)by 1 to 2 orders of magnitude.Compared with the attention models based on additive attention and self-attention mechanisms,the performance of DAUNet has improved by more than ten times.This study demonstrates DAUNet’s potential in advancing multi-agent ad hoc networking technologies.
文摘Software synchronous sampling is widely employed in periodic signal measurement, but measurement errors occur very commonly. This paper analyses the cause of the errors, deduces the mathematical model for the measurement errors in measuring RMS voltage, RMS current and active power using the software synchronous sampling method. Some measures to reduce the errors are put forward by simulating.
文摘To guarantee the safety of the high speed maglev train system, a novel model based on the winding function theory is proposed for the long-stator linear synchronous motor（LSM）, which is suitable for the real-time calculation of the running state. The accurate coupled mathematical models under different internal fault conditions of the LSM are derived based on the normal model. Then the fault currents and electromagnetic forces are simulated and calculated for the major potential internal faults of the LSM, such as the single-phase short circuit, the phase-phase short circuit and the single-phase open circuit. The characteristic curve between the electromagnetic force and the armature current of the LSM, which is compared with the results from the finite element method, proves the validation of the proposed method. The fault rule is determined and the proposed analytical model also shows its feasibility in the fast fault diagnosis through the comparison of the simulation results of currents and electromagnetic forces under different internal fault types and short circuit ratios.
文摘AIM:To assess the clinicopathologic characteristics,risk factors,and prognosis for synchronous multiple early gastric cancer(SMGC).METHODS:A total of 146 patients with SMGC and1194 patients with single gastric cancer who had undergone gastrectomy between 1989 and 2008 were retrospectively analyzed to determine their clinicopathologic characteristics and postoperative survival.Tumors were classified into groups on the basis of location and histology.Smoking habits were evaluated using the Brinkman index.Clinical and pathological factors were compared using either Fisher’s exact test or Pearson’sχ2test.Logistic regression analysis was performed to identify independent risk factors.Survival rate was calculated using the Kaplan-Meier method.RESULTS:SMGCs accounted for 10.9%of gastric cancer cases and occurred predominantly in elderly male patients with a family history of gastric cancer who were both smokers and drinkers.These tumors were typically macroscopically elevated and histologically differentiated.There were no significant differences between SMGC and single gastric cancer patients with respect to tumor location,tumor size,lymph node metastasis,the number of metastatic lymph nodes,venous invasion,or tumor stage(P=0.052,P=0.347,P=0.595,P=0.805,P=0.559,and P=0.408,respectively).Further,there was no significant difference in postoperative survival between the patient groups(P=0.200).Of the 146SMGC patients,a single patient had remnant cancer.CONCLUSION:A careful preoperative endoscopy is necessary for patients who are at high risk of SMGC,and minimally invasive treatment may be indicated in some cases.
文摘AIM:To investigate the incidence of incidental gastrointestinal stromal tumor (GIST) and its etiopathogenesis.METHODS: From January 1, 2000 to December 31, 2007, 13 804 cases of gastrointestinal epithelial malignant tumor (EMT) and 521 cases of pancreatic adenocarcinoma (PAC) were successfully treated with surgery at the Department of General Surgery and the Department of Thoracic Surgery, West China Hospital, Sichuan University, China. The clinical and pathologic data of 311 cases of primary GIST, including 257 cases with clinical GIST and 54 cases of incidental GIST were analyzed.RESULTS: Of the 311 patients, 54 had incidental GIST, accounting for 17.4%. Of these tumors, 27 were found in 1.13% patients with esophageal squamous cell carcinoma (ESCC), 22 in 0.53% patients with gastric adenocarcinoma (GAC), 2 in 0.38% patients with PAC, 2 in 0.03% patients with colorectal adenocarcinoma, and 1 in one patient with GAC accompanying ESCC, respectively. Patients with incidental GIST presented symptoms indistinguishable from those with EMT. All incidental GIST lesions were small in size, and the majority had a low mitotic activity while only 1.9% (5/257) of clinical GIST lesions had a high risk.CONCLUSION: Incidental GIST may occur synchronously with other tumors and has a high prevalence in males. Surgery is its best treatment modality.
文摘AIM： To identify patients with a high-risk of having a synchronous cancer among gastric cancer patients. METHODS： We retrospectively analyzed the prospective gastric cancer database at the National Cancer Center, Korea from December 2000 to December 2004. The clinicopathological characteristics of patients with synchronous cancers and those of patients without synchronous cancers were compared. Multivariate analysis was performed to identify the risk factors for the presence of a synchronous cancer in gastric cancer patients. RESULTS： 111 of 3291 gastric cancer patients （3.4%） registered in the database had a synchronous cancer. Among these 111 patients, 109 had a single synchronous cancer and 2 patients had two synchronous cancers. The most common form of synchronous cancer was colorectal cancer （42 patients, 37.2%） followed by lung cancer （21 patients, 18.6%）. Multivariate analyses revealed that elderly patients with differentiated early gastric cancer have a higher probability of a synchronous cancer. CONCLUSION： Synchronous cancers in gastric cancer patients are not infrequent. The physicians should try to find synchronous cancers in gastric cancer patients, especially in the elderly with a differentiated early gastric
文摘Laparoscopic resection of rectal cancer or gastric cancer has been advocated for the benefits of a reduced morbidity,a shorter treatment time,and similar outcomes.However,simultaneous laparoscopy-assisted low anterior resection and distal gastrectomy for synchronous carcinoma of rectum and stomach are rarely documented in literature.Endoscopic examination revealed a synchronous carcinoma of rectum and stomach in a 55-year-old male patient with rectal bleeding and epigastric discomfort.He underwent a simultaneous laparoscopy-assisted low anterior resection and distal gastrectomy with regional lymph nodes dissected.The operation time was 270 min and the estimated blood loss was 120 mL.The patient required parenteral analgesia for less than 24 h.Flatus was passed on postoperative day 3,and a solid diet was resumed on postoperative day 7.He was discharged on postoperative day 13.With the advances in laparoscopic technology and experience,simultaneous resection is an attractive alternative to a synchronous gastrointestinal cancer.
文摘To investigate predictive markers for metachronous and synchronous gastric cancer (GC), which can develop after endoscopic submucosal dissection (ESD). METHODSA total of 352 patients underwent ESD for early GC at NTT West Osaka Hospital between June 2006 and February 2016. Exclusion criteria were as follows: Remnant stomach, unknown Helicobacter pylori status, and endoscopic observation of the whole stomach outside our hospital. We analyzed data from 192 patients comprising 109 patients with solitary GC (Group A) and 83 with metachronous and synchronous GC (Group B). We retrospectively investigated the clinicopathological and endoscopic characteristics, and endoscopic risk score as predictive markers for GC. RESULTSThe median age of Group B [72 years (interquartile range 63-78)] was significantly higher than that of Group A [66 years (interquartile range 61-74), respectively, P = 0.0009]. The prevalence of intestinal metaplasia in Group B tended to be higher than that in Group A (57.8% vs 45.0%, P = 0.08). The prevalence of gastric xanthoma (GX) in Group B was significantly higher than that in Group A (54.2% vs 32.1%, P = 0.003). The atrophy score in Group B was significantly higher than that in Group A (P = 0.005). Multivariate analysis revealed that higher age and the presence of GX were independently related to metachronous and synchronous GC [OR = 1.04 (1.01-1.08), P = 0.02; and OR = 2.11 (1.14-3.99), P = 0.02, respectively]. CONCLUSIONThe presence of GX is a useful predictive marker for metachronous and synchronous GC.
