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Oligodendrocyte precursor cell-neuronal lysosomal pathway:A novel therapeutic target for neurodegenerative diseases
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作者 Li-Pao Fang Yibo Zhao Xianshu Bai 《Neural Regeneration Research》 2026年第6期2355-2356,共2页
Oligodendrocyte precursor cells(OPCs)tile the central nervous system ubiquitously,accounting for about 5%of the total cell population in the central nervous system.Beyond their role in myelination,OPCs actively shape ... Oligodendrocyte precursor cells(OPCs)tile the central nervous system ubiquitously,accounting for about 5%of the total cell population in the central nervous system.Beyond their role in myelination,OPCs actively shape neural circuits(Fang and Bai,2023),by releasing neuromodulators,pruning synapses,maintaining the homeostasis of extracellular potassium concentration,and interacting with endothelial cells. 展开更多
关键词 oligodendrocyte precursor cells opcs tile neuromodulatorspruning synapsesmaintaining oligodendrocyte precursor cells endothelial cells neuronal lysosomal pathway extracellular potassium central nervous systembeyond shape neural circuits fang
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