The article systematically summarizes the pathogen, incidence law and disease symptom of rice blast, and raises the integrated control technique for the disease, which will provide the certain theoretical basis for th...The article systematically summarizes the pathogen, incidence law and disease symptom of rice blast, and raises the integrated control technique for the disease, which will provide the certain theoretical basis for the control of the disease, being benefit for the actual production of rice in field.展开更多
We performed a meta-analysis to compare treatment with a combination of solifenacin plus tamsulosin oral controlled absorption system （TOCAS） with placebo or TOCAS monotherapy. The aim of the meta-analysis was to cl...We performed a meta-analysis to compare treatment with a combination of solifenacin plus tamsulosin oral controlled absorption system （TOCAS） with placebo or TOCAS monotherapy. The aim of the meta-analysis was to clarify the efficacy and safety of the combination treatments method for lower urinary tract symptoms （LUTS）. We searched for trials of men with LUTS that were randomized to combination treatment compared with TOCAS monotherapy or placebo. We pooled data from three placebo-controlled trials meeting inclusion criteria. Primary outcomes of interest included changes in International Prostate Symptom Score （IPSS） and urinary frequency. We also assessed postvoid residual, maximum urinary flow rate, incidence of urinary retention （UR）, adverse events. Data were pooled using random or fixed effect models for continuous outcomes and the ManteI-Haenszel method to generate risk ratio. Reductions in IPSS storage subscore and total urgency and frequency score （TUFS） were observed with solifenacin 6 mg plus TOCAS compared with placebo （P 〈 0.0001 and P 〈 0.0001, respectively）. Reductions in IPSS storage subscore and TUFS were observed with solifenacin 9 mg plus TOCAS compared with placebo （P= 0.003 and P = 0.0006, respectively）. Reductions in TUFS was observed with solifenacin 6 mg plus TOCAS compared with TOCAS （P = 0.01）. Both combination treatments were well tolerated, with low incidence of UR. Solifenacin 6 mg plus TOCAS significantly improved total IPSS, storage and voiding symptoms compared with placebo. Solifenacin 6 mg plus TOCAS also improved storage symptoms compared with TOCAS alone. There was no additional benefit of solifenacin 9 mg compared with 6 mg when used in combination with TOCAS.展开更多
The present study aims to investigate the effectiveness of dialectical behavior therapy in clinical symptoms, anger control and emotional regulation of bully children. This research is a pretest-posttest quasi-experim...The present study aims to investigate the effectiveness of dialectical behavior therapy in clinical symptoms, anger control and emotional regulation of bully children. This research is a pretest-posttest quasi-experimental study design with a nonequivalent control group. The research sample comprises 24 bully children who were purposefully selected from among the students who had responded positively to the researcher’s call. The participants were randomly assigned into two experimental and control groups. Group therapy intervention was conducted on the experimental group during ten sessions. The tools applied in this study consisted of Cognitive Emotion Regulation Questionnaire by Garnefski et al., State-Trait Anger Expression Inventory by Spielberger and Bullying Scale by Illinois, Espelage and Holt and the subjects answered to their questions in the stage of pretest and posttest. In this research, the data was analyzed based on the analysis of covariance test and with the aid of SPSS software. The findings demonstrated that dialectical behavior therapy has a significant impact on clinical symptoms, anger control and its components and emotional regulation and its components (P < 0.01).展开更多
AIM To determine the impact of upwards titration of proton pump inhibition(PPI)on acid reflux,symptom scores and histology,compared to clinically successful fundoplication.METHODS Two cohorts of long-segment Barrett&#...AIM To determine the impact of upwards titration of proton pump inhibition(PPI)on acid reflux,symptom scores and histology,compared to clinically successful fundoplication.METHODS Two cohorts of long-segment Barrett's esophagus(BE)patients were studied.In group 1(n=24),increasing doses of PPI were administered in 8-wk intervals until acid reflux normalization.At each assessment,ambulatory 24 h p H recording,endoscopy with biopsies and symptom scoring(by a gastroesophageal reflux disease health related quality of life questionnaire,GERD/HRLQ)were performed.Group 2(n=30)consisted of patients with a previous fundoplication.RESULTS In group 1,acid reflux normalized in 23 of 24 patients,resulting in improved GERD/HRQL scores(P=0.001),which were most pronounced after the starting dose of PPI(P<0.001).PPI treatment reached the same level of GERD/HRQL scores as after a clinically successful fundoplication(P=0.5).Normalization of acid reflux in both groups was associated with reduction in papillary length,basal cell layer thickness,intercellular space dilatation,and acute and chronic inflammation of squamous epithelium.CONCLUSION This study shows that acid reflux and symptom scores co-vary throughout PPI increments in long-segment BE patients,especially after the first dose of PPI,reaching the same level as after a successful fundoplication.Minor changes were found among GERD markers at the morphological level.展开更多
[ Objective] The study aimed to research the identification of Persimmon anthracnose and its controlling methods.[ Method ] The pathogen and characteristics, infection and occurrence law, damage symptoms of persimmon ...[ Objective] The study aimed to research the identification of Persimmon anthracnose and its controlling methods.[ Method ] The pathogen and characteristics, infection and occurrence law, damage symptoms of persimmon anthracnose were stated simply and the methods for con- trolling the disease were summed up. [ Result] The pathogen of Persimmon anthracnose was Gloeospor/um kaki Hod, belonging to Deuteromycotina. Germination and invasion of the conidia, sporulation and growth of mycelium all required high temperature, with the optimum temperature of 25 ℃ and the lethal temperature of 50 ℃ （10 min）. The occurrence strength of Persimmon anthracnose related with the factors including host, environment, culture circumstances, mainly doing harm to the fruits and branches. The occurrence of the disease could be controlled by such agricultur- al measures as cleaning the orchard, using the resistant varieties and planting the disease-free seedlings, adopting the balanced fertilization, improving the irrigation and drainage systems, conducting the dense planting and thin branches, building garden using the seedling that grafting on planted stock and raising the grafted parts of the stock. When the incidence was heavy, it needed to spray the fungicides or protective agent for the control of the Persimmon anthracnose. The fungicides should be mainly sprayed on the lesion of shoot, fruit surface and branches. [ Conclusion] The study provided the reference for the control of the Persimmon anthracnose.展开更多
OBJECTIVE:To evaluate the effectiveness and safety of acupuncture that reinforces the spleen to strengthen the lung in patients with stable chronic obstructive pulmonary disease(COPD).METHODS:This was a randomized,ope...OBJECTIVE:To evaluate the effectiveness and safety of acupuncture that reinforces the spleen to strengthen the lung in patients with stable chronic obstructive pulmonary disease(COPD).METHODS:This was a randomized,open-controlled trial in which the acupuncturist and the participants were not blinded,but the outcome evalu-ators and data analysts were blinded.One-hundred-and-two patients with stable COPD were randomly divided into two groups in a 1∶1 ratio.The acupuncture group received 30-minute sessions of acupuncture therapy at the same acupoints three times weekly for 6 weeks in addition to routine conventional Western Medicine treatment;the control group received routine conventional Western Medicine treatment alone.The primary outcome was the Borg scale score,which was assessed immediately after the 6-minute walk test.The secondary outcomes were the 6-minute walk distance,lung function,and oxygen saturation.Measurements were obtained at baseline and after 6 weeks of treatment.RESULTS:After 6 weeks of treatment,the Borg scale score in the acupuncture group was significantly better than that in the control group(2.02±0.71 versus 5.01±0.34,P<0.05).Furthermore,the post-treatment improvements in the 6-minute walk distance,lung function,and oxygen saturation were significantly greater in the acupuncture group than in the control group,showing that the acupuncture group had better exercise tolerance.CONCLUSION:The findings suggest that acupuncture that aims to reinforce the spleen to strengthen the lung is a safe and effective adjuvant therapy that effectively improves the exercise capacity of patients with stable COPD.展开更多
Background: Insomnia is a common complaint that is closely related to gastrointestinal symptoms, which is consistent with the traditional Chinese medicine classical theory of ‘‘stomach disharmony leading to restless...Background: Insomnia is a common complaint that is closely related to gastrointestinal symptoms, which is consistent with the traditional Chinese medicine classical theory of ‘‘stomach disharmony leading to restless sleep." Acupuncture is an effective complementary and alternative medicine therapy to improve gastrointestinal function and restore the normal sleep-wake cycle. However, studies on the effectiveness of acupuncture for insomnia due to spleen-stomach disharmony syndrome are limited to case reports and few randomized controlled trials; deeper research on its mechanism is still lacking. This randomized controlled trial aims to assess the treatment efficacy of ‘‘harmonizing stomach to tranquilize mind"acupuncture for insomnia and its influence on the intestinal microbiome.Methods/design: This is a randomized, single-blind, parallel-group study. Sixty eligible patients with insomnia due to spleen-stomach disharmony syndrome will be randomly divided into two groups(1:1 allocation ratio). The intervention group will use ‘‘harmonizing stomach to tranquilize mind"acupuncture, and the control group will receive sham acupuncture. Participants will receive 5 acupuncture treatment sessions per week for 4 consecutive weeks. The Pittsburgh Sleep Quality Index will be used to evaluate the clinical efficacy of acupuncture treatment by making assessments at baseline, the end of treatment and the end of the follow-up. High-throughput 16 S ribosomal ribonucleic acid gene sequencing will be performed to detect changes in the intestinal microbial composition before and after treatment.Discussion: The results of this trial are expected to confirm that ‘‘harmonizing stomach to tranquilize mind" acupuncture can effectively relieve insomnia and alter the intestinal microbiome.展开更多
文摘The article systematically summarizes the pathogen, incidence law and disease symptom of rice blast, and raises the integrated control technique for the disease, which will provide the certain theoretical basis for the control of the disease, being benefit for the actual production of rice in field.
文摘We performed a meta-analysis to compare treatment with a combination of solifenacin plus tamsulosin oral controlled absorption system （TOCAS） with placebo or TOCAS monotherapy. The aim of the meta-analysis was to clarify the efficacy and safety of the combination treatments method for lower urinary tract symptoms （LUTS）. We searched for trials of men with LUTS that were randomized to combination treatment compared with TOCAS monotherapy or placebo. We pooled data from three placebo-controlled trials meeting inclusion criteria. Primary outcomes of interest included changes in International Prostate Symptom Score （IPSS） and urinary frequency. We also assessed postvoid residual, maximum urinary flow rate, incidence of urinary retention （UR）, adverse events. Data were pooled using random or fixed effect models for continuous outcomes and the ManteI-Haenszel method to generate risk ratio. Reductions in IPSS storage subscore and total urgency and frequency score （TUFS） were observed with solifenacin 6 mg plus TOCAS compared with placebo （P 〈 0.0001 and P 〈 0.0001, respectively）. Reductions in IPSS storage subscore and TUFS were observed with solifenacin 9 mg plus TOCAS compared with placebo （P= 0.003 and P = 0.0006, respectively）. Reductions in TUFS was observed with solifenacin 6 mg plus TOCAS compared with TOCAS （P = 0.01）. Both combination treatments were well tolerated, with low incidence of UR. Solifenacin 6 mg plus TOCAS significantly improved total IPSS, storage and voiding symptoms compared with placebo. Solifenacin 6 mg plus TOCAS also improved storage symptoms compared with TOCAS alone. There was no additional benefit of solifenacin 9 mg compared with 6 mg when used in combination with TOCAS.
文摘The present study aims to investigate the effectiveness of dialectical behavior therapy in clinical symptoms, anger control and emotional regulation of bully children. This research is a pretest-posttest quasi-experimental study design with a nonequivalent control group. The research sample comprises 24 bully children who were purposefully selected from among the students who had responded positively to the researcher’s call. The participants were randomly assigned into two experimental and control groups. Group therapy intervention was conducted on the experimental group during ten sessions. The tools applied in this study consisted of Cognitive Emotion Regulation Questionnaire by Garnefski et al., State-Trait Anger Expression Inventory by Spielberger and Bullying Scale by Illinois, Espelage and Holt and the subjects answered to their questions in the stage of pretest and posttest. In this research, the data was analyzed based on the analysis of covariance test and with the aid of SPSS software. The findings demonstrated that dialectical behavior therapy has a significant impact on clinical symptoms, anger control and its components and emotional regulation and its components (P < 0.01).
文摘AIM To determine the impact of upwards titration of proton pump inhibition(PPI)on acid reflux,symptom scores and histology,compared to clinically successful fundoplication.METHODS Two cohorts of long-segment Barrett's esophagus(BE)patients were studied.In group 1(n=24),increasing doses of PPI were administered in 8-wk intervals until acid reflux normalization.At each assessment,ambulatory 24 h p H recording,endoscopy with biopsies and symptom scoring(by a gastroesophageal reflux disease health related quality of life questionnaire,GERD/HRLQ)were performed.Group 2(n=30)consisted of patients with a previous fundoplication.RESULTS In group 1,acid reflux normalized in 23 of 24 patients,resulting in improved GERD/HRQL scores(P=0.001),which were most pronounced after the starting dose of PPI(P<0.001).PPI treatment reached the same level of GERD/HRQL scores as after a clinically successful fundoplication(P=0.5).Normalization of acid reflux in both groups was associated with reduction in papillary length,basal cell layer thickness,intercellular space dilatation,and acute and chronic inflammation of squamous epithelium.CONCLUSION This study shows that acid reflux and symptom scores co-vary throughout PPI increments in long-segment BE patients,especially after the first dose of PPI,reaching the same level as after a successful fundoplication.Minor changes were found among GERD markers at the morphological level.
基金Supported by National"Eleventh Five-Year"Technology Support Pro-ject(2006BAD09B07,2006BAD09B09,2007BAD88B04)~~
文摘[ Objective] The study aimed to research the identification of Persimmon anthracnose and its controlling methods.[ Method ] The pathogen and characteristics, infection and occurrence law, damage symptoms of persimmon anthracnose were stated simply and the methods for con- trolling the disease were summed up. [ Result] The pathogen of Persimmon anthracnose was Gloeospor/um kaki Hod, belonging to Deuteromycotina. Germination and invasion of the conidia, sporulation and growth of mycelium all required high temperature, with the optimum temperature of 25 ℃ and the lethal temperature of 50 ℃ （10 min）. The occurrence strength of Persimmon anthracnose related with the factors including host, environment, culture circumstances, mainly doing harm to the fruits and branches. The occurrence of the disease could be controlled by such agricultur- al measures as cleaning the orchard, using the resistant varieties and planting the disease-free seedlings, adopting the balanced fertilization, improving the irrigation and drainage systems, conducting the dense planting and thin branches, building garden using the seedling that grafting on planted stock and raising the grafted parts of the stock. When the incidence was heavy, it needed to spray the fungicides or protective agent for the control of the Persimmon anthracnose. The fungicides should be mainly sprayed on the lesion of shoot, fruit surface and branches. [ Conclusion] The study provided the reference for the control of the Persimmon anthracnose.
基金Supported by the Science Projects of Administration of Traditional Chinese Medicine of Sichuan(No.2016C067)
文摘OBJECTIVE:To evaluate the effectiveness and safety of acupuncture that reinforces the spleen to strengthen the lung in patients with stable chronic obstructive pulmonary disease(COPD).METHODS:This was a randomized,open-controlled trial in which the acupuncturist and the participants were not blinded,but the outcome evalu-ators and data analysts were blinded.One-hundred-and-two patients with stable COPD were randomly divided into two groups in a 1∶1 ratio.The acupuncture group received 30-minute sessions of acupuncture therapy at the same acupoints three times weekly for 6 weeks in addition to routine conventional Western Medicine treatment;the control group received routine conventional Western Medicine treatment alone.The primary outcome was the Borg scale score,which was assessed immediately after the 6-minute walk test.The secondary outcomes were the 6-minute walk distance,lung function,and oxygen saturation.Measurements were obtained at baseline and after 6 weeks of treatment.RESULTS:After 6 weeks of treatment,the Borg scale score in the acupuncture group was significantly better than that in the control group(2.02±0.71 versus 5.01±0.34,P<0.05).Furthermore,the post-treatment improvements in the 6-minute walk distance,lung function,and oxygen saturation were significantly greater in the acupuncture group than in the control group,showing that the acupuncture group had better exercise tolerance.CONCLUSION:The findings suggest that acupuncture that aims to reinforce the spleen to strengthen the lung is a safe and effective adjuvant therapy that effectively improves the exercise capacity of patients with stable COPD.
基金supported by a grant from the Science and Technology Planned Project of Sichuan Province,China (No.18YYJC0949)
文摘Background: Insomnia is a common complaint that is closely related to gastrointestinal symptoms, which is consistent with the traditional Chinese medicine classical theory of ‘‘stomach disharmony leading to restless sleep." Acupuncture is an effective complementary and alternative medicine therapy to improve gastrointestinal function and restore the normal sleep-wake cycle. However, studies on the effectiveness of acupuncture for insomnia due to spleen-stomach disharmony syndrome are limited to case reports and few randomized controlled trials; deeper research on its mechanism is still lacking. This randomized controlled trial aims to assess the treatment efficacy of ‘‘harmonizing stomach to tranquilize mind"acupuncture for insomnia and its influence on the intestinal microbiome.Methods/design: This is a randomized, single-blind, parallel-group study. Sixty eligible patients with insomnia due to spleen-stomach disharmony syndrome will be randomly divided into two groups(1:1 allocation ratio). The intervention group will use ‘‘harmonizing stomach to tranquilize mind"acupuncture, and the control group will receive sham acupuncture. Participants will receive 5 acupuncture treatment sessions per week for 4 consecutive weeks. The Pittsburgh Sleep Quality Index will be used to evaluate the clinical efficacy of acupuncture treatment by making assessments at baseline, the end of treatment and the end of the follow-up. High-throughput 16 S ribosomal ribonucleic acid gene sequencing will be performed to detect changes in the intestinal microbial composition before and after treatment.Discussion: The results of this trial are expected to confirm that ‘‘harmonizing stomach to tranquilize mind" acupuncture can effectively relieve insomnia and alter the intestinal microbiome.
