BACKGROUND Stapes ankylosis is a rare cause of conductive hearing loss,and stapes suprastructure fixation is extremely rare with fewer than 30 reported cases.Patients usually visit the clinic with non-progressive cond...BACKGROUND Stapes ankylosis is a rare cause of conductive hearing loss,and stapes suprastructure fixation is extremely rare with fewer than 30 reported cases.Patients usually visit the clinic with non-progressive conductive hearing loss that typically began in the early years of life.CASE SUMMARY Herein,we report a case of a 37-year-old female with an isolated stapedial suprastructure fixation.The patient presented with unusual fluctuating auditory symptoms of tinnitus,ear fullness and mixed hearing loss.Pre-operative temporal bone computed tomography findings and operative findings revealed an isolated stapedial suprastructure fixation with monopod stapes caused by elongated pyramidal eminence.The hearing threshold recovered completely,and fluctuating auditory symptoms disappeared after the surgery.CONCLUSION This is the first report of stapedial suprastructure fixation with fluctuating auditory symptoms.Successful results are expected with surgical treatment.展开更多
Densely packed and ordered ＂suprastructures＂ are new types of nanomaterials exhibiting broad applications. The direct self-assembly of cetyltrimethylammonium bromide （CTAB）-capped gold nanotriangles to form ＂supr...Densely packed and ordered ＂suprastructures＂ are new types of nanomaterials exhibiting broad applications. The direct self-assembly of cetyltrimethylammonium bromide （CTAB）-capped gold nanotriangles to form ＂suprastructures＂ was systematically investigated by varying the temperature and tilt angle of the silicon wafer used in the assembly process. Under optimal conditions, nanotriangles form into regular patterns, maintain their integrity, and form edge-to-edge, point-to-point, and face-to-face connections to form ordered ＂suprastructures＂ within an area of hundreds of square microns, achieving a high level of regularity. The formation of the ＂suprastructures＂ under optimal conditions could be mainly attributed to the complex balance between multiple temperature-dependent factors, including the atom diffusion rate, solvent evaporation rate, self-assembly rate, and the time for which the nanoparticle stays in the wet medium.展开更多
文摘BACKGROUND Stapes ankylosis is a rare cause of conductive hearing loss,and stapes suprastructure fixation is extremely rare with fewer than 30 reported cases.Patients usually visit the clinic with non-progressive conductive hearing loss that typically began in the early years of life.CASE SUMMARY Herein,we report a case of a 37-year-old female with an isolated stapedial suprastructure fixation.The patient presented with unusual fluctuating auditory symptoms of tinnitus,ear fullness and mixed hearing loss.Pre-operative temporal bone computed tomography findings and operative findings revealed an isolated stapedial suprastructure fixation with monopod stapes caused by elongated pyramidal eminence.The hearing threshold recovered completely,and fluctuating auditory symptoms disappeared after the surgery.CONCLUSION This is the first report of stapedial suprastructure fixation with fluctuating auditory symptoms.Successful results are expected with surgical treatment.
基金Dr. Mattew R. Jones and Prof. Paul Alivisatos from UC Berkeley are appreciated for the valuable discussion about the self-assembly mechanism. This work was supported by the National Basic Research Program of China （973 Program, Nos. 2012CB932800 and 2014CB932700）, National Natural Science Foundation of China （Nos. 21422307, 21303180, 21433003, 21503212, and 21503211）, the ＂Recruitment Program of Global youth Experts＂ of China, Shenzhen Science and Technology Foundation （No. JCYJ20140418182819116）, and the Natural Science Foundation of SZU （No. 201447）.
文摘Densely packed and ordered ＂suprastructures＂ are new types of nanomaterials exhibiting broad applications. The direct self-assembly of cetyltrimethylammonium bromide （CTAB）-capped gold nanotriangles to form ＂suprastructures＂ was systematically investigated by varying the temperature and tilt angle of the silicon wafer used in the assembly process. Under optimal conditions, nanotriangles form into regular patterns, maintain their integrity, and form edge-to-edge, point-to-point, and face-to-face connections to form ordered ＂suprastructures＂ within an area of hundreds of square microns, achieving a high level of regularity. The formation of the ＂suprastructures＂ under optimal conditions could be mainly attributed to the complex balance between multiple temperature-dependent factors, including the atom diffusion rate, solvent evaporation rate, self-assembly rate, and the time for which the nanoparticle stays in the wet medium.
