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Design of insulation support system of 120 keV positive ion source accelerator
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作者 Wen DENG Yahong XIE +5 位作者 Yuming GU Yunfei JIANG Longbin LIU Fang WANG Jianglong WEI Chundong HU 《Plasma Science and Technology》 2025年第1期128-133,共6页
In order to support the physical research on the EAST tokamak,a new positive ion source with designed beam energy of 120 keV was proposed to be developed.Accelerator structure is one of the key components of the ion s... In order to support the physical research on the EAST tokamak,a new positive ion source with designed beam energy of 120 keV was proposed to be developed.Accelerator structure is one of the key components of the ion source.Through the finite element analysis method,the electrostatic analyses of insulators and grid plates were carried out,the material and structure parameters of insulators were determined.The maximum electric field around each insulator is about 4 kV/mm,and the maximum electric field between grids is about 14 kV/mm,which can meet the 120 keV withstand voltage holding.The insulation system for the positive ion source accelerator with 120 keV is designed,and the connection and basic parameters of insulators and support flanges are analyzed and determined. 展开更多
关键词 positive ion source ACCELERATOR insulation support system electrostatic simulation
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AquaVar decision support system for water resource management:Lessons learned from the first five years of operation
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作者 Fanny Picourlat Lian Guey Ler +4 位作者 Jérémy Targosz Paguedame Game HézouwéAmaou Tallé Morgan Abily Félix Billaud 《River》 2025年第1期44-54,共11页
Decision support systems(DSS)based on physically based numerical models are standard tools used by water services and utilities.However,few DSS based on holistic approaches combining distributed hydrological,hydraulic... Decision support systems(DSS)based on physically based numerical models are standard tools used by water services and utilities.However,few DSS based on holistic approaches combining distributed hydrological,hydraulic,and hydrogeological models are operationally exploited.This holistic approach was adopted for the development of the AquaVar DSS,used for water resource management in the French Mediterranean Var watershed.The year 2019 marked the initial use of the DSS in its operational environment.Over the next 5 years,multiple hydrological events allowed to test the performance of the DSS.The results show that the tool is capable of simulating peak flows associated with two extreme rainfall events(storms Alex and Aline).For a moderate flood,the real-time functionality was able to simulate forecast discharges 26 h before the flood peak,with a maximum local error of 30%.Finally,simulations for the drought period 2022-2023 highlighted the essential need for DSS to evolve in line with changing climatic conditions,which give rise to unprecedented hydrological processes.The lessons learned from these first 5 years of AquaVar use under operational conditions are synthesized,addressing various topics such as DSS modularity,evolution,data positioning,technology,and governance. 展开更多
关键词 decision support system distributed physically based models holistic approach water resource management
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Effects of the support system combined with Chinese medicine on postoperative gastrointestinal recovery in patients with liver cancer
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作者 Ting-Ting Luo Meng-Yun Dong +1 位作者 Si Zhao Xue-Zhen Zhai 《World Journal of Gastrointestinal Oncology》 2025年第8期87-94,共8页
BACKGROUND The treatment of patients with liver cancer after surgery with the artificial liver support system combined with traditional Chinese medicine(TCM)for strengthening the body and removing blood stasis is a ne... BACKGROUND The treatment of patients with liver cancer after surgery with the artificial liver support system combined with traditional Chinese medicine(TCM)for strengthening the body and removing blood stasis is a new idea.AIM To analyze the post-surgical effect of the artificial liver support system with TCM in patients with liver cancer.METHODS Ninety-eight patients with liver cancer who underwent surgical treatment at the Fifth People’s Hospital of Huai’an from January 2023-2024 were selected and divided into two groups(49 patients each)via random lottery method.Both groups underwent surgery.The control group received artificial liver support,and the observation group was additionally treated with TCM for strengthening the body and removing blood stasis.Gastrointestinal recovery,liver function,tumor marker levels,immune function,and safety were compared between both groups.RESULTS There were significant differences in the levels of indicators related to gastrointestinal recovery between the groups(P<0.05).After treatment,the levels of alanine aminotransferase,aspartate aminotransferase,total bilirubin,and gamma-glutamyl transpeptidase in the observation group were lower,whereas the albumin level was higher(P<0.05).After treatment,tumor marker levels in the observation group were relatively lower(P<0.05).After treatment,compared to the control group,the CD4+level in the observation group was higher and the CD8+level was lower(P<0.05).There was no significant difference in the incidence of adverse reactions between both groups(P>0.05).CONCLUSION Combining the artificial liver support system with TCM significantly improves liver and gastrointestinal functions,enhances immune responses,and reduces tumor marker levels with high safety,suggesting that it could be a promising approach for optimizing postoperative care and improving patient outcomes,potentially reducing complications and enhancing quality of life. 展开更多
关键词 Artificial liver support system Traditional Chinese medicine Agents for strengthening the body and removing blood stasis Liver cancer POSTOPERATIVE Liver function
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Protecting the Mental Health of Esports Players:A Qualitative Case Study on Their Stress,Coping Strategies,and Social Support Systems
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作者 Young-Vin Kim Hyunkyun Ahn 《International Journal of Mental Health Promotion》 2025年第9期1301-1334,共34页
Objectives:Recently,the global esports industry has experienced remarkable growth,leading to an expansion in the scale and influence of professional player communities.However,despite this outward growth,systems to pr... Objectives:Recently,the global esports industry has experienced remarkable growth,leading to an expansion in the scale and influence of professional player communities.However,despite this outward growth,systems to protect players’mental health remain inadequate.Comprehensive analysis of structural risk factors,including performance pressure,public evaluation,and career instability,remains insufficient.This study,aimed to explore stressors encountered by esports athletes,coping strategies,and the role of social support systems in safeguarding mental health.Using the transactional model of stress and coping,the job demands–resources model,and social support theory,the study adopts an integrated perspective to examine challenges faced by athletes in the competitive esports environment.Methods:A qualitative case study was conducted involving in-depth interviews and nonparticipant observations with 11 esports athletes who competed at national or international levels,as well as two team managers.Thematic analysis identified recurring patterns in the data,and credibility was ensured through triangulation and cross-review among researchers.Results:Esports athletes experience multiple interacting stressors,including performance demands,emotional strain duringmatches,and continuous evaluation on socialmedia.In response,they employed coping strategies—problem-focused,emotion-focused,and avoidance-based,which provided temporary relief but often led to burnout and self-regulation failure owing to absence of support systems.Social support networks had ambivalent effects:while offering comfort,they also intensified pressure through negative feedback and high expectations from fans and online communities.Conclusion:The findings show that mental health issues among esports athletes are not only related to individual factors but are closely linked to performance-driven structures,competitive environments,and social relationships.This study integrates the transactional model of stress and coping,the JobDemands–Resourcesmodel,and social support theoryto provide comprehensive analysis.It also offers practical recommendations,including psychological counseling,emotional labor programs,and improved communication with families and fan communities. 展开更多
关键词 Esports esports athletes players’mental health multifaceted stressors coping strategies social support systems job demands-resources model performance-driven demands
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An Intelligent Decision Support System Generator
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作者 Shi Zhenxia and Lu JukangDept. of Computer Science, Shanghai Univ. of Science and Technology, Shanghai 201800, P.R. China 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 1993年第1期45-52,共8页
The focus of this paper is on a new concept framework and an architecture of an intelligent decision support syetem generator (DSSG). The framework results from a synthesis of two existing frameworks: Spragae and Bonc... The focus of this paper is on a new concept framework and an architecture of an intelligent decision support syetem generator (DSSG). The framework results from a synthesis of two existing frameworks: Spragae and Bonczek, while the architecture is a rooted partial order network. From our experience which comes out of the project of DSSG, we consider that they are keys of further research and development of DSS. 展开更多
关键词 Decision support system Decision support system generator Intelligent decision support system AI technology Hypertext technology.
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Study and Implementation on the Grey Comprehensive Evaluation Support System of Ecocity 被引量:2
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作者 黄鹍 陈森发 +1 位作者 孙燕 亓霞 《Journal of Southeast University(English Edition)》 EI CAS 2002年第4期356-360,共5页
According to basic connotation and design principles of ecocity, a comparatively integrated index system is constructed in the paper. And at the same time using hierarchy grey comprehensive evaluation method, a hierar... According to basic connotation and design principles of ecocity, a comparatively integrated index system is constructed in the paper. And at the same time using hierarchy grey comprehensive evaluation method, a hierarchy grey comprehensive evaluation model of ecocity is established, then on the basis of the model, a comprehensive evaluation support system is developed, and the theoretical guidance supplied for construction of ecocity is provided. 展开更多
关键词 ecocity index system evaluating level hierarchy grey comprehensive evaluation evaluation support system
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Method of Establishing Object-Oriented System Structure for Decision Support System 被引量:2
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作者 曹元大 胡军 管春 《Journal of Beijing Institute of Technology》 EI CAS 2002年第3期311-315,共5页
In order to solve existing problems about the method of establishing traditional system structure of decision support system(DSS), O S chart is applied to describe object oriented system structure of general DSS, an... In order to solve existing problems about the method of establishing traditional system structure of decision support system(DSS), O S chart is applied to describe object oriented system structure of general DSS, and a new method of eight specific steps is proposed to establish object oriented system structure of DSS by using the method of O S chart, which is applied successfully to the development of the DSS for the energy system ecology engineering research of the Wangheqiu country. Supplying many scientific effective computing models, decision support ways and a lot of accurate reliable decision data, the DSS plays a critical part in helping engineering researchers to make correct decisions. Because the period for developing the DSS is relatively shorter, the new way improves the efficiency of establishing DSS greatly. It also makes the DSS of system structure more flexible and easy to expand. 展开更多
关键词 decision support system object oriented technology system structure
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Beyond the Classroom Walls:Parental Attitudes,Support Systems,and the Struggle for Fluency among Turkish University EFL Learners
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作者 Dandyson Michael Jaja 《Sociology Study》 2025年第6期275-285,共11页
Language education has predominantly focused on classroom instruction and pedagogical strategies,yet the sociological aspects of learning-especially the family’s role-are often overlooked in English as a Foreign Lang... Language education has predominantly focused on classroom instruction and pedagogical strategies,yet the sociological aspects of learning-especially the family’s role-are often overlooked in English as a Foreign Language(EFL)contexts.This study explores how parental attitudes,support systems,and disciplinary approaches influence Turkish university students’oral fluency in English.While educators and curricula are frequently held accountable for low communicative competence,this paper posits that sociocultural factors originating from the home environment play a crucial role.Utilizing a qualitative-dominant mixed-methods design with 210 undergraduate EFL learners and 24 lecturers from four Turkish universities,data were gathered through questionnaires,interviews,and parental focus groups.Findings indicate that students with supportive and engaged parents exhibit greater self-efficacy,confidence,and linguistic agency in communication tasks.In contrast,those from indifferent or authoritarian families experience anxiety,low motivation,and stagnation in oral skills.Grounded in Bourdieu’s social capital theory,Bronfenbrenner’s ecological systems theory,and Coleman’s social context of learning,this study conceptualizes the family as an“invisible classroom”where linguistic habits,discipline,and cultural aspirations are cultivated.The paper concludes by proposing a Family-Engaged EFL Fluency Model(FE-EFM)that integrates learner development within a framework of sociological co-responsibility involving parents,educators,and institutions. 展开更多
关键词 parental attitudes social capital EFL fluency learner agency sociological education Turkish higher education family support
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Bearing characteristics of anchor box beam support system in deep thick roof coal roadway and its application
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作者 WANG Qi WANG Ming-zi +1 位作者 JIANG Bei XU Chuan-jie 《Journal of Central South University》 2025年第5期1887-1902,共16页
Considering the characteristics of deep thick top coal roadway,in which the high ground stress,coal seam with low strength,and a large range of surrounding rock fragmentation,the pressure relief anchor box beam suppor... Considering the characteristics of deep thick top coal roadway,in which the high ground stress,coal seam with low strength,and a large range of surrounding rock fragmentation,the pressure relief anchor box beam support system with high strength is developed.The high-strength bearing characteristics and coupling yielding support mechanism of this support system are studied by the mechanical tests of composite members and the combined support system.The test results show that under the coupling effect of support members,the peak stress of the box-shaped support beam in the anchor box beam is reduced by 21.9%,and the average deformation is increased by 135.0%.The ultimate bending bearing capacity of the box-shaped support beam is 3.5 times that of traditional channel beam.The effective compressive stress zone applied by the high prestressed cable is expanded by 26.4%.On this basis,the field support comparison test by the anchor channel beam,the anchor I-shaped beam and the anchor box beam are carried out.Compared with those of the previous two,the surrounding rock convergence of the latter is decreased by 41.2%and 22.2%,respectively.The field test verifies the effectiveness of the anchor box beam support system. 展开更多
关键词 thick roof coal roadway anchor box beam bearing characteristics combined support field application
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Developing a diagnostic support system for audiogram interpretation using deep learning-based object detection
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作者 Titipat Achakulvisut Suchanon Phanthong +4 位作者 Thanawut Timpitak Kanpat Vesessook Sirinan Junthong Withita Utainrat Kanokrat Bunnag 《Journal of Otology》 2025年第1期26-32,共7页
Objective To develop and evaluate an automated system for digitizing audiograms,classifying hearing loss levels,and comparing their performance with traditional methods and otolaryngologists'interpretations.Design... Objective To develop and evaluate an automated system for digitizing audiograms,classifying hearing loss levels,and comparing their performance with traditional methods and otolaryngologists'interpretations.Designed and Methods We conducted a retrospective diagnostic study using 1,959 audiogram images from patients aged 7 years and older at the Faculty of Medicine,Vajira Hospital,Navamindradhiraj University.We employed an object detection approach to digitize audiograms and developed multiple machine learning models to classify six hearing loss levels.The dataset was split into 70%training(1,407 images)and 30%testing(352 images)sets.We compared our model's performance with classifications based on manually extracted audiogram values and otolaryngologists'interpretations.Result Our object detection-based model achieved an F1-score of 94.72%in classifying hearing loss levels,comparable to the 96.43%F1-score obtained using manually extracted values.The Light Gradient Boosting Machine(LGBM)model is used as the classifier for the manually extracted data,which achieved top performance with 94.72%accuracy,94.72%f1-score,94.72 recall,and 94.72 precision.In object detection based model,The Random Forest Classifier(RFC)model showed the highest 96.43%accuracy in predicting hearing loss level,with a F1-score of 96.43%,recall of 96.43%,and precision of 96.45%.Conclusion Our proposed automated approach for audiogram digitization and hearing loss classification performs comparably to traditional methods and otolaryngologists'interpretations.This system can potentially assist otolaryngologists in providing more timely and effective treatment by quickly and accurately classifying hearing loss. 展开更多
关键词 AUDIOGRAM Deep machine learning Training set Validation set Testing set Automatic Machine Learning(AutoML) Random Forest Classifier(RFC) support Vector Machine(SVM) XGBoost
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Method for designing organization decision support system framework 被引量:1
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作者 Fan Jiancong Liang Yongquan Zeng Qingtian 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2006年第4期764-768,共5页
The concept of organization decision support system (ODSS) is defined according to practical applications and novel understanding. And a framework for ODSS is designed. The framework has three components: infrastru... The concept of organization decision support system (ODSS) is defined according to practical applications and novel understanding. And a framework for ODSS is designed. The framework has three components: infrastructure, decision-making process and decision execution process. Infrastructure is responsible to transfer data and information. Decision-making process is the ODSS's soul to support decision-making. Decision execution process is to evaluate and execute decision results derived from decision-making process. The framework presents a kind of logic architecture. An example is given to verify and analyze the framework. The analysis shows that the framework has practical values, and has also reference values for understanding ODSS and for theoretical studies. 展开更多
关键词 terms-decision support system organization decision organization decision support system.
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Review of the creativity support system
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作者 冯勤超 范伟伟 孙锦 《Journal of Southeast University(English Edition)》 EI CAS 2007年第S1期173-178,共6页
Based on the achievements of domestic and foreign scholars,the concept of the creativity support system(CSS)is introduced and two basic characteristics of the CSS are concluded:one is based on information technology,t... Based on the achievements of domestic and foreign scholars,the concept of the creativity support system(CSS)is introduced and two basic characteristics of the CSS are concluded:one is based on information technology,the other is assisting users in creatively solving problems.Then,the rationale as well as the correlative knowledge of the creativity support system is analyzed.Finally,according to the software that has been developed,the creativity support system's characteristics of the function is discussed. 展开更多
关键词 artificial intelligence CREATIVITY COGNITION creativity support system
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Research and Application of Maize Precision Intelligence Spatial Decision Support System
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作者 王国伟 陈桂芬 +1 位作者 姚玉霞 闫丽 《Agricultural Science & Technology》 CAS 2010年第6期147-151,188,共6页
In order to solve the problem of the maze precision fertilizer,soil fertility evaluation,soil fertility classify and yield projections,the geographic information system with spatial information processing functions,sp... In order to solve the problem of the maze precision fertilizer,soil fertility evaluation,soil fertility classify and yield projections,the geographic information system with spatial information processing functions,spatial data mining techniques with spatial information analysis capabilities,expert system technology in the field of artificial intelligence,traditional information management systems and decision support system were effectively integrated in this study,and the statistical analysis method of GIS and data visualization were combined to design and implement the maize precise intelligent space decision-making system.This system had greatly improved the decision-making ability in agricultural production carried out by agricultural management. 展开更多
关键词 Maize precision operation Space data mining Decision support system Geographic information system VISUALIZATION
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Study on the Decision Support System for Northing of Winter Wheat Cultivation in Hebei Province
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作者 邹立坤 蓝岚 李小娟 《Agricultural Science & Technology》 CAS 2012年第3期630-633,637,共5页
[Objective] This study was to provide methods to improve the scientificity and informatization level of agricultural decision-making system based on the study of Decision Support System for "Northing of Winter Wheat... [Objective] This study was to provide methods to improve the scientificity and informatization level of agricultural decision-making system based on the study of Decision Support System for "Northing of Winter Wheat" in Hebei Province (DSS- NWWH). [Method] The functions, development process, operation guidance as well as input and output modes of DSSNWWH were introduced, and the simulated results of the system were verified by comparing with the actual situations. [Result] The decision support system established in this study could predict whether a wheat variety could live through the winter in a certain area of northern Hebei Province, as well as the growth conditions based on the previous meteorological data or local weather forecast, and provided corresponding cultivation and management measures, making it possible for the user to determine whether the variety could be planted in the region based on the predictions. [Conclusion] The established DSSNWWH in this study can effectively help decision makers make decisions, providing scientific instructions for the northing of winter wheat. 展开更多
关键词 Winter wheat Growing in northern region Decision support system
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SUPPORT SYSTEM FOR FREE SURFACE GRINDING BASED ON PATCH DIVISION
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作者 吴晓君 喜田羲宏 孙树栋 《Transactions of Nanjing University of Aeronautics and Astronautics》 EI 2005年第4期291-297,共7页
To obtain accurate forms and surfaces in free surface grinding, it is important to provide grinding conditions suitable for a curved surface. A grinding support system for the free surface (GSX-F) is proposed to hel... To obtain accurate forms and surfaces in free surface grinding, it is important to provide grinding conditions suitable for a curved surface. A grinding support system for the free surface (GSX-F) is proposed to help the operator grind a free surface with the high accuracy and the high productivity. To succeed in free surface grinding, the property of a ball type wheel must be known. Therefore, a basic study of free surface grinding with a ball type wheel is carried out based on the grinding center (GC). Some working points for achieving sufficient accuracy in free surface grinding are discussed. GSX-F is constructed using the patch division method and is used to test grinding. Reasonable results are obtained. 展开更多
关键词 grinding center ball type wheel support system free surface grinding patch division
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DEVELOPING EXPERT DECISION SUPPORT SYSTEM WTH VP-EXPERT AND LOTUS 1-2-3 IN RE-BLENDING BY USE
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作者 舒航 杨鹏 《Journal of China University of Mining and Technology》 1994年第2期104-111,共8页
An expert decision support system (EDSS) for multi-bins balance and contro1 of orequality in production ore bins of some large-scale open pit iron mine in China has been developed byexpert svitem tool software VP-EXPE... An expert decision support system (EDSS) for multi-bins balance and contro1 of orequality in production ore bins of some large-scale open pit iron mine in China has been developed byexpert svitem tool software VP-EXPERT and integration software LOTUS 1-2-3 in this paper. Itis known by practicing that a medium-scale EDSS constructed on microcomputer is completcly, feaasible by means of VP-EXEPERT to construct knowledge base system (KBS), LOTUS 1-2-3 tomake decision support system (DSS) and link them with BAT. 展开更多
关键词 VP-EXPERT LOTUS 1-2-3 ore-blending expert system decision support system expert decision support system
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Mechanism of wet shotcrete interacting with rock in support systems 被引量:18
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作者 李莉 吴爱祥 +3 位作者 王贻明 韩斌 王洪江 王春来 《Journal of Central South University》 SCIE EI CAS 2013年第3期821-829,共9页
In order to have a good understanding of the behavior of wet shotcrete as a support element interacting with the rock mass,mechanism of wet shotcrete interacting with rock in support systems was analyzed through theor... In order to have a good understanding of the behavior of wet shotcrete as a support element interacting with the rock mass,mechanism of wet shotcrete interacting with rock in support systems was analyzed through theoretical,numerical study and analytical analysis.A new model of distribution of rock stress state after wet shotcrete was applied,which includes shotcrete layer,composite layer,strengthening layer,plastic layer and elastic layer,and a full illustration of the rock mass stress state was given after shotcrete interacting with rock mass.At the same time,numerical analysis with FLAC gives a stress distribution along the monitor line,respectively,at the sidewall and roof of the tunnel.The displacement obviously decreases with the depth of rock,the tangential stress for tunnel supported by shotcrete is lower than that without shotcrete,and radial stress for tunnel supported by shotcrete is higher than that without shotcrete.It has been demonstrated by AIRY'S stress function,which gives a reasonable solution.Finally,the application of wet shotcrete in Jinfeng Gold Mine shows that the displacement of tunnel decreases obviously in sidewall and roof. 展开更多
关键词 wet shotcrete support systems MECHANISM SIMULATION distribution of stress
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Multi-agent decision support system for missile defense based on improved PSO algorithm 被引量:6
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作者 Zilong Cheng Li Fan Yulin Zhang 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2017年第3期514-525,共12页
Ballistic missile defense system (BMDS) is important for its special role in ensuring national security and maintaining strategic balance. Research on modeling and simulation of the BMDS beforehand is essential as dev... Ballistic missile defense system (BMDS) is important for its special role in ensuring national security and maintaining strategic balance. Research on modeling and simulation of the BMDS beforehand is essential as developing a real one requires lots of manpower and resources. BMDS is a typical complex system for its nonlinear, adaptive and uncertainty characteristics. The agent-based modeling method is well suited for the complex system whose overall behaviors are determined by interactions among individual elements. A multi-agent decision support system (DSS), which includes missile agent, radar agent and command center agent, is established based on the studies of structure and function of BMDS. Considering the constraints brought by radar, intercept missile, offensive missile and commander, the objective function of DSS is established. In order to dynamically generate the optimal interception plan, the variable neighborhood negative selection particle swarm optimization (VNNSPSO) algorithm is proposed to support the decision making of DSS. The proposed algorithm is compared with the standard PSO, constriction factor PSO (CFPSO), inertia weight linear decrease PSO (LDPSO), variable neighborhood PSO (VNPSO) algorithm from the aspects of convergence rate, iteration number, average fitness value and standard deviation. The simulation results verify the efficiency of the proposed algorithm. The multi-agent DSS is developed through the Repast simulation platform and the constructed DSS can generate intercept plans automatically and support three-dimensional dynamic display of missile defense process. 展开更多
关键词 agent-based modeling missile defense system decision support system (DSS) variable neighborhood negative selection particle swarm optimization (PSO)
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Detection of PERV by polymerase chain reaction and its safety in bioartificial liver support system 被引量:19
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作者 Hai-Hui Wang Ying-Jie Wang +4 位作者 Hong-Ling Liu Jun Liu Yan-Ping Huang Hai-Tao Guo Yu-Ming Wang 《World Journal of Gastroenterology》 SCIE CAS CSCD 2006年第8期1287-1291,共5页
AIM: To establish a method detecting porcine endogenous retrovirus (PERV) in China experimental minipigs and to evaluate the safety of PERV in three individuals treated with bioartificial liver support systems base... AIM: To establish a method detecting porcine endogenous retrovirus (PERV) in China experimental minipigs and to evaluate the safety of PERV in three individuals treated with bioartificial liver support systems based on porcine hepatocytes. METHODS: Porcine hepatocytes were isolated with two-stage perfusion method, then cultured in the bioreactor, which is separated by a semipermeable membrane (0.2μm) from the lumen through which the patients' blood plasma was circulated. After posthemoperfusion, patients' blood was obtained for screening. Additionally, samples of medium collected from both intraluminal and extraluminal compartments of the laboratory bioreactor and culture supernate in vitro was analyzed. The presence of viral sequences was estimated by polymerase chain reaction (PCR) and reverse transcriptase-polymerase chain reaction (RTPCR). Finally, the infection of virus in the supernate of common culture was ascertained by exposure to the fetal liver cells. RESULTS: PERV-specific gag sequences were found in the porcine hepatocytes using RT-PCR. and were detected in all samples from the intraluminal, extraluminal samples and culture supernate. However, culture supernatant from primary porcine hepatocytes (cleared of cellular debris) failed to infect human fetal liver cells. Finally, RT-PCR detected no PERV infection was found in the blood samples obtained from three patients at various times post-hemoperfusion. CONCLUSION: The assays used are specific and sensitive, identified by second PCR. PERVs could be released from hepatocytes cultured in bioreactor without the stimulation of mitogen and could not be prevented by the hollow fiber semipermeable membrane, indicating the existence of PERV safety in extracorporeal bioartificial liver support system (EBLSS). 展开更多
关键词 PERV Bioartificial liver support systems Polymerase chain reaction
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Development of a GIS-based Decision Support System for Assessing Land Use Status 被引量:6
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作者 Ryosuke Shibasaki Kanichiro Matsumura 《Geo-Spatial Information Science》 2004年第1期72-78,共7页
The objectives of this study are to assess land s ui tability and to predict the spatial and temporal changes in land use types (LUTs ) by using GIS-based land use management decision support system. A GIS databas e w... The objectives of this study are to assess land s ui tability and to predict the spatial and temporal changes in land use types (LUTs ) by using GIS-based land use management decision support system. A GIS databas e with data on climate, topography, soil characteristic, irrigation condition, f ertilizer application, and special socioeconomic activities has been developed a nd used for the evaluation of land productivity for different crops by integrati ng with a crop growth model-the erosion productivity impact calculator (EPIC). International food policy simulation model (IFPSIM) is also embedded into GIS fo r the predictions of how crop demands and crop market prices will change under a lternative policy scenarios. An inference engine (IE) including land use choice model is developed to illustrate land use choice behavior based on logit models , which allows to analyze how diversified factors ranging from climate changes, crop price changes to land management changes can affect the distribution of agr icultural land use. A test for integrated simulation is taken in each 0.1° by 0.1° grid cell to predict the change of agricultural land use types at globa l level. Global land use changes are simulated from 1992 to 2050. 展开更多
关键词 EPIC land use decision support system international trade model logitmodel
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