In the last decade, turbulent times and uncertainti es in the business environment have made ground for a new business era, and "chang e" has become a major characteristic of the new era. This has resulted i...In the last decade, turbulent times and uncertainti es in the business environment have made ground for a new business era, and "chang e" has become a major characteristic of the new era. This has resulted in tirele ss evolution of business systems and the creation of new manufacturing and manag ement philosophies. Agile Manufacturing (AM) is a step forward in generation of new means for better performance and success of business, and in practice is a s trategic approach to manufacturing by considering the new conditions of the business environment. This paper discusses the concepts and development of a met hodology to achieve agility in manufacturing organisations. Following an introdu ction of the subject of agility, a discussion of the methodology and practical t ools to support the implementation of the methodology, including metrics for the assessment of agility drivers, capability and performance are given. Aspects of the tools are tested in an aerospace company.展开更多
The Central Committee of the Communist Party of China and the State Council have put forward "the strategy for revitalizing China through science and education" and decided to implement it with the turn of t...The Central Committee of the Communist Party of China and the State Council have put forward "the strategy for revitalizing China through science and education" and decided to implement it with the turn of the century. All circles of the society and the broad masses of people i n China are unprecedentedly raising their scientific and technical awareness and so gradually reaching more and more common understanding of the role that fundamental research in natural science has been playing as a cornerstone in the implementation of "the strategy of revitalizing China through science and education".展开更多
The purpose of this research is to analyze the causal mechanisms of learning difficulties of middle school students and use them to propose strategies to help them.This research is particularly valuable for its focus ...The purpose of this research is to analyze the causal mechanisms of learning difficulties of middle school students and use them to propose strategies to help them.This research is particularly valuable for its focus on middle school students.Research on this critical transition period is often lacking compared to primary and high school.Therefore,this research establishes a structured equation model and analyzes the data from the survey using the partial least squares method.The data were obtained from a 13,900 Wenzhou City,China students’questionnaire.The research found that learning strategies were the most significant influences on learning effectiveness,followed by learning motivation and learning relationships.Meanwhile,learning relationships had a significant impact on learning pressure.Therefore,this research proposes targeted support strategies.It aims to enhance learning motivation(Set achievable learning goals for each student with learning difficulties based on their actual situation),optimize learning strategies(Encourage students with learning difficulties to learn self-regulatory strategies such as goal setting,time management,and self-reflection),and improve learning relationships(Establish a good social network to promote positive interaction between students with learning difficulties and their peers).At the same time,it reduces students’learning pressure.Ultimately,the learning effectiveness of students with learning difficulties is improved.展开更多
Neuronal regeneration in the peripheral nervous system arises via a synergistic interplay of neurotrophic factors,integrins,cytoskeletal proteins,mechanical cues,cytokines,stem cells,glial cells and astrocytes.
Hypoxia is a condition found commonly in several disorders,such as ischemia,asthma,anemia and neonatal hypoxia.Individuals subjected suddenly to high altitude or extreme exercise are also challenged to low oxygen（O2...Hypoxia is a condition found commonly in several disorders,such as ischemia,asthma,anemia and neonatal hypoxia.Individuals subjected suddenly to high altitude or extreme exercise are also challenged to low oxygen（O2）levels.Since the brain presents elevated basal O_2 consumption,this organ is readily affected by hypoxia.For this reason,展开更多
This paper presents an integrated investigation of the ground stability of a deep gateroad with a 1 km burial depth based on a field test, case studies, and numerical modelling. In situ stress measurements and mechani...This paper presents an integrated investigation of the ground stability of a deep gateroad with a 1 km burial depth based on a field test, case studies, and numerical modelling. In situ stress measurements and mechanical properties tests were first conducted in the test site. Then, the deformation behavior, stress and yield zone distributions, as well as the bolts load of the gateroad, were simulated using FLAC3D software. The model results demonstrated that the soft rock properties and high in situ stress were the main factors for the deep gateroad instability, and the shear slip failure induced by the high stress was the primary failure model for the deep rock mass. In addition, the unsuitable support patterns, especially the relatively short bolts/cables with low pre-tensions, the lack of high-strengthen secondary supports and the unsupported floor strata, also contributed to the gateroad instability. Subsequently, a new combined supporting strategy, incorporating longer bolts/cables, yielding ring supports, and grouting measures, was proposed for the deep gateroad, and its validity was verified via field monitoring. All these could be a reference for understanding the failure mechanism of the gateroad with 1 km burial depth.展开更多
Ceramic vat photopolymerization(VPP)enables the fabrication of complex components with excellent properties and high precision.However,compared with metals and polymers,the industrial application of ceramic VPPs remai...Ceramic vat photopolymerization(VPP)enables the fabrication of complex components with excellent properties and high precision.However,compared with metals and polymers,the industrial application of ceramic VPPs remains relatively limited.This can be attributed to the challenges associated with ceramic feedstock printability,the complexity of the printing process,insufficient performance evaluation,and service verification.To overcome these limitations,the design of a viscoelastic paste and corresponding VPP strategies offer a promising solution.This paper presents a review of the research on the state of viscoelastic ceramic paste-based VPP.The main tech-nical aspects,including the paste design,support strategies,green-body cleaning,and subsequent post-treatment,are discussed.Furthermore,representative applications of VPP for various types of advanced ceramics are sur-veyed.This review also highlights the technical challenges involved and provides suggestions for addressing these issues.Finally,future directions for promoting the additive manufacturing of advanced ceramic components with enhanced efficiency and reliability are discussed.展开更多
We report a novel P-directing effect of imidazolium based ionic liquid,which was observed when we conducted the glycosylation of a 6-O-acetyl-2,3,4-tri-O-benzyl-mannose trichloroacetimidate donor with a modified ionic...We report a novel P-directing effect of imidazolium based ionic liquid,which was observed when we conducted the glycosylation of a 6-O-acetyl-2,3,4-tri-O-benzyl-mannose trichloroacetimidate donor with a modified ionic liquid support acceptor. The mechanism was investigated and a hypothesis was proposed.After optimization of the reaction conditions,an innovative method for the selective construction of 1,2-cis-β-D-mannopyranosyl linkage was developed.展开更多
The topic investigated competition in marketing as a survival yardstick for small and medium enterprises （SMEs） in Nigeria. The objectives addressed by this study were： （1） identifying different types and intensi...The topic investigated competition in marketing as a survival yardstick for small and medium enterprises （SMEs） in Nigeria. The objectives addressed by this study were： （1） identifying different types and intensity of competition that SMEs are exposed to along the life-cycle portfolio in Nigeria; （2） quantifying the strength of SMEs vis-a-vis some foreign enterprises in terms of market competition; and （3） proffering solutions on how best they could match competitively these foreign enterprises. Relevant models and theories were employed in literature to evolve detailed analysis of issues relating to the variables used in terms of competition in marketing and survival of juice-producing SMEs. Two hypotheses were investigated through the survey of 20 prominent Ikeja based SMEs using Cluster sampling, 5-points Likert summated rating scale was adopted, while Yard＇s formula with 95% confidence level and 5% error tolerance was used. Alternative form validity of the instrument was measured at 0.63 while its reliability was measured at Cronbach＇s alpha of 0.70. Pearson＇s product-moment correlation was used in testing hypothesis 1 while standard multiple regressions were used to test hypothesis 2. Findings revealed that there was strong relationship between survival of juice-producing SMEs with forms of competition on a firm＇s life-cycle; while competition had positive effects on survival components for the enterprises. It was concluded that since competition subsists in any firm＇s life-cycle, strategies to support operations for survival must be adopted. It was recommended that operators of SMEs have to monitor and manage competition as it affects their businesses positively and/or negatively.展开更多
文摘In the last decade, turbulent times and uncertainti es in the business environment have made ground for a new business era, and "chang e" has become a major characteristic of the new era. This has resulted in tirele ss evolution of business systems and the creation of new manufacturing and manag ement philosophies. Agile Manufacturing (AM) is a step forward in generation of new means for better performance and success of business, and in practice is a s trategic approach to manufacturing by considering the new conditions of the business environment. This paper discusses the concepts and development of a met hodology to achieve agility in manufacturing organisations. Following an introdu ction of the subject of agility, a discussion of the methodology and practical t ools to support the implementation of the methodology, including metrics for the assessment of agility drivers, capability and performance are given. Aspects of the tools are tested in an aerospace company.
文摘The Central Committee of the Communist Party of China and the State Council have put forward "the strategy for revitalizing China through science and education" and decided to implement it with the turn of the century. All circles of the society and the broad masses of people i n China are unprecedentedly raising their scientific and technical awareness and so gradually reaching more and more common understanding of the role that fundamental research in natural science has been playing as a cornerstone in the implementation of "the strategy of revitalizing China through science and education".
基金2025 Wenzhou Key Research Base of Philosophy and Social Science(Wenzhou University Learning Science and Technology Research Centre)Research Project:Investigation and Strategy Research on the Causes of Middle School Students’Learning Difficulties in the Context of the Leading Country in Education.
文摘The purpose of this research is to analyze the causal mechanisms of learning difficulties of middle school students and use them to propose strategies to help them.This research is particularly valuable for its focus on middle school students.Research on this critical transition period is often lacking compared to primary and high school.Therefore,this research establishes a structured equation model and analyzes the data from the survey using the partial least squares method.The data were obtained from a 13,900 Wenzhou City,China students’questionnaire.The research found that learning strategies were the most significant influences on learning effectiveness,followed by learning motivation and learning relationships.Meanwhile,learning relationships had a significant impact on learning pressure.Therefore,this research proposes targeted support strategies.It aims to enhance learning motivation(Set achievable learning goals for each student with learning difficulties based on their actual situation),optimize learning strategies(Encourage students with learning difficulties to learn self-regulatory strategies such as goal setting,time management,and self-reflection),and improve learning relationships(Establish a good social network to promote positive interaction between students with learning difficulties and their peers).At the same time,it reduces students’learning pressure.Ultimately,the learning effectiveness of students with learning difficulties is improved.
基金CSIRO, the ARC and the NHMRC for providing funding that supported this work
文摘Neuronal regeneration in the peripheral nervous system arises via a synergistic interplay of neurotrophic factors,integrins,cytoskeletal proteins,mechanical cues,cytokines,stem cells,glial cells and astrocytes.
基金Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (CAPES)Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq)INCT-Excitoxicidade e Neuroprotecao and by FINEP research grant “Rede Instituto Brasileiro de Neurociencia (IBN-Net)” #01.06.0842-00
文摘Hypoxia is a condition found commonly in several disorders,such as ischemia,asthma,anemia and neonatal hypoxia.Individuals subjected suddenly to high altitude or extreme exercise are also challenged to low oxygen（O2）levels.Since the brain presents elevated basal O_2 consumption,this organ is readily affected by hypoxia.For this reason,
基金Project（2017RCJJ011） supported by the Scientific Research Foundation of Shaaadong University of Science and Technology for Recruited Talents, China Projects（01CK03203, 02CK02302） supported by the Shaaadong Provincial First-Class Discipline Fundamental, China Proj ect（ZR2018QEE001） supported by the Natural Science Foundation of Shandong Province, China
文摘This paper presents an integrated investigation of the ground stability of a deep gateroad with a 1 km burial depth based on a field test, case studies, and numerical modelling. In situ stress measurements and mechanical properties tests were first conducted in the test site. Then, the deformation behavior, stress and yield zone distributions, as well as the bolts load of the gateroad, were simulated using FLAC3D software. The model results demonstrated that the soft rock properties and high in situ stress were the main factors for the deep gateroad instability, and the shear slip failure induced by the high stress was the primary failure model for the deep rock mass. In addition, the unsuitable support patterns, especially the relatively short bolts/cables with low pre-tensions, the lack of high-strengthen secondary supports and the unsupported floor strata, also contributed to the gateroad instability. Subsequently, a new combined supporting strategy, incorporating longer bolts/cables, yielding ring supports, and grouting measures, was proposed for the deep gateroad, and its validity was verified via field monitoring. All these could be a reference for understanding the failure mechanism of the gateroad with 1 km burial depth.
基金supported by Suzhou Key Industrial Technology In-novation Projects of China(Grant Nos.SYG202040,SGC2021063)Open Fund Project of 3D Printing Equipment and Manufacturing Key Laboratory in Jiangsu Province of China(Grant.No.3DL202103).
文摘Ceramic vat photopolymerization(VPP)enables the fabrication of complex components with excellent properties and high precision.However,compared with metals and polymers,the industrial application of ceramic VPPs remains relatively limited.This can be attributed to the challenges associated with ceramic feedstock printability,the complexity of the printing process,insufficient performance evaluation,and service verification.To overcome these limitations,the design of a viscoelastic paste and corresponding VPP strategies offer a promising solution.This paper presents a review of the research on the state of viscoelastic ceramic paste-based VPP.The main tech-nical aspects,including the paste design,support strategies,green-body cleaning,and subsequent post-treatment,are discussed.Furthermore,representative applications of VPP for various types of advanced ceramics are sur-veyed.This review also highlights the technical challenges involved and provides suggestions for addressing these issues.Finally,future directions for promoting the additive manufacturing of advanced ceramic components with enhanced efficiency and reliability are discussed.
基金National Natural Science Foundation of China (Grant No.20732001) the State New Drug Innovation(the Ministry of Science and Technology of China,Grant No. 2009ZX09501-011)
文摘We report a novel P-directing effect of imidazolium based ionic liquid,which was observed when we conducted the glycosylation of a 6-O-acetyl-2,3,4-tri-O-benzyl-mannose trichloroacetimidate donor with a modified ionic liquid support acceptor. The mechanism was investigated and a hypothesis was proposed.After optimization of the reaction conditions,an innovative method for the selective construction of 1,2-cis-β-D-mannopyranosyl linkage was developed.
文摘The topic investigated competition in marketing as a survival yardstick for small and medium enterprises （SMEs） in Nigeria. The objectives addressed by this study were： （1） identifying different types and intensity of competition that SMEs are exposed to along the life-cycle portfolio in Nigeria; （2） quantifying the strength of SMEs vis-a-vis some foreign enterprises in terms of market competition; and （3） proffering solutions on how best they could match competitively these foreign enterprises. Relevant models and theories were employed in literature to evolve detailed analysis of issues relating to the variables used in terms of competition in marketing and survival of juice-producing SMEs. Two hypotheses were investigated through the survey of 20 prominent Ikeja based SMEs using Cluster sampling, 5-points Likert summated rating scale was adopted, while Yard＇s formula with 95% confidence level and 5% error tolerance was used. Alternative form validity of the instrument was measured at 0.63 while its reliability was measured at Cronbach＇s alpha of 0.70. Pearson＇s product-moment correlation was used in testing hypothesis 1 while standard multiple regressions were used to test hypothesis 2. Findings revealed that there was strong relationship between survival of juice-producing SMEs with forms of competition on a firm＇s life-cycle; while competition had positive effects on survival components for the enterprises. It was concluded that since competition subsists in any firm＇s life-cycle, strategies to support operations for survival must be adopted. It was recommended that operators of SMEs have to monitor and manage competition as it affects their businesses positively and/or negatively.
