The small and medium enterprise firms are renowned for improving the nation’s economy through the provision of job opportunities for its populace,improving the financial and investment status of the countries a...The small and medium enterprise firms are renowned for improving the nation’s economy through the provision of job opportunities for its populace,improving the financial and investment status of the countries and provision of innovative products that meets the need of the people.SMEs are key players in the economy,through sustainable development goals(SDGs)enabling them to thrive in the open business environment and actively applying the digital transformation,promoting inclusive and sustainable industrialization should be the core of any country government.This research is designed to explore the influence of government intervention and support on enterprise performance and growth in five business sectors-Hospitality,Education,Health care,Bottled Water Production and Transport and Logistics organizations.The research paper had a descriptive research design with a randomly selected sample size of one hundred and ninety-seven respondents.The research hypotheses were tested using(Factor Analysis and Ordinal Logistic Regression Analysis)with Statistical Packages for Social Science(SPSS)version 25.The results of the study reveal that government intervention policies and intervention programmes when instituted will promote the growth of business firms in Nigeria.Also identified are relevant recommendations that serve as motivation for policy administrators,entrepreneurs,and business managers to ensure that relevant intervention programme is adopted to boost performance and growth of the SME sector in Nigeria.展开更多
Exercise is established as a supportive care intervention during and after various cancer treatment modalities.1,2 Documented benefits include improvements in health-related fitness,physical functioning,some symptoms/...Exercise is established as a supportive care intervention during and after various cancer treatment modalities.1,2 Documented benefits include improvements in health-related fitness,physical functioning,some symptoms/side effects,psychosocial functioning,and quality of life.1,2 Exercise has not been established,however,as a treatment for any type of cancer in any clinical oncology setting.2 This special topic of the Journal of Sport and Health Science(JSHS)is dedicated to research on“Exercise as a cancer treatment”.The special topic sought preclinical,observational,or clinical studies examining the effects of exercise after a cancer diagnosis on a cancer outcome(e.g.,cell/tumor growth,tumor response,disease recurrence,progression,death from cancer).It includes 6 original articles and an invited opinion article.展开更多
Introduction:This study reports a confirmed case of human rabies diagnosed through metagenomic nextgeneration sequencing(mNGS).The patient was a 22-year-old female who developed symptoms 3 months after sustaining a sc...Introduction:This study reports a confirmed case of human rabies diagnosed through metagenomic nextgeneration sequencing(mNGS).The patient was a 22-year-old female who developed symptoms 3 months after sustaining a scratch on the upper lip from a domesticated dog,without receiving postexposure prophylaxis(PEP).She initially presented with urinary symptoms and was misdiagnosed with a urinary tract infection.Neurological symptoms subsequently emerged,prompting intensive life support interventions including mechanical ventilation,recombinant human interferon-α2b,ribavirin,norepinephrine,venoarterial extracorporeal membrane oxygenation(VAECMO),and continuous renal replacement therapy.Methods:Clinical data were collected from hospital records,including exposure history,symptoms,treatments,and outcomes.Saliva specimens were tested by reverse transcription polymerase chain reaction(RTPCR)and mNGS.Sequencing data were processed by standard bioinformatics pipelines,and phylogenetic analysis was performed with MAFFT alignment and IQ-TREE maximum-likelihood reconstruction.Results:Rabies virus infection was confirmed through reverse transcription polymerase chain reaction(RTPCR)and mNGS analysis of saliva samples.The detected strain,JSTZ190314,represents the first documented case of this genotype in Guangxi,China.Despite initial stabilization with ECMO support,the patient’s neurological condition deteriorated progressively,leading to brain death 28 days after neurological onset(34 days from initial urinary symptoms).Conclusion:mNGS proves invaluable as a diagnostic tool for atypical rabies presentations.Enhancing early clinical recognition capabilities,ensuring timely and standardized PEP implementation,and strengthening regional viral strain surveillance represent critical components for effective rabies prevention and control strategies.展开更多
文摘The small and medium enterprise firms are renowned for improving the nation’s economy through the provision of job opportunities for its populace,improving the financial and investment status of the countries and provision of innovative products that meets the need of the people.SMEs are key players in the economy,through sustainable development goals(SDGs)enabling them to thrive in the open business environment and actively applying the digital transformation,promoting inclusive and sustainable industrialization should be the core of any country government.This research is designed to explore the influence of government intervention and support on enterprise performance and growth in five business sectors-Hospitality,Education,Health care,Bottled Water Production and Transport and Logistics organizations.The research paper had a descriptive research design with a randomly selected sample size of one hundred and ninety-seven respondents.The research hypotheses were tested using(Factor Analysis and Ordinal Logistic Regression Analysis)with Statistical Packages for Social Science(SPSS)version 25.The results of the study reveal that government intervention policies and intervention programmes when instituted will promote the growth of business firms in Nigeria.Also identified are relevant recommendations that serve as motivation for policy administrators,entrepreneurs,and business managers to ensure that relevant intervention programme is adopted to boost performance and growth of the SME sector in Nigeria.
基金supported by the Canada Research Chairs Programa Foundation Grant from the Canadian Institutes of Health Research (No. 159927)
文摘Exercise is established as a supportive care intervention during and after various cancer treatment modalities.1,2 Documented benefits include improvements in health-related fitness,physical functioning,some symptoms/side effects,psychosocial functioning,and quality of life.1,2 Exercise has not been established,however,as a treatment for any type of cancer in any clinical oncology setting.2 This special topic of the Journal of Sport and Health Science(JSHS)is dedicated to research on“Exercise as a cancer treatment”.The special topic sought preclinical,observational,or clinical studies examining the effects of exercise after a cancer diagnosis on a cancer outcome(e.g.,cell/tumor growth,tumor response,disease recurrence,progression,death from cancer).It includes 6 original articles and an invited opinion article.
基金Supported by the Specific Research Project of Guangxi for Research Bases and Talents(AD22035052).
文摘Introduction:This study reports a confirmed case of human rabies diagnosed through metagenomic nextgeneration sequencing(mNGS).The patient was a 22-year-old female who developed symptoms 3 months after sustaining a scratch on the upper lip from a domesticated dog,without receiving postexposure prophylaxis(PEP).She initially presented with urinary symptoms and was misdiagnosed with a urinary tract infection.Neurological symptoms subsequently emerged,prompting intensive life support interventions including mechanical ventilation,recombinant human interferon-α2b,ribavirin,norepinephrine,venoarterial extracorporeal membrane oxygenation(VAECMO),and continuous renal replacement therapy.Methods:Clinical data were collected from hospital records,including exposure history,symptoms,treatments,and outcomes.Saliva specimens were tested by reverse transcription polymerase chain reaction(RTPCR)and mNGS.Sequencing data were processed by standard bioinformatics pipelines,and phylogenetic analysis was performed with MAFFT alignment and IQ-TREE maximum-likelihood reconstruction.Results:Rabies virus infection was confirmed through reverse transcription polymerase chain reaction(RTPCR)and mNGS analysis of saliva samples.The detected strain,JSTZ190314,represents the first documented case of this genotype in Guangxi,China.Despite initial stabilization with ECMO support,the patient’s neurological condition deteriorated progressively,leading to brain death 28 days after neurological onset(34 days from initial urinary symptoms).Conclusion:mNGS proves invaluable as a diagnostic tool for atypical rabies presentations.Enhancing early clinical recognition capabilities,ensuring timely and standardized PEP implementation,and strengthening regional viral strain surveillance represent critical components for effective rabies prevention and control strategies.
