Immobilizing chiral 1,1＇-bi-2-naphthol （BINOL） in one step onto polymer backbone via stable carbon-carbon bond through Suzuki reaction was achieved. The application of this immobilized chiral BINOL to the catalytic...Immobilizing chiral 1,1＇-bi-2-naphthol （BINOL） in one step onto polymer backbone via stable carbon-carbon bond through Suzuki reaction was achieved. The application of this immobilized chiral BINOL to the catalytic asymmetric oxidation of sulfide to sulfoxide exhibited good activity （up to 60% yield） and high enantioselectivity （up to 89% ee）. The immobilized chiral catalyst was very stable and could be readily reused for over 5 times without significant loss of catalytic activity and enantioselectivity.展开更多
Bentonite is a necessary binder in producing pellets.Its excessive use reduces the iron grade of pellets and increases production costs.Minimizing bentonite dosage is essential for producing high-quality iron ore pell...Bentonite is a necessary binder in producing pellets.Its excessive use reduces the iron grade of pellets and increases production costs.Minimizing bentonite dosage is essential for producing high-quality iron ore pellets.Addressing the gap in the application of organically-intercalated modified bentonite in the pelletizing field,this study introduces an innovative modification process for bentonite that employs the synergistic effect of mechanical force and dimethyl sulfoxide to enhance the intercalation of organic compounds within bentonite,thus significantly enhancing its binding performance.The colloid value and swell capacity of modified bentonite(98.5 m L/3g and 55.0 m L/g)were much higher than the original bentonite(90.5 m L/3g and 17.5 m L/g).With the decrease of bentonite dosage from1.5wt%to 1.0wt%,the drop number of green pellets from a height of 0.5 m and the compressive strengths of roasted pellets using the modified bentonite(6.0 times and 2916 N per pellet)were significantly higher than those of the original bentonite(4.0 times and 2739 N per pellet).This study provides a comprehensive analysis of the intercalation modification mechanism of bentonite,offering crucial technical insights for the development of high-performance modified bentonite as iron ore pellet binders.展开更多
Osteochondral allografting has been proved to be a useful method to treat diseased or damaged areas of joint surfaces. Operational long-term stocks of grafts which supply a buffer between procurement and utilization w...Osteochondral allografting has been proved to be a useful method to treat diseased or damaged areas of joint surfaces. Operational long-term stocks of grafts which supply a buffer between procurement and utilization would contribute to the commercialization or industrialization of this technology. Vitrification has been thought to be a promising method for successful preservation of articular cartilage （AC）, but high concentration cryoprotectants （CPAs） are used which may cause high cellular toxicity. An effective way to reduce CPA toxioity is to increase CPA concen- tration gradually while the temperature is lowered. Understanding the mechanism of （31~A permeation at subzero temperatures is important for designing the cryopreservation protocol. In this research, the permeation of dimethyl sulfoxide （MezSO） in ovine AC at subzero temperatures was studied experimentally. Pretreated AC discs were ex- posed in Me2SO solutions for different time （0, 5, 15, 30, 50, 80, and 120 min） at three temperature levels （-10, -20, and -30℃）. The Me2SO concentration within the tissue was determined by ultraviolet （UV） spectrophotometry. The diffusion coefficients were estimated to be 0.85×10-6, 0.48×10-8, and 0.27×10-6 cm2/s at -10, -20, and -,30℃, respectively, and the corresponding activation energy was 29.23 kJ/mol. Numerical simulation was performed to com- pare two Me2SO addition protocols, and the results demonstrated that the total loading duration could be effectively reduced with the knowledge of permeation kinetics.展开更多
AIM: To investigate whether dimethyl sulfoxide(DMSO) inhibits gut inflammation and barrier dysfunction following zymosan-induced systemic inflammatoryresponse syndrome and multiple organ dysfunction syndrome.METHODS: ...AIM: To investigate whether dimethyl sulfoxide(DMSO) inhibits gut inflammation and barrier dysfunction following zymosan-induced systemic inflammatoryresponse syndrome and multiple organ dysfunction syndrome.METHODS: Sprague-Dawley rats were randomly divided into four groups: sham with administration of normal saline(SS group); sham with administration of DMSO(SD group); zymosan with administration of normal saline(ZS group); and zymosan with administration of DMSO(ZD group). Each group contained three subgroups according to 4 h,8 h,and 24 h after surgery. At 4 h,8 h,and 24 h after intraperitoneal injection of zymosan(750 mg/kg),the levels of intestinal inflammatory cytokines [tumor necrosis factor-alpha(TNF-α) and interleukin(IL)-10] and oxides(myeloperoxidase,malonaldehyde,and superoxide dismutase) were examined. The levels of diamine oxidase(DAO) in plasma and intestinal mucosal blood flow(IMBF) were determined. Intestinal injury was also evaluated using an intestinal histological score and apoptosis of intestinal epithelial cells was determined by deoxynucleotidyl transferase d UTP nick end labeling(TUNEL) assay. The intestinal epithelial tight junction protein,ZO-1,was observed by immunofluorescence.RESULTS: DMSO decreased TNF-α and increased IL-10 levels in the intestine compared with the ZS group at the corresponding time points. The activity of intestinal myeloperoxidase in the ZS group was higher than that in the ZD group 24 h after zymosan administration(P < 0.05). DMSO decreased the content of malondialdehyde(MDA) and increased the activity of superoxide dehydrogenase(SOD) 24 h after zymosan administration. The IMBF was lowest at 24 h and was 49.34% and 58.26% in the ZS group and ZD group,respectively(P < 0.05). DMSO alleviated injury in intestinal villi,and the gut injury score was significantly lower than the ZS group(3.6 ± 0.2 vs 4.2 ± 0.3,P < 0.05). DMSO decreased the level of DAO in plasma compared with the ZS group(65.1 ± 4.7 U/L vs 81.1 ± 5.0 U/L,P < 0.05). DMSO significantly preserved ZO-1 protein expression and localization 24 h after zymosan administration. The TUNEL analysis indicated that the number of apoptotic intestinal cells in the ZS group was much higher than the ZD group(P < 0.05).CONCLUSION: DMSO inhibited intestinal cytokines and protected against zymosan-induced gut barrier dysfunction.展开更多
Phenylcarboxymethyl Sulfoxide, PhSOCH 2COOH(LH), complexes of six lanthanide nitrates: Ln 2L 2(NO 3) 4·2LH· n H 2O(where Ln=La, Ce, Pr, Nd, Sm, Eu) were synthesized. Elemental analyses, molar conduc...Phenylcarboxymethyl Sulfoxide, PhSOCH 2COOH(LH), complexes of six lanthanide nitrates: Ln 2L 2(NO 3) 4·2LH· n H 2O(where Ln=La, Ce, Pr, Nd, Sm, Eu) were synthesized. Elemental analyses, molar conductivities, IR, 1HNMR and TG DTA measurements were used to characterize the complexes. The results show that the ligand(L) is coordinated to metal ions through two oxygen atoms of the carboxyl group and one oxygen atom of the sulfoxide moieties. Neutral ligang (LH)is coordinated to two metal ions through two oxygen atoms of carboxyl group as an asymmetrical bridging bidentate. The fluorescence spectra of Eu 3+ complex indicates that there is no inversion symmetry at the site of Eu 3+ ion, but the emission intensity of fluorescence is quite good.The solubility of the complexes is very good in water.展开更多
Platinum, palladium and rhodium of the raw feeds extracted and separated with a new sulfoxide extractant （MSO） were studied in the paper. The pilot test results showed that the percentage extractions are more than 9...Platinum, palladium and rhodium of the raw feeds extracted and separated with a new sulfoxide extractant （MSO） were studied in the paper. The pilot test results showed that the percentage extractions are more than 99% for platinum and palladium in Pt-Pd feed, and the percentage strippings are 100% and 99.2% with HCl and ammonia, respectively. The ratio of palladium to platinum is 0.0016 in stripping platinum solution, and the ratio of platinum to palladium is 0.0020 in stripping palladium solution. The percentage extraction of platinum is 99% in Pt-Rh feed, and the percentage stripping is 100%. The ratio of rhodium to platinum is 0.0002 in stripping platinum solution. Therefore, platinum, palladium, and rhodium feeds are separated effectively with MSO.展开更多
DBUH-Br_3 catalyzed selective conversion of sulfides to sulfoxides in the presence of H_2O_2 as oxidizing agent is described.The reaction was performed selectively at room temperature and relatively short reaction times.
Two ternary complexes of RE(ClO_4)_3-DPSO-phen and two binary complexes of RE(ClO_4)_3-phen have been synthesized (RE=Eu, Tb; DPSO=diphenyl sulfoxide, phen=1,10-phenanthroline). Elemental analysis and TG-DTA studies s...Two ternary complexes of RE(ClO_4)_3-DPSO-phen and two binary complexes of RE(ClO_4)_3-phen have been synthesized (RE=Eu, Tb; DPSO=diphenyl sulfoxide, phen=1,10-phenanthroline). Elemental analysis and TG-DTA studies suggest that the ternary complexes consist of RE(ClO_4)_3(DPSO)(phen)_3·nH_2O (n=1, 3) and binary complexes consist of RE(phen)_4(ClO_4)_3. IR spectra studies indicate that the DPSO ligand is bonded with RE(Ⅲ) through oxygen atom in sulfinyl group and phen ligand is bonded to RE(Ⅲ) through nitrogen atom. The molar conductivities measured in the acetonitrile solution indicate that two inorganic anions ClO_4^- are coordinated and binary complexes are nonelectrolyte. In the fluorescent spectra it was found that the fluorescence emission intensity of the ternary complexes more intensive than that of the binary complexes.展开更多
The composition and structure of cyclic sulfoxide derivative Pd(IT) complexwere investigated. The coordinated number was studied with slope method. The coordination number is2 in lower acidity, but it is 3 in higher a...The composition and structure of cyclic sulfoxide derivative Pd(IT) complexwere investigated. The coordinated number was studied with slope method. The coordination number is2 in lower acidity, but it is 3 in higher acidity. Four methods, UV (ultraviolet) spectra, FUR(Fourier transform infrared) spectra, ~1H-NMR (nuclear magnetic resonance) spectra, and ^(13)C-NMRspectra, were used to determine the coordinated atom in complex. Pd is coordinated with O and S atomin S=O group in lower acidity media. The conversion of coordination bond appears with an increasingtime. Pd is coordinated with S atom in S=O group in higher acidity media, and inter-ligand-transferreaction occurs.展开更多
The recent development of selective oxidation of aromatic sulfides with molecular oxygen was highlighted.The sulfoxides and sulfones could be obtained by simply switching the reaction media,i.e.,bis(2-butoxyethyl)ethe...The recent development of selective oxidation of aromatic sulfides with molecular oxygen was highlighted.The sulfoxides and sulfones could be obtained by simply switching the reaction media,i.e.,bis(2-butoxyethyl)ether(BBE)or poly(ethylene glycol)dimethyl ether(PEGDME).The application of the high-boiling-point polyether as an initiator and green media can eliminate the need of large quantities of additives and volatile solvents.This strategy represents an economic and eco-friendly method that could find potential applications.展开更多
Synthesis of symmetrical diaryl sulfoxides from arenes and thionyl chloride in the presence of a catalytic amount of iodine at room temperature under solvent-free conditions is described. Mild reaction conditions, eas...Synthesis of symmetrical diaryl sulfoxides from arenes and thionyl chloride in the presence of a catalytic amount of iodine at room temperature under solvent-free conditions is described. Mild reaction conditions, easy workup, high yield, and easily available catalyst are important features of this method.展开更多
Poly（4-vinylpyridinium tribromide） was prepared from poly（4-vinylpyridin） and used for the selective oxidation of a variety of sulfides to the corresponding sulfoxides. The oxidation reaction was carried out heter...Poly（4-vinylpyridinium tribromide） was prepared from poly（4-vinylpyridin） and used for the selective oxidation of a variety of sulfides to the corresponding sulfoxides. The oxidation reaction was carried out heterogeneously in acetone/water, as green solvent, at room temperature.展开更多
文摘Immobilizing chiral 1,1＇-bi-2-naphthol （BINOL） in one step onto polymer backbone via stable carbon-carbon bond through Suzuki reaction was achieved. The application of this immobilized chiral BINOL to the catalytic asymmetric oxidation of sulfide to sulfoxide exhibited good activity （up to 60% yield） and high enantioselectivity （up to 89% ee）. The immobilized chiral catalyst was very stable and could be readily reused for over 5 times without significant loss of catalytic activity and enantioselectivity.
基金financial support by the National Key Research and Development Program of China(No.2023YFC2907801)the Hunan Provincial Natural Science Foundation of China(No.2023JJ40760)the Scientific and Technological Project of Yunnan Precious Metals Laboratory,China(No.YPML-2023050276)。
文摘Bentonite is a necessary binder in producing pellets.Its excessive use reduces the iron grade of pellets and increases production costs.Minimizing bentonite dosage is essential for producing high-quality iron ore pellets.Addressing the gap in the application of organically-intercalated modified bentonite in the pelletizing field,this study introduces an innovative modification process for bentonite that employs the synergistic effect of mechanical force and dimethyl sulfoxide to enhance the intercalation of organic compounds within bentonite,thus significantly enhancing its binding performance.The colloid value and swell capacity of modified bentonite(98.5 m L/3g and 55.0 m L/g)were much higher than the original bentonite(90.5 m L/3g and 17.5 m L/g).With the decrease of bentonite dosage from1.5wt%to 1.0wt%,the drop number of green pellets from a height of 0.5 m and the compressive strengths of roasted pellets using the modified bentonite(6.0 times and 2916 N per pellet)were significantly higher than those of the original bentonite(4.0 times and 2739 N per pellet).This study provides a comprehensive analysis of the intercalation modification mechanism of bentonite,offering crucial technical insights for the development of high-performance modified bentonite as iron ore pellet binders.
基金supported by the National Natural Science Foundation of China (No. 50606032)the Graduate Innovation Research Program of Zhejiang Province (No. YK2008020), China
文摘Osteochondral allografting has been proved to be a useful method to treat diseased or damaged areas of joint surfaces. Operational long-term stocks of grafts which supply a buffer between procurement and utilization would contribute to the commercialization or industrialization of this technology. Vitrification has been thought to be a promising method for successful preservation of articular cartilage （AC）, but high concentration cryoprotectants （CPAs） are used which may cause high cellular toxicity. An effective way to reduce CPA toxioity is to increase CPA concen- tration gradually while the temperature is lowered. Understanding the mechanism of （31~A permeation at subzero temperatures is important for designing the cryopreservation protocol. In this research, the permeation of dimethyl sulfoxide （MezSO） in ovine AC at subzero temperatures was studied experimentally. Pretreated AC discs were ex- posed in Me2SO solutions for different time （0, 5, 15, 30, 50, 80, and 120 min） at three temperature levels （-10, -20, and -30℃）. The Me2SO concentration within the tissue was determined by ultraviolet （UV） spectrophotometry. The diffusion coefficients were estimated to be 0.85×10-6, 0.48×10-8, and 0.27×10-6 cm2/s at -10, -20, and -,30℃, respectively, and the corresponding activation energy was 29.23 kJ/mol. Numerical simulation was performed to com- pare two Me2SO addition protocols, and the results demonstrated that the total loading duration could be effectively reduced with the knowledge of permeation kinetics.
基金Supported by National 11th Five-Year Plan of China for Military Medical Projects,No.06Z055the National Natural Science Foundation of China,No.81301607
文摘AIM: To investigate whether dimethyl sulfoxide(DMSO) inhibits gut inflammation and barrier dysfunction following zymosan-induced systemic inflammatoryresponse syndrome and multiple organ dysfunction syndrome.METHODS: Sprague-Dawley rats were randomly divided into four groups: sham with administration of normal saline(SS group); sham with administration of DMSO(SD group); zymosan with administration of normal saline(ZS group); and zymosan with administration of DMSO(ZD group). Each group contained three subgroups according to 4 h,8 h,and 24 h after surgery. At 4 h,8 h,and 24 h after intraperitoneal injection of zymosan(750 mg/kg),the levels of intestinal inflammatory cytokines [tumor necrosis factor-alpha(TNF-α) and interleukin(IL)-10] and oxides(myeloperoxidase,malonaldehyde,and superoxide dismutase) were examined. The levels of diamine oxidase(DAO) in plasma and intestinal mucosal blood flow(IMBF) were determined. Intestinal injury was also evaluated using an intestinal histological score and apoptosis of intestinal epithelial cells was determined by deoxynucleotidyl transferase d UTP nick end labeling(TUNEL) assay. The intestinal epithelial tight junction protein,ZO-1,was observed by immunofluorescence.RESULTS: DMSO decreased TNF-α and increased IL-10 levels in the intestine compared with the ZS group at the corresponding time points. The activity of intestinal myeloperoxidase in the ZS group was higher than that in the ZD group 24 h after zymosan administration(P < 0.05). DMSO decreased the content of malondialdehyde(MDA) and increased the activity of superoxide dehydrogenase(SOD) 24 h after zymosan administration. The IMBF was lowest at 24 h and was 49.34% and 58.26% in the ZS group and ZD group,respectively(P < 0.05). DMSO alleviated injury in intestinal villi,and the gut injury score was significantly lower than the ZS group(3.6 ± 0.2 vs 4.2 ± 0.3,P < 0.05). DMSO decreased the level of DAO in plasma compared with the ZS group(65.1 ± 4.7 U/L vs 81.1 ± 5.0 U/L,P < 0.05). DMSO significantly preserved ZO-1 protein expression and localization 24 h after zymosan administration. The TUNEL analysis indicated that the number of apoptotic intestinal cells in the ZS group was much higher than the ZD group(P < 0.05).CONCLUSION: DMSO inhibited intestinal cytokines and protected against zymosan-induced gut barrier dysfunction.
文摘Phenylcarboxymethyl Sulfoxide, PhSOCH 2COOH(LH), complexes of six lanthanide nitrates: Ln 2L 2(NO 3) 4·2LH· n H 2O(where Ln=La, Ce, Pr, Nd, Sm, Eu) were synthesized. Elemental analyses, molar conductivities, IR, 1HNMR and TG DTA measurements were used to characterize the complexes. The results show that the ligand(L) is coordinated to metal ions through two oxygen atoms of the carboxyl group and one oxygen atom of the sulfoxide moieties. Neutral ligang (LH)is coordinated to two metal ions through two oxygen atoms of carboxyl group as an asymmetrical bridging bidentate. The fluorescence spectra of Eu 3+ complex indicates that there is no inversion symmetry at the site of Eu 3+ ion, but the emission intensity of fluorescence is quite good.The solubility of the complexes is very good in water.
文摘Platinum, palladium and rhodium of the raw feeds extracted and separated with a new sulfoxide extractant （MSO） were studied in the paper. The pilot test results showed that the percentage extractions are more than 99% for platinum and palladium in Pt-Pd feed, and the percentage strippings are 100% and 99.2% with HCl and ammonia, respectively. The ratio of palladium to platinum is 0.0016 in stripping platinum solution, and the ratio of platinum to palladium is 0.0020 in stripping palladium solution. The percentage extraction of platinum is 99% in Pt-Rh feed, and the percentage stripping is 100%. The ratio of rhodium to platinum is 0.0002 in stripping platinum solution. Therefore, platinum, palladium, and rhodium feeds are separated effectively with MSO.
文摘DBUH-Br_3 catalyzed selective conversion of sulfides to sulfoxides in the presence of H_2O_2 as oxidizing agent is described.The reaction was performed selectively at room temperature and relatively short reaction times.
文摘Two ternary complexes of RE(ClO_4)_3-DPSO-phen and two binary complexes of RE(ClO_4)_3-phen have been synthesized (RE=Eu, Tb; DPSO=diphenyl sulfoxide, phen=1,10-phenanthroline). Elemental analysis and TG-DTA studies suggest that the ternary complexes consist of RE(ClO_4)_3(DPSO)(phen)_3·nH_2O (n=1, 3) and binary complexes consist of RE(phen)_4(ClO_4)_3. IR spectra studies indicate that the DPSO ligand is bonded with RE(Ⅲ) through oxygen atom in sulfinyl group and phen ligand is bonded to RE(Ⅲ) through nitrogen atom. The molar conductivities measured in the acetonitrile solution indicate that two inorganic anions ClO_4^- are coordinated and binary complexes are nonelectrolyte. In the fluorescent spectra it was found that the fluorescence emission intensity of the ternary complexes more intensive than that of the binary complexes.
文摘The composition and structure of cyclic sulfoxide derivative Pd(IT) complexwere investigated. The coordinated number was studied with slope method. The coordination number is2 in lower acidity, but it is 3 in higher acidity. Four methods, UV (ultraviolet) spectra, FUR(Fourier transform infrared) spectra, ~1H-NMR (nuclear magnetic resonance) spectra, and ^(13)C-NMRspectra, were used to determine the coordinated atom in complex. Pd is coordinated with O and S atomin S=O group in lower acidity media. The conversion of coordination bond appears with an increasingtime. Pd is coordinated with S atom in S=O group in higher acidity media, and inter-ligand-transferreaction occurs.
文摘The recent development of selective oxidation of aromatic sulfides with molecular oxygen was highlighted.The sulfoxides and sulfones could be obtained by simply switching the reaction media,i.e.,bis(2-butoxyethyl)ether(BBE)or poly(ethylene glycol)dimethyl ether(PEGDME).The application of the high-boiling-point polyether as an initiator and green media can eliminate the need of large quantities of additives and volatile solvents.This strategy represents an economic and eco-friendly method that could find potential applications.
文摘Synthesis of symmetrical diaryl sulfoxides from arenes and thionyl chloride in the presence of a catalytic amount of iodine at room temperature under solvent-free conditions is described. Mild reaction conditions, easy workup, high yield, and easily available catalyst are important features of this method.
基金Financial support for this work by the Ilam University,Ilam,Iran is gratefully acknowledged
文摘Poly（4-vinylpyridinium tribromide） was prepared from poly（4-vinylpyridin） and used for the selective oxidation of a variety of sulfides to the corresponding sulfoxides. The oxidation reaction was carried out heterogeneously in acetone/water, as green solvent, at room temperature.
