Dear Editor,Recent studies have emphasized the importance of editing cis-regulatory elements rather than protein-coding regions to subtly adjust plant traits(Rodrıguez-Leal et al.,2017).However,targeting cis-regulator...Dear Editor,Recent studies have emphasized the importance of editing cis-regulatory elements rather than protein-coding regions to subtly adjust plant traits(Rodrıguez-Leal et al.,2017).However,targeting cis-regulatory elements for mild phenotypic changes has been challenging,often failing to yield significant phenotypic change(Kwon et al.,2020).This underscores the necessity for innovative approaches to secure subtle phenotypic variations.Given the prevalence of gene duplication and redundancy in plant evolution,whereby multiple genes across different families may control a single function(Rodriguez-Leal et al.,2019),our approach involves editing several redundant genes within a family to precisely customize plant traits.展开更多
基金funded by the National Research Foundation of Korea(NRF)grants fromthe Ministry of Science and ICT(MSIT),Republic of Korea(2022R1C1C1002941 and RS-2024-00407469 to C.-T.K.,2020R1A2C1101915 to S.J.P.,2020R1A2C1004273 to RS-2023-00217064 to W.-J.H.).
文摘Dear Editor,Recent studies have emphasized the importance of editing cis-regulatory elements rather than protein-coding regions to subtly adjust plant traits(Rodrıguez-Leal et al.,2017).However,targeting cis-regulatory elements for mild phenotypic changes has been challenging,often failing to yield significant phenotypic change(Kwon et al.,2020).This underscores the necessity for innovative approaches to secure subtle phenotypic variations.Given the prevalence of gene duplication and redundancy in plant evolution,whereby multiple genes across different families may control a single function(Rodriguez-Leal et al.,2019),our approach involves editing several redundant genes within a family to precisely customize plant traits.
