Elevated translaminar cribrosa pressure difference(TLCPD),namely the difference between intraocular pressure(IOP)and intracranial pressure(ICP),has been widely accepted as an essential pathogenic factor in glaucomatou...Elevated translaminar cribrosa pressure difference(TLCPD),namely the difference between intraocular pressure(IOP)and intracranial pressure(ICP),has been widely accepted as an essential pathogenic factor in glaucomatous neurodegeneration,especially in normal-tension glaucoma(NTG).In 2010,Ningli Wang's team first identified that nearly half of NTG patients exhibit relatively low ICP through a prospective clinical study,opening a novel avenue of TLCPD-related pathophysiological mechanisms in glaucoma(Ren et al.,2010).展开更多
基金supported by the National Natural Science Foundation of China(82130029,82401256).
文摘Elevated translaminar cribrosa pressure difference(TLCPD),namely the difference between intraocular pressure(IOP)and intracranial pressure(ICP),has been widely accepted as an essential pathogenic factor in glaucomatous neurodegeneration,especially in normal-tension glaucoma(NTG).In 2010,Ningli Wang's team first identified that nearly half of NTG patients exhibit relatively low ICP through a prospective clinical study,opening a novel avenue of TLCPD-related pathophysiological mechanisms in glaucoma(Ren et al.,2010).
