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Bulk RNA sequencing combined with single-cell RNA sequencing analysis revealed the ferroptosis immune target of osteoarthritis synovial fibroblasts
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作者 Qian Wu Liang Zhou +1 位作者 Yuan Xue Jiaqian Wang 《Genes & Diseases》 2025年第6期19-21,共3页
Osteoarthritis(OA)is the most common joint disease in elderly patients.Its main pathological change is articular cartilage degeneration,accompanied by synovial inflammation and changes in subchondral bone structure,re... Osteoarthritis(OA)is the most common joint disease in elderly patients.Its main pathological change is articular cartilage degeneration,accompanied by synovial inflammation and changes in subchondral bone structure,resulting in pain and limited mobility.However,previous studies on OA mainly focused on the dysfunction of cartilage and chondrocytes,and the synovium and other joint structures have not received enough attention. 展开更多
关键词 synovial inflammation single cell rna sequencing OSTEOARTHRITIS ferroptosis articular cartilage degenerationaccompanied changes subchondral bone structureresulting synovial fibroblasts bulk rna sequencing
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