A morphologically structured model is proposed to describe the batch fermentation of lovastatin according to the growth kinetics of filamentous microorganisms. Three kinds of hyphae are considered in the model: active...A morphologically structured model is proposed to describe the batch fermentation of lovastatin according to the growth kinetics of filamentous microorganisms. Three kinds of hyphae are considered in the model: actively growing hyphae, non-growing hyphae and deactivated hyphae. Furthermore, actively growing hyphae consist of three morphological compartments: apical compartment which gives rise to hyphal tip extension; subapical compartment which is related to hyphal branching; and hyphal compartment which is only responsible for secondary metabolite formation. The kinetics of mycelial growth mechanism is summarized and applied in modeling lovastatin fermentation. A Michaelis-Menten kinetic model with substrate inhibition is proposed for product formation. As expected, the model simulations fit well with experimental data obtained either from a laboratory scale 10L fer-menter or from a pilot-plant scale fermenter.展开更多
The growth of filamentous microorganism is contributed by tip extension and branching. The microscopic growth of filamentous microorganism means the growth process from one or a few spores. In order to describe the mi...The growth of filamentous microorganism is contributed by tip extension and branching. The microscopic growth of filamentous microorganism means the growth process from one or a few spores. In order to describe the microscopic process, a population morphologically structured model is proposed, in which three morphological compartment and their interactions were considered, and the heterogeneity of hyphal growth was included. The model was applied to describe the microscopic growth of Streptomyces tendae and Geotrichum candidum with good agreement. From model prediction, it is concluded that if the number of hyphae is large enough (macroscopic growth), the specific growth rate of filamentous microorganism and the ratio of morphological forms in hyphae will become constant.展开更多
Objectives:Teachers are facing unprecedented new challenges leading them to face an increasing number of tasks that are not part of their job,as well as having to cope with the additional skills acquisition that comes...Objectives:Teachers are facing unprecedented new challenges leading them to face an increasing number of tasks that are not part of their job,as well as having to cope with the additional skills acquisition that comes with non-traditional forms of teaching and learning,and increased work pressure leading to an increase in the rate of teachers leaving the profession.Therefore,this study aims to explore the mechanism of the career calling on job burnout through career adaptability and work engagement.Methods:This study conducted a cross-sectional survey of 465 primary and secondary school teachers(PSST)in China's Mainland from the perspective of work adjustment and used structural equation modeling(SEM)to examine the mediating roles of career adaptability and work engagement in the relationship between teachers’career calling and job burnout.Results:The results show that PSSTs are above average in career calling,career adaptability,and work engagement,while job burnout is below average.A significant positive or negative correlation exists between career calling,career adaptability,work engagement,and job burnout.The result of path analysis indicates that career adaptability and work engagement exert an indirect influence on the job burnout of PSST through three paths:namely,the independent intermediary role of career adaptability(EV=−0.144),the independent intermediary role of work engagement(EV=0.172)and the chain intermediary role of the two(EV=0.176).Conclusion:This study emphasizes the importance of career adaptability and work engagement in teacher development in regulating career calling and job burnout.Therefore,on the one hand,we think that if managers want to reduce teachers’job burnout,they need to pay more attention to teachers’career adaptability and work engagement,rather than relying solely on teachers’career calling.On the other hand,it is to remind teachers not to rely on their adjustment to adapt to the work,but also to need outside help as much as possible.展开更多
The acetylpolyamine oxidase(APAO),spermine oxidase(SMO),and spermidine/spermine N1-acetyltransferase(SSAT)are pivotal enzymes in polyamine metabolism,exerting direct influence on polyamine homeostasis regulation.Dysfu...The acetylpolyamine oxidase(APAO),spermine oxidase(SMO),and spermidine/spermine N1-acetyltransferase(SSAT)are pivotal enzymes in polyamine metabolism,exerting direct influence on polyamine homeostasis regulation.Dysfunctions in these enzymes are intricately linked to inflammatory diseases and cancers.Establishing their three-dimensional structures is essential for exploring enzymatic catalytic mechanisms and designing inhibitors at the atomic level.This article primarily assesses the precision of AlphaFold2 and molecular dynamics simulations in determining the three-dimensional structures of these enzymes,utilizing protein conformation rationality assessment,residue correlation matrix,and other techniques.This provides robust models for subsequent polyamine catabolic metabolism calculations and offers valuable insights for modeling proteins that have yet to acquire crystal structures.展开更多
Porosity is an important attribute for evaluating the petrophysical properties of reservoirs, and has guiding significance for the exploration and development of oil and gas. The seismic inversion is a key method for ...Porosity is an important attribute for evaluating the petrophysical properties of reservoirs, and has guiding significance for the exploration and development of oil and gas. The seismic inversion is a key method for comprehensively obtaining the porosity. Deep learning methods provide an intelligent approach to suppress the ambiguity of the conventional inversion method. However, under the trace-bytrace inversion strategy, there is a lack of constraints from geological structural information, resulting in poor lateral continuity of prediction results. In addition, the heterogeneity and the sedimentary variability of subsurface media also lead to uncertainty in intelligent prediction. To achieve fine prediction of porosity, we consider the lateral continuity and variability and propose an improved structural modeling deep learning porosity prediction method. First, we combine well data, waveform attributes, and structural information as constraints to model geophysical parameters, constructing a high-quality training dataset with sedimentary facies-controlled significance. Subsequently, we introduce a gated axial attention mechanism to enhance the features of dataset and design a bidirectional closed-loop network system constrained by inversion and forward processes. The constraint coefficient is adaptively adjusted by the petrophysical information contained between the porosity and impedance in the study area. We demonstrate the effectiveness of the adaptive coefficient through numerical experiments.Finally, we compare the performance differences between the proposed method and conventional deep learning methods using data from two study areas. The proposed method achieves better consistency with the logging porosity, demonstrating the superiority of the proposed method.展开更多
Controversy is ongoing regarding the relationship between ore formation and the structural evolution of the Hadamengou gold deposit.To address this issue,we conducted a comprehensive investigation of mineralization-re...Controversy is ongoing regarding the relationship between ore formation and the structural evolution of the Hadamengou gold deposit.To address this issue,we conducted a comprehensive investigation of mineralization-related structures,geochronology and Fe isotopes.From the perspective of spatial evolution,hydrothermal fluids originating from the Shadegai and Xishadegai plutons have extracted accumulated ore-forming elements from the Wulashan Group(Ar2WL)and then evolved,initiating at Exploration Line 11 and migrating eastwards and westwards along the EW-trending thrust fault system to form orebodies.From the temporal evolution standpoint,the Wulashan Group(Ar_(2)WL)experienced diagenesis(2591.00 Ma to 2204.00 Ma)and metamorphism(2074.00 Ma to 1625.00 Ma)from late Neoarchean to early Paleoproterozoic,when ore-forming materials were initially accumulated;in the early Paleozoic(440.71 Ma to 425.00 Ma),the collision led to the formation of early-stage EW-trending imbricated thrust faults,which established a fundamental structural framework for the orefield and further accumulated ore-forming materials;from the late Paleozoic to the Mesozoic,multiple subsequent episodes of regional tectonic-magmatic-hydrothermal events have superimposed,modified and reactivated the thrust fault system.Notably,the Triassic period,particularly between 245.00 Ma and 217.90 Ma,is considered to be a primary ore-forming stage.In summary,the intricate relationship between ore-formation and structural evolution has been fundamentally elucidated.展开更多
Background:Resilience is crucial for medical college students to thrive in the highly stressful environment of medical education.However,the prevalence of problematic internet use(PIU)in this population may negatively...Background:Resilience is crucial for medical college students to thrive in the highly stressful environment of medical education.However,the prevalence of problematic internet use(PIU)in this population may negatively impact their resilience.This study investigated the influence of problematic online gaming(PG)and problematic social media use(PSMU)on the resilience of medical college students in China.Methods:A sample of 5075 first-year medical college students from four Chinese universities was studied.PG served as the independent variable,resilience as the dependent variable,fatigue as the mediator,and PSMU as the moderator.Structural equation modeling was conducted using LISREL 8.80.Additionally,a moderated mediation model was evaluated using the jAMM module in jamovi 2.6.13.Results:The study’s findings revealed significant negative correlations between resilience and the variables of PG,PSMU,and fatigue.Fatigue mediated the relationship between PG and resilience(B=−0.04,95%CI=[−0.05,−0.03]).PSMU moderated the direct relationship between PG and resilience with the interaction term PG×PSMU significant(B=−0.004,t=−6.501,p<0.001)and the first stage(PG→fatigue)of the mediation with PG×PSMU significant(B=0.055,t=8.351,p<0.001).The detrimental effects of PG on resilience were more pronounced among individuals with lower levels of PSMU.Conclusion:This study concluded that addressing PIU,particularly PG,is essential for fostering resilience in medical college students.While PSMU itself is maladaptive,the underlying social media engagement may serve a protective role through social support in mitigating the adverse effects of PG on resilience.展开更多
Dentistry is a profession with a high prevalence of work-related musculoskeletal disorders(WMSDs),with symptoms often appearing very early in one’s career[1].WMSDs are conditions affecting the muscles,bones,and nervo...Dentistry is a profession with a high prevalence of work-related musculoskeletal disorders(WMSDs),with symptoms often appearing very early in one’s career[1].WMSDs are conditions affecting the muscles,bones,and nervous system due to occupational factors.In 2002,the International Labor Organization included musculoskeletal diseases in the International List of Occupational Diseases.China’s recently updated Classification and Catalog of Occupational Diseases has introduced two new categories of occupational illnesses,including occupational musculoskeletal disorders.WMSDs significantly impact the health and work of dentists,reducing their quality of life and causing economic losses.These disorders are multifactorial in nature,influenced by personal,psychosocial,biomechanical,and environmental factors.Dentists frequently maintain static or awkward postures during procedures,which leads to musculoskeletal strain and discomfort;additionally,long working hours contribute to psychological stress,further increasing the risk of WMSDs[2].展开更多
Objective image quality assessment(IQA)plays an important role in various visual communication systems,which can automatically and efficiently predict the perceived quality of images.The human eye is the ultimate eval...Objective image quality assessment(IQA)plays an important role in various visual communication systems,which can automatically and efficiently predict the perceived quality of images.The human eye is the ultimate evaluator for visual experience,thus the modeling of human visual system(HVS)is a core issue for objective IQA and visual experience optimization.The traditional model based on black box fitting has low interpretability and it is difficult to guide the experience optimization effectively,while the model based on physiological simulation is hard to integrate into practical visual communication services due to its high computational complexity.For bridging the gap between signal distortion and visual experience,in this paper,we propose a novel perceptual no-reference(NR)IQA algorithm based on structural computational modeling of HVS.According to the mechanism of the human brain,we divide the visual signal processing into a low-level visual layer,a middle-level visual layer and a high-level visual layer,which conduct pixel information processing,primitive information processing and global image information processing,respectively.The natural scene statistics(NSS)based features,deep features and free-energy based features are extracted from these three layers.The support vector regression(SVR)is employed to aggregate features to the final quality prediction.Extensive experimental comparisons on three widely used benchmark IQA databases(LIVE,CSIQ and TID2013)demonstrate that our proposed metric is highly competitive with or outperforms the state-of-the-art NR IQA measures.展开更多
This paper presents a method for structured scene modeling using micro stereo vision system with large field of view. The proposed algorithm includes edge detection with Canny detector, line fitting with principle axi...This paper presents a method for structured scene modeling using micro stereo vision system with large field of view. The proposed algorithm includes edge detection with Canny detector, line fitting with principle axis based approach, finding corresponding lines using feature based matching method, and 3D line depth computation.展开更多
Enhancement of productivity optimization is steadily gaining the priority in mining companies especially in the underground coal mining industry which faces a daunting task to balance marginal profit generation with a...Enhancement of productivity optimization is steadily gaining the priority in mining companies especially in the underground coal mining industry which faces a daunting task to balance marginal profit generation with a comparatively high cost of production, volatile market price and rapid grade variation. This paper is aimed to analyze some of the causal factors both technical and site specific which are directly or indirectly impacting the productivity of the longwall coal mining system such as downtime of equipment system in longwall panel, overloading of conveyors and bin, preventive maintenance, gas management practices and injury severity rate. Structured Equation Modelling (SEM) was used to study the causal relationships between the above-mentioned factors and mine productivity. The equipment considered for analysis included shearer, armored face conveyor, crusher, bridge stage loader, chock supports, main gate drive, gate conveyor, hydraulic pumps and crusher. SEM was applied to relate the correlations existing among these causal variables in order to assess their direct or indirect impact on mining productivity. Based on the data extracted over a period of 10 months which included the extraction of 2 longwall panels, the study revealed a significant negative causal relationship between injury severity rate (p < 0.01) and equipment downtime (p = 0.001), with mine productivity. However, preventive maintenance delay time, gas management delay time and conveyor overloading delay time were found to have an insignificant direct influence on mine productivity but indirectly modify it through a significant mediator relationship with equipment downtime. This information would assist mine management to take proper preventive measures.展开更多
Aerogel nanoporous materials possess high porosity, high specific surface area, and extremely low density due to their unique nanoscale network structure. Moreover, their effective thermal conductivity is very low, ma...Aerogel nanoporous materials possess high porosity, high specific surface area, and extremely low density due to their unique nanoscale network structure. Moreover, their effective thermal conductivity is very low, making them a new type of lightweight and highly efficient nanoscale super-insulating material. However, prediction of their effective thermal conductivity is challenging due to their uneven pore size distribution. To investigate the internal heat transfer mechanism of aerogel nanoporous materials, this study constructed a cross-aligned and cubic pore model(CACPM) based on the actual pore arrangement of SiO_(2) aerogel. Based on the established CACPM, the effective thermal conductivity expression for the aerogel was derived by simultaneously considering gas-phase heat conduction, solid-phase heat conduction, and radiative heat transfer. The derived expression was then compared with available experimental data and the Wei structure model. The results indicate that, according to the model established in this study for the derived thermal conductivity formula of silica aerogel, for powdery silica aerogel under the conditions of T = 298 K, a_(2)= 0.85, D_(1)= 90 μm, ρ = 128 kg/m^(3), within the pressure range of 0–10^(5)Pa, the average deviation between the calculated values and experimental values is 10.51%. In the pressure range of 10^(3)–10^(4)Pa, the deviation between calculated values and experimental values is within 4%. Under these conditions, the model has certain reference value in engineering verification. This study also makes a certain contribution to the research of aerogel thermal conductivity heat transfer models and calculation formulae.展开更多
With drilling and seismic data of Transtensional(strike-slip)Fault System in the Ziyang area of the central Sichuan Basin,SW China plane-section integrated structural interpretation,3-D fault framework model building,...With drilling and seismic data of Transtensional(strike-slip)Fault System in the Ziyang area of the central Sichuan Basin,SW China plane-section integrated structural interpretation,3-D fault framework model building,fault throw analyzing,and balanced profile restoration,it is pointed out that the transtensional fault system in the Ziyang 3-D seismic survey consists of the northeast-trending F_(I)19 and F_(I)20 fault zones dominated by extensional deformation,as well as 3 sets of northwest-trending en echelon normal faults experienced dextral shear deformation.Among them,the F_(I)19 and F_(I)20 fault zones cut through the Neoproterozoic to Lower Triassic Jialingjiang Formation,presenting a 3-D structure of an“S”-shaped ribbon.And before Permian and during the Early Triassic,the F_(I)19 and F_(I)20 fault zones underwent at least two periods of structural superimposition.Besides,the 3 sets of northwest-trending en echelon normal faults are composed of small normal faults arranged in pairs,with opposite dip directions and partially left-stepped arrangement.And before Permian,they had formed almost,restricting the eastward growth and propagation of the F_(I)19 fault zone.The F_(I)19 and F_(I)20 fault zones communicate multiple sets of source rocks and reservoirs from deep to shallow,and the timing of fault activity matches well with oil and gas generation peaks.If there were favorable Cambrian-Triassic sedimentary facies and reservoirs developing on the local anticlinal belts of both sides of the F_(I)19 and F_(I)20 fault zones,the major reservoirs in this area are expected to achieve breakthroughs in oil and gas exploration.展开更多
The structural modeling of open-high-low-close(OHLC)data contained within the candlestick chart is crucial to financial practice.However,the inherent constraints in OHLC data pose immense challenges to its structural ...The structural modeling of open-high-low-close(OHLC)data contained within the candlestick chart is crucial to financial practice.However,the inherent constraints in OHLC data pose immense challenges to its structural modeling.Models that fail to process these constraints may yield results deviating from those of the original OHLC data structure.To address this issue,a novel unconstrained transformation method,along with its explicit inverse transformation,is proposed to properly handle the inherent constraints of OHLC data.A flexible and effective framework for structurally modeling OHLC data is designed,and the detailed procedure for modeling OHLC data through the vector autoregression and vector error correction model are provided as an example of multivariate time-series analysis.Extensive simulations and three authentic financial datasets from the Kweichow Moutai,CSI 100 index,and 50 ETF of the Chinese stock market demonstrate the effectiveness and stability of the proposed modeling approach.The modeling results of support vector regression provide further evidence that the proposed unconstrained transformation not only ensures structural forecasting of OHLC data but also is an effective feature-extraction method that can effectively improve the forecasting accuracy of machine-learning models for close prices.展开更多
Background:Meta-analysis is a quantitative approach that systematically integrates results from previous research to draw conclusions.Structural equation modelling is a statistical method that integrates factor analys...Background:Meta-analysis is a quantitative approach that systematically integrates results from previous research to draw conclusions.Structural equation modelling is a statistical method that integrates factor analysis and path analysis.Meta-analytic structural equation modeling(MASEM)combines meta-analysis and structural equation modeling.It allows researchers to explain relationships among a group of variables across multiple studies.Methods:We used a simulated dataset to conduct a univariate MASEM analysis,using Comprehensive Meta Analysis 3.3,Analysis of Moment Structures 24.0 software.Results:Despite the lack of concise literature on the methodology,our study provided a practical step-by-step guide on univariate MASEM.Conclusion:Researchers can employ MASEM analysis in applicable fields based on the description,principles,and practices expressed in this study and our previous publications mentioned in this study.展开更多
Ceramic relief mural is a contemporary landscape art that is carefully designed based on human nature,culture,and architectural wall space,combined with social customs,visual sensibility,and art.It may also become the...Ceramic relief mural is a contemporary landscape art that is carefully designed based on human nature,culture,and architectural wall space,combined with social customs,visual sensibility,and art.It may also become the main axis of ceramic art in the future.Taiwan public ceramic relief murals(PCRM)are most distinctive with the PCRM pioneered by Pan-Hsiung Chu of Meinong Kiln in 1987.In addition to breaking through the limitations of traditional public ceramic murals,Chu leveraged local culture and sensibility.The theme of art gives PCRM its unique style and innovative value throughout the Taiwan region.This study mainly analyzes and understands the design image of public ceramic murals,taking Taiwan PCRM’s design and creation as the scope,and applies STEEP analysis,that is,the social,technological,economic,ecological,and political-legal environments are analyzed as core factors;eight main important factors in the artistic design image of ceramic murals are evaluated.Then,interpretive structural modeling(ISM)is used to establish five levels,analyze the four main problems in the main core factor area and the four main target results in the affected factor area;and analyze the problem points and target points as well as their causal relationships.It is expected to sort out the relationship between these factors,obtain the hierarchical relationship of each factor,and provide a reference basis and research methods.展开更多
The Bayesian structural equation model integrates the principles of Bayesian statistics, providing a more flexible and comprehensive modeling framework. In exploring complex relationships between variables, handling u...The Bayesian structural equation model integrates the principles of Bayesian statistics, providing a more flexible and comprehensive modeling framework. In exploring complex relationships between variables, handling uncertainty, and dealing with missing data, the Bayesian structural equation model demonstrates unique advantages. Therefore, Bayesian methods are used in this paper to establish a structural equation model of innovative talent cognition, with the measurement of college students’ cognition of innovative talent being studied. An in-depth analysis is conducted on the effects of innovative self-efficacy, social resources, innovative personality traits, and school education, aiming to explore the factors influencing college students’ innovative talent. The results indicate that innovative self-efficacy plays a key role in perception, social resources are significantly positively correlated with the perception of innovative talents, innovative personality tendencies and school education are positively correlated with the perception of innovative talents, but the impact is not significant.展开更多
Translation project outcomes are affected by many factors.Hence,this study explored the impact of risk management ability of translators on translation project outcomes in China.In the study,we took risk management ab...Translation project outcomes are affected by many factors.Hence,this study explored the impact of risk management ability of translators on translation project outcomes in China.In the study,we took risk management ability of translators in translation projects as the research objective and collected research data through an online questionnaire to establish a structural equation model.Based on these data in the model,we analyzed impacts of translators’risk management ability on translation project outcomes.Evidently,risks in project planning during translation as well as proofreading and typesetting after translation affect the delivery and remuneration of translation.The study can help translators correctly recognize and manage the risks in translation practices,increase the success rate of translation projects and further promote the sound development of language services.展开更多
With the continuous advancement of education informatization,Technological Pedagogical Content Knowledge(TPACK),as a new theoretical framework,provides a novel method for measuring teachers’informatization teaching a...With the continuous advancement of education informatization,Technological Pedagogical Content Knowledge(TPACK),as a new theoretical framework,provides a novel method for measuring teachers’informatization teaching ability.This study takes normal students of English majors from three ethnic universities as the research object,collects relevant data through questionnaires,and uses structural equation modeling to conduct data analysis and empirical research to investigate the differences in the TPACK levels of these students at different grades and the structural relationships among the elements in the TPACK structure.The technological pedagogical knowledge element of the TPACK structure was not obtained by exploratory factors analysis but through path analysis and structural equation modeling,the results show that the one-dimensional core knowledge of technological knowledge(TK),content knowledge(CK),and pedagogical knowledge(PK)have a positive effect on the two-dimensional interaction knowledge of technological content knowledge(TCK)and pedagogical content knowledge(PCK);furthermore,TCK and PCK have a positive effect on TPACK;and TK,CK,and PK indirectly affect TPACK through TCK and PCK.On this basis,suggestions are provided to ethnic colleges and universities to develop the TPACK knowledge competence of normal students of English majors.展开更多
Tuojiang River Basin is a first-class tributary of the upper reaches of the Yangtze River—which is the longest river in China.As phytoplankton are sensitive indicators of trophic changes inwater bodies,characterizing...Tuojiang River Basin is a first-class tributary of the upper reaches of the Yangtze River—which is the longest river in China.As phytoplankton are sensitive indicators of trophic changes inwater bodies,characterizing phytoplankton communities and their growth influencing factors in polluted urban rivers can provide new ideas for pollution control.Here,we used direct microscopic count and environmental DNA(eDNA)metabarcoding methods to investigate phytoplankton community structure in Tuojiang River Basin(Chengdu,Sichuan Province,China).The association between phytoplankton community structure and water environmental factors was evaluated by Mantel analysis.Additional environmental monitoring data were used to pinpoint major factors that influenced phytoplankton growth based on structural equation modeling.At the phylum level,the dominant phytoplankton taxa identified by the conventional microscopic method mainly belonged to Bacillariophyta,Chlorophyta,and Cyanophyta,in contrast with Chlorophyta,Dinophyceae,and Bacillariophyta identified by eDNA metabarcoding.Inα-diversity analysis,eDNA metabarcoding detected greater species diversity and achieved higher precision than the microscopic method.Phytoplankton growth was largely limited by phosphorus based on the nitrogen-to-phosphorus ratios>16:1 in all water samples.Redundancy analysis and structural equation modeling also confirmed that the nitrogen-to-phosphorus ratio was the principal factor influencing phytoplankton growth.The results could be useful for implementing comprehensive management of the river basin environment.It is recommended to control the discharge of point-and surface-source pollutants and the concentration of dissolved oxygen in areas with excessive nutrients(e.g.,Jianyang-Ziyang).Algae monitoring techniques and removal strategies should be improved in 201 Hospital,Hongrihe Bridge and Colmar Town areas.展开更多
文摘A morphologically structured model is proposed to describe the batch fermentation of lovastatin according to the growth kinetics of filamentous microorganisms. Three kinds of hyphae are considered in the model: actively growing hyphae, non-growing hyphae and deactivated hyphae. Furthermore, actively growing hyphae consist of three morphological compartments: apical compartment which gives rise to hyphal tip extension; subapical compartment which is related to hyphal branching; and hyphal compartment which is only responsible for secondary metabolite formation. The kinetics of mycelial growth mechanism is summarized and applied in modeling lovastatin fermentation. A Michaelis-Menten kinetic model with substrate inhibition is proposed for product formation. As expected, the model simulations fit well with experimental data obtained either from a laboratory scale 10L fer-menter or from a pilot-plant scale fermenter.
文摘The growth of filamentous microorganism is contributed by tip extension and branching. The microscopic growth of filamentous microorganism means the growth process from one or a few spores. In order to describe the microscopic process, a population morphologically structured model is proposed, in which three morphological compartment and their interactions were considered, and the heterogeneity of hyphal growth was included. The model was applied to describe the microscopic growth of Streptomyces tendae and Geotrichum candidum with good agreement. From model prediction, it is concluded that if the number of hyphae is large enough (macroscopic growth), the specific growth rate of filamentous microorganism and the ratio of morphological forms in hyphae will become constant.
基金funded by Humanities and Social Sciences Foundation and Natural Science Foundation of Nanjing University of Posts and Telecommunications(NYY222055,NY224176)General Subject of Educational Science Planning in Jiangsu Province(C/2024/01/76)National Natural Science Foundation of China(62307025).
文摘Objectives:Teachers are facing unprecedented new challenges leading them to face an increasing number of tasks that are not part of their job,as well as having to cope with the additional skills acquisition that comes with non-traditional forms of teaching and learning,and increased work pressure leading to an increase in the rate of teachers leaving the profession.Therefore,this study aims to explore the mechanism of the career calling on job burnout through career adaptability and work engagement.Methods:This study conducted a cross-sectional survey of 465 primary and secondary school teachers(PSST)in China's Mainland from the perspective of work adjustment and used structural equation modeling(SEM)to examine the mediating roles of career adaptability and work engagement in the relationship between teachers’career calling and job burnout.Results:The results show that PSSTs are above average in career calling,career adaptability,and work engagement,while job burnout is below average.A significant positive or negative correlation exists between career calling,career adaptability,work engagement,and job burnout.The result of path analysis indicates that career adaptability and work engagement exert an indirect influence on the job burnout of PSST through three paths:namely,the independent intermediary role of career adaptability(EV=−0.144),the independent intermediary role of work engagement(EV=0.172)and the chain intermediary role of the two(EV=0.176).Conclusion:This study emphasizes the importance of career adaptability and work engagement in teacher development in regulating career calling and job burnout.Therefore,on the one hand,we think that if managers want to reduce teachers’job burnout,they need to pay more attention to teachers’career adaptability and work engagement,rather than relying solely on teachers’career calling.On the other hand,it is to remind teachers not to rely on their adjustment to adapt to the work,but also to need outside help as much as possible.
基金National Natural Science Foundation of China(22073023)Natural Science Foundation of Henan Province(242300421134)+1 种基金the Young Backbone Teacher in Colleges and Universities of Henan Province(2021GGJS020)Foundation of State Key Laboratory of Antiviral Drugs。
文摘The acetylpolyamine oxidase(APAO),spermine oxidase(SMO),and spermidine/spermine N1-acetyltransferase(SSAT)are pivotal enzymes in polyamine metabolism,exerting direct influence on polyamine homeostasis regulation.Dysfunctions in these enzymes are intricately linked to inflammatory diseases and cancers.Establishing their three-dimensional structures is essential for exploring enzymatic catalytic mechanisms and designing inhibitors at the atomic level.This article primarily assesses the precision of AlphaFold2 and molecular dynamics simulations in determining the three-dimensional structures of these enzymes,utilizing protein conformation rationality assessment,residue correlation matrix,and other techniques.This provides robust models for subsequent polyamine catabolic metabolism calculations and offers valuable insights for modeling proteins that have yet to acquire crystal structures.
基金the support of Research Program of Fine Exploration and Surrounding Rock Classification Technology for Deep Buried Long Tunnels Driven by Horizontal Directional Drilling and Magnetotelluric Methods Based on Deep Learning under Grant E202408010the Sichuan Science and Technology Program under Grant 2024NSFSC1984 and Grant 2024NSFSC1990。
文摘Porosity is an important attribute for evaluating the petrophysical properties of reservoirs, and has guiding significance for the exploration and development of oil and gas. The seismic inversion is a key method for comprehensively obtaining the porosity. Deep learning methods provide an intelligent approach to suppress the ambiguity of the conventional inversion method. However, under the trace-bytrace inversion strategy, there is a lack of constraints from geological structural information, resulting in poor lateral continuity of prediction results. In addition, the heterogeneity and the sedimentary variability of subsurface media also lead to uncertainty in intelligent prediction. To achieve fine prediction of porosity, we consider the lateral continuity and variability and propose an improved structural modeling deep learning porosity prediction method. First, we combine well data, waveform attributes, and structural information as constraints to model geophysical parameters, constructing a high-quality training dataset with sedimentary facies-controlled significance. Subsequently, we introduce a gated axial attention mechanism to enhance the features of dataset and design a bidirectional closed-loop network system constrained by inversion and forward processes. The constraint coefficient is adaptively adjusted by the petrophysical information contained between the porosity and impedance in the study area. We demonstrate the effectiveness of the adaptive coefficient through numerical experiments.Finally, we compare the performance differences between the proposed method and conventional deep learning methods using data from two study areas. The proposed method achieves better consistency with the logging porosity, demonstrating the superiority of the proposed method.
基金the financial support by the Major Research Plan of National Natural Science Foundation of China(92062219)the Young Elite Scientists Sponsorship Program by BAST(No.BYESS2023411)+2 种基金the Open Research Project from the State Key Laboratory of Geological Processes and Mineral Resources,China University of Geosciences(GPMR202407)the Geological Survey Project of the China Geological Survey„General survey of Hadamengou Rock Gold Deposit in Inner Mongolia'(DD20191017)the Geological Survey Project(H90063).
文摘Controversy is ongoing regarding the relationship between ore formation and the structural evolution of the Hadamengou gold deposit.To address this issue,we conducted a comprehensive investigation of mineralization-related structures,geochronology and Fe isotopes.From the perspective of spatial evolution,hydrothermal fluids originating from the Shadegai and Xishadegai plutons have extracted accumulated ore-forming elements from the Wulashan Group(Ar2WL)and then evolved,initiating at Exploration Line 11 and migrating eastwards and westwards along the EW-trending thrust fault system to form orebodies.From the temporal evolution standpoint,the Wulashan Group(Ar_(2)WL)experienced diagenesis(2591.00 Ma to 2204.00 Ma)and metamorphism(2074.00 Ma to 1625.00 Ma)from late Neoarchean to early Paleoproterozoic,when ore-forming materials were initially accumulated;in the early Paleozoic(440.71 Ma to 425.00 Ma),the collision led to the formation of early-stage EW-trending imbricated thrust faults,which established a fundamental structural framework for the orefield and further accumulated ore-forming materials;from the late Paleozoic to the Mesozoic,multiple subsequent episodes of regional tectonic-magmatic-hydrothermal events have superimposed,modified and reactivated the thrust fault system.Notably,the Triassic period,particularly between 245.00 Ma and 217.90 Ma,is considered to be a primary ore-forming stage.In summary,the intricate relationship between ore-formation and structural evolution has been fundamentally elucidated.
基金supported by General Education Project of the National Social Science Foundation in 2020:“Multi-Dimensional Reconstruction of Peer Review Mechanisms in the Evaluation of Scientific and Technological Talents in Universities(BIA200167).”。
文摘Background:Resilience is crucial for medical college students to thrive in the highly stressful environment of medical education.However,the prevalence of problematic internet use(PIU)in this population may negatively impact their resilience.This study investigated the influence of problematic online gaming(PG)and problematic social media use(PSMU)on the resilience of medical college students in China.Methods:A sample of 5075 first-year medical college students from four Chinese universities was studied.PG served as the independent variable,resilience as the dependent variable,fatigue as the mediator,and PSMU as the moderator.Structural equation modeling was conducted using LISREL 8.80.Additionally,a moderated mediation model was evaluated using the jAMM module in jamovi 2.6.13.Results:The study’s findings revealed significant negative correlations between resilience and the variables of PG,PSMU,and fatigue.Fatigue mediated the relationship between PG and resilience(B=−0.04,95%CI=[−0.05,−0.03]).PSMU moderated the direct relationship between PG and resilience with the interaction term PG×PSMU significant(B=−0.004,t=−6.501,p<0.001)and the first stage(PG→fatigue)of the mediation with PG×PSMU significant(B=0.055,t=8.351,p<0.001).The detrimental effects of PG on resilience were more pronounced among individuals with lower levels of PSMU.Conclusion:This study concluded that addressing PIU,particularly PG,is essential for fostering resilience in medical college students.While PSMU itself is maladaptive,the underlying social media engagement may serve a protective role through social support in mitigating the adverse effects of PG on resilience.
基金supported by the 2021 Shandong Province Higher Education Institutions“Youth Innovation Talent Introduction and Cultivation Plan”(Public Health Safety Risk Assessment and Response Innovation Team)National Traditional Chinese Medicine Comprehensive Reform Demonstration Zone Science and Technology Co construction Project(No.GZYKJSSD-2024-106)Research Project of Shandong Educational Supervision Society(No.SDJYDDXH2023-2159).
文摘Dentistry is a profession with a high prevalence of work-related musculoskeletal disorders(WMSDs),with symptoms often appearing very early in one’s career[1].WMSDs are conditions affecting the muscles,bones,and nervous system due to occupational factors.In 2002,the International Labor Organization included musculoskeletal diseases in the International List of Occupational Diseases.China’s recently updated Classification and Catalog of Occupational Diseases has introduced two new categories of occupational illnesses,including occupational musculoskeletal disorders.WMSDs significantly impact the health and work of dentists,reducing their quality of life and causing economic losses.These disorders are multifactorial in nature,influenced by personal,psychosocial,biomechanical,and environmental factors.Dentists frequently maintain static or awkward postures during procedures,which leads to musculoskeletal strain and discomfort;additionally,long working hours contribute to psychological stress,further increasing the risk of WMSDs[2].
基金This work was supported by National Natural Science Foundation of China(Nos.61831015 and 61901260)Key Research and Development Program of China(No.2019YFB1405902).
文摘Objective image quality assessment(IQA)plays an important role in various visual communication systems,which can automatically and efficiently predict the perceived quality of images.The human eye is the ultimate evaluator for visual experience,thus the modeling of human visual system(HVS)is a core issue for objective IQA and visual experience optimization.The traditional model based on black box fitting has low interpretability and it is difficult to guide the experience optimization effectively,while the model based on physiological simulation is hard to integrate into practical visual communication services due to its high computational complexity.For bridging the gap between signal distortion and visual experience,in this paper,we propose a novel perceptual no-reference(NR)IQA algorithm based on structural computational modeling of HVS.According to the mechanism of the human brain,we divide the visual signal processing into a low-level visual layer,a middle-level visual layer and a high-level visual layer,which conduct pixel information processing,primitive information processing and global image information processing,respectively.The natural scene statistics(NSS)based features,deep features and free-energy based features are extracted from these three layers.The support vector regression(SVR)is employed to aggregate features to the final quality prediction.Extensive experimental comparisons on three widely used benchmark IQA databases(LIVE,CSIQ and TID2013)demonstrate that our proposed metric is highly competitive with or outperforms the state-of-the-art NR IQA measures.
文摘This paper presents a method for structured scene modeling using micro stereo vision system with large field of view. The proposed algorithm includes edge detection with Canny detector, line fitting with principle axis based approach, finding corresponding lines using feature based matching method, and 3D line depth computation.
文摘Enhancement of productivity optimization is steadily gaining the priority in mining companies especially in the underground coal mining industry which faces a daunting task to balance marginal profit generation with a comparatively high cost of production, volatile market price and rapid grade variation. This paper is aimed to analyze some of the causal factors both technical and site specific which are directly or indirectly impacting the productivity of the longwall coal mining system such as downtime of equipment system in longwall panel, overloading of conveyors and bin, preventive maintenance, gas management practices and injury severity rate. Structured Equation Modelling (SEM) was used to study the causal relationships between the above-mentioned factors and mine productivity. The equipment considered for analysis included shearer, armored face conveyor, crusher, bridge stage loader, chock supports, main gate drive, gate conveyor, hydraulic pumps and crusher. SEM was applied to relate the correlations existing among these causal variables in order to assess their direct or indirect impact on mining productivity. Based on the data extracted over a period of 10 months which included the extraction of 2 longwall panels, the study revealed a significant negative causal relationship between injury severity rate (p < 0.01) and equipment downtime (p = 0.001), with mine productivity. However, preventive maintenance delay time, gas management delay time and conveyor overloading delay time were found to have an insignificant direct influence on mine productivity but indirectly modify it through a significant mediator relationship with equipment downtime. This information would assist mine management to take proper preventive measures.
基金supported by the National Natural Science Foundation of China (Grant Nos. 51764046 and 52160013)the Inner Mongolia Autonomous Region Postgraduate Research Innovation Project of China (Grant No. S20231165Z)the Research Program of Science and Technology at Universities of Inner Mongolia Autonomous Region of China (Grant Nos. 2023RCTD016 and 2024RCTD008)。
文摘Aerogel nanoporous materials possess high porosity, high specific surface area, and extremely low density due to their unique nanoscale network structure. Moreover, their effective thermal conductivity is very low, making them a new type of lightweight and highly efficient nanoscale super-insulating material. However, prediction of their effective thermal conductivity is challenging due to their uneven pore size distribution. To investigate the internal heat transfer mechanism of aerogel nanoporous materials, this study constructed a cross-aligned and cubic pore model(CACPM) based on the actual pore arrangement of SiO_(2) aerogel. Based on the established CACPM, the effective thermal conductivity expression for the aerogel was derived by simultaneously considering gas-phase heat conduction, solid-phase heat conduction, and radiative heat transfer. The derived expression was then compared with available experimental data and the Wei structure model. The results indicate that, according to the model established in this study for the derived thermal conductivity formula of silica aerogel, for powdery silica aerogel under the conditions of T = 298 K, a_(2)= 0.85, D_(1)= 90 μm, ρ = 128 kg/m^(3), within the pressure range of 0–10^(5)Pa, the average deviation between the calculated values and experimental values is 10.51%. In the pressure range of 10^(3)–10^(4)Pa, the deviation between calculated values and experimental values is within 4%. Under these conditions, the model has certain reference value in engineering verification. This study also makes a certain contribution to the research of aerogel thermal conductivity heat transfer models and calculation formulae.
基金Supported by the Key Project of National Natural Science Foundation of China(42330810).
文摘With drilling and seismic data of Transtensional(strike-slip)Fault System in the Ziyang area of the central Sichuan Basin,SW China plane-section integrated structural interpretation,3-D fault framework model building,fault throw analyzing,and balanced profile restoration,it is pointed out that the transtensional fault system in the Ziyang 3-D seismic survey consists of the northeast-trending F_(I)19 and F_(I)20 fault zones dominated by extensional deformation,as well as 3 sets of northwest-trending en echelon normal faults experienced dextral shear deformation.Among them,the F_(I)19 and F_(I)20 fault zones cut through the Neoproterozoic to Lower Triassic Jialingjiang Formation,presenting a 3-D structure of an“S”-shaped ribbon.And before Permian and during the Early Triassic,the F_(I)19 and F_(I)20 fault zones underwent at least two periods of structural superimposition.Besides,the 3 sets of northwest-trending en echelon normal faults are composed of small normal faults arranged in pairs,with opposite dip directions and partially left-stepped arrangement.And before Permian,they had formed almost,restricting the eastward growth and propagation of the F_(I)19 fault zone.The F_(I)19 and F_(I)20 fault zones communicate multiple sets of source rocks and reservoirs from deep to shallow,and the timing of fault activity matches well with oil and gas generation peaks.If there were favorable Cambrian-Triassic sedimentary facies and reservoirs developing on the local anticlinal belts of both sides of the F_(I)19 and F_(I)20 fault zones,the major reservoirs in this area are expected to achieve breakthroughs in oil and gas exploration.
基金the financial support from the Beijing Natural Science Foundation(Grant No.9244030)the National Natural Science Foundation of China(Grant Nos.72021001,11701023).
文摘The structural modeling of open-high-low-close(OHLC)data contained within the candlestick chart is crucial to financial practice.However,the inherent constraints in OHLC data pose immense challenges to its structural modeling.Models that fail to process these constraints may yield results deviating from those of the original OHLC data structure.To address this issue,a novel unconstrained transformation method,along with its explicit inverse transformation,is proposed to properly handle the inherent constraints of OHLC data.A flexible and effective framework for structurally modeling OHLC data is designed,and the detailed procedure for modeling OHLC data through the vector autoregression and vector error correction model are provided as an example of multivariate time-series analysis.Extensive simulations and three authentic financial datasets from the Kweichow Moutai,CSI 100 index,and 50 ETF of the Chinese stock market demonstrate the effectiveness and stability of the proposed modeling approach.The modeling results of support vector regression provide further evidence that the proposed unconstrained transformation not only ensures structural forecasting of OHLC data but also is an effective feature-extraction method that can effectively improve the forecasting accuracy of machine-learning models for close prices.
文摘Background:Meta-analysis is a quantitative approach that systematically integrates results from previous research to draw conclusions.Structural equation modelling is a statistical method that integrates factor analysis and path analysis.Meta-analytic structural equation modeling(MASEM)combines meta-analysis and structural equation modeling.It allows researchers to explain relationships among a group of variables across multiple studies.Methods:We used a simulated dataset to conduct a univariate MASEM analysis,using Comprehensive Meta Analysis 3.3,Analysis of Moment Structures 24.0 software.Results:Despite the lack of concise literature on the methodology,our study provided a practical step-by-step guide on univariate MASEM.Conclusion:Researchers can employ MASEM analysis in applicable fields based on the description,principles,and practices expressed in this study and our previous publications mentioned in this study.
文摘Ceramic relief mural is a contemporary landscape art that is carefully designed based on human nature,culture,and architectural wall space,combined with social customs,visual sensibility,and art.It may also become the main axis of ceramic art in the future.Taiwan public ceramic relief murals(PCRM)are most distinctive with the PCRM pioneered by Pan-Hsiung Chu of Meinong Kiln in 1987.In addition to breaking through the limitations of traditional public ceramic murals,Chu leveraged local culture and sensibility.The theme of art gives PCRM its unique style and innovative value throughout the Taiwan region.This study mainly analyzes and understands the design image of public ceramic murals,taking Taiwan PCRM’s design and creation as the scope,and applies STEEP analysis,that is,the social,technological,economic,ecological,and political-legal environments are analyzed as core factors;eight main important factors in the artistic design image of ceramic murals are evaluated.Then,interpretive structural modeling(ISM)is used to establish five levels,analyze the four main problems in the main core factor area and the four main target results in the affected factor area;and analyze the problem points and target points as well as their causal relationships.It is expected to sort out the relationship between these factors,obtain the hierarchical relationship of each factor,and provide a reference basis and research methods.
文摘The Bayesian structural equation model integrates the principles of Bayesian statistics, providing a more flexible and comprehensive modeling framework. In exploring complex relationships between variables, handling uncertainty, and dealing with missing data, the Bayesian structural equation model demonstrates unique advantages. Therefore, Bayesian methods are used in this paper to establish a structural equation model of innovative talent cognition, with the measurement of college students’ cognition of innovative talent being studied. An in-depth analysis is conducted on the effects of innovative self-efficacy, social resources, innovative personality traits, and school education, aiming to explore the factors influencing college students’ innovative talent. The results indicate that innovative self-efficacy plays a key role in perception, social resources are significantly positively correlated with the perception of innovative talents, innovative personality tendencies and school education are positively correlated with the perception of innovative talents, but the impact is not significant.
文摘Translation project outcomes are affected by many factors.Hence,this study explored the impact of risk management ability of translators on translation project outcomes in China.In the study,we took risk management ability of translators in translation projects as the research objective and collected research data through an online questionnaire to establish a structural equation model.Based on these data in the model,we analyzed impacts of translators’risk management ability on translation project outcomes.Evidently,risks in project planning during translation as well as proofreading and typesetting after translation affect the delivery and remuneration of translation.The study can help translators correctly recognize and manage the risks in translation practices,increase the success rate of translation projects and further promote the sound development of language services.
文摘With the continuous advancement of education informatization,Technological Pedagogical Content Knowledge(TPACK),as a new theoretical framework,provides a novel method for measuring teachers’informatization teaching ability.This study takes normal students of English majors from three ethnic universities as the research object,collects relevant data through questionnaires,and uses structural equation modeling to conduct data analysis and empirical research to investigate the differences in the TPACK levels of these students at different grades and the structural relationships among the elements in the TPACK structure.The technological pedagogical knowledge element of the TPACK structure was not obtained by exploratory factors analysis but through path analysis and structural equation modeling,the results show that the one-dimensional core knowledge of technological knowledge(TK),content knowledge(CK),and pedagogical knowledge(PK)have a positive effect on the two-dimensional interaction knowledge of technological content knowledge(TCK)and pedagogical content knowledge(PCK);furthermore,TCK and PCK have a positive effect on TPACK;and TK,CK,and PK indirectly affect TPACK through TCK and PCK.On this basis,suggestions are provided to ethnic colleges and universities to develop the TPACK knowledge competence of normal students of English majors.
基金supported by the National Natural Science Foundation of China (No.72091511)the Science Fund for Distinguished Young Scholars of Hebei Province (No.E2022402064).
文摘Tuojiang River Basin is a first-class tributary of the upper reaches of the Yangtze River—which is the longest river in China.As phytoplankton are sensitive indicators of trophic changes inwater bodies,characterizing phytoplankton communities and their growth influencing factors in polluted urban rivers can provide new ideas for pollution control.Here,we used direct microscopic count and environmental DNA(eDNA)metabarcoding methods to investigate phytoplankton community structure in Tuojiang River Basin(Chengdu,Sichuan Province,China).The association between phytoplankton community structure and water environmental factors was evaluated by Mantel analysis.Additional environmental monitoring data were used to pinpoint major factors that influenced phytoplankton growth based on structural equation modeling.At the phylum level,the dominant phytoplankton taxa identified by the conventional microscopic method mainly belonged to Bacillariophyta,Chlorophyta,and Cyanophyta,in contrast with Chlorophyta,Dinophyceae,and Bacillariophyta identified by eDNA metabarcoding.Inα-diversity analysis,eDNA metabarcoding detected greater species diversity and achieved higher precision than the microscopic method.Phytoplankton growth was largely limited by phosphorus based on the nitrogen-to-phosphorus ratios>16:1 in all water samples.Redundancy analysis and structural equation modeling also confirmed that the nitrogen-to-phosphorus ratio was the principal factor influencing phytoplankton growth.The results could be useful for implementing comprehensive management of the river basin environment.It is recommended to control the discharge of point-and surface-source pollutants and the concentration of dissolved oxygen in areas with excessive nutrients(e.g.,Jianyang-Ziyang).Algae monitoring techniques and removal strategies should be improved in 201 Hospital,Hongrihe Bridge and Colmar Town areas.
