A lot of norbornene derivatives and lactones are widely used as fragrant components in food or cosmetics. We expected that a series of new compounds with better odor character could be obtained when these two skeleton...A lot of norbornene derivatives and lactones are widely used as fragrant components in food or cosmetics. We expected that a series of new compounds with better odor character could be obtained when these two skeleton structures were combined. Thus, a series of endoand exo-5,5-disubstituted-3-oxo-4-oxatricyclo[5,2,1,0;]dec-8-enes（Ⅰ） were synthesized.展开更多
In order to investigate the structure-odor relationship of odoriferous compounds and search for new aroma chemicals, seven acetals of 4-trimethylsilyl-3-cyclohexenone and their carbon counterparts were synthesized by ...In order to investigate the structure-odor relationship of odoriferous compounds and search for new aroma chemicals, seven acetals of 4-trimethylsilyl-3-cyclohexenone and their carbon counterparts were synthesized by Birch reduction of 4-substituted anisoles and then acetalization. Seven acetals of 4-trimethylsilylcyclohexanone and their carbon counterparts were synthesized similarly. Structures of all new compounds were determined by MS, IR and ~1H NMR, and their characteristic odors were evaluated as well. The characteristic odors of the acetals formed by 4-substituted-3-cyclohexenone and 1, 2-diols are fruity and woody. The acetals formed from 1, 3-diols are woody, and formed with 1, 4-diols are very faint in odor. Odors of acetals of 4-substituted cyclohexanone are all very weak. As a whole, odors of organosilicon compounds are weaker, but somewhat more delicate than their carbon counter- parts.展开更多
文摘A lot of norbornene derivatives and lactones are widely used as fragrant components in food or cosmetics. We expected that a series of new compounds with better odor character could be obtained when these two skeleton structures were combined. Thus, a series of endoand exo-5,5-disubstituted-3-oxo-4-oxatricyclo[5,2,1,0;]dec-8-enes（Ⅰ） were synthesized.
基金Project supported by NSFCNational Laboratory of Elemento-Organic Chemistry.
文摘In order to investigate the structure-odor relationship of odoriferous compounds and search for new aroma chemicals, seven acetals of 4-trimethylsilyl-3-cyclohexenone and their carbon counterparts were synthesized by Birch reduction of 4-substituted anisoles and then acetalization. Seven acetals of 4-trimethylsilylcyclohexanone and their carbon counterparts were synthesized similarly. Structures of all new compounds were determined by MS, IR and ~1H NMR, and their characteristic odors were evaluated as well. The characteristic odors of the acetals formed by 4-substituted-3-cyclohexenone and 1, 2-diols are fruity and woody. The acetals formed from 1, 3-diols are woody, and formed with 1, 4-diols are very faint in odor. Odors of acetals of 4-substituted cyclohexanone are all very weak. As a whole, odors of organosilicon compounds are weaker, but somewhat more delicate than their carbon counter- parts.
