The acetylpolyamine oxidase(APAO),spermine oxidase(SMO),and spermidine/spermine N1-acetyltransferase(SSAT)are pivotal enzymes in polyamine metabolism,exerting direct influence on polyamine homeostasis regulation.Dysfu...The acetylpolyamine oxidase(APAO),spermine oxidase(SMO),and spermidine/spermine N1-acetyltransferase(SSAT)are pivotal enzymes in polyamine metabolism,exerting direct influence on polyamine homeostasis regulation.Dysfunctions in these enzymes are intricately linked to inflammatory diseases and cancers.Establishing their three-dimensional structures is essential for exploring enzymatic catalytic mechanisms and designing inhibitors at the atomic level.This article primarily assesses the precision of AlphaFold2 and molecular dynamics simulations in determining the three-dimensional structures of these enzymes,utilizing protein conformation rationality assessment,residue correlation matrix,and other techniques.This provides robust models for subsequent polyamine catabolic metabolism calculations and offers valuable insights for modeling proteins that have yet to acquire crystal structures.展开更多
As the core content of pragmatic translation teaching research,pragmatic translation skill is closely correlated with translation technique and operation field.Viewed from the current English teaching situation in col...As the core content of pragmatic translation teaching research,pragmatic translation skill is closely correlated with translation technique and operation field.Viewed from the current English teaching situation in colleges and universities,translation skill is not cultivated as an independent language competence.Moreover,its research is insufficient.On account of this,the author first gives an introduction to pragmatic translation skill and pragmatic translation skill structure model in this paper.On this basis,the author also analyzes the application of pragmatic translation skill structure model in translation teaching.展开更多
Although human beings have come to understand and utilize coal for a very long history, no theoretical breakthrough in the study of coal structure has been made, which still needs continuous efforts of coal chemical w...Although human beings have come to understand and utilize coal for a very long history, no theoretical breakthrough in the study of coal structure has been made, which still needs continuous efforts of coal chemical workers. Based on the viewpoint of ‘vague/clear', the species classification and accurate analysis on coal were conducted by using the natural clustering all-component separation method. A more systematic and detailed coal embedded structure model theory which is suitable for coal of all ranks was developed from the previous one and a more complete theoretical system about the component and structure of coal was constructed. The whole establishment process of the theory was summarized and some of the main support data and analysis test results, including TEM, AFM, FTIR, GC/MS, MALDI/TOF/MS, DART/MSD, fractal analysis and so on were provided. The coal embedded structure theory fully considers both the identity and the particularity of all-rank coal, reflects the coal component and structure in the full range of coal rank, solves the systematic cognitive problem of coal component and structure on macro and micro level, and provides a valuable and meaningful theoretical approach for the coal processing and conversion technology.展开更多
Uncertainty in 3D geological structure models has become a bottleneck that restricts the development and application of 3D geological modeling.In order to solve this problem during periods of accuracy assessment,error...Uncertainty in 3D geological structure models has become a bottleneck that restricts the development and application of 3D geological modeling.In order to solve this problem during periods of accuracy assessment,error detection and dynamic correction in 3D geological structure models,we have reviewed the current situation and development trends in 3D geological modeling.The main context of uncertainty in 3D geological structure models is discussed.Major research issues and a general framework system of uncertainty in 3D geological structure models are proposed.We have described in detail the integration of development practices of 3D geological modeling systems,as well as the implementation process for uncertainty evaluation in 3D geological structure models.This study has laid the basis to build theoretical and methodological systems for accuracy assessment and error correction in 3D geological models and can assist in improving 3D modeling techniques under complex geological conditions.展开更多
When Kalman filter is used in the estimation of Vasicek term structure of interest rates,it is usual to assume that the measurement noise is uncorrelated.Study results are more favorable to the assumption of correlate...When Kalman filter is used in the estimation of Vasicek term structure of interest rates,it is usual to assume that the measurement noise is uncorrelated.Study results are more favorable to the assumption of correlated measurement noise.An augmented state Kalman filter form for Vasicek model is proposed to optimally estimate the unobservable state variable with the assumption of correlated measurement noise.Empirical results indicate that the model with sequentially correlated measurement noise can more accurately describe the dynamics of the term structure of interest rates.展开更多
Structure model of granules, boundary value of nucleus and powder, and the relationship between granula- tion efficiency and boundary value were investigated. Granules of sintering mixtures are composed of adhesive po...Structure model of granules, boundary value of nucleus and powder, and the relationship between granula- tion efficiency and boundary value were investigated. Granules of sintering mixtures are composed of adhesive powder and nucleus. In the mixtures, particles larger than 1.00 mm act as nucleus and particles smaller than 0.25 mm act as adhesive powder. Particles with size between 0.25--1.00 mm can be adhesive powder as well as nucleus depending on the granulation conditions. When the boundary value is close to 0.25 mm, the granulation efficiency is lower than 50%. When the boundary value is close to 1.00 mm, the granulation efficiency is above 90%. The boundary value is influenced by the iron ore type, granulation moisture, fineness of raw materials and burnt-lime activity. Good adhe- sive capability, suitable moisture content, appropriate particle size distribution and high burnt-lime activity make the boundary value move towards 1.00 mm and improve the granulation efficiency.展开更多
Accurate identification of influential nodes facilitates the control of rumor propagation and interrupts the spread of computer viruses.Many classical approaches have been proposed by researchers regarding different a...Accurate identification of influential nodes facilitates the control of rumor propagation and interrupts the spread of computer viruses.Many classical approaches have been proposed by researchers regarding different aspects.To explore the impact of location information in depth,this paper proposes an improved global structure model to characterize the influence of nodes.The method considers both the node’s self-information and the role of the location information of neighboring nodes.First,degree centrality of each node is calculated,and then degree value of each node is used to represent self-influence,and degree values of the neighbor layer nodes are divided by the power of the path length,which is path attenuation used to represent global influence.Finally,an extended improved global structure model that considers the nearest neighbor information after combining self-influence and global influence is proposed to identify influential nodes.In this paper,the propagation process of a real network is obtained by simulation with the SIR model,and the effectiveness of the proposed method is verified from two aspects of discrimination and accuracy.The experimental results show that the proposed method is more accurate in identifying influential nodes than other comparative methods with multiple networks.展开更多
In order to solve the problem that the embedded software has the shortcoming of the platform dependence, this paper presents an embedded software analysis method based on the static structure model. Before control flo...In order to solve the problem that the embedded software has the shortcoming of the platform dependence, this paper presents an embedded software analysis method based on the static structure model. Before control flow and data flow analysis, a lexical analysis/syntax analysis method with simplified grammar and sentence depth is designed to analyze the embedded software. The experiments use the open source code of smart meters as a case, and the artificial faults as the test objects, repeating 30 times. Compared with the popular static analyzing tools PC-Lint and Splint, the method can accurately orient 91% faults, which is between PC-Lint＇s 95% and Splint＇s 85%. The result indicates that the correct rate of our method is acceptable. Meanwhile, by removing the platform-dependent operation with simplified syntax analysis, our method is independent of development environment. It also shows that the method is applicable to the compiled C（including embedded software） program.展开更多
. In this article, we describe the characteristics of large-scale modeling of the theme text of this site data and important progress in recent years. Topic modeling approach has attracted wide interest in the world, .... In this article, we describe the characteristics of large-scale modeling of the theme text of this site data and important progress in recent years. Topic modeling approach has attracted wide interest in the world, and promote a number of important data mining, development of computer vision and computational biology applications, including automatic text summaries, information retrieval, information recommendation, topic detection and tracking, natural scene understanding human action recognition and gene expression analysis. The main features of the model and the corresponding theme paper focuses on the text of this site data. Data with dynamic, high-end, multi-channel and distributed structure and the structure of the model is only part of the theme before modeling. The paper discussed in the framework of the unity of the three-dimensional Markov model of four structural features of the text of this site data modeling, and analysis of distributed computing and word combination of three-dimensional modeling topics Markov model and type fuzzy systems the possibility of applications. In addition to structural modeling for this site text data, also we discuss some of the three-dimensional Markov model energy minimization of machine learning algorithms.展开更多
A structure model of urban traffic system evolution is built based on the analysis of the factors influencing the system evolution and the hierarchy between the factors. Then the influencing degrees of the factors are...A structure model of urban traffic system evolution is built based on the analysis of the factors influencing the system evolution and the hierarchy between the factors. Then the influencing degrees of the factors are quantificationally analyzed by DEMATE （decision making trial and evaluation laboratory）. The analysis results indicate that the traffic mode structure which achieves the highest central degree is the dominant influencing factor of the urban traffic system evolution, and that economy development and the traffic policy are the second important factors that also affect the Waffle mode structures. Furthermore, physical geography is a basic restriction to the urban traffic system evolution.展开更多
Objective:To analyze the identification and typing of bone flaccidity and the law of medication in ancient books based on the Encyclopaedia of TCM(Traditional Chinese Medicine)using the hidden structure model.Methods:...Objective:To analyze the identification and typing of bone flaccidity and the law of medication in ancient books based on the Encyclopaedia of TCM(Traditional Chinese Medicine)using the hidden structure model.Methods:The formulations for bone flaccidity were searched in the Chinese Medical Code(software),based on which an Excel sheet was created to conduct frequency analysis and construct a matrix of high-frequency medications.The high-frequency medications for bone flaccidity were then analyzed using the Latent 5.0 software and a latent structure model.With SPSS Modeler and Latent 5.0 as the main analysis methods,Chinese medications with a frequency>1.00%were investigated using the latent structure model and association rules,and the medication rules in treating bone flaccidity with TCM were dissected based on the data of frequency.Results:A total of 223 TCM prescriptions were included,with 270 extracted TCM and a total medication frequency of 2340 times.Among them are Achyranthis Bidentatae Radix,Poria,Angelicae Sinensis Radix,Eucommiae Cortex,Rehmanniae Radix Praeparata,and Ginseng Radix Et Rhizoma.They were the high-frequency medicines for treating bone flaccidity,and the efficacy of tonifying medicinal,heat-clearing medicinal,and blood activating and stasis-resolving medicinal were high-frequency medicinal categories.Through the analysis of the evidence by formula,it was concluded that spleen-kidney yang deficiency,kidney deficiency and blood stasis,kidney yang deficiency,qi deficiency/qi stagnation and blood stasis,and liver and kidney yin deficiency were the 6 main types of bone flaccidity,which was generally in line with the etiology of bone flaccidity,which was caused by kidney yang deficiency and accompanied by malfunction of the liver and kidneys.In ancient books,the regulation of the kidney is put into an important position.In this study,19 correlative principles for the treatment of bone flaccidity were derived,whose main combinations are Paeoniae Radix Alba-Angelicae Sinensis Radix,Eucommiae Cortex+Poria-Ginseng Radix Et Rhizoma,Dioscoreae Spongiosae Rhizoma+Cuscutae Semen-Eucommiae Cortex.Conclusions:The medication law of bone flaccidity in the Encyclopaedia of TCM mainly shows that it attaches importance to the regulation of tonifying the liver and kidney to strengthen the tendons and bones and emphasizes that the regulation of the 3 Zang–fu organs,namely the kidney,the liver and the spleen,can play an important role in the treatment of bone flaccidity.展开更多
Tuojiang River Basin is a first-class tributary of the upper reaches of the Yangtze River—which is the longest river in China.As phytoplankton are sensitive indicators of trophic changes inwater bodies,characterizing...Tuojiang River Basin is a first-class tributary of the upper reaches of the Yangtze River—which is the longest river in China.As phytoplankton are sensitive indicators of trophic changes inwater bodies,characterizing phytoplankton communities and their growth influencing factors in polluted urban rivers can provide new ideas for pollution control.Here,we used direct microscopic count and environmental DNA(eDNA)metabarcoding methods to investigate phytoplankton community structure in Tuojiang River Basin(Chengdu,Sichuan Province,China).The association between phytoplankton community structure and water environmental factors was evaluated by Mantel analysis.Additional environmental monitoring data were used to pinpoint major factors that influenced phytoplankton growth based on structural equation modeling.At the phylum level,the dominant phytoplankton taxa identified by the conventional microscopic method mainly belonged to Bacillariophyta,Chlorophyta,and Cyanophyta,in contrast with Chlorophyta,Dinophyceae,and Bacillariophyta identified by eDNA metabarcoding.Inα-diversity analysis,eDNA metabarcoding detected greater species diversity and achieved higher precision than the microscopic method.Phytoplankton growth was largely limited by phosphorus based on the nitrogen-to-phosphorus ratios>16:1 in all water samples.Redundancy analysis and structural equation modeling also confirmed that the nitrogen-to-phosphorus ratio was the principal factor influencing phytoplankton growth.The results could be useful for implementing comprehensive management of the river basin environment.It is recommended to control the discharge of point-and surface-source pollutants and the concentration of dissolved oxygen in areas with excessive nutrients(e.g.,Jianyang-Ziyang).Algae monitoring techniques and removal strategies should be improved in 201 Hospital,Hongrihe Bridge and Colmar Town areas.展开更多
Objectives:Teachers are facing unprecedented new challenges leading them to face an increasing number of tasks that are not part of their job,as well as having to cope with the additional skills acquisition that comes...Objectives:Teachers are facing unprecedented new challenges leading them to face an increasing number of tasks that are not part of their job,as well as having to cope with the additional skills acquisition that comes with non-traditional forms of teaching and learning,and increased work pressure leading to an increase in the rate of teachers leaving the profession.Therefore,this study aims to explore the mechanism of the career calling on job burnout through career adaptability and work engagement.Methods:This study conducted a cross-sectional survey of 465 primary and secondary school teachers(PSST)in China's Mainland from the perspective of work adjustment and used structural equation modeling(SEM)to examine the mediating roles of career adaptability and work engagement in the relationship between teachers’career calling and job burnout.Results:The results show that PSSTs are above average in career calling,career adaptability,and work engagement,while job burnout is below average.A significant positive or negative correlation exists between career calling,career adaptability,work engagement,and job burnout.The result of path analysis indicates that career adaptability and work engagement exert an indirect influence on the job burnout of PSST through three paths:namely,the independent intermediary role of career adaptability(EV=−0.144),the independent intermediary role of work engagement(EV=0.172)and the chain intermediary role of the two(EV=0.176).Conclusion:This study emphasizes the importance of career adaptability and work engagement in teacher development in regulating career calling and job burnout.Therefore,on the one hand,we think that if managers want to reduce teachers’job burnout,they need to pay more attention to teachers’career adaptability and work engagement,rather than relying solely on teachers’career calling.On the other hand,it is to remind teachers not to rely on their adjustment to adapt to the work,but also to need outside help as much as possible.展开更多
Porosity is an important attribute for evaluating the petrophysical properties of reservoirs, and has guiding significance for the exploration and development of oil and gas. The seismic inversion is a key method for ...Porosity is an important attribute for evaluating the petrophysical properties of reservoirs, and has guiding significance for the exploration and development of oil and gas. The seismic inversion is a key method for comprehensively obtaining the porosity. Deep learning methods provide an intelligent approach to suppress the ambiguity of the conventional inversion method. However, under the trace-bytrace inversion strategy, there is a lack of constraints from geological structural information, resulting in poor lateral continuity of prediction results. In addition, the heterogeneity and the sedimentary variability of subsurface media also lead to uncertainty in intelligent prediction. To achieve fine prediction of porosity, we consider the lateral continuity and variability and propose an improved structural modeling deep learning porosity prediction method. First, we combine well data, waveform attributes, and structural information as constraints to model geophysical parameters, constructing a high-quality training dataset with sedimentary facies-controlled significance. Subsequently, we introduce a gated axial attention mechanism to enhance the features of dataset and design a bidirectional closed-loop network system constrained by inversion and forward processes. The constraint coefficient is adaptively adjusted by the petrophysical information contained between the porosity and impedance in the study area. We demonstrate the effectiveness of the adaptive coefficient through numerical experiments.Finally, we compare the performance differences between the proposed method and conventional deep learning methods using data from two study areas. The proposed method achieves better consistency with the logging porosity, demonstrating the superiority of the proposed method.展开更多
Controversy is ongoing regarding the relationship between ore formation and the structural evolution of the Hadamengou gold deposit.To address this issue,we conducted a comprehensive investigation of mineralization-re...Controversy is ongoing regarding the relationship between ore formation and the structural evolution of the Hadamengou gold deposit.To address this issue,we conducted a comprehensive investigation of mineralization-related structures,geochronology and Fe isotopes.From the perspective of spatial evolution,hydrothermal fluids originating from the Shadegai and Xishadegai plutons have extracted accumulated ore-forming elements from the Wulashan Group(Ar2WL)and then evolved,initiating at Exploration Line 11 and migrating eastwards and westwards along the EW-trending thrust fault system to form orebodies.From the temporal evolution standpoint,the Wulashan Group(Ar_(2)WL)experienced diagenesis(2591.00 Ma to 2204.00 Ma)and metamorphism(2074.00 Ma to 1625.00 Ma)from late Neoarchean to early Paleoproterozoic,when ore-forming materials were initially accumulated;in the early Paleozoic(440.71 Ma to 425.00 Ma),the collision led to the formation of early-stage EW-trending imbricated thrust faults,which established a fundamental structural framework for the orefield and further accumulated ore-forming materials;from the late Paleozoic to the Mesozoic,multiple subsequent episodes of regional tectonic-magmatic-hydrothermal events have superimposed,modified and reactivated the thrust fault system.Notably,the Triassic period,particularly between 245.00 Ma and 217.90 Ma,is considered to be a primary ore-forming stage.In summary,the intricate relationship between ore-formation and structural evolution has been fundamentally elucidated.展开更多
Background:Resilience is crucial for medical college students to thrive in the highly stressful environment of medical education.However,the prevalence of problematic internet use(PIU)in this population may negatively...Background:Resilience is crucial for medical college students to thrive in the highly stressful environment of medical education.However,the prevalence of problematic internet use(PIU)in this population may negatively impact their resilience.This study investigated the influence of problematic online gaming(PG)and problematic social media use(PSMU)on the resilience of medical college students in China.Methods:A sample of 5075 first-year medical college students from four Chinese universities was studied.PG served as the independent variable,resilience as the dependent variable,fatigue as the mediator,and PSMU as the moderator.Structural equation modeling was conducted using LISREL 8.80.Additionally,a moderated mediation model was evaluated using the jAMM module in jamovi 2.6.13.Results:The study’s findings revealed significant negative correlations between resilience and the variables of PG,PSMU,and fatigue.Fatigue mediated the relationship between PG and resilience(B=−0.04,95%CI=[−0.05,−0.03]).PSMU moderated the direct relationship between PG and resilience with the interaction term PG×PSMU significant(B=−0.004,t=−6.501,p<0.001)and the first stage(PG→fatigue)of the mediation with PG×PSMU significant(B=0.055,t=8.351,p<0.001).The detrimental effects of PG on resilience were more pronounced among individuals with lower levels of PSMU.Conclusion:This study concluded that addressing PIU,particularly PG,is essential for fostering resilience in medical college students.While PSMU itself is maladaptive,the underlying social media engagement may serve a protective role through social support in mitigating the adverse effects of PG on resilience.展开更多
Dentistry is a profession with a high prevalence of work-related musculoskeletal disorders(WMSDs),with symptoms often appearing very early in one’s career[1].WMSDs are conditions affecting the muscles,bones,and nervo...Dentistry is a profession with a high prevalence of work-related musculoskeletal disorders(WMSDs),with symptoms often appearing very early in one’s career[1].WMSDs are conditions affecting the muscles,bones,and nervous system due to occupational factors.In 2002,the International Labor Organization included musculoskeletal diseases in the International List of Occupational Diseases.China’s recently updated Classification and Catalog of Occupational Diseases has introduced two new categories of occupational illnesses,including occupational musculoskeletal disorders.WMSDs significantly impact the health and work of dentists,reducing their quality of life and causing economic losses.These disorders are multifactorial in nature,influenced by personal,psychosocial,biomechanical,and environmental factors.Dentists frequently maintain static or awkward postures during procedures,which leads to musculoskeletal strain and discomfort;additionally,long working hours contribute to psychological stress,further increasing the risk of WMSDs[2].展开更多
Syndrome differentiation is the character of Chinese medicine （CM）. Disease differentiation is the principle of Western medicine （WM）. Identifying basic syndromes feature and structure of disease of WM is an impor...Syndrome differentiation is the character of Chinese medicine （CM）. Disease differentiation is the principle of Western medicine （WM）. Identifying basic syndromes feature and structure of disease of WM is an important avenue for prevention and treatment of integrated Chinese and Western medicine. The idea here is first to divide all patients suffering from a disease of WM into several groups in the light of the stage of the disease, and secondly to identify basic syndromes feature in a distinct stage, and finally to achieve the purpose of syndrome differentiation. Syndrome differentiation is simply taken as a classifier that classifies patients into distinct classes primarily based on overall observation of their symptoms. Previous clustering methods are unable to cope with the complexity of CM. We therefore show a new multi-dimensional clustering method in the form of general latent structure （GLS） model, which is a suitable statistical learning technique of latent class analysis. In this paper, we learn an optimal GLS model which reflects much better model quality compared with other latent class models from the osteoporosis patient of community women （OPCW） real data including 40 65 year old women whose bone mineral density （BMD） is less than mean2.0 standard deviation （M 2.0SD）. Further, we illustrate a case analysis of statistical identification of CM syndromes feature and structure of OPCW from qualitative and quantitative contents through the GLS model. Our analysis has discovered natural clusters and structures that correspond well to CM basic syndrome and factors of osteoporosis patients （OP）. The GLS model suggests the possibility of establishing objective and quantitative diagnosis standards for syndrome differentiation on OPCW. Hence, for the future it can provide a reference for the similar study from the perspective of a combination of disease differentiation and syndrome differentiation.展开更多
It is difficult to solve the structural problems related to agricultural engineering,due to the wide ranges of the means of related variables and complex structural shapes.For these reasons,discrete models are require...It is difficult to solve the structural problems related to agricultural engineering,due to the wide ranges of the means of related variables and complex structural shapes.For these reasons,discrete models are required that are able to replace or simplify solid structure components used in traditional analysis methods.Therefore,the objective of this study was to develop a regular truss structure model that behaves the same way as a solid structure.It was assumed that if a unit element consists of truss elements with each hinge at the end of the element and the size of the element is infinitesimal,the stress distribution and displacement field will be constant throughout the domain of the unit element.Additionally,the behavior of the truss element was assumed to be in a linear state in a two-dimensional plane.The law of energy conservation,based on the theory of elasticity,was applied to determine the equilibrium conditions between discretized and solid elements.The restrictive condition that we obtained revealed that applications are limited to only ideal elastic materials with a Poisson’s ratio of 1 to 3.The volumetric ratio of the equivalent truss to the continuum structures was 3:1,regardless of the size or number of the mesh.To calculate the internal stress and strain of the unit element,the geometric relationships of each truss member,which has its own role against different stress directions,were used.The calculated von Misses stresses were used to verify this model.Stress concentrations,as explained based on Saint Venant’s principle,were also observed in the equivalent truss structure model.The main stress paths,indicating the areas where reinforcement bars should be placed,were successfully shown without the requirement that each element be transformed in the direction of principal stress;this was done by eliminating elements with only compressive and near-zero stresses.展开更多
In this paper, a fluid structure interaction（FSI） model is used to study the internal flow field and the measurement performance of a multi-channel flow meter. The RNG k- ε turbulent model and the finite element mo...In this paper, a fluid structure interaction（FSI） model is used to study the internal flow field and the measurement performance of a multi-channel flow meter. The RNG k- ε turbulent model and the finite element model are used separately in the fluid domain and the structure domain to obtain the meter factor K and the deformation of the structure. The meter factor K of the flow meter is obtained through the FSI model at temperatures of 20 ℃, 50 ℃ and 80 ℃. The calculated results show the thermo expansion of the structure can significantly influence the measurement performance of the flow meter. The meter factor of the flow meter is also measured experimentally, and the comparison between the experimental results and the calculated results shows the validity of the fluid-structure interaction model. In order to reduce the measurement error, the meter factor K should be modified as the water temperature changes.展开更多
基金National Natural Science Foundation of China(22073023)Natural Science Foundation of Henan Province(242300421134)+1 种基金the Young Backbone Teacher in Colleges and Universities of Henan Province(2021GGJS020)Foundation of State Key Laboratory of Antiviral Drugs。
文摘The acetylpolyamine oxidase(APAO),spermine oxidase(SMO),and spermidine/spermine N1-acetyltransferase(SSAT)are pivotal enzymes in polyamine metabolism,exerting direct influence on polyamine homeostasis regulation.Dysfunctions in these enzymes are intricately linked to inflammatory diseases and cancers.Establishing their three-dimensional structures is essential for exploring enzymatic catalytic mechanisms and designing inhibitors at the atomic level.This article primarily assesses the precision of AlphaFold2 and molecular dynamics simulations in determining the three-dimensional structures of these enzymes,utilizing protein conformation rationality assessment,residue correlation matrix,and other techniques.This provides robust models for subsequent polyamine catabolic metabolism calculations and offers valuable insights for modeling proteins that have yet to acquire crystal structures.
文摘As the core content of pragmatic translation teaching research,pragmatic translation skill is closely correlated with translation technique and operation field.Viewed from the current English teaching situation in colleges and universities,translation skill is not cultivated as an independent language competence.Moreover,its research is insufficient.On account of this,the author first gives an introduction to pragmatic translation skill and pragmatic translation skill structure model in this paper.On this basis,the author also analyzes the application of pragmatic translation skill structure model in translation teaching.
基金financial provided by the National Natural Science Foundation of China (Nos. 50474066, 50874108, 51274201, and 51674260)the Coal Joint Fund from National Natural Science Foundation of China and Shenhua Group Corporation Limited (No. U1361116)the National Basic Research Program of China (No. 2012CB214900)
文摘Although human beings have come to understand and utilize coal for a very long history, no theoretical breakthrough in the study of coal structure has been made, which still needs continuous efforts of coal chemical workers. Based on the viewpoint of ‘vague/clear', the species classification and accurate analysis on coal were conducted by using the natural clustering all-component separation method. A more systematic and detailed coal embedded structure model theory which is suitable for coal of all ranks was developed from the previous one and a more complete theoretical system about the component and structure of coal was constructed. The whole establishment process of the theory was summarized and some of the main support data and analysis test results, including TEM, AFM, FTIR, GC/MS, MALDI/TOF/MS, DART/MSD, fractal analysis and so on were provided. The coal embedded structure theory fully considers both the identity and the particularity of all-rank coal, reflects the coal component and structure in the full range of coal rank, solves the systematic cognitive problem of coal component and structure on macro and micro level, and provides a valuable and meaningful theoretical approach for the coal processing and conversion technology.
基金provided by the Talent Training Project of the National Natural Science Foundation of China (No.J0730534)the National Natural Science Foundation of China (No.40902093)+1 种基金the Morning Light Plan of the Shanghai Educational Development Foundation (No.2007CG34)the Open Foundation of the Shanghai Key Laboratory of Urbanization and Ecological Restoration (No.200803)
文摘Uncertainty in 3D geological structure models has become a bottleneck that restricts the development and application of 3D geological modeling.In order to solve this problem during periods of accuracy assessment,error detection and dynamic correction in 3D geological structure models,we have reviewed the current situation and development trends in 3D geological modeling.The main context of uncertainty in 3D geological structure models is discussed.Major research issues and a general framework system of uncertainty in 3D geological structure models are proposed.We have described in detail the integration of development practices of 3D geological modeling systems,as well as the implementation process for uncertainty evaluation in 3D geological structure models.This study has laid the basis to build theoretical and methodological systems for accuracy assessment and error correction in 3D geological models and can assist in improving 3D modeling techniques under complex geological conditions.
文摘When Kalman filter is used in the estimation of Vasicek term structure of interest rates,it is usual to assume that the measurement noise is uncorrelated.Study results are more favorable to the assumption of correlated measurement noise.An augmented state Kalman filter form for Vasicek model is proposed to optimally estimate the unobservable state variable with the assumption of correlated measurement noise.Empirical results indicate that the model with sequentially correlated measurement noise can more accurately describe the dynamics of the term structure of interest rates.
基金Item Sponsored by National Natural Science Foundation of China(51174253)
文摘Structure model of granules, boundary value of nucleus and powder, and the relationship between granula- tion efficiency and boundary value were investigated. Granules of sintering mixtures are composed of adhesive powder and nucleus. In the mixtures, particles larger than 1.00 mm act as nucleus and particles smaller than 0.25 mm act as adhesive powder. Particles with size between 0.25--1.00 mm can be adhesive powder as well as nucleus depending on the granulation conditions. When the boundary value is close to 0.25 mm, the granulation efficiency is lower than 50%. When the boundary value is close to 1.00 mm, the granulation efficiency is above 90%. The boundary value is influenced by the iron ore type, granulation moisture, fineness of raw materials and burnt-lime activity. Good adhe- sive capability, suitable moisture content, appropriate particle size distribution and high burnt-lime activity make the boundary value move towards 1.00 mm and improve the granulation efficiency.
基金supported by the National Natural Science Foundation of China(Grant No.11975307).
文摘Accurate identification of influential nodes facilitates the control of rumor propagation and interrupts the spread of computer viruses.Many classical approaches have been proposed by researchers regarding different aspects.To explore the impact of location information in depth,this paper proposes an improved global structure model to characterize the influence of nodes.The method considers both the node’s self-information and the role of the location information of neighboring nodes.First,degree centrality of each node is calculated,and then degree value of each node is used to represent self-influence,and degree values of the neighbor layer nodes are divided by the power of the path length,which is path attenuation used to represent global influence.Finally,an extended improved global structure model that considers the nearest neighbor information after combining self-influence and global influence is proposed to identify influential nodes.In this paper,the propagation process of a real network is obtained by simulation with the SIR model,and the effectiveness of the proposed method is verified from two aspects of discrimination and accuracy.The experimental results show that the proposed method is more accurate in identifying influential nodes than other comparative methods with multiple networks.
基金Supported by the National Natural Science Foundation of China(61303214)the Science and Technology Project of China State Grid Corp(KJ15-1-32)
文摘In order to solve the problem that the embedded software has the shortcoming of the platform dependence, this paper presents an embedded software analysis method based on the static structure model. Before control flow and data flow analysis, a lexical analysis/syntax analysis method with simplified grammar and sentence depth is designed to analyze the embedded software. The experiments use the open source code of smart meters as a case, and the artificial faults as the test objects, repeating 30 times. Compared with the popular static analyzing tools PC-Lint and Splint, the method can accurately orient 91% faults, which is between PC-Lint＇s 95% and Splint＇s 85%. The result indicates that the correct rate of our method is acceptable. Meanwhile, by removing the platform-dependent operation with simplified syntax analysis, our method is independent of development environment. It also shows that the method is applicable to the compiled C（including embedded software） program.
文摘. In this article, we describe the characteristics of large-scale modeling of the theme text of this site data and important progress in recent years. Topic modeling approach has attracted wide interest in the world, and promote a number of important data mining, development of computer vision and computational biology applications, including automatic text summaries, information retrieval, information recommendation, topic detection and tracking, natural scene understanding human action recognition and gene expression analysis. The main features of the model and the corresponding theme paper focuses on the text of this site data. Data with dynamic, high-end, multi-channel and distributed structure and the structure of the model is only part of the theme before modeling. The paper discussed in the framework of the unity of the three-dimensional Markov model of four structural features of the text of this site data modeling, and analysis of distributed computing and word combination of three-dimensional modeling topics Markov model and type fuzzy systems the possibility of applications. In addition to structural modeling for this site text data, also we discuss some of the three-dimensional Markov model energy minimization of machine learning algorithms.
文摘A structure model of urban traffic system evolution is built based on the analysis of the factors influencing the system evolution and the hierarchy between the factors. Then the influencing degrees of the factors are quantificationally analyzed by DEMATE （decision making trial and evaluation laboratory）. The analysis results indicate that the traffic mode structure which achieves the highest central degree is the dominant influencing factor of the urban traffic system evolution, and that economy development and the traffic policy are the second important factors that also affect the Waffle mode structures. Furthermore, physical geography is a basic restriction to the urban traffic system evolution.
基金supported by China Academy of Chinese Medical Science and Technology Innovation Project Heidihuang Pill Major Research Project(No.CI2021A00606)China Academy of Chinese Medical Sciences Self-selected projects(YZX202237,YZX202241,YZX202246,YZ2020042,YZ202225,YZ2020019)Beijing Traditional TCM Science and Technology Development Fund Project(No.JJ2018-99).
文摘Objective:To analyze the identification and typing of bone flaccidity and the law of medication in ancient books based on the Encyclopaedia of TCM(Traditional Chinese Medicine)using the hidden structure model.Methods:The formulations for bone flaccidity were searched in the Chinese Medical Code(software),based on which an Excel sheet was created to conduct frequency analysis and construct a matrix of high-frequency medications.The high-frequency medications for bone flaccidity were then analyzed using the Latent 5.0 software and a latent structure model.With SPSS Modeler and Latent 5.0 as the main analysis methods,Chinese medications with a frequency>1.00%were investigated using the latent structure model and association rules,and the medication rules in treating bone flaccidity with TCM were dissected based on the data of frequency.Results:A total of 223 TCM prescriptions were included,with 270 extracted TCM and a total medication frequency of 2340 times.Among them are Achyranthis Bidentatae Radix,Poria,Angelicae Sinensis Radix,Eucommiae Cortex,Rehmanniae Radix Praeparata,and Ginseng Radix Et Rhizoma.They were the high-frequency medicines for treating bone flaccidity,and the efficacy of tonifying medicinal,heat-clearing medicinal,and blood activating and stasis-resolving medicinal were high-frequency medicinal categories.Through the analysis of the evidence by formula,it was concluded that spleen-kidney yang deficiency,kidney deficiency and blood stasis,kidney yang deficiency,qi deficiency/qi stagnation and blood stasis,and liver and kidney yin deficiency were the 6 main types of bone flaccidity,which was generally in line with the etiology of bone flaccidity,which was caused by kidney yang deficiency and accompanied by malfunction of the liver and kidneys.In ancient books,the regulation of the kidney is put into an important position.In this study,19 correlative principles for the treatment of bone flaccidity were derived,whose main combinations are Paeoniae Radix Alba-Angelicae Sinensis Radix,Eucommiae Cortex+Poria-Ginseng Radix Et Rhizoma,Dioscoreae Spongiosae Rhizoma+Cuscutae Semen-Eucommiae Cortex.Conclusions:The medication law of bone flaccidity in the Encyclopaedia of TCM mainly shows that it attaches importance to the regulation of tonifying the liver and kidney to strengthen the tendons and bones and emphasizes that the regulation of the 3 Zang–fu organs,namely the kidney,the liver and the spleen,can play an important role in the treatment of bone flaccidity.
基金supported by the National Natural Science Foundation of China (No.72091511)the Science Fund for Distinguished Young Scholars of Hebei Province (No.E2022402064).
文摘Tuojiang River Basin is a first-class tributary of the upper reaches of the Yangtze River—which is the longest river in China.As phytoplankton are sensitive indicators of trophic changes inwater bodies,characterizing phytoplankton communities and their growth influencing factors in polluted urban rivers can provide new ideas for pollution control.Here,we used direct microscopic count and environmental DNA(eDNA)metabarcoding methods to investigate phytoplankton community structure in Tuojiang River Basin(Chengdu,Sichuan Province,China).The association between phytoplankton community structure and water environmental factors was evaluated by Mantel analysis.Additional environmental monitoring data were used to pinpoint major factors that influenced phytoplankton growth based on structural equation modeling.At the phylum level,the dominant phytoplankton taxa identified by the conventional microscopic method mainly belonged to Bacillariophyta,Chlorophyta,and Cyanophyta,in contrast with Chlorophyta,Dinophyceae,and Bacillariophyta identified by eDNA metabarcoding.Inα-diversity analysis,eDNA metabarcoding detected greater species diversity and achieved higher precision than the microscopic method.Phytoplankton growth was largely limited by phosphorus based on the nitrogen-to-phosphorus ratios>16:1 in all water samples.Redundancy analysis and structural equation modeling also confirmed that the nitrogen-to-phosphorus ratio was the principal factor influencing phytoplankton growth.The results could be useful for implementing comprehensive management of the river basin environment.It is recommended to control the discharge of point-and surface-source pollutants and the concentration of dissolved oxygen in areas with excessive nutrients(e.g.,Jianyang-Ziyang).Algae monitoring techniques and removal strategies should be improved in 201 Hospital,Hongrihe Bridge and Colmar Town areas.
基金funded by Humanities and Social Sciences Foundation and Natural Science Foundation of Nanjing University of Posts and Telecommunications(NYY222055,NY224176)General Subject of Educational Science Planning in Jiangsu Province(C/2024/01/76)National Natural Science Foundation of China(62307025).
文摘Objectives:Teachers are facing unprecedented new challenges leading them to face an increasing number of tasks that are not part of their job,as well as having to cope with the additional skills acquisition that comes with non-traditional forms of teaching and learning,and increased work pressure leading to an increase in the rate of teachers leaving the profession.Therefore,this study aims to explore the mechanism of the career calling on job burnout through career adaptability and work engagement.Methods:This study conducted a cross-sectional survey of 465 primary and secondary school teachers(PSST)in China's Mainland from the perspective of work adjustment and used structural equation modeling(SEM)to examine the mediating roles of career adaptability and work engagement in the relationship between teachers’career calling and job burnout.Results:The results show that PSSTs are above average in career calling,career adaptability,and work engagement,while job burnout is below average.A significant positive or negative correlation exists between career calling,career adaptability,work engagement,and job burnout.The result of path analysis indicates that career adaptability and work engagement exert an indirect influence on the job burnout of PSST through three paths:namely,the independent intermediary role of career adaptability(EV=−0.144),the independent intermediary role of work engagement(EV=0.172)and the chain intermediary role of the two(EV=0.176).Conclusion:This study emphasizes the importance of career adaptability and work engagement in teacher development in regulating career calling and job burnout.Therefore,on the one hand,we think that if managers want to reduce teachers’job burnout,they need to pay more attention to teachers’career adaptability and work engagement,rather than relying solely on teachers’career calling.On the other hand,it is to remind teachers not to rely on their adjustment to adapt to the work,but also to need outside help as much as possible.
基金the support of Research Program of Fine Exploration and Surrounding Rock Classification Technology for Deep Buried Long Tunnels Driven by Horizontal Directional Drilling and Magnetotelluric Methods Based on Deep Learning under Grant E202408010the Sichuan Science and Technology Program under Grant 2024NSFSC1984 and Grant 2024NSFSC1990。
文摘Porosity is an important attribute for evaluating the petrophysical properties of reservoirs, and has guiding significance for the exploration and development of oil and gas. The seismic inversion is a key method for comprehensively obtaining the porosity. Deep learning methods provide an intelligent approach to suppress the ambiguity of the conventional inversion method. However, under the trace-bytrace inversion strategy, there is a lack of constraints from geological structural information, resulting in poor lateral continuity of prediction results. In addition, the heterogeneity and the sedimentary variability of subsurface media also lead to uncertainty in intelligent prediction. To achieve fine prediction of porosity, we consider the lateral continuity and variability and propose an improved structural modeling deep learning porosity prediction method. First, we combine well data, waveform attributes, and structural information as constraints to model geophysical parameters, constructing a high-quality training dataset with sedimentary facies-controlled significance. Subsequently, we introduce a gated axial attention mechanism to enhance the features of dataset and design a bidirectional closed-loop network system constrained by inversion and forward processes. The constraint coefficient is adaptively adjusted by the petrophysical information contained between the porosity and impedance in the study area. We demonstrate the effectiveness of the adaptive coefficient through numerical experiments.Finally, we compare the performance differences between the proposed method and conventional deep learning methods using data from two study areas. The proposed method achieves better consistency with the logging porosity, demonstrating the superiority of the proposed method.
基金the financial support by the Major Research Plan of National Natural Science Foundation of China(92062219)the Young Elite Scientists Sponsorship Program by BAST(No.BYESS2023411)+2 种基金the Open Research Project from the State Key Laboratory of Geological Processes and Mineral Resources,China University of Geosciences(GPMR202407)the Geological Survey Project of the China Geological Survey„General survey of Hadamengou Rock Gold Deposit in Inner Mongolia'(DD20191017)the Geological Survey Project(H90063).
文摘Controversy is ongoing regarding the relationship between ore formation and the structural evolution of the Hadamengou gold deposit.To address this issue,we conducted a comprehensive investigation of mineralization-related structures,geochronology and Fe isotopes.From the perspective of spatial evolution,hydrothermal fluids originating from the Shadegai and Xishadegai plutons have extracted accumulated ore-forming elements from the Wulashan Group(Ar2WL)and then evolved,initiating at Exploration Line 11 and migrating eastwards and westwards along the EW-trending thrust fault system to form orebodies.From the temporal evolution standpoint,the Wulashan Group(Ar_(2)WL)experienced diagenesis(2591.00 Ma to 2204.00 Ma)and metamorphism(2074.00 Ma to 1625.00 Ma)from late Neoarchean to early Paleoproterozoic,when ore-forming materials were initially accumulated;in the early Paleozoic(440.71 Ma to 425.00 Ma),the collision led to the formation of early-stage EW-trending imbricated thrust faults,which established a fundamental structural framework for the orefield and further accumulated ore-forming materials;from the late Paleozoic to the Mesozoic,multiple subsequent episodes of regional tectonic-magmatic-hydrothermal events have superimposed,modified and reactivated the thrust fault system.Notably,the Triassic period,particularly between 245.00 Ma and 217.90 Ma,is considered to be a primary ore-forming stage.In summary,the intricate relationship between ore-formation and structural evolution has been fundamentally elucidated.
基金supported by General Education Project of the National Social Science Foundation in 2020:“Multi-Dimensional Reconstruction of Peer Review Mechanisms in the Evaluation of Scientific and Technological Talents in Universities(BIA200167).”。
文摘Background:Resilience is crucial for medical college students to thrive in the highly stressful environment of medical education.However,the prevalence of problematic internet use(PIU)in this population may negatively impact their resilience.This study investigated the influence of problematic online gaming(PG)and problematic social media use(PSMU)on the resilience of medical college students in China.Methods:A sample of 5075 first-year medical college students from four Chinese universities was studied.PG served as the independent variable,resilience as the dependent variable,fatigue as the mediator,and PSMU as the moderator.Structural equation modeling was conducted using LISREL 8.80.Additionally,a moderated mediation model was evaluated using the jAMM module in jamovi 2.6.13.Results:The study’s findings revealed significant negative correlations between resilience and the variables of PG,PSMU,and fatigue.Fatigue mediated the relationship between PG and resilience(B=−0.04,95%CI=[−0.05,−0.03]).PSMU moderated the direct relationship between PG and resilience with the interaction term PG×PSMU significant(B=−0.004,t=−6.501,p<0.001)and the first stage(PG→fatigue)of the mediation with PG×PSMU significant(B=0.055,t=8.351,p<0.001).The detrimental effects of PG on resilience were more pronounced among individuals with lower levels of PSMU.Conclusion:This study concluded that addressing PIU,particularly PG,is essential for fostering resilience in medical college students.While PSMU itself is maladaptive,the underlying social media engagement may serve a protective role through social support in mitigating the adverse effects of PG on resilience.
基金supported by the 2021 Shandong Province Higher Education Institutions“Youth Innovation Talent Introduction and Cultivation Plan”(Public Health Safety Risk Assessment and Response Innovation Team)National Traditional Chinese Medicine Comprehensive Reform Demonstration Zone Science and Technology Co construction Project(No.GZYKJSSD-2024-106)Research Project of Shandong Educational Supervision Society(No.SDJYDDXH2023-2159).
文摘Dentistry is a profession with a high prevalence of work-related musculoskeletal disorders(WMSDs),with symptoms often appearing very early in one’s career[1].WMSDs are conditions affecting the muscles,bones,and nervous system due to occupational factors.In 2002,the International Labor Organization included musculoskeletal diseases in the International List of Occupational Diseases.China’s recently updated Classification and Catalog of Occupational Diseases has introduced two new categories of occupational illnesses,including occupational musculoskeletal disorders.WMSDs significantly impact the health and work of dentists,reducing their quality of life and causing economic losses.These disorders are multifactorial in nature,influenced by personal,psychosocial,biomechanical,and environmental factors.Dentists frequently maintain static or awkward postures during procedures,which leads to musculoskeletal strain and discomfort;additionally,long working hours contribute to psychological stress,further increasing the risk of WMSDs[2].
基金Supported by Items of Institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences Natural Science Fundation(No.30873339)
文摘Syndrome differentiation is the character of Chinese medicine （CM）. Disease differentiation is the principle of Western medicine （WM）. Identifying basic syndromes feature and structure of disease of WM is an important avenue for prevention and treatment of integrated Chinese and Western medicine. The idea here is first to divide all patients suffering from a disease of WM into several groups in the light of the stage of the disease, and secondly to identify basic syndromes feature in a distinct stage, and finally to achieve the purpose of syndrome differentiation. Syndrome differentiation is simply taken as a classifier that classifies patients into distinct classes primarily based on overall observation of their symptoms. Previous clustering methods are unable to cope with the complexity of CM. We therefore show a new multi-dimensional clustering method in the form of general latent structure （GLS） model, which is a suitable statistical learning technique of latent class analysis. In this paper, we learn an optimal GLS model which reflects much better model quality compared with other latent class models from the osteoporosis patient of community women （OPCW） real data including 40 65 year old women whose bone mineral density （BMD） is less than mean2.0 standard deviation （M 2.0SD）. Further, we illustrate a case analysis of statistical identification of CM syndromes feature and structure of OPCW from qualitative and quantitative contents through the GLS model. Our analysis has discovered natural clusters and structures that correspond well to CM basic syndrome and factors of osteoporosis patients （OP）. The GLS model suggests the possibility of establishing objective and quantitative diagnosis standards for syndrome differentiation on OPCW. Hence, for the future it can provide a reference for the similar study from the perspective of a combination of disease differentiation and syndrome differentiation.
基金We acknowledge that this work was supported by the research grant of Chungbuk National University in 2013.
文摘It is difficult to solve the structural problems related to agricultural engineering,due to the wide ranges of the means of related variables and complex structural shapes.For these reasons,discrete models are required that are able to replace or simplify solid structure components used in traditional analysis methods.Therefore,the objective of this study was to develop a regular truss structure model that behaves the same way as a solid structure.It was assumed that if a unit element consists of truss elements with each hinge at the end of the element and the size of the element is infinitesimal,the stress distribution and displacement field will be constant throughout the domain of the unit element.Additionally,the behavior of the truss element was assumed to be in a linear state in a two-dimensional plane.The law of energy conservation,based on the theory of elasticity,was applied to determine the equilibrium conditions between discretized and solid elements.The restrictive condition that we obtained revealed that applications are limited to only ideal elastic materials with a Poisson’s ratio of 1 to 3.The volumetric ratio of the equivalent truss to the continuum structures was 3:1,regardless of the size or number of the mesh.To calculate the internal stress and strain of the unit element,the geometric relationships of each truss member,which has its own role against different stress directions,were used.The calculated von Misses stresses were used to verify this model.Stress concentrations,as explained based on Saint Venant’s principle,were also observed in the equivalent truss structure model.The main stress paths,indicating the areas where reinforcement bars should be placed,were successfully shown without the requirement that each element be transformed in the direction of principal stress;this was done by eliminating elements with only compressive and near-zero stresses.
基金Project supported by the Natural Science Foundation of Shandong Province(Grant No.ZR2014EEM015)
文摘In this paper, a fluid structure interaction（FSI） model is used to study the internal flow field and the measurement performance of a multi-channel flow meter. The RNG k- ε turbulent model and the finite element model are used separately in the fluid domain and the structure domain to obtain the meter factor K and the deformation of the structure. The meter factor K of the flow meter is obtained through the FSI model at temperatures of 20 ℃, 50 ℃ and 80 ℃. The calculated results show the thermo expansion of the structure can significantly influence the measurement performance of the flow meter. The meter factor of the flow meter is also measured experimentally, and the comparison between the experimental results and the calculated results shows the validity of the fluid-structure interaction model. In order to reduce the measurement error, the meter factor K should be modified as the water temperature changes.
