AIM:To build a functional generalized estimating equation(GEE)model to detect glaucomatous visual field progression and compare the performance of the proposed method with that of commonly employed algorithms.METHODS:...AIM:To build a functional generalized estimating equation(GEE)model to detect glaucomatous visual field progression and compare the performance of the proposed method with that of commonly employed algorithms.METHODS:Totally 716 eyes of 716 patients with primary open angle glaucoma(POAG)with at least 5 reliable 24-2 test results and 2y of follow-up were selected.The functional GEE model was used to detect perimetric progression in the training dataset(501 eyes).In the testing dataset(215 eyes),progression was evaluated the functional GEE model,mean deviation(MD)and visual field index(VFI)rates of change,Advanced Glaucoma Intervention Study(AGIS)and Collaborative Initial Glaucoma Treatment Study(CIGTS)scores,and pointwise linear regression(PLR).RESULTS:The proposed method showed the highest proportion of eyes detected as progression(54.4%),followed by the VFI rate(34.4%),PLR(23.3%),and MD rate(21.4%).The CIGTS and AGIS scores had a lower proportion of eyes detected as progression(7.9%and 5.1%,respectively).The time to detection of progression was significantly shorter for the proposed method than that of other algorithms(adjusted P≤0.019).The VFI rate displayed moderate pairwise agreement with the proposed method(k=0.47).CONCLUSION:The functional GEE model shows the highest proportion of eyes detected as perimetric progression and the shortest time to detect perimetric progression in patients with POAG.展开更多
Owing to intensified globalization and informatization,the structures of the urban scale hierarchy and urban networks between cities have become increasingly intertwined,resulting in different spatial effects.Therefor...Owing to intensified globalization and informatization,the structures of the urban scale hierarchy and urban networks between cities have become increasingly intertwined,resulting in different spatial effects.Therefore,this paper analyzes the spatial interaction between urban scale hierarchy and urban networks in China from 2019 to 2023,drawing on Baidu migration data and employing a spatial simultaneous equation model.The results reveal a significant positive spatial correlation between cities with higher hierarchy and those with greater network centrality.Within a static framework,we identify a positive interaction between urban scale hierarchy and urban network centrality,while their spatial cross-effects manifest as negative neighborhood interactions based on geographical distance and positive cross-scale interactions shaped by network connections.Within a dynamic framework,changes in urban scale hierarchy and urban networks are mutually reinforcing,thereby widening disparities within the urban hierarchy.Furthermore,an increase in a city’s network centrality had a dampening effect on the population growth of neighboring cities and network-connected cities.This study enhances understanding of the spatial organisation of urban systems and offers insights for coordinated regional development.展开更多
Dentistry is a profession with a high prevalence of work-related musculoskeletal disorders(WMSDs),with symptoms often appearing very early in one’s career[1].WMSDs are conditions affecting the muscles,bones,and nervo...Dentistry is a profession with a high prevalence of work-related musculoskeletal disorders(WMSDs),with symptoms often appearing very early in one’s career[1].WMSDs are conditions affecting the muscles,bones,and nervous system due to occupational factors.In 2002,the International Labor Organization included musculoskeletal diseases in the International List of Occupational Diseases.China’s recently updated Classification and Catalog of Occupational Diseases has introduced two new categories of occupational illnesses,including occupational musculoskeletal disorders.WMSDs significantly impact the health and work of dentists,reducing their quality of life and causing economic losses.These disorders are multifactorial in nature,influenced by personal,psychosocial,biomechanical,and environmental factors.Dentists frequently maintain static or awkward postures during procedures,which leads to musculoskeletal strain and discomfort;additionally,long working hours contribute to psychological stress,further increasing the risk of WMSDs[2].展开更多
Fractional differential equations(FDEs)provide a powerful tool for modeling systems with memory and non-local effects,but understanding their underlying structure remains a significant challenge.While numerous numeric...Fractional differential equations(FDEs)provide a powerful tool for modeling systems with memory and non-local effects,but understanding their underlying structure remains a significant challenge.While numerous numerical and semi-analytical methods exist to find solutions,new approaches are needed to analyze the intrinsic properties of the FDEs themselves.This paper introduces a novel computational framework for the structural analysis of FDEs involving iterated Caputo derivatives.The methodology is based on a transformation that recasts the original FDE into an equivalent higher-order form,represented as the sum of a closed-form,integer-order component G(y)and a residual fractional power seriesΨ(x).This transformed FDE is subsequently reduced to a first-order ordinary differential equation(ODE).The primary novelty of the proposed methodology lies in treating the structure of the integer-order component G(y)not as fixed,but as a parameterizable polynomial whose coefficients can be determined via global optimization.Using particle swarm optimization,the framework identifies an optimal ODE architecture by minimizing a dual objective that balances solution accuracy against a high-fidelity reference and the magnitude of the truncated residual series.The effectiveness of the approach is demonstrated on both a linear FDE and a nonlinear fractional Riccati equation.Results demonstrate that the framework successfully identifies an optimal,low-degree polynomial ODE architecture that is not necessarily identical to the forcing function of the original FDE.This work provides a new tool for analyzing the underlying structure of FDEs and gaining deeper insights into the interplay between local and non-local dynamics in fractional systems.展开更多
A households′production behavior directly influences the quality of the environment and determines the successful development of nature reserves.Meanwhile,the households′production behaviors are complicated by inter...A households′production behavior directly influences the quality of the environment and determines the successful development of nature reserves.Meanwhile,the households′production behaviors are complicated by interrelated factors,such as protection attitudes,resource endowment,and family wealth.This research evaluated households near the Crested Ibis National Nature Reserve in Shaanxi Province,acquiring data from 436 households around Yang County and Ningshan County in the south slope of Qinling Mountains,China.Based on the collected data,we developed a structural equation model to evaluate the coupling relationships among households′ protection attitudes,production behaviors,resource endowment,and family wealth.The results showed that:1) households with great resource endowment had more negative attitudes,probably due to their greater protection costs;2) the households with higher education levels had worse protection attitudes;3) the households with more family wealth were likely to use fewer fertilizers,pesticides,and firewood;4) the households with more resource endowment showed less production and management behaviors;5) the enhancement of households' attitudes improved production behaviors to protection the environment,but the effects were not statistically significant.Our results provide a basis for the government's protection policy making,exploring the effective management measures that are beneficial for both nature reserve management and community development.展开更多
Work injuries in mines are complex and generally characterized by several factors starting from personal to technical and technical to social characteristics.In this paper,investigation was made through the applicatio...Work injuries in mines are complex and generally characterized by several factors starting from personal to technical and technical to social characteristics.In this paper,investigation was made through the application of structural equation modeling to study the nature of relationships between the influencing/associating personal factors and work injury and their sequential relationships leading towards work injury occurrences in underground coal mines.Six variables namely,rebelliousness,negative affectivity,job boredom,job dissatisfaction and work injury were considered in this study.Instruments were developed to quantify them through a questionnaire survey.Underground mine workers were randomly selected for the survey.Responses from 300 participants were used for the analysis.The structural model of LISREL was used to estimate the interrelationships amongst the variables.The case study results show that negative affectivity and job boredom induce more job dissatisfaction to the workers whereas risk taking attitude of the individual is positively influenced by job dissatisfaction as well as by rebelliousness characteristics of the individual.Finally,risk taking and job dissatisfaction are having positive significant direct relationship with work injury.The findings of this study clearly reveal that rebelliousness,negative affectivity and job boredom are the three key personal factors influencing work related injuries in mines that need to be addressed properly through effective safety programs.展开更多
Purpose:This paper aims to examine how the adoption decision of the internet banking in North Cyprus would be affected based on the following dimensions;the technology features,the personal characteristics,the social ...Purpose:This paper aims to examine how the adoption decision of the internet banking in North Cyprus would be affected based on the following dimensions;the technology features,the personal characteristics,the social environment and the expected risk.Design/methodology/approach:A self-administered survey was conducted with 291 participants responded to it.The partial least square approach of the structural equation modeling(PLS-SEM)is employed to investigate the direct effects of the proposed factors on the adoption decision.Additionally,the mediation test is used to examine indirect effects.Findings:Results showed that even though the participants appreciated the benefits of the online banking as the perceived usefulness factor exerts the greatest direct effect,they would rather use clear and easy-to-use websites,adding to that their assessments of the usefulness of these services are significantly influenced by the surrounding people’s views and prior experience.This is demonstrated by the total effects of the perceived ease of use and the subjective norm factors,which are greater than the direct effect of the perceived usefulness factor since both of these factors have significant direct and indirect effects mediated by the perceived usefulness factor.The negative impact of the perceived risk factor is weak compared to the previous factors.While the personal innovativeness factor showed the weakest effect among the proposed factors.展开更多
This study aimed to construct a quality management model for phase I clinical drug trials.A cross-sectional survey was conducted and data were collected from 604 respondents at 69 institutions in China engaged in phas...This study aimed to construct a quality management model for phase I clinical drug trials.A cross-sectional survey was conducted and data were collected from 604 respondents at 69 institutions in China engaged in phase I clinical drug trials.Exploratory and confirmatory factor analyses were used to develop the survey tool.Structural equation modeling was used to construct a quality management model for phase I clinical drug trials.The results showed that the final survey tool had good reliability and validity(Cronbach’sα=0.938,root mean square error of approximation=0.074,comparative fit index=0.962,and Tucker—Lewis index=0.955).The model included five dimensions:government regulation,industry management,medical institution management,research team management,and contract research organization(CRO)management.In total,22 measurement items were obtained.The structural equation model indicated government regulation,industry management,medical institution management,and CRO management significantly affected the quality of phase I clinical drug trials(β=0.195,β=0.331,β=0.279,andβ=−0.267,respectively;P<0.05).Research team management had no effect on the quality of trials(β=0.041,P=0.610).In conclusion,the model is valuable for identifying factors influencing phase I clinical drug trials and guiding quality management practices.展开更多
This paper describes a structural equation modeling （SEM） analysis of factors influencing architects＇ trust in project design teams. We undertook a survey of architects, during which we distributed 193 questionnair...This paper describes a structural equation modeling （SEM） analysis of factors influencing architects＇ trust in project design teams. We undertook a survey of architects, during which we distributed 193 questionnaires in 29 A-level architectural design institutes selected radomly from the altogether 59 ones in Shenzhen, P. R. China, and received 130 valid questionnaires. We used Amos 6.0 for SEM to identify significant personal construct based factors affecting interpersonal trust. The results show that only social interaction between architects significantly affects their interpersonal trust. The explained variance of trus~ is not very high in the model. Therefore, future research should add more factors into the current model. The practical implication is that team managers should promote the social interactions between team members such that the interpersonal trust level between team members can be improved.展开更多
Structural Equation Modeling （SEM） used widely in sociology, economics and psychology is adopted. Based on data obtained from marketing research, and using statistical analysis software SPSSll. 0 and LISRELS. 7, The...Structural Equation Modeling （SEM） used widely in sociology, economics and psychology is adopted. Based on data obtained from marketing research, and using statistical analysis software SPSSll. 0 and LISRELS. 7, Theory of Five Dimensions of service quality is proved to be suitable in sportswear retailing in China. It analyzes the relationship among five dimensions and puts them in order of importance as to service quality in sportswear retailing. Advices are given for sportswear retail companies to improve their .Service quality and enhance customer loyalty.展开更多
The structural equation model (SEM) concept is generally influenced by the presence of outliers and controlling variables. To a very large extent, this could have consequential effects on the parameters and the model ...The structural equation model (SEM) concept is generally influenced by the presence of outliers and controlling variables. To a very large extent, this could have consequential effects on the parameters and the model fitness. Though previous researches have studied outliers and controlling observations from various perspectives including the use of box plots, normal probability plots, among others, the use of uniform horizontal QQ plot is yet to be explored. This study is, therefore, aimed at applying uniform QQ plots to identifying outliers and possible controlling observations in SEM. The results showed that all the three methods of estimators manifest the ability to identify outliers and possible controlling observations in SEM. It was noted that the Anderson-Rubin estimator of QQ plot showed a more efficient or visual display of spotting outliers and possible controlling observations as compared to the other methods of estimators. Therefore, this paper provides an efficient way identifying outliers as it fragments the data set.展开更多
Taking the second member of the Xujiahe Formation of the Upper Triassic in the Xinchang structural belt as an example,based on data such as logging,production,seismic interpretation and test,a systematic analysis was ...Taking the second member of the Xujiahe Formation of the Upper Triassic in the Xinchang structural belt as an example,based on data such as logging,production,seismic interpretation and test,a systematic analysis was conducted on the structural characteristics and evolution,reservoir diagenesis and densification processes,and types and stages of faults/fractures,and revealing the multi-stage and multi-factor dynamic coupled enrichment mechanisms of tight gas reservoirs.(1)In the early Yanshan period,the paleo-structural traps were formed with low-medium maturity hydrocarbons accumulating in structural highs driven by buoyancy since reservoirs were not fully densified in this stage,demonstrating paleo-structure control on traps and early hydrocarbon accumulation.(2)In the middle-late Yanshan period,the source rocks became mature to generate and expel a large quantity of hydrocarbons.Grain size and type of sandstone controlled the time of reservoir densification,which restricted the scale of hydrocarbon charging,allowing for only a small-scale migration through sand bodies near the fault/fracture or less-densified matrix reservoirs.(3)During the Himalayan period,the source rocks reached overmaturity,and the residual oil cracking gas was efficiently transported along the late-stage faults/fractures.Wells with high production capacity were mainly located in Type I and II fault/fracture zones comprising the late-stage north-south trending fourth-order faults and the late-stage fractures.The productivity of the wells was controlled by the transformation of the late-stage faults/fractures.(4)The Xinchang structural belt underwent three stages of tectonic evolution,two stages of reservoir formation,and three stages of fault/fractures development.Hydrocarbons mainly accumulated in the paleo-structure highs.After reservoir densification and late fault/fracture adjustment,a complex gas-water distribution pattern was formed.Thus,it is summarized as the model of“near-source and low-abundance hydrocarbon charging in the early stage,and differential enrichment of natural gas under the joint control of fault-fold-fracture complex,high-quality reservoirs and structural highs in the late stage”.Faults/fractures with well-coupled fault-fold-fracture-pore are favorable exploration targets with high exploration effectiveness.展开更多
Bayesian networks （BN） have many advantages over other methods in ecological modeling, and have become an increasingly popular modeling tool. However, BN are flawed in regard to building models based on inadequate e...Bayesian networks （BN） have many advantages over other methods in ecological modeling, and have become an increasingly popular modeling tool. However, BN are flawed in regard to building models based on inadequate existing knowledge. To overcome this limitation, we propose a new method that links BN with structural equation modeling （SEM）. In this method, SEM is used to improve the model structure for BN. This method was used to simulate coastal phytoplankton dynamics in the Bohai Bay. We demonstrate that this hybrid approach minimizes the need for expert elicitation, generates more reasonable structures for BN models, and increases the BN model＇s accuracy and reliability. These results suggest that the inclusion of SEM for testing and verifying the theoretical structure during the initial construction stage improves the effectiveness of BN models, especially for complex eco-environment systems. The results also demonstrate that in the Bohai Bay, while phytoplankton biomass has the greatest influence on phytoplankton dynamics, the impact of nutrients on phytoplankton dynamics is larger than the influence of the physical environment in summer. Furthermore, although the Redfield ratio indicates that phosphorus should be the primary nutrient limiting factor, our results show that silicate plays the most important role in regulating phytoplankton dynamics in the Bohai Bay.展开更多
The aim of this article is to develop a structural equation model to assess key factors of residents' support for hosting mega event based on previous literature.The model consisted of five latent constructs and e...The aim of this article is to develop a structural equation model to assess key factors of residents' support for hosting mega event based on previous literature.The model consisted of five latent constructs and eight path hypotheses.A survey was conducted in Shanghai before 2010 World Expo.It was found that the support for mega events is affected directly and/or indirectly by four determinants factors:perceived benefits,perceived costs,personal benefits and community attachment,and support relies heavily on perceived benefits rather than costs.This study contributes to the existing body of knowledge in an attempt to understand local residents' support for a mega event in different economic and cultural settings.展开更多
Under different conditions,gene regulatory networks(GRNs)of the same gene set could be similar but different.The differential analysis of GRNs under different conditions is important for understanding condition-specif...Under different conditions,gene regulatory networks(GRNs)of the same gene set could be similar but different.The differential analysis of GRNs under different conditions is important for understanding condition-specific gene regulatory relationships.In a naive approach,existing GRN inference algorithms can be used to separately estimate two GRNs under different conditions and identify the differences between them.However,in this way,the similarities between the pairwise GRNs are not taken into account.Several joint differential analysis algorithms have been proposed recently,which were proved to outperform the naive approach apparently.In this paper,we model the GRNs under different conditions with structural equation models(SEMs)to integrate gene expression data and genetic perturbations,and re-parameterize the pairwise SEMs to form an integrated model that incorporates the differential structure.Then,a Bayesian inference method is used to make joint differential analysis by solving the integrated model.We evaluated the performance of the proposed re-parametrization-based Bayesian differential analysis(ReBDA)algorithm by running simulations on synthetic data with different settings.The performance of the ReBDA algorithm was demonstrated better than another state-of-the-art joint differential analysis algorithm for SEMs ReDNet obviously.In the end,the ReBDA algorithm was applied to make differential analysis on a real human lung gene data set to illustrate its applicability and practicability.展开更多
Stakeholder analysis was conducted to define stakeholders and their role in clinical trials; a conceptual model and hypotheses regarding the relationship of each stakeholder were then constructed based on pharmaceutic...Stakeholder analysis was conducted to define stakeholders and their role in clinical trials; a conceptual model and hypotheses regarding the relationship of each stakeholder were then constructed based on pharmaceutical regulations in China and interviews with experts; Amos 17.0 was utilized to test the model and path analysis. We found that government and hospital are the most powerful stakeholders, while the public and sponsor have little impact on clinical trials. Further measures should be taken by sponsors to promote the development of clinical trials, and the public should be more involved in clinical research.展开更多
In order to know about the essence of service employees' innovation behavior, the service employees' innovation behavior scale based on their unique characteristics is designed. Data were collected from high-s...In order to know about the essence of service employees' innovation behavior, the service employees' innovation behavior scale based on their unique characteristics is designed. Data were collected from high-star hospitalities. Through the issuance and the collection of questionnaires, the scale is verified to have good reliability and validity by SPSS software analysis. Meanwhile,the structural equation model( SEM) is suited for testing structural dimensions of service employees' innovation behavior. The results showed that service employees' innovation behavior could be decomposed into a four-dimensional structure,namely innovation orientation, ideas generation, innovation implementation and innovation practice. In addition,there are significant differences in service employees' innovation behavior about subjects' gender,position,education background and years of working.展开更多
BACKGROUND Treatment efficacy for attention-deficit/hyperactivity disorder(ADHD)is reported to be poor,possibly due to heterogeneity of ADHD symptoms.Little is known about poor treatment efficacy owing to ADHD heterog...BACKGROUND Treatment efficacy for attention-deficit/hyperactivity disorder(ADHD)is reported to be poor,possibly due to heterogeneity of ADHD symptoms.Little is known about poor treatment efficacy owing to ADHD heterogeneity.AIM To use generalized structural equation modeling(GSEM)to show how the heterogeneous nature of hyperactivity/impulsivity(H/I)symptoms in ADHD,irritable oppositional defiant disorder(ODD),and the presentation of aggression in children interferes with treatment responses in ADHD.METHODS A total of 231 children and adolescents completed ADHD inattention and H/I tests.ODD scores from the Swanson,Nolan,and Pelham,version IV scale were obtained.The child behavior checklist(CBCL)and parent’s satisfaction questionnaire were completed.The relationships were analyzed by GSEM.RESULTS GSEM revealed that the chance of ADHD remission was lower in children with a combination of H/I symptoms of ADHD,ODD symptoms,and childhood aggressive behavior.ODD directly mediated ADHD symptom severity.The chance of reaching remission based on H/I symptoms of ADHD was reduced by 13.494%[=exp(2.602)]in children with comorbid ADHD and ODD[odds ratio(OR)=2.602,95%confidence interval(CI):1.832-3.373,P=0.000]after adjusting for the effects of other factors.Childhood aggression mediated ODD symptom severity.The chance of reaching remission based on ODD symptoms was lowered by 11.000%[=1-exp(-0.117)]in children with more severe baseline symptoms of aggression based on the CBCL score at study entry[OR=-0.117,95%CI:(-0.190)-(-0.044),P=0.002].CONCLUSION Mediation through ODD symptoms and aggression may influence treatment effects in ADHD after adjusting for the effects of baseline ADHD symptom severity.More attention could be directed to the early recognition of risks leading to ineffective ADHD treatment,e.g.,symptoms of ODD and the presentation of aggressive or delinquent behaviors and thought problems in children with ADHD.展开更多
Tracing the origins of business cost, to define the satisfaction assessment factors on the business cost in Shanghai was investigated in this paper. Arguing that these effects: a single low cost is not only the criter...Tracing the origins of business cost, to define the satisfaction assessment factors on the business cost in Shanghai was investigated in this paper. Arguing that these effects: a single low cost is not only the criterion determining satisfaction. Other important factors, such as enterprise internal cognitive attitude,stability of the external environment,the quality of perceptions of government services can affect satisfaction. Within structural equation modeling( SEM) approach, six sets of hypotheses are drawn up and tested with a sample of 338 enterprises using questionnaires. Additionally,the analyses of findings introduce the crucial importance of these features in the assessment of satisfaction with business cost in Shanghai. Finally, the results show that internal cognitive has a positive impact on satisfaction. Stability of the external environment has a significant relationship with the effectiveness of government services. Stability of the external environmeat and the effectiveness of government servises have a positive effect on satisfaction.展开更多
Factors affecting equipment maintenance quality usually include personnel,equipment and facilities,raw materials and spare parts, craft, environment and quality management. These six factors affecting maintenance qual...Factors affecting equipment maintenance quality usually include personnel,equipment and facilities,raw materials and spare parts, craft, environment and quality management. These six factors affecting maintenance quality are not all the same degree. In order to find out which factor can influence equipment maintenance quality greatly and achieve sophisticated management,characteristic quantities of six factors are presented. A structural equation modeling( SEM) is designed using the six factors as latent variables and their characteristic quantities as the observed variable.According to the basic data obtained from the questionnaire survey,calculate the standardized regression weight by parameter estimation of the SEM. Then the key factors affecting the quality of the equipment maintenance are determined with the help of the standardized regression weight.展开更多
基金Supported by the Korea Health Technology R&D Project through the Korea Health Industry Development Institute(KHIDI),funded by the Ministry of Health&Welfare,Republic of Korea(No.HR20C0026)the National Research Foundation of Korea(NRF)(No.RS-2023-00247504)the Patient-Centered Clinical Research Coordinating Center,funded by the Ministry of Health&Welfare,Republic of Korea(No.HC19C0276).
文摘AIM:To build a functional generalized estimating equation(GEE)model to detect glaucomatous visual field progression and compare the performance of the proposed method with that of commonly employed algorithms.METHODS:Totally 716 eyes of 716 patients with primary open angle glaucoma(POAG)with at least 5 reliable 24-2 test results and 2y of follow-up were selected.The functional GEE model was used to detect perimetric progression in the training dataset(501 eyes).In the testing dataset(215 eyes),progression was evaluated the functional GEE model,mean deviation(MD)and visual field index(VFI)rates of change,Advanced Glaucoma Intervention Study(AGIS)and Collaborative Initial Glaucoma Treatment Study(CIGTS)scores,and pointwise linear regression(PLR).RESULTS:The proposed method showed the highest proportion of eyes detected as progression(54.4%),followed by the VFI rate(34.4%),PLR(23.3%),and MD rate(21.4%).The CIGTS and AGIS scores had a lower proportion of eyes detected as progression(7.9%and 5.1%,respectively).The time to detection of progression was significantly shorter for the proposed method than that of other algorithms(adjusted P≤0.019).The VFI rate displayed moderate pairwise agreement with the proposed method(k=0.47).CONCLUSION:The functional GEE model shows the highest proportion of eyes detected as perimetric progression and the shortest time to detect perimetric progression in patients with POAG.
基金Under the auspices of the National Natural Science Foundation of China(No.42371222,41971167)Fundamental Scientific Research Funds of Central China Normal University(No.CCNU24ZZ120)。
文摘Owing to intensified globalization and informatization,the structures of the urban scale hierarchy and urban networks between cities have become increasingly intertwined,resulting in different spatial effects.Therefore,this paper analyzes the spatial interaction between urban scale hierarchy and urban networks in China from 2019 to 2023,drawing on Baidu migration data and employing a spatial simultaneous equation model.The results reveal a significant positive spatial correlation between cities with higher hierarchy and those with greater network centrality.Within a static framework,we identify a positive interaction between urban scale hierarchy and urban network centrality,while their spatial cross-effects manifest as negative neighborhood interactions based on geographical distance and positive cross-scale interactions shaped by network connections.Within a dynamic framework,changes in urban scale hierarchy and urban networks are mutually reinforcing,thereby widening disparities within the urban hierarchy.Furthermore,an increase in a city’s network centrality had a dampening effect on the population growth of neighboring cities and network-connected cities.This study enhances understanding of the spatial organisation of urban systems and offers insights for coordinated regional development.
基金supported by the 2021 Shandong Province Higher Education Institutions“Youth Innovation Talent Introduction and Cultivation Plan”(Public Health Safety Risk Assessment and Response Innovation Team)National Traditional Chinese Medicine Comprehensive Reform Demonstration Zone Science and Technology Co construction Project(No.GZYKJSSD-2024-106)Research Project of Shandong Educational Supervision Society(No.SDJYDDXH2023-2159).
文摘Dentistry is a profession with a high prevalence of work-related musculoskeletal disorders(WMSDs),with symptoms often appearing very early in one’s career[1].WMSDs are conditions affecting the muscles,bones,and nervous system due to occupational factors.In 2002,the International Labor Organization included musculoskeletal diseases in the International List of Occupational Diseases.China’s recently updated Classification and Catalog of Occupational Diseases has introduced two new categories of occupational illnesses,including occupational musculoskeletal disorders.WMSDs significantly impact the health and work of dentists,reducing their quality of life and causing economic losses.These disorders are multifactorial in nature,influenced by personal,psychosocial,biomechanical,and environmental factors.Dentists frequently maintain static or awkward postures during procedures,which leads to musculoskeletal strain and discomfort;additionally,long working hours contribute to psychological stress,further increasing the risk of WMSDs[2].
基金Research Council of Lithuania(LMTLT),agreement No.S-PD-24-120Research Council of Lithuania(LMTLT),agreement No.S-PD-24-120funded by the Research Council of Lithuania.
文摘Fractional differential equations(FDEs)provide a powerful tool for modeling systems with memory and non-local effects,but understanding their underlying structure remains a significant challenge.While numerous numerical and semi-analytical methods exist to find solutions,new approaches are needed to analyze the intrinsic properties of the FDEs themselves.This paper introduces a novel computational framework for the structural analysis of FDEs involving iterated Caputo derivatives.The methodology is based on a transformation that recasts the original FDE into an equivalent higher-order form,represented as the sum of a closed-form,integer-order component G(y)and a residual fractional power seriesΨ(x).This transformed FDE is subsequently reduced to a first-order ordinary differential equation(ODE).The primary novelty of the proposed methodology lies in treating the structure of the integer-order component G(y)not as fixed,but as a parameterizable polynomial whose coefficients can be determined via global optimization.Using particle swarm optimization,the framework identifies an optimal ODE architecture by minimizing a dual objective that balances solution accuracy against a high-fidelity reference and the magnitude of the truncated residual series.The effectiveness of the approach is demonstrated on both a linear FDE and a nonlinear fractional Riccati equation.Results demonstrate that the framework successfully identifies an optimal,low-degree polynomial ODE architecture that is not necessarily identical to the forcing function of the original FDE.This work provides a new tool for analyzing the underlying structure of FDEs and gaining deeper insights into the interplay between local and non-local dynamics in fractional systems.
基金Under the auspices of Forestry Industry Research Special Funds for Public Welfare Projects(No.201004008)National Natural Science Foundation of China(No.71003007)Research Program of Food and Agriculture Organization(No.CHN/2011/077/LOA)
文摘A households′production behavior directly influences the quality of the environment and determines the successful development of nature reserves.Meanwhile,the households′production behaviors are complicated by interrelated factors,such as protection attitudes,resource endowment,and family wealth.This research evaluated households near the Crested Ibis National Nature Reserve in Shaanxi Province,acquiring data from 436 households around Yang County and Ningshan County in the south slope of Qinling Mountains,China.Based on the collected data,we developed a structural equation model to evaluate the coupling relationships among households′ protection attitudes,production behaviors,resource endowment,and family wealth.The results showed that:1) households with great resource endowment had more negative attitudes,probably due to their greater protection costs;2) the households with higher education levels had worse protection attitudes;3) the households with more family wealth were likely to use fewer fertilizers,pesticides,and firewood;4) the households with more resource endowment showed less production and management behaviors;5) the enhancement of households' attitudes improved production behaviors to protection the environment,but the effects were not statistically significant.Our results provide a basis for the government's protection policy making,exploring the effective management measures that are beneficial for both nature reserve management and community development.
文摘Work injuries in mines are complex and generally characterized by several factors starting from personal to technical and technical to social characteristics.In this paper,investigation was made through the application of structural equation modeling to study the nature of relationships between the influencing/associating personal factors and work injury and their sequential relationships leading towards work injury occurrences in underground coal mines.Six variables namely,rebelliousness,negative affectivity,job boredom,job dissatisfaction and work injury were considered in this study.Instruments were developed to quantify them through a questionnaire survey.Underground mine workers were randomly selected for the survey.Responses from 300 participants were used for the analysis.The structural model of LISREL was used to estimate the interrelationships amongst the variables.The case study results show that negative affectivity and job boredom induce more job dissatisfaction to the workers whereas risk taking attitude of the individual is positively influenced by job dissatisfaction as well as by rebelliousness characteristics of the individual.Finally,risk taking and job dissatisfaction are having positive significant direct relationship with work injury.The findings of this study clearly reveal that rebelliousness,negative affectivity and job boredom are the three key personal factors influencing work related injuries in mines that need to be addressed properly through effective safety programs.
文摘Purpose:This paper aims to examine how the adoption decision of the internet banking in North Cyprus would be affected based on the following dimensions;the technology features,the personal characteristics,the social environment and the expected risk.Design/methodology/approach:A self-administered survey was conducted with 291 participants responded to it.The partial least square approach of the structural equation modeling(PLS-SEM)is employed to investigate the direct effects of the proposed factors on the adoption decision.Additionally,the mediation test is used to examine indirect effects.Findings:Results showed that even though the participants appreciated the benefits of the online banking as the perceived usefulness factor exerts the greatest direct effect,they would rather use clear and easy-to-use websites,adding to that their assessments of the usefulness of these services are significantly influenced by the surrounding people’s views and prior experience.This is demonstrated by the total effects of the perceived ease of use and the subjective norm factors,which are greater than the direct effect of the perceived usefulness factor since both of these factors have significant direct and indirect effects mediated by the perceived usefulness factor.The negative impact of the perceived risk factor is weak compared to the previous factors.While the personal innovativeness factor showed the weakest effect among the proposed factors.
基金This study was supported by the Fundamental Research Funds for the Central Universities(No.5003516009).
文摘This study aimed to construct a quality management model for phase I clinical drug trials.A cross-sectional survey was conducted and data were collected from 604 respondents at 69 institutions in China engaged in phase I clinical drug trials.Exploratory and confirmatory factor analyses were used to develop the survey tool.Structural equation modeling was used to construct a quality management model for phase I clinical drug trials.The results showed that the final survey tool had good reliability and validity(Cronbach’sα=0.938,root mean square error of approximation=0.074,comparative fit index=0.962,and Tucker—Lewis index=0.955).The model included five dimensions:government regulation,industry management,medical institution management,research team management,and contract research organization(CRO)management.In total,22 measurement items were obtained.The structural equation model indicated government regulation,industry management,medical institution management,and CRO management significantly affected the quality of phase I clinical drug trials(β=0.195,β=0.331,β=0.279,andβ=−0.267,respectively;P<0.05).Research team management had no effect on the quality of trials(β=0.041,P=0.610).In conclusion,the model is valuable for identifying factors influencing phase I clinical drug trials and guiding quality management practices.
基金Funded by the R & D Project of the Ministry of Construction of China.
文摘This paper describes a structural equation modeling （SEM） analysis of factors influencing architects＇ trust in project design teams. We undertook a survey of architects, during which we distributed 193 questionnaires in 29 A-level architectural design institutes selected radomly from the altogether 59 ones in Shenzhen, P. R. China, and received 130 valid questionnaires. We used Amos 6.0 for SEM to identify significant personal construct based factors affecting interpersonal trust. The results show that only social interaction between architects significantly affects their interpersonal trust. The explained variance of trus~ is not very high in the model. Therefore, future research should add more factors into the current model. The practical implication is that team managers should promote the social interactions between team members such that the interpersonal trust level between team members can be improved.
文摘Structural Equation Modeling （SEM） used widely in sociology, economics and psychology is adopted. Based on data obtained from marketing research, and using statistical analysis software SPSSll. 0 and LISRELS. 7, Theory of Five Dimensions of service quality is proved to be suitable in sportswear retailing in China. It analyzes the relationship among five dimensions and puts them in order of importance as to service quality in sportswear retailing. Advices are given for sportswear retail companies to improve their .Service quality and enhance customer loyalty.
文摘The structural equation model (SEM) concept is generally influenced by the presence of outliers and controlling variables. To a very large extent, this could have consequential effects on the parameters and the model fitness. Though previous researches have studied outliers and controlling observations from various perspectives including the use of box plots, normal probability plots, among others, the use of uniform horizontal QQ plot is yet to be explored. This study is, therefore, aimed at applying uniform QQ plots to identifying outliers and possible controlling observations in SEM. The results showed that all the three methods of estimators manifest the ability to identify outliers and possible controlling observations in SEM. It was noted that the Anderson-Rubin estimator of QQ plot showed a more efficient or visual display of spotting outliers and possible controlling observations as compared to the other methods of estimators. Therefore, this paper provides an efficient way identifying outliers as it fragments the data set.
基金Supported by the National Natural Science Foundation of China(42302141).
文摘Taking the second member of the Xujiahe Formation of the Upper Triassic in the Xinchang structural belt as an example,based on data such as logging,production,seismic interpretation and test,a systematic analysis was conducted on the structural characteristics and evolution,reservoir diagenesis and densification processes,and types and stages of faults/fractures,and revealing the multi-stage and multi-factor dynamic coupled enrichment mechanisms of tight gas reservoirs.(1)In the early Yanshan period,the paleo-structural traps were formed with low-medium maturity hydrocarbons accumulating in structural highs driven by buoyancy since reservoirs were not fully densified in this stage,demonstrating paleo-structure control on traps and early hydrocarbon accumulation.(2)In the middle-late Yanshan period,the source rocks became mature to generate and expel a large quantity of hydrocarbons.Grain size and type of sandstone controlled the time of reservoir densification,which restricted the scale of hydrocarbon charging,allowing for only a small-scale migration through sand bodies near the fault/fracture or less-densified matrix reservoirs.(3)During the Himalayan period,the source rocks reached overmaturity,and the residual oil cracking gas was efficiently transported along the late-stage faults/fractures.Wells with high production capacity were mainly located in Type I and II fault/fracture zones comprising the late-stage north-south trending fourth-order faults and the late-stage fractures.The productivity of the wells was controlled by the transformation of the late-stage faults/fractures.(4)The Xinchang structural belt underwent three stages of tectonic evolution,two stages of reservoir formation,and three stages of fault/fractures development.Hydrocarbons mainly accumulated in the paleo-structure highs.After reservoir densification and late fault/fracture adjustment,a complex gas-water distribution pattern was formed.Thus,it is summarized as the model of“near-source and low-abundance hydrocarbon charging in the early stage,and differential enrichment of natural gas under the joint control of fault-fold-fracture complex,high-quality reservoirs and structural highs in the late stage”.Faults/fractures with well-coupled fault-fold-fracture-pore are favorable exploration targets with high exploration effectiveness.
基金supported by the Natural Science Foundation of Tianjin(Grant No.16JCYBJC23000)the Open Foundation of the Key Laboratory for Ecological Environment in Coastal Areas of the State Oceanic Administration(Grant No.201604)Science and Technology Foundation for Young Scholars from Tianjin Fisheries Bureau(Grant No.J2014-05)
文摘Bayesian networks （BN） have many advantages over other methods in ecological modeling, and have become an increasingly popular modeling tool. However, BN are flawed in regard to building models based on inadequate existing knowledge. To overcome this limitation, we propose a new method that links BN with structural equation modeling （SEM）. In this method, SEM is used to improve the model structure for BN. This method was used to simulate coastal phytoplankton dynamics in the Bohai Bay. We demonstrate that this hybrid approach minimizes the need for expert elicitation, generates more reasonable structures for BN models, and increases the BN model＇s accuracy and reliability. These results suggest that the inclusion of SEM for testing and verifying the theoretical structure during the initial construction stage improves the effectiveness of BN models, especially for complex eco-environment systems. The results also demonstrate that in the Bohai Bay, while phytoplankton biomass has the greatest influence on phytoplankton dynamics, the impact of nutrients on phytoplankton dynamics is larger than the influence of the physical environment in summer. Furthermore, although the Redfield ratio indicates that phosphorus should be the primary nutrient limiting factor, our results show that silicate plays the most important role in regulating phytoplankton dynamics in the Bohai Bay.
基金supported by Shanghai Municipal Education Commission (Grant no.egd08025)
文摘The aim of this article is to develop a structural equation model to assess key factors of residents' support for hosting mega event based on previous literature.The model consisted of five latent constructs and eight path hypotheses.A survey was conducted in Shanghai before 2010 World Expo.It was found that the support for mega events is affected directly and/or indirectly by four determinants factors:perceived benefits,perceived costs,personal benefits and community attachment,and support relies heavily on perceived benefits rather than costs.This study contributes to the existing body of knowledge in an attempt to understand local residents' support for a mega event in different economic and cultural settings.
基金supported by grants from National Natural Science Foundation of China(Nos.61502198,61572226,61472161,61876069)。
文摘Under different conditions,gene regulatory networks(GRNs)of the same gene set could be similar but different.The differential analysis of GRNs under different conditions is important for understanding condition-specific gene regulatory relationships.In a naive approach,existing GRN inference algorithms can be used to separately estimate two GRNs under different conditions and identify the differences between them.However,in this way,the similarities between the pairwise GRNs are not taken into account.Several joint differential analysis algorithms have been proposed recently,which were proved to outperform the naive approach apparently.In this paper,we model the GRNs under different conditions with structural equation models(SEMs)to integrate gene expression data and genetic perturbations,and re-parameterize the pairwise SEMs to form an integrated model that incorporates the differential structure.Then,a Bayesian inference method is used to make joint differential analysis by solving the integrated model.We evaluated the performance of the proposed re-parametrization-based Bayesian differential analysis(ReBDA)algorithm by running simulations on synthetic data with different settings.The performance of the ReBDA algorithm was demonstrated better than another state-of-the-art joint differential analysis algorithm for SEMs ReDNet obviously.In the end,the ReBDA algorithm was applied to make differential analysis on a real human lung gene data set to illustrate its applicability and practicability.
文摘Stakeholder analysis was conducted to define stakeholders and their role in clinical trials; a conceptual model and hypotheses regarding the relationship of each stakeholder were then constructed based on pharmaceutical regulations in China and interviews with experts; Amos 17.0 was utilized to test the model and path analysis. We found that government and hospital are the most powerful stakeholders, while the public and sponsor have little impact on clinical trials. Further measures should be taken by sponsors to promote the development of clinical trials, and the public should be more involved in clinical research.
基金Shanghai University of Engineering Science's Research Cultivation Fund Project,China(No.A25001201194)National Natural Science Foundation,China(No.71301100)+1 种基金the Fundamental Research Funds for the Central Universities,China(No.JB-SK1204)China Postdoctoral Science Foundation(No.2014M561655)
文摘In order to know about the essence of service employees' innovation behavior, the service employees' innovation behavior scale based on their unique characteristics is designed. Data were collected from high-star hospitalities. Through the issuance and the collection of questionnaires, the scale is verified to have good reliability and validity by SPSS software analysis. Meanwhile,the structural equation model( SEM) is suited for testing structural dimensions of service employees' innovation behavior. The results showed that service employees' innovation behavior could be decomposed into a four-dimensional structure,namely innovation orientation, ideas generation, innovation implementation and innovation practice. In addition,there are significant differences in service employees' innovation behavior about subjects' gender,position,education background and years of working.
文摘BACKGROUND Treatment efficacy for attention-deficit/hyperactivity disorder(ADHD)is reported to be poor,possibly due to heterogeneity of ADHD symptoms.Little is known about poor treatment efficacy owing to ADHD heterogeneity.AIM To use generalized structural equation modeling(GSEM)to show how the heterogeneous nature of hyperactivity/impulsivity(H/I)symptoms in ADHD,irritable oppositional defiant disorder(ODD),and the presentation of aggression in children interferes with treatment responses in ADHD.METHODS A total of 231 children and adolescents completed ADHD inattention and H/I tests.ODD scores from the Swanson,Nolan,and Pelham,version IV scale were obtained.The child behavior checklist(CBCL)and parent’s satisfaction questionnaire were completed.The relationships were analyzed by GSEM.RESULTS GSEM revealed that the chance of ADHD remission was lower in children with a combination of H/I symptoms of ADHD,ODD symptoms,and childhood aggressive behavior.ODD directly mediated ADHD symptom severity.The chance of reaching remission based on H/I symptoms of ADHD was reduced by 13.494%[=exp(2.602)]in children with comorbid ADHD and ODD[odds ratio(OR)=2.602,95%confidence interval(CI):1.832-3.373,P=0.000]after adjusting for the effects of other factors.Childhood aggression mediated ODD symptom severity.The chance of reaching remission based on ODD symptoms was lowered by 11.000%[=1-exp(-0.117)]in children with more severe baseline symptoms of aggression based on the CBCL score at study entry[OR=-0.117,95%CI:(-0.190)-(-0.044),P=0.002].CONCLUSION Mediation through ODD symptoms and aggression may influence treatment effects in ADHD after adjusting for the effects of baseline ADHD symptom severity.More attention could be directed to the early recognition of risks leading to ineffective ADHD treatment,e.g.,symptoms of ODD and the presentation of aggressive or delinquent behaviors and thought problems in children with ADHD.
基金National Social Science Foundation of China(No.10BJL044)Doctoral Innovation Project of Donghua University:the Central Universities Science Fundamental Research in China(No.CUSF-DH-D-2015064)
文摘Tracing the origins of business cost, to define the satisfaction assessment factors on the business cost in Shanghai was investigated in this paper. Arguing that these effects: a single low cost is not only the criterion determining satisfaction. Other important factors, such as enterprise internal cognitive attitude,stability of the external environment,the quality of perceptions of government services can affect satisfaction. Within structural equation modeling( SEM) approach, six sets of hypotheses are drawn up and tested with a sample of 338 enterprises using questionnaires. Additionally,the analyses of findings introduce the crucial importance of these features in the assessment of satisfaction with business cost in Shanghai. Finally, the results show that internal cognitive has a positive impact on satisfaction. Stability of the external environment has a significant relationship with the effectiveness of government services. Stability of the external environmeat and the effectiveness of government servises have a positive effect on satisfaction.
文摘Factors affecting equipment maintenance quality usually include personnel,equipment and facilities,raw materials and spare parts, craft, environment and quality management. These six factors affecting maintenance quality are not all the same degree. In order to find out which factor can influence equipment maintenance quality greatly and achieve sophisticated management,characteristic quantities of six factors are presented. A structural equation modeling( SEM) is designed using the six factors as latent variables and their characteristic quantities as the observed variable.According to the basic data obtained from the questionnaire survey,calculate the standardized regression weight by parameter estimation of the SEM. Then the key factors affecting the quality of the equipment maintenance are determined with the help of the standardized regression weight.
