Objective: to investigate the clinical significance, statistical intervention effect, and evaluate the quality of life of patients with stroke sequelae treated with Pentagon in rehabilitation care. Methods: in this ho...Objective: to investigate the clinical significance, statistical intervention effect, and evaluate the quality of life of patients with stroke sequelae treated with Pentagon in rehabilitation care. Methods: in this hospital, patients with stroke sequelae hospitalized from January 2021 to December 2021 were divided into two groups, including 40 cases as the control group and 40 cases as the control group, which underwent rehabilitation using pentatone therapy. Results: compared with the control group, the scores of SAS and SDS scales were significantly lower;Scores on the SF-36 were higher than in the control group;The NIHSS score of the observation group was lower than that of the control group, the Fugl Meyer score was higher than that of the control group, and the Barthel index was higher than that of the control group;Lower PSQI score than control group, P < 0.05;In terms of satisfaction, the study group had a higher rating of the nurses satisfaction with their work, P < 0.05;Conclusion: in the clinical care of patients with post-stroke disabilities, the five sound therapy combined with rehabilitation care can effectively improve their neurological and limb functions, alleviate their negative emotions and improve their quality of survival.展开更多
Post-stroke swallowing disorder is an important factor affecting the rehabilitation of stroke patients.There are many clinical treatment methods such as physical therapy and acupuncture.From the literature in recent y...Post-stroke swallowing disorder is an important factor affecting the rehabilitation of stroke patients.There are many clinical treatment methods such as physical therapy and acupuncture.From the literature in recent years,acupuncture points,acupuncture manipulation,acupuncture amount,combined with other treatment methods,and acupoint selection based on syndrome differentiation are reviewed.It is clinically proved that acupuncture is effective in treating stroke accompanied by swallowing disorder.Different acupuncture methods need to select different acupoints,and different doctors have different acupuncture techniques,which reflects the syndrome differentiation and treatment of traditional Chinese medicine.Summarizing the literature is convenient in guiding patients to select acupoints more precisely and easily in treatment.In the future,more patient samples,multiple clinical centers and more standardized controlled clinical trials will be adopted to find out the theoretical basis of traditional Chinese medicine for acupuncture treatment of post-stroke swallowing disorder and the specific effective acupoints in acupuncture treatment,so as to facilitate learning,communication,popularization and application in primary clinical practice.展开更多
The research progress of brain-derived neurotrophic factor (BDNF) in the treatment of sequelae of stroke is an important topic. Stroke is among the diseases with the highest mortality and disability rates among the el...The research progress of brain-derived neurotrophic factor (BDNF) in the treatment of sequelae of stroke is an important topic. Stroke is among the diseases with the highest mortality and disability rates among the elderly in China. BDNF plays an important role in the development and functional maintenance of the nervous system. In recent years, the application value of BDNF in rehabilitation therapy has gradually received attention. This study has adopted a systematic literature review method, searched Chinese and English databases, screened relevant studies, and conducted data extraction and quality evaluation. This review systematically introduced the research progress of BDNF in the correlation with post-stroke sequelae, with special attention to its application in post-stroke depression, motor dysfunction, and cognitive dysfunction. The results showed that a decrease in BDNF levels is closely related to the exacerbation of depressive symptoms, limited recovery of motor dysfunction, and the occurrence of cognitive dysfunction. BDNF, as a key neurobiological factor, has shown significant potential in the rehabilitation treatment of stroke. By exploring the potential of BDNF as a therapeutic target to prevent and treat sequelae of ischemic stroke, the current research bottlenecks, and the development trends of future treatment strategies.展开更多
Objective To explore the effect of meridian sinew row needling combined with dermal needling on spasticity of post-stroke patients with upper limb hemiparalysis. Methods Four hundred and eighty-eight cases of post-str...Objective To explore the effect of meridian sinew row needling combined with dermal needling on spasticity of post-stroke patients with upper limb hemiparalysis. Methods Four hundred and eighty-eight cases of post-stroke patients with upper limb spasticity were randomly divided into two groups at the ratio of 1： 1, the group of meridian sinew row needling combined with dermal needling （group A, 244 cases） and western medication group （group B, 244 cases）. Coupled with rehabilitation, the patients in the group A were given meridian sinew row needling combined with dermal needling where five shu points were specifically selected, and three yang meridians of the hand were treated with acupuncture with muscle region, and three yin meridians of the hand were treated with dermal needles; the patients in the group B was treated with conventional western medication with piracetam injection and cerebroprotein hydrolysate included. Clinical efficacy was evaluated among patients in the two groups after three weeks of continuous treatment, and upper limb spasticity and motor functions were observed through modified Asworth Scale and FugI-Meyer Assessment Scale （FMA） before and after treatment. Results For Asworth Scale, group A was significantly superior to group B （3.04 ± 1.29 vs 3.88 ± 1.54, P〈0.05）; for FMA scale, group A was also significantly superior to group B （48.67± 15.64 vs 42.96±14.72, P〈0.05）; mitigations of motor status of upper limb joints in group A, such as remission of shoulder adduction （90.5%）, pronation of forearm （70.7%）, elbow joint flexion （73.1%）, wrist joint flexion （80.9%） and finger flexion （88.1%）, were superior to those of group B （70.0%, 60.0%, 61.9%, 57.4%, 63.2%, all P〈0.05）. Conclusion Good clinical efficacy of the treatment with combined with dermal needling on spasticity of post-stroke patients with upper limb hemiparalysis is achieved.展开更多
BACKGROUND: Transplanted mononuclear cell (MNC) of umbilical blood can survive in central nervous system (CNS) of host through blood brain barrier, differentiate into nerve cells, migrate to damaged site and integrate...BACKGROUND: Transplanted mononuclear cell (MNC) of umbilical blood can survive in central nervous system (CNS) of host through blood brain barrier, differentiate into nerve cells, migrate to damaged site and integrate morphological structure and function with nerve cells of host so as to improve deficiencies of sensatory function, motor function and cognitive function and influence on stroke sequela. OBJECTIVE: To observe the vein transplantation of human umbilical cord blood stem cells (HUCBSC) for improving neurological function, limb function and activity of daily living of patients with stroke and evaluate the reliability. DESIGN: Self-controlled study. SETTING: Department of Neurosurgery, the Second People's Hospital of Zhengzhou City; Red-crossed Blood Center of Henan Province; Department of Neurosurgery, the Fist Affiliated Hospital of Zhengzhou University. PARTICIPANTS: A total of 10 patients with stroke sequela were selected from Department of Cerebral Surgery, the Second People's Hospital of Zhengzhou City from April to December 2005. There were 9 males and 1 female aged from 35 to 75 years with the mean age of 56 years. All of them were diagnosed with CT and MRI examination and coincidence with diagnostic criteria of stroke established by the Fourth National Academic Meeting for Cerebrovascular Disease. All patients provided informed consent. METHODS: 80-140 mL umbilical blood of term birth of newborn was selected hermetically and maintained in sterile plastic bag. And then, the blood was centrifugated at the speed of 1 500 r/min for 30 minutes at 22 ℃ in order to separate MNC, i.e., HUCBSC. In addition, after final diagnosis during hospitalization, stroke patients were perfused with HUCBSC through superficial vein of back of the hand. Each patient was averagely perfused with 6 portions of HUCBSC (cellular numbers ≥ 1×108/portion) and the interval between each portion was 1-7 days with the mean interval of 4 days. MAIN OUTCOME MEASURES: ① Neurological function of stroke patients was evaluated with neurological function deficiency (NFD) before treatment and at 3 months after treatment. The scale includes consciousness, level fix function, facial paralysis, language, muscle force of upper limbs, muscle force of lower limb and step function. The total scores ranged from 0 to 45; meanwhile, the lower the scores were, the better the neurological function was. ② Motor function of injured limbs was evaluated with Fugl-Meyer Assessment (FMA), including motor function of upper limbs, motor function of lower limbs, balance ability, sensory function and motion of joint. The total scores ranged from 0 to 226; meanwhile, the higher the scores were, the better the motor function of limbs was. ③ Activities of daily living (ADL) was evaluated with Barthel Index (BI), including having meals, taking a bath, dressing oneself, putting on clothes, walking in balance and stair activity. The total scores ranged from 0 to 100; meanwhile, the higher the scores were, the stronger the ADL was. RESULTS: A total of 10 patients were involved in the final analysis. After treatment, NFD of stroke patients was (10.9±5.09) points, which was lower than that before treatment [(25.4±6.09) points, t =8.213, P < 0.01]. In addition, after treatment, FMA and BI of stroke patients were (80.9±25.00) points and (81.1±15.93) points, respectively, which were higher than those before treatment [(31.9±21.85) points, (36.2±19.41) points, t =13.024, 13.670, P < 0.01]. Immuno-suppressive drugs were not used during the whole therapeutic procedure; moreover, immunological rejection and allergic reaction were not observed during the same period. CONCLUSION: Transplanting HUCBSC through superficial vein of back of the hand is regarded as a simple and safe method for the treatment of stroke sequela.展开更多
Objective To investigate clinical effects of acupuncture method for dredging collaterals and resolving phlegm on stroke in Congo. Methods The patients in Congo China-Congo Friendship Hospital were randomly divided int...Objective To investigate clinical effects of acupuncture method for dredging collaterals and resolving phlegm on stroke in Congo. Methods The patients in Congo China-Congo Friendship Hospital were randomly divided into an acupuncture group and a medicine group, 30 cases in each group. For the acupuncture group, Moiluoning injection was administrated by intravenous drip and acupuncture was given at Sishencong （四神聪 EX-HN 1）, Zhangwan （中脘 CV 12）, Fenglong （丰隆 ST 40） and Neiguan （内关 PC 6）, etc., once daily for 10 consecutive days as a course of treatment. For the medicine group, 20 mL Moiluoning or 500 mL low molecular Dextran injection was administrated by intravenous drip, once each day for 10 consecutive days as a course of treatment. After 3 therapeutic courses, clinical therapeutic effects were assessed. Results After treatment, the scores for nervous function were significantly decreased in the two groups （both P〈0.05）, with a significant difference between the two groups （P〈0.05）, the acupuncture group being superior to the medicine group; the effective rate （93.3%, 28/30） of the acupuncture group was significantly higher than that （80.0%, 24/30） of the medicine group （P〈0.05）. Conclusion Acupuncture with the method for dredging collaterals and resolving phlegm has a significant clinical effect on stroke.展开更多
Objective: to study the effect and evaluation of Buyang Huanwu Decoction on sequela of cerebral apoplexy. Methods: According to the inclusion and exclusion criteria, 80 patients with sequela of cerebral apoplexy were ...Objective: to study the effect and evaluation of Buyang Huanwu Decoction on sequela of cerebral apoplexy. Methods: According to the inclusion and exclusion criteria, 80 patients with sequela of cerebral apoplexy were selected from November 2018 to November 2020, grouping was completed according to the order of admission. The first 40 patients in the control group received conventional treatment, and the last 40 patients in the experimental group were combined with Buyang Huanwu Decoction for treatment, and the therapeutic effects were compared. Results: after the implementation of different treatment programs, the limb function of the experimental group was well recovered, and the daily living ability, cognitive function and neurologic impairment of the patients were significantly improved compared with the control group, with statistical significance (P < 0.05). Conclusion: routine acupuncture and Buyang Huanwu Decoction can effectively alleviate sequela, and the prognosis of patients with sequela is good. The indicators including daily recovery of limb function, cognitive function and neurological function are significantly improved, and the quality of life is significantly improved. It has the value of promotion and use.展开更多
Objective： To describe the effect of acupuncture with a new acupoint prescription in treating dysphagia from a chronic stroke patient by fiberoptic endoscopic evaluation of swallowing （FEES）. Methods： A case of ch...Objective： To describe the effect of acupuncture with a new acupoint prescription in treating dysphagia from a chronic stroke patient by fiberoptic endoscopic evaluation of swallowing （FEES）. Methods： A case of chronic dysphagic stroke patient was treated by acupuncture with 5 established acupoints, and assessed by FEES before and after 4-week treatments. Results： There is improvement in swallowing and speech function after acupuncture treatment. Conclusion： There is evidence showing that new acupuncture points maybe beneficial for dysphagic stroke patients.展开更多
文摘Objective: to investigate the clinical significance, statistical intervention effect, and evaluate the quality of life of patients with stroke sequelae treated with Pentagon in rehabilitation care. Methods: in this hospital, patients with stroke sequelae hospitalized from January 2021 to December 2021 were divided into two groups, including 40 cases as the control group and 40 cases as the control group, which underwent rehabilitation using pentatone therapy. Results: compared with the control group, the scores of SAS and SDS scales were significantly lower;Scores on the SF-36 were higher than in the control group;The NIHSS score of the observation group was lower than that of the control group, the Fugl Meyer score was higher than that of the control group, and the Barthel index was higher than that of the control group;Lower PSQI score than control group, P < 0.05;In terms of satisfaction, the study group had a higher rating of the nurses satisfaction with their work, P < 0.05;Conclusion: in the clinical care of patients with post-stroke disabilities, the five sound therapy combined with rehabilitation care can effectively improve their neurological and limb functions, alleviate their negative emotions and improve their quality of survival.
基金Supported by Graduate Innovation Program of Bengbu Medical University(BYYCX1981).
文摘Post-stroke swallowing disorder is an important factor affecting the rehabilitation of stroke patients.There are many clinical treatment methods such as physical therapy and acupuncture.From the literature in recent years,acupuncture points,acupuncture manipulation,acupuncture amount,combined with other treatment methods,and acupoint selection based on syndrome differentiation are reviewed.It is clinically proved that acupuncture is effective in treating stroke accompanied by swallowing disorder.Different acupuncture methods need to select different acupoints,and different doctors have different acupuncture techniques,which reflects the syndrome differentiation and treatment of traditional Chinese medicine.Summarizing the literature is convenient in guiding patients to select acupoints more precisely and easily in treatment.In the future,more patient samples,multiple clinical centers and more standardized controlled clinical trials will be adopted to find out the theoretical basis of traditional Chinese medicine for acupuncture treatment of post-stroke swallowing disorder and the specific effective acupoints in acupuncture treatment,so as to facilitate learning,communication,popularization and application in primary clinical practice.
文摘The research progress of brain-derived neurotrophic factor (BDNF) in the treatment of sequelae of stroke is an important topic. Stroke is among the diseases with the highest mortality and disability rates among the elderly in China. BDNF plays an important role in the development and functional maintenance of the nervous system. In recent years, the application value of BDNF in rehabilitation therapy has gradually received attention. This study has adopted a systematic literature review method, searched Chinese and English databases, screened relevant studies, and conducted data extraction and quality evaluation. This review systematically introduced the research progress of BDNF in the correlation with post-stroke sequelae, with special attention to its application in post-stroke depression, motor dysfunction, and cognitive dysfunction. The results showed that a decrease in BDNF levels is closely related to the exacerbation of depressive symptoms, limited recovery of motor dysfunction, and the occurrence of cognitive dysfunction. BDNF, as a key neurobiological factor, has shown significant potential in the rehabilitation treatment of stroke. By exploring the potential of BDNF as a therapeutic target to prevent and treat sequelae of ischemic stroke, the current research bottlenecks, and the development trends of future treatment strategies.
基金Supported by Hebei Administration of Traditional Chinese Medicine(2009180)
文摘Objective To explore the effect of meridian sinew row needling combined with dermal needling on spasticity of post-stroke patients with upper limb hemiparalysis. Methods Four hundred and eighty-eight cases of post-stroke patients with upper limb spasticity were randomly divided into two groups at the ratio of 1： 1, the group of meridian sinew row needling combined with dermal needling （group A, 244 cases） and western medication group （group B, 244 cases）. Coupled with rehabilitation, the patients in the group A were given meridian sinew row needling combined with dermal needling where five shu points were specifically selected, and three yang meridians of the hand were treated with acupuncture with muscle region, and three yin meridians of the hand were treated with dermal needles; the patients in the group B was treated with conventional western medication with piracetam injection and cerebroprotein hydrolysate included. Clinical efficacy was evaluated among patients in the two groups after three weeks of continuous treatment, and upper limb spasticity and motor functions were observed through modified Asworth Scale and FugI-Meyer Assessment Scale （FMA） before and after treatment. Results For Asworth Scale, group A was significantly superior to group B （3.04 ± 1.29 vs 3.88 ± 1.54, P〈0.05）; for FMA scale, group A was also significantly superior to group B （48.67± 15.64 vs 42.96±14.72, P〈0.05）; mitigations of motor status of upper limb joints in group A, such as remission of shoulder adduction （90.5%）, pronation of forearm （70.7%）, elbow joint flexion （73.1%）, wrist joint flexion （80.9%） and finger flexion （88.1%）, were superior to those of group B （70.0%, 60.0%, 61.9%, 57.4%, 63.2%, all P〈0.05）. Conclusion Good clinical efficacy of the treatment with combined with dermal needling on spasticity of post-stroke patients with upper limb hemiparalysis is achieved.
文摘BACKGROUND: Transplanted mononuclear cell (MNC) of umbilical blood can survive in central nervous system (CNS) of host through blood brain barrier, differentiate into nerve cells, migrate to damaged site and integrate morphological structure and function with nerve cells of host so as to improve deficiencies of sensatory function, motor function and cognitive function and influence on stroke sequela. OBJECTIVE: To observe the vein transplantation of human umbilical cord blood stem cells (HUCBSC) for improving neurological function, limb function and activity of daily living of patients with stroke and evaluate the reliability. DESIGN: Self-controlled study. SETTING: Department of Neurosurgery, the Second People's Hospital of Zhengzhou City; Red-crossed Blood Center of Henan Province; Department of Neurosurgery, the Fist Affiliated Hospital of Zhengzhou University. PARTICIPANTS: A total of 10 patients with stroke sequela were selected from Department of Cerebral Surgery, the Second People's Hospital of Zhengzhou City from April to December 2005. There were 9 males and 1 female aged from 35 to 75 years with the mean age of 56 years. All of them were diagnosed with CT and MRI examination and coincidence with diagnostic criteria of stroke established by the Fourth National Academic Meeting for Cerebrovascular Disease. All patients provided informed consent. METHODS: 80-140 mL umbilical blood of term birth of newborn was selected hermetically and maintained in sterile plastic bag. And then, the blood was centrifugated at the speed of 1 500 r/min for 30 minutes at 22 ℃ in order to separate MNC, i.e., HUCBSC. In addition, after final diagnosis during hospitalization, stroke patients were perfused with HUCBSC through superficial vein of back of the hand. Each patient was averagely perfused with 6 portions of HUCBSC (cellular numbers ≥ 1×108/portion) and the interval between each portion was 1-7 days with the mean interval of 4 days. MAIN OUTCOME MEASURES: ① Neurological function of stroke patients was evaluated with neurological function deficiency (NFD) before treatment and at 3 months after treatment. The scale includes consciousness, level fix function, facial paralysis, language, muscle force of upper limbs, muscle force of lower limb and step function. The total scores ranged from 0 to 45; meanwhile, the lower the scores were, the better the neurological function was. ② Motor function of injured limbs was evaluated with Fugl-Meyer Assessment (FMA), including motor function of upper limbs, motor function of lower limbs, balance ability, sensory function and motion of joint. The total scores ranged from 0 to 226; meanwhile, the higher the scores were, the better the motor function of limbs was. ③ Activities of daily living (ADL) was evaluated with Barthel Index (BI), including having meals, taking a bath, dressing oneself, putting on clothes, walking in balance and stair activity. The total scores ranged from 0 to 100; meanwhile, the higher the scores were, the stronger the ADL was. RESULTS: A total of 10 patients were involved in the final analysis. After treatment, NFD of stroke patients was (10.9±5.09) points, which was lower than that before treatment [(25.4±6.09) points, t =8.213, P < 0.01]. In addition, after treatment, FMA and BI of stroke patients were (80.9±25.00) points and (81.1±15.93) points, respectively, which were higher than those before treatment [(31.9±21.85) points, (36.2±19.41) points, t =13.024, 13.670, P < 0.01]. Immuno-suppressive drugs were not used during the whole therapeutic procedure; moreover, immunological rejection and allergic reaction were not observed during the same period. CONCLUSION: Transplanting HUCBSC through superficial vein of back of the hand is regarded as a simple and safe method for the treatment of stroke sequela.
文摘Objective To investigate clinical effects of acupuncture method for dredging collaterals and resolving phlegm on stroke in Congo. Methods The patients in Congo China-Congo Friendship Hospital were randomly divided into an acupuncture group and a medicine group, 30 cases in each group. For the acupuncture group, Moiluoning injection was administrated by intravenous drip and acupuncture was given at Sishencong （四神聪 EX-HN 1）, Zhangwan （中脘 CV 12）, Fenglong （丰隆 ST 40） and Neiguan （内关 PC 6）, etc., once daily for 10 consecutive days as a course of treatment. For the medicine group, 20 mL Moiluoning or 500 mL low molecular Dextran injection was administrated by intravenous drip, once each day for 10 consecutive days as a course of treatment. After 3 therapeutic courses, clinical therapeutic effects were assessed. Results After treatment, the scores for nervous function were significantly decreased in the two groups （both P〈0.05）, with a significant difference between the two groups （P〈0.05）, the acupuncture group being superior to the medicine group; the effective rate （93.3%, 28/30） of the acupuncture group was significantly higher than that （80.0%, 24/30） of the medicine group （P〈0.05）. Conclusion Acupuncture with the method for dredging collaterals and resolving phlegm has a significant clinical effect on stroke.
文摘Objective: to study the effect and evaluation of Buyang Huanwu Decoction on sequela of cerebral apoplexy. Methods: According to the inclusion and exclusion criteria, 80 patients with sequela of cerebral apoplexy were selected from November 2018 to November 2020, grouping was completed according to the order of admission. The first 40 patients in the control group received conventional treatment, and the last 40 patients in the experimental group were combined with Buyang Huanwu Decoction for treatment, and the therapeutic effects were compared. Results: after the implementation of different treatment programs, the limb function of the experimental group was well recovered, and the daily living ability, cognitive function and neurologic impairment of the patients were significantly improved compared with the control group, with statistical significance (P < 0.05). Conclusion: routine acupuncture and Buyang Huanwu Decoction can effectively alleviate sequela, and the prognosis of patients with sequela is good. The indicators including daily recovery of limb function, cognitive function and neurological function are significantly improved, and the quality of life is significantly improved. It has the value of promotion and use.
文摘Objective： To describe the effect of acupuncture with a new acupoint prescription in treating dysphagia from a chronic stroke patient by fiberoptic endoscopic evaluation of swallowing （FEES）. Methods： A case of chronic dysphagic stroke patient was treated by acupuncture with 5 established acupoints, and assessed by FEES before and after 4-week treatments. Results： There is improvement in swallowing and speech function after acupuncture treatment. Conclusion： There is evidence showing that new acupuncture points maybe beneficial for dysphagic stroke patients.
