The stigmas of five species, Populus euphratica Oliv., P. alba L., P. simonii Carr., P. lasiocarpa Oliv. and P. nigra L. have been studied. Scanning electron microscopy re veals that exudates are present in the ...The stigmas of five species, Populus euphratica Oliv., P. alba L., P. simonii Carr., P. lasiocarpa Oliv. and P. nigra L. have been studied. Scanning electron microscopy re veals that exudates are present in the intercellular spaces, in the clefts between the multicel lular papillae and on the receptive surface. Release and movement of exudates can be visual ized when the fresh stigmas are stained with sudan Ⅲ and auramine O. Paraffin and semi thin resin sections of stigmas after glutaraldehyde osmium fixation evidence the lipidic nature of the exudates. Transmission electron microscopy reveals the glandular features of the stigmatic papillae cells, such as abundance of rough and smooth endoplasmic reticulum, polyribosomes, and well developed dictyosomes with secretory vesicles. Pellicle and epicuticular lamellate layers which have been considered as typical features of the dry type stigmas are also present in the species where stigmas appear extremely wet. It is concluded that stigmas in all of the five species are secretory at the receptive stage. Well developed generative and sperm cells were observed in the pollen tubes penetrating through the deep layers of the stigmatic tissue in the reciprocal crosses between P. euphratica and P. simonii, which indicated that there is no significant barrier in the stigma.展开更多
The aim of our study was to explore the antioxidant potential of Moroccan saffron stigmas(SS) and examine their performance as a natural antioxidant in enhancing the stability and quality properties of edible sunflowe...The aim of our study was to explore the antioxidant potential of Moroccan saffron stigmas(SS) and examine their performance as a natural antioxidant in enhancing the stability and quality properties of edible sunflower oil(SO), with a focus on understanding the critical importance of edible oil stability for predicting quality deterioration during storage. Bearing this in mind, our research was designed to compare the efficacy of three concentrations of dried SS(at 0.2%, 0.3%, and 0.6%) against tocobiol(a synthetic antioxidant) as a positive control(at 0.3% concentration). This comparison was conducted under three distinct storage conditions namely accelerated ageing(60 ℃), exposure to light at ambient temperature, and darkness, to evaluate their impact on preventing severe oxidation and extending oil shelf-life. Oxidation state evolution was evaluated through peroxide value(PV), free fatty acid(FFA), anisidine value(p-AV), K_(270)value(conjugated trienes), total oxidation index(TOTOX), iodine value(IV), and fatty acid composition(FA). Our results revealed notable differences in stability tracking parameters. Specifically, these parameters were higher in samples stored under accelerated conditions, followed by the samples stored in ambient light, while those stored in darkness showed the highest stability among the three storage conditions. Supplementation of sunflower oil with SS and tocobiol significantly enhanced its oxidation stability. Notably, SS exhibited exceptional effectiveness in stabilizing sunflower oil regardless of SS dose, with the highest efficacy observed at 0.6%. This was evidenced by the slower rate of oxidation parameters under various storage conditions, highlighting a superior antioxidant activity compared to both the non-enriched oil and tocobiol-enriched oil. Furthermore, saffron stigmas, used as a natural supplement,contributed to the preservation of polyunsaturated fatty acids, indicating its potential as a robust source of natural antioxidants in sunflower oil. These attributes position SS as a promising alternative to synthetic antioxidants, offering opportunities to enhance the nutritional quality and extend edible oil shelf-life.展开更多
RETHINKING GOOD VOCATIONAL EDUCATION Sanlian Lifeweek 12 January For its first 2026 cover story,Sanlian Lifeweek returns for the fourth time to the theme of“Good Vocational Education,”a deliberately unresolved quest...RETHINKING GOOD VOCATIONAL EDUCATION Sanlian Lifeweek 12 January For its first 2026 cover story,Sanlian Lifeweek returns for the fourth time to the theme of“Good Vocational Education,”a deliberately unresolved question that has guided its reporting since 2020.The magazine’s intent has never been to o!er a definitive answer,but to counter long-standing stigmas around vocational education by documenting real practices,dilemmas and possibilities on the ground.展开更多
Treatment adherence among people living with human immunodeficiency virus(PLWH)is a critical determinant of viral suppression and improved quality of life.Medication literacy,as a key factor influencing adherence,is i...Treatment adherence among people living with human immunodeficiency virus(PLWH)is a critical determinant of viral suppression and improved quality of life.Medication literacy,as a key factor influencing adherence,is itself shaped by various psychosocial variables.Existing studies suggest that human immunodeficiency virus(HIV)-related stigma,self-efficacy,and trust in healthcare providers serve as significant mediators in the relationship between health literacy and treatment adherence.This review systematically explores how medication literacy affects treatment adherence in PLWH through intermediary psychosocial mechanisms such as depression,anxiety,and social support.By synthesizing current evidence,we aim to inform the development of targeted psychosocial interventions to enhance treatment outcomes and quality of life for this population.Our findings provide an evidence-based foundation for nursing practice and support innovative strategies in comprehensive HIV care.展开更多
Objectives This study aimed to develop and preliminarily assess the quality of a Mindfulness Breast Care(MBC)App to reduce body image distress and stigma among breast cancer survivors(BCSs).Methods The development pro...Objectives This study aimed to develop and preliminarily assess the quality of a Mindfulness Breast Care(MBC)App to reduce body image distress and stigma among breast cancer survivors(BCSs).Methods The development process of the MBC App involved:1)establishing a research group;2)determining of the content of the MBC App based on Mindfulness-Based Cognitive Therapy and 3)technical exploitation and maintenance.A mixed-methods study was conducted.We selected ten BCSs by a convenience sampling method.After using the APP for three months,five assessed the quality using the Mobile App Rating Scale:User Version(uMARS)and another five were interviewed for process evaluation.Results The MBC App was developed with three modules:1)Library to provide health education information on body image,stigma,mindfulness,recovery and etc;2)Mindfulness Yoga to offer 12 Hatha yoga videos for daily practice;and 3)Mindfulness Practices to have 12 sessions of mindfulness videoconferences.Based on the uMARS data,the MBC App received high ratings for functionality(4.10±0.34),aesthetics(3.93±0.55),information quality(4.10±0.72),and perceived impact(4.03±0.96),as well as moderate ratings for engagement(3.72±0.94)and subjective quality(3.87±0.77).Participants indicated that the MBC App provided reliable knowledge,information,and emotional support.Recommendations from participants included categorizing knowledge in the Library Module,recording videoconferences of mindfulness practice,and adding discussion sessions in the videoconference.Afterward,we optimized the MBC App to enhance the user experience accordingly.Conclusions The MBC App offers online mindfulness interventions specifically for BCSs in China.The preliminary quality assessment indicates that the MBC App may be a promising tool for delivering mindfulness interventions to BCSs.展开更多
Background:Weight stigma is prevalent and has multiple sources,which have significant effects on individual,social,physical,and psychological health.This study evaluated the psychometric properties of the Thai version...Background:Weight stigma is prevalent and has multiple sources,which have significant effects on individual,social,physical,and psychological health.This study evaluated the psychometric properties of the Thai version of WeSEI to provide a valid tool to assess weight stigma in Thai young adults.Methods:A cross-sectional online survey recruited 517 Thai university students from October 2024 to May 2025.All participants completed demographic information and standardized self-reported instruments,including WeSEI,Depression,Anxiety,and Stress scale 21(DASS-21),Weight Self-Stigma Questionnaire(WSSQ),and Perceived Weight Stigma Scale(PWSS).The psychometric properties of the Thai version of WeSEI were examined via confirmatory factor analysis(CFA)with some validity indices.Results:The 7-factor structure of the Thai version of the WeSEI was supported across sex and weight status subgroups,indicating good construct validity.In addition,internal consistency(Cronbach’sα=0.972;McDonald’sω=0.972),convergent,and discriminant validity also indicated that the Thai version of the WeSEI had good psychometric properties and assessed weight stigma among young people in Thailand.Conclusions:Sound psychometric properties of the Thai adaptation of WeSEI allows the identification of various sources contributing to weight stigma and to identify those experiencing high levels of weight stigma.It also provides evidence to support targeted interventions to reduce weight stigma and its associated mental health impacts in further research.Further studies are necessary to explore the utilization of WeSEI for weight stigma in Thailand.展开更多
Bioethics is the argumentative discipline of decisions and actions that reduce conflicts of interest,dilemmas,or asymmetries between the parties involved in biomedical research.The objective of this work was to review...Bioethics is the argumentative discipline of decisions and actions that reduce conflicts of interest,dilemmas,or asymmetries between the parties involved in biomedical research.The objective of this work was to review and compare the dimensions used by bioethics in the communicative management of the pandemic,namely:risk,vulnerability,resilience,and stigma.A documentary,exploratory,transversal,and retrospective work was carried out with a sample of sources indexed in international repositories,considering the search by keywords and the publication period from 2020 to 2024.The results demonstrate the prevalence of supply,contagion,symptoms,and help against COVID-19.展开更多
In this editorial,I comment on the article conducted by Yang and Woo.Mental health in older adults remains underserved and underexamined,with final decades shaped by cumulative life stressors,chronic conditions,and so...In this editorial,I comment on the article conducted by Yang and Woo.Mental health in older adults remains underserved and underexamined,with final decades shaped by cumulative life stressors,chronic conditions,and social determinants that disproportionately affect marginalized communities.In this study,I would like to synthesize current evidence on the prevalence,presentation,and trajectories of mental health concerns among older adults,highlighting common challenges such as late-life depression,anxiety,cognitive concerns,and underutilization of care.I am going to examine barriers to outreach and treatment,including stigma,cultural and linguistic mismatches,access limitations,and gaps in geriatric mental health services.The analysis in the paper identifies promising pathways to improve outcomes:Community-engaged interventions,culturally tailored care models,integration of mental health with primary and geriatric care,and policy reforms to expand coverage and reduce disparities.As a conclusion,with actionable recommendations for clinicians,researchers,policymakers,and community organizations to break the silence,enhance early detection,and foster resilient aging through equitable,person-centered approaches.展开更多
HIV-related stigma,discrimination,and other forms of oppression can severely undermine adherence to antiretroviral therapy(ART)among people living with HIV[1].For example,Kerr et al.reveal that perceived discriminatio...HIV-related stigma,discrimination,and other forms of oppression can severely undermine adherence to antiretroviral therapy(ART)among people living with HIV[1].For example,Kerr et al.reveal that perceived discrimination based on sexual orientation in healthcare settings significantly reduces ART adherence[1].This highlights the urgent need for targeted strategies to address stigma,discrimination,and social marginalization,especially within healthcare facilities,to improve HIV care outcomes.展开更多
Objective:To understand the intertwined stigma experiences of the families of depression patients,providing a basis for implementing targeted interventions for depression patients and their families.To provide a basis...Objective:To understand the intertwined stigma experiences of the families of depression patients,providing a basis for implementing targeted interventions for depression patients and their families.To provide a basis for targeted interventions for patients with depression and their families.Methods:Based on the principle of data saturation,the family members of depressed patients in the mental health department and psychological outpatient clinic of a tertiary hospital in Hangzhou from March to May 2025 were selected by the purpose sampling method,and the semi-structured interview method was used to conduct in-depth interviews with the research subjects,and the Colaizzi 7-step analysis method was used for data analysis.Results:A total of 4 themes,and 8 sub-themes were extracted,namely cognitive responses(cognitive biases),emotional responses(internalized stigma and self-blame,feelings of shame,worries and concerns),behavioral responses(concealing the illness,social avoidance),and the potential impact of associated illness stigma(impact on the profession of relatives,emergence of internal family conflicts).Conclusion:Healthcare workers should gain an in-depth understanding of the associated stigma faced by the families of patients with depression and provide targeted psychological support.At the same time,there should be a call for society to pay positive and appropriate attention to patients with depression and their families,improving the families’understanding of the illness so that they can cope with the associated stigma in a positive manner.展开更多
Objectives:Schizophrenia is a profoundly stigmatized mental health condition,characterized by misconceptions that affect societal attitudes,policy development,and the lived experiences of individuals with the conditio...Objectives:Schizophrenia is a profoundly stigmatized mental health condition,characterized by misconceptions that affect societal attitudes,policy development,and the lived experiences of individuals with the condition.This study aimed to develop and validate a multidimensional scale for assessing societal stigma towards schizophrenia,while exploring how demographic factors influence such attitudes.Methods:Drawing on an extensive literature review and consultations,the study identified five domains of stigma:Workplace Capability,Intimate Relationships,Autonomy,Risk Perception,and Recovery.Using a two-phase methodology,a preliminary 38-itemscale was administered to 729 participants from the general Spanish population,refining the measure through descriptive and exploratory factor analysis.Subsequently,a revised 34-item scale was validated through confirmatory factor analysis with an independent sample of 417 participants.Results:The final model showed good fit(RMSEA=0.056,CFI=0.938,TLI=0.933)and strong internal consistency(α=0.73–0.86).Findings revealed that stigma was most pronounced in the domain of Autonomy(Mean=2.83,SD=0.91),reflecting pervasive doubts about individuals’ability to live independently and achieve meaningful integration into society.Stigma varied significantly across demographic variables,with higher levels reported among men,older individuals,married participants,and those outside health professions(p<0.01).Conversely,healthcare professionals,younger individuals,and those familiar with someone with schizophrenia generally reported less stigma(p<0.01).Conclusion:This study developed and validated a robust multidimensional scale for assessing societal stigma toward schizophrenia.The five-factor model—Workplace Capability,Intimate Relationships,Autonomy,Risk Perception,and Recovery—was empirically supported.Autonomy and Recovery emerged as themost stigmatized domains across the Spanish general population.The scale demonstrated strong psychometric properties and effectively captured stigma patterns linked to key sociodemographic variables.展开更多
Tomato reproductive success and yield are particularly vulnerable to the negative effect of heat stress leading to stigma exsertion(protrusion)and lower pollen viability,both interfering with fertilization.Thus,unders...Tomato reproductive success and yield are particularly vulnerable to the negative effect of heat stress leading to stigma exsertion(protrusion)and lower pollen viability,both interfering with fertilization.Thus,understanding the regulation of these two traits in tomato is crucial for the yield and quality of the crop.Here,we found that knocking out the tomato MADS-domain transcription factor FRUITFULL2(FUL2)function leads to a higher incidence of parthenocarpy in tomato.This phenotype was primarily due to impeded selfpollination as a consequence of the higher frequency of stigma exsertion and lower fertilization rates due to reduced pollen quality.Stigma exsertion in ful2 mutants,in contrast to heat stress-induced exsertion,was caused by style elongation,particularly in the younger flowers of a truss.Interestingly,Quantitative Trait Loci for style elongation,stigma exsertion,and pollen viability map close to the position of FUL2 on chromosome 3,making it a candidate gene underlying these QTLs.At the molecular level,ful2 mutant styles have higher expression of Style2.1 and SE3.1,which are known as positive regulators of style length.In addition,after reducing the impact of style exsertion and low pollen quality by manual pollination with wild-type pollen,ful2 mutants exhibited reduced fruit size independent of seed number.This study reveals the contributions of flower number,style length,and pollen quality,as affected by FUL2,to tomato fertility and fruit size.展开更多
As the population of older Asian Americans continues to grow rapidly,understanding their mental health needs has become increasingly critical.This literature review summarizes current issues,developments,and future di...As the population of older Asian Americans continues to grow rapidly,understanding their mental health needs has become increasingly critical.This literature review summarizes current issues,developments,and future directions in addressing the mental health challenges faced by older Asian Americans in the last five years.We briefly touch on the comparative prevalence of mental health disorders experienced by ethnic subgroups.Additionally,we review recent studies highlighting the role of the coronavirus disease 2019,racism,social support,cultural stigma,and self-rated health as significant factors influencing mental well-being of this population.We discuss the utilization of health services among older Asian Americans.We conclude with thoughts for future research,emphasizing the importance of longitudinal studies,consideration of diverse Asian American ethnic subgroups,and culturally sensitive diagnostic and treatment approaches.展开更多
Background:Existing Chinese stigma scales focus on the perceptions of people with mental illness(PMI)without assessing the general public’s attitudes toward integrating PMI into the community.Developing a valid and r...Background:Existing Chinese stigma scales focus on the perceptions of people with mental illness(PMI)without assessing the general public’s attitudes toward integrating PMI into the community.Developing a valid and reliable Chinese instrument measuring the attitude domain will be helpful to future research in this area.The current study aimed to validate a shortened Chinese version of the Community Attitudes towards the Mentally Ill Scale(C-CAMI-SF).Methods:Four hundred participants who are(1)Chinese;(2)aged 18 years and above;and(3)able to complete the Chinese questionnaire in a self-reported manner participated in the research.Principal component analysis was conducted to explore the factor structure of the scale.Internal consistency was examined using the Cronbach’s alpha coefficient.Three other questionnaires:Social Distance Scale(SDS),The Attribution Questionnaires-9-Item Version(AQ-9),and the Interpersonal Support Evaluation List-12(ISEL-12),were used to examine the convergent and divergent validity of the scale.Results:Finally,seventeen items were retained in the C-CAMI-SF with factor loadings ranging from 0.51 to 0.81.The Cronbach’s alpha coefficients of the scale were revealed to be 0.58,0.57,0.75,and 0.68 for each subscale,respectively.Although the first two values fall just short of the conventional 0.70 benchmark,this is still acceptable for a unidimensional subscale comprising only 3–4 items.Significant correlations(p<0.05)were obtained in the expected directions between the C-CAMI-SF and the other three validity check scales.Conclusion:The 17-item C-CAMI-SF validated in the current study demonstrated good psychometric properties and conceptual coherence.It also provided implications for future stigma reduction interventions.展开更多
Ebola virus disease(EVD)is a rare tropical disease,with case fatality ranging from 25%to 90%[1].As this infection is transmitted between humans via close contact,this led to the emergence of stigma against people who ...Ebola virus disease(EVD)is a rare tropical disease,with case fatality ranging from 25%to 90%[1].As this infection is transmitted between humans via close contact,this led to the emergence of stigma against people who were diagnosed with the infection[1,2].The latest outbreak of EVD was caused by the Sudan Ebola virus that affected nine districts of Uganda,and accounted for 164 cases and 77 deaths[3].Even though it was declared that this outbreak has ended,the health authorities have maintained surveillance to quickly detect and effectively respond to any new cases[3].In addition,a follow-up program has been initiated to support disease survivors and neighboring nations are instructed to be on high alert[3].The purpose of the current article was to justify the need to extend mental health support to the survivors of EVD outbreaks,identify the existing barriers which limit the delivery of mental healthcare services,and propose remedial measures to overcome these earmarked barriers.展开更多
Objective:This study has the objective to offer a thorough overview of the current state and future research possibilities regarding the social stigma of tuberculosis(TB).Given the growing volume and variety of resear...Objective:This study has the objective to offer a thorough overview of the current state and future research possibilities regarding the social stigma of tuberculosis(TB).Given the growing volume and variety of research in this field,a quantitative approach is essential for mapping existing themes and pinpointing potential areas for further investigation.To accomplish this,a bibliometric and content analysis was performed to explore the current literature and emphasize key themes and future directions.Methods:The study examines 770 bibliographic records from Scopus and visualizes the results of the bibliometric analysis using co-occurrence and thematic map analyses with VOSviewer and Tableau Public software.Additionally,a content analysis was conducted based on the findings from the co-occurrence analysis.Results:The findings indicate a notable rise in publications and citations related to the social stigma of TB,with prominent research topics including healthcare workers,social support,mobile health technology(mHealth),nursing,and attitudes.Emerging areas of research encompass epidemiology,public health,patient delays,multidrug-resistant TB(MDR-TB),corona virus disease 2019,and mHealth.Future studies might concentrate on the factors leading to patient delays,as well as the development of diagnostic tools and effective treatment regimens for MDR-TB cases.Conclusion:This study offers important insights into the current state of social stigma in TB research and identifies promising areas for future investigation.By addressing these research gaps and refining methodological approaches,researchers can strengthen initiatives to combat TB stigma,ultimately resulting in more effective treatments and improved adherence among TB patients.展开更多
Background:Limited mental health literacy(MHL)among university service providers is a significant obstacle to effective psychological support.Developing and systematically assessing evidence-based interventions is an ...Background:Limited mental health literacy(MHL)among university service providers is a significant obstacle to effective psychological support.Developing and systematically assessing evidence-based interventions is an urgent priority,particularly in low-and middle-income countries(LMICs).This study aimed to evaluate the effectiveness of the Acceptance&Commitment to Empowerment:Linking Youths AND‘Xin’(Hearts)(ACE-LYNX)intervention in reducing stigma,improving psychological well-being,and enhancing the MHL and empowerment practices of university mental health providers in China.Methods:A total of 124 trained providers participated in this longitudinal study.Quantitative data were collected at baseline,immediately post-intervention,and three-month follow-up using the validated scale(CAMI,DASS-21)and weekly activity logs recording empowerment practices.Generalized estimating equations(GEEs)and qualitative content analysis were used for data analysis.Results:Quantitative analysis showed a significant reduction in stigma immediately postintervention,particularly in the Social Restriction subscale(β=1.35,p<0.001),though this effect diminished by the 3-month follow-up(β=1.80,p=0.001).Notably,a lasting reduction in the providers’stress levels was maintained.Activity logs showed the highest level of engagement at the individual level(51.4%),followed by group level(32.0%),organizational level(10.5%),and community level(6.1%).Qualitative analysis revealed three themes:Skill-based empowerment enhances professional efficacy,embedded interventions expand service boundaries,and organizational empowerment fosters sustainability.Conclusions:This dual-focus ACE-LYNX intervention effectively improved MHL and both attitudinal and functional competencies among providers.It provides a scalable framework for fostering sustainable and inclusive campus mental health ecosystems,with significant implication for enhance psychological services in resource-constrained educational settings.展开更多
This minireview focuses on psychological distress and treatment adherence-issues in patients with chronic hepatitis B(CHB).It begins by discussing the epidemiology and disease burden of CHB,and addresses the relations...This minireview focuses on psychological distress and treatment adherence-issues in patients with chronic hepatitis B(CHB).It begins by discussing the epidemiology and disease burden of CHB,and addresses the relationship between psychological distress and treatment adherence.Next,it delves into the current status and risk factors for psychological distress among patients with CHB,and explores the challenges and risk factors related to treatment adherence.Subsequently,it explores the development and implementation of integrated nursing strategies,including psychological interventions and support,self-efficacy enhancement strategies,social support-system optimization,personalized medical care,and technological innovation.Finally,it highlights the limitations of current interventions and clarifies future research priorities.This minireview aims to provide a comprehensive theoretical basis and practical guidance for improving treatment outcomes and quality of life of patients with CHB.In summary,we reveal that psychological distress significantly impacts treatment adherence in patients with CHB and that it is essential to adopt integrated nursing strategies to address these challenges.These findings highlight the need to consider the psychological states of individuals and develop targeted interventions to improve treatment outcomes.展开更多
[Objective] This study was to use reverse genic male sterile FHS better in field production. [Method] Low energy nitrogen ion beam was taken as a mutation source to conduct mutagenic treatment for indica rice 99-02 an...[Objective] This study was to use reverse genic male sterile FHS better in field production. [Method] Low energy nitrogen ion beam was taken as a mutation source to conduct mutagenic treatment for indica rice 99-02 and the mutant FHS with special fertility that was isolated from their offspring. Some characteristics such as flowering habit and stigma exsertion rate of FHS were observed in this experiment. [Result] The reverse genic sterile rice FHS had an obvious peak flowering stage from 10:00 to 10:30, while the second peak flowering was from August 5 to August 10. Compared with PA64S, FHS flowered early and its flowering time was concentrated, showing that it is for seed propagation. The stigma exsertion rate of FHS was 85.8% and low exsertion rate was good for the purity of seed. [Conclusion] The reverse genic sterile rice FHS had good value in use, besides, it could also be used as comparison material for studying fertility alternation mechanism of photoperiod sensitive genic male sterile rice.展开更多
[Objective] This study aimed to investigate the correlation between stigma characteristics and outcrossing rate of photo-thermo sensitive genic male sterile（PTGMS） rice lines. [Method] The stigma exsertion rate, sti...[Objective] This study aimed to investigate the correlation between stigma characteristics and outcrossing rate of photo-thermo sensitive genic male sterile（PTGMS） rice lines. [Method] The stigma exsertion rate, stigma size and stigma vitality of Chuang 5S, Yun 9S, Peiai 64 S, P88 S and Y58 S were analyzed. Using R608 as a male parent, outcrossing rate of these five PTGMS lines was determined. [Result]There were differences in stigma exsertion rate, stigma size and stigma vitality among five PTGMS lines. P88 S exhibited the best stigma characteristics and relatively strong stigma vitality, with the stigma exsertion rate of 95.94%, stigma vitality coefficient of 2.71, outcrossing rate of 84.02% in the field. Peiai 64 s had the minimum stigma length（2.41 mm） and stigma width（1.10 mm） and the weakest stigma vitality, with the stigma exsertion rate of 93.04%, outcrossing rate of 65.47%. Yun 9S,Y58 S and Chuang 5S displayed medium stigma characteristics, among which Yun9 S exhibited higher outcrossing rate than other two PTGMS lines. Correlation analysis showed that stigma exsertion rate, stigma length, stigma width, stigma area and stigma volume were significantly correlated to outcrossing rate（P〈0.05）, with correlation coefficients of 0.897, 0.934, 0.934, 0.939 and 0.937, respectively. However,there was no significant correlation between stigma vitality coefficient and outcrossing rate. [Conclusion] Based on stigma characteristics of five PTGMS lines, auxiliary pollination measures should be adopted reasonably to save production costs and improve hybrid rice seed yield.展开更多
基金the NationalNaturalScience Foundation ofChina (NNSFC)
文摘The stigmas of five species, Populus euphratica Oliv., P. alba L., P. simonii Carr., P. lasiocarpa Oliv. and P. nigra L. have been studied. Scanning electron microscopy re veals that exudates are present in the intercellular spaces, in the clefts between the multicel lular papillae and on the receptive surface. Release and movement of exudates can be visual ized when the fresh stigmas are stained with sudan Ⅲ and auramine O. Paraffin and semi thin resin sections of stigmas after glutaraldehyde osmium fixation evidence the lipidic nature of the exudates. Transmission electron microscopy reveals the glandular features of the stigmatic papillae cells, such as abundance of rough and smooth endoplasmic reticulum, polyribosomes, and well developed dictyosomes with secretory vesicles. Pellicle and epicuticular lamellate layers which have been considered as typical features of the dry type stigmas are also present in the species where stigmas appear extremely wet. It is concluded that stigmas in all of the five species are secretory at the receptive stage. Well developed generative and sperm cells were observed in the pollen tubes penetrating through the deep layers of the stigmatic tissue in the reciprocal crosses between P. euphratica and P. simonii, which indicated that there is no significant barrier in the stigma.
文摘The aim of our study was to explore the antioxidant potential of Moroccan saffron stigmas(SS) and examine their performance as a natural antioxidant in enhancing the stability and quality properties of edible sunflower oil(SO), with a focus on understanding the critical importance of edible oil stability for predicting quality deterioration during storage. Bearing this in mind, our research was designed to compare the efficacy of three concentrations of dried SS(at 0.2%, 0.3%, and 0.6%) against tocobiol(a synthetic antioxidant) as a positive control(at 0.3% concentration). This comparison was conducted under three distinct storage conditions namely accelerated ageing(60 ℃), exposure to light at ambient temperature, and darkness, to evaluate their impact on preventing severe oxidation and extending oil shelf-life. Oxidation state evolution was evaluated through peroxide value(PV), free fatty acid(FFA), anisidine value(p-AV), K_(270)value(conjugated trienes), total oxidation index(TOTOX), iodine value(IV), and fatty acid composition(FA). Our results revealed notable differences in stability tracking parameters. Specifically, these parameters were higher in samples stored under accelerated conditions, followed by the samples stored in ambient light, while those stored in darkness showed the highest stability among the three storage conditions. Supplementation of sunflower oil with SS and tocobiol significantly enhanced its oxidation stability. Notably, SS exhibited exceptional effectiveness in stabilizing sunflower oil regardless of SS dose, with the highest efficacy observed at 0.6%. This was evidenced by the slower rate of oxidation parameters under various storage conditions, highlighting a superior antioxidant activity compared to both the non-enriched oil and tocobiol-enriched oil. Furthermore, saffron stigmas, used as a natural supplement,contributed to the preservation of polyunsaturated fatty acids, indicating its potential as a robust source of natural antioxidants in sunflower oil. These attributes position SS as a promising alternative to synthetic antioxidants, offering opportunities to enhance the nutritional quality and extend edible oil shelf-life.
文摘RETHINKING GOOD VOCATIONAL EDUCATION Sanlian Lifeweek 12 January For its first 2026 cover story,Sanlian Lifeweek returns for the fourth time to the theme of“Good Vocational Education,”a deliberately unresolved question that has guided its reporting since 2020.The magazine’s intent has never been to o!er a definitive answer,but to counter long-standing stigmas around vocational education by documenting real practices,dilemmas and possibilities on the ground.
基金Supported by Taizhou Municipal Hospital,No.2025JK317 and No.2025JK318.
文摘Treatment adherence among people living with human immunodeficiency virus(PLWH)is a critical determinant of viral suppression and improved quality of life.Medication literacy,as a key factor influencing adherence,is itself shaped by various psychosocial variables.Existing studies suggest that human immunodeficiency virus(HIV)-related stigma,self-efficacy,and trust in healthcare providers serve as significant mediators in the relationship between health literacy and treatment adherence.This review systematically explores how medication literacy affects treatment adherence in PLWH through intermediary psychosocial mechanisms such as depression,anxiety,and social support.By synthesizing current evidence,we aim to inform the development of targeted psychosocial interventions to enhance treatment outcomes and quality of life for this population.Our findings provide an evidence-based foundation for nursing practice and support innovative strategies in comprehensive HIV care.
基金supported by the National Natural Science Foundation of China(No.71974162 and No.7231101009).
文摘Objectives This study aimed to develop and preliminarily assess the quality of a Mindfulness Breast Care(MBC)App to reduce body image distress and stigma among breast cancer survivors(BCSs).Methods The development process of the MBC App involved:1)establishing a research group;2)determining of the content of the MBC App based on Mindfulness-Based Cognitive Therapy and 3)technical exploitation and maintenance.A mixed-methods study was conducted.We selected ten BCSs by a convenience sampling method.After using the APP for three months,five assessed the quality using the Mobile App Rating Scale:User Version(uMARS)and another five were interviewed for process evaluation.Results The MBC App was developed with three modules:1)Library to provide health education information on body image,stigma,mindfulness,recovery and etc;2)Mindfulness Yoga to offer 12 Hatha yoga videos for daily practice;and 3)Mindfulness Practices to have 12 sessions of mindfulness videoconferences.Based on the uMARS data,the MBC App received high ratings for functionality(4.10±0.34),aesthetics(3.93±0.55),information quality(4.10±0.72),and perceived impact(4.03±0.96),as well as moderate ratings for engagement(3.72±0.94)and subjective quality(3.87±0.77).Participants indicated that the MBC App provided reliable knowledge,information,and emotional support.Recommendations from participants included categorizing knowledge in the Library Module,recording videoconferences of mindfulness practice,and adding discussion sessions in the videoconference.Afterward,we optimized the MBC App to enhance the user experience accordingly.Conclusions The MBC App offers online mindfulness interventions specifically for BCSs in China.The preliminary quality assessment indicates that the MBC App may be a promising tool for delivering mindfulness interventions to BCSs.
基金Hualien Tzu-Chi Hospital of the Buddhist Tzu Chi Medical Foundation.
文摘Background:Weight stigma is prevalent and has multiple sources,which have significant effects on individual,social,physical,and psychological health.This study evaluated the psychometric properties of the Thai version of WeSEI to provide a valid tool to assess weight stigma in Thai young adults.Methods:A cross-sectional online survey recruited 517 Thai university students from October 2024 to May 2025.All participants completed demographic information and standardized self-reported instruments,including WeSEI,Depression,Anxiety,and Stress scale 21(DASS-21),Weight Self-Stigma Questionnaire(WSSQ),and Perceived Weight Stigma Scale(PWSS).The psychometric properties of the Thai version of WeSEI were examined via confirmatory factor analysis(CFA)with some validity indices.Results:The 7-factor structure of the Thai version of the WeSEI was supported across sex and weight status subgroups,indicating good construct validity.In addition,internal consistency(Cronbach’sα=0.972;McDonald’sω=0.972),convergent,and discriminant validity also indicated that the Thai version of the WeSEI had good psychometric properties and assessed weight stigma among young people in Thailand.Conclusions:Sound psychometric properties of the Thai adaptation of WeSEI allows the identification of various sources contributing to weight stigma and to identify those experiencing high levels of weight stigma.It also provides evidence to support targeted interventions to reduce weight stigma and its associated mental health impacts in further research.Further studies are necessary to explore the utilization of WeSEI for weight stigma in Thailand.
文摘Bioethics is the argumentative discipline of decisions and actions that reduce conflicts of interest,dilemmas,or asymmetries between the parties involved in biomedical research.The objective of this work was to review and compare the dimensions used by bioethics in the communicative management of the pandemic,namely:risk,vulnerability,resilience,and stigma.A documentary,exploratory,transversal,and retrospective work was carried out with a sample of sources indexed in international repositories,considering the search by keywords and the publication period from 2020 to 2024.The results demonstrate the prevalence of supply,contagion,symptoms,and help against COVID-19.
文摘In this editorial,I comment on the article conducted by Yang and Woo.Mental health in older adults remains underserved and underexamined,with final decades shaped by cumulative life stressors,chronic conditions,and social determinants that disproportionately affect marginalized communities.In this study,I would like to synthesize current evidence on the prevalence,presentation,and trajectories of mental health concerns among older adults,highlighting common challenges such as late-life depression,anxiety,cognitive concerns,and underutilization of care.I am going to examine barriers to outreach and treatment,including stigma,cultural and linguistic mismatches,access limitations,and gaps in geriatric mental health services.The analysis in the paper identifies promising pathways to improve outcomes:Community-engaged interventions,culturally tailored care models,integration of mental health with primary and geriatric care,and policy reforms to expand coverage and reduce disparities.As a conclusion,with actionable recommendations for clinicians,researchers,policymakers,and community organizations to break the silence,enhance early detection,and foster resilient aging through equitable,person-centered approaches.
文摘HIV-related stigma,discrimination,and other forms of oppression can severely undermine adherence to antiretroviral therapy(ART)among people living with HIV[1].For example,Kerr et al.reveal that perceived discrimination based on sexual orientation in healthcare settings significantly reduces ART adherence[1].This highlights the urgent need for targeted strategies to address stigma,discrimination,and social marginalization,especially within healthcare facilities,to improve HIV care outcomes.
基金The 2025 Diligent Research and Innovation and Entrepreneurship Project of Hangzhou Normal University。
文摘Objective:To understand the intertwined stigma experiences of the families of depression patients,providing a basis for implementing targeted interventions for depression patients and their families.To provide a basis for targeted interventions for patients with depression and their families.Methods:Based on the principle of data saturation,the family members of depressed patients in the mental health department and psychological outpatient clinic of a tertiary hospital in Hangzhou from March to May 2025 were selected by the purpose sampling method,and the semi-structured interview method was used to conduct in-depth interviews with the research subjects,and the Colaizzi 7-step analysis method was used for data analysis.Results:A total of 4 themes,and 8 sub-themes were extracted,namely cognitive responses(cognitive biases),emotional responses(internalized stigma and self-blame,feelings of shame,worries and concerns),behavioral responses(concealing the illness,social avoidance),and the potential impact of associated illness stigma(impact on the profession of relatives,emergence of internal family conflicts).Conclusion:Healthcare workers should gain an in-depth understanding of the associated stigma faced by the families of patients with depression and provide targeted psychological support.At the same time,there should be a call for society to pay positive and appropriate attention to patients with depression and their families,improving the families’understanding of the illness so that they can cope with the associated stigma in a positive manner.
文摘Objectives:Schizophrenia is a profoundly stigmatized mental health condition,characterized by misconceptions that affect societal attitudes,policy development,and the lived experiences of individuals with the condition.This study aimed to develop and validate a multidimensional scale for assessing societal stigma towards schizophrenia,while exploring how demographic factors influence such attitudes.Methods:Drawing on an extensive literature review and consultations,the study identified five domains of stigma:Workplace Capability,Intimate Relationships,Autonomy,Risk Perception,and Recovery.Using a two-phase methodology,a preliminary 38-itemscale was administered to 729 participants from the general Spanish population,refining the measure through descriptive and exploratory factor analysis.Subsequently,a revised 34-item scale was validated through confirmatory factor analysis with an independent sample of 417 participants.Results:The final model showed good fit(RMSEA=0.056,CFI=0.938,TLI=0.933)and strong internal consistency(α=0.73–0.86).Findings revealed that stigma was most pronounced in the domain of Autonomy(Mean=2.83,SD=0.91),reflecting pervasive doubts about individuals’ability to live independently and achieve meaningful integration into society.Stigma varied significantly across demographic variables,with higher levels reported among men,older individuals,married participants,and those outside health professions(p<0.01).Conversely,healthcare professionals,younger individuals,and those familiar with someone with schizophrenia generally reported less stigma(p<0.01).Conclusion:This study developed and validated a robust multidimensional scale for assessing societal stigma toward schizophrenia.The five-factor model—Workplace Capability,Intimate Relationships,Autonomy,Risk Perception,and Recovery—was empirically supported.Autonomy and Recovery emerged as themost stigmatized domains across the Spanish general population.The scale demonstrated strong psychometric properties and effectively captured stigma patterns linked to key sociodemographic variables.
基金supported by a fellowship from the China Scholarship Council(CSC),award nr.202106300012 to X.W.from EU-RISE Evofruland:grant agreement no.101007738 to X.W.
文摘Tomato reproductive success and yield are particularly vulnerable to the negative effect of heat stress leading to stigma exsertion(protrusion)and lower pollen viability,both interfering with fertilization.Thus,understanding the regulation of these two traits in tomato is crucial for the yield and quality of the crop.Here,we found that knocking out the tomato MADS-domain transcription factor FRUITFULL2(FUL2)function leads to a higher incidence of parthenocarpy in tomato.This phenotype was primarily due to impeded selfpollination as a consequence of the higher frequency of stigma exsertion and lower fertilization rates due to reduced pollen quality.Stigma exsertion in ful2 mutants,in contrast to heat stress-induced exsertion,was caused by style elongation,particularly in the younger flowers of a truss.Interestingly,Quantitative Trait Loci for style elongation,stigma exsertion,and pollen viability map close to the position of FUL2 on chromosome 3,making it a candidate gene underlying these QTLs.At the molecular level,ful2 mutant styles have higher expression of Style2.1 and SE3.1,which are known as positive regulators of style length.In addition,after reducing the impact of style exsertion and low pollen quality by manual pollination with wild-type pollen,ful2 mutants exhibited reduced fruit size independent of seed number.This study reveals the contributions of flower number,style length,and pollen quality,as affected by FUL2,to tomato fertility and fruit size.
文摘As the population of older Asian Americans continues to grow rapidly,understanding their mental health needs has become increasingly critical.This literature review summarizes current issues,developments,and future directions in addressing the mental health challenges faced by older Asian Americans in the last five years.We briefly touch on the comparative prevalence of mental health disorders experienced by ethnic subgroups.Additionally,we review recent studies highlighting the role of the coronavirus disease 2019,racism,social support,cultural stigma,and self-rated health as significant factors influencing mental well-being of this population.We discuss the utilization of health services among older Asian Americans.We conclude with thoughts for future research,emphasizing the importance of longitudinal studies,consideration of diverse Asian American ethnic subgroups,and culturally sensitive diagnostic and treatment approaches.
文摘Background:Existing Chinese stigma scales focus on the perceptions of people with mental illness(PMI)without assessing the general public’s attitudes toward integrating PMI into the community.Developing a valid and reliable Chinese instrument measuring the attitude domain will be helpful to future research in this area.The current study aimed to validate a shortened Chinese version of the Community Attitudes towards the Mentally Ill Scale(C-CAMI-SF).Methods:Four hundred participants who are(1)Chinese;(2)aged 18 years and above;and(3)able to complete the Chinese questionnaire in a self-reported manner participated in the research.Principal component analysis was conducted to explore the factor structure of the scale.Internal consistency was examined using the Cronbach’s alpha coefficient.Three other questionnaires:Social Distance Scale(SDS),The Attribution Questionnaires-9-Item Version(AQ-9),and the Interpersonal Support Evaluation List-12(ISEL-12),were used to examine the convergent and divergent validity of the scale.Results:Finally,seventeen items were retained in the C-CAMI-SF with factor loadings ranging from 0.51 to 0.81.The Cronbach’s alpha coefficients of the scale were revealed to be 0.58,0.57,0.75,and 0.68 for each subscale,respectively.Although the first two values fall just short of the conventional 0.70 benchmark,this is still acceptable for a unidimensional subscale comprising only 3–4 items.Significant correlations(p<0.05)were obtained in the expected directions between the C-CAMI-SF and the other three validity check scales.Conclusion:The 17-item C-CAMI-SF validated in the current study demonstrated good psychometric properties and conceptual coherence.It also provided implications for future stigma reduction interventions.
文摘Ebola virus disease(EVD)is a rare tropical disease,with case fatality ranging from 25%to 90%[1].As this infection is transmitted between humans via close contact,this led to the emergence of stigma against people who were diagnosed with the infection[1,2].The latest outbreak of EVD was caused by the Sudan Ebola virus that affected nine districts of Uganda,and accounted for 164 cases and 77 deaths[3].Even though it was declared that this outbreak has ended,the health authorities have maintained surveillance to quickly detect and effectively respond to any new cases[3].In addition,a follow-up program has been initiated to support disease survivors and neighboring nations are instructed to be on high alert[3].The purpose of the current article was to justify the need to extend mental health support to the survivors of EVD outbreaks,identify the existing barriers which limit the delivery of mental healthcare services,and propose remedial measures to overcome these earmarked barriers.
文摘Objective:This study has the objective to offer a thorough overview of the current state and future research possibilities regarding the social stigma of tuberculosis(TB).Given the growing volume and variety of research in this field,a quantitative approach is essential for mapping existing themes and pinpointing potential areas for further investigation.To accomplish this,a bibliometric and content analysis was performed to explore the current literature and emphasize key themes and future directions.Methods:The study examines 770 bibliographic records from Scopus and visualizes the results of the bibliometric analysis using co-occurrence and thematic map analyses with VOSviewer and Tableau Public software.Additionally,a content analysis was conducted based on the findings from the co-occurrence analysis.Results:The findings indicate a notable rise in publications and citations related to the social stigma of TB,with prominent research topics including healthcare workers,social support,mobile health technology(mHealth),nursing,and attitudes.Emerging areas of research encompass epidemiology,public health,patient delays,multidrug-resistant TB(MDR-TB),corona virus disease 2019,and mHealth.Future studies might concentrate on the factors leading to patient delays,as well as the development of diagnostic tools and effective treatment regimens for MDR-TB cases.Conclusion:This study offers important insights into the current state of social stigma in TB research and identifies promising areas for future investigation.By addressing these research gaps and refining methodological approaches,researchers can strengthen initiatives to combat TB stigma,ultimately resulting in more effective treatments and improved adherence among TB patients.
基金funded by the National Natural Science Foundation of China(NSFC,grant 81761128033)the Canadian Institutes of Health Research(CIHR,FRN 154986)through the Collaborative Health Program of the Global Alliance for Chronic Disease(GACD).
文摘Background:Limited mental health literacy(MHL)among university service providers is a significant obstacle to effective psychological support.Developing and systematically assessing evidence-based interventions is an urgent priority,particularly in low-and middle-income countries(LMICs).This study aimed to evaluate the effectiveness of the Acceptance&Commitment to Empowerment:Linking Youths AND‘Xin’(Hearts)(ACE-LYNX)intervention in reducing stigma,improving psychological well-being,and enhancing the MHL and empowerment practices of university mental health providers in China.Methods:A total of 124 trained providers participated in this longitudinal study.Quantitative data were collected at baseline,immediately post-intervention,and three-month follow-up using the validated scale(CAMI,DASS-21)and weekly activity logs recording empowerment practices.Generalized estimating equations(GEEs)and qualitative content analysis were used for data analysis.Results:Quantitative analysis showed a significant reduction in stigma immediately postintervention,particularly in the Social Restriction subscale(β=1.35,p<0.001),though this effect diminished by the 3-month follow-up(β=1.80,p=0.001).Notably,a lasting reduction in the providers’stress levels was maintained.Activity logs showed the highest level of engagement at the individual level(51.4%),followed by group level(32.0%),organizational level(10.5%),and community level(6.1%).Qualitative analysis revealed three themes:Skill-based empowerment enhances professional efficacy,embedded interventions expand service boundaries,and organizational empowerment fosters sustainability.Conclusions:This dual-focus ACE-LYNX intervention effectively improved MHL and both attitudinal and functional competencies among providers.It provides a scalable framework for fostering sustainable and inclusive campus mental health ecosystems,with significant implication for enhance psychological services in resource-constrained educational settings.
文摘This minireview focuses on psychological distress and treatment adherence-issues in patients with chronic hepatitis B(CHB).It begins by discussing the epidemiology and disease burden of CHB,and addresses the relationship between psychological distress and treatment adherence.Next,it delves into the current status and risk factors for psychological distress among patients with CHB,and explores the challenges and risk factors related to treatment adherence.Subsequently,it explores the development and implementation of integrated nursing strategies,including psychological interventions and support,self-efficacy enhancement strategies,social support-system optimization,personalized medical care,and technological innovation.Finally,it highlights the limitations of current interventions and clarifies future research priorities.This minireview aims to provide a comprehensive theoretical basis and practical guidance for improving treatment outcomes and quality of life of patients with CHB.In summary,we reveal that psychological distress significantly impacts treatment adherence in patients with CHB and that it is essential to adopt integrated nursing strategies to address these challenges.These findings highlight the need to consider the psychological states of individuals and develop targeted interventions to improve treatment outcomes.
文摘[Objective] This study was to use reverse genic male sterile FHS better in field production. [Method] Low energy nitrogen ion beam was taken as a mutation source to conduct mutagenic treatment for indica rice 99-02 and the mutant FHS with special fertility that was isolated from their offspring. Some characteristics such as flowering habit and stigma exsertion rate of FHS were observed in this experiment. [Result] The reverse genic sterile rice FHS had an obvious peak flowering stage from 10:00 to 10:30, while the second peak flowering was from August 5 to August 10. Compared with PA64S, FHS flowered early and its flowering time was concentrated, showing that it is for seed propagation. The stigma exsertion rate of FHS was 85.8% and low exsertion rate was good for the purity of seed. [Conclusion] The reverse genic sterile rice FHS had good value in use, besides, it could also be used as comparison material for studying fertility alternation mechanism of photoperiod sensitive genic male sterile rice.
基金Supported by National Science and Technology Support Program of China(2014BAD06B07)~~
文摘[Objective] This study aimed to investigate the correlation between stigma characteristics and outcrossing rate of photo-thermo sensitive genic male sterile（PTGMS） rice lines. [Method] The stigma exsertion rate, stigma size and stigma vitality of Chuang 5S, Yun 9S, Peiai 64 S, P88 S and Y58 S were analyzed. Using R608 as a male parent, outcrossing rate of these five PTGMS lines was determined. [Result]There were differences in stigma exsertion rate, stigma size and stigma vitality among five PTGMS lines. P88 S exhibited the best stigma characteristics and relatively strong stigma vitality, with the stigma exsertion rate of 95.94%, stigma vitality coefficient of 2.71, outcrossing rate of 84.02% in the field. Peiai 64 s had the minimum stigma length（2.41 mm） and stigma width（1.10 mm） and the weakest stigma vitality, with the stigma exsertion rate of 93.04%, outcrossing rate of 65.47%. Yun 9S,Y58 S and Chuang 5S displayed medium stigma characteristics, among which Yun9 S exhibited higher outcrossing rate than other two PTGMS lines. Correlation analysis showed that stigma exsertion rate, stigma length, stigma width, stigma area and stigma volume were significantly correlated to outcrossing rate（P〈0.05）, with correlation coefficients of 0.897, 0.934, 0.934, 0.939 and 0.937, respectively. However,there was no significant correlation between stigma vitality coefficient and outcrossing rate. [Conclusion] Based on stigma characteristics of five PTGMS lines, auxiliary pollination measures should be adopted reasonably to save production costs and improve hybrid rice seed yield.
