Personalized healthcare monitoring is a transformative tool for preventing potential risks and enhancing health status,particularly through molecular-level insights.Advances in nanotechnology,smart devices,and artific...Personalized healthcare monitoring is a transformative tool for preventing potential risks and enhancing health status,particularly through molecular-level insights.Advances in nanotechnology,smart devices,and artificial intelligence(AI)have revolutionized personalized healthcare,especially in point-of-care testing(POCT),enabling early detection and timely intervention.Recently,surface-enhanced Raman spectroscopy(SERS)technology,particularly with flexible chips,has shown immense promise in this field due to its in situ,rapid,specific,and efficient detection capabilities.In this review,we highlight recent advancements in flexible SERS chips for personalized healthcare monitoring,demonstrating their effectiveness in target sampling and detection.Importantly,we provide a comprehensive overview of potential applications of flexible SERS chips in personalized healthcare,address current challenges,and propose future development directions.We also explore the future development of miniaturized Raman devices to broaden their applications in personalized healthcare monitoring.Additionally,we underscore the important role of AI in enhancing data processing and analysis.Our aim is to offer a thorough guide on integrating SERS into personalized healthcare monitoring,promising a new era of health management.展开更多
基金T.Q.acknowledges the National Natural Science Foundation of China(grant no.12374370)X.F.acknowledges the National Natural Science Foundation of China(grant no.12404451)+3 种基金the Natural Science Foundation of Jiangsu Province(grant no.BK20230807)Jiangsu Funding Program for Excellent Postdoctoral Talent(grant no.2024ZB532)the Postdoctoral Fellowship Program of CPSF(grant no.GZC20240264)Q.H.acknowledges the Open Research Fund of Key Laboratory of Quantum Materials and Devices(Southeast University),Ministry of Education.
文摘Personalized healthcare monitoring is a transformative tool for preventing potential risks and enhancing health status,particularly through molecular-level insights.Advances in nanotechnology,smart devices,and artificial intelligence(AI)have revolutionized personalized healthcare,especially in point-of-care testing(POCT),enabling early detection and timely intervention.Recently,surface-enhanced Raman spectroscopy(SERS)technology,particularly with flexible chips,has shown immense promise in this field due to its in situ,rapid,specific,and efficient detection capabilities.In this review,we highlight recent advancements in flexible SERS chips for personalized healthcare monitoring,demonstrating their effectiveness in target sampling and detection.Importantly,we provide a comprehensive overview of potential applications of flexible SERS chips in personalized healthcare,address current challenges,and propose future development directions.We also explore the future development of miniaturized Raman devices to broaden their applications in personalized healthcare monitoring.Additionally,we underscore the important role of AI in enhancing data processing and analysis.Our aim is to offer a thorough guide on integrating SERS into personalized healthcare monitoring,promising a new era of health management.
