With the implementation of General Senior High School Mathematics Curriculum Standards(2017 Edition,Revised in 2020),probability and statistics,as important carriers of the core mathematical competencies“mathematical...With the implementation of General Senior High School Mathematics Curriculum Standards(2017 Edition,Revised in 2020),probability and statistics,as important carriers of the core mathematical competencies“mathematical modeling”and“data analysis,”have increasingly highlighted their educational value.By summarizing the historical evolution of probability and statistics thinking and combining with teaching practice cases,this study explores its unique role in cultivating students’core mathematical competencies.The research proposes a project-based teaching strategy relying on real scenarios and empowered by technology.Through cases,it demonstrates how to use modern educational technology to realize the whole-process exploration of data collection,model construction,and conclusion verification,so as to promote the transformation of middle school probability and statistics teaching from knowledge imparting to competency development,and provide a practical reference for curriculum reform.展开更多
Declaration of Competing Interest statements is updated in the published version of the following articles that appeared in issues of Resources Chemicals and Materials.The appropriate updated Declaration of Competing ...Declaration of Competing Interest statements is updated in the published version of the following articles that appeared in issues of Resources Chemicals and Materials.The appropriate updated Declaration of Competing Interest state-ments,provided by the Authors,are included below.展开更多
The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration Compe...The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration Competing Interest statements,provided by authors,are included below.展开更多
The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration Compe...The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration Competing Interest statements,provided by authors,are included below.展开更多
The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration of Co...The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration of Competing Interest statements,provided by authors,are included below.展开更多
The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration of Co...The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration of Competing Interest statements,provided by authors,are included below.展开更多
The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration Compe...The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration Competing Interest statements,provided by authors,are included below.展开更多
Electrochemical carbon dioxide reduction reaction(CO_(2)RR)converts CO_(2) into valuable chemicals by consuming renewable electricity at mild conditions,making it a promising approach to achieving carbon neutrality.Ho...Electrochemical carbon dioxide reduction reaction(CO_(2)RR)converts CO_(2) into valuable chemicals by consuming renewable electricity at mild conditions,making it a promising approach to achieving carbon neutrality.However,the reaction of CO_(2) with hydroxide ions to form carbonates leads to low carbon utilization and energy efficiency in near-neutral or alkaline CO_(2)RR.The high concentration of protons in acidic media can effectively mitigate carbonate formation and deposition,thereby significantly minimizing carbon loss and energy consumption.Unfortunately,hydrogen evolution reaction(HER)is more kinetically favorable than CO_(2)RR in acidic media.Herein,we comprehensively overview recent progress in acidic CO_(2)RR and propose two strategies derived from the competing reaction pathways of HER and CO_(2)RR:one focuses on regulating the H+mass transport,while the other aims to modulate the intrinsic kinetic activity of CO_(2)RR.The two strategies are designed to compete for the limited active sites on the catalyst surface,inhibit side reactions,and enhance the activity and selectivity of CO_(2)RR.The representative approaches include modulating the interface electric field,constructing a local alkaline environment,and regulating competing adsorption sites.Finally,we also review the technical challenges and future perspectives of acidic CO_(2)RR coupled with membrane electrode assemblies(MEAs).展开更多
Objectives:Glioblastoma is a prevalent malignant brain tumor,and the actions of the long non-coding RNA HOXA10-AS in its invasion and migration remain unclear.Here,the function of HOXA10-AS in glioblastoma cell invasi...Objectives:Glioblastoma is a prevalent malignant brain tumor,and the actions of the long non-coding RNA HOXA10-AS in its invasion and migration remain unclear.Here,the function of HOXA10-AS in glioblastoma cell invasion and migration and associated mechanisms were investigated.Methods:HOXA10-AS was knocked down in glioblastoma cells,and Transwell and wound healing assays were conducted to elucidate its impacts on cell invasion and migration.Western blotting and quantitative reverse transcription polymerase chain reaction(qRTPCR)assessed HOXA10-AS’s impact on the epithelial-mesenchymal transition(EMT).Microarray analysis identified differentially expressed genes,complemented by bioinformatics approaches to explore potentialmolecular participants and pathways.Rescue experiments validated our findings.Results:HOXA10-AS knockdown significantly inhibits glioblastoma cell migration,invasion,and the EMT process.Specifically,HOXA10-AS siRNA transfection significantly reduced the migratory capacity of A172 cells by 50.5%and U251 cells by 61.4%,as well as their invasive capacities by 33.8%and 58.5%,respectively(all p<0.05).HOXA10-AS acts as anmiR-99a-3p sponge,and pathway analysis identified processes linked to tumorigenesis andmetastasis,alongwith nine hub genes.HOXA10-AS upregulates the expression of integrin subunit beta 5(ITGB5)through a competing endogenous RNAmechanism.Thereduced tumorigenic behavior of glioblastoma cells due toHOXA10-AS knockdown can be rescued by ITGB5 overexpression ormiR-99a-3p inhibitor.Conclusion:These results indicate thatHOXA10-AS promotes tumorigenic behavior in glioblastoma cells by regulating the EMT-like process and functioning as an miR-99a-3p sponge to modulate ITGB5 levels,providing insights into glioblastoma development and potential therapeutic targets.展开更多
Middle censoring is an important censoring scheme,in which the actual failure data of an observation becomes unobservable if it falls into a random interval. This paper considers the statistical analysis of the depend...Middle censoring is an important censoring scheme,in which the actual failure data of an observation becomes unobservable if it falls into a random interval. This paper considers the statistical analysis of the dependent competing risks model by using the Marshall-Olkin bivariate Weibull(MOBW) distribution.The maximum likelihood estimations(MLEs), midpoint approximation(MPA) estimations and approximate confidence intervals(ACIs) of the unknown parameters are obtained. In addition, the Bayes approach is also considered based on the Gamma-Dirichlet prior of the scale parameters, with the given shape parameter.The acceptance-rejection sampling method is used to obtain the Bayes estimations and construct credible intervals(CIs). Finally,two numerical examples are used to show the performance of the proposed methods.展开更多
In the new era,the impact of emerging productive forces has permeated every sector of industry.As the core production factor of these forces,data plays a pivotal role in industrial transformation and social developmen...In the new era,the impact of emerging productive forces has permeated every sector of industry.As the core production factor of these forces,data plays a pivotal role in industrial transformation and social development.Consequently,many domestic universities have introduced majors or courses related to big data.Among these,the Big Data Management and Applications major stands out for its interdisciplinary approach and emphasis on practical skills.However,as an emerging field,it has not yet accumulated a robust foundation in teaching theory and practice.Current instructional practices face issues such as unclear training objectives,inconsistent teaching methods and course content,insufficient integration of practical components,and a shortage of qualified faculty-factors that hinder both the development of the major and the overall quality of education.Taking the statistics course within the Big Data Management and Applications major as an example,this paper examines the challenges faced by statistics education in the context of emerging productive forces and proposes corresponding improvement measures.By introducing innovative teaching concepts and strategies,the teaching system for professional courses is optimized,and authentic classroom scenarios are recreated through illustrative examples.Questionnaire surveys and statistical analyses of data collected before and after the teaching reforms indicate that the curriculum changes effectively enhance instructional outcomes,promote the development of the major,and improve the quality of talent cultivation.展开更多
BACKGROUND As a non-coding RNA molecule,circular RNAs(circRNAs)have significant specificity,and existing data suggest a close relationship between them and the prognosis of patients with gastric cancer(GC).However,thi...BACKGROUND As a non-coding RNA molecule,circular RNAs(circRNAs)have significant specificity,and existing data suggest a close relationship between them and the prognosis of patients with gastric cancer(GC).However,this mechanism has no evidence yet.This article explores the functions of hsa_circRNA_102415 in the malignant behavior and potential downstream signaling of GC cells.The chosen approach is loss of signal and functional gain.AIM To investigate and analyze the relationship between hsa_circRNA_102415 and GC and explore its specific role.Results provide reference for other researchers to develop targeted treatment plans.METHODS The gene expression omnibus(GEO)database can be used to obtain the microarray dataset GSE83521.Data were analyzed using the GEO2R tool to identify differences in circRNAs between normal and GC samples.Quantitative real-time polymerase chain reaction was used to detect differentially expressed genes in GC tissue samples and adjacent cancer tissue samples.GC cells were transfected with small interfering-hsa_circRNA_104415 and plasmid DNA(pcDNA)-hsa_ircRNA_102415.Multiple detection methods,such as Transwell and cell counting kit 8,were used to evaluate cellular physiological activities,including cell invasion and proliferation.The relationship between Wnt family members 2B,microRNA(miR)-4529-5p,etc.,including argonaute 2-RNA immunoprecipitation and luciferase reporter genes was analyzed.Rescue experiments were conducted to analyze and explore the relationship between the malignant behavior of GC cells and hsa_circRNA_102415.RESULTS GEO2R analysis confirmed that hsa_circRNA_102415 had significantly higher expression levels in disease tissues.hsa_circRNA_102415 and miR-4529-5p showed a negative correlation in disease cells,suggesting that hsa_circRNA_102415 upregulated WNT2B expression in GC cells as a competing endogenous RNA for miR-4529-5p.miR-4529-5p mimic or small interfering-WNT2B reversed the effects of pcDNA-hsa_circRNA_102415 or miR-4529-5p inhibitor on cell malignant functions.CONCLUSION miR-4529-5p was used to successfully activate the potential of WNT2B,clarify the role of hsa_circRNA_102415 in GC cells,and provide reference for other researchers to develop targeted treatment plans.展开更多
This paper focuses on the ideological and political construction of the course“Probability Theory and Mathematical Statistics.”Aiming at the current situation in teaching where emphasis is placed on knowledge impart...This paper focuses on the ideological and political construction of the course“Probability Theory and Mathematical Statistics.”Aiming at the current situation in teaching where emphasis is placed on knowledge imparting while value guidance is neglected,and combined with the requirements of ideological and political education policies in the new era,this paper explores the integration path between professional courses and ideological and political education.Through literature analysis,case comparison,and empirical research,the study proposes a systematic implementation plan covering the design of teaching objectives,the reconstruction of teaching content,and the optimization of the evaluation system.The purpose is to cultivate students’sense of social responsibility and innovative awareness by excavating the ideological and political elements in mathematics.The research results provide practical reference for colleges and universities to deepen the reform of ideological and political education in courses,and promote the implementation of the fundamental task of fostering virtue through education in STEM education.展开更多
DDeeaarr EEddiittoorr,,The encoding and retrieval of emotional memories demands intricate interplay within the limbic network,where the network state is subject to significant reconfiguration by learning-induced plast...DDeeaarr EEddiittoorr,,The encoding and retrieval of emotional memories demands intricate interplay within the limbic network,where the network state is subject to significant reconfiguration by learning-induced plasticity,behavioral state,and contextual information[1].展开更多
The reliability assessment problem for products subject to degradation and random shocks is investigated. Two kinds of probabilistic models are constructed, in which the dependent competing failure process is consider...The reliability assessment problem for products subject to degradation and random shocks is investigated. Two kinds of probabilistic models are constructed, in which the dependent competing failure process is considered. First, based on the assumption of cumulative shock, the probabilistic models for hard failure and soft failure are built respectively. On this basis, the dependent competing failure model involving degradation and shock processes is established. Furthermore, the situation of the shifting-threshold is also considered, in which the hard failure threshold value decreases to a lower level after the arrival of a certain number of shocks. A case study of fatigue crack growth is given to illustrate the proposed models. Numerical results show that shock has a significant effect on the failure process; meanwhile, the effect will be magnified when the value of the hard threshold shifts to a lower level.展开更多
Variation of reservoir physical properties can cause changes in its elastic parameters. However, this is not a simple linear relation. Furthermore, the lack of observations, data overlap, noise interference, and ideal...Variation of reservoir physical properties can cause changes in its elastic parameters. However, this is not a simple linear relation. Furthermore, the lack of observations, data overlap, noise interference, and idealized models increases the uncertainties of the inversion result. Thus, we propose an inversion method that is different from traditional statistical rock physics modeling. First, we use deterministic and stochastic rock physics models considering the uncertainties of elastic parameters obtained by prestack seismic inversion and introduce weighting coefficients to establish a weighted statistical relation between reservoir and elastic parameters. Second, based on the weighted statistical relation, we use Markov chain Monte Carlo simulations to generate the random joint distribution space of reservoir and elastic parameters that serves as a sample solution space of an objective function. Finally, we propose a fast solution criterion to maximize the posterior probability density and obtain reservoir parameters. The method has high efficiency and application potential.展开更多
Considering the dependence and competitive relation-ship between traumatic failure and degradation,the reliability assessment of products based on competing failure analysis is studied.The hazard rate of traumatic fai...Considering the dependence and competitive relation-ship between traumatic failure and degradation,the reliability assessment of products based on competing failure analysis is studied.The hazard rate of traumatic failure is regarded as a Weibull distribution of the degradation performance,and the Wiener process is used to describe the degradation process.The parameters are estimated with the maximum likelihood estimation(MLE)method.A reliability model based on competing failure analysis is proposed.A case study of the GaAs lasers is given to validate the effectiveness of the model and its solving method.The results indicate that if only the degradation failure is considered,the estimated result will be comparably optimistic.Meanwhile,the correlation between the degradation and traumatic failure has a great influence on the accuracy of reliability assessment.展开更多
Ocean waves are the core environmental elements affecting the movements and structure design of ships. Statistical analysis of wave parameters is the basis for the establishment of long-term ship environmental adaptab...Ocean waves are the core environmental elements affecting the movements and structure design of ships. Statistical analysis of wave parameters is the basis for the establishment of long-term ship environmental adaptability prediction model. The observations from coastal stations, buoys, altimeters and volunteer ships that cover from 1993 to 2011 were interpolated into miller Ion-lat grids by using bilinear method and the analytical fields of ocean waves were given. By using optimal interpolation, the analysis wave fields were assimilated into the WAVEWATCH III (WW3) simulation results. From the assimilated results, the wave rose statistics, the wave height of muitiyear return period and the extreme 2-D wave spectrum are related to the ship seakeeping were calculated. Finally, the wave statistics in China offshore were analyzed in detail.展开更多
Estimation of the bivariate survival function under the competing risks caseis considered.We give an explicit formula for the estimator from a decomposition of thebivariate survival function based on competing risks,w...Estimation of the bivariate survival function under the competing risks caseis considered.We give an explicit formula for the estimator from a decomposition of thebivariate survival function based on competing risks,which is almost sure consistent.展开更多
基金2021 Annual Research Project of Yili Normal University(2021YSBS012)。
文摘With the implementation of General Senior High School Mathematics Curriculum Standards(2017 Edition,Revised in 2020),probability and statistics,as important carriers of the core mathematical competencies“mathematical modeling”and“data analysis,”have increasingly highlighted their educational value.By summarizing the historical evolution of probability and statistics thinking and combining with teaching practice cases,this study explores its unique role in cultivating students’core mathematical competencies.The research proposes a project-based teaching strategy relying on real scenarios and empowered by technology.Through cases,it demonstrates how to use modern educational technology to realize the whole-process exploration of data collection,model construction,and conclusion verification,so as to promote the transformation of middle school probability and statistics teaching from knowledge imparting to competency development,and provide a practical reference for curriculum reform.
文摘Declaration of Competing Interest statements is updated in the published version of the following articles that appeared in issues of Resources Chemicals and Materials.The appropriate updated Declaration of Competing Interest state-ments,provided by the Authors,are included below.
文摘The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration Competing Interest statements,provided by authors,are included below.
文摘The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration Competing Interest statements,provided by authors,are included below.
文摘The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration of Competing Interest statements,provided by authors,are included below.
文摘The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration of Competing Interest statements,provided by authors,are included below.
文摘The Declaration of Competing Interest statements were not included in the published version of the following articles that appeared in previous issues of Water Science and Engineering.The appropriate Declaration Competing Interest statements,provided by authors,are included below.
基金supported by the National Natural Science Foundation of China(52301259 and 22208019)the Research Fund Program for Young Scholars of Beijing Institute of Technology。
文摘Electrochemical carbon dioxide reduction reaction(CO_(2)RR)converts CO_(2) into valuable chemicals by consuming renewable electricity at mild conditions,making it a promising approach to achieving carbon neutrality.However,the reaction of CO_(2) with hydroxide ions to form carbonates leads to low carbon utilization and energy efficiency in near-neutral or alkaline CO_(2)RR.The high concentration of protons in acidic media can effectively mitigate carbonate formation and deposition,thereby significantly minimizing carbon loss and energy consumption.Unfortunately,hydrogen evolution reaction(HER)is more kinetically favorable than CO_(2)RR in acidic media.Herein,we comprehensively overview recent progress in acidic CO_(2)RR and propose two strategies derived from the competing reaction pathways of HER and CO_(2)RR:one focuses on regulating the H+mass transport,while the other aims to modulate the intrinsic kinetic activity of CO_(2)RR.The two strategies are designed to compete for the limited active sites on the catalyst surface,inhibit side reactions,and enhance the activity and selectivity of CO_(2)RR.The representative approaches include modulating the interface electric field,constructing a local alkaline environment,and regulating competing adsorption sites.Finally,we also review the technical challenges and future perspectives of acidic CO_(2)RR coupled with membrane electrode assemblies(MEAs).
基金supported by the National Natural Science Foundation of China(No.82001243).
文摘Objectives:Glioblastoma is a prevalent malignant brain tumor,and the actions of the long non-coding RNA HOXA10-AS in its invasion and migration remain unclear.Here,the function of HOXA10-AS in glioblastoma cell invasion and migration and associated mechanisms were investigated.Methods:HOXA10-AS was knocked down in glioblastoma cells,and Transwell and wound healing assays were conducted to elucidate its impacts on cell invasion and migration.Western blotting and quantitative reverse transcription polymerase chain reaction(qRTPCR)assessed HOXA10-AS’s impact on the epithelial-mesenchymal transition(EMT).Microarray analysis identified differentially expressed genes,complemented by bioinformatics approaches to explore potentialmolecular participants and pathways.Rescue experiments validated our findings.Results:HOXA10-AS knockdown significantly inhibits glioblastoma cell migration,invasion,and the EMT process.Specifically,HOXA10-AS siRNA transfection significantly reduced the migratory capacity of A172 cells by 50.5%and U251 cells by 61.4%,as well as their invasive capacities by 33.8%and 58.5%,respectively(all p<0.05).HOXA10-AS acts as anmiR-99a-3p sponge,and pathway analysis identified processes linked to tumorigenesis andmetastasis,alongwith nine hub genes.HOXA10-AS upregulates the expression of integrin subunit beta 5(ITGB5)through a competing endogenous RNAmechanism.Thereduced tumorigenic behavior of glioblastoma cells due toHOXA10-AS knockdown can be rescued by ITGB5 overexpression ormiR-99a-3p inhibitor.Conclusion:These results indicate thatHOXA10-AS promotes tumorigenic behavior in glioblastoma cells by regulating the EMT-like process and functioning as an miR-99a-3p sponge to modulate ITGB5 levels,providing insights into glioblastoma development and potential therapeutic targets.
基金supported by the National Natural Science Foundation of China(71571144 71401134)the Program of International Cooperation and Exchanges in Science and Technology Funded by Shaanxi Province(2016KW-033)
文摘Middle censoring is an important censoring scheme,in which the actual failure data of an observation becomes unobservable if it falls into a random interval. This paper considers the statistical analysis of the dependent competing risks model by using the Marshall-Olkin bivariate Weibull(MOBW) distribution.The maximum likelihood estimations(MLEs), midpoint approximation(MPA) estimations and approximate confidence intervals(ACIs) of the unknown parameters are obtained. In addition, the Bayes approach is also considered based on the Gamma-Dirichlet prior of the scale parameters, with the given shape parameter.The acceptance-rejection sampling method is used to obtain the Bayes estimations and construct credible intervals(CIs). Finally,two numerical examples are used to show the performance of the proposed methods.
文摘In the new era,the impact of emerging productive forces has permeated every sector of industry.As the core production factor of these forces,data plays a pivotal role in industrial transformation and social development.Consequently,many domestic universities have introduced majors or courses related to big data.Among these,the Big Data Management and Applications major stands out for its interdisciplinary approach and emphasis on practical skills.However,as an emerging field,it has not yet accumulated a robust foundation in teaching theory and practice.Current instructional practices face issues such as unclear training objectives,inconsistent teaching methods and course content,insufficient integration of practical components,and a shortage of qualified faculty-factors that hinder both the development of the major and the overall quality of education.Taking the statistics course within the Big Data Management and Applications major as an example,this paper examines the challenges faced by statistics education in the context of emerging productive forces and proposes corresponding improvement measures.By introducing innovative teaching concepts and strategies,the teaching system for professional courses is optimized,and authentic classroom scenarios are recreated through illustrative examples.Questionnaire surveys and statistical analyses of data collected before and after the teaching reforms indicate that the curriculum changes effectively enhance instructional outcomes,promote the development of the major,and improve the quality of talent cultivation.
文摘BACKGROUND As a non-coding RNA molecule,circular RNAs(circRNAs)have significant specificity,and existing data suggest a close relationship between them and the prognosis of patients with gastric cancer(GC).However,this mechanism has no evidence yet.This article explores the functions of hsa_circRNA_102415 in the malignant behavior and potential downstream signaling of GC cells.The chosen approach is loss of signal and functional gain.AIM To investigate and analyze the relationship between hsa_circRNA_102415 and GC and explore its specific role.Results provide reference for other researchers to develop targeted treatment plans.METHODS The gene expression omnibus(GEO)database can be used to obtain the microarray dataset GSE83521.Data were analyzed using the GEO2R tool to identify differences in circRNAs between normal and GC samples.Quantitative real-time polymerase chain reaction was used to detect differentially expressed genes in GC tissue samples and adjacent cancer tissue samples.GC cells were transfected with small interfering-hsa_circRNA_104415 and plasmid DNA(pcDNA)-hsa_ircRNA_102415.Multiple detection methods,such as Transwell and cell counting kit 8,were used to evaluate cellular physiological activities,including cell invasion and proliferation.The relationship between Wnt family members 2B,microRNA(miR)-4529-5p,etc.,including argonaute 2-RNA immunoprecipitation and luciferase reporter genes was analyzed.Rescue experiments were conducted to analyze and explore the relationship between the malignant behavior of GC cells and hsa_circRNA_102415.RESULTS GEO2R analysis confirmed that hsa_circRNA_102415 had significantly higher expression levels in disease tissues.hsa_circRNA_102415 and miR-4529-5p showed a negative correlation in disease cells,suggesting that hsa_circRNA_102415 upregulated WNT2B expression in GC cells as a competing endogenous RNA for miR-4529-5p.miR-4529-5p mimic or small interfering-WNT2B reversed the effects of pcDNA-hsa_circRNA_102415 or miR-4529-5p inhibitor on cell malignant functions.CONCLUSION miR-4529-5p was used to successfully activate the potential of WNT2B,clarify the role of hsa_circRNA_102415 in GC cells,and provide reference for other researchers to develop targeted treatment plans.
基金Shaanxi Provincial 14th Five-Year Plan for Educational Science Research(SGH24Q481)。
文摘This paper focuses on the ideological and political construction of the course“Probability Theory and Mathematical Statistics.”Aiming at the current situation in teaching where emphasis is placed on knowledge imparting while value guidance is neglected,and combined with the requirements of ideological and political education policies in the new era,this paper explores the integration path between professional courses and ideological and political education.Through literature analysis,case comparison,and empirical research,the study proposes a systematic implementation plan covering the design of teaching objectives,the reconstruction of teaching content,and the optimization of the evaluation system.The purpose is to cultivate students’sense of social responsibility and innovative awareness by excavating the ideological and political elements in mathematics.The research results provide practical reference for colleges and universities to deepen the reform of ideological and political education in courses,and promote the implementation of the fundamental task of fostering virtue through education in STEM education.
基金supported by the National Natural Science Foundation of China(T2394531)the National Key R&D Program of China(2024YFF1206500)+1 种基金the Shanghai Municipal Science and Technology Major Project(2018SHZDZX01)ZJ Lab,and the Shanghai Center for Brain Science and Brain-Inspired Technology,China.
文摘DDeeaarr EEddiittoorr,,The encoding and retrieval of emotional memories demands intricate interplay within the limbic network,where the network state is subject to significant reconfiguration by learning-induced plasticity,behavioral state,and contextual information[1].
基金The National Natural Science Foundation of China(No.50405021)Graduate Training Innovative Projects Foundation of Jiangsu Province(No.CXLX12_0081)
文摘The reliability assessment problem for products subject to degradation and random shocks is investigated. Two kinds of probabilistic models are constructed, in which the dependent competing failure process is considered. First, based on the assumption of cumulative shock, the probabilistic models for hard failure and soft failure are built respectively. On this basis, the dependent competing failure model involving degradation and shock processes is established. Furthermore, the situation of the shifting-threshold is also considered, in which the hard failure threshold value decreases to a lower level after the arrival of a certain number of shocks. A case study of fatigue crack growth is given to illustrate the proposed models. Numerical results show that shock has a significant effect on the failure process; meanwhile, the effect will be magnified when the value of the hard threshold shifts to a lower level.
基金supported by the National Science and Technology Major Project(No.2011 ZX05007-006)the 973 Program of China(No.2013CB228604)the Major Project of Petrochina(No.2014B-0610)
文摘Variation of reservoir physical properties can cause changes in its elastic parameters. However, this is not a simple linear relation. Furthermore, the lack of observations, data overlap, noise interference, and idealized models increases the uncertainties of the inversion result. Thus, we propose an inversion method that is different from traditional statistical rock physics modeling. First, we use deterministic and stochastic rock physics models considering the uncertainties of elastic parameters obtained by prestack seismic inversion and introduce weighting coefficients to establish a weighted statistical relation between reservoir and elastic parameters. Second, based on the weighted statistical relation, we use Markov chain Monte Carlo simulations to generate the random joint distribution space of reservoir and elastic parameters that serves as a sample solution space of an objective function. Finally, we propose a fast solution criterion to maximize the posterior probability density and obtain reservoir parameters. The method has high efficiency and application potential.
基金The National Natural Science Foundation of China(No.50405021)
文摘Considering the dependence and competitive relation-ship between traumatic failure and degradation,the reliability assessment of products based on competing failure analysis is studied.The hazard rate of traumatic failure is regarded as a Weibull distribution of the degradation performance,and the Wiener process is used to describe the degradation process.The parameters are estimated with the maximum likelihood estimation(MLE)method.A reliability model based on competing failure analysis is proposed.A case study of the GaAs lasers is given to validate the effectiveness of the model and its solving method.The results indicate that if only the degradation failure is considered,the estimated result will be comparably optimistic.Meanwhile,the correlation between the degradation and traumatic failure has a great influence on the accuracy of reliability assessment.
基金supports from National Natural Science Foundation of China (No. 41406032 and No. 41376014)Open Fund of State Key Laboratory of Satellite Ocean Environment Dynamics (No. SOED1305)
文摘Ocean waves are the core environmental elements affecting the movements and structure design of ships. Statistical analysis of wave parameters is the basis for the establishment of long-term ship environmental adaptability prediction model. The observations from coastal stations, buoys, altimeters and volunteer ships that cover from 1993 to 2011 were interpolated into miller Ion-lat grids by using bilinear method and the analytical fields of ocean waves were given. By using optimal interpolation, the analysis wave fields were assimilated into the WAVEWATCH III (WW3) simulation results. From the assimilated results, the wave rose statistics, the wave height of muitiyear return period and the extreme 2-D wave spectrum are related to the ship seakeeping were calculated. Finally, the wave statistics in China offshore were analyzed in detail.
文摘Estimation of the bivariate survival function under the competing risks caseis considered.We give an explicit formula for the estimator from a decomposition of thebivariate survival function based on competing risks,which is almost sure consistent.