随着先进工艺和技术的不断进步,要想保证数据在高速传输中的正确性,均衡器需要有更高的补偿和更低的功耗,才能实现高效通信。基于12 nm互补金属氧化物半导体工艺,设计了一种高增益、低功耗的自适应连续时间线性均衡器(continuous time l...随着先进工艺和技术的不断进步,要想保证数据在高速传输中的正确性,均衡器需要有更高的补偿和更低的功耗,才能实现高效通信。基于12 nm互补金属氧化物半导体工艺,设计了一种高增益、低功耗的自适应连续时间线性均衡器(continuous time linear equalizer,CTLE),该均衡器采用2级级联结构来补偿信道衰减,并提高接收信号的质量。此外,自适应模块通过采用符号-符号最小均方误差(sign-sign least mean square,SS-LMS)算法,使抽头系数加快了收敛速度。仿真结果表明,当传输速率为16 Gbit/s时,均衡器可以补偿-15.53 dB的半波特率通道衰减,均衡器系数在16×10^(4)个单元间隔数据内收敛,并且收敛之后接收误码率低于10^(-12)。展开更多
Synovial sarcoma is a high-grade soft tissue malignancy characterized by a unique fusion gene known as SS18-SSX.The SS18-SSX fusion protein acts as an oncogenic driver of synovial sarcoma,and it has thus been commonly...Synovial sarcoma is a high-grade soft tissue malignancy characterized by a unique fusion gene known as SS18-SSX.The SS18-SSX fusion protein acts as an oncogenic driver of synovial sarcoma,and it has thus been commonly accepted that disruption of SS18-SSX function represents a therapeutic means of treating synovial sarcoma,but emerging evidence suggests that upon depletion of SS18-SSX,an anti-apoptotic signal surprisingly arises to protect synovial sarcoma cell survival.In this article,we discuss the controversial roles of SS18-SSX’s transcriptional activity in synovial sarcoma biology and outline a synergistic strategy for overcoming the resistance of synovial sarcoma cells to SS18-SSX targeted therapeutics.展开更多
The dissolution behaviors of corrosion products on 316LN stainless steel(SS)in simulated shutdown acid-reducing water chemistry were investigated.The outer Fe-and Ni-rich corrosion products formed in borated and lithi...The dissolution behaviors of corrosion products on 316LN stainless steel(SS)in simulated shutdown acid-reducing water chemistry were investigated.The outer Fe-and Ni-rich corrosion products formed in borated and lithiated high-temperature water at 300℃ dissolved under the simulated shutdown acid-reducing water chemistry.NiFe_(2)O_(4)began to dissolve at the initial stage of boration,but the dissolution of Fe3O4 mainly occurred at the low-temperature stage in shutdown acid-reducing phase.Low pH value and low-temperature conditions are conducive to the dissolution of the outer Fe-rich oxides.The potential-pH(E-pH)diagrams and solubility curves of spinel oxides at different temperatures were calculated.The possible dissolution mechanism of corrosion products was discussed.展开更多
文摘随着先进工艺和技术的不断进步,要想保证数据在高速传输中的正确性,均衡器需要有更高的补偿和更低的功耗,才能实现高效通信。基于12 nm互补金属氧化物半导体工艺,设计了一种高增益、低功耗的自适应连续时间线性均衡器(continuous time linear equalizer,CTLE),该均衡器采用2级级联结构来补偿信道衰减,并提高接收信号的质量。此外,自适应模块通过采用符号-符号最小均方误差(sign-sign least mean square,SS-LMS)算法,使抽头系数加快了收敛速度。仿真结果表明,当传输速率为16 Gbit/s时,均衡器可以补偿-15.53 dB的半波特率通道衰减,均衡器系数在16×10^(4)个单元间隔数据内收敛,并且收敛之后接收误码率低于10^(-12)。
文摘Synovial sarcoma is a high-grade soft tissue malignancy characterized by a unique fusion gene known as SS18-SSX.The SS18-SSX fusion protein acts as an oncogenic driver of synovial sarcoma,and it has thus been commonly accepted that disruption of SS18-SSX function represents a therapeutic means of treating synovial sarcoma,but emerging evidence suggests that upon depletion of SS18-SSX,an anti-apoptotic signal surprisingly arises to protect synovial sarcoma cell survival.In this article,we discuss the controversial roles of SS18-SSX’s transcriptional activity in synovial sarcoma biology and outline a synergistic strategy for overcoming the resistance of synovial sarcoma cells to SS18-SSX targeted therapeutics.
基金supported by the National Natural Science Foundation of China(Nos.52171085,52371083)the Natural Science Foundation of Liaoning Province(No.2024-MSBA-76)+2 种基金the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDA0410000)the Xingliao Talent Plan of Liaoning Province(No.XLYC2202025)the CNNC Science Fund for Talented Young Scholars.
文摘The dissolution behaviors of corrosion products on 316LN stainless steel(SS)in simulated shutdown acid-reducing water chemistry were investigated.The outer Fe-and Ni-rich corrosion products formed in borated and lithiated high-temperature water at 300℃ dissolved under the simulated shutdown acid-reducing water chemistry.NiFe_(2)O_(4)began to dissolve at the initial stage of boration,but the dissolution of Fe3O4 mainly occurred at the low-temperature stage in shutdown acid-reducing phase.Low pH value and low-temperature conditions are conducive to the dissolution of the outer Fe-rich oxides.The potential-pH(E-pH)diagrams and solubility curves of spinel oxides at different temperatures were calculated.The possible dissolution mechanism of corrosion products was discussed.
