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Quality related fault detection based on dynamic-inner convolutional autoencoder and partial least squares and its application to ironmaking process
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作者 Ping Wu Yuxuan Ni +4 位作者 Huaimin Wang Xuguang Hu Zhenquan Wu Jian Jiang Yaowu Hu 《Chinese Journal of Chemical Engineering》 2026年第1期267-276,共10页
Partial least squares (PLS) model maximizes the covariance between process variables and quality variables,making it widely used in quality-related fault detection.However,traditional PLS methods focus primarily on li... Partial least squares (PLS) model maximizes the covariance between process variables and quality variables,making it widely used in quality-related fault detection.However,traditional PLS methods focus primarily on linear processes,leading to poor performance in dynamic nonlinear processes.In this paper,a novel quality-related fault detection method,named DiCAE-PLS,is developed by combining dynamic-inner convolutional autoencoder with PLS.In the proposed DiCAE-PLS method,latent features are first extracted through dynamic-inner convolutional autoencoder (DiCAE) to capture process dynamics and nonlinearity from process variables.Then,a PLS model is established to build the relationship between the extracted latent features and the final product quality.To detect quality-related faults,Hotelling's T^(2) statistic is employed.The developed quality-related fault detection is applied to the widely used industrial benchmark of the Tennessee. 展开更多
关键词 Partial least squares Dynamic-inner convolutional autoencoder Quality-related fault detection Neural networks Safety Dynamic modeling
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Prediction of total nitrogen in water based on UV spectroscopy and Bayesian optimized least squares support vector machine
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作者 ZHENG Peichao YANG Qin +3 位作者 LI Chenglin YIN Xukun WANG Jinmei GUO Lianbo 《Optoelectronics Letters》 2025年第11期698-704,共7页
The total nitrogen(TN)is a major factor contributing to eutrophication and is a crucial parameter in assessing surface water quality.Accurate and rapid methods are crucial for determining the TN content in water.Herei... The total nitrogen(TN)is a major factor contributing to eutrophication and is a crucial parameter in assessing surface water quality.Accurate and rapid methods are crucial for determining the TN content in water.Herein,a fast,highly sensitive,and pollution-free approach is proposed,which combines ultraviolet(UV)absorption spectroscopy with Bayesian optimized least squares support vector machine(LSSVM)for detecting TN content in water.Water samples collected from sampling points near the Yangtze River basin in Chongqing of China were analyzed using national standard methods to measure TN content as reference values.The prediction of TN content in water was achieved by integrating the UV absorption spectra of water samples with LSSVM.To make the model quickly and accurately select the optimal parameters to improve the accuracy of the prediction model,the Bayesian optimization(BO)algorithm was used to optimize the parameters of the LSSVM.Results show that the prediction model performs well in predicting TN concentration,with a high coefficient of prediction determination(R^(2)=0.9413)and a low root mean square error of prediction(RMSE=0.0779 mg/L).Comparative analysis with previous studies indicates that the model used in this paper achieves lower prediction errors and superior predictive performance. 展开更多
关键词 Bayesian optimization EUTROPHICATION total nitrogen tn bayesian optimized least squares support vector machine lssvm least squares support vector machine assessing surface water water quality total nitrogen
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Study of the nuclear mass model by sequential least squares programming
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作者 Hang Yang Cun-Yu Chen +2 位作者 Xiao-Yu Xu Han-Kui Wang You-Bao Wang 《Nuclear Science and Techniques》 2025年第7期204-212,共9页
Nuclear mass is an important property in both nuclear and astrophysics.In this study,we explore an improved mass model that incorporates a higher-order term of symmetry energy using algorithms.The sequential least squ... Nuclear mass is an important property in both nuclear and astrophysics.In this study,we explore an improved mass model that incorporates a higher-order term of symmetry energy using algorithms.The sequential least squares programming(SLSQP)algorithm augments the precision of this multinomial mass model by reducing the error from 1.863 MeV to 1.631 MeV.These algorithms were further examined using 200 sample mass formulae derived from theδE term of the E_(isospin) mass model.The SLSQP method exhibited superior performance compared to the other algorithms in terms of errors and convergence speed.This algorithm is advantageous for handling large-scale multiparameter optimization tasks in nuclear physics. 展开更多
关键词 Nuclear mass model Binding energy Magic nuclei Sequential least squares algorithm
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Non-negative least squares variance component estimation of mixed additive and multiplicative random error model
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作者 Hao Xiao Leyang Wang 《Geodesy and Geodynamics》 2025年第5期617-623,共7页
In the variance component estimation(VCE)of geodetic data,the problem of negative VCE is likely to occur.In the ordinary additive error model,there have been related studies to solve the problem of negative variance c... In the variance component estimation(VCE)of geodetic data,the problem of negative VCE is likely to occur.In the ordinary additive error model,there have been related studies to solve the problem of negative variance components.However,there is still no related research in the mixed additive and multiplicative random error model(MAMREM).Based on the MAMREM,this paper applies the nonnegative least squares variance component estimation(NNLS-VCE)algorithm to this model.The correlation formula and iterative algorithm of NNLS-VCE for MAMREM are derived.The problem of negative variance in VCE for MAMREM is solved.This paper uses the digital simulation example and the Digital Terrain Mode(DTM)to prove the proposed algorithm's validity.The experimental results demonstrated that the proposed algorithm can effectively correct the VCE in MAMREM when there is a negative VCE. 展开更多
关键词 Mixed additive and multiplicative random error model Stochastic model Non-negative least squares variance component estimation
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Application of Least Squares Support Vector Machine for Regression to Reliability Analysis 被引量:22
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作者 郭秩维 白广忱 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2009年第2期160-166,共7页
In order to deal with the issue of huge computational cost very well in direct numerical simulation, the traditional response surface method (RSM) as a classical regression algorithm is used to approximate a functiona... In order to deal with the issue of huge computational cost very well in direct numerical simulation, the traditional response surface method (RSM) as a classical regression algorithm is used to approximate a functional relationship between the state variable and basic variables in reliability design. The algorithm has treated successfully some problems of implicit performance function in reliability analysis. However, its theoretical basis of empirical risk minimization narrows its range of applications for... 展开更多
关键词 mechanism design of spacecraft support vector machine for regression least squares support vector machine for regression Monte Carlo method RELIABILITY implicit performance function
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Quantity of plant leaf area on three major public squares in Kunming City, China 被引量:8
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作者 董燕 赵林森 赵宇翔 《Journal of Forestry Research》 SCIE CAS CSCD 2004年第4期291-294,共4页
Regressive formulae to calculate the quantity of plant leaf area for 13 species of ornamental plants were set up based on investigation data of 30 species on 3 major public squares (Dongfeng square, Shengli square and... Regressive formulae to calculate the quantity of plant leaf area for 13 species of ornamental plants were set up based on investigation data of 30 species on 3 major public squares (Dongfeng square, Shengli square and Guandu square) in Kun-ming City, China, which were applied to calculate quantities of plant leaf area of these 13 species. The quantities of plant leaf area for the other 17 ornamental plant species on these squares were directly measured, and the total quantity of plant leaf area of each studied square was obtained individually. The results showed that the quantity of plant leaf area on Shengli square with ornamental plants structure composed of arbor tree species, shrub tree species and turf grass was highest among the three squares. It is believed that the design model of multi-storied vertical structure and proper tending of plant community could not only increase the quantity of plant leaf area, but also play an important role in generating ecological and landscaping benefits. Some corresponding suggestions were put forward on the basis of comprehensive analyses on the plant leaf area quantity of the three representative squares in Kunming urban area. 展开更多
关键词 SQUARE Ornamental plants Quantity of plant leaf area Kunming
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ONLINE PARSIMONIOUS LEAST SQUARES SUPPORT VECTOR REGRESSION AND ITS APPLICATION 被引量:2
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作者 赵永平 孙健国 王健康 《Transactions of Nanjing University of Aeronautics and Astronautics》 EI 2009年第4期280-287,共8页
A simple and effective mechanism is proposed to realize the parsimoniousness of the online least squares support vector regression (LS-SVR), and the approach is called the OPLS-SVR for short. Hence, the response tim... A simple and effective mechanism is proposed to realize the parsimoniousness of the online least squares support vector regression (LS-SVR), and the approach is called the OPLS-SVR for short. Hence, the response time is curtailed. Besides, an OPLS-SVR based analytical redundancy technique is presented to cope with the sensor failure and drift problems to guarantee that the provided signals for the aeroengine controller are correct and acceptable. Experiments on the sensor failure and drift show the effectiveness and the validity of the proposed analytical redundancy. 展开更多
关键词 support vector machines SENSORS least squares analytical redundancy aeroengines
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NOVEL WEIGHTED LEAST SQUARES SUPPORT VECTOR REGRESSION FOR THRUST ESTIMATION ON PERFORMANCE DETERIORATION OF AERO-ENGINE 被引量:2
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作者 苏伟生 赵永平 孙健国 《Transactions of Nanjing University of Aeronautics and Astronautics》 EI 2012年第1期25-32,共8页
A thrust estimator with high precision and excellent real-time performance is needed to mitigate perfor- mance deterioration for future aero-engines. A weight least squares support vector regression is proposed using ... A thrust estimator with high precision and excellent real-time performance is needed to mitigate perfor- mance deterioration for future aero-engines. A weight least squares support vector regression is proposed using a novel weighting strategy. Then a thrust estimator based on the proposed regression is designed for the perfor- mance deterioration. Compared with the existing weighting strategy, the novel one not only satisfies the require- ment of precision but also enhances the real-time performance. Finally, numerical experiments demonstrate the effectiveness and feasibility of the proposed weighted least squares support vector regression for thrust estimator. Key words : intelligent engine control; least squares ; support vector machine ; performance deterioration 展开更多
关键词 intelligent engine control least squares support vector machine performance deterioration
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An Effective Multiple Model Least Squares Method in Tracking of a Maneuvering Target 被引量:3
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作者 杨位钦 贾朝晖 《Journal of Beijing Institute of Technology》 EI CAS 1995年第1期35+29-34,共7页
A polynomial model, time origin shifting model(TOSM, is used to describe the trajectory of a moving target .Based on TOSM, a recursive laeast squares(RLS) algorithm with varied forgetting factor is derived for tracki... A polynomial model, time origin shifting model(TOSM, is used to describe the trajectory of a moving target .Based on TOSM, a recursive laeast squares(RLS) algorithm with varied forgetting factor is derived for tracking of a non-maneuvering target. In order to apply this algorithm to maneuvering targets tracking ,a tracking signal is performed on-line to determine what kind of TOSm will be in effect to track a target with different dynamics. An effective multiple model least squares filtering and forecasting method dadpted to real tracking of a maneuvering target is formulated. The algorithm is computationally more effcient than Kalman filter and the percentage improvement from simulations show both of them are considerably alike to some extent. 展开更多
关键词 Kalman filters tracking/recursive least squares maneuvering target polynomial model forgetting factor
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BOOSTING SPARSE LEAST SQUARES SUPPORT VECTOR REGRESSION (BSLSSVR) AND ITS APPLICATION TO THRUST ESTIMATION 被引量:2
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作者 赵永平 孙健国 《Transactions of Nanjing University of Aeronautics and Astronautics》 EI 2008年第4期254-261,共8页
In order to realize direct thrust control instead of conventional sensors-based control for aero-engine, a thrust estimator with high accuracy is designed by using the boosting technique to improve the performance of ... In order to realize direct thrust control instead of conventional sensors-based control for aero-engine, a thrust estimator with high accuracy is designed by using the boosting technique to improve the performance of least squares support vector regression (LSSVR). There exist two distinct features compared with the conven- tional boosting technique: (1) Sampling without replacement is used to avoid numerical instability for modeling LSSVR. (2) To realize the sparseness of LSSVR and reduce the computational complexity, only a subset of the training samples is used to construct LSSVR. Thus, this boosting method for LSSVR is called the boosting sparse LSSVR (BSLSSVR). Finally, simulation results show that BSLSSVR-based thrust estimator can satisfy the requirement of direct thrust control, i.e. , maximum absolute value of relative error of thrust estimation is not more than 5‰. 展开更多
关键词 least squares support vector machines direct thrust control boosting technique
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Semi-supervised least squares support vector machine algorithm:application to offshore oil reservoir 被引量:1
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作者 罗伟平 李洪奇 石宁 《Applied Geophysics》 SCIE CSCD 2016年第2期406-415,421,共11页
At the early stages of deep-water oil exploration and development, fewer and further apart wells are drilled than in onshore oilfields. Supervised least squares support vector machine algorithms are used to predict th... At the early stages of deep-water oil exploration and development, fewer and further apart wells are drilled than in onshore oilfields. Supervised least squares support vector machine algorithms are used to predict the reservoir parameters but the prediction accuracy is low. We combined the least squares support vector machine (LSSVM) algorithm with semi-supervised learning and established a semi-supervised regression model, which we call the semi-supervised least squares support vector machine (SLSSVM) model. The iterative matrix inversion is also introduced to improve the training ability and training time of the model. We use the UCI data to test the generalization of a semi-supervised and a supervised LSSVM models. The test results suggest that the generalization performance of the LSSVM model greatly improves and with decreasing training samples the generalization performance is better. Moreover, for small-sample models, the SLSSVM method has higher precision than the semi-supervised K-nearest neighbor (SKNN) method. The new semi- supervised LSSVM algorithm was used to predict the distribution of porosity and sandstone in the Jingzhou study area. 展开更多
关键词 Semi-supervised learning least squares support vector machine seismic attributes reservoir prediction
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Expression of Indigenous Landscapes in the Design of Modern Urban Squares 被引量:1
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作者 吴国荣 郭青媛 王长富 《Journal of Landscape Research》 2010年第4期24-26,30,共4页
Modern urban square landscapes have been evolved to be with more regional and cultural features, yet the phenomenon of duplication is serious in urban square landscapes in China. In this study, the connotation of indi... Modern urban square landscapes have been evolved to be with more regional and cultural features, yet the phenomenon of duplication is serious in urban square landscapes in China. In this study, the connotation of indigenous landscape is analyzed from the perspectives of local culture, integration of Chinese and western cultures, folk cultures and modern marketing, the causes of duplicated urban square landscapes are thoroughly elaborated. In view of the deficiencies of modern urban square landscapes, it is proposed that local plants, local ornamental materials and patterns should be fully applied in square designs, and the expression of detail landscapes should be attached sufficient importance, to completely demonstrate regional features of landscapes and better apply indigenous landscapes into the design of modern urban squares. 展开更多
关键词 URBAN square MODERN landscapes INDIGENIZATION CULTURAL COGNITION Landscape planning
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Landscape Design Practices for Urban Squares 被引量:1
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作者 孟瑾 陈良 《Journal of Landscape Research》 2010年第4期38-41,共4页
Urban squares are significant nodes of urban spaces, which should be able to improve urban ecological environment and provide residents with outdoor activity spaces. The authors studied some excellent square designs i... Urban squares are significant nodes of urban spaces, which should be able to improve urban ecological environment and provide residents with outdoor activity spaces. The authors studied some excellent square designs in Inner Mongolia, China and even overseas countries, summarized the standards of "best urban squares" in vision, culture, craft, human-concerned design, science and technology, and then applied such standards in the landscape design of Central Plaza in Zhungeer Banner. Through analyzing surrounding environment and constructions, design schemes with regional and cultural features were created to provide references for designing better green square landscapes which can demonstrate local cultural context and regional cultures, are moderate in size, diversified in spatial form and closely integrated with the social life of citizens. 展开更多
关键词 URBAN SQUARE Landscape design INNER Mongolia Zhungeer BANNER
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Chaotic time series multi-step direct prediction with partial least squares regression 被引量:2
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作者 Liu Zunxiong Liu Jianhui 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2007年第3期611-615,共5页
Considering chaotic time series multi-step prediction, multi-step direct prediction model based on partial least squares (PLS) is proposed in this article, where PLS, the method for predicting a set of dependent var... Considering chaotic time series multi-step prediction, multi-step direct prediction model based on partial least squares (PLS) is proposed in this article, where PLS, the method for predicting a set of dependent variables forming a large set of predictors, is used to model the dynamic evolution between the space points and the corresponding future points. The model can eliminate error accumulation with the common single-step local model algorithm~ and refrain from the high multi-collinearity problem in the reconstructed state space with the increase of embedding dimension. Simulation predictions are done on the Mackey-Glass chaotic time series with the model. The satisfying prediction accuracy is obtained and the model efficiency verified. In the experiments, the number of extracted components in PLS is set with cross-validation procedure. 展开更多
关键词 chaotic series prediction multi-step local model partial least squares.
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A stabilized least-squares imaging condition with structure constraints
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作者 刘国昌 陈小宏 +1 位作者 宋建勇 芮振华 《Applied Geophysics》 SCIE CSCD 2012年第4期459-467,496,共10页
Conventional shot-gather migration uses a cross-correlation imaging condition proposed by Clarebout (1971), which cannot preserve imaging amplitudes. The deconvolution imaging condition can improve the imaging ampli... Conventional shot-gather migration uses a cross-correlation imaging condition proposed by Clarebout (1971), which cannot preserve imaging amplitudes. The deconvolution imaging condition can improve the imaging amplitude and compensate for illumination. However, the deconvolution imaging condition introduces instability issues. The least-squares imaging condition first computes the sum of the cross-correlation of the forward and backward wavefields over all frequencies and sources, and then divides the result by the total energy of the forward wavefield. Therefore, the least-squares imaging condition is more stable than the classic imaging condition. However, the least-squares imaging condition cannot provide accurate results in areas where the illumination is very poor and unbalanced. To stabilize the least-squares imaging condition and balance the imaging amplitude, we propose a novel imaging condition with structure constraints that is based on the least-squares imaging condition. Our novel imaging condition uses a plane wave construction that constrains the imaging result to be smooth along geological structure boundaries in the inversion frame. The proposed imaging condition improves the stability of the imaging condition and balances the imaging amplitude. The proposed condition is applied to two examples, the horizontal layered model and the Sigsbee 2A model. These tests show that, in comparison to the damped least-squares imaging condition, the stabilized least-squares imaging condition with structure constraints improves illumination stability and balance, makes events more consecutive, adjusts the amplitude of the depth layers where the illumination is poor and unbalanced, suppresses imaging artifacts, and is conducive to amplitude preserving imaging of deep layers. 展开更多
关键词 Imaging condition least squares plane wave construction operator local event slopes
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Analysis of Current Situation and Countermeasures of Plant Landscapes on Tianjin Urban Squares of China
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作者 孟瑾 陈良 +1 位作者 王月 刘志波 《Journal of Landscape Research》 2011年第11期29-31,35,共4页
Through the survey of plant landscapes on eight representative squares in Tianjin City,the paper had pointed out that plant landscapes on Tianjin squares were improper in terms of plants richness,cultivation layer and... Through the survey of plant landscapes on eight representative squares in Tianjin City,the paper had pointed out that plant landscapes on Tianjin squares were improper in terms of plants richness,cultivation layer and color change.It had suggested selecting regional characteristic tree species,applying salt-tolerant plants,emphasizing the diversity of plants species,highlighting the application of towering arbors,stressing the use of color-leaved plants,and creating abundant plant communities,so as to provide citizens with a more practical and ornamental square landscape environment through improving plant landscapes on squares in Tianjin City. 展开更多
关键词 TIANJIN City SQUARE Plant LANDSCAPE Current SITUATION COUNTERMEASURES
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Constrained least squares algorithm for channel vector estimation in 2-D RAKE receiver
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作者 王建明 赵春明 《Journal of Southeast University(English Edition)》 EI CAS 2003年第1期1-4,共4页
Based on the fact that the variation of tile direction of arrival (DOA) isslower than that of the channel fading, the steering vector of the desired signal is estimatedfirstly using a subspace decomposition method and... Based on the fact that the variation of tile direction of arrival (DOA) isslower than that of the channel fading, the steering vector of the desired signal is estimatedfirstly using a subspace decomposition method and then a constrained condition is configured.Traffic signals are further employed to estimate the channel vector based on the constrained leastsquares criterion. We use the iterative least squares with projection (ILSP) algorithm initializedby the pilot to get the estimation. The accuracy of channel estimation and symbol detection can beprogressively increased through the iteration procedure of the ILSP algorithm. Simulation resultsdemonstrate that the proposed algorithm improves the system performance effectively compared withthe conventional 2-D RAKE receiver. 展开更多
关键词 2-D RAKE receiver channel estimation subspace decomposition constrained least squares
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PSR-SQUARES:基于程序空间约简器的SQL逆向合成系统
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作者 窦全胜 张顺 +2 位作者 潘浩 王荟贤 唐焕玲 《通信学报》 EI CSCD 北大核心 2023年第11期249-259,共11页
针对SQUARES程序空间增长过快,导致程序合成效率偏低的问题,在SQUARES的基础上,增加了以深度神经网络为核心的程序空间约简器,将给定的<被查询表,查询结果>示例表示成二维张量,作为深度神经网络的输入,网络的输出是关于目标SQL语... 针对SQUARES程序空间增长过快,导致程序合成效率偏低的问题,在SQUARES的基础上,增加了以深度神经网络为核心的程序空间约简器,将给定的<被查询表,查询结果>示例表示成二维张量,作为深度神经网络的输入,网络的输出是关于目标SQL语句合成规则的相关性标记向量。约简器根据神经网络的输出结果,采用末N位淘汰策略,删除与目标SQL语句相关性弱的合成规则,以减少候选SQL语句的生成和验证,提升系统合成效率。对约简器中深度神经网络的结构设计、训练样本集的生成方法和网络训练过程进行了详细描述。同时将PSR-SQUARES与当前有代表性SQL逆向合成系统进行实验对比,实验结果表明,PSR-SQUARES的综合性能不同程度地优于其他合成系统,平均合成时间由SQUARES的251 s降低至130 s,目标程序合成成功率由80%提升至89%。 展开更多
关键词 程序合成 SQL逆向合成 squares 程序空间约简器 领域特定语言
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A stem taper equation for Eucalyptus camaldulensis in northeast Nigeria
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作者 Williams Danladi Abwage Tomiwa Victor Oluwajuwon +3 位作者 Segun Michael Adedapo Abdulaziz Adamu Patrick Corey Green Friday Nwabueze Ogana 《Journal of Forestry Research》 2026年第2期44-57,共14页
Eucalyptus(Eucalyptus camaldulensis Dehnh.)is an important exotic species in northern Nigeria commonly used for poles and timber.Sustainable management of this resource would require quantifying its volume.Stem taper ... Eucalyptus(Eucalyptus camaldulensis Dehnh.)is an important exotic species in northern Nigeria commonly used for poles and timber.Sustainable management of this resource would require quantifying its volume.Stem taper equations are one of the main and most efficient methods for estimating stem volume to any merchantable limit of a species.There is currently no taper equation for Eucalyptus species in Nigeria.Therefore,this study developed taper equations for E.camaldulensis in northern Nigeria.Data for this study were obtained from a private plantation in Jalingo Local Government Area,Taraba State,Nigeria.68 trees were felled and sectioned into 1-m bolt across the stem to a merchantable limit of 5 cm,which were used as the fitting dataset.An additional 22 trees were felled and used to validate the taper equations for stem volume estimation.Seven taper equations were initially fitted to the dataset using nonlinear least squares.The best taper equation was then refitted using a nonlinear mixed-effects approach and calibrated using diameters of one to five sections from the butt end.The taper equations were numerically integrated to obtain the stem volume,which was compared with empirical volume equations.The result shows that the Kozak(Can J For Res 27(5):619-629.10.1139/x97-011,1997)equation,which included eight parameters,provided the best fit for predicting section diameters for under and over bark.The mixed-effects taper equation(NLME-TE)explained most stem diameter variations in the fitting dataset(pseudo-R2:0.986-0.987;RMSE:0.547-0.578 cm)without substantial residual trends.The validation showed that the prediction accuracy of the integrated NLME-TE improved as the number of sectional diameter measurements increased,with at least a 35%reduction in volume estimate error.For practical implementation,two calibration sectional diameter measurements taken from the butt end per tree are recommended.This approach would reduce measurement effort and cost while improving model performance. 展开更多
关键词 Eucalyptus plantation Stem volume Nonlinear least squares Mixed-effects Response calibration
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Direct UV photolysis of cloperastine in aqueous solution:Kinetic model and degradation pathway
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作者 Marc Marín-García Rafael Gonzalez-Olmos Cristian Gómez-Canela 《Journal of Environmental Sciences》 2026年第1期670-682,共13页
The increasing production and release of synthetic organic chemicals,including pharmaceuticals,into our envi-ronment has allowed these substances to accumulate in our surface water systems.Current purification technol... The increasing production and release of synthetic organic chemicals,including pharmaceuticals,into our envi-ronment has allowed these substances to accumulate in our surface water systems.Current purification technolo-gies have been unable to eliminate these pollutants,resulting in their ongoing release into aquatic ecosystems.This study focuses on cloperastine(CPS),a cough suppressant and antihistamine medication.The environmental impact of CPS usage has become a concern,mainly due to its increased detection during the COVID-19 pandemic.CPS has been found in wastewater treatment facilities,effluents from senior living residences,river waters,and sewage sludge.However,the photosensitivity of CPS and its photodegradation profile remain largely unknown.This study investigates the photodegradation process of CPS under simulated tertiary treatment conditions using UV photolysis,a method commonly applied in some wastewater treatment plants.Several transformation prod-ucts were identified,evaluating their kinetic profiles using chemometric approaches(i.e.,curve fitting and the hard-soft multivariate curve resolution-alternating least squares(HS-MCR-ALS)algorithm)and calculating the reaction quantum yield.As a result,three different transformation products have been detected and correctly identified.In addition,a comprehensive description of the kinetic pathway involved in the photodegradation process of the CPS drug has been provided,including observed kinetic rate constants. 展开更多
关键词 Cloperastine UV photolysis UHPLC-QTOF-MS/MS Kinetic model Degradation pathway Hard-soft multivariate curve resolution-alternating least squares (HS-MCR-ALS)
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