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Vibration Spectrums of Polar Interface Optical Phonons in GaAs/AlAs Cylindrical Quantum Dots
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作者 ZHANGLi 《Communications in Theoretical Physics》 SCIE CAS CSCD 2005年第2期333-336,共4页
The dispersions of the top interface optical phonons and the side interface optical phonons in cylindrical quantum dots are solved by using the dielectric continuum model. Our calculation mainly focuses on the frequen... The dispersions of the top interface optical phonons and the side interface optical phonons in cylindrical quantum dots are solved by using the dielectric continuum model. Our calculation mainly focuses on the frequency dependence of the IO phonon modes on the wave-vector and quantum number in the cylindrical quantum dot system.Results reveal that the frequency of top interface optical phonon sensitively depends on the discrete wave-vector in z direction and the azimuthal quantum number, while that of the side interface optical phonon mode depends on the radial and azimuthal quantum numbers. These features are obviously different from those in quantum well, quantum well wire,and spherical quantum dot systems. The limited frequencies of interface optical modes for the large wave-vector or quantum number approach two certain constant values, and the math and physical reasons for this feature have been explained reasonably. 展开更多
关键词 phonon modes vibration spectrums cylindrical quantum dots
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A Note on the Prime Spectrums of Character Rings of Finite Groups
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作者 CHEN Gang FAN Yun YUAN Yua 《Wuhan University Journal of Natural Sciences》 CAS 2006年第2期339-342,共4页
Let G be a finite group with order g and S be a subring of the algebraic number field which contains the integral extension over Z generated by a g-th primitive root co of unity, and R(G) be the character ring of G.... Let G be a finite group with order g and S be a subring of the algebraic number field which contains the integral extension over Z generated by a g-th primitive root co of unity, and R(G) be the character ring of G. The prime spectrum of the commutative ring S×Z R(G) iv denoted by Spec(S×Z R(G)) and set π={p|p is a rational prime number such that p^-1 S}. We prove that when G is a regroup, a π'-group, or a finite Abelian group, the number of the connetted components of Spec( S×Z R (G) ) coincides with the number of the π-regular classes in G, 展开更多
关键词 prime spectrums connected components π-regular conjugacy classes
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An unsupervised clustering method for nuclear magnetic resonance transverse relaxation spectrums based on the Gaussian mixture model and its application 被引量:3
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作者 GE Xinmin XUE Zong’an +6 位作者 ZHOU Jun HU Falong LI Jiangtao ZHANG Hengrong WANG Shuolong NIU Shenyuan ZHAO Ji’er 《Petroleum Exploration and Development》 CSCD 2022年第2期339-348,共10页
To make the quantitative results of nuclear magnetic resonance(NMR) transverse relaxation(T;) spectrums reflect the type and pore structure of reservoir more directly, an unsupervised clustering method was developed t... To make the quantitative results of nuclear magnetic resonance(NMR) transverse relaxation(T;) spectrums reflect the type and pore structure of reservoir more directly, an unsupervised clustering method was developed to obtain the quantitative pore structure information from the NMR T;spectrums based on the Gaussian mixture model(GMM). Firstly, We conducted the principal component analysis on T;spectrums in order to reduce the dimension data and the dependence of the original variables. Secondly, the dimension-reduced data was fitted using the GMM probability density function, and the model parameters and optimal clustering numbers were obtained according to the expectation-maximization algorithm and the change of the Akaike information criterion. Finally, the T;spectrum features and pore structure types of different clustering groups were analyzed and compared with T;geometric mean and T;arithmetic mean. The effectiveness of the algorithm has been verified by numerical simulation and field NMR logging data. The research shows that the clustering results based on GMM method have good correlations with the shape and distribution of the T;spectrum, pore structure, and petroleum productivity, providing a new means for quantitative identification of pore structure, reservoir grading, and oil and gas productivity evaluation. 展开更多
关键词 NMR T2 spectrum Gaussian mixture model expectation-maximization algorithm Akaike information criterion unsupervised clustering method quantitative pore structure evaluation
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A high performance fast-Fourier-transform spectrum analyzer for measuring spin noise spectrums 被引量:1
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作者 Yu Tong Lin Wang +5 位作者 Wen-Zhe Zhang Ming-Dong Zhu Xi Qin Min Jiang Xing Rong Jiangfeng Du 《Chinese Physics B》 SCIE EI CAS CSCD 2020年第9期259-266,共8页
A high performance fast-Fourier-transform (FFT) spectrum analyzer, which is developed for measure spin noise spectrums, is presented in this paper. The analyzer is implemented with a field-programmable-gate-arrays (FP... A high performance fast-Fourier-transform (FFT) spectrum analyzer, which is developed for measure spin noise spectrums, is presented in this paper. The analyzer is implemented with a field-programmable-gate-arrays (FPGA) chip for data and command management. An analog-to-digital-convertor chip is integrated for analog signal acquisition. In order to meet the various requirements of measuring different types of spin noise spectrums, multiple operating modes are designed and realized using the reprogrammable FPGA logic resources. The FFT function is fully managed by the programmable resource inside the FPGA chip. A 1 GSa/s sampling rate and a 100 percent data coverage ratio with non-dead-time are obtained. 30534 FFT spectrums can be acquired per second, and the spectrums can be on-board accumulated and averaged. Digital filters, multi-stage reconfigurable data reconstruction modules, and frequency down conversion modules are also implemented in the FPGA to provide flexible real-time data processing capacity, thus the noise floor and signals aliasing can be suppressed effectively. An efficiency comparison between the FPGA-based FFT spectrum analyzer and the software-based FFT is demonstrated, and the high performance FFT spectrum analyzer has a significant advantage in obtaining high resolution spin noise spectrums with enhanced efficiency. 展开更多
关键词 fast Fourier transform spectrum analyzer field-programmable-gate-arrays(FPGA) spin noise spectrum
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Nonlinear response spectrums for cable-supported glass curtain walls
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作者 周华樟 武岳 祝恩淳 《Journal of Harbin Institute of Technology(New Series)》 EI CAS 2007年第6期827-832,共6页
Aiming at the seismic-resistant performance of cable-supported glass curtain walls,the methods for formulating nonlinear single degree of freedom system and calculating the nonlinear response spectrums are proposed. T... Aiming at the seismic-resistant performance of cable-supported glass curtain walls,the methods for formulating nonlinear single degree of freedom system and calculating the nonlinear response spectrums are proposed. Taking pretension effect in cables and geometrical nonlinearity into account,the nonlinear acceleration spectrums are calculated under given conditions,such as site and different seismic fortification intensities. The seismic design response spectrums are developed. During vibrating,varying period due to the influence of pretension effect in cables and geometrical nonlinearity drives the maximum period of plateau in nonlinear response spectrums to move towards the long period zone,and the maximum of seismic effect coefficient is larger than that of current seismic code. The theoretical analysis and the example demonstrate that using the nonlinear response spectrums is safe and economical. 展开更多
关键词 cable-supported structure glass curtain wall nonlinear response spectrum seismic design
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GC-MS Spectrums and Their Close Match Methyl Esters from Mushrooms of Papua New Guinea
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作者 John Kia Nema Stewart Wabo Wossa +1 位作者 Basil Marasinghe Russell Allan Barrow 《Journal of Chemistry and Chemical Engineering》 2014年第12期1093-1097,共5页
The GC-MS spectrums of a sample from Amanitaceae family and Mycenaceae family were matched with their close match GC-MS spectrums from the spectrum library. The samples from Amanitaceae family (KMsp027) and Mycenace... The GC-MS spectrums of a sample from Amanitaceae family and Mycenaceae family were matched with their close match GC-MS spectrums from the spectrum library. The samples from Amanitaceae family (KMsp027) and Mycenaceae family (KMsp039) were found to contain fatty acid methyl esters (methyl palmitate and methyl linoleate). It is proposed that the presence of methyl linoleate and methyl palmitate in the samples may show antibacterial activities if tested against different bacterial strains. 展开更多
关键词 Methyl esters GC-MS spectrum Papua New Guinea.
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Grading of Brain Tumors by Mining MRS Spectrums Using LabVIEW <br/>—Metabolite Peak Height Scanning Method
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作者 Jayalaxmi S. Gonal Vinayadatt V. Kohir 《Open Journal of Medical Imaging》 2017年第1期17-27,共11页
In this paper, we attempt to resolve the problem of grading of brain tumors as grade 2, grade 3, grade 4, using information from magnetic resonance spectroscopy (MRS) image, to assist in clinical diagnosis. This paper... In this paper, we attempt to resolve the problem of grading of brain tumors as grade 2, grade 3, grade 4, using information from magnetic resonance spectroscopy (MRS) image, to assist in clinical diagnosis. This paper proposes a novel approach to extract metabolite values represented in a graphical form in MR Spectroscopy image. Metabolites like N-acetyl aspartate (NAA), Choline (CHO) along with the metabolite ratios NAA/CHO and presence/absence of LACTATE peak play the most important role in deciding the tumor type. The proposed approach consists of several steps including preprocessing, metabolite peak height scanning and classification. Proposed system stores the metabolite values in dataset instead of storing MRS images;so reduces the image processing tasks and memory requirements. Further these metabolite values and ratios are fed to a BPN classifier. Experimental results demonstrate the effectiveness of the proposed approach in classifying the brain tumors. 展开更多
关键词 MR Spectrum METABOLITE PEAK HEIGHT Graph SCANNING Vision Assistant LABVIEW BPN Classifier
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Evaluation of eco-driving performance of electric vehicles using driving behavior-enabled graph spectrums:A naturalistic driving study in China
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作者 Hui Zhang Yiyue Luo +5 位作者 Naikan Ding Toshiyuki Yamamoto Chenming Fan Chunhui Yang Wei Xu Chaozhong Wu 《Green Energy and Intelligent Transportation》 2025年第1期76-87,共12页
Electric vehicles are widely embraced as a promising solution to reduce energy consumption and emission to achieve the Carbon Peak and Carbon Neutrality vision,especially in developing countries.Specifically,it’s vit... Electric vehicles are widely embraced as a promising solution to reduce energy consumption and emission to achieve the Carbon Peak and Carbon Neutrality vision,especially in developing countries.Specifically,it’s vital important to understand the ecological performance of electric vehicles and its association with driving behaviors under varying road and environmental conditions.However,current researches on ecological driving behavior mostly use structured data to reflect the characteristics of ecological driving behavior,and it is difficult to accurately reveal the recessive relationship between driving behavior and energy consumption.One promising and prevalent method for comprehensively and in-depth characterizing driving behaviors is“graph spectrums”,which allows for an effective and illustrative representation of complex driving behavior characteristics.This study presented an assessment method of ecological driving for electric vehicles based on the graph.Firstly,a multi-source refined data set was constructed through naturalistic driving experiments(NDE).Four typical traffic state(CCCF:congested close car-following;CSSF:constrained slow free-flow;CSCF:constrained slow carfollowing;UFFF:unconstrained fast free-flow)were classified through longitudinal acceleration data,and driving behavior graph was constructed to realize the visual representation of driving behavior.Then,the energy consumption graph was constructed using the energy loss of 100 km(EL)index.After the six drivers with the highest and lowest ecological assessment of driving behavior using the behavior graph and energy consumption graph,proposing the quantitative analysis of fifteen drivers'ecology driving behavior.The results show that:1)The graphical method can describe the individual features of a driver’s ecological driving behavior;2)Rapid acceleration of driving behavior leads to high energy consumption;3)In the comparison among the six ecodrivers and energy-intensive drivers,founding that the energy-intensive drivers accelerate and decelerate significantly more in CCCF traffic state;4)The driving behavior was more complex and unecological in CCCF traffic state;5)Fifteen drivers had lower ecological scores in start-up driving.This study proposes a method for visualizing ecology driving behavior that not only help understand the individual characteristics of ecological driving behaviors,but also offers substantial application value for the subsequent construction of Ecological driving behavior regulation models. 展开更多
关键词 Electric vehicle Eco-driving behavior Driving behavior graph spectrum Energy consumption graph spectrum Naturalistic driving study
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Light Regulation across Strawberry Growth Stages:A Comprehensive Review
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作者 Geng Zhang Xiangyu Ding +7 位作者 Zidan Wen Chao Liu Duyen T.P.Nguyen Jinxiu Song Zejin Zhang Zhiming Yan Yuanhua Wang Zhengnan Yan 《Phyton-International Journal of Experimental Botany》 2026年第2期1-21,共21页
As a pivotal environmental factor,light,comprising intensity,photoperiod,and spectrum,governs the entire life cycle of strawberries by mediating alterations in the plant’s morphological,physiological,and biochemical ... As a pivotal environmental factor,light,comprising intensity,photoperiod,and spectrum,governs the entire life cycle of strawberries by mediating alterations in the plant’s morphological,physiological,and biochemical traits.Although extensive research has been conducted on light-mediated growth regulation in horticultural crops,most reviews focus primarily on leafy and fruiting vegetables,with limited attention given to berry crops such as strawberries.Additionally,most existing reviews concentrate on one or several growth stages,failing to systematically characterize light’s effects throughout the entire growth cycle and postharvest stage.This review briefly summarizes the regulatory roles of light across key stages of strawberry growth,including seedling propagation,vegetative growth,reproductive growth,and postharvest stages.It seeks to address the knowledge gap by systematically organizing research findings across these developmental phases.The integrated analysis provides a theoretical foundation for designing stage-specific lighting strategies to improve strawberry yield and quality. 展开更多
关键词 Light intensity light spectrum STRAWBERRY seedling propagation vegetative growth reproductive growth POSTHARVEST
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Research on characterization methods for track irregularities
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作者 Lifeng Xin Lei Xu +3 位作者 Jiaxin Zhang Menglin Pei Jianfeng Mao Dangxiong Wang 《Railway Engineering Science》 2026年第1期25-39,共15页
The characterization of track irregularities is crucial in railway dynamics,as track irregularities are the primary source of internal excitation in railway systems.In this paper,three mathematical models are proposed... The characterization of track irregularities is crucial in railway dynamics,as track irregularities are the primary source of internal excitation in railway systems.In this paper,three mathematical models are proposed to characterize the track irregularities under different circumstances.The first model is a novel explicit track spectrum function,which performs better in reflecting the inherent periodic components of track irregularities than the existing track spectra.On this foundation,the second model,a parameterized track spectrum random model,is proposed to represent the vast measured track irregularities from the probabilistic perspective.Finally,the third model,an imprecise track spectrum interval model based on a neighborhood uniform sampling Bootstrap method,is presented to identify the confidential interval of the track spectra when the track irregularity data are limited.Three examples are illustrated to demonstrate the feasibility of the three track irregularity models in characterizing the track irregularities in different conditions.This research can help capture the railway deformation status and optimize track maintenance strategies. 展开更多
关键词 RAILWAY Track irregularity Power spectral density CHARACTERIZATION Random model Imprecise track spectrum
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Redundant source-wavelet amplitude influence in wave-equation migration/demigration flow and its removal
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作者 QianCheng Liu JiaLe Kang Jie Li 《Earth and Planetary Physics》 2026年第1期75-81,共7页
In wave-equation migration and demigration,the cross-correlation imaging/forwarding step implicitly injects an additional copy of the source wavelet,so that the amplitude spectrum of the wavelet is applied redundantly... In wave-equation migration and demigration,the cross-correlation imaging/forwarding step implicitly injects an additional copy of the source wavelet,so that the amplitude spectrum of the wavelet is applied redundantly(effectively imposing a wavelet-spectrum weighting,often akin to an amplitude-squared bias).This redundancy degrades structural fidelity and amplitude balance yet is frequently overlooked.We(i)formalize the mechanism by which cross-correlation duplicates the source-wavelet amplitude effect in both migration and demigration,and(ii)introduce a source-equalized operator that removes the redundancy by deconvolving(or dividing by)the wavelet amplitude spectrum in the imaging condition and its demigration counterpart,while leaving phase/kinematics intact.Using a band-limited Ricker wavelet on a two-layer model and on Marmousi,we show that,if unmanaged,the redundant wavelet spectrum broadens main lobes,introduces ringing,and suppresses vertical resolution in migrated images,and inflates spectrum mismatches between demigrated and observed data even when peak times agree.With our correction,images recover observed-data-consistent bandwidth and sharpened interfaces,and demigrated data also exhibit improved spectrum conformity and reduced amplitude misfit.The results clarify when source amplitudes matter,why cross-correlation makes them redundantly matter,and how a lightweight spectral correction restores physically meaningful amplitude behavior in wave-equation migration/demigration. 展开更多
关键词 wave-equation migration DEMIGRATION cross-correlation imaging condition source wavelet amplitude spectrum spectral deconvolution
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Super-resolution reconstruction of UAV-borne gamma-ray spectrum images based on Real-ESRGAN algorithm
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作者 Xin Wang Yuan Yuan +4 位作者 Xuan Zhao Guang-Hao Luo Qi-Qiao Wei He-Xi Wu Chao Xiong 《Nuclear Science and Techniques》 2026年第2期42-54,共13页
Unmanned aerial vehicle(UAV)-borne gamma-ray spectrum survey plays a crucial role in geological mapping,radioactive mineral exploration,and environmental monitoring.However,raw data are often compromised by flight and... Unmanned aerial vehicle(UAV)-borne gamma-ray spectrum survey plays a crucial role in geological mapping,radioactive mineral exploration,and environmental monitoring.However,raw data are often compromised by flight and instrument background noise,as well as detector resolution limitations,which affect the accuracy of geological interpretations.This study aims to explore the application of the Real-ESRGAN algorithm in the super-resolution reconstruction of UAV-borne gamma-ray spectrum images to enhance spatial resolution and the quality of geological feature visualization.We conducted super-resolution reconstruction experiments with 2×,4×and 6×magnification using the Real-ESRGAN algorithm,comparing the results with three other mainstream algorithms(SRCNN,SRGAN,FSRCNN)to verify the superiority in image quality.The experimental results indicate that Real-ESRGAN achieved a structural similarity index(SSIM)value of 0.950 at 2×magnification,significantly higher than the other algorithms,demonstrating its advantage in detail preservation.Furthermore,Real-ESRGAN effectively reduced ringing and overshoot artifacts,enhancing the clarity of geological structures and mineral deposit sites,thus providing high-quality visual information for geological exploration. 展开更多
关键词 UAV-borne gamma-ray spectrum Super-resolution reconstruction Real-ESRGAN Image processing
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Reconfigurable Intelligent Surface Aided Integrated Communication and Localization with a Single Access Point
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作者 Wang Xiyu Huang Yixuan +2 位作者 Yang Jie Han Yu Jin Shi 《China Communications》 2026年第1期218-233,共16页
Reconfigurable intelligent surfaces(RISs)not only assist communication but also help the localization of user equipment(UE).This study focuses on indoor localization of UE with a single access point(AP)and multiple RI... Reconfigurable intelligent surfaces(RISs)not only assist communication but also help the localization of user equipment(UE).This study focuses on indoor localization of UE with a single access point(AP)and multiple RISs.First,we propose a two-stage channel estimation scheme where RIS phase shifts are tuned to obtain multiple channel soundings.In the first stage,the newtonized orthogonal matching pursuit algorithm extracts the parameters of multiple paths from the received signals.Then,the LOS path and RISreflected paths are identified.In the second stage,the estimated path gains of RIS-reflected paths with different phase shifts are utilized to determine the angle of arrival(AOA)at the RIS by obtaining the angular pseudo spectrum.Consequently,by taking the AP and RISs as reference points,the linear least squares estimator can locate UE with the estimated AOAs.Simulation results show that the proposed algorithm can realize centimeter-level localization accuracy in the discussed scenarios.Moreover,the higher accuracy of pseudo spectrum,a larger number of channel soundings,and a larger number of reference points can realize higher localization accuracy of UE. 展开更多
关键词 channel estimation indoor localization linear least squares pseudo spectrum reconfigurable intelligent surface
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The measurement of the energy correlations between two^(252)Cf prompt fission neutrons
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作者 Huai-Yong Bai Hang Li +8 位作者 Hong-Jun Zhang Cheng-Guo Pang Ming Su Zhong-Hua Xiong Ji Wen Fan Gao Chen-Guang Li Xiao-Dong Wang Li-Sheng Yang 《Nuclear Science and Techniques》 2026年第4期202-215,共14页
The energy correlations of prompt fission neutrons have not yet been considered in the related coincidence and multiplication measurement techniques.To measure and verify the energy correlations,an experiment was perf... The energy correlations of prompt fission neutrons have not yet been considered in the related coincidence and multiplication measurement techniques.To measure and verify the energy correlations,an experiment was performed with a total measurement duration of approximately 1200 h.In the experiment,eight CLYC detectors and sixteen EJ309 liquid scintillation detectors were utilized,and the fission moment was tagged with the measured fissionγ-rays.The relative ratios of the energy spectra of the neutrons correlated with different energy neutrons to the^(252)Cf fission neutron energy spectra were obtained.The present results may be helpful for studying fission physics and nuclear technology applications. 展开更多
关键词 Energy correlations Prompt fission neutrons Energy spectrum Fissionγ-rays
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Octupole correlations of the K^(π)=5/2^(+)ground-state band in^(229)Th
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作者 Yuan-Yuan Wang Peng-Wei Zhao 《Chinese Physics B》 2026年第2期156-161,共6页
The octupole correlations of the K^(π)=5/2^(+)ground state and the rotational spectrum built on it in^(229)Th are studied using the microscopic relativistic density functional theory on a three-dimensional lattice sp... The octupole correlations of the K^(π)=5/2^(+)ground state and the rotational spectrum built on it in^(229)Th are studied using the microscopic relativistic density functional theory on a three-dimensional lattice space and the reflection-asymmetric triaxial particle rotor model.It is found that^(229)Th has a ground state with static axial octupole and quadrupole deformations.The occurrence of octupole correlations,driven by the octupole deformation,is analyzed through the evolution of single-particle levels around the Fermi surface.The experimental energy spectrum and the electromagnetic transition probabilities,including B(E2)and B(M1),are reasonably well reproduced. 展开更多
关键词 octupole correlation relativistic density functional theory reflection-asymmetric triaxial particle rotor model rotational spectrum
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Voltage-gated sodium channels in the nervous system:Molecular physiology to therapeutic interventions
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作者 Ni Li Lin Yan +3 位作者 Anna Peng Xuefei Fu Huan Qin Kai Yao 《Neural Regeneration Research》 2026年第6期2085-2100,共16页
Voltage-gated sodium channels are essential ionic-conductance pathways in the nervous system,which play an irreplaceable role in modulating neuronal excitability and signal transduction.This review comprehensively ana... Voltage-gated sodium channels are essential ionic-conductance pathways in the nervous system,which play an irreplaceable role in modulating neuronal excitability and signal transduction.This review comprehensively analyzes the molecular mechanisms and pathophysiological significance of voltage-gated sodium channels,with particular emphasis on elucidating the molecular-action mechanisms of the distinct subtypes of these channels,including Nav1.1,Nav1.2,and Nav1.6,across various neurological disorders such as familial hemiplegic migraine,epilepsy,autism spectrum disorder,and retinal dysfunction.This review also provides a comprehensive overview of the pathogenic mechanisms associated with voltage-gated sodium channels,and systematically clarifies the evolutionary pathway of treatment strategies from conventional to innovative approaches.It analyzes two major categories of conventional sodium channel blockers and their applications:antiepileptic drugs(such as carbamazepine,lamotrigine,and phenytoin)and antiarrhythmic drugs(such as lidocaine,flecainide,and quinidine).However,these conventional blockers show limitations because of the lack of selectivity,driving research toward more precise therapeutic directions.Additionally,this review evaluates gabapentin,cannabidiol,and calcium channel blockers with different mechanisms of action.These drugs modulate neuronal excitability from multiple perspectives,providing diverse options for symptom relief.This review also highlights advances in gene therapy for specific diseases,such as STK-001,which promotes effective splicing of the sodium channel voltage-gated type 1 alpha subunit(SCN1A)gene,and ETX101,which utilizes adeno-associated virus 9 vectors to deliver engineered transcription factors.These two agents provide targeted therapeutic solutions for Dravet syndrome.Furthermore,this review summarizes some innovative therapeutic agents in clinical trials,including PRAX-222(for SCN2A gain-offunction mutation-related epilepsy),which has received Food and Drug Administration orphan drug designation,and the selective Nav1.6 inhibitor NBI-921352(for SCN8A-related epilepsy).Collectively,this review comprehensively compares the advantages and disadvantages of conventional drugs and gene therapy and envisions future treatment strategies that integrate the strengths of both approaches,facilitating personalized precision medicine to provide more accurate and effective treatment options for patients with ion channel diseases. 展开更多
关键词 autism spectrum disorder CHANNELOPATHIES clinical trial Dravet syndrome EPILEPSY familial hemiplegic migraine gene therapy nerve regeneration neuronal regeneration renin-angiotensin system retinal degeneration
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Mitochondrial dynamics dysfunction and neurodevelopmental disorders:From pathological mechanisms to clinical translation
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作者 Ziqi Yang Yiran Luo +5 位作者 Zaiqi Yang Zheng Liu Meihua Li Xiao Wu Like Chen Wenqiang Xin 《Neural Regeneration Research》 2026年第5期1926-1946,共21页
Mitochondrial dysfunction has emerged as a critical factor in the etiology of various neurodevelopmental disorders, including autism spectrum disorders, attention-deficit/hyperactivity disorder, and Rett syndrome. Alt... Mitochondrial dysfunction has emerged as a critical factor in the etiology of various neurodevelopmental disorders, including autism spectrum disorders, attention-deficit/hyperactivity disorder, and Rett syndrome. Although these conditions differ in clinical presentation, they share fundamental pathological features that may stem from abnormal mitochondrial dynamics and impaired autophagic clearance, which contribute to redox imbalance and oxidative stress in neurons. This review aimed to elucidate the relationship between mitochondrial dynamics dysfunction and neurodevelopmental disorders. Mitochondria are highly dynamic organelles that undergo continuous fusion and fission to meet the substantial energy demands of neural cells. Dysregulation of these processes, as observed in certain neurodevelopmental disorders, causes accumulation of damaged mitochondria, exacerbating oxidative damage and impairing neuronal function. The phosphatase and tensin homolog-induced putative kinase 1/E3 ubiquitin-protein ligase pathway is crucial for mitophagy, the process of selectively removing malfunctioning mitochondria. Mutations in genes encoding mitochondrial fusion proteins have been identified in autism spectrum disorders, linking disruptions in the fusion-fission equilibrium to neurodevelopmental impairments. Additionally, animal models of Rett syndrome have shown pronounced defects in mitophagy, reinforcing the notion that mitochondrial quality control is indispensable for neuronal health. Clinical studies have highlighted the importance of mitochondrial disturbances in neurodevelopmental disorders. In autism spectrum disorders, elevated oxidative stress markers and mitochondrial DNA deletions indicate compromised mitochondrial function. Attention-deficit/hyperactivity disorder has also been associated with cognitive deficits linked to mitochondrial dysfunction and oxidative stress. Moreover, induced pluripotent stem cell models derived from patients with Rett syndrome have shown impaired mitochondrial dynamics and heightened vulnerability to oxidative injury, suggesting the role of defective mitochondrial homeostasis in these disorders. From a translational standpoint, multiple therapeutic approaches targeting mitochondrial pathways show promise. Interventions aimed at preserving normal fusion-fission cycles or enhancing mitophagy can reduce oxidative damage by limiting the accumulation of defective mitochondria. Pharmacological modulation of mitochondrial permeability and upregulation of peroxisome proliferator-activated receptor gamma coactivator 1-alpha, an essential regulator of mitochondrial biogenesis, may also ameliorate cellular energy deficits. Identifying early biomarkers of mitochondrial impairment is crucial for precision medicine, since it can help clinicians tailor interventions to individual patient profiles and improve prognoses. Furthermore, integrating mitochondria-focused strategies with established therapies, such as antioxidants or behavioral interventions, may enhance treatment efficacy and yield better clinical outcomes. Leveraging these pathways could open avenues for regenerative strategies, given the influence of mitochondria on neuronal repair and plasticity. In conclusion, this review indicates mitochondrial homeostasis as a unifying therapeutic axis within neurodevelopmental pathophysiology. Disruptions in mitochondrial dynamics and autophagic clearance converge on oxidative stress, and researchers should prioritize validating these interventions in clinical settings to advance precision medicine and enhance outcomes for individuals affected by neurodevelopmental disorders. 展开更多
关键词 autophagic clearance autism spectrum disorders cellular homeostasis fusion and fission mitochondrial dynamics MITOPHAGY neural regeneration neuronal energy metabolism neurodevelopmental disorders oxidative stress
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Sum V2V Secrecy Rate Maximization for RIS-Assisted Vehicular Communication Systems with Spectrum Sharing
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作者 LI Zhiwei LI Demin CHEN Xuemin 《Journal of Donghua University(English Edition)》 2026年第1期68-79,共12页
Vehicular communication systems rely on secure vehicle-to-vehicle(V2V)communications for safety-critical information exchange.However,the presence of eavesdropping vehicles poses a significant challenge.This paper inv... Vehicular communication systems rely on secure vehicle-to-vehicle(V2V)communications for safety-critical information exchange.However,the presence of eavesdropping vehicles poses a significant challenge.This paper investigates the security of V2V communications in reconfigurable intelligent surface(RIS)-assisted vehicular communication systems with spectrum sharing.It proposes a three-stage alternating optimization(TSAO)algorithm to address the complex problem of multiple eavesdropped V2V links that reuse the spectrum already occupied by vehicle-toinfrastructure(V2I)links.To solve the mixed-integer and non-convex optimization problem due to coupled variables and complex constraints,the algorithm decomposes the original problem into three easily solvable sub-problems:RIS reflection coefficient optimization,vehicle transmission power optimization,and spectrum sharing optimization.First,the RIS reflection coefficients are optimized by using the penalty convex-concave procedure(CCP)method.Second,the optimal power points are determined in the power optimization sub-problem.Finally,the spectrum sharing optimization sub-problem is constructed as a weighted bipartite graph matching problem and solved by using the optimal matching algorithm.The TSAO algorithm not only maximizes the sum V2V secrecy rate but also ensures the quality-of-service(QoS)requirements of the V2I links.Simulation results validate the superiority of the proposed algorithm and highlight the improvement in the sum V2V secrecy rate achieved by utilizing RIS technology in vehicular communication systems with spectrum sharing. 展开更多
关键词 vehicle-to-vehicle(V2V)communication eavesdropping vehicle reconfigurable intelligent surface(RIS) secrecy rate spectrum sharing
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Explainable Ensemble Learning Framework for Early Detection of Autism Spectrum Disorder:Enhancing Trust,Interpretability and Reliability in AI-Driven Healthcare
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作者 Menwa Alshammeri Noshina Tariq +2 位作者 NZ Jhanji Mamoona Humayun Muhammad Attique Khan 《Computer Modeling in Engineering & Sciences》 2026年第1期1233-1265,共33页
Artificial Intelligence(AI)is changing healthcare by helping with diagnosis.However,for doctors to trust AI tools,they need to be both accurate and easy to understand.In this study,we created a new machine learning sy... Artificial Intelligence(AI)is changing healthcare by helping with diagnosis.However,for doctors to trust AI tools,they need to be both accurate and easy to understand.In this study,we created a new machine learning system for the early detection of Autism Spectrum Disorder(ASD)in children.Our main goal was to build a model that is not only good at predicting ASD but also clear in its reasoning.For this,we combined several different models,including Random Forest,XGBoost,and Neural Networks,into a single,more powerful framework.We used two different types of datasets:(i)a standard behavioral dataset and(ii)a more complex multimodal dataset with images,audio,and physiological information.The datasets were carefully preprocessed for missing values,redundant features,and dataset imbalance to ensure fair learning.The results outperformed the state-of-the-art with a Regularized Neural Network,achieving 97.6%accuracy on behavioral data.Whereas,on the multimodal data,the accuracy is 98.2%.Other models also did well with accuracies consistently above 96%.We also used SHAP and LIME on a behavioral dataset for models’explainability. 展开更多
关键词 Autism spectrum disorder(ASD) artificial intelligence in healthcare explainable AI(XAI) ensemble learning machine learning early diagnosis model interpretability SHAP LIME predictive analytics ethical AI healthcare trustworthiness
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Possible Spectrums of 3×3 Upper Triangular Operator Matrices 被引量:9
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作者 海国君 阿拉坦仓 《Journal of Mathematical Research and Exposition》 CSCD 2009年第4期649-661,共13页
Let H1, H2 and H3 be infinite dimensional separable complex Hilbert spaces. We denote by M(D,V,F) a 3×3 upper triangular operator matrix acting on Hi +H2+ H3 of theform M(D,E,F)=(A D F 0 B F 0 0 C).For gi... Let H1, H2 and H3 be infinite dimensional separable complex Hilbert spaces. We denote by M(D,V,F) a 3×3 upper triangular operator matrix acting on Hi +H2+ H3 of theform M(D,E,F)=(A D F 0 B F 0 0 C).For given A ∈ B(H1), B ∈ B(H2) and C ∈ B(H3), the sets ∪D,E,F^σp(M(D,E,F)),∪D,E,F ^σr(M(D,E,F)),∪D,E,F ^σc(M(D,E,F)) and ∪D,E,F σ(M(D,E,F)) are characterized, where D ∈ B(H2,H1), E ∈B(H3, H1), F ∈ B(H3,H2) and σ(·), σp(·), σr(·), σc(·) denote the spectrum, the point spectrum, the residual spectrum and the continuous spectrum, respectively. 展开更多
关键词 3×3 upper triangular operator matrices point spectrum continuous spectrum residual spectrum spectrum.
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