The authors regret to report the following error made in“Spatiotemporal dynamics of neuron differentiation and migration in the developing human spinal cord;52(2025)-101283-1295;Doi:https://doi.org/10.1016/j.jgg.2025...The authors regret to report the following error made in“Spatiotemporal dynamics of neuron differentiation and migration in the developing human spinal cord;52(2025)-101283-1295;Doi:https://doi.org/10.1016/j.jgg.2025.08.004”.In Tables S1 and S2 in the supplementary materials of this paper,some items were written in Chinese.The corresponding pictures and tables were not uploaded in time.展开更多
Spatial transcriptomics technology provides novel insights into the spatial organization of gene expression during embryonic development.In this study,we propose a method that integrates analysis across both temporal ...Spatial transcriptomics technology provides novel insights into the spatial organization of gene expression during embryonic development.In this study,we propose a method that integrates analysis across both temporal and spatial dimensions to investigate spatial transcriptomics data from mouse embryos at different developmental stages.We quantified the spatial expression pattern of each gene at various stages by calculating its Moran’s I.Furthermore,by employing time-series clustering to identify dynamic co-expression modules,we identified several developmentally stage-specific regulatory gene modules.A key finding was the presence of distinct,stage-specific gene network modules across different developmental periods:Early modules focused on morphogenesis,mid-stage on organ development,and late-stage on neural and tissue maturation.Functional enrichment analysis further confirmed the core biological functions of each module.The dynamic,spatially-resolved gene expression model constructed in this study not only provides new biological insights into the programmed spatiotemporal reorganization of gene regulatory networks during embryonic development but also presents an effective approach for analyzing complex spatiotemporal omics data.This work provides a new perspective for understanding developmental biology,regenerative medicine,and related fields.展开更多
Urban open spaces(UOS)play a crucial role in enhancing city livability and resident well-being,yet there remains a gap in utilizing social media to analyze changes in UOS utilization across different COVID(Corona Viru...Urban open spaces(UOS)play a crucial role in enhancing city livability and resident well-being,yet there remains a gap in utilizing social media to analyze changes in UOS utilization across different COVID(Corona Virus Disease)-19 phases.Our research applied Sina Weibo data to scrutinize UOS engagement across pre-pandemic(2019),pandemic(2021),and post-pandemic(2023)periods in Lanzhou City,China,revealing evolving spatiotemporal patterns and highlighting the pandemic's impact on UOS usage.Initially,scenic mountains and urban parks dominated visitor preferences in 2019.However,during the pandemic,there was a trend towards destinations that combined elements of tourism,business,entertainment,and culture,reflecting a growing appetite for diverse experiences.Despite this shift,the post-pandemic period did not see a complete return to pre-pandemic travel patterns,with a noticeable decline in visits to traditional green open spaces during lockdowns.We identified key attractions in main urban areas,highlighting geographical variations in tourism and Cultural Ecosystem Services(CES)distribution that warrant further attention.The post-pandemic landscape reveals a resurging interest in green-blue spaces and nature-focused tourism,highlighting a continued preference for cultural and natural experiences,and emphasizing the need to harmonize development with the preservation of natural and cultural heritage.This study introduces the use of social media data across pandemic phases to guide UOS management,offering insights for creating resilient,multifunctional urban spaces that address public needs and enhance community well-being.展开更多
The sustainable development has been seriously challenged by global climate change due to carbon emissions. As a developing country, China promised to reduce 40%-45% below the level of the year 2005 on its carbon inte...The sustainable development has been seriously challenged by global climate change due to carbon emissions. As a developing country, China promised to reduce 40%-45% below the level of the year 2005 on its carbon intensity by 2020. The realization of this target depends on not only the substantive transition of society and economy at the national scale, but also the action and share of energy saving and emissions reduction at the provincial scale. Based on the method provided by the IPCC, this paper examines the spati- otemporal dynamics and dominating factors of China＇s carbon intensity from energy con- sumption in 1997-2010. The aim is to provide scientific basis for policy making on energy conservation and carbon emission reduction in China. The results are shown as follows. Firstly, China＇s carbon emissions increased from 4.16 Gt to 11.29 Gt from 1997 to 2010, with an annual growth rate of 7.15%, which was much lower than that of GDP （11.72%）. Secondly, the trend of Moran＇s I indicated that China＇s carbon intensity has a growing spatial agglom- eration at the provincial scale. The provinces with either high or low values appeared to be path-dependent or space-locked to some extent. Third, according to spatial panel economet- ric model, energy intensity, energy structure, industrial structure and urbanization rate were the dominating factors shaping the spatiotemporal patterns of China＇s carbon intensity from energy consumption. Therefore, in order to realize the targets of energy conservation and emission reduction, China should improve the efficiency of energy utilization, optimize energy and industrial structure, choose the low-carbon urbanization approach and implement regional cooperation strategy of energy conservation and emissions reduction.展开更多
Electric power consumption(EPC)is one of the basic indices for evaluating electric power use.Obtaining timely and accurate data on the spatiotemporal dynamics of EPC is crucial for understanding and practical deployme...Electric power consumption(EPC)is one of the basic indices for evaluating electric power use.Obtaining timely and accurate data on the spatiotemporal dynamics of EPC is crucial for understanding and practical deployment of electric power resources.In this study,an EPC model was developed using stable nighttime lights time-series data from the Defense Meteorological Satellite Program Operational Linescan System(DMSP/OLS).The model was used to reconstruct the spatial patterns of EPC in Chinese Mainland at the county level from 1995 to 2008.In addition,the spatiotemporal dynamics of EPC were analyzed,and the fol-lowing conclusions were drawn.(1)The EPC model reliably represented the spatiotemporal dynamics of EPC in Chinese Mainland with approximately 70%accuracy.(2)The EPC in most regions of Chinese Mainland was at low to moderate levels,with marked temporal and spatial variations;of high-level EPC,58.26%was concentrated in eastern China.Six urban agglomerations(Beijing-Tianjin-Tangshan region,Shanghai-Nanjing-Hangzhou region,Pearl River Delta,Shandong Peninsula,middle-south of Liaoning Province,and Sichuan Basin)accounted for 10.69%of the total area of Chinese Mainland but consumed 39.23%of the electricity.(3)The EPC of most regions in Chinese Mainland increased from 1995 to 2008,and 64%of the mainland area showed a significant increase in EPC.Moderate increases in EPC were found in 61.62%of eastern China and 80.65%of central China from 1995 to 2008,whereas 75.69%of western China showed no significant increase in EPC.Meanwhile,77.27%,89.35%,and 66.72%of the Shanghai-Nanjing-Hangzhou region,Pearl River Delta,and Shandong Peninsula,respectively,showed high-speed increases in EPC.Moderate increases in EPC occurred in 71.12%and 72.13%of the Beijing-Tianjin-Tangshan region and middle-south of Liaoning Province,respectively,while no significant increase occurred in 56.34%of the Sichuan Basin.展开更多
Plasmonic vortices confining orbital angular momentums to surface have aroused wide research interest in the last decade.Recent advances of near-field microscopes have enabled the study on the spatiotemporal dynamics ...Plasmonic vortices confining orbital angular momentums to surface have aroused wide research interest in the last decade.Recent advances of near-field microscopes have enabled the study on the spatiotemporal dynamics of plasmonic vortices,providing a better understanding of optical orbital angular momentums in the evanescent wave regime.However,these works only focused on the objective characterization of plasmonic vortex and have not achieved subjectively tailoring of its spatiotemporal dynamics for specific applications.Herein,it is demonstrated that the plasmonic vortices with the same topological charge can be endowed with distinct spatiotemporal dynamics by simply changing the coupler design.Based on a near-field scanning terahertz microscopy,the surface plasmon fields are directly obtained with ultrahigh spatiotemporal resolution,experimentally exhibiting the generation and evolution divergences during the whole lifetime of plasmonic vortices.The proposed strategy is straightforward and universal,which can be readily applied into visible or infrared frequencies,facilitating the development of plasmonic vortex related researches and applications.展开更多
In this study,we developed an evaluation index system for green total-factor water-use efficiency(GTFWUE)which reflected both economic and green efficiencies of water resource utilization.Then we measured the GTFWUE o...In this study,we developed an evaluation index system for green total-factor water-use efficiency(GTFWUE)which reflected both economic and green efficiencies of water resource utilization.Then we measured the GTFWUE of 30 provinces/municipalities/autonomous regions(hereafter provinces)in China(not including Tibet,Hong Kong region,Macao region,Taiwan region of China as no data)from 2000 to 2018 using a minimum distance to the strong frontier model that contained an undesirable output.We further analyzed the regional differences and spatial correlations of GTFWUE using these values based on Global and Local Moran’s I statistics,and empirically determined the factors affecting GTFWUE using a spatial econometric model.The evaluation results revealed that the GTFWUE differed substantially between the regions.The provinces with high and low GTFWUE values were located in the coastal and inland areas of China,respectively.The eastern region had a significantly higher GTFWUE than the central and western regions.The GTFWUEs for all three regions(eastern,central,and western regions)decreased slowly from 2000 to 2011(except 2005),remained stable from 2012 to 2016,and rapidly increased in 2017 before decreasing again in 2018.We found significant spatial correlations between the provincial GTFWUEs.The GTFWUE for most provinces belonged to the high-high or low-low cluster region,revealing a significant spatial clustering effect of provincial GTFWUEs.We also found that China’s GTFWUE was highly promoted by economic growth,population size,opening-up level,and urbanization level,and was evidently hindered by water endowment,technological progress,and government influence.However,the water-use structure had little impact on GTFWUE.This study fully demonstrated that the water use mode would be improved,and water resources needed to be used more efficiently and green in China.Moreover,based on the findings of this study,several policy recommendations were proposed from the aspects of cross-regional cooperation,economy,society,and institution.展开更多
Climate-induced shifts in the composition and structure of alpine vegetation cover,both expansion and reduction,are altering alpine ecosystem functions.However,accurately quantifying variations over large-scale region...Climate-induced shifts in the composition and structure of alpine vegetation cover,both expansion and reduction,are altering alpine ecosystem functions.However,accurately quantifying variations over large-scale regions requires a detailed characterization of the fine-scale mosaic vegetation covers.In this study,we employed a regression-based unmixing model using synthetic data to develop a multi-temporal machine learning model aimed to esti-mate the fractions of alpine plant functional types(PFTs)from 1984 to 2024 in the Yarlung Zangbo River Basin(YZRB),China.The estimated cover fractions for tree cover,shrub cover and herbac-eous cover had mean absolute errors of 10.36%,14.06%and 13.38%,respectively.The variations in the fractions of each alpine PFT revealed a slight increase in tree cover and shrub cover,along-side a contraction in herbaceous cover.Specifically,tree cover and shrub cover expanded by+1.54%and+1.83%per decade,respec-tively,while herbaceous cover declined at a rate of 1.98%per decade.These variations were predominantly observed at higher elevations(4000-6000 m),on shaded aspects,and on lower slopes.The variations in these fractions are also positively correlated with air temperature and soil moisture in most regions.This study pro-vides new insights into vegetation cover shifts in this ecologically sensitive region.展开更多
Based on the Terrestrial Ecosystem Model(TEM 5.0), together with the data of climate(temperature, precipitation and solar radiation) and environment(grassland vegetation types, soil texture, altitude, longitude and la...Based on the Terrestrial Ecosystem Model(TEM 5.0), together with the data of climate(temperature, precipitation and solar radiation) and environment(grassland vegetation types, soil texture, altitude, longitude and latitude, and atmospheric CO2 concentration data), the spatiotemporal variations of carbon storage and density, and their controlling factors were discussed in this paper. The results indicated that:(1) the total carbon storage of China's grasslands with a total area of 394.93×104 km2 was 59.47 Pg C. Among them, there were 3.15 Pg C in vegetation and 56.32 Pg C in soil carbon. China's grasslands covering 7.0–11.3% of the total world's grassland area had 1.3–11.3% of the vegetation carbon and 9.7–22.5% of the soil carbon in the world grasslands. The total carbon storage increased from 59.13 to 60.16 Pg C during 1961–2013 with an increasing rate of 19.4 Tg C yr^(-1).(2) The grasslands in the Qinghai-Tibetan Plateau contributed most to the total carbon storage during 1961–2013, accounting for 63.2% of the total grassland carbon storage, followed by Xinjiang grasslands(15.8%) and Inner Mongolia grasslands(11.1%).(3) The vegetation carbon storage showed an increasing trend, with the average annual growth rate of 9.62 Tg C yr^(-1) during 1961–2013, and temperature was the main determinant factor, explaining approximately 85% of its variation. The vegetation carbon storage showed an increasing trend in most grassland regions, however, a decreasing trend in the central grassland in the southern China, the western and central parts of the Inner Mongolian grasslands as well as some parts on the Qinghai-Tibetan Plateau. The soil carbon storage showed a significantly increasing trend with a rate of 7.96 Tg C yr^(-1), which resulted from the interaction of more precipitation and low temperature in the 1980 s and 1990 s. Among them, precipitation was the main determinant factor of increasing soil carbon increases of China's grasslands.展开更多
The major brassinosteroid （BR） receptor of Arabidopsis BRASSINOSTEROID INSENSITIVE1 （BRI1） plays fundamental roles in BR signaling, but the molecular mechanisms underlying the effects of BR on BRI1 internalization...The major brassinosteroid （BR） receptor of Arabidopsis BRASSINOSTEROID INSENSITIVE1 （BRI1） plays fundamental roles in BR signaling, but the molecular mechanisms underlying the effects of BR on BRI1 internalization and assembly state remain unclear. Here, we applied variable angle total internal reflection fluorescence microscopy and fluorescence cross-correlation spectroscopy to analyze the dynamics of GFP-tagged BRII. We found that, in response to BR, the degree of co-localization of BRI1-GFP with AtFIotl-mCherry increased, and especially BR stimulated the membrane microdomain-associated pathway of BRI1 internalization. We also verified these observations in endocytosis-defective chc2-1 mutants and the AtFIotl amiRNA 15-5 lines. Furthermore, examination of the phosphorylation status of bril-EMS-suppressor 1 and measurement of BR-responsive gene expression revealed that membrane microdomains affect BR signaling. These results suggest that BR promotes the partitioning of BRI1 into functional membrane microdomains to activate BR signaling.展开更多
As the COVID-19 pandemic continues to spread, the global tourism industry is facing enormous challenges. There is an urgent need to explore an effective path for tourism to recover and revitalize. With the normalizati...As the COVID-19 pandemic continues to spread, the global tourism industry is facing enormous challenges. There is an urgent need to explore an effective path for tourism to recover and revitalize. With the normalization of the epidemic, tourism destinations will pay more attention to the prevention, warning, and coping strategies of the epidemic, and this focus will also be evident in the study of tourism destination resilience in the post-epidemic period. Some studies on the epidemic and the resilience of tourism are currently underway, but few of them are integrated with research on the resilience of tourism destinations in the post-epidemic period, although no systematic research ideas or methods have been found. Based on resilience theory, this paper summarizes the general research ideas and develops an epidemic resilience model suitable for urban tourism destinations. The present study also proposes a set of research methods based on the index system to analyze the resilience and its spatiotemporal dynamic characteristics of tourism destinations in the post-epidemic period. The methodology can be divided into three stages: Firstly, construct the conceptual model and evaluation system for tourism destination resilience;Secondly, select case sites for empirical analysis, measure the resilience of tourism destinations, and analyze the characteristics of spatiotemporal differences and subsequent factors of influence;And finally, establish an adaptive management mechanism for tourism destinations to use in response to the epidemic and in guiding the formulation of post-epidemic recovery policies.展开更多
Obtaining timely and accurate data on the spatiotemporal dynamics of electric power consumption(EPC)is crucial for the effective utilization of electric power in China.The Defense Meteorological Satellite Program’s O...Obtaining timely and accurate data on the spatiotemporal dynamics of electric power consumption(EPC)is crucial for the effective utilization of electric power in China.The Defense Meteorological Satellite Program’s Operational Linescan System(DMSP/OLS)nighttime stable light(NSL)data have good potential for estimating EPC effectively at large scales.However,saturated lighted pixels contained within the NSL data limit the accuracy of EPC estimation.We developed a new method to correct the saturated lighted pixels,using the SPOT VEGETATION(SPOT/VGT)10-day synthesis product(S10)normalized differ-ence vegetation index(NDVI)data and then modeled the spatiotemporal dynamics of EPC in China' Mainland from 2000 to 2008.The results demon-strated the reliability of our approach with an average Rvalue of 0.93(P<0.001)and an average relative error of-28.92%.EPC in China' Mainland showed an average annual growth rate of 13.46% during the study period from 1198.23 billion kWh in 2000 to 3290.51 billion kWh in 2008.EPC in China' Mainland also showed clear regional variation.Northern coastal China and eastern coastal China consumed 37.61%of the total EPC in China' Mainland,with only 25.96% of the population and 6.11% of the area.展开更多
China has experienced urbanization at an unprecedented rate over the past decades. Against this background, this paper demonstrates the multi-level spatiotemporal urban sprawl process from 1983 to 2007 on the perspect...China has experienced urbanization at an unprecedented rate over the past decades. Against this background, this paper demonstrates the multi-level spatiotemporal urban sprawl process from 1983 to 2007 on the perspective of urban agglomeration with a case study in Southern Jiangsu. Based on a combination of eight rounds of satellite images from 1983 to 2007, the presented results suggest the following three main findings： （1） At the prefecture-city level, the urban sprawl in Southern Jiangsu has presented significantly divergent growth patterns, with more than half of this vast growth occurring in the Suzhou prefecture-level city. （2） At the county level, clear spatial differentiations exist in the direction of the urban sprawl. The centroids of all county seats in the Suzhou and Wuxi prefecture-level cities have an eastward tendency （Shanghai oriented）, while those of the county seats in the Changzhou prefecture-level city tend to be westward （Nanjing oriented）. （3） At the township level, two convergent groups have gradually formed over time; namely, the low density urban zone in the western hilly land and the high density urban zone around the three central downtown areas. The urban areas close to urban cores tend to merge, showing a high-density convergent growth pattern, as do the western and southwestern townships in Southern Jiangsu, showing a low-density convergent growth pattern. All of these findings may be valuable for researchers and local authorities in providing reference for regional coordinated growth, environmental management, and urban planning decision-making.展开更多
Spiral waves have been observed in the biological experiments on rat cortex perfused with drugs which can block inhibitory synapse and switch neuron excitability from type II to type I. To simulate the spiral waves ob...Spiral waves have been observed in the biological experiments on rat cortex perfused with drugs which can block inhibitory synapse and switch neuron excitability from type II to type I. To simulate the spiral waves observed in the experiment, the spatiotemporal patterns are investigated in a network composed of neurons with type I and II excitabilities and excitatory coupling. Spiral waves emerge when the percentage(p) of neurons with type I excitability in the network is at middle levels, which is dependent on the coupling strength. Compared with other spatial patterns which appear at different p values, spiral waves exhibit optimal spatial correlation at a certain spatial frequency, implying the occurrence of spatial coherence resonance-like phenomenon. Some dynamical characteristics of the network such as mean firing frequency and synchronous degree can be well interpreted with distinct properties between type I excitability and type II excitability. The results not only identify dynamics of spiral waves in neuronal networks composed of neurons with different excitabilities, but also are helpful to understanding the emergence of spiral waves observed in the biological experiment.展开更多
Wet-salted skin,as a special artificial high-salt environment,is rich in protein,fat,collagen and other nutrient substrates,and is a rich resource of halotolerant and halophilic microorganisms.However,knowledge gaps r...Wet-salted skin,as a special artificial high-salt environment,is rich in protein,fat,collagen and other nutrient substrates,and is a rich resource of halotolerant and halophilic microorganisms.However,knowledge gaps regarding the microbial community structure and inter taxa associations of wet-salted skin are large.In this study,the spatiotemporal dynamics and community structure of microorganisms present on wet-salted goatskins were investigated using 16S rRNA gene amplicon sequencing and culturable technique.Alpha diversity analysis based on Sobs,Chao,Ace and Shannon indices revealed that microbial diversity on the wet-salted goatskins exhibited a trend of‘down→up→down→flat’with time.During preservation,genera belonging to the bacteria domain such as Aci-netobacter,Weissella and Streptococcus were slowly dying out,whereas those belonging to halophilic archaea such as Natrialba and Haloterrigena were gradually flourishing.Moreover,to resist high-salt stress,microorganisms on the wet-salted goatskin gradually migrated from the outside to the inside,eventually leading to the microbial diversity inside the skin being the same as or even higher than that on the skin surface.Venn diagram analysis revealed that the strains of some genera,including Psychrobacter,Salimicrobium,Salinicola,Ornithinibacillus,Halomonas,Bacillus and Chromohalobacter,were distributed throughout the interior and exterior of the wet-salted goatskin and existed during various periods.Accordingly,45 protease-producing halophilic or halotolerant microorganisms were isolated and screened from the wet-salted goatskin using the gradient dilution plate method.Importantly,16S rRNA genes of some bacteria exhibited less than 99.5%similarity to valid published species,indicating that they likely are novel spe-cies and have a good potential for application.展开更多
Objective:We investigated changes in cortico–subcortical spatiotemporal dynamics to explore the treatment mechanisms oftranscranial alternating current stimulation(tACS)in patientswith Parkinson’s disease(PD).Method...Objective:We investigated changes in cortico–subcortical spatiotemporal dynamics to explore the treatment mechanisms oftranscranial alternating current stimulation(tACS)in patientswith Parkinson’s disease(PD).Methods:Resting-state functional magnetic resonance imaging(rs-fMRI)data were collected from 20 patients with PD and 20 normal controls(NC).Each patient with PD received successivemultidisciplinary intensive rehabilitation treatment and tACStreatment over a one-year interval.Individual functional brain network mapping and co-activation pattern(CAP)analysis were performed to characterize cortico–subcortical dynamics.Results:The same tACS electrode placement stimulated different proportions of functional brain networks across the participants.CAP analysis revealed that the visual network,attentional network,and default mode network co-activated with the thalamus,accumbens,and amygdala,respectively.The pattern characterized by thede-activation of the visual network and the activation of the thalamus showed a significantly low amplitude in the patients with PD than inNCs,and this amplitude increased after tACS treatment.Furthermore,the co-occurrence of cortico–subcortical CAPs was significantly higherin patients with PD than in NCs and decreased after tACS treatment.Conclusions:This study investigated cortico–subcortical spatiotemporaldynamics in patients with PD and further revealed the tACS treatmentmechanism.These findings contribute to understanding cortico–subcortical dynamics and exploring noninvasive neuromodulationtargets of cortico–subcortical circuits in brain diseases,such as PD,Alzheimer’s disease,and depression.展开更多
Although the mechanism of neurovascular coupling remains inadequately understood,physiological research has indicated that the dilation of arterioles located within the cerebral cortex column might represent the prima...Although the mechanism of neurovascular coupling remains inadequately understood,physiological research has indicated that the dilation of arterioles located within the cerebral cortex column might represent the primary mechanism of hemodynamic response during neurovascular coupling.This study examined the spatiotemporal pattern of NO diffusion induced by functional stimuli at column spatial resolution.Our modeling makes it possible to explore the responses of mediating factors to functional stimuli from a four-dimensional view,which may lead the way to decoding the mechanism of neurovascular coupling.展开更多
We numerically study the propagation dynamics of intense optical pulses in gas-filled hollow-core fibers（HCFs）. The spatiotemporal dynamics of the pulses show a transition from tightly confined to loosely confined c...We numerically study the propagation dynamics of intense optical pulses in gas-filled hollow-core fibers（HCFs）. The spatiotemporal dynamics of the pulses show a transition from tightly confined to loosely confined characteristics as the fiber core is increased, which manifests as a deterioration in the spatiotemporal uniformity of the beam. It is found that using the gas pressure gradient does not enhance the beam quality in large-core HCFs, while inducing a positive chirp in the pulse to lower the peak power can improve the beam quality. This indicates that the self-focusing effect in the HCFs is the main driving force for the propagation dynamics. It also suggests that pulses at longer wavelengths are more suitable for HCFs with large cores because of the lower critical power of self-focusing, which is justified by the numerical simulations. These results will benefit the generation of energetic few-cycle pulses in large-core HCFs.展开更多
Soil fauna can sensitively respond to alterations in soil environment induced by land-use changes.However,little is known about the impact of urban land-use changes on earthworm communities.In this study,three land-us...Soil fauna can sensitively respond to alterations in soil environment induced by land-use changes.However,little is known about the impact of urban land-use changes on earthworm communities.In this study,three land-use types(i.e.,forest,nursery and abandoned lands)were chosen to identify differences in diversity,abundance and biomass of earthworm community in Kunming City.Urban land-use had a pronounced difference in species composition,evenness and diversity of earthworm communities.Forest land had the highest density,biomass and diversity of the earthworm communities.Total abundance was dominated by endogeic species in nursery land(70%)and abandoned land(80%),whereas in the forest land,the earthworm community comprised epigeic,endogeic and anecic species.Temporal changes in earthworm density and biomass were also significantly affected by land-use change.Total density and biomass of earthworms in the forest and nursery lands were highest in September,but highest in the abandoned land in October.The influence of soil physicochemical properties on the earthworm density and biomass also varied with land-use types.Soil temperature significantly affected earthworm density and biomass in the three land-use types.Soil pH was positively correlated with earthworm biomass in the forest land,but negatively associated with earthworm density in the abandoned land.Soil organic matter was positively correlated only with density and biomass of earthworms in the nursery and abandoned lands.Our results suggest that the species composition,abundance and biomass of earthworm communities can be determined by the modification of soil properties associated with urban land-use type.展开更多
Investigating the spatiotemporal variation of human activity intensity and its determinants is a crucial basis for further revealing the mechanism of human-environment interaction and optimizing the human development ...Investigating the spatiotemporal variation of human activity intensity and its determinants is a crucial basis for further revealing the mechanism of human-environment interaction and optimizing the human development mode.In this study,the human activity intensity on the Qinghai-Tibet Plateau(QTP)from 1990 to 2020 was measured based on the quantitative model of land use data and the actual regional background,and the under-lying natural and socioeconomic determinants were investigated using spatial econometric methods.The results demonstrate that(1)the human activity intensity in QTP has increased by 11.96%,and there are differences in different spatial scales;the areas with high human activity intensity are distributed in the Hehuang Valley where Xining City and its surrounding areas are located,as well as the One-River and Two-River Area where Lhasa City and surrounding areas are located.(2)Human activity intensity has significant positive spatial spillover,suggesting that local changes will cause changes in the same direction in adjacent areas.(3)The human activ-ity intensity in QTP is affected by various determinants.Concerning socioeconomic factors,the economic level has no significant impact on the human activity intensity in QTP,which differs from the general regional law.Both urbanization and traffic conditions have a significant positive effect,and the impact intensity continues to increase.Concerning natural factors,topographic relief has a significant positive effect;the impacts of temper-ature and vegetation coverage have changed from insignificant to a significant positive effect;the impacts of precipitation and river network density have not been verified;there is no linear relationship between altitude and human activity intensity in the entire QTP,while it exists in local regions.Finally,this study proposes three policy implications for the realization of a more harmonious human-environment relationship in QTP.展开更多
文摘The authors regret to report the following error made in“Spatiotemporal dynamics of neuron differentiation and migration in the developing human spinal cord;52(2025)-101283-1295;Doi:https://doi.org/10.1016/j.jgg.2025.08.004”.In Tables S1 and S2 in the supplementary materials of this paper,some items were written in Chinese.The corresponding pictures and tables were not uploaded in time.
基金supported by the National Natural Science Foundation of China(Grant Nos.12090052,U24A2014,and 12325405).
文摘Spatial transcriptomics technology provides novel insights into the spatial organization of gene expression during embryonic development.In this study,we propose a method that integrates analysis across both temporal and spatial dimensions to investigate spatial transcriptomics data from mouse embryos at different developmental stages.We quantified the spatial expression pattern of each gene at various stages by calculating its Moran’s I.Furthermore,by employing time-series clustering to identify dynamic co-expression modules,we identified several developmentally stage-specific regulatory gene modules.A key finding was the presence of distinct,stage-specific gene network modules across different developmental periods:Early modules focused on morphogenesis,mid-stage on organ development,and late-stage on neural and tissue maturation.Functional enrichment analysis further confirmed the core biological functions of each module.The dynamic,spatially-resolved gene expression model constructed in this study not only provides new biological insights into the programmed spatiotemporal reorganization of gene regulatory networks during embryonic development but also presents an effective approach for analyzing complex spatiotemporal omics data.This work provides a new perspective for understanding developmental biology,regenerative medicine,and related fields.
基金Under the auspices of National Natural Science Foundation of China(No.42401232,72050001)Natural Science Foundation of Gansu Province(No.24JRRA419)Research Funds for Blue Green Infrastructure Planning and Ecological Restoration in Mining Cities(No.071124044/(24)0315)。
文摘Urban open spaces(UOS)play a crucial role in enhancing city livability and resident well-being,yet there remains a gap in utilizing social media to analyze changes in UOS utilization across different COVID(Corona Virus Disease)-19 phases.Our research applied Sina Weibo data to scrutinize UOS engagement across pre-pandemic(2019),pandemic(2021),and post-pandemic(2023)periods in Lanzhou City,China,revealing evolving spatiotemporal patterns and highlighting the pandemic's impact on UOS usage.Initially,scenic mountains and urban parks dominated visitor preferences in 2019.However,during the pandemic,there was a trend towards destinations that combined elements of tourism,business,entertainment,and culture,reflecting a growing appetite for diverse experiences.Despite this shift,the post-pandemic period did not see a complete return to pre-pandemic travel patterns,with a noticeable decline in visits to traditional green open spaces during lockdowns.We identified key attractions in main urban areas,highlighting geographical variations in tourism and Cultural Ecosystem Services(CES)distribution that warrant further attention.The post-pandemic landscape reveals a resurging interest in green-blue spaces and nature-focused tourism,highlighting a continued preference for cultural and natural experiences,and emphasizing the need to harmonize development with the preservation of natural and cultural heritage.This study introduces the use of social media data across pandemic phases to guide UOS management,offering insights for creating resilient,multifunctional urban spaces that address public needs and enhance community well-being.
基金Key Research Program of the Chinese Academy of Sciences, No.KZZD-EW-06-03 No.KSZD-EW-Z-021-03+2 种基金 Key Project of Chinese Ministry of Education, No. 13JJD790008 National Natural Science Foundation of China, No.41329001 No.41071108
文摘The sustainable development has been seriously challenged by global climate change due to carbon emissions. As a developing country, China promised to reduce 40%-45% below the level of the year 2005 on its carbon intensity by 2020. The realization of this target depends on not only the substantive transition of society and economy at the national scale, but also the action and share of energy saving and emissions reduction at the provincial scale. Based on the method provided by the IPCC, this paper examines the spati- otemporal dynamics and dominating factors of China＇s carbon intensity from energy con- sumption in 1997-2010. The aim is to provide scientific basis for policy making on energy conservation and carbon emission reduction in China. The results are shown as follows. Firstly, China＇s carbon emissions increased from 4.16 Gt to 11.29 Gt from 1997 to 2010, with an annual growth rate of 7.15%, which was much lower than that of GDP （11.72%）. Secondly, the trend of Moran＇s I indicated that China＇s carbon intensity has a growing spatial agglom- eration at the provincial scale. The provinces with either high or low values appeared to be path-dependent or space-locked to some extent. Third, according to spatial panel economet- ric model, energy intensity, energy structure, industrial structure and urbanization rate were the dominating factors shaping the spatiotemporal patterns of China＇s carbon intensity from energy consumption. Therefore, in order to realize the targets of energy conservation and emission reduction, China should improve the efficiency of energy utilization, optimize energy and industrial structure, choose the low-carbon urbanization approach and implement regional cooperation strategy of energy conservation and emissions reduction.
基金The National Basic Research Program of China,No.2010CB950901National Natural Science Foundation of China,No.40971059
文摘Electric power consumption(EPC)is one of the basic indices for evaluating electric power use.Obtaining timely and accurate data on the spatiotemporal dynamics of EPC is crucial for understanding and practical deployment of electric power resources.In this study,an EPC model was developed using stable nighttime lights time-series data from the Defense Meteorological Satellite Program Operational Linescan System(DMSP/OLS).The model was used to reconstruct the spatial patterns of EPC in Chinese Mainland at the county level from 1995 to 2008.In addition,the spatiotemporal dynamics of EPC were analyzed,and the fol-lowing conclusions were drawn.(1)The EPC model reliably represented the spatiotemporal dynamics of EPC in Chinese Mainland with approximately 70%accuracy.(2)The EPC in most regions of Chinese Mainland was at low to moderate levels,with marked temporal and spatial variations;of high-level EPC,58.26%was concentrated in eastern China.Six urban agglomerations(Beijing-Tianjin-Tangshan region,Shanghai-Nanjing-Hangzhou region,Pearl River Delta,Shandong Peninsula,middle-south of Liaoning Province,and Sichuan Basin)accounted for 10.69%of the total area of Chinese Mainland but consumed 39.23%of the electricity.(3)The EPC of most regions in Chinese Mainland increased from 1995 to 2008,and 64%of the mainland area showed a significant increase in EPC.Moderate increases in EPC were found in 61.62%of eastern China and 80.65%of central China from 1995 to 2008,whereas 75.69%of western China showed no significant increase in EPC.Meanwhile,77.27%,89.35%,and 66.72%of the Shanghai-Nanjing-Hangzhou region,Pearl River Delta,and Shandong Peninsula,respectively,showed high-speed increases in EPC.Moderate increases in EPC occurred in 71.12%and 72.13%of the Beijing-Tianjin-Tangshan region and middle-south of Liaoning Province,respectively,while no significant increase occurred in 56.34%of the Sichuan Basin.
基金supported by the National Natural Science Foundation of China(62005193,62135008,62075158,62025504,61935015)the National Science Foundation(2114103)Guangxi Key Laboratory of Optoelectroric Information Processing(GD20202).
文摘Plasmonic vortices confining orbital angular momentums to surface have aroused wide research interest in the last decade.Recent advances of near-field microscopes have enabled the study on the spatiotemporal dynamics of plasmonic vortices,providing a better understanding of optical orbital angular momentums in the evanescent wave regime.However,these works only focused on the objective characterization of plasmonic vortex and have not achieved subjectively tailoring of its spatiotemporal dynamics for specific applications.Herein,it is demonstrated that the plasmonic vortices with the same topological charge can be endowed with distinct spatiotemporal dynamics by simply changing the coupler design.Based on a near-field scanning terahertz microscopy,the surface plasmon fields are directly obtained with ultrahigh spatiotemporal resolution,experimentally exhibiting the generation and evolution divergences during the whole lifetime of plasmonic vortices.The proposed strategy is straightforward and universal,which can be readily applied into visible or infrared frequencies,facilitating the development of plasmonic vortex related researches and applications.
基金Under the auspices of Chinese Ministry of Education Humanities and Social Sciences Project(No.19YJCZH241)Project of Chongqing Social Science Planning Project of China(No.2020QNGL38)+1 种基金Science and Technology Research Program of Chongqing Education Commission of China(No.KJQN201901143)Humanities and Social Sciences Research Program of Chongqing Education Commission of China(No.20SKGH169)。
文摘In this study,we developed an evaluation index system for green total-factor water-use efficiency(GTFWUE)which reflected both economic and green efficiencies of water resource utilization.Then we measured the GTFWUE of 30 provinces/municipalities/autonomous regions(hereafter provinces)in China(not including Tibet,Hong Kong region,Macao region,Taiwan region of China as no data)from 2000 to 2018 using a minimum distance to the strong frontier model that contained an undesirable output.We further analyzed the regional differences and spatial correlations of GTFWUE using these values based on Global and Local Moran’s I statistics,and empirically determined the factors affecting GTFWUE using a spatial econometric model.The evaluation results revealed that the GTFWUE differed substantially between the regions.The provinces with high and low GTFWUE values were located in the coastal and inland areas of China,respectively.The eastern region had a significantly higher GTFWUE than the central and western regions.The GTFWUEs for all three regions(eastern,central,and western regions)decreased slowly from 2000 to 2011(except 2005),remained stable from 2012 to 2016,and rapidly increased in 2017 before decreasing again in 2018.We found significant spatial correlations between the provincial GTFWUEs.The GTFWUE for most provinces belonged to the high-high or low-low cluster region,revealing a significant spatial clustering effect of provincial GTFWUEs.We also found that China’s GTFWUE was highly promoted by economic growth,population size,opening-up level,and urbanization level,and was evidently hindered by water endowment,technological progress,and government influence.However,the water-use structure had little impact on GTFWUE.This study fully demonstrated that the water use mode would be improved,and water resources needed to be used more efficiently and green in China.Moreover,based on the findings of this study,several policy recommendations were proposed from the aspects of cross-regional cooperation,economy,society,and institution.
基金supported by the National Natural Science Foundation of China(U22A20567)CAS-ANSO Sustainable Development Research Project(CAS-ANSO-SDRP-2024-04 and CAS-ANSO-SDRP-2024-08)+2 种基金the Sino-Africa Joint Research Center,CAS,China(SAJC202403)the International Science and Technology Cooperation Project of Hubei Province,China(2024EHA035)the Youth Project of Natural Science Foundation of Hubei Province,China(2025AFB393).
文摘Climate-induced shifts in the composition and structure of alpine vegetation cover,both expansion and reduction,are altering alpine ecosystem functions.However,accurately quantifying variations over large-scale regions requires a detailed characterization of the fine-scale mosaic vegetation covers.In this study,we employed a regression-based unmixing model using synthetic data to develop a multi-temporal machine learning model aimed to esti-mate the fractions of alpine plant functional types(PFTs)from 1984 to 2024 in the Yarlung Zangbo River Basin(YZRB),China.The estimated cover fractions for tree cover,shrub cover and herbac-eous cover had mean absolute errors of 10.36%,14.06%and 13.38%,respectively.The variations in the fractions of each alpine PFT revealed a slight increase in tree cover and shrub cover,along-side a contraction in herbaceous cover.Specifically,tree cover and shrub cover expanded by+1.54%and+1.83%per decade,respec-tively,while herbaceous cover declined at a rate of 1.98%per decade.These variations were predominantly observed at higher elevations(4000-6000 m),on shaded aspects,and on lower slopes.The variations in these fractions are also positively correlated with air temperature and soil moisture in most regions.This study pro-vides new insights into vegetation cover shifts in this ecologically sensitive region.
基金supported by the Strategic Priority Research Program–Climate Change:Carbon Budget and Related Issues of the Chinese Academy of Sciences(Grant No.XDA-05050408)
文摘Based on the Terrestrial Ecosystem Model(TEM 5.0), together with the data of climate(temperature, precipitation and solar radiation) and environment(grassland vegetation types, soil texture, altitude, longitude and latitude, and atmospheric CO2 concentration data), the spatiotemporal variations of carbon storage and density, and their controlling factors were discussed in this paper. The results indicated that:(1) the total carbon storage of China's grasslands with a total area of 394.93×104 km2 was 59.47 Pg C. Among them, there were 3.15 Pg C in vegetation and 56.32 Pg C in soil carbon. China's grasslands covering 7.0–11.3% of the total world's grassland area had 1.3–11.3% of the vegetation carbon and 9.7–22.5% of the soil carbon in the world grasslands. The total carbon storage increased from 59.13 to 60.16 Pg C during 1961–2013 with an increasing rate of 19.4 Tg C yr^(-1).(2) The grasslands in the Qinghai-Tibetan Plateau contributed most to the total carbon storage during 1961–2013, accounting for 63.2% of the total grassland carbon storage, followed by Xinjiang grasslands(15.8%) and Inner Mongolia grasslands(11.1%).(3) The vegetation carbon storage showed an increasing trend, with the average annual growth rate of 9.62 Tg C yr^(-1) during 1961–2013, and temperature was the main determinant factor, explaining approximately 85% of its variation. The vegetation carbon storage showed an increasing trend in most grassland regions, however, a decreasing trend in the central grassland in the southern China, the western and central parts of the Inner Mongolian grasslands as well as some parts on the Qinghai-Tibetan Plateau. The soil carbon storage showed a significantly increasing trend with a rate of 7.96 Tg C yr^(-1), which resulted from the interaction of more precipitation and low temperature in the 1980 s and 1990 s. Among them, precipitation was the main determinant factor of increasing soil carbon increases of China's grasslands.
文摘The major brassinosteroid （BR） receptor of Arabidopsis BRASSINOSTEROID INSENSITIVE1 （BRI1） plays fundamental roles in BR signaling, but the molecular mechanisms underlying the effects of BR on BRI1 internalization and assembly state remain unclear. Here, we applied variable angle total internal reflection fluorescence microscopy and fluorescence cross-correlation spectroscopy to analyze the dynamics of GFP-tagged BRII. We found that, in response to BR, the degree of co-localization of BRI1-GFP with AtFIotl-mCherry increased, and especially BR stimulated the membrane microdomain-associated pathway of BRI1 internalization. We also verified these observations in endocytosis-defective chc2-1 mutants and the AtFIotl amiRNA 15-5 lines. Furthermore, examination of the phosphorylation status of bril-EMS-suppressor 1 and measurement of BR-responsive gene expression revealed that membrane microdomains affect BR signaling. These results suggest that BR promotes the partitioning of BRI1 into functional membrane microdomains to activate BR signaling.
基金The Major Project of Beijing Social Science Foundation (19ZDA11)。
文摘As the COVID-19 pandemic continues to spread, the global tourism industry is facing enormous challenges. There is an urgent need to explore an effective path for tourism to recover and revitalize. With the normalization of the epidemic, tourism destinations will pay more attention to the prevention, warning, and coping strategies of the epidemic, and this focus will also be evident in the study of tourism destination resilience in the post-epidemic period. Some studies on the epidemic and the resilience of tourism are currently underway, but few of them are integrated with research on the resilience of tourism destinations in the post-epidemic period, although no systematic research ideas or methods have been found. Based on resilience theory, this paper summarizes the general research ideas and develops an epidemic resilience model suitable for urban tourism destinations. The present study also proposes a set of research methods based on the index system to analyze the resilience and its spatiotemporal dynamic characteristics of tourism destinations in the post-epidemic period. The methodology can be divided into three stages: Firstly, construct the conceptual model and evaluation system for tourism destination resilience;Secondly, select case sites for empirical analysis, measure the resilience of tourism destinations, and analyze the characteristics of spatiotemporal differences and subsequent factors of influence;And finally, establish an adaptive management mechanism for tourism destinations to use in response to the epidemic and in guiding the formulation of post-epidemic recovery policies.
文摘Obtaining timely and accurate data on the spatiotemporal dynamics of electric power consumption(EPC)is crucial for the effective utilization of electric power in China.The Defense Meteorological Satellite Program’s Operational Linescan System(DMSP/OLS)nighttime stable light(NSL)data have good potential for estimating EPC effectively at large scales.However,saturated lighted pixels contained within the NSL data limit the accuracy of EPC estimation.We developed a new method to correct the saturated lighted pixels,using the SPOT VEGETATION(SPOT/VGT)10-day synthesis product(S10)normalized differ-ence vegetation index(NDVI)data and then modeled the spatiotemporal dynamics of EPC in China' Mainland from 2000 to 2008.The results demon-strated the reliability of our approach with an average Rvalue of 0.93(P<0.001)and an average relative error of-28.92%.EPC in China' Mainland showed an average annual growth rate of 13.46% during the study period from 1198.23 billion kWh in 2000 to 3290.51 billion kWh in 2008.EPC in China' Mainland also showed clear regional variation.Northern coastal China and eastern coastal China consumed 37.61%of the total EPC in China' Mainland,with only 25.96% of the population and 6.11% of the area.
基金Acknowledgements This research is supported by the National Natural Science Foundation of China （Grant Nos. 41171325, 41230751, and Jl103408）, Program for New Century Excellent Talents in University （NCET-12-0264）, National Project of Scientific and Technical Supporting Programs Funded by the Ministry of Science ＆ Technology of China （No. 2012BAH28B02）, Fundamental Research Funds for the Central Universities, and Priority Academic Program Development of Jiangsu Higher Education Institutions （PAPD）. The authors are grateful to the Earth Resources Observation and Science Center （EROS, USA） for providing some of the Landsat-5 TM images. Any errors or shortcomings in the paper are the responsibility of the authors.
文摘China has experienced urbanization at an unprecedented rate over the past decades. Against this background, this paper demonstrates the multi-level spatiotemporal urban sprawl process from 1983 to 2007 on the perspective of urban agglomeration with a case study in Southern Jiangsu. Based on a combination of eight rounds of satellite images from 1983 to 2007, the presented results suggest the following three main findings： （1） At the prefecture-city level, the urban sprawl in Southern Jiangsu has presented significantly divergent growth patterns, with more than half of this vast growth occurring in the Suzhou prefecture-level city. （2） At the county level, clear spatial differentiations exist in the direction of the urban sprawl. The centroids of all county seats in the Suzhou and Wuxi prefecture-level cities have an eastward tendency （Shanghai oriented）, while those of the county seats in the Changzhou prefecture-level city tend to be westward （Nanjing oriented）. （3） At the township level, two convergent groups have gradually formed over time; namely, the low density urban zone in the western hilly land and the high density urban zone around the three central downtown areas. The urban areas close to urban cores tend to merge, showing a high-density convergent growth pattern, as do the western and southwestern townships in Southern Jiangsu, showing a low-density convergent growth pattern. All of these findings may be valuable for researchers and local authorities in providing reference for regional coordinated growth, environmental management, and urban planning decision-making.
基金supported by the National Natural Science Foundation of China(Grant Nos.11372224&11572225)
文摘Spiral waves have been observed in the biological experiments on rat cortex perfused with drugs which can block inhibitory synapse and switch neuron excitability from type II to type I. To simulate the spiral waves observed in the experiment, the spatiotemporal patterns are investigated in a network composed of neurons with type I and II excitabilities and excitatory coupling. Spiral waves emerge when the percentage(p) of neurons with type I excitability in the network is at middle levels, which is dependent on the coupling strength. Compared with other spatial patterns which appear at different p values, spiral waves exhibit optimal spatial correlation at a certain spatial frequency, implying the occurrence of spatial coherence resonance-like phenomenon. Some dynamical characteristics of the network such as mean firing frequency and synchronous degree can be well interpreted with distinct properties between type I excitability and type II excitability. The results not only identify dynamics of spiral waves in neuronal networks composed of neurons with different excitabilities, but also are helpful to understanding the emergence of spiral waves observed in the biological experiment.
基金National Key Research and Development Program of China(2017YFB0308401).
文摘Wet-salted skin,as a special artificial high-salt environment,is rich in protein,fat,collagen and other nutrient substrates,and is a rich resource of halotolerant and halophilic microorganisms.However,knowledge gaps regarding the microbial community structure and inter taxa associations of wet-salted skin are large.In this study,the spatiotemporal dynamics and community structure of microorganisms present on wet-salted goatskins were investigated using 16S rRNA gene amplicon sequencing and culturable technique.Alpha diversity analysis based on Sobs,Chao,Ace and Shannon indices revealed that microbial diversity on the wet-salted goatskins exhibited a trend of‘down→up→down→flat’with time.During preservation,genera belonging to the bacteria domain such as Aci-netobacter,Weissella and Streptococcus were slowly dying out,whereas those belonging to halophilic archaea such as Natrialba and Haloterrigena were gradually flourishing.Moreover,to resist high-salt stress,microorganisms on the wet-salted goatskin gradually migrated from the outside to the inside,eventually leading to the microbial diversity inside the skin being the same as or even higher than that on the skin surface.Venn diagram analysis revealed that the strains of some genera,including Psychrobacter,Salimicrobium,Salinicola,Ornithinibacillus,Halomonas,Bacillus and Chromohalobacter,were distributed throughout the interior and exterior of the wet-salted goatskin and existed during various periods.Accordingly,45 protease-producing halophilic or halotolerant microorganisms were isolated and screened from the wet-salted goatskin using the gradient dilution plate method.Importantly,16S rRNA genes of some bacteria exhibited less than 99.5%similarity to valid published species,indicating that they likely are novel spe-cies and have a good potential for application.
基金This work was supported by the National Natural Science Foundation of China(Grant Nos.U20A20191,82071912,12104049,82202291)the Fundamental Research Funds for the Central Universities(Grant No.2021CX11011)the National Key Research and Development Program of China(Grant No.2020YFC2007305).
文摘Objective:We investigated changes in cortico–subcortical spatiotemporal dynamics to explore the treatment mechanisms oftranscranial alternating current stimulation(tACS)in patientswith Parkinson’s disease(PD).Methods:Resting-state functional magnetic resonance imaging(rs-fMRI)data were collected from 20 patients with PD and 20 normal controls(NC).Each patient with PD received successivemultidisciplinary intensive rehabilitation treatment and tACStreatment over a one-year interval.Individual functional brain network mapping and co-activation pattern(CAP)analysis were performed to characterize cortico–subcortical dynamics.Results:The same tACS electrode placement stimulated different proportions of functional brain networks across the participants.CAP analysis revealed that the visual network,attentional network,and default mode network co-activated with the thalamus,accumbens,and amygdala,respectively.The pattern characterized by thede-activation of the visual network and the activation of the thalamus showed a significantly low amplitude in the patients with PD than inNCs,and this amplitude increased after tACS treatment.Furthermore,the co-occurrence of cortico–subcortical CAPs was significantly higherin patients with PD than in NCs and decreased after tACS treatment.Conclusions:This study investigated cortico–subcortical spatiotemporaldynamics in patients with PD and further revealed the tACS treatmentmechanism.These findings contribute to understanding cortico–subcortical dynamics and exploring noninvasive neuromodulationtargets of cortico–subcortical circuits in brain diseases,such as PD,Alzheimer’s disease,and depression.
基金supported by the National Natural Science Foundation of China (Grant No. 30770685)
文摘Although the mechanism of neurovascular coupling remains inadequately understood,physiological research has indicated that the dilation of arterioles located within the cerebral cortex column might represent the primary mechanism of hemodynamic response during neurovascular coupling.This study examined the spatiotemporal pattern of NO diffusion induced by functional stimuli at column spatial resolution.Our modeling makes it possible to explore the responses of mediating factors to functional stimuli from a four-dimensional view,which may lead the way to decoding the mechanism of neurovascular coupling.
文摘We numerically study the propagation dynamics of intense optical pulses in gas-filled hollow-core fibers（HCFs）. The spatiotemporal dynamics of the pulses show a transition from tightly confined to loosely confined characteristics as the fiber core is increased, which manifests as a deterioration in the spatiotemporal uniformity of the beam. It is found that using the gas pressure gradient does not enhance the beam quality in large-core HCFs, while inducing a positive chirp in the pulse to lower the peak power can improve the beam quality. This indicates that the self-focusing effect in the HCFs is the main driving force for the propagation dynamics. It also suggests that pulses at longer wavelengths are more suitable for HCFs with large cores because of the lower critical power of self-focusing, which is justified by the numerical simulations. These results will benefit the generation of energetic few-cycle pulses in large-core HCFs.
基金supported by the China 948Program of National Forestry Bureau(2015-4-39)the National Science Foundation of China(No.41461052+1 种基金31660191)Yunnan education department project(2017YJS089)
文摘Soil fauna can sensitively respond to alterations in soil environment induced by land-use changes.However,little is known about the impact of urban land-use changes on earthworm communities.In this study,three land-use types(i.e.,forest,nursery and abandoned lands)were chosen to identify differences in diversity,abundance and biomass of earthworm community in Kunming City.Urban land-use had a pronounced difference in species composition,evenness and diversity of earthworm communities.Forest land had the highest density,biomass and diversity of the earthworm communities.Total abundance was dominated by endogeic species in nursery land(70%)and abandoned land(80%),whereas in the forest land,the earthworm community comprised epigeic,endogeic and anecic species.Temporal changes in earthworm density and biomass were also significantly affected by land-use change.Total density and biomass of earthworms in the forest and nursery lands were highest in September,but highest in the abandoned land in October.The influence of soil physicochemical properties on the earthworm density and biomass also varied with land-use types.Soil temperature significantly affected earthworm density and biomass in the three land-use types.Soil pH was positively correlated with earthworm biomass in the forest land,but negatively associated with earthworm density in the abandoned land.Soil organic matter was positively correlated only with density and biomass of earthworms in the nursery and abandoned lands.Our results suggest that the species composition,abundance and biomass of earthworm communities can be determined by the modification of soil properties associated with urban land-use type.
基金the National Natural Sci-ence Foundation of China(Grant No.42001139)the Second Ti-betan Plateau Scientific Expedition and Research Program(Grant No.2019QZKK0406)+1 种基金the National Natural Science Foundation of China(Grant No.42230510)the China Postdoctoral Science Foundation(Grant No.2020M670472).
文摘Investigating the spatiotemporal variation of human activity intensity and its determinants is a crucial basis for further revealing the mechanism of human-environment interaction and optimizing the human development mode.In this study,the human activity intensity on the Qinghai-Tibet Plateau(QTP)from 1990 to 2020 was measured based on the quantitative model of land use data and the actual regional background,and the under-lying natural and socioeconomic determinants were investigated using spatial econometric methods.The results demonstrate that(1)the human activity intensity in QTP has increased by 11.96%,and there are differences in different spatial scales;the areas with high human activity intensity are distributed in the Hehuang Valley where Xining City and its surrounding areas are located,as well as the One-River and Two-River Area where Lhasa City and surrounding areas are located.(2)Human activity intensity has significant positive spatial spillover,suggesting that local changes will cause changes in the same direction in adjacent areas.(3)The human activ-ity intensity in QTP is affected by various determinants.Concerning socioeconomic factors,the economic level has no significant impact on the human activity intensity in QTP,which differs from the general regional law.Both urbanization and traffic conditions have a significant positive effect,and the impact intensity continues to increase.Concerning natural factors,topographic relief has a significant positive effect;the impacts of temper-ature and vegetation coverage have changed from insignificant to a significant positive effect;the impacts of precipitation and river network density have not been verified;there is no linear relationship between altitude and human activity intensity in the entire QTP,while it exists in local regions.Finally,this study proposes three policy implications for the realization of a more harmonious human-environment relationship in QTP.
