The Yarlung Tsangpo River(YTR),located in the Himalayan orogenic belt,is renowned for its deep gorges and complex tectonic features,as well as its reputation as a landslide-prone region.However,less is known about the...The Yarlung Tsangpo River(YTR),located in the Himalayan orogenic belt,is renowned for its deep gorges and complex tectonic features,as well as its reputation as a landslide-prone region.However,less is known about the distribution of landslides across the entire river basin.To address this gap in knowledge,this study first established a comprehensive landslide inventory across the entire basin using remote sensing mapping and multiple field investigations.Then,a systematic analysis of the spatial and size distributions was conducted.The results indicated that the YTR basin features at least 2390 landslides with areas exceeding 104 m2,spanning a total area and volume of 1087.6 km^(2) and 48.4 km^(3),respectively.These landslides can be classified into eight types,and rockslides are the most common(53.1%).Their distributions are highly asymmetric,with the following notable patterns:(1)the Tsangpo suture zone(53.4%)contains a greater number of landslides than other tectonic units;(2)the landslide size is influenced by the relief and elevation conditions,with positive relationships observed between the local relief and landslide area,as well as between the elevation range and landslide area;and(3)the landslide distribution is not significantly correlated with rainfall,and seasonally frozen ground is associated with a greater concentration of landslides.Alternating slate and shale groups in the Tsangpo suture zone may be the factors responding to landslide concentration.A total of 20.6%of landslide-blocked rivers were observed,with some forming river knickpoints.Due to the limited data,spatial and size analyses are perhaps immature,and further systematic analysis remains necessary.展开更多
Alzheimer’s disease(AD)is the most common form of dementia.In addition to the lack of effective treatments,there are limitations in diagnostic capabilities.The complexity of AD itself,together with a variety of other...Alzheimer’s disease(AD)is the most common form of dementia.In addition to the lack of effective treatments,there are limitations in diagnostic capabilities.The complexity of AD itself,together with a variety of other diseases often observed in a patient’s history in addition to their AD diagnosis,make deciphering the molecular mechanisms that underlie AD,even more important.Large datasets of single-cell RNA sequencing,single-nucleus RNA-sequencing(snRNA-seq),and spatial transcriptomics(ST)have become essential in guiding and supporting new investigations into the cellular and regional susceptibility of AD.However,with unique technology,software,and larger databases emerging;a lack of integration of these data can contribute to ineffective use of valuable knowledge.Importantly,there was no specialized database that concentrates on ST in AD that offers comprehensive differential analyses under various conditions,such as sex-specific,region-specific,and comparisons between AD and control groups until the new Single-cell and Spatial RNA-seq databasE for Alzheimer’s Disease(ssREAD)database(Wang et al.,2024)was introduced to meet the scientific community’s growing demand for comprehensive,integrated,and accessible data analysis.展开更多
We conducted acoustical surveys with a horizontal beam transducer to detect fish and with a vertical beam transducer to detect depth and macrophytes in two typical shallow lakes along the middle and lower reaches of t...We conducted acoustical surveys with a horizontal beam transducer to detect fish and with a vertical beam transducer to detect depth and macrophytes in two typical shallow lakes along the middle and lower reaches of the Changjiang(Yangtze) River in November 2013. Both lakes are subject to active fish management with annual stocking and removal of large fish. The purpose of the study was to compare hydroacoustic horizontal beam estimates with fish landings. The preliminary results show that the fish distribution patterns dif fered in the two lakes and were af fected by water depth and macrophyte coverage. The hydroacoustically estimated fish biomass matched the commercial catch very well in Niushan Lake, but it was two times higher in Kuilei Lake. However, acoustic estimates included all fish, whereas the catch included only fish >45 cm(smaller ones were released). We were unable to determine the proper regression between acoustic target strength and fish length for the dominant fish species in the two lakes.展开更多
To study the three-dimensional spatial and temporal distributions of dust in tunneling roadways,and to solve the problems of inadequate time and limited number of monitoring points,this paper designs a device for the ...To study the three-dimensional spatial and temporal distributions of dust in tunneling roadways,and to solve the problems of inadequate time and limited number of monitoring points,this paper designs a device for the real-time monitoring and storage of data on the concentrations of dust at multiple measuring points in the same section of a tunnel.The proposed device can measure the total concentration of dust and that of respirable dust in real time at different instances and locations,and using different working procedures.These measurements are used to study the temporal and spatial migration of dust.The results show that there was a sharp fluctuation zone 0–25 m from the heading face,about 25–40 m was high speed subsidence,beyond 40 m was gentle subsidence,The change of respiratory dust is much smoother.At different distances from the heading face,the total dust concentration exhibited a process of“violent oscillation–rapid descent–stable descent,”while the respirable dust exhibited a process of“fluctuating ascent–gradual subsidence.”Changes in the concentrations of total dust and respirable dust dust were consistent at different positions in the same section of the tunnel.The concentration of dust near the wall was low,and those along the sidewalk and air duct of the roadway were slightly higher than in the middle.The concentration of dust farther down the air duct decreased more slowly than that in the remaining lines of measurement.Small amounts of dust featuring large particles settled quickly.High concentrations of dust were observed to be intermittent,and the background value of dust concentration within 100 m of heading face was between 0.5 and 3 mg/m3.展开更多
Spatial distribution is fundamental for understanding species coexistence mechanisms in forest communities.Here we comprehensively explored fine-scale spatial patterns of tree species in a secondary warm-temperate dec...Spatial distribution is fundamental for understanding species coexistence mechanisms in forest communities.Here we comprehensively explored fine-scale spatial patterns of tree species in a secondary warm-temperate deciduous broad-leaved forest community in north China.Aggregated distribution patterns were predominant.Species functional traits had no significant effects on their spatial patterns.The aggregation intensity decreased with increasing DBH and abundance.The multivariate linear stepwise regression showed that abundance and maximum DBH were correlated with the aggregation intensity.Our results partially confirm that species attributes(abundance,DBH)and habitat heterogeneity may primarily contribute to spatial patterns and species coexistence in this secondary forest.展开更多
The latitude-altitude distributions of radiative fluxes and heating rates are investigated by utilizing CloudSat satellite data over China during summer. The Tibetan Plateau causes the downward shortwave fluxes of the...The latitude-altitude distributions of radiative fluxes and heating rates are investigated by utilizing CloudSat satellite data over China during summer. The Tibetan Plateau causes the downward shortwave fluxes of the lower atmosphere over central China to be smaller than the fluxes over southern and northern China by generating more clouds. The existence of a larger quantity of clouds over central China reflects a greater amount of solar radiation back into space. The vertical gradients of upward shortwave radiative fluxes in the atmosphere below 8 km are greater than those above 8 km. The latitudinal-altitude distributions of downward longwave radiative fluxes show a slantwise decreasing trend from low latitudes to high latitudes that gradually weaken in the downward direction. The upward longwave radiative fluxes also weaken in the upward direction but with larger gradients. The maximum heating rates by solar radiation and cooling rates by longwave infrared radiation are located over 28 40°N at 7 8 km mean sea level (MSL), and they are larger than the rates in the northern and southern regions. The heating and cooling rates match well both vertically and geographically.展开更多
Ecological interactions of species and thus their spatial pat- terns may differ between homogeneous and heterogeneous forests. To account for this, techniques of point pattern analysis were implemented on mapped locat...Ecological interactions of species and thus their spatial pat- terns may differ between homogeneous and heterogeneous forests. To account for this, techniques of point pattern analysis were implemented on mapped locations of tree individuals from two 1-ha tropicalforest plots in Vietnam. We analyzed the effect of environmental heterogeneity on tree distributions; spatial distribution patterns of dominant species; inter-specific associations; and conspecific associations between life stages. Our analyses showed that： environmental conditions were homo- geneous at plot 1 but heterogeneous at plot 2; in both plots, all six domi- nant species were aggregated at various scales up to 30 m, and tree spe- cies were aggregated at larger scales in the homogeneous site than in the heterogeneous site; attraction between pairs of species was remarkably higher at the homogeneous site while negative associations were more frequent in the heterogeneous site; some species, H. kurzii, T. ilicifolia （homogeneous plot） and D. sylvatica, S. wightianum （heterogeneous plot） showed a lack of early life-stage individuals near conspecific adults. Moreover, additional clustering of young individuals was independent from conspecific adults, except D. sylvatica in both sites. These findings are consistent with the Janzen-ConneU hypothesis. Overall, habitat het- erogeneity influences spatial patterns and inter-specific associations of the tree species and evidences of self-thinning are shown in most species.展开更多
This study used spatial autoregression(SAR)model and geographically weighted regression(GWR)model to model the spatial patterns of farmland density and its temporal change in Gucheng County,Hubei Province,China in 199...This study used spatial autoregression(SAR)model and geographically weighted regression(GWR)model to model the spatial patterns of farmland density and its temporal change in Gucheng County,Hubei Province,China in 1999 and 2009,and discussed the difference between global and local spatial autocorrelations in terms of spatial heterogeneity and non-stationarity.Results showed that strong spatial positive correlations existed in the spatial distributions of farmland density,its temporal change and the driving factors,and the coefficients of spatial autocorrelations decreased as the spatial lag distance increased.SAR models revealed the global spatial relations between dependent and independent variables,while the GWR model showed the spatially varying fitting degree and local weighting coefficients of driving factors and farmland indices(i.e.,farmland density and temporal change).The GWR model has smooth process when constructing the farmland spatial model.The coefficients of GWR model can show the accurate influence degrees of different driving factors on the farmland at different geographical locations.The performance indices of GWR model showed that GWR model produced more accurate simulation results than other models at different times,and the improvement precision of GWR model was obvious.The global and local farmland models used in this study showed different characteristics in the spatial distributions of farmland indices at different scales,which may provide the theoretical basis for farmland protection from the influence of different driving factors.展开更多
As the key precursors of O_(3),anthropogenic non-methane volatile organic compounds(NMVOCs)have been studied intensively.This paper performed a meta-analysis on the spatial and temporal variations of NMVOCs,their role...As the key precursors of O_(3),anthropogenic non-methane volatile organic compounds(NMVOCs)have been studied intensively.This paper performed a meta-analysis on the spatial and temporal variations of NMVOCs,their roles in photochemical reactions,and their sources in China,based on published research.The results showed that both nonmethane hydrocarbons(NMHCs)and oxygenated VOCs(OVOCs)in China have higher mixing ratios in the eastern developed cities compared to those in the central and western areas.Alkanes are the most abundant NMHCs species in all reported sites while formaldehyde is the most abundant among the OVOCs.OVOCs have the highest mixing ratios in summer and the lowest in winter,which is opposite to NMHCs.Among all NMVOCs,the top eight species account for 50%−70%of the total ozone formation potential(OFP)with different compositions and contributions in different areas.In devolved regions,OFP-NMHCs are the highest in winter while OFP-OVOCs are the highest in summer.Based on positive matrix factorization(PMF)analysis,vehicle exhaust,industrial emissions,and solvent usage in China are the main sources for NMHCs.However,the emission trend analysis showed that solvent usage and industrial emissions will exceed vehicle exhaust and become the two major sources of NMVOCs in near future.Based on the meta-analysis conducted in this work,we believe that the spatio-temporal variations and oxidation mechanisms of atmospheric OVOCs,as well as generating a higher spatial resolution of emission inventories of NMVOCs represent an area for future studies on NMVOCs in China.展开更多
The present study attempted to evaluate the influence of human activity on major elements （Na2O, MgO, A1203, SiO2, K2O, CaO, Fe203）, and to find a method to explore correlations between major elements and human dist...The present study attempted to evaluate the influence of human activity on major elements （Na2O, MgO, A1203, SiO2, K2O, CaO, Fe203）, and to find a method to explore correlations between major elements and human disturbances, according to geospatial theories and methods. The study results indicate that landscapes influence major elements in diverse ways： Al2O3 is closely related to road and mine landscapes; strong relationships exist between MgO, Fe2O3, CaO, and SiO2 and roads; Na2O, SiO2, and Fe2O3 are unrelated to city landscapes; and Na2O is unrelated to road and mine landscapes.展开更多
Long chain alkyl diols have shown important potential for the reconstruction of sea surface temperature,productivities and upwelling conditions in marine or lacustrine environments.However,little is known about the di...Long chain alkyl diols have shown important potential for the reconstruction of sea surface temperature,productivities and upwelling conditions in marine or lacustrine environments.However,little is known about the distribution and sources of the diols in eastern China marginal seas(CMS),which are areas of important organic carbon sink.Here the contents of C_(30) and C_(32)1,15-diols were analyzed in 181 surface sediments from eastern CMS.The similar distribution pattern and strong linear correlation between C_(30) and C_(32) diols indicated that they had similar biological source,with a dominance of C_(30) diol.Their contents ranged from 7-2726 ng g^(-1) for C_(30) diol and 5-669 ng g^(-1) for C_(32) diol,and both showed higher values mainly in the mud area of the Yellow Sea,while the TOC normalized contents showed a more obvious seaward increasing trend.The similar distribution pattern and significant positive correlation between diols and the other marine biomarkers(brassicasterol,dinosterol,C_(37) alkenones) indicated C_(30) and C_(32) diols in eastern CMS were mainly from marine algae.This conclusion was also supported by principal component analysis(PCA).Our results also showed that sediment diol contents were generally related to marine productivity,suggesting that diols could be applied for marine productivity reconstruction in eastern CMS.展开更多
The investigation was conducted on the spatial and temporal distributions of soil organic mater （SOM） in the mixed plantations of alder （Aluns crernastogyne） and cypress （Cupressus funebris ） （MPAC）, which dis...The investigation was conducted on the spatial and temporal distributions of soil organic mater （SOM） in the mixed plantations of alder （Aluns crernastogyne） and cypress （Cupressus funebris ） （MPAC）, which distributed in the hilly areas of central Sichuan Basin （HACSB）. The results show that： （1） the spatial distribution of SOM among different sites at the same age are not significant before 15-year-old, but significant at 20-year-old, and not significant again after 25-year-old; （2） the SOM contents in 0-15 cm and 15-30 cm layers increase sharply from 10- to 15-year-old, and decline gradually from 15- to 30- year-old; the SOM contents of the 30-year-old PCP were 80. 38% and 78.42% higher than that of the 10-year-old, but 29.16% and 53.37% lower than that of 15-year-old in the 0-15 cm and 15-30 cm layers, respectively. The decrease of SOM contents would lead to the degradation of soil fertility and the decline of forest productivity.展开更多
By Monte Carlo simulations, the effect of the dispersion of particle size distribution on the spatial density distributions and correlations of a quasi one-dimensional polydisperse granular gas with fractal size distr...By Monte Carlo simulations, the effect of the dispersion of particle size distribution on the spatial density distributions and correlations of a quasi one-dimensional polydisperse granular gas with fractal size distribution is investigated in the same inelasticity. The dispersive degree of the particle size distribution can be measured by a fractal dimension dr, and the smooth particles are constrained to move along a circle of length L, colliding inelastically with each other and thermalized by a viscosity heat bath. When the typical relaxation time τ of the driving Brownian process is longer than the mean collision time To, the system can reach a nonequilibrium steady state. The average energy of the system decays exponentially with time towards a stable asymptotic value, and the energy relaxation time τB to the steady state becomes shorter with increasing values of df. In the steady state, the spatial density distribution becomes more clusterized as df increases, which can be quantitatively characterized by statistical entropy of the system. Furthermore, the spatial correlation functions of density and velocities are found to be a power-law form for small separation distance of particles, and both of the correlations become stronger with the increase of df. Also, tile density clusterization is explained from the correlations.展开更多
The spatial and temporal distributions of the cotton bollworm (Helicoverpa armigera Hubner) eggs on summer corn seeded at early-, middle- and late-times were studied in 1998 -1999 in Hengshui, Hebei Province in North ...The spatial and temporal distributions of the cotton bollworm (Helicoverpa armigera Hubner) eggs on summer corn seeded at early-, middle- and late-times were studied in 1998 -1999 in Hengshui, Hebei Province in North China. There were several egg peaks during the period from the middle to late August, which were coincided with the pollen-shedding or blister stage of summer corn depending on the change of bollworm occurrence. The eggs were mainly deposited on silks of ears, and leaves and sheaths above the ears. The number of eggs laid on middle- and late-seeded summer corn were higher than that on the early-planted one, resulting in more heavy damage the on late-seeded corn.展开更多
Road silt loading(sL)is an important parameter in the fugitive road dust(FRD)emissions.In this study,the improved Testing Re-entrained Aerosol Kinetic Emissions from Roads(TRAKER)combined with the AP-42 method was fir...Road silt loading(sL)is an important parameter in the fugitive road dust(FRD)emissions.In this study,the improved Testing Re-entrained Aerosol Kinetic Emissions from Roads(TRAKER)combined with the AP-42 method was firstly developed to quickly measure and estimate the sLs of paved roads in Beijing,China.The annual average sLs in Beijing was 0.59±0.31 g/m^(2)in 2020,and decreased by 22.4%compared with that in 2019.The seasonal variations of sLs followed the order of spring>winter>summer>autumn in the two years.The seasonal mean road sLs on the same type road in the four seasons presented a decline trend from^(2)019 to 2020,especially on the Expressway,decreasing 47.4%-72.7%.The road sLs on the different type roads in the same season followed the order of Major arterial∼Minor arterial∼Branch road>Express road,and Township road∼Country highway>Provincial highway∼National highway.The emission intensities of PM10 and PM_(2.5)from FRD in Beijing in 2020 were lower than those in 2019.The PM10 and PM_(2.5)emission intensities at the four planning areas in the two years all presented the order of the capital functional core area>the urban functional expansion area>the urban development new area>the ecological conservation and development area.The annual emissions of PM10 and PM_(2.5)from FRD in Beijing in 2020 were 74,886 ton and 18,118 ton,respectively,decreasing by∼33.3%compared with those in 2019.展开更多
Carbon emissions resulting from energy consumption have become a pressing issue for governments worldwide.Accurate estimation of carbon emissions using satellite remote sensing data has become a crucial research probl...Carbon emissions resulting from energy consumption have become a pressing issue for governments worldwide.Accurate estimation of carbon emissions using satellite remote sensing data has become a crucial research problem.Previous studies relied on statistical regression models that failed to capture the complex nonlinear relationships between carbon emissions and characteristic variables.In this study,we propose a machine learning algorithm for carbon emissions,a Bayesian optimized XGboost regression model,using multi-year energy carbon emission data and nighttime lights(NTL)remote sensing data from Shaanxi Province,China.Our results demonstrate that the XGboost algorithm outperforms linear regression and four other machine learning models,with an R^(2)of 0.906 and RMSE of 5.687.We observe an annual increase in carbon emissions,with high-emission counties primarily concentrated in northern and central Shaanxi Province,displaying a shift from discrete,sporadic points to contiguous,extended spatial distribution.Spatial autocorrelation clustering reveals predominantly high-high and low-low clustering patterns,with economically developed counties showing high-emission clustering and economically relatively backward counties displaying low-emission clustering.Our findings show that the use of NTL data and the XGboost algorithm can estimate and predict carbon emissionsmore accurately and provide a complementary reference for satellite remote sensing image data to serve carbon emission monitoring and assessment.This research provides an important theoretical basis for formulating practical carbon emission reduction policies and contributes to the development of techniques for accurate carbon emission estimation using remote sensing data.展开更多
Coking industry is a potential source of heavy metals(HMs)pollution.However,its impacts to the groundwater of surrounding residential areas have not been well understood.This study investigated the pollution character...Coking industry is a potential source of heavy metals(HMs)pollution.However,its impacts to the groundwater of surrounding residential areas have not been well understood.This study investigated the pollution characteristics and health risks of HMs in groundwater nearby a typical coking plant.Nine HMs including Fe,Zn,Mo,As,Cu,Ni,Cr,Pb and Cd were analyzed.The average concentration of total HMswas higher in the nearby area(244.27μg/L)than that of remote area away the coking plant(89.15μg/L).The spatial distribution of pollution indices including heavy metal pollution index(HPI),Nemerow index(NI)and contamination degree(CD),all demonstrated higher values at the nearby residential areas,suggesting coking activity could significantly impact the HMs distribution characteristics.Four sources of HMs were identified by Positive Matrix Factorization(PMF)model,which indicated coal washing and coking emission were the dominant sources,accounted for 40.4%,and 31.0%,respectively.Oral ingestionwas found to be the dominant exposure pathway with higher exposure dose to children than adults.Hazard quotient(HQ)values were below 1.0,suggesting negligible non-carcinogenic health risks,while potential carcinogenic risks were from Pb and Ni with cancer risk(CR)values>10−6.Monte Carlo simulation matched well with the calculated results with HMs concentrations to be the most sensitive parameters.This study provides insights into understanding how the industrial coking activities can impact the HMs pollution characteristics in groundwater,thus facilitating the implement of HMs regulation in coking industries.展开更多
Synthetic phenolic antioxidants(SPAs)are widely used in diverse industries due to their exceptional antioxidant characteristics.However,human exposure to SPAs may cause health problems.In this study,226 dust samples w...Synthetic phenolic antioxidants(SPAs)are widely used in diverse industries due to their exceptional antioxidant characteristics.However,human exposure to SPAs may cause health problems.In this study,226 dust samples were collected from 10 provinces in China,and six SPAs(three parent SPAs and their three transformation products)were analyzed.The concentrations of6SPAs(the sum of six target compounds)ranged from 15.4 to 3210 ng/g(geometric mean(GM):169 ng/g).The highest concentration of6SPAswas found in Sichuan Province(GM:349 ng/g),which was approximately 4 times higher than that in Hubei Province(81.6 ng/g)(p<0.05).The concentrations of butylated hydroxytoluene(BHT),2,2'-methylene bis(4-methyl-6–tert-butylphenol)(AO2246),2,6-di–tert–butyl–1,4-benzoquinone(BHT-Q),2,6-di–tert–butyl–4-(hydroxymethyl)phenol(BHT-OH),and ∑_(p)-SPAs were substantially higher in dust from urban areas than rural areas(p<0.05).AO2246 concentration in dust from homes(GM:0.400 ng/g)was about 4 times higher than that in workplaces(0.116 ng/g)(p<0.01).Significantly higherp-SPAs concentrations were found in dust from homes(GM:17.5 ng/g)than workplaces(11.4 ng/g)(p<0.01).The estimated daily intakes(EDIs)of ∑_(6)SPAs exposed through dust ingestion were 0.582,0.342,0.197,0.076,and 0.080 ng/kg bw/day in different age groups,and exposed through dermal contact was 0.358,0.252,0.174,0.167,and 0.177 ng/kg bw/day.EDIs showed that the exposure risks of SPAs decreased with age.This is the first work to determine SPAs in dust from10 provinces in China and investigate the spatial distribution of SPAs in those regions.展开更多
By using the first,second and third electronic burst and transcient source experiment catalogs,a joint analysis of spatial and temporal distributions and hardness ratios of gamma-ray bursts is performed.Turning point ...By using the first,second and third electronic burst and transcient source experiment catalogs,a joint analysis of spatial and temporal distributions and hardness ratios of gamma-ray bursts is performed.Turning point features at C_(max)/C_(min) ~6 are found.This probably indicates the existence of two components of burster population which have distinct spatial distributions.展开更多
基金supported by the National Key R&D Program of China(Grant No.2023YFC3008300)the Science and Technology Research Program of the Institute of Mountain Hazards and Environment,Chinese Academy of Sciences,Chinese Academy of Sciences(Grant No.IMHE-ZYTS-03 and IMHE-ZDRW-03).
文摘The Yarlung Tsangpo River(YTR),located in the Himalayan orogenic belt,is renowned for its deep gorges and complex tectonic features,as well as its reputation as a landslide-prone region.However,less is known about the distribution of landslides across the entire river basin.To address this gap in knowledge,this study first established a comprehensive landslide inventory across the entire basin using remote sensing mapping and multiple field investigations.Then,a systematic analysis of the spatial and size distributions was conducted.The results indicated that the YTR basin features at least 2390 landslides with areas exceeding 104 m2,spanning a total area and volume of 1087.6 km^(2) and 48.4 km^(3),respectively.These landslides can be classified into eight types,and rockslides are the most common(53.1%).Their distributions are highly asymmetric,with the following notable patterns:(1)the Tsangpo suture zone(53.4%)contains a greater number of landslides than other tectonic units;(2)the landslide size is influenced by the relief and elevation conditions,with positive relationships observed between the local relief and landslide area,as well as between the elevation range and landslide area;and(3)the landslide distribution is not significantly correlated with rainfall,and seasonally frozen ground is associated with a greater concentration of landslides.Alternating slate and shale groups in the Tsangpo suture zone may be the factors responding to landslide concentration.A total of 20.6%of landslide-blocked rivers were observed,with some forming river knickpoints.Due to the limited data,spatial and size analyses are perhaps immature,and further systematic analysis remains necessary.
文摘Alzheimer’s disease(AD)is the most common form of dementia.In addition to the lack of effective treatments,there are limitations in diagnostic capabilities.The complexity of AD itself,together with a variety of other diseases often observed in a patient’s history in addition to their AD diagnosis,make deciphering the molecular mechanisms that underlie AD,even more important.Large datasets of single-cell RNA sequencing,single-nucleus RNA-sequencing(snRNA-seq),and spatial transcriptomics(ST)have become essential in guiding and supporting new investigations into the cellular and regional susceptibility of AD.However,with unique technology,software,and larger databases emerging;a lack of integration of these data can contribute to ineffective use of valuable knowledge.Importantly,there was no specialized database that concentrates on ST in AD that offers comprehensive differential analyses under various conditions,such as sex-specific,region-specific,and comparisons between AD and control groups until the new Single-cell and Spatial RNA-seq databasE for Alzheimer’s Disease(ssREAD)database(Wang et al.,2024)was introduced to meet the scientific community’s growing demand for comprehensive,integrated,and accessible data analysis.
基金Supported by the Special Scientific Research Fund of Agriculture Public Welfare Profession of China(No.201303056)the State Key Laboratory of Freshwater Ecology and Biotechnology(No.2011FBZ28)the Science and Technology Research Project of China Three Gorges Corporation(No.CT-12-08-01)
文摘We conducted acoustical surveys with a horizontal beam transducer to detect fish and with a vertical beam transducer to detect depth and macrophytes in two typical shallow lakes along the middle and lower reaches of the Changjiang(Yangtze) River in November 2013. Both lakes are subject to active fish management with annual stocking and removal of large fish. The purpose of the study was to compare hydroacoustic horizontal beam estimates with fish landings. The preliminary results show that the fish distribution patterns dif fered in the two lakes and were af fected by water depth and macrophyte coverage. The hydroacoustically estimated fish biomass matched the commercial catch very well in Niushan Lake, but it was two times higher in Kuilei Lake. However, acoustic estimates included all fish, whereas the catch included only fish >45 cm(smaller ones were released). We were unable to determine the proper regression between acoustic target strength and fish length for the dominant fish species in the two lakes.
文摘To study the three-dimensional spatial and temporal distributions of dust in tunneling roadways,and to solve the problems of inadequate time and limited number of monitoring points,this paper designs a device for the real-time monitoring and storage of data on the concentrations of dust at multiple measuring points in the same section of a tunnel.The proposed device can measure the total concentration of dust and that of respirable dust in real time at different instances and locations,and using different working procedures.These measurements are used to study the temporal and spatial migration of dust.The results show that there was a sharp fluctuation zone 0–25 m from the heading face,about 25–40 m was high speed subsidence,beyond 40 m was gentle subsidence,The change of respiratory dust is much smoother.At different distances from the heading face,the total dust concentration exhibited a process of“violent oscillation–rapid descent–stable descent,”while the respirable dust exhibited a process of“fluctuating ascent–gradual subsidence.”Changes in the concentrations of total dust and respirable dust dust were consistent at different positions in the same section of the tunnel.The concentration of dust near the wall was low,and those along the sidewalk and air duct of the roadway were slightly higher than in the middle.The concentration of dust farther down the air duct decreased more slowly than that in the remaining lines of measurement.Small amounts of dust featuring large particles settled quickly.High concentrations of dust were observed to be intermittent,and the background value of dust concentration within 100 m of heading face was between 0.5 and 3 mg/m3.
基金This study was supported by the National Key R&D Program of China(2017YFC0505601)the National Natural Science Foundation of China(31570630)State Key Laboratory of Forest and Soil Ecology(LFSE2015-13).
文摘Spatial distribution is fundamental for understanding species coexistence mechanisms in forest communities.Here we comprehensively explored fine-scale spatial patterns of tree species in a secondary warm-temperate deciduous broad-leaved forest community in north China.Aggregated distribution patterns were predominant.Species functional traits had no significant effects on their spatial patterns.The aggregation intensity decreased with increasing DBH and abundance.The multivariate linear stepwise regression showed that abundance and maximum DBH were correlated with the aggregation intensity.Our results partially confirm that species attributes(abundance,DBH)and habitat heterogeneity may primarily contribute to spatial patterns and species coexistence in this secondary forest.
基金supported by the National Natural Science Foundation of China(Grant Nos.40875084and40705012)the National Key Technologies R&D Program of China(Grant No.2008BAC40B00)
文摘The latitude-altitude distributions of radiative fluxes and heating rates are investigated by utilizing CloudSat satellite data over China during summer. The Tibetan Plateau causes the downward shortwave fluxes of the lower atmosphere over central China to be smaller than the fluxes over southern and northern China by generating more clouds. The existence of a larger quantity of clouds over central China reflects a greater amount of solar radiation back into space. The vertical gradients of upward shortwave radiative fluxes in the atmosphere below 8 km are greater than those above 8 km. The latitudinal-altitude distributions of downward longwave radiative fluxes show a slantwise decreasing trend from low latitudes to high latitudes that gradually weaken in the downward direction. The upward longwave radiative fluxes also weaken in the upward direction but with larger gradients. The maximum heating rates by solar radiation and cooling rates by longwave infrared radiation are located over 28 40°N at 7 8 km mean sea level (MSL), and they are larger than the rates in the northern and southern regions. The heating and cooling rates match well both vertically and geographically.
基金supported with funds from the Ministry of Education and Training of Vietnam
文摘Ecological interactions of species and thus their spatial pat- terns may differ between homogeneous and heterogeneous forests. To account for this, techniques of point pattern analysis were implemented on mapped locations of tree individuals from two 1-ha tropicalforest plots in Vietnam. We analyzed the effect of environmental heterogeneity on tree distributions; spatial distribution patterns of dominant species; inter-specific associations; and conspecific associations between life stages. Our analyses showed that： environmental conditions were homo- geneous at plot 1 but heterogeneous at plot 2; in both plots, all six domi- nant species were aggregated at various scales up to 30 m, and tree spe- cies were aggregated at larger scales in the homogeneous site than in the heterogeneous site; attraction between pairs of species was remarkably higher at the homogeneous site while negative associations were more frequent in the heterogeneous site; some species, H. kurzii, T. ilicifolia （homogeneous plot） and D. sylvatica, S. wightianum （heterogeneous plot） showed a lack of early life-stage individuals near conspecific adults. Moreover, additional clustering of young individuals was independent from conspecific adults, except D. sylvatica in both sites. These findings are consistent with the Janzen-ConneU hypothesis. Overall, habitat het- erogeneity influences spatial patterns and inter-specific associations of the tree species and evidences of self-thinning are shown in most species.
基金Under the auspices of National Natural Science Foundation of China(No.40601073,41101192,41201571)Fundamental Research Funds for the Central Universities(No.2011PY112,2011QC041,2011QC091)Huazhong Agricultural University Scientific&Technological Self-innovation Foundation(No.2011SC21)
文摘This study used spatial autoregression(SAR)model and geographically weighted regression(GWR)model to model the spatial patterns of farmland density and its temporal change in Gucheng County,Hubei Province,China in 1999 and 2009,and discussed the difference between global and local spatial autocorrelations in terms of spatial heterogeneity and non-stationarity.Results showed that strong spatial positive correlations existed in the spatial distributions of farmland density,its temporal change and the driving factors,and the coefficients of spatial autocorrelations decreased as the spatial lag distance increased.SAR models revealed the global spatial relations between dependent and independent variables,while the GWR model showed the spatially varying fitting degree and local weighting coefficients of driving factors and farmland indices(i.e.,farmland density and temporal change).The GWR model has smooth process when constructing the farmland spatial model.The coefficients of GWR model can show the accurate influence degrees of different driving factors on the farmland at different geographical locations.The performance indices of GWR model showed that GWR model produced more accurate simulation results than other models at different times,and the improvement precision of GWR model was obvious.The global and local farmland models used in this study showed different characteristics in the spatial distributions of farmland indices at different scales,which may provide the theoretical basis for farmland protection from the influence of different driving factors.
基金This work was financially supported by the National Key R&D Plan programs(Grant No.2017YFC0210005)the National Natural Science Foundation of China(Grant No.41773117).
文摘As the key precursors of O_(3),anthropogenic non-methane volatile organic compounds(NMVOCs)have been studied intensively.This paper performed a meta-analysis on the spatial and temporal variations of NMVOCs,their roles in photochemical reactions,and their sources in China,based on published research.The results showed that both nonmethane hydrocarbons(NMHCs)and oxygenated VOCs(OVOCs)in China have higher mixing ratios in the eastern developed cities compared to those in the central and western areas.Alkanes are the most abundant NMHCs species in all reported sites while formaldehyde is the most abundant among the OVOCs.OVOCs have the highest mixing ratios in summer and the lowest in winter,which is opposite to NMHCs.Among all NMVOCs,the top eight species account for 50%−70%of the total ozone formation potential(OFP)with different compositions and contributions in different areas.In devolved regions,OFP-NMHCs are the highest in winter while OFP-OVOCs are the highest in summer.Based on positive matrix factorization(PMF)analysis,vehicle exhaust,industrial emissions,and solvent usage in China are the main sources for NMHCs.However,the emission trend analysis showed that solvent usage and industrial emissions will exceed vehicle exhaust and become the two major sources of NMVOCs in near future.Based on the meta-analysis conducted in this work,we believe that the spatio-temporal variations and oxidation mechanisms of atmospheric OVOCs,as well as generating a higher spatial resolution of emission inventories of NMVOCs represent an area for future studies on NMVOCs in China.
基金supported by the Youth Science Foundation (Grant Nos. 41101174 and 41301094)the Lead Strategic Project of the Chinese Academy of Sciences (Grant No. XDB03030507)+1 种基金the Hundred Young Talents Program of the Institute of Mountain Hazards and Environment (Grant No. SDSQB-2015-02)the Open Fund for Key Laboratory of Geoscience Spatial Information Technology of Ministry of Land and Resources (Grant No. KLGSIT2016-01)
文摘The present study attempted to evaluate the influence of human activity on major elements （Na2O, MgO, A1203, SiO2, K2O, CaO, Fe203）, and to find a method to explore correlations between major elements and human disturbances, according to geospatial theories and methods. The study results indicate that landscapes influence major elements in diverse ways： Al2O3 is closely related to road and mine landscapes; strong relationships exist between MgO, Fe2O3, CaO, and SiO2 and roads; Na2O, SiO2, and Fe2O3 are unrelated to city landscapes; and Na2O is unrelated to road and mine landscapes.
基金supported by the National Natural Science Foundation of China(Nos.41521064 and 41630966)
文摘Long chain alkyl diols have shown important potential for the reconstruction of sea surface temperature,productivities and upwelling conditions in marine or lacustrine environments.However,little is known about the distribution and sources of the diols in eastern China marginal seas(CMS),which are areas of important organic carbon sink.Here the contents of C_(30) and C_(32)1,15-diols were analyzed in 181 surface sediments from eastern CMS.The similar distribution pattern and strong linear correlation between C_(30) and C_(32) diols indicated that they had similar biological source,with a dominance of C_(30) diol.Their contents ranged from 7-2726 ng g^(-1) for C_(30) diol and 5-669 ng g^(-1) for C_(32) diol,and both showed higher values mainly in the mud area of the Yellow Sea,while the TOC normalized contents showed a more obvious seaward increasing trend.The similar distribution pattern and significant positive correlation between diols and the other marine biomarkers(brassicasterol,dinosterol,C_(37) alkenones) indicated C_(30) and C_(32) diols in eastern CMS were mainly from marine algae.This conclusion was also supported by principal component analysis(PCA).Our results also showed that sediment diol contents were generally related to marine productivity,suggesting that diols could be applied for marine productivity reconstruction in eastern CMS.
文摘The investigation was conducted on the spatial and temporal distributions of soil organic mater （SOM） in the mixed plantations of alder （Aluns crernastogyne） and cypress （Cupressus funebris ） （MPAC）, which distributed in the hilly areas of central Sichuan Basin （HACSB）. The results show that： （1） the spatial distribution of SOM among different sites at the same age are not significant before 15-year-old, but significant at 20-year-old, and not significant again after 25-year-old; （2） the SOM contents in 0-15 cm and 15-30 cm layers increase sharply from 10- to 15-year-old, and decline gradually from 15- to 30- year-old; the SOM contents of the 30-year-old PCP were 80. 38% and 78.42% higher than that of the 10-year-old, but 29.16% and 53.37% lower than that of 15-year-old in the 0-15 cm and 15-30 cm layers, respectively. The decrease of SOM contents would lead to the degradation of soil fertility and the decline of forest productivity.
基金supported by National Natural Science Foundation of China under Grant Nos.10675048 and 1068006the Natural Science Foundation of Xianning College under Grant No.KZ0916
文摘By Monte Carlo simulations, the effect of the dispersion of particle size distribution on the spatial density distributions and correlations of a quasi one-dimensional polydisperse granular gas with fractal size distribution is investigated in the same inelasticity. The dispersive degree of the particle size distribution can be measured by a fractal dimension dr, and the smooth particles are constrained to move along a circle of length L, colliding inelastically with each other and thermalized by a viscosity heat bath. When the typical relaxation time τ of the driving Brownian process is longer than the mean collision time To, the system can reach a nonequilibrium steady state. The average energy of the system decays exponentially with time towards a stable asymptotic value, and the energy relaxation time τB to the steady state becomes shorter with increasing values of df. In the steady state, the spatial density distribution becomes more clusterized as df increases, which can be quantitatively characterized by statistical entropy of the system. Furthermore, the spatial correlation functions of density and velocities are found to be a power-law form for small separation distance of particles, and both of the correlations become stronger with the increase of df. Also, tile density clusterization is explained from the correlations.
基金the IPM Research of main diseases and pest insects of corn,National Project No.96-005-01-03the Ministry of Science and Technology,PRC.
文摘The spatial and temporal distributions of the cotton bollworm (Helicoverpa armigera Hubner) eggs on summer corn seeded at early-, middle- and late-times were studied in 1998 -1999 in Hengshui, Hebei Province in North China. There were several egg peaks during the period from the middle to late August, which were coincided with the pollen-shedding or blister stage of summer corn depending on the change of bollworm occurrence. The eggs were mainly deposited on silks of ears, and leaves and sheaths above the ears. The number of eggs laid on middle- and late-seeded summer corn were higher than that on the early-planted one, resulting in more heavy damage the on late-seeded corn.
基金This research was funded by the Development and Demonstration of Road Dust Monitoring and Management System(No.Z191100009119011)the National Research Program for Key Issues in Air Pollution Control China(No.DQGG0201)the National Key Research and Development program of China(No.2018YFC0213203).
文摘Road silt loading(sL)is an important parameter in the fugitive road dust(FRD)emissions.In this study,the improved Testing Re-entrained Aerosol Kinetic Emissions from Roads(TRAKER)combined with the AP-42 method was firstly developed to quickly measure and estimate the sLs of paved roads in Beijing,China.The annual average sLs in Beijing was 0.59±0.31 g/m^(2)in 2020,and decreased by 22.4%compared with that in 2019.The seasonal variations of sLs followed the order of spring>winter>summer>autumn in the two years.The seasonal mean road sLs on the same type road in the four seasons presented a decline trend from^(2)019 to 2020,especially on the Expressway,decreasing 47.4%-72.7%.The road sLs on the different type roads in the same season followed the order of Major arterial∼Minor arterial∼Branch road>Express road,and Township road∼Country highway>Provincial highway∼National highway.The emission intensities of PM10 and PM_(2.5)from FRD in Beijing in 2020 were lower than those in 2019.The PM10 and PM_(2.5)emission intensities at the four planning areas in the two years all presented the order of the capital functional core area>the urban functional expansion area>the urban development new area>the ecological conservation and development area.The annual emissions of PM10 and PM_(2.5)from FRD in Beijing in 2020 were 74,886 ton and 18,118 ton,respectively,decreasing by∼33.3%compared with those in 2019.
基金supported by the Key Research and Development Program in Shaanxi Province,China(No.2022ZDLSF07-05)the Fundamental Research Funds for the Central Universities,CHD(No.300102352901)。
文摘Carbon emissions resulting from energy consumption have become a pressing issue for governments worldwide.Accurate estimation of carbon emissions using satellite remote sensing data has become a crucial research problem.Previous studies relied on statistical regression models that failed to capture the complex nonlinear relationships between carbon emissions and characteristic variables.In this study,we propose a machine learning algorithm for carbon emissions,a Bayesian optimized XGboost regression model,using multi-year energy carbon emission data and nighttime lights(NTL)remote sensing data from Shaanxi Province,China.Our results demonstrate that the XGboost algorithm outperforms linear regression and four other machine learning models,with an R^(2)of 0.906 and RMSE of 5.687.We observe an annual increase in carbon emissions,with high-emission counties primarily concentrated in northern and central Shaanxi Province,displaying a shift from discrete,sporadic points to contiguous,extended spatial distribution.Spatial autocorrelation clustering reveals predominantly high-high and low-low clustering patterns,with economically developed counties showing high-emission clustering and economically relatively backward counties displaying low-emission clustering.Our findings show that the use of NTL data and the XGboost algorithm can estimate and predict carbon emissionsmore accurately and provide a complementary reference for satellite remote sensing image data to serve carbon emission monitoring and assessment.This research provides an important theoretical basis for formulating practical carbon emission reduction policies and contributes to the development of techniques for accurate carbon emission estimation using remote sensing data.
基金supported by the National Key Research and Development Program of China(No.2019YFC1804501)the National Natural Science Foundation of China(Nos.42122056 and U1901210)+2 种基金Guangdong Basic and Applied Basic Research Foundation(No.2021B1515020063)the Key Research and Development Program of Guangdong Province(No.2021B1111380003)the Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program(No.2017BT01Z032).
文摘Coking industry is a potential source of heavy metals(HMs)pollution.However,its impacts to the groundwater of surrounding residential areas have not been well understood.This study investigated the pollution characteristics and health risks of HMs in groundwater nearby a typical coking plant.Nine HMs including Fe,Zn,Mo,As,Cu,Ni,Cr,Pb and Cd were analyzed.The average concentration of total HMswas higher in the nearby area(244.27μg/L)than that of remote area away the coking plant(89.15μg/L).The spatial distribution of pollution indices including heavy metal pollution index(HPI),Nemerow index(NI)and contamination degree(CD),all demonstrated higher values at the nearby residential areas,suggesting coking activity could significantly impact the HMs distribution characteristics.Four sources of HMs were identified by Positive Matrix Factorization(PMF)model,which indicated coal washing and coking emission were the dominant sources,accounted for 40.4%,and 31.0%,respectively.Oral ingestionwas found to be the dominant exposure pathway with higher exposure dose to children than adults.Hazard quotient(HQ)values were below 1.0,suggesting negligible non-carcinogenic health risks,while potential carcinogenic risks were from Pb and Ni with cancer risk(CR)values>10−6.Monte Carlo simulation matched well with the calculated results with HMs concentrations to be the most sensitive parameters.This study provides insights into understanding how the industrial coking activities can impact the HMs pollution characteristics in groundwater,thus facilitating the implement of HMs regulation in coking industries.
基金supported by the National Key Research and Development Program of China(No.2023YFC3706602)the National Natural Science Foundation of China(Nos.22225605 and 22193051)the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDB0750200).
文摘Synthetic phenolic antioxidants(SPAs)are widely used in diverse industries due to their exceptional antioxidant characteristics.However,human exposure to SPAs may cause health problems.In this study,226 dust samples were collected from 10 provinces in China,and six SPAs(three parent SPAs and their three transformation products)were analyzed.The concentrations of6SPAs(the sum of six target compounds)ranged from 15.4 to 3210 ng/g(geometric mean(GM):169 ng/g).The highest concentration of6SPAswas found in Sichuan Province(GM:349 ng/g),which was approximately 4 times higher than that in Hubei Province(81.6 ng/g)(p<0.05).The concentrations of butylated hydroxytoluene(BHT),2,2'-methylene bis(4-methyl-6–tert-butylphenol)(AO2246),2,6-di–tert–butyl–1,4-benzoquinone(BHT-Q),2,6-di–tert–butyl–4-(hydroxymethyl)phenol(BHT-OH),and ∑_(p)-SPAs were substantially higher in dust from urban areas than rural areas(p<0.05).AO2246 concentration in dust from homes(GM:0.400 ng/g)was about 4 times higher than that in workplaces(0.116 ng/g)(p<0.01).Significantly higherp-SPAs concentrations were found in dust from homes(GM:17.5 ng/g)than workplaces(11.4 ng/g)(p<0.01).The estimated daily intakes(EDIs)of ∑_(6)SPAs exposed through dust ingestion were 0.582,0.342,0.197,0.076,and 0.080 ng/kg bw/day in different age groups,and exposed through dermal contact was 0.358,0.252,0.174,0.167,and 0.177 ng/kg bw/day.EDIs showed that the exposure risks of SPAs decreased with age.This is the first work to determine SPAs in dust from10 provinces in China and investigate the spatial distribution of SPAs in those regions.
文摘By using the first,second and third electronic burst and transcient source experiment catalogs,a joint analysis of spatial and temporal distributions and hardness ratios of gamma-ray bursts is performed.Turning point features at C_(max)/C_(min) ~6 are found.This probably indicates the existence of two components of burster population which have distinct spatial distributions.
