Radiation dose reduction in computed tomography(CT)can be achieved by decreasing the number of projections.However,reconstructing CT images via filtered back projection algorithm from sparse-view projections often con...Radiation dose reduction in computed tomography(CT)can be achieved by decreasing the number of projections.However,reconstructing CT images via filtered back projection algorithm from sparse-view projections often contains severe streak artifacts,affecting clinical diagnosis.To address this issue,this paper proposes TransitNet,an iterative unrolling deep neural network that combines model-driven data consistency,a physical a prior constraint,with deep learning’s feature extraction capabilities.TransitNet employs a novel iterative architecture,implementing flexible physical constraints through learnable data consistency operations,utilizing Transformer’s self-attention mechanism to model long-range dependencies in image features,and introducing linear attention mechanisms to reduce self-attention’s computational complexity from quadratic to linear.Extensive experiments demonstrate that this method exhibits significant advantages in both reconstruction quality and computational efficiency,effectively suppressing streak artifacts while preserving structures and details of images.展开更多
Grating-based X-ray phase-contrast imaging enhances the contrast of imaged objects,particularly soft tissues.However,the radiation dose in computed tomography(CT)is generally excessive owing to the complex collection ...Grating-based X-ray phase-contrast imaging enhances the contrast of imaged objects,particularly soft tissues.However,the radiation dose in computed tomography(CT)is generally excessive owing to the complex collection scheme.Sparse-view CT collection reduces the radiation dose,but with reduced resolution and reconstructed artifacts particularly in analytical reconstruction methods.Recently,deep learning has been employed in sparse-view CT reconstruction and achieved stateof-the-art results.Nevertheless,its low generalization performance and requirement for abundant training datasets have hindered the practical application of deep learning in phase-contrast CT.In this study,a CT model was used to generate a substantial number of simulated training datasets,thereby circumventing the need for experimental datasets.By training a network with simulated training datasets,the proposed method achieves high generalization performance in attenuationbased CT and phase-contrast CT,despite the lack of sufficient experimental datasets.In experiments utilizing only half of the CT data,our proposed method obtained an image quality comparable to that of the filtered back-projection algorithm with full-view projection.The proposed method simultaneously addresses two challenges in phase-contrast three-dimensional imaging,namely the lack of experimental datasets and the high exposure dose,through model-driven deep learning.This method significantly accelerates the practical application of phase-contrast CT.展开更多
基金National Natural Science Foundation of China under grant (62071281)Local Science and Technology Development Fund Project Guided by the Central Government under grant (YDZJSX2021A003)。
文摘Radiation dose reduction in computed tomography(CT)can be achieved by decreasing the number of projections.However,reconstructing CT images via filtered back projection algorithm from sparse-view projections often contains severe streak artifacts,affecting clinical diagnosis.To address this issue,this paper proposes TransitNet,an iterative unrolling deep neural network that combines model-driven data consistency,a physical a prior constraint,with deep learning’s feature extraction capabilities.TransitNet employs a novel iterative architecture,implementing flexible physical constraints through learnable data consistency operations,utilizing Transformer’s self-attention mechanism to model long-range dependencies in image features,and introducing linear attention mechanisms to reduce self-attention’s computational complexity from quadratic to linear.Extensive experiments demonstrate that this method exhibits significant advantages in both reconstruction quality and computational efficiency,effectively suppressing streak artifacts while preserving structures and details of images.
基金supported by the National Natural Science Foundation of China(Nos.U2032148,U2032157,11775224)USTC Research Funds of the Double First-Class Initiative(No.YD2310002008)the National Key Research and Development Program of China(No.2017YFA0402904),the Youth Innovation Promotion Association,CAS(No.2020457)。
文摘Grating-based X-ray phase-contrast imaging enhances the contrast of imaged objects,particularly soft tissues.However,the radiation dose in computed tomography(CT)is generally excessive owing to the complex collection scheme.Sparse-view CT collection reduces the radiation dose,but with reduced resolution and reconstructed artifacts particularly in analytical reconstruction methods.Recently,deep learning has been employed in sparse-view CT reconstruction and achieved stateof-the-art results.Nevertheless,its low generalization performance and requirement for abundant training datasets have hindered the practical application of deep learning in phase-contrast CT.In this study,a CT model was used to generate a substantial number of simulated training datasets,thereby circumventing the need for experimental datasets.By training a network with simulated training datasets,the proposed method achieves high generalization performance in attenuationbased CT and phase-contrast CT,despite the lack of sufficient experimental datasets.In experiments utilizing only half of the CT data,our proposed method obtained an image quality comparable to that of the filtered back-projection algorithm with full-view projection.The proposed method simultaneously addresses two challenges in phase-contrast three-dimensional imaging,namely the lack of experimental datasets and the high exposure dose,through model-driven deep learning.This method significantly accelerates the practical application of phase-contrast CT.
