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Evaluation of the versatility of perforators-enhanced rhomboid flap technique for ischial sores reconstruction
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作者 Waleed Aldabaany Ashraf Hussein Elghamry +1 位作者 Montaser Hosny Mohamed Yassin 《Chinese Journal of Plastic and Reconstructive Surgery》 2024年第2期65-71,共7页
Background: Prolonged pressure on the skin known as pressure sores, can cause frequent injuries to the skin and underlying tissues. However, several prevention approaches, including non-surgical and surgical managemen... Background: Prolonged pressure on the skin known as pressure sores, can cause frequent injuries to the skin and underlying tissues. However, several prevention approaches, including non-surgical and surgical management,are available. In flap surgery for pressure sores, a variety of flap types may be used;each offers certain benefits and some incidences of complications and recurrence. This study evaluated the versatility of the perforatorenhanced rhomboid flap technique for ischial sore construction.Methods: This prospective study was conducted in the Plastic Surgery Department of Fayoum University Hospital.The perforator-enhanced rhomboid flap technique was employed in 20 patients with ischial pressure sores who failed to respond to conservative treatment. A proper history was obtained and a preoperative arterial duplex was performed to determine the site of the prominent perforators for their preservation at the base of the flap.Postoperative follow-ups and evaluations were performed.Results: The mean age of the study group was 43.7 ± 13.1, ranging from 19 to 65 years. Moreover, 80% of the participants were males while 20% were female. The main etiology of the sores was paraplegia in 45% of cases.The mean surface area of sores was 24.8 ± 6.3 cm2. In 75% of cases, the color match of the flap was rated as excellent. Similarly, 70% of the patients rated flap thickness as excellent. In 55% of the cases, the scar appearance was deemed excellent. Overall satisfaction was reported as excellent by 40% of the patients, while only 5% reported poor satisfaction. Approximately, 10% of the cases were identified with seroma, and 30% had wound dehiscence of a mean size of 1.33 ± 0.98 cm and required around 6.8 ± 1.9 weeks to heal.Conclusion: The perforator-enhanced rhomboid flap technique is a versatile method for reconstructing ischial pressure sores owing to its technical ease, short operative time, reliable vascularity, aesthetic outcome, matching skin color, and short recovery time. The main limitations include large defects with large surface areas, lack of a nearby donor site for a rhomboid flap, and scarring from prior procedures around the sore. 展开更多
关键词 Ischial pressure sores Perforators-enhanced rhomboid flaps RECONSTRUCTION
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Logistic Regression Analysis and Nursing Interventions for High-risk Factors for Pressure Sores in Patients in a Surgical Intensive Care Unit 被引量:7
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作者 Xin-Ran Wang Bin-Ru Han 《Chinese Nursing Research》 CAS 2015年第2期78-83,共6页
Objective: To investigate the risk factors related to the development of pressure sores in critically ill surgical patients and to establish a basis for the formulation of effective precautions. Methods: A questionn... Objective: To investigate the risk factors related to the development of pressure sores in critically ill surgical patients and to establish a basis for the formulation of effective precautions. Methods: A questionnaire regarding the factors for pressure sores in critically ill surgical patients was created using a case control study with reference to the pertinent literature. After being exam- ined and validated by experts, the questionnaire was used to collect data about critically ill surgical patients in a grade A tertiary hospital. Among the 47 patients enrolled into the study, the 14 who developed nosocomial pressure sores were allocated to the pressure sore group, and the remaining 33 patients who met the inclusion criteria and did not exhibit pressure sores were allocated to the control group. Univariate and multivariate logistic regression analyses were employed to examine the differences in 22 indicators between the two groups in an attempt to identify the risk factors for pressure sores. Results: According to the univariate analyses, the maximum value of lactic acid in the arterial blood, the number of days of norepinephrine use, the number of days of mechanical ventilation, the number of days of blood purification, and the number of days of bowel incontinence were statistically greater in the pressure sore group than in the control group (P〈0.05). The multivariate logistic regression analysis revealed that the number of days of norepinephrine use and the level of lactic acid in the arterial blood were high risk-factors for pressure sores (P〈0.05). Conclusions: The best method for preventing and control pressure sores in surgical critically ill patients is to strongly emphasize the duration of the critical status and to give special attention to patients in a continuous state of shock. The adoption of measures specific to high-risk patient groups and risk factors, including the active control of primary diseases and the application of decompression measures during the treatment of the patients, are helpful for improving the quality of care in the prevention and control of pressure sores in critically ill patients. 展开更多
关键词 Critically ill patients Pressure sores Risk factors Shock Care
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Comparison of postoperative sore throat following laryngoscopy conducted by Miller and Macintosh laryngoscope blades 被引量:1
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作者 Khosro Barkhordari Farhad Etezadi +1 位作者 Reza Shariat Moharari Mohammad Reza Khajavi 《Health》 2011年第10期623-625,共3页
BACKGROUND: Post operative sore throat (PST) is one of the most common complaints after tracheal intubation. In this study we compared the effects of curved and straight laryngoscope blades on severity and incidence o... BACKGROUND: Post operative sore throat (PST) is one of the most common complaints after tracheal intubation. In this study we compared the effects of curved and straight laryngoscope blades on severity and incidence of PST. METHOD: In this prospective randomized clinical trial we evaluated incidence and severity of PST in 147 ASA physical status I–II, aged 18 – 62 y (group Miller, n = 71), (group Macintosh, n = 76) following intubation with Miller and Macintosh laryngoscope blades by using Visual Analog Scale (VAS). RESULTS: The overall incidence of PST in our study was 35.4% (Macintosh group = 39.5% and in Miller group = 31% and P = 0.829). The incidence of PST was not statistically different between two kinds of laryngoscope blades and the mean rank of pain score was not statistically different in recovery room and up to 48 hours after surgery. CONCLUSIONS: Our study showed these types of laryngoscope blade had not association with incidence and severity of PST. . 展开更多
关键词 Post Operative sore THROAT TRACHEAL Incubation LARYNGOSCOPE BLADES
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Strategies of the acupuncture treatment for delayed-onset muscle soreness based on pathophysiology 被引量:1
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作者 Huan ZHONG Yi LIU +7 位作者 Jian XIONG Bin HU Xin PEI Xiao-rong CHANG Mi LIU Xiao-jun WANG Xiang-ning SHAO Xiao-wen TAN 《World Journal of Acupuncture-Moxibustion》 CSCD 2022年第3期245-249,共5页
Based on the pathophysiological analysis of delayed-onset muscle soreness,the key points of its treatment was summarized in this paper:promoting the repair of injury,improving the metabolic state,and effectively relie... Based on the pathophysiological analysis of delayed-onset muscle soreness,the key points of its treatment was summarized in this paper:promoting the repair of injury,improving the metabolic state,and effectively relieving pain.Its key objectives and order of treatment are made clear:first to promote repair,second to improve metabolism,and then to relieve pain.And through the analysis of the key points of the treatment,the law of acupuncture and moxibustion treatment is put forward as follows:puncture those acupoints with the overall regulation function to adjust the secretion of endogenous analgesic substances in the body,at the same time,the special respiratory movement is adopted to improve the metabolic state,and the proper exercises are combined to promote the tissue repair. 展开更多
关键词 Acupuncture and moxibustion Diagnosis and treatment thoughts Delayed-Onset Muscle soreness(DOMS) PATHOPHYSIOLOGY Dǎoyǐn(physical and breathing exercises)
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Effects of Zingiber cassumunar(Plai cream) in the treatment of delayed onset muscle soreness 被引量:1
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作者 Nuttaset Manimmanakorn Apiwan Manimmanakorn +3 位作者 Disaphon Boobphachart Worrawut Thuwakum Wiroon Laupattarakasem Michael J Hamlin 《Journal of Integrative Medicine》 SCIE CAS CSCD 2016年第2期114-120,共7页
OBJECTIVE: To evaluate the effects of Zingiber cassumunar(Plai cream) in either 7% or 14% concentration on delayed onset muscle soreness(DOMS).METHODS: Seventy-five untrained healthy volunteers(28 males and 47 ... OBJECTIVE: To evaluate the effects of Zingiber cassumunar(Plai cream) in either 7% or 14% concentration on delayed onset muscle soreness(DOMS).METHODS: Seventy-five untrained healthy volunteers(28 males and 47 females), performed 4 sets of 25 eccentric repetitions of the dominant quadriceps muscle on an isokinetic dynamometry machine. Participants were then randomized into 3 groups: 14% Plai cream, 7% Plai cream and placebo cream. Two grams of the cream(strips of 5-cm long) were gently rubbed into the quadriceps muscles for 5 min immediately following the exercise and every 8 h thereafter for 7 d in all groups. Muscle soreness, muscle strength, jump height, thigh circumference and creatine kinase were measured before and after eccentric exercise.RESULTS: Compared to the placebo cream the 14% Plai cream substantially reduced muscle soreness over the 7 d by –82%(95% CI = –155% to –6%, P = 0.03), but had similar muscle soreness effects to 7% Plai cream(–34%, –96% to 27%, P = 0.2). Compared to the placebo cream the 7% Plai cream resulted in a small non-significant reduction in muscle soreness levels over the following 7 d(–40%, –116% to 36%, P = 0.3). Compared to placebo cream there was little effect of Plai cream(7% or 14%) on muscle strength, jump height, thigh circumference or creatine kinase concentration. CONCLUSION: Using 14% Plai cream over a 7-day period substantially reduced muscle soreness symptoms compared to 7% Plai cream or a placebo cream. The authors suggest that the administration of 14% Plai cream is a useful alternative in the management of DOMS.TRIAL REGISTRATION: Thai Clinical Trial Registry TCTR20140215001. 展开更多
关键词 Plai cream muscle soreness muscle strength creatine kinase
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Effects of L-carnitine and Branched-Chain Amino Acids on Energy Metabolism,Body Composition,and Delayed-Onset Muscle Soreness after Exercise in Healthy Subjects
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作者 Yoichi Sakurai Yumi Hasegawa +2 位作者 Yuka Kurosaka Hideyuki Nanba Satoshi Odo 《Journal of Nutritional Oncology》 2018年第1期25-33,共9页
Background Specific nutrients combined with exercise may prevent a loss of lean body mass and consequently prevent sarcopenia.We examined the effects of 2 weeks of supplementation with L-carnitine and a single dose of... Background Specific nutrients combined with exercise may prevent a loss of lean body mass and consequently prevent sarcopenia.We examined the effects of 2 weeks of supplementation with L-carnitine and a single dose of branched-chain amino acids(BCAAs)on energy metabolism and body composition before and after exercise and on post-exercise muscle soreness in healthy subjects.Methods A total of 12 young,untrained,healthy women were randomly assigned to two groups who received either 2 weeks of supplementation with L-carnitine(1000 mg/day)and a single dose of BCAAs plus 200 kcal energy(LCAR+BCAA group,n=6)or 200 kcal energy alone(control group,n=6)before 60 min of exercise.Energy substrate metabolism and body composition by bio-impedance were examined before and after exercise.Delayed-onset muscle soreness(DOMS)was evaluated by using a visual analogue scale for 3 days after exercise.Results Serum concentrations of free and acyl-L-carnitine in the LCAR+BCAA group were not significantly different from those in the control group.There were no significant differences in body composition before or after exercise between the two groups.Although serum free fatty acid levels 120 min after the oral ingestion of BCAAs were significantly lower in the LCAR+BCAA group than in the control group,there were no significant differences in serum free fatty acid levels immediately after and 60 min after exercise.DOMS for 3 days after exercise was lower in the LCAR+BCAA group than in the control group,but this difference was not significant.Conclusion Continuous supplementation with L-carnitine combined with a dose of BCAAs in young,untrained,healthy subjects caused a blunted response of stimulated lipolysis after exercise. 展开更多
关键词 SARCOPENIA L-CARNITINE Branched-chain amino ACIDS Exercise Oxidative stress Delayed-onset muscle soreNESS
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Observation on the Curative Effect of Non-invasive Positive Pressure Ventilation Pressure Sore Nursing Intervention for Critically Ill Patients with COPD
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作者 WU Minyi 《外文科技期刊数据库(文摘版)医药卫生》 2021年第11期177-179,共5页
For the critically ill patients with COPD, in order to do a good job of nursing, the article investigates the application effect of nursing intervention on pressure sore caused by non-invasive positive pressure ventil... For the critically ill patients with COPD, in order to do a good job of nursing, the article investigates the application effect of nursing intervention on pressure sore caused by non-invasive positive pressure ventilation. 170 patients in our hospital were selected and the staffs were randomly divided into control group and observation group with equal number of cases. The nursing staff adopted conventional methods to carry out the nursing observation of the patients in the control group. On this basis, combined with the non-invasive positive pressure ventilation pressure sore nursing intervention model, the nursing research of the observation group was carried out. Then, the occurrence probability of pressure sore and nursing satisfaction of the patients in the two groups were compared. For the two groups of patients' nursing satisfaction, the observation group patients' nursing satisfaction was 97.65%, significantly higher than the control group 80.00%, while the observation group's pressure sore incidence rate was 2.35%, the control group's pressure sore incidence rate was 21.18%, data comparison, the observation group's pressure sore incidence rate was significantly lower, the difference between the groups was statistically significant (p < 0.05). It can be seen from this that in order to do a good job in the nursing of critically ill patients with COPD, it is extremely critical for the nursing staff to adopt the non-invasive positive pressure ventilation pressure sore nursing mode. On the basis of keeping close contact with the patients, the occurrence rate of pressure sores can be fundamentally reduced, and the nursing satisfaction of the patients can be comprehensively improved. 展开更多
关键词 COPD noninvasive ventilator pressure sore NURSING
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Application Effect of High-quality Skin Care in the Treatment of Patients with Skin Sores and Its Impact on Their Negative Emotions
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作者 MAWei 《外文科技期刊数据库(文摘版)医药卫生》 2022年第2期038-041,共4页
Objective: to explore the effect of high-quality skin care in the treatment of patients with skin sores and its negative emotion. Methods: 160 patients with skin sores were randomly divided into two groups with 80 cas... Objective: to explore the effect of high-quality skin care in the treatment of patients with skin sores and its negative emotion. Methods: 160 patients with skin sores were randomly divided into two groups with 80 cases in each group. The control group was given routine nursing, and the observation group was given high-quality skin nursing on the basis of the control group. The nursing effect (physical function index, physiological function index), negative emotion (SAS, SDS score) and nursing satisfaction were compared between the two groups. Results: after nursing, the scores of physical function index and physiological function index in the observation group were significantly higher than those in the control group, and the scores of SAS and SDS were significantly lower than those in the control group (P < 0.05).The nursing satisfaction of the observation group was significantly higher than that of the control group (P < 0.05).Conclusion: high quality skin care can significantly improve the physical and physiological functions of patients with skin sores, alleviate their negative emotions and improve their nursing satisfaction. 展开更多
关键词 skin sores quality care negative emotion
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Negative pressure wound therapy with a fenestrated penrose drain for refractory seroma following ischial flap:A case report
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作者 Sungyeon Kim Hong Bae Jeon Dong Hee Kang 《World Journal of Clinical Cases》 2025年第22期115-121,共7页
BACKGROUND Patients with paraplegia are vulnerable to ischial pressure ulcers.Surgical treatments often lead to complications such as seroma and infection,necessitating repeated interventions that increase surgical di... BACKGROUND Patients with paraplegia are vulnerable to ischial pressure ulcers.Surgical treatments often lead to complications such as seroma and infection,necessitating repeated interventions that increase surgical difficulty.This case report aimed to introduce a novel treatment strategy combining negative pressure wound therapy(NPWT)with a fenestrated Penrose drain to manage refractory seroma in patients with a history of ischial pressure ulcers.CASE SUMMARY A 63-year-old woman presented with soft tissue defects on the left ischium and right trochanter.After surgical debridement,an inferior gluteal artery perforator(IGAP)flap was used to reconstruct the left ischium.NPWT was applied at a setting of 75 mmHg on postoperative day 3 owing to the development of seroma,combined with a fenestrated Penrose drain to facilitate effective drainage of serous fluid.A 54-year-old man presented with a 4 cm×2 cm ulcer on the left ischium after previous excision and flap coverage.After thorough debridement,the IGAP flap was elevated,and NPWT with a fenestrated Penrose drain was implemented immediately postoperatively at 75 mmHg to promote drainage.Both patients achieved a stable recovery without complications.CONCLUSION NPWT combined with a fenestrated Penrose drain placement is a promising strategy for addressing refractory seromas in cases of complex pressure ulcers. 展开更多
关键词 Inferior gluteal artery perforator flap Ischial sore Negative pressure wound therapy Penrose drainage Postoperative complication Pressure sore Case report
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清咽滴丸治疗不同证型喉痹的临床研究 被引量:2
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作者 郭英 周慧芳 +10 位作者 阮岩 王嘉玺 马瑞鸿 黎小华 张晓彤 查日田 解本贵 薄建楠 徐世泉 肖巍 胡宇洋 《中国中西医结合耳鼻咽喉科杂志》 2025年第1期44-48,共5页
目的 评价清咽滴丸治疗风热喉痹及痰火郁结喉痹的临床疗效及安全性。方法 采用病例注册登记研究的方法进行临床多中心研究,共观察4375例喉痹患者,由中医辩证为风热证及痰火郁结证,按医嘱服用清咽滴丸,分别于治疗第1天和第7天就主要症状... 目的 评价清咽滴丸治疗风热喉痹及痰火郁结喉痹的临床疗效及安全性。方法 采用病例注册登记研究的方法进行临床多中心研究,共观察4375例喉痹患者,由中医辩证为风热证及痰火郁结证,按医嘱服用清咽滴丸,分别于治疗第1天和第7天就主要症状咽痛进行VAS评分,对各症状消失率及疾病痊愈率等疗效指标进行评价,并观察该药的不良反应。结果 清咽滴丸治疗7天后,风热喉痹及痰火郁结喉痹患者VAS评分变化率分别为(96.45±11.26)%、(94.63±13.70)%,与治疗前相比均有显著降低(P<0.01)。风热证以及痰火郁结证治疗后各临床症状均有显著缓解,差异具有统计学意义。喉痹痊愈率风热证77.01%,痰火郁结证57.78%,清咽滴丸治疗风热证疗效更佳。结论 清咽滴丸治疗风热及痰火郁结喉痹均有较好疗效及安全性,治疗风热证总体疗效优于痰火郁结证。 展开更多
关键词 清咽滴丸 喉痹 急性咽炎 慢性咽炎 急性扁桃体炎 普通感冒
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不同温度冷疗对青年男性运动后延迟性上肢肌肉酸痛的效果比较
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作者 娄彦涛 王家伟 +1 位作者 肖晓飞 李艳辉 《中国康复理论与实践》 北大核心 2025年第9期1074-1082,共9页
目的 比较不同温度冷疗对青年男性运动后上肢延迟性肌肉酸痛(DOMS)疼痛和运动功能的恢复效果。方法 2024年4月至7月,在沈阳体育学院国家体育总局冬季项目技术诊断与技能评定重点实验室选取健康青年男性(22~26岁) 24例,随机均分对照组、... 目的 比较不同温度冷疗对青年男性运动后上肢延迟性肌肉酸痛(DOMS)疼痛和运动功能的恢复效果。方法 2024年4月至7月,在沈阳体育学院国家体育总局冬季项目技术诊断与技能评定重点实验室选取健康青年男性(22~26岁) 24例,随机均分对照组、A组和B组。采用等速肌力测试系统进行肘关节DOMS运动建模;建模后,A组行10℃恒温冷疗10 min,B组行6℃恒温冷疗10 min,对照组自然恢复。建模后即刻、24 h、48 h和72 h,采用等速肌力测试系统测试肘屈肌群60°/s、120°/s和180°/s角速度下相对峰力矩(rPT),无线表面肌电测试系统同步采集肱二头肌肌电振幅均方根(RMS),采用疼痛视觉模拟量表(VAS)评定疼痛。结果 VAS评分、rPT和RMS的组内(F > 15.716, P<0.001)和组间(F > 6.478, P<0.01)主效应均显著。建模后24h、48 h和72 h,VAS评分对照组> A组> B组(P<0.05)。建模后不同时间点及不同角速度下,各组rPT和RMS两两比较结果虽有所不同,但总体上,rPT呈现对照组A组> B组(P<0.05)的趋势。角速度越大,时间越长,趋势越明显。结论 冷疗可缓解青年男性运动后上肢DOMS的疼痛,并促进肌力恢复,恒温6℃冷疗效果更佳。 展开更多
关键词 延迟性肌肉酸痛 上肢 冷疗 疼痛 肌力
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宋金元时期疮疡诊疗发展的影响因素探究
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作者 刘洋 彭奕雯 +3 位作者 陈婉丽 朱建宇 杨晟泱 赵健 《中国中医药现代远程教育》 2025年第18期73-75,共3页
随着中医学理论的发展以及社会因素的影响,疮疡诊疗的技术和方法也在不断进步。文章通过系统梳理宋金元时期影响疮疡诊疗发展的医学内外部因素,总结得出医学理论进步等医学内部因素以及政治变革、经济重心转移、思想文化交融、战争、气... 随着中医学理论的发展以及社会因素的影响,疮疡诊疗的技术和方法也在不断进步。文章通过系统梳理宋金元时期影响疮疡诊疗发展的医学内外部因素,总结得出医学理论进步等医学内部因素以及政治变革、经济重心转移、思想文化交融、战争、气候、生活方式改变等社会因素均对疮疡的诊疗产生了推动作用。聚焦疾病发展影响因素的探究,可为疮疡的古代文献研究提供新的视角,也能为疮疡的现代治疗提供依据和理论支持。 展开更多
关键词 疮疡 宋金元时期 社会因素 文献研究
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明清时期疮疡诊疗发展的影响因素探究
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作者 刘洋 朱建宇 +4 位作者 杨晟泱 彭奕雯 陈婉丽 闫姝颖 赵健 《中国中医药现代远程教育》 2025年第17期187-190,共4页
随着中医理论的发展以及社会的变化,疮疡诊疗的技术和方法不断进步。通过系统梳理明清时期影响疮疡诊疗发展的医学内、外部因素可知,医学理论的进步等医学内部因素,以及政治变革、经济重心转移、思想文化交融、战争、气候、生活方式改... 随着中医理论的发展以及社会的变化,疮疡诊疗的技术和方法不断进步。通过系统梳理明清时期影响疮疡诊疗发展的医学内、外部因素可知,医学理论的进步等医学内部因素,以及政治变革、经济重心转移、思想文化交融、战争、气候、生活方式改变等社会因素,均对疮疡的诊疗产生了推动作用。此文聚焦疾病发展影响因素进行探究,可为疮疡的古代文献研究提供新的视角,也能为疮疡的现代治疗提供依据和理论支持。 展开更多
关键词 明清时期 疮疡 内部因素 社会因素
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池田大作生态哲学的理论来源、核心要义与实践指向
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作者 王明兵 《大连大学学报》 2025年第1期1-7,共7页
池田大作虽然并未以概念界定、逻辑推演和体系构建的运思方式对何谓“生态哲学”做过系统性的学理阐释,但他对人与自然的关系及其关涉人类存在和命运的思考具有极为丰富而深刻的内容。然而,池田大作的职志并不止于认知或理论体系方面的... 池田大作虽然并未以概念界定、逻辑推演和体系构建的运思方式对何谓“生态哲学”做过系统性的学理阐释,但他对人与自然的关系及其关涉人类存在和命运的思考具有极为丰富而深刻的内容。然而,池田大作的职志并不止于认知或理论体系方面的构建,而在于通达实践,既要“转识成智”,也要“知行合一”。就哲学形态而论,池田大作的生态哲学属于实践哲学的领域,是一种独特的哲学贡献。 展开更多
关键词 池田大作 生态哲学 理论来源 核心要义 实践指向
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改良体位管理在达芬奇机器人辅助宫颈癌根治术中的应用
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作者 谢云霞 《河南医学研究》 2025年第5期937-940,共4页
目的探讨在达芬奇机器人辅助宫颈癌根治术中应用改良体位管理的临床效果。方法回顾性分析2021年1月至2023年8月郑州大学第一附属医院完成达芬奇机器人辅助宫颈癌根治术治疗的80例宫颈癌患者资料,所有患者均接受常规的围手术期护理,其中4... 目的探讨在达芬奇机器人辅助宫颈癌根治术中应用改良体位管理的临床效果。方法回顾性分析2021年1月至2023年8月郑州大学第一附属医院完成达芬奇机器人辅助宫颈癌根治术治疗的80例宫颈癌患者资料,所有患者均接受常规的围手术期护理,其中40例接受传统手术体位管理的患者纳入对照组,40例接受改良体位管理的患者纳入观察组。比较两组术中压疮发生情况、手术相关指标、术后身体感受舒适情况。结果观察组术中压疮发生率低于对照组,差异有统计学意义(P<0.05)。观察组体位安置时间、手术时长、下床活动时间均短于对照组,差异有统计学意义(P<0.05)。观察组总舒适率高于对照组,差异有统计学意义(P<0.05)。结论达芬奇机器人辅助宫颈癌根治术中应用改良体位管理,可在照顾患者舒适度的同时,减少术中压疮的发生,实现术后早期下床活动。 展开更多
关键词 宫颈癌 根治术 达芬奇机器人 体位管理 压疮
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Investigation on the Historical Origins of Traditional Chinese Medicine Diagnosis and Treatment of“Ruyong(Breast Abscess)”
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作者 Qi Liu Ke Li +2 位作者 Yazhou Han Mingru Wang Xufeng Cheng 《Chinese Medicine and Natural Products》 2025年第2期86-93,共8页
“Ruyong(breast abscess)”has a high incidence rate.Traditional Chinese medicine(TCM)diagnosis and treatment of this condition demonstrate significant advantages,including diverse therapeuticmethods,outstanding effica... “Ruyong(breast abscess)”has a high incidence rate.Traditional Chinese medicine(TCM)diagnosis and treatment of this condition demonstrate significant advantages,including diverse therapeuticmethods,outstanding efficacy,and high safety.Based on TCM theory and combining relevant ancient texts and modern research,this paper systematically summarizes the different understandings of“Ruyong(breast abscess)”by physicians throughout history in terms of disease names,etiology,pathogenesis,and treatment.The ancient names for Ruyong(breast abscess)were varied,also referred to as“Duru(stagnation in breast)”or“Naichuang(breast sore)”.Its symptoms are diverse,with the main clinical manifestations being localized redness,swelling,heat,pain,and poor milk discharge in the affected breast.The etiology is primarily attributed to“milk stasis”“liver qi stagnation and stomach heat”and“exposure to external pathogens”.Additionally,this paper summarizes the treatment experiences from ancient and modern medical texts and highlights the complementary effects of internal and external therapies.This study provides a reference for modern clinical understanding and treatment of“Ruyong(breast abscess)”in the hope of further improvement of clinical efficacy. 展开更多
关键词 Ruyong breast abscess Duru(stagnation in breast) Naichuang(breast sore) historical origins disease name etiology and pathogenesis treatment methods
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不同浓度罗哌卡因超声引导下喉上神经阻滞对喉罩全身麻醉后咽喉痛的影响 被引量:4
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作者 庞娜 董智刚 +3 位作者 刘卓 杨立群 陈娟 赵蕊 《西北药学杂志》 2025年第1期9-14,共6页
目的 探究不同浓度罗哌卡因超声引导下喉上神经阻滞对喉罩全身麻醉后咽喉痛的影响。方法 回顾性分析2021年1月—2023年12月在唐山职业技术学院附属医院进行喉罩全身麻醉手术的126例患者的资料,根据手术麻醉方案分为对照组、研究A组、研... 目的 探究不同浓度罗哌卡因超声引导下喉上神经阻滞对喉罩全身麻醉后咽喉痛的影响。方法 回顾性分析2021年1月—2023年12月在唐山职业技术学院附属医院进行喉罩全身麻醉手术的126例患者的资料,根据手术麻醉方案分为对照组、研究A组、研究B组,分别为36、49、41例。3组均采用常规全身麻醉诱导后置入喉罩全身麻醉,研究A组和研究B组在喉罩全身麻醉的基础上通过超声引导注射罗哌卡因进行双侧喉上神经阻滞,研究A组罗哌卡因浓度为0.25%,研究B组罗哌卡因浓度为0.50%,对照组仅行喉罩全身麻醉。比较各组围手术期[神经阻滞前(t_(0))、麻醉诱导成功时(t_(1))、喉罩置入后即刻(t_(2))、喉罩拔除后即刻(t_(3))]血流动力学指标、喉罩置入情况、术后咽喉部相关并发症的发生情况、不良反应发生率等。结果 对照组t_(2)、t_(3)的心率、平均动脉压较研究A组和研究B组更高(P<0.05);研究A组和研究B组喉罩一次置入成功率均显著高于对照组(P<0.05);研究A组和研究B组喉罩带血丝阳性率、术后并发症总发生率以及中、重度咽喉痛总发生率均显著低于对照组,且研究B组的术后并发症发生率高于研究A组(P<0.05);t_(3)以及喉罩拔除后6 h患者咽喉痛数字分级评分法(numerical rating scale,NRS)评分均低于对照组(P<0.05);3组间麻醉药物相关不良反应发生率比较差异无统计学差异(P>0.05)。结论 不同浓度罗哌卡因超声引导下喉上神经阻滞均有助于喉罩全身麻醉患者术中生命体征的维持,降低术后咽喉痛的发生率及减轻患者疼痛程度,且低浓度罗哌卡因减少术后并发症的效果更好。 展开更多
关键词 喉上神经阻滞 超声引导 罗哌卡因 喉罩全身麻醉 咽喉痛
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基于“病-药-量”探索黄芪古代用药规律 被引量:2
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作者 曹佳蕾 梁绿圆 +9 位作者 刘宜杭 徐梓铭 王选 魏文希 万和伽 吕星航 李维笑 张煜欣 魏炳琦 任献青 《中国中药杂志》 北大核心 2025年第3期798-811,共14页
该研究利用“病-药-量”体系分析古代典籍中含有黄芪中药方剂的用药规律,为黄芪的临床应用及药品开发提供科学依据。从《中华医典》等古籍数据库中收集含有黄芪的中药方剂,采用Excel 2020建立古代黄芪临证方药数据库,对其病症、证型、... 该研究利用“病-药-量”体系分析古代典籍中含有黄芪中药方剂的用药规律,为黄芪的临床应用及药品开发提供科学依据。从《中华医典》等古籍数据库中收集含有黄芪的中药方剂,采用Excel 2020建立古代黄芪临证方药数据库,对其病症、证型、药物使用频次、功效类别、性味归经、剂型、用量等进行统计分析,运用SPSS statistics 26.0、IBM SPSS Modeler 18.0软件进行关联规则、聚类分析、公因子分析等数据挖掘。经筛选共纳入含黄芪方剂2297首,主治病症233种,其中高频病症7种(频次>25次),主要为疮疡、虚劳、汗病、中风等。治疗疮疡证型以气血两虚为主,虚劳证型以气血亏虚为主,汗病证型以阴阳两虚为主,中风证型以气虚络瘀为主。组方中使用频次>25次的药物有98味,药物功效种类以补气药、补血药较多,使用频次较高的有甘草、当归、人参、白术、陈皮等。配伍中药药性以温、寒为主,药味以甘、辛、苦为主,主要归脾、肺、心、肾、肝经。高频病症剂型及药物用量分析显示,治疗疮疡时,黄芪常用剂量3.73 g,核心药物配伍甘草以生肌敛疮;治疗虚劳时,黄芪常用剂量37.30 g,核心药物配伍人参以补虚益气;治疗汗病时,黄芪常用剂量3.73 g,核心药物配伍甘草以固表止汗;治疗中风时,黄芪常用剂量7.46 g,核心药物配伍甘草以祛风止痉。黄芪在治疗多种系统疾病时,发挥补气升阳、固表止汗、托毒生肌等作用。根据不同疾病表现,与其他药物相配伍时,黄芪又被赋予“生肌敛疮”“补虚益气”“固表止汗”“祛风益气”等特点,为黄芪的现代诊疗提供理论依据,以开发更多的药用价值。 展开更多
关键词 黄芪 古代 病-药-量 数据挖掘 用药规律 疮疡 虚劳 汗病 中风
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经皮穴位电刺激对气道狭窄患者硬质支气管镜术后咽喉痛的影响 被引量:1
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作者 利雪阳 吴安石 +2 位作者 昝京伟 刘国凯 任惠龙 《徐州医科大学学报》 2025年第2期84-87,共4页
目的观察经皮穴位电刺激(TEAS)对气道狭窄患者硬质支气管镜术后咽喉痛(POST)的影响。方法选择2024年8—11月择期在硬质支气管镜下治疗气道狭窄的患者60例,男33例,女27例,年龄18~80岁,ASAⅠ—Ⅲ级。采用随机数字表法将患者分为观察组和... 目的观察经皮穴位电刺激(TEAS)对气道狭窄患者硬质支气管镜术后咽喉痛(POST)的影响。方法选择2024年8—11月择期在硬质支气管镜下治疗气道狭窄的患者60例,男33例,女27例,年龄18~80岁,ASAⅠ—Ⅲ级。采用随机数字表法将患者分为观察组和对照组,各30例。观察组于麻醉诱导前30 min在双侧合谷穴和内关穴行TEAS,至患者出手术室前停止;对照组于相同穴位放置电极片,但不进行电刺激。记录硬质支气管镜留置时间、术中丙泊酚和瑞芬太尼用量,记录拔管后1、6、24、48 h POST发生率和评分、声音嘶哑(HOV)发生率,记录POST持续时间和不良反应发生情况。结果与对照组相比,观察组术中瑞芬太尼用量明显减少,术后1、6、24、48 h POST发生率和评分明显降低,POST持续时间明显缩短,恶心呕吐发生率明显降低(P<0.05)。2组术后HOV发生率差异无统计学意义。结论TEAS双侧合谷和内关穴可明显降低硬质支气管镜下气道狭窄患者POST的发生率和咽喉疼痛评分,缩短POST持续时间,减少术中阿片类药物用量,降低恶心呕吐发生率。 展开更多
关键词 经皮穴位电刺激 硬质支气管镜 气道狭窄 术后咽喉痛 阿片类药物
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基于PIgR-CR1介导的“黏膜-肾轴”探析补肾健脾、解毒利咽法防治IgA肾病的研究思路
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作者 李凡 王宏安 +5 位作者 南赫 何鸣宇 崔成姬 王银萍 刘禹彤 张守琳 《中国实验方剂学杂志》 北大核心 2025年第7期237-244,共8页
免疫球蛋白A肾病(IgAN)是世界范围内发病率最高的原发性肾小球肾炎,也是导致我国终末期肾病(ESRD)的主要病因,给社会和家庭带来了沉重的经济负担,中医药在治疗本病上具有一定的优势。中医可将其归属于“虚劳”“血尿”“水肿”等范畴,... 免疫球蛋白A肾病(IgAN)是世界范围内发病率最高的原发性肾小球肾炎,也是导致我国终末期肾病(ESRD)的主要病因,给社会和家庭带来了沉重的经济负担,中医药在治疗本病上具有一定的优势。中医可将其归属于“虚劳”“血尿”“水肿”等范畴,传统认为病位在肾,与肺肝脾等密切相关。而国医大师任继学教授认为“肾虚脾亏是IgAN发病之本,而咽喉是发病之源”,提出“喉肾相关”理论,以补肾健脾、解毒利咽法治疗IgAN,疗效显著。研究表明IgAN与黏膜免疫防御功能密切相关,IgAN患者常因黏膜感染而诱发病情反复发作并逐渐加重,而多聚免疫球蛋白受体(PIgR)是黏膜防御功能的重要组成部分,PIgR缺乏导致IgA分子积聚于黏膜固有层,大量进入血液循环,最终沉积于肾脏引起肾损伤,补体调节蛋白补体受体1型(CR1)存在于红细胞及肾小球上,具有抑制B细胞活化、分化、清除免疫复合物及抑制补体系统过度激活等作用,因此通过PIgR-CR1介导的“黏膜-肾轴”调控机体免疫防御功能将是防治IgAN的重要靶点。该文基于“喉肾相关”理论,探析补肾健脾、解毒利咽法通过调控PIgR-CR1介导的“黏膜-肾轴”进而防治IgAN的作用与分子机制,为中医药基于“喉肾相关”理论防治IgAN提供有效的理论支撑及科学依据。 展开更多
关键词 免疫球蛋白A肾病(IgAN) 黏膜-肾轴 多聚免疫球蛋白受体 补体受体1型(CR1) 补肾健脾 解毒利咽
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