To the Editor:Basal cell carcinoma(BCC)is a malignant tumor originating from the basal cells of the epidermis and is the most common form of skin cancer.In China,the incidence of BCC has risen due to socioeconomic adv...To the Editor:Basal cell carcinoma(BCC)is a malignant tumor originating from the basal cells of the epidermis and is the most common form of skin cancer.In China,the incidence of BCC has risen due to socioeconomic advancements and an aging population.[1]While early diagnosis and treatment typically result in favorable outcomes,0.8–2.0%of patients may progress to locally advanced BCC(laBCC),characterized by lesions≥10 mm in diameter.Traditional treatments,such as surgery or radiotherapy,may be unsuitable for laBCC due to the risk of morbidity,deformity,incomplete tumor removal,and high recurrence rates.展开更多
基金This work was supported by grants from the National Natural Science Foundation of China(Nos.81703145,82003351,82002042,and 82104485)the National Key Research and Development Program of China(No.2023YFC2509000)+3 种基金the Clinical Research Plan of Shanghai Hospital Development Center(No.SHDC22022302)the Shanghai Key Specialty Research Centre Construction Project(Shanghai Municipal Health Commission,No.2023ZZ02018)the Leading Talent Project of Shanghai Municipal Health Commission(No.2022LJ017)the Shanghai Municipal Key Clinical Specialty(No.shslczdzk01002).
文摘To the Editor:Basal cell carcinoma(BCC)is a malignant tumor originating from the basal cells of the epidermis and is the most common form of skin cancer.In China,the incidence of BCC has risen due to socioeconomic advancements and an aging population.[1]While early diagnosis and treatment typically result in favorable outcomes,0.8–2.0%of patients may progress to locally advanced BCC(laBCC),characterized by lesions≥10 mm in diameter.Traditional treatments,such as surgery or radiotherapy,may be unsuitable for laBCC due to the risk of morbidity,deformity,incomplete tumor removal,and high recurrence rates.
