Allylic amines and 1,3-oxazinanes are valuable molecular skeletons in organic synthesis and pharmaceutical industry.A straightforward way to such two types of compounds by solvent-controlled rare-earth metal Lewis aci...Allylic amines and 1,3-oxazinanes are valuable molecular skeletons in organic synthesis and pharmaceutical industry.A straightforward way to such two types of compounds by solvent-controlled rare-earth metal Lewis acid-catalyzed transformations of 2-(hetero)aryl-N-sulfonylazetidines:the ring-opening isomerization of azetidines to allylic amines and the annulation of azetidines with aldehydes to 1,3-oxazinanes are reported.These two reactions feature scalability,low catalyst loading,mild reaction conditions,excellent yields and regioselectivity with demonstrated utility in three-step product transformations to naftifine,abamine and abamine SG.展开更多
Methods for promoting product and reducing energy consumption in a solvent dewaxing device are putforward.Then,the authors mainly discuss about adaptive database,mathematical modeling,mathematical op-timized control a...Methods for promoting product and reducing energy consumption in a solvent dewaxing device are putforward.Then,the authors mainly discuss about adaptive database,mathematical modeling,mathematical op-timized control algorithm,expert optimized control system and intelligent alarming system etc.At last,hard-ware and software of the intelligent optimized control system are introduced.Field test is finally chosen for thisstudy and proved that the intelligent optimized control system is effective.展开更多
Extractive distillation is an effective method for separating azeotropic or close boiling point mixtures by adding a third component.Various technologies for performing the extractive distillation process have been ex...Extractive distillation is an effective method for separating azeotropic or close boiling point mixtures by adding a third component.Various technologies for performing the extractive distillation process have been explored to protect the environment and save resources.This paper focuses on the improvement of these advanced technologies in recent years.Extractive distillation is retrieved and analyzed from the view of phase equilibrium,selection of solvent in extractive distillation,process design,energy conservation,and dynamic control.The quantitative structure–property relationship used in extractive distillation is discussed,and the future development of extractive distillation is proposed to determine how the solvent affects the relative volatility of the separated mixture.In the steady state design,the relationship between the curvature of the residue curve and parameters of the optimal steady state is also highlighted as another field worthy of further study to simplify the distillation process.展开更多
文摘Allylic amines and 1,3-oxazinanes are valuable molecular skeletons in organic synthesis and pharmaceutical industry.A straightforward way to such two types of compounds by solvent-controlled rare-earth metal Lewis acid-catalyzed transformations of 2-(hetero)aryl-N-sulfonylazetidines:the ring-opening isomerization of azetidines to allylic amines and the annulation of azetidines with aldehydes to 1,3-oxazinanes are reported.These two reactions feature scalability,low catalyst loading,mild reaction conditions,excellent yields and regioselectivity with demonstrated utility in three-step product transformations to naftifine,abamine and abamine SG.
基金Supported by the Eighth Five Year plan Research Program(No.85-720-10-21).
文摘Methods for promoting product and reducing energy consumption in a solvent dewaxing device are putforward.Then,the authors mainly discuss about adaptive database,mathematical modeling,mathematical op-timized control algorithm,expert optimized control system and intelligent alarming system etc.At last,hard-ware and software of the intelligent optimized control system are introduced.Field test is finally chosen for thisstudy and proved that the intelligent optimized control system is effective.
基金Supported by the National Natural Science Foundation of China(21676152)
文摘Extractive distillation is an effective method for separating azeotropic or close boiling point mixtures by adding a third component.Various technologies for performing the extractive distillation process have been explored to protect the environment and save resources.This paper focuses on the improvement of these advanced technologies in recent years.Extractive distillation is retrieved and analyzed from the view of phase equilibrium,selection of solvent in extractive distillation,process design,energy conservation,and dynamic control.The quantitative structure–property relationship used in extractive distillation is discussed,and the future development of extractive distillation is proposed to determine how the solvent affects the relative volatility of the separated mixture.In the steady state design,the relationship between the curvature of the residue curve and parameters of the optimal steady state is also highlighted as another field worthy of further study to simplify the distillation process.
