In this study,a straightforward one-step hydrothermal method was successfully utilized to synthesize the solid solution Na_(0.9)Mg_(0.45)Ti_(3.55)O_(8)-Na_(2)Ni_(2)Ti_(6)O_(16)(NNMTO-x),where x denotes the molar perce...In this study,a straightforward one-step hydrothermal method was successfully utilized to synthesize the solid solution Na_(0.9)Mg_(0.45)Ti_(3.55)O_(8)-Na_(2)Ni_(2)Ti_(6)O_(16)(NNMTO-x),where x denotes the molar percentage of Na_(2)Ni_(2)Ti_(6)O_(16)(NNTO)within Na_(0.9)Mg_(0.45)Ti_(3.55)O_(8)(NMTO),with x values of 10,20,30,40,and 50.Both XPS(X-ray Photoelectron Spectroscopy)and EDX(Energy Dispersive X-ray Spectroscopy)analyses unequivocally validated the formation of the NNMTO-x solid solutions.It was observed that when x is below 40,the NNMTO-x solid solution retains the structural characteristics of the original NMTO.However,beyond this threshold,significant alterations in crystal morphology were noted,accompanied by a noticeable decline in photocatalytic activity.Notably,the absorption edge of NNMTO-x(x<40)exhibited a shift towards the visible-light spectrum,thereby substantially broadening the absorption range.The findings highlight that NNMTO-30 possesses the most pronounced photocatalytic activity for the reduction of CO_(2).Specifically,after a 6 h irradiation period,the production rates of CO and CH_(4)were recorded at 42.38 and 1.47μmol/g,respectively.This investigation provides pivotal insights that are instrumental in the advancement of highly efficient and stable photocatalysts tailored for CO_(2)reduction processes.展开更多
In this paper,we consider the maximal positive definite solution of the nonlinear matrix equation.By using the idea of Algorithm 2.1 in ZHANG(2013),a new inversion-free method with a stepsize parameter is proposed to ...In this paper,we consider the maximal positive definite solution of the nonlinear matrix equation.By using the idea of Algorithm 2.1 in ZHANG(2013),a new inversion-free method with a stepsize parameter is proposed to obtain the maximal positive definite solution of nonlinear matrix equation X+A^(*)X|^(-α)A=Q with the case 0<α≤1.Based on this method,a new iterative algorithm is developed,and its convergence proof is given.Finally,two numerical examples are provided to show the effectiveness of the proposed method.展开更多
Strategies for achieving high-energy-density lithium-ion batteries include using high-capacity materials such as high-nickel NCM,increasing the active material content in the electrode by utilizing high-conductivity c...Strategies for achieving high-energy-density lithium-ion batteries include using high-capacity materials such as high-nickel NCM,increasing the active material content in the electrode by utilizing high-conductivity carbon nanotubes(CNT)conductive materials,and electrode thickening.However,these methods are still limited due to the limitation in the capacity of high-nickel NCM,aggregation of CNT conductive materials,and nonuniform material distribution of thick-film electrodes,which ultimately damage the mechanical and electrical integrity of the electrode,leading to a decrease in electrochemical performance.Here,we present an integrated binder-CNT composite dispersion solution to realize a high-solids-content(>77 wt%)slurry for high-mass-loading electrodes and to mitigate the migration of binder and conductive additives.Indeed,the approach reduces solvent usage by approximately 30%and ensures uniform conductive additive-binder domain distribution during electrode manufacturing,resulting in improved coating quality and adhesive strength for high-mass-loading electrodes(>12 mAh cm^(−2)).In terms of various electrode properties,the presented electrode showed low resistance and excellent electrochemical properties despite the low CNT contents of 0.6 wt%compared to the pristine-applied electrode with 0.85 wt%CNT contents.Moreover,our strategy enables faster drying,which increases the coating speed,thereby offering potential energy savings and supporting carbon neutrality in wet-based electrode manufacturing processes.展开更多
TMPRSS2 plays a crucial role in facilitating the entry of both the influenza virus and the SARSCoV-2 coronavirus into host cells.Recent studies have identified a guanine-rich sequence in the proximal promoter region o...TMPRSS2 plays a crucial role in facilitating the entry of both the influenza virus and the SARSCoV-2 coronavirus into host cells.Recent studies have identified a guanine-rich sequence in the proximal promoter region of the TMPRSS2 gene,which can form G-quadruplex structures(TMPRSS2-G4s)that are potential targets for small molecules to inhibit TMPRSS2 expression.However,the structural details of the major TMPRSS2-G4 and its complex with small molecules remain unknown,hindering the development of antiviral drugs targeting TMPRSS2-Gquadruplexes(G4s).This study reports the first high-resolution nuclear magnetic resonance(NMR)solution structure of the major TMPRSS2-G4,which consists of a three-tetrad core parallel-stranded G4.Both 3′and 5′flanking regions form well-defined capping structures stabilized by multiple hydrogen bonds.Importantly,we found that berberine,an antiviral alkaloid,strongly binds to the major TMPRSS2-G4 and determined its binding complex structure with TMPRSS2-G4 at a 2∶1 binding stoichiometry.Each berberine molecule recruits an adjacent flanking residue,forming a coplanar structure superimposed on two outer G-tetrads.Moreover,we demonstrated that the major TMPRSS2-G4 can stably form within a longer deoxyribonucleic acid(DNA)context and be targeted by small molecules to inhibit DNA polymerase activity.Overall,this study provides structural insights into the recognition mechanism of small molecules by the major TMPRSS2-G4 and may facilitate the development of novel antiviral therapeutics targeting TMPRSS2-G4.展开更多
Zn-Mn alloys are regarded as promising biodegradable metals for orthopedic applications owing to their moderate degradation rates and favorable osteogenic properties.However,the presence of a substantial number of sec...Zn-Mn alloys are regarded as promising biodegradable metals for orthopedic applications owing to their moderate degradation rates and favorable osteogenic properties.However,the presence of a substantial number of second-phase particles in Zn-based alloys might induce severe localized degradation via micro-coupling corrosion,thereby compromising the mechanical integrity of the alloy during in vivo tissue regeneration.In this study,high pressure solid solution(HPSS)treatment was conducted at 5 GPa and 380℃ for 1 h to fabricate Zn-0.5 Mn alloys.Microstructural characterization revealed that the HPSS treatment facilitated the formation of a supersaturated solid solution by completely dissolving theζ-MnZn_(13) phase into theα-Zn matrix.The resultant strengthening mechanisms,including supersaturated solid solution strengthening,grain-size strengthening,and dislocation strengthening,collectively enhanced the compressive yield strength(σ_(cys))of the Zn-0.5 Mn alloy to about 183.7 MPa,approximately three times that of the as-cast(AC)Zn-0.5 Mn alloy.Moreover,compared with the AC alloy,the HPSS Zn-0.5 Mn alloy exhibited uniform degradation behavior with a markedly reduced degradation rate.展开更多
In this article,we show the existence,uniqueness and stability of bounded solutions to the following quasilinear problems with mean curvature operator(φ'(x′(t)))′=f(t,x),t≥t_(0),lim_(t→∞)x(t)=ψ_(0),lim_(t→...In this article,we show the existence,uniqueness and stability of bounded solutions to the following quasilinear problems with mean curvature operator(φ'(x′(t)))′=f(t,x),t≥t_(0),lim_(t→∞)x(t)=ψ_(0),lim_(t→∞)x′(t)e^(t)=0,where t_(0) and ψ_(0) are real constants,φ(s)=s/√1−s^(2),s∈R with s∈(−1,1),f:[t_(0),∞)×R→R satisfies the Lipschitz or Osgood-type conditions.展开更多
Circumlunar abort trajectories constitute a vital contingency return strategy during the translunar phase of crewed lunar missions.This paper proposes a methodology for constructing the solution set of the circumlunar...Circumlunar abort trajectories constitute a vital contingency return strategy during the translunar phase of crewed lunar missions.This paper proposes a methodology for constructing the solution set of the circumlunar abort trajectory and leverages its advantageous properties to address the optimization design problem of abort trajectories.Initially,a solution set of all feasible abort trajectories,originating from an abort point on the nominal trajectory and complying with fundamental reentry constraints,is formulated through the introduction of two novel design parameters.Subsequently,the geometric characteristics of the solution set,as well as the distributional properties of key iterative constraint responses,including flight time and velocity increment,are analyzed.Finally,the characteristics exhibited in the solution set are employed to directly identify the design parameters of the abort trajectories with minimum flight time and velocity increment,thereby providing solutions to two distinct types of optimization problems.The simulation results for a variety of nominal trajectories,encompassing the reconstruction and redesign of the Apollo13 abort trajectory,validate the proposed method,demonstrating its ability to directly generate optimal abort trajectories.The method proposed in this paper investigates feasible abort trajectories from a global perspective,providing both a framework and convenience for mission planning and iterative optimization in abort trajectory design.展开更多
The detection of amino acid enantiomers holds significant importance in biomedical,chemical,food,and other fields.Traditional chiral recognition methods using fluorescent probes primarily rely on fluorescence intensit...The detection of amino acid enantiomers holds significant importance in biomedical,chemical,food,and other fields.Traditional chiral recognition methods using fluorescent probes primarily rely on fluorescence intensity changes,which can compromise accuracy and repeatability.In this study,we report a novel fluorescent probe(R)-Z1 that achieves effective enantioselective recognition of chiral amino acids in water by altering emission wavelengths(>60 nm).This water-soluble probe(R)-Z1 exhibits cyan or yellow-green luminescence upon interaction with amino acid enantiomers,enabling reliable chiral detection of 14 natural amino acids.It also allows for the determination of enantiomeric excess through monitoring changes in luminescent color.Additionally,a logic operation with two inputs and three outputs was constructed based on these optical properties.Notably,amino acid enantiomers were successfully detected via dual-channel analysis at both the food and cellular levels.This study provides a new dynamic luminescence-based tool for the accurate sensing and detection of amino acid enantiomers.展开更多
Substrate and nutrient supply are essential for vegetable cultivation in greenhouse.The strategies for plant nutrient supply vary depending on the cultivation methods or substrate dosages employed.With the development...Substrate and nutrient supply are essential for vegetable cultivation in greenhouse.The strategies for plant nutrient supply vary depending on the cultivation methods or substrate dosages employed.With the development of mechanization,wide-row spacing substrate cultivation became an optimize mode of the greenhouse cucumber cultivation,aligning with the trend of intelligent agriculture.To determine the optimal nutrient solution supply amount(NS)and supply frequency(SF)for promoting the integrated growth of cucumber under wide-row spacing substrate cultivation,we explored the effects of substrate supply amount(SS),NS,and SF on cucumber yield,quality,and element utilization efficiency.A five-level quadratic orthogonal rotation combination design with three experimental factors(NS,SF,and SS)was implemented for 23 coupling treatments over three growing seasons,including spring(2022S and 2023S)and autumn(2022A).The technique for order preference by similarity to ideal solution(TOPSIS)combining weights based on game theory was applied to construct cucumber comprehensive growth evaluation model.Single and two experimental factors analyses revealed significant effects of single factors and the coupling of NS-SS,NS-SF and SS-SF on the integrated growth of cucumber for all three growing seasons.For the NS-SF-SS combination,the optimal parameters for comprehensive cucumber growth were determined as follows:levels of^(-1).68 for NS,-0.7 for SF,and^(-1).682 for SS in 2022A;-0.43 for NS,-0.06 for SF,and 0.34 for SS in 2022S;0.3 for NS,-0.02 for SF,and 0.04 for SS in 2023S.Furthermore,for SS ranges of 2.00-3.01,3.01-4.50,4.50-5.99,5.99-7.00(L·plant^(-1)),the corresponding NS and SF intervals maximizing cucumber integrated growth in spring were:0.28-0.30(L·plant^(-1))and 6(times·d^(-1)),0.26-0.30(L·plant^(-1))and 6(times·d^(-1)),0.25-0.30(L·plant^(-1))and 6(times·d^(-1)),0.23-0.30(L·plant^(-1))and 6(times·d^(-1)),respectively.With the same SS,the corresponding NS and SF intervals that maximized cucumber integrated growth in autumn were:0.10(L·plant^(-1))and 8(times·d^(-1)),0.18(L·plant^(-1))and 7(times·d^(-1)),0.30(L·plant^(-1))and 6(times·d^(-1)),0.49(L·plant^(-1))and 5(times·d^(-1)),respectively.The results provide a theoretical basis for solution management,and further in-depth research on cucumber cultivation.展开更多
Strong seismic excitation and fault dislocation are likely to occur simultaneously in high-intensity seismic zones,causing severe damage to tunnels crossing active fault zones.This paper aims to develop a novel analyt...Strong seismic excitation and fault dislocation are likely to occur simultaneously in high-intensity seismic zones,causing severe damage to tunnels crossing active fault zones.This paper aims to develop a novel analytical solution to determine the longitudinal mechanical responses of tunnels subjected to the combined effects of seismic waves and strike-slip faulting.Adopting the elastic springbeam model,the seismic waves are modelled as shear horizontal(SH)waves and the fault dislocation follows an S-shaped pattern;the superposition principle for free-fielddisplacements caused by both effects is assumed.In addition,the transmission and reflectionof seismic waves at the fault-rock geological interface and the tangential contact conditions at the tunnel-rock interface are considered.The analytical model is validated against numerical simulations,confirmingits accuracy in calculating tunnel responses.Moreover,a parametric study is conducted to evaluate the impact of key factors,including fault displacement,fault zone width,fault dip angle,earthquake frequency,rock conditions,tunnel lining stiffness,and tangential contact conditions,on tunnel responses.Compared with each effect alone,the combined effects of seismic waves and strike-slip faulting significantlychange the tunnel deformation and internal forces,leading to increased tunnel responses,especially within the fault zone and near the fault-rock interfaces.Depending on specificparameters,tunnel responses can be classifiedinto seismic-dominated,faulting-dominated,and seismic-faulting coupled responses on the basis of the relative contributions of each effect.The proposed analytical solution can be applied to quickly predict the longitudinal mechanical behaviour of tunnels under such combined effects in engineering applications.展开更多
Doping in thin-film transistors(TFTs) plays a crucial role in tailoring material properties to enhance device performance, making them essential for advanced electronic applications. This study explores the synthesis ...Doping in thin-film transistors(TFTs) plays a crucial role in tailoring material properties to enhance device performance, making them essential for advanced electronic applications. This study explores the synthesis and characterization of TFTs fabricated using nickel(Ni)-doped indium oxide(In_(2)O_(3)) via a wet-chemical approach. The presented work investigates the effect of "Ni" incorporation in In_(2)O_(3) on the structural and electrical transport properties of In_(2)O_(3), revealing that higher "Ni" content decreases the oxygen vacancies, leading to a reduction in leakage current and a forward shift in threshold potential(V_(th)).Experimental findings reveal that Ni In O-based TFTs(with Ni = 0.5%) showcase enhanced electrical performance, achieving mobility of 7.54 cm^(2)/(V·s), an impressive ON/OFF current ratio of ~10^(7), a V_(th) of 6.26 V, reduced interfacial trap states(D_(it)) of 8.23 ×10^(12) cm^(-2) and enhanced biased stress stability. The efficacy of "Ni" incorporation is attributed to the upgraded Lewis acidity, stable Ni-O bond strength, and small ionic radius of Ni. Negative bias illumination stability(NBIS) measurements further indicate that device stability diminishes with shorter light wavelengths, likely due to the activation of oxygen vacancies. These findings validate the solution-processed techniques' potential for future large-scale, low-cost, energy-efficient, and high-performance electronics.展开更多
Sandwich functionally graded(FG)auxetic beams are extensively utilized in aerospace,automotive,and biomedical industries due to their excellent strength-toweight ratio,impact resistance,and tunable mechanical properti...Sandwich functionally graded(FG)auxetic beams are extensively utilized in aerospace,automotive,and biomedical industries due to their excellent strength-toweight ratio,impact resistance,and tunable mechanical properties.The integration of FG materials with auxetic structures enhances their adaptability in advanced engineering applications.However,understanding their dynamic behavior under external excitations is essential for optimal design and structural reliability.Nonlinear interactions in such structures pose significant challenges in vibration analysis,necessitating robust analytical methods.This study presents a closed-form solution for the nonlinear forced vibration analysis of sandwich FG auxetic beams,offering an accurate and efficient method for predicting their dynamic response.The beam consists of two FG face sheets with material properties varying through the thickness and a re-entrant honeycomb auxetic core with an adjustable Poisson's ratio.The governing nonlinear equations of motion are derived using the first-order shear deformation theory(FSDT),the modified Gibson model,and the von Kármán relations,formulated through Hamilton's principle.A closed-form solution is obtained via the Galerkin method and multiple-scale technique.The results demonstrate that FG layers enable control of the overweight and dynamic response amplitude,with positive power law indexes reducing weight.Comparisons with finite element results confirm the accuracy of the proposed formulation.展开更多
In-situ stress is a key parameter for underground mine design and rock stability analysis.The borehole overcoring technique is widely used for in-situ stress measurement,but the rheological recovery deformation of roc...In-situ stress is a key parameter for underground mine design and rock stability analysis.The borehole overcoring technique is widely used for in-situ stress measurement,but the rheological recovery deformation of rocks after stress relief introduces errors.To improve accuracy,this study proposes an in-situ stress solution theory that incorporates time-dependent stress relief effects.Triaxial stepwise loadingunloading rheological tests on granite and siltstone established quantitative relationships between instantaneous elastic recovery and viscoelastic recovery under different stress levels,confirming their impact on measurement accuracy.By integrating a dual-class elastic deformation recovery model,an improved in-situ stress solution theory was derived.Additionally,accounting for the nonlinear characteristics of rock masses,a determination method for time-dependent nonlinear mechanical parameters was proposed.Based on the CSIRO hollow inclusion strain cell,time-dependent strain correction equations and long-term confining pressure calibration equations were formulated.Finally,the proposed theory was successfully applied at one iron mine(736 m depth)in Xinjiang,China,and one coal mine(510 m depth)in Ningxia,China.Compared to classical theory,the calculated mean stress values showed accuracy improvements of 6.0%and 9.4%,respectively,validating the applicability and reliability of the proposed theory.展开更多
Titanium plates with a Ti−O solid solution surface-hardened layer were cold roll-bonded with 304 stainless steel plates with high work hardening rates.The evolution and mechanisms affecting the interfacial bonding str...Titanium plates with a Ti−O solid solution surface-hardened layer were cold roll-bonded with 304 stainless steel plates with high work hardening rates.The evolution and mechanisms affecting the interfacial bonding strength in titanium/stainless steel laminated composites were investigated.Results indicate that the hardened layer reduces the interfacial bonding strength from over 261 MPa to less than 204 MPa.During the cold roll-bonding process,the hardened layer fractures,leading to the formation of multi-scale cracks that are difficult for the stainless steel to fill.This not only hinders the development of an interlocking interface but also leads to the presence of numerous microcracks and hardened blocks along the nearly straight interface,consequently weakening the interfacial bonding strength.In metals with high work hardening rates,the conventional approach of enhancing interface interlocking and improving interfacial bonding strength by using a surface-hardened layer becomes less effective.展开更多
为了客观评价地下空间开发地质适宜性并为评价工作提供一种新思路和参考,提出了一种基于三角模糊数的模糊层次分析法(fuzzy analytic hierarchy process based on triangular fuzzy numbers,FAHP)和优劣解距离法(technique for order pr...为了客观评价地下空间开发地质适宜性并为评价工作提供一种新思路和参考,提出了一种基于三角模糊数的模糊层次分析法(fuzzy analytic hierarchy process based on triangular fuzzy numbers,FAHP)和优劣解距离法(technique for order preference by similarity to ideal solution,TOPSIS)相结合的评价方法。通过地质调查研究构建基于土体工程地质性质、水文地质条件、不良地质作用、地形地貌等影响因素为主的层次分析关系模型。基于专家判别利用FAHP计算各评价因素的权重,以各评价指标层的分级临界值作为典型评价样本,利用TOPSIS法对适宜性等级进行非等分划分,基于区间值优化的TOPSIS法建立最终评价模型,通过ArcGIS的空间分析功能等确定每个评价单元适宜性等级。该方法与传统方法相比一定程度上减少了评价过程中专家评判的过多主观影响,评价过程更倾向于定量化,结果更为客观。利用该方法对无锡市区浅层地下空间开发地质适宜性进行评价,评价结果与实际工程经验相符,证明了该方法的有效性,因此该方法对地下空间开发适宜性评价工作具有一定借鉴意义。展开更多
BACKGROUND Esophageal stricture ranks among the most significant complications following endoscopic submucosal dissection(ESD).Excessive fibrotic repair is a typical pathological feature leading to stenosis after ESD....BACKGROUND Esophageal stricture ranks among the most significant complications following endoscopic submucosal dissection(ESD).Excessive fibrotic repair is a typical pathological feature leading to stenosis after ESD.AIM To examine the effectiveness and underlying mechanism of Kangfuxin solution(KFX)in mitigating excessive fibrotic repair of the esophagus post-ESD.METHODS Pigs received KFX at 0.74 mL/kg/d for 21 days after esophageal full circumferential ESD.Endoscopic examinations occurred on days 7 and 21 post-ESD.In vitro,recombinant transforming growth factor(TGF)-β1(5 ng/mL)induced a fibrotic microenvironment in primary esophageal fibroblasts(pEsF).After 24 hours of KFX treatment(at 1.5%,1%,and 0.5%),expression ofα-smooth muscle actin-2(ACTA2),fibronectin(FN),and type collagen I was assessed.Profibrotic signaling was analyzed,including TGF-β1,Smad2/3,and phosphor-smad2/3(p-Smad2/3).RESULTS Compared to the Control group,the groups treated with KFX and prednisolone exhibited reduced esophageal stenosis,lower weight loss rates,and improved food tolerance 21 d after ESD.After treatment,Masson staining revealed thinner and less dense collagen fibers in the submucosal layer.Additionally,the expression of fibrotic effector molecules was notably inhibited.Mechanistically,KFX downregulated the transduction levels of fibrotic functional molecules such as TGF-β1,Smad2/3,and p-Smad2/3.In vitro,pEsF exposed to TGF-β1-induced fibrotic microenvironment displayed increased fibrotic activity,which was reversed by KFX treatment,leading to reduced activation of ACTA2,FN,and collagen I.The 1.5%KFX treatment group showed decreased expression of p-Smad 2/3 in TGF-β1-activated pEsF.CONCLUSION KFX showed promise as a therapeutic option for post-full circumferential esophageal ESD strictures,potentially by suppressing fibroblast fibrotic activity through modulation of the TGF-β1/Smads signaling pathway.展开更多
As the mining industry continues to expand and international oil prices increase,more rigorous demands are being placed on the design of mining equipment.Given this,there is an urgent need to develop new power-driven ...As the mining industry continues to expand and international oil prices increase,more rigorous demands are being placed on the design of mining equipment.Given this,there is an urgent need to develop new power-driven mining equipment to solve the problems of high energy consumption and insufficient power coupling of current equipment.This study proposed a design of a hybrid power system for underground Load Haul Dump(LHD).The proposed design integrated Quality Function Deployment(QFD)and Theory of Inventive Problem Solving(TRIZ).It identified 7 user requirements and 10 related technical features,formulated 11 innovative design solutions,and ultimately adopting an electric drive hybrid power scheme.This scheme effectively addressesd power transmission coupling problems and improve the efficiency of loaders.A 6 m³hybrid power loader prototype has been developed,which reduces operational energy consumption and advances the electrification and green,low-carbon evolution of mining equipment.展开更多
To address the lack of systematic studies on heavy metal fluorescent probes in typical buffer solutions,this study developed a Fe^(3+)and Cu^(2+)fluorescent probe,DHU‑NP‑4,based on a naphthalimide fluorophore.Comparat...To address the lack of systematic studies on heavy metal fluorescent probes in typical buffer solutions,this study developed a Fe^(3+)and Cu^(2+)fluorescent probe,DHU‑NP‑4,based on a naphthalimide fluorophore.Comparative analysis of the probe's performance in various buffer systems revealed that buffers with high organic content are unsuitable for evaluating such probes.Furthermore,the pH of the solvent system was found to significantly influence the probe's behavior.Under highly acidic conditions(pH≤2),DHU‑NP‑4 exhibited exceptional specificity for Fe^(3+),while in alkaline conditions,it demonstrated high specificity for Cu^(2+).Leveraging these properties,the probe enabled the quantitative detection of Fe^(3+)and Cu^(2+)in solution.展开更多
Tin(Sn)-lead(Pb)mixed halide perovskites have attracted widespread interest due to their wider re-sponse wavelength and lower toxicity than lead halide perovskites,Among the preparation methods,the two-step method mor...Tin(Sn)-lead(Pb)mixed halide perovskites have attracted widespread interest due to their wider re-sponse wavelength and lower toxicity than lead halide perovskites,Among the preparation methods,the two-step method more easily controls the crystallization rate and is suitable for preparing large-area per-ovskite devices.However,the residual low-conductivity iodide layer in the two-step method can affect carrier transport and device stability,and the different crystallization rates of Sn-and Pb-based per-ovskites may result in poor film quality.Therefore,Sn-Pb mixed perovskites are mainly prepared by a one-step method.Herein,a MAPb_(0.5)Sn_(0.5)I_(3)-based self-powered photodetector without a hole transport layer is fabricated by a two-step method.By adjusting the concentration of the ascorbic acid(AA)addi-tive,the final perovskite film exhibited a pure phase without residues,and the optimal device exhibited a high responsivity(0.276 A W^(-1)),large specific detectivity(2.38×10^(12) Jones),and enhanced stability.This enhancement is mainly attributed to the inhibition of Sn2+oxidation,the control of crystal growth,and the sufficient reaction between organic ammonium salts and bottom halides due to the AA-induced pore structure.展开更多
基金Supported by the Doctoral Research Start-up Project of Yuncheng University(YQ-2023067)Project of Shanxi Natural Science Foundation(202303021211189)+1 种基金Fund Program for the Scientific Activities of Selected Returned Overseas Professionals in Shanxi Provinces(20220036)Shanxi ProvinceIntelligent Optoelectronic Sensing Application Technology Innovation Center and Shanxi Province Optoelectronic Information Science and TechnologyLaboratory,Yuncheng University.
文摘In this study,a straightforward one-step hydrothermal method was successfully utilized to synthesize the solid solution Na_(0.9)Mg_(0.45)Ti_(3.55)O_(8)-Na_(2)Ni_(2)Ti_(6)O_(16)(NNMTO-x),where x denotes the molar percentage of Na_(2)Ni_(2)Ti_(6)O_(16)(NNTO)within Na_(0.9)Mg_(0.45)Ti_(3.55)O_(8)(NMTO),with x values of 10,20,30,40,and 50.Both XPS(X-ray Photoelectron Spectroscopy)and EDX(Energy Dispersive X-ray Spectroscopy)analyses unequivocally validated the formation of the NNMTO-x solid solutions.It was observed that when x is below 40,the NNMTO-x solid solution retains the structural characteristics of the original NMTO.However,beyond this threshold,significant alterations in crystal morphology were noted,accompanied by a noticeable decline in photocatalytic activity.Notably,the absorption edge of NNMTO-x(x<40)exhibited a shift towards the visible-light spectrum,thereby substantially broadening the absorption range.The findings highlight that NNMTO-30 possesses the most pronounced photocatalytic activity for the reduction of CO_(2).Specifically,after a 6 h irradiation period,the production rates of CO and CH_(4)were recorded at 42.38 and 1.47μmol/g,respectively.This investigation provides pivotal insights that are instrumental in the advancement of highly efficient and stable photocatalysts tailored for CO_(2)reduction processes.
基金Supported in part by Natural Science Foundation of Guangxi(2023GXNSFAA026246)in part by the Central Government's Guide to Local Science and Technology Development Fund(GuikeZY23055044)in part by the National Natural Science Foundation of China(62363003)。
文摘In this paper,we consider the maximal positive definite solution of the nonlinear matrix equation.By using the idea of Algorithm 2.1 in ZHANG(2013),a new inversion-free method with a stepsize parameter is proposed to obtain the maximal positive definite solution of nonlinear matrix equation X+A^(*)X|^(-α)A=Q with the case 0<α≤1.Based on this method,a new iterative algorithm is developed,and its convergence proof is given.Finally,two numerical examples are provided to show the effectiveness of the proposed method.
基金supported by the National Research Foundation of Korea(NRF)grant funded by the Korea government(MSIT)(No.2022M3H4A6A0103720142)the National Research Council of Science&Technology(NST)grant by the Korea government(MSIT)(No.GTL24011-000)+1 种基金the Technology Innovation Program(RS-2024-00404165)through the Korea Planning&Evaluation Institute of Industrial Technology(KEIT)funded by the Ministry of Trade,Industry&Energy(MOTIE,Korea)supported by the Samsung SDI Co.Ltd.and the Korea Institute of Science and Technology(KIST)institutional program(2E33942,2E3394B)。
文摘Strategies for achieving high-energy-density lithium-ion batteries include using high-capacity materials such as high-nickel NCM,increasing the active material content in the electrode by utilizing high-conductivity carbon nanotubes(CNT)conductive materials,and electrode thickening.However,these methods are still limited due to the limitation in the capacity of high-nickel NCM,aggregation of CNT conductive materials,and nonuniform material distribution of thick-film electrodes,which ultimately damage the mechanical and electrical integrity of the electrode,leading to a decrease in electrochemical performance.Here,we present an integrated binder-CNT composite dispersion solution to realize a high-solids-content(>77 wt%)slurry for high-mass-loading electrodes and to mitigate the migration of binder and conductive additives.Indeed,the approach reduces solvent usage by approximately 30%and ensures uniform conductive additive-binder domain distribution during electrode manufacturing,resulting in improved coating quality and adhesive strength for high-mass-loading electrodes(>12 mAh cm^(−2)).In terms of various electrode properties,the presented electrode showed low resistance and excellent electrochemical properties despite the low CNT contents of 0.6 wt%compared to the pristine-applied electrode with 0.85 wt%CNT contents.Moreover,our strategy enables faster drying,which increases the coating speed,thereby offering potential energy savings and supporting carbon neutrality in wet-based electrode manufacturing processes.
基金supported by the National Natural Science Foundation of China(Nos.82322065,82173707,82204241)the Innovation and Entrepreneurship(Shuangchuang)Program of Jiang-su Province(2024)+3 种基金the Natural Science Foundation of Jiangsu Province(No.BK20221039)the Project Program of State Key Laboratory of Natural Medicines(China Pharmaceutical University,No.SKLNMZZ2024JS12)the Fundamental Research Funds for the Central Universities(No.2632025ZD06)the Scientific Research Foundation for High-level Faculty,China Pharmaceutical University(No.3150020065)。
文摘TMPRSS2 plays a crucial role in facilitating the entry of both the influenza virus and the SARSCoV-2 coronavirus into host cells.Recent studies have identified a guanine-rich sequence in the proximal promoter region of the TMPRSS2 gene,which can form G-quadruplex structures(TMPRSS2-G4s)that are potential targets for small molecules to inhibit TMPRSS2 expression.However,the structural details of the major TMPRSS2-G4 and its complex with small molecules remain unknown,hindering the development of antiviral drugs targeting TMPRSS2-Gquadruplexes(G4s).This study reports the first high-resolution nuclear magnetic resonance(NMR)solution structure of the major TMPRSS2-G4,which consists of a three-tetrad core parallel-stranded G4.Both 3′and 5′flanking regions form well-defined capping structures stabilized by multiple hydrogen bonds.Importantly,we found that berberine,an antiviral alkaloid,strongly binds to the major TMPRSS2-G4 and determined its binding complex structure with TMPRSS2-G4 at a 2∶1 binding stoichiometry.Each berberine molecule recruits an adjacent flanking residue,forming a coplanar structure superimposed on two outer G-tetrads.Moreover,we demonstrated that the major TMPRSS2-G4 can stably form within a longer deoxyribonucleic acid(DNA)context and be targeted by small molecules to inhibit DNA polymerase activity.Overall,this study provides structural insights into the recognition mechanism of small molecules by the major TMPRSS2-G4 and may facilitate the development of novel antiviral therapeutics targeting TMPRSS2-G4.
基金Project(52401064)supported by the National Natural Science Foundation of ChinaProject(24B0172)supported by the Scientific Research Fund of Hunan Provincial Education Department,ChinaProject(XDCX2024Y273)supported by the Postgraduate Scientific Research Innovation Project of Xiangtan University,China。
文摘Zn-Mn alloys are regarded as promising biodegradable metals for orthopedic applications owing to their moderate degradation rates and favorable osteogenic properties.However,the presence of a substantial number of second-phase particles in Zn-based alloys might induce severe localized degradation via micro-coupling corrosion,thereby compromising the mechanical integrity of the alloy during in vivo tissue regeneration.In this study,high pressure solid solution(HPSS)treatment was conducted at 5 GPa and 380℃ for 1 h to fabricate Zn-0.5 Mn alloys.Microstructural characterization revealed that the HPSS treatment facilitated the formation of a supersaturated solid solution by completely dissolving theζ-MnZn_(13) phase into theα-Zn matrix.The resultant strengthening mechanisms,including supersaturated solid solution strengthening,grain-size strengthening,and dislocation strengthening,collectively enhanced the compressive yield strength(σ_(cys))of the Zn-0.5 Mn alloy to about 183.7 MPa,approximately three times that of the as-cast(AC)Zn-0.5 Mn alloy.Moreover,compared with the AC alloy,the HPSS Zn-0.5 Mn alloy exhibited uniform degradation behavior with a markedly reduced degradation rate.
基金Supported by the National Natural Science Foundation of China(Grant Nos.12361040,12061064)the National Science Foundation of Gansu Province(Grant No.22JR5RA264)State Scholarship Fund(Grant No.20230862021).
文摘In this article,we show the existence,uniqueness and stability of bounded solutions to the following quasilinear problems with mean curvature operator(φ'(x′(t)))′=f(t,x),t≥t_(0),lim_(t→∞)x(t)=ψ_(0),lim_(t→∞)x′(t)e^(t)=0,where t_(0) and ψ_(0) are real constants,φ(s)=s/√1−s^(2),s∈R with s∈(−1,1),f:[t_(0),∞)×R→R satisfies the Lipschitz or Osgood-type conditions.
文摘Circumlunar abort trajectories constitute a vital contingency return strategy during the translunar phase of crewed lunar missions.This paper proposes a methodology for constructing the solution set of the circumlunar abort trajectory and leverages its advantageous properties to address the optimization design problem of abort trajectories.Initially,a solution set of all feasible abort trajectories,originating from an abort point on the nominal trajectory and complying with fundamental reentry constraints,is formulated through the introduction of two novel design parameters.Subsequently,the geometric characteristics of the solution set,as well as the distributional properties of key iterative constraint responses,including flight time and velocity increment,are analyzed.Finally,the characteristics exhibited in the solution set are employed to directly identify the design parameters of the abort trajectories with minimum flight time and velocity increment,thereby providing solutions to two distinct types of optimization problems.The simulation results for a variety of nominal trajectories,encompassing the reconstruction and redesign of the Apollo13 abort trajectory,validate the proposed method,demonstrating its ability to directly generate optimal abort trajectories.The method proposed in this paper investigates feasible abort trajectories from a global perspective,providing both a framework and convenience for mission planning and iterative optimization in abort trajectory design.
基金the financial support from the National Natural Science Foundation of China(Nos.22377097,22307036,22074114)Natural Science Foundation of Hubei Province of China(Nos.2020CFB623,2021CFB556)Engineering Research Center of Phosphorus Resources Development and Utilization of Ministry of Education(No.LCX202305)。
文摘The detection of amino acid enantiomers holds significant importance in biomedical,chemical,food,and other fields.Traditional chiral recognition methods using fluorescent probes primarily rely on fluorescence intensity changes,which can compromise accuracy and repeatability.In this study,we report a novel fluorescent probe(R)-Z1 that achieves effective enantioselective recognition of chiral amino acids in water by altering emission wavelengths(>60 nm).This water-soluble probe(R)-Z1 exhibits cyan or yellow-green luminescence upon interaction with amino acid enantiomers,enabling reliable chiral detection of 14 natural amino acids.It also allows for the determination of enantiomeric excess through monitoring changes in luminescent color.Additionally,a logic operation with two inputs and three outputs was constructed based on these optical properties.Notably,amino acid enantiomers were successfully detected via dual-channel analysis at both the food and cellular levels.This study provides a new dynamic luminescence-based tool for the accurate sensing and detection of amino acid enantiomers.
基金supported by the China Agriculture Research System(Grant No.CARS-23-D06)the Key Research and Development Program of Shaanxi Province(Grant Nos.2024NC2-GJHX-29 and 2024NC-ZDCYL-05-08)Shaanxi Agricultural Collaborative Innovation and Extension Alliance Project(Grant No.LMZD202202).
文摘Substrate and nutrient supply are essential for vegetable cultivation in greenhouse.The strategies for plant nutrient supply vary depending on the cultivation methods or substrate dosages employed.With the development of mechanization,wide-row spacing substrate cultivation became an optimize mode of the greenhouse cucumber cultivation,aligning with the trend of intelligent agriculture.To determine the optimal nutrient solution supply amount(NS)and supply frequency(SF)for promoting the integrated growth of cucumber under wide-row spacing substrate cultivation,we explored the effects of substrate supply amount(SS),NS,and SF on cucumber yield,quality,and element utilization efficiency.A five-level quadratic orthogonal rotation combination design with three experimental factors(NS,SF,and SS)was implemented for 23 coupling treatments over three growing seasons,including spring(2022S and 2023S)and autumn(2022A).The technique for order preference by similarity to ideal solution(TOPSIS)combining weights based on game theory was applied to construct cucumber comprehensive growth evaluation model.Single and two experimental factors analyses revealed significant effects of single factors and the coupling of NS-SS,NS-SF and SS-SF on the integrated growth of cucumber for all three growing seasons.For the NS-SF-SS combination,the optimal parameters for comprehensive cucumber growth were determined as follows:levels of^(-1).68 for NS,-0.7 for SF,and^(-1).682 for SS in 2022A;-0.43 for NS,-0.06 for SF,and 0.34 for SS in 2022S;0.3 for NS,-0.02 for SF,and 0.04 for SS in 2023S.Furthermore,for SS ranges of 2.00-3.01,3.01-4.50,4.50-5.99,5.99-7.00(L·plant^(-1)),the corresponding NS and SF intervals maximizing cucumber integrated growth in spring were:0.28-0.30(L·plant^(-1))and 6(times·d^(-1)),0.26-0.30(L·plant^(-1))and 6(times·d^(-1)),0.25-0.30(L·plant^(-1))and 6(times·d^(-1)),0.23-0.30(L·plant^(-1))and 6(times·d^(-1)),respectively.With the same SS,the corresponding NS and SF intervals that maximized cucumber integrated growth in autumn were:0.10(L·plant^(-1))and 8(times·d^(-1)),0.18(L·plant^(-1))and 7(times·d^(-1)),0.30(L·plant^(-1))and 6(times·d^(-1)),0.49(L·plant^(-1))and 5(times·d^(-1)),respectively.The results provide a theoretical basis for solution management,and further in-depth research on cucumber cultivation.
基金supported by the National Natural Science Foundation of China(No.41941018)Shanghai Gaofeng Discipline Construction Funding.
文摘Strong seismic excitation and fault dislocation are likely to occur simultaneously in high-intensity seismic zones,causing severe damage to tunnels crossing active fault zones.This paper aims to develop a novel analytical solution to determine the longitudinal mechanical responses of tunnels subjected to the combined effects of seismic waves and strike-slip faulting.Adopting the elastic springbeam model,the seismic waves are modelled as shear horizontal(SH)waves and the fault dislocation follows an S-shaped pattern;the superposition principle for free-fielddisplacements caused by both effects is assumed.In addition,the transmission and reflectionof seismic waves at the fault-rock geological interface and the tangential contact conditions at the tunnel-rock interface are considered.The analytical model is validated against numerical simulations,confirmingits accuracy in calculating tunnel responses.Moreover,a parametric study is conducted to evaluate the impact of key factors,including fault displacement,fault zone width,fault dip angle,earthquake frequency,rock conditions,tunnel lining stiffness,and tangential contact conditions,on tunnel responses.Compared with each effect alone,the combined effects of seismic waves and strike-slip faulting significantlychange the tunnel deformation and internal forces,leading to increased tunnel responses,especially within the fault zone and near the fault-rock interfaces.Depending on specificparameters,tunnel responses can be classifiedinto seismic-dominated,faulting-dominated,and seismic-faulting coupled responses on the basis of the relative contributions of each effect.The proposed analytical solution can be applied to quickly predict the longitudinal mechanical behaviour of tunnels under such combined effects in engineering applications.
基金funded by the research startup funding of National Research Foundation (NRF) of Korea through the Ministry of Science and ICT 2022R1G1A1009887Part of this study was supported by research start-up funding of Anhui University (S202418001/078)。
文摘Doping in thin-film transistors(TFTs) plays a crucial role in tailoring material properties to enhance device performance, making them essential for advanced electronic applications. This study explores the synthesis and characterization of TFTs fabricated using nickel(Ni)-doped indium oxide(In_(2)O_(3)) via a wet-chemical approach. The presented work investigates the effect of "Ni" incorporation in In_(2)O_(3) on the structural and electrical transport properties of In_(2)O_(3), revealing that higher "Ni" content decreases the oxygen vacancies, leading to a reduction in leakage current and a forward shift in threshold potential(V_(th)).Experimental findings reveal that Ni In O-based TFTs(with Ni = 0.5%) showcase enhanced electrical performance, achieving mobility of 7.54 cm^(2)/(V·s), an impressive ON/OFF current ratio of ~10^(7), a V_(th) of 6.26 V, reduced interfacial trap states(D_(it)) of 8.23 ×10^(12) cm^(-2) and enhanced biased stress stability. The efficacy of "Ni" incorporation is attributed to the upgraded Lewis acidity, stable Ni-O bond strength, and small ionic radius of Ni. Negative bias illumination stability(NBIS) measurements further indicate that device stability diminishes with shorter light wavelengths, likely due to the activation of oxygen vacancies. These findings validate the solution-processed techniques' potential for future large-scale, low-cost, energy-efficient, and high-performance electronics.
基金supported by the National Key R&D Program of China(2023YFA1406200)the National Natural Science Foundation of China(T2521005,12174144,12474009,12174146,and 124B2059)the Special Construction Project Fund for Shan-dong Province Taishan Scholars.
文摘Multifunctional optical responsive materials have grown increasingly pivotal in addressingthe escalating demands of sensing,detection,and anti-counterfeiting applications[1,2].These materials exhibit distinct visible optical variations upon exposure to external stimuli,such as pressure,temperature,light,solvents,pH fluctuations,or mechanical force.Fluorescent sensing and anti-counterfeiting technologies leveraging these optical responses have emerged as highly promising solutions.
文摘Sandwich functionally graded(FG)auxetic beams are extensively utilized in aerospace,automotive,and biomedical industries due to their excellent strength-toweight ratio,impact resistance,and tunable mechanical properties.The integration of FG materials with auxetic structures enhances their adaptability in advanced engineering applications.However,understanding their dynamic behavior under external excitations is essential for optimal design and structural reliability.Nonlinear interactions in such structures pose significant challenges in vibration analysis,necessitating robust analytical methods.This study presents a closed-form solution for the nonlinear forced vibration analysis of sandwich FG auxetic beams,offering an accurate and efficient method for predicting their dynamic response.The beam consists of two FG face sheets with material properties varying through the thickness and a re-entrant honeycomb auxetic core with an adjustable Poisson's ratio.The governing nonlinear equations of motion are derived using the first-order shear deformation theory(FSDT),the modified Gibson model,and the von Kármán relations,formulated through Hamilton's principle.A closed-form solution is obtained via the Galerkin method and multiple-scale technique.The results demonstrate that FG layers enable control of the overweight and dynamic response amplitude,with positive power law indexes reducing weight.Comparisons with finite element results confirm the accuracy of the proposed formulation.
基金supported by the National Science and Technology Major Project of the Ministry of Science and Technology of China(No.2024ZD1700201)the National Natural Science Foundation of China(Nos.U2034206,51974014 and 51574014)+1 种基金the Guangdong Basic and Applied Basic Research Foundation(No.2024A1515011631)the National Key Research and Development Project of China(No.2022YFC3004601)。
文摘In-situ stress is a key parameter for underground mine design and rock stability analysis.The borehole overcoring technique is widely used for in-situ stress measurement,but the rheological recovery deformation of rocks after stress relief introduces errors.To improve accuracy,this study proposes an in-situ stress solution theory that incorporates time-dependent stress relief effects.Triaxial stepwise loadingunloading rheological tests on granite and siltstone established quantitative relationships between instantaneous elastic recovery and viscoelastic recovery under different stress levels,confirming their impact on measurement accuracy.By integrating a dual-class elastic deformation recovery model,an improved in-situ stress solution theory was derived.Additionally,accounting for the nonlinear characteristics of rock masses,a determination method for time-dependent nonlinear mechanical parameters was proposed.Based on the CSIRO hollow inclusion strain cell,time-dependent strain correction equations and long-term confining pressure calibration equations were formulated.Finally,the proposed theory was successfully applied at one iron mine(736 m depth)in Xinjiang,China,and one coal mine(510 m depth)in Ningxia,China.Compared to classical theory,the calculated mean stress values showed accuracy improvements of 6.0%and 9.4%,respectively,validating the applicability and reliability of the proposed theory.
基金supported by the National Key R&D Program of China (No. 2018YFA0707300)the National Natural Science Foundation of China (No. 52374376)the Introduction Plan for High end Foreign Experts, China (No. G2023105001L)。
文摘Titanium plates with a Ti−O solid solution surface-hardened layer were cold roll-bonded with 304 stainless steel plates with high work hardening rates.The evolution and mechanisms affecting the interfacial bonding strength in titanium/stainless steel laminated composites were investigated.Results indicate that the hardened layer reduces the interfacial bonding strength from over 261 MPa to less than 204 MPa.During the cold roll-bonding process,the hardened layer fractures,leading to the formation of multi-scale cracks that are difficult for the stainless steel to fill.This not only hinders the development of an interlocking interface but also leads to the presence of numerous microcracks and hardened blocks along the nearly straight interface,consequently weakening the interfacial bonding strength.In metals with high work hardening rates,the conventional approach of enhancing interface interlocking and improving interfacial bonding strength by using a surface-hardened layer becomes less effective.
文摘为了客观评价地下空间开发地质适宜性并为评价工作提供一种新思路和参考,提出了一种基于三角模糊数的模糊层次分析法(fuzzy analytic hierarchy process based on triangular fuzzy numbers,FAHP)和优劣解距离法(technique for order preference by similarity to ideal solution,TOPSIS)相结合的评价方法。通过地质调查研究构建基于土体工程地质性质、水文地质条件、不良地质作用、地形地貌等影响因素为主的层次分析关系模型。基于专家判别利用FAHP计算各评价因素的权重,以各评价指标层的分级临界值作为典型评价样本,利用TOPSIS法对适宜性等级进行非等分划分,基于区间值优化的TOPSIS法建立最终评价模型,通过ArcGIS的空间分析功能等确定每个评价单元适宜性等级。该方法与传统方法相比一定程度上减少了评价过程中专家评判的过多主观影响,评价过程更倾向于定量化,结果更为客观。利用该方法对无锡市区浅层地下空间开发地质适宜性进行评价,评价结果与实际工程经验相符,证明了该方法的有效性,因此该方法对地下空间开发适宜性评价工作具有一定借鉴意义。
基金Supported by Science and Technology Department of Sichuan Province,No.2020YFS0376National Natural Science Foundation of China,No.81900599Science and Technology Program of Hospital of TCM,Southwest Medical University,No.2022-CXTD-01.
文摘BACKGROUND Esophageal stricture ranks among the most significant complications following endoscopic submucosal dissection(ESD).Excessive fibrotic repair is a typical pathological feature leading to stenosis after ESD.AIM To examine the effectiveness and underlying mechanism of Kangfuxin solution(KFX)in mitigating excessive fibrotic repair of the esophagus post-ESD.METHODS Pigs received KFX at 0.74 mL/kg/d for 21 days after esophageal full circumferential ESD.Endoscopic examinations occurred on days 7 and 21 post-ESD.In vitro,recombinant transforming growth factor(TGF)-β1(5 ng/mL)induced a fibrotic microenvironment in primary esophageal fibroblasts(pEsF).After 24 hours of KFX treatment(at 1.5%,1%,and 0.5%),expression ofα-smooth muscle actin-2(ACTA2),fibronectin(FN),and type collagen I was assessed.Profibrotic signaling was analyzed,including TGF-β1,Smad2/3,and phosphor-smad2/3(p-Smad2/3).RESULTS Compared to the Control group,the groups treated with KFX and prednisolone exhibited reduced esophageal stenosis,lower weight loss rates,and improved food tolerance 21 d after ESD.After treatment,Masson staining revealed thinner and less dense collagen fibers in the submucosal layer.Additionally,the expression of fibrotic effector molecules was notably inhibited.Mechanistically,KFX downregulated the transduction levels of fibrotic functional molecules such as TGF-β1,Smad2/3,and p-Smad2/3.In vitro,pEsF exposed to TGF-β1-induced fibrotic microenvironment displayed increased fibrotic activity,which was reversed by KFX treatment,leading to reduced activation of ACTA2,FN,and collagen I.The 1.5%KFX treatment group showed decreased expression of p-Smad 2/3 in TGF-β1-activated pEsF.CONCLUSION KFX showed promise as a therapeutic option for post-full circumferential esophageal ESD strictures,potentially by suppressing fibroblast fibrotic activity through modulation of the TGF-β1/Smads signaling pathway.
文摘As the mining industry continues to expand and international oil prices increase,more rigorous demands are being placed on the design of mining equipment.Given this,there is an urgent need to develop new power-driven mining equipment to solve the problems of high energy consumption and insufficient power coupling of current equipment.This study proposed a design of a hybrid power system for underground Load Haul Dump(LHD).The proposed design integrated Quality Function Deployment(QFD)and Theory of Inventive Problem Solving(TRIZ).It identified 7 user requirements and 10 related technical features,formulated 11 innovative design solutions,and ultimately adopting an electric drive hybrid power scheme.This scheme effectively addressesd power transmission coupling problems and improve the efficiency of loaders.A 6 m³hybrid power loader prototype has been developed,which reduces operational energy consumption and advances the electrification and green,low-carbon evolution of mining equipment.
文摘To address the lack of systematic studies on heavy metal fluorescent probes in typical buffer solutions,this study developed a Fe^(3+)and Cu^(2+)fluorescent probe,DHU‑NP‑4,based on a naphthalimide fluorophore.Comparative analysis of the probe's performance in various buffer systems revealed that buffers with high organic content are unsuitable for evaluating such probes.Furthermore,the pH of the solvent system was found to significantly influence the probe's behavior.Under highly acidic conditions(pH≤2),DHU‑NP‑4 exhibited exceptional specificity for Fe^(3+),while in alkaline conditions,it demonstrated high specificity for Cu^(2+).Leveraging these properties,the probe enabled the quantitative detection of Fe^(3+)and Cu^(2+)in solution.
基金supported by the National Natural Science Foun-dation of China(Nos.52025028,52332008,52372214,52202273,and U22A20137)the Priority Academic Program Development(PAPD)of Jiangsu Higher Education Institutions.
文摘Tin(Sn)-lead(Pb)mixed halide perovskites have attracted widespread interest due to their wider re-sponse wavelength and lower toxicity than lead halide perovskites,Among the preparation methods,the two-step method more easily controls the crystallization rate and is suitable for preparing large-area per-ovskite devices.However,the residual low-conductivity iodide layer in the two-step method can affect carrier transport and device stability,and the different crystallization rates of Sn-and Pb-based per-ovskites may result in poor film quality.Therefore,Sn-Pb mixed perovskites are mainly prepared by a one-step method.Herein,a MAPb_(0.5)Sn_(0.5)I_(3)-based self-powered photodetector without a hole transport layer is fabricated by a two-step method.By adjusting the concentration of the ascorbic acid(AA)addi-tive,the final perovskite film exhibited a pure phase without residues,and the optimal device exhibited a high responsivity(0.276 A W^(-1)),large specific detectivity(2.38×10^(12) Jones),and enhanced stability.This enhancement is mainly attributed to the inhibition of Sn2+oxidation,the control of crystal growth,and the sufficient reaction between organic ammonium salts and bottom halides due to the AA-induced pore structure.
