Background Quantitative flow ratio(QFR)based lesion selection for percutaneous coronary intervention(PCI)treatment has shown clinical benefits in terms of reduced risk for myocardial infarction and repeat revasculariz...Background Quantitative flow ratio(QFR)based lesion selection for percutaneous coronary intervention(PCI)treatment has shown clinical benefits in terms of reduced risk for myocardial infarction and repeat revascularization.Whether this benefit is consistent across different age groups still needs further investigation.Methods In this prespecified subgroup study of FAVORⅢChina trial,we compared long-term clinical outcomes between QFR-guided and angiography-guided PCI among different age groups among 3825 enrolled subjects.The primary endpoint was major adverse cardiac events(MACEs),a composite of all-cause death,myocardial infarction,and ischemia-driven revascularization.Results Of the 3825 patients,1717(44.9%)were aged≥65 years.At baseline,patients≥65 had higher rates of hypertension,hyperlipidaemia,stroke history(P<0.0001),and peripheral vascular disease(P=0.024)and had higher SYNTAX scores(P=0.0095).Compared with standard angiography guidance,the QFR-guided strategy consistently reduced the 1-year(≥65 years,6.04%vs.9.19%,HR=0.65,95%CI:0.46–0.92;<65 years,5.53%vs.8.43%,HR=0.65,95%CI:0.47–0.91)and 3-year MACE rates in both age groups(≥65 years,11.8%vs.15.2%,HR:0.75,95%CI:0.58–0.98;<65 years,9.5%vs.14.6%,HR=0.63;95%CI:0.49–0.81),without a significant interaction(Pinteraction=0.99).Within the QFR-guided group,the 3-year MACE rate in patients with deferred vessels was numerically greater in patients aged≥65 years than in those aged<65 years(8.3%vs.3.0%,P=0.10).Conclusions Although with higher rate of comorbidities and more complex coronary anatomy,the long-term benefit of the QFR-guided PCI strategy remained consistent in patients≥65 years,compared with those<65 years.展开更多
Purpose: To explore the interventional effects of campus psychodrama on improving the interpersonal trust among college students. Methods: 16 college students with low levels of interpersonal trust were selected to co...Purpose: To explore the interventional effects of campus psychodrama on improving the interpersonal trust among college students. Methods: 16 college students with low levels of interpersonal trust were selected to conduct 5 sessions of psychodrama therapy. Results: The subject group has gone through stages of ice breaking, performance, and sharing. Through group counseling with psychodrama, the social avoidance and distressful behaviors of the subjects have been alleviated, and their levels of interpersonal trust demonstrated notable change. Conclusion: Campus psychodrama is an effective group counseling approach for improving college students’ interpersonal trust.展开更多
Objective: Stroke is perceived as a serious illness although it is preventable, and lifestyle alterations can be made to reduce its risk. Improvement of stroke care should be achieved through awareness of public, espe...Objective: Stroke is perceived as a serious illness although it is preventable, and lifestyle alterations can be made to reduce its risk. Improvement of stroke care should be achieved through awareness of public, especially through high-risk group. Henceforth, the aim of this study was to evaluate the effect of nursing intervention on improving awareness of high-risk people about stroke prevention. Methods: A quasi-experimental design was used to carry out this study, where a purposive sample of 80 adult patients at high risk for stroke were enrolled while they were attending the out-patient clinics of Zagazig University Hospitals for follow-up treatment;they were divided into two groups: case (40 patients) and control (40 patients). An interview questionnaire was used to assess patients’ knowledge regarding warning signs, risk factors, and immediate treatment;attitude;and their practice for prevention for stroke at pretest and posttest. Results: The study revealed the poor level of knowledge, bad level of preventive behavior, and negative attitude regarding stroke prevention at pre-intervention. However, after intervention, the high-risk people had fair level of knowledge with moderate practice for stroke prevention and positive attitude, with statistically significant difference between pre-post intervention and between the case and control groups. Conclusions: The study revealed that the nursing intervention seemed to change the knowledge, practice, and attitude of subjects regarding stroke prevention. This, in turn, implies that awareness of prevention of stroke and high-risk factor control could be important to reduce the burden of stroke in Egypt. Thus, further research on a larger scale is required to improve population knowledge and behavior for stroke prevention and control.展开更多
There have been an increasing number of studies on climate change and population health over the past 20 years,with most focusing on health risk assessment,targeting different locations and populations with various di...There have been an increasing number of studies on climate change and population health over the past 20 years,with most focusing on health risk assessment,targeting different locations and populations with various diseases[1−2].While these studies have provided the necessary epidemiological evidence for health authorities in policymaking,it is time to develop and implement tailored health interventions to protect the health and well-being of communities,and particularly that of vulnerable groups.展开更多
Objective: To investigate the effect of group psychological intervention on oxidative stress, apoptosis and inflammatory response in patients with schizophrenia. Methods: A total of 80 patients with schizophrenia who ...Objective: To investigate the effect of group psychological intervention on oxidative stress, apoptosis and inflammatory response in patients with schizophrenia. Methods: A total of 80 patients with schizophrenia who received hospitalization in the hospital between September 2014 and October 2016 were collected and divided into control group (n=40) and observation group (n=40) according to the random number table method. Control group received routine clinical intervention, the observation group received group psychological intervention on the basis of conventional intervention, and the differences in serum contents of oxidative stress indicators, apoptosis molecules and inflammatory factors were compared between the two groups of patients before and after intervention. Results: Before intervention, the differences in serum levels of oxidative stress indexes, apoptosis molecules and inflammatory factors were not statistically significant between the two groups of patients. After intervention, serum SOD and bcl-2 levels of both groups of patients were higher than those before intervention while MDA, bax, Caspace-3, Fas, IL-1β, IL-6 and TNF-α levels were lower than those before intervention, and serum SOD and bcl-2 levels of observation group were higher than those of control group while MDA, bax, Caspace-3, Fas, IL-1β, IL-6 and TNF-α levels were lower than those of control group. Conclusion: Group psychological intervention can effectively inhibit the systemic oxidative stress and inflammatory response, and reduce the process of apoptosis in patients with schizophrenia.展开更多
ADHD is a broad psychiatric disorder that affects children of normal or near-normal intelligence.It is character-ized by inattention,hyperactivity,and age-inappropriate impulsivity,and it is often accompanied by learn...ADHD is a broad psychiatric disorder that affects children of normal or near-normal intelligence.It is character-ized by inattention,hyperactivity,and age-inappropriate impulsivity,and it is often accompanied by learning dif-ficulties,behavioral,emotional,and interpersonal problems.On the other hand,hyperactive tendencies in children with ADHD exhibit ADHD-like behaviors such as lack of self-control,inattention,hyperactivity,and emotional impulsivity.However,because their symptoms are less severe,they do not meet the diagnostic criteria for ADHD but are ADHD or at risk of developing ADHD.The purpose of this study is to alleviate and reduce children’s hyperactivity symptoms by investigating the current situation of the children studied,and systemati-cally intervening and educating children with ADHD through psychological group intervention.Research data shows that ADHD is most commonly diagnosed in school-age children,and in 70%–80%of children with ADHD,symptoms persist into adolescence and 30%into adulthood.Through the use of group psychological intervention in the experiment,the prevalence rate of children with hyperactivity disorder tendency has been effectively reduced.This shows that group psychological intervention training has a significant effect on improving hyper-activity symptoms in children with ADHD tendency.展开更多
Objective:To evaluate and analyze the clinical effect of group intervention combined with massage nursing in patients with lymphedema.Methods:The time span of this study was selected from October 2017 to December 2020...Objective:To evaluate and analyze the clinical effect of group intervention combined with massage nursing in patients with lymphedema.Methods:The time span of this study was selected from October 2017 to December 2020.A total of 496 patients with lymphedema after breast cancer surgery were included.They were divided into study group and control group according to the difference of nursing intervention scheme.The control group was given basic nursing,and the study group was given Satya group intervention combined with massage nursing.The indicators of the two groups were compared and analyzed.Results:Compared with the two groups at different time points,the study group had more advantages(P<0.05).Compared with the recurrence rate of lymphedema in the two groups,the study group had more advantages(P<0.05);Compared with the sads score and SES score after nursing intervention,the study group had more advantages(P<0.05).Conclusion:The clinical effect of group intervention combined with massage nursing in patients with lymphedema is significant,which can be promoted in all levels of medical institutions.展开更多
Objective:The purpose of this study was to evaluate the effectiveness of post-traumatic growth(PTG)model-based intervention to improve positive psychological traits in Chinese breast cancer patients.Design:A randomize...Objective:The purpose of this study was to evaluate the effectiveness of post-traumatic growth(PTG)model-based intervention to improve positive psychological traits in Chinese breast cancer patients.Design:A randomized control trial of a psychological group intervention based on PTG model.Methods:The Clinical Trial was registered on 17 August 2019 at Chinese Clinical Trials.gov with Registration number ChiCTR1900025264.A total of 92 patients with breast cancer were recruited.The participants were randomly assigned to the experimental group(n=46)and the control group(n=46).A six-session psychological group intervention based on PTG model was implemented in the experimental group,and a six-session health education was implemented in the control group.The outcomes weremeasured at baseline(pre-intervention),3 weeks,6 weeks after the intervention.The primary outcome was posttraumatic growth assessed by the Chinese version of the Post-Traumatic Growth Inventory(PTGI);Secondary outcomes included psychological resilience,family resilience,rumination,and self-disclosure.Results:A total of 87 patients with breast cancer completed this study,including 44 patients in the experimental group and 43 patients in the control group.There was no significant difference in baseline data of breast cancer patients between the two groups except for the treatment regimen(p>0.05).The two groups were compared after the intervention;the interaction effects between the total scores of posttraumatic growth,family resilience,and self-disclosure and the time term were statistically significant(p<0.05),indicating that the trend of change in total scores of post-traumatic growth,family resilience,and self-disclosure differed between the experimental and control groups over time,and the scores improved in the experimental group were significantly higher than those in the control group.The comparison of psychological resilience and total score of rumination at each time point was statistically significant(p<0.05),indicating that group intervention based on the PTG model could improve the psychological recovery ability and rumination level of the experimental group.Conclusion:The psychological group intervention based on the PTG model significantly improved post-traumatic growth,family resilience,and self-disclosure in patients with breast cancer.However,the impact on psychological resilience and rumination was relatively small.Long-term intervention is needed to further test the effect of the PTG model on psychological resilience and rumination.展开更多
Objective: taking hypertension as the object and nursing as the research direction to analyze the effect of nursing intervention in the mode of knowledge, belief and behavior. Methods: during the study period from sep...Objective: taking hypertension as the object and nursing as the research direction to analyze the effect of nursing intervention in the mode of knowledge, belief and behavior. Methods: during the study period from sep., 2021 to June, 2022, a prospective nursing study of hypertension was selected, and 200 patients who cooperated with the study were selected to carry out the study, and assisted them to complete random grouping with model nursing interventions. Results: comparing the observation group and the control group, the quality of life score was used as the index, and the former was higher (P < 0.05);the medical compliance behavior score was used as the index, and the former was higher (P < 0.05);the former is larger (P<0.05). Conclusion: after the diagnosis of hypertension, comprehensive assessment of the patients condition and early implementation of the nursing intervention of the knowledge, belief, and behavior model can improve the quality of life, improve medical compliance behavior, and make patients satisfied.展开更多
Background:Despite highly effective vaccines against SARS-CoV-2,COVID-19 vaccine hesitancy persisted in some populations in England during the pandemic,with rates and motivations for hesitancy varying by demographic g...Background:Despite highly effective vaccines against SARS-CoV-2,COVID-19 vaccine hesitancy persisted in some populations in England during the pandemic,with rates and motivations for hesitancy varying by demographic group.Addressing the drivers of vaccine hesitancy through targeted interventions in hesitant groups is a public health priority for better and more rapid control of disease spread.We aimed to characterise the determinants and subtypes of vaccine hesitancy and identify more persistent forms of hesitancy via analysis of vaccine uptake in a large cross-sectional cohort with linked National Health Service(NHS)data.展开更多
文摘Background Quantitative flow ratio(QFR)based lesion selection for percutaneous coronary intervention(PCI)treatment has shown clinical benefits in terms of reduced risk for myocardial infarction and repeat revascularization.Whether this benefit is consistent across different age groups still needs further investigation.Methods In this prespecified subgroup study of FAVORⅢChina trial,we compared long-term clinical outcomes between QFR-guided and angiography-guided PCI among different age groups among 3825 enrolled subjects.The primary endpoint was major adverse cardiac events(MACEs),a composite of all-cause death,myocardial infarction,and ischemia-driven revascularization.Results Of the 3825 patients,1717(44.9%)were aged≥65 years.At baseline,patients≥65 had higher rates of hypertension,hyperlipidaemia,stroke history(P<0.0001),and peripheral vascular disease(P=0.024)and had higher SYNTAX scores(P=0.0095).Compared with standard angiography guidance,the QFR-guided strategy consistently reduced the 1-year(≥65 years,6.04%vs.9.19%,HR=0.65,95%CI:0.46–0.92;<65 years,5.53%vs.8.43%,HR=0.65,95%CI:0.47–0.91)and 3-year MACE rates in both age groups(≥65 years,11.8%vs.15.2%,HR:0.75,95%CI:0.58–0.98;<65 years,9.5%vs.14.6%,HR=0.63;95%CI:0.49–0.81),without a significant interaction(Pinteraction=0.99).Within the QFR-guided group,the 3-year MACE rate in patients with deferred vessels was numerically greater in patients aged≥65 years than in those aged<65 years(8.3%vs.3.0%,P=0.10).Conclusions Although with higher rate of comorbidities and more complex coronary anatomy,the long-term benefit of the QFR-guided PCI strategy remained consistent in patients≥65 years,compared with those<65 years.
文摘Purpose: To explore the interventional effects of campus psychodrama on improving the interpersonal trust among college students. Methods: 16 college students with low levels of interpersonal trust were selected to conduct 5 sessions of psychodrama therapy. Results: The subject group has gone through stages of ice breaking, performance, and sharing. Through group counseling with psychodrama, the social avoidance and distressful behaviors of the subjects have been alleviated, and their levels of interpersonal trust demonstrated notable change. Conclusion: Campus psychodrama is an effective group counseling approach for improving college students’ interpersonal trust.
文摘Objective: Stroke is perceived as a serious illness although it is preventable, and lifestyle alterations can be made to reduce its risk. Improvement of stroke care should be achieved through awareness of public, especially through high-risk group. Henceforth, the aim of this study was to evaluate the effect of nursing intervention on improving awareness of high-risk people about stroke prevention. Methods: A quasi-experimental design was used to carry out this study, where a purposive sample of 80 adult patients at high risk for stroke were enrolled while they were attending the out-patient clinics of Zagazig University Hospitals for follow-up treatment;they were divided into two groups: case (40 patients) and control (40 patients). An interview questionnaire was used to assess patients’ knowledge regarding warning signs, risk factors, and immediate treatment;attitude;and their practice for prevention for stroke at pretest and posttest. Results: The study revealed the poor level of knowledge, bad level of preventive behavior, and negative attitude regarding stroke prevention at pre-intervention. However, after intervention, the high-risk people had fair level of knowledge with moderate practice for stroke prevention and positive attitude, with statistically significant difference between pre-post intervention and between the case and control groups. Conclusions: The study revealed that the nursing intervention seemed to change the knowledge, practice, and attitude of subjects regarding stroke prevention. This, in turn, implies that awareness of prevention of stroke and high-risk factor control could be important to reduce the burden of stroke in Egypt. Thus, further research on a larger scale is required to improve population knowledge and behavior for stroke prevention and control.
文摘There have been an increasing number of studies on climate change and population health over the past 20 years,with most focusing on health risk assessment,targeting different locations and populations with various diseases[1−2].While these studies have provided the necessary epidemiological evidence for health authorities in policymaking,it is time to develop and implement tailored health interventions to protect the health and well-being of communities,and particularly that of vulnerable groups.
文摘Objective: To investigate the effect of group psychological intervention on oxidative stress, apoptosis and inflammatory response in patients with schizophrenia. Methods: A total of 80 patients with schizophrenia who received hospitalization in the hospital between September 2014 and October 2016 were collected and divided into control group (n=40) and observation group (n=40) according to the random number table method. Control group received routine clinical intervention, the observation group received group psychological intervention on the basis of conventional intervention, and the differences in serum contents of oxidative stress indicators, apoptosis molecules and inflammatory factors were compared between the two groups of patients before and after intervention. Results: Before intervention, the differences in serum levels of oxidative stress indexes, apoptosis molecules and inflammatory factors were not statistically significant between the two groups of patients. After intervention, serum SOD and bcl-2 levels of both groups of patients were higher than those before intervention while MDA, bax, Caspace-3, Fas, IL-1β, IL-6 and TNF-α levels were lower than those before intervention, and serum SOD and bcl-2 levels of observation group were higher than those of control group while MDA, bax, Caspace-3, Fas, IL-1β, IL-6 and TNF-α levels were lower than those of control group. Conclusion: Group psychological intervention can effectively inhibit the systemic oxidative stress and inflammatory response, and reduce the process of apoptosis in patients with schizophrenia.
文摘ADHD is a broad psychiatric disorder that affects children of normal or near-normal intelligence.It is character-ized by inattention,hyperactivity,and age-inappropriate impulsivity,and it is often accompanied by learning dif-ficulties,behavioral,emotional,and interpersonal problems.On the other hand,hyperactive tendencies in children with ADHD exhibit ADHD-like behaviors such as lack of self-control,inattention,hyperactivity,and emotional impulsivity.However,because their symptoms are less severe,they do not meet the diagnostic criteria for ADHD but are ADHD or at risk of developing ADHD.The purpose of this study is to alleviate and reduce children’s hyperactivity symptoms by investigating the current situation of the children studied,and systemati-cally intervening and educating children with ADHD through psychological group intervention.Research data shows that ADHD is most commonly diagnosed in school-age children,and in 70%–80%of children with ADHD,symptoms persist into adolescence and 30%into adulthood.Through the use of group psychological intervention in the experiment,the prevalence rate of children with hyperactivity disorder tendency has been effectively reduced.This shows that group psychological intervention training has a significant effect on improving hyper-activity symptoms in children with ADHD tendency.
文摘Objective:To evaluate and analyze the clinical effect of group intervention combined with massage nursing in patients with lymphedema.Methods:The time span of this study was selected from October 2017 to December 2020.A total of 496 patients with lymphedema after breast cancer surgery were included.They were divided into study group and control group according to the difference of nursing intervention scheme.The control group was given basic nursing,and the study group was given Satya group intervention combined with massage nursing.The indicators of the two groups were compared and analyzed.Results:Compared with the two groups at different time points,the study group had more advantages(P<0.05).Compared with the recurrence rate of lymphedema in the two groups,the study group had more advantages(P<0.05);Compared with the sads score and SES score after nursing intervention,the study group had more advantages(P<0.05).Conclusion:The clinical effect of group intervention combined with massage nursing in patients with lymphedema is significant,which can be promoted in all levels of medical institutions.
基金Funding from the 2018 Postgraduate Research&Practice Innovation Program of Jiangsu Province is gratefully acknowledged(SJCX18_0082).
文摘Objective:The purpose of this study was to evaluate the effectiveness of post-traumatic growth(PTG)model-based intervention to improve positive psychological traits in Chinese breast cancer patients.Design:A randomized control trial of a psychological group intervention based on PTG model.Methods:The Clinical Trial was registered on 17 August 2019 at Chinese Clinical Trials.gov with Registration number ChiCTR1900025264.A total of 92 patients with breast cancer were recruited.The participants were randomly assigned to the experimental group(n=46)and the control group(n=46).A six-session psychological group intervention based on PTG model was implemented in the experimental group,and a six-session health education was implemented in the control group.The outcomes weremeasured at baseline(pre-intervention),3 weeks,6 weeks after the intervention.The primary outcome was posttraumatic growth assessed by the Chinese version of the Post-Traumatic Growth Inventory(PTGI);Secondary outcomes included psychological resilience,family resilience,rumination,and self-disclosure.Results:A total of 87 patients with breast cancer completed this study,including 44 patients in the experimental group and 43 patients in the control group.There was no significant difference in baseline data of breast cancer patients between the two groups except for the treatment regimen(p>0.05).The two groups were compared after the intervention;the interaction effects between the total scores of posttraumatic growth,family resilience,and self-disclosure and the time term were statistically significant(p<0.05),indicating that the trend of change in total scores of post-traumatic growth,family resilience,and self-disclosure differed between the experimental and control groups over time,and the scores improved in the experimental group were significantly higher than those in the control group.The comparison of psychological resilience and total score of rumination at each time point was statistically significant(p<0.05),indicating that group intervention based on the PTG model could improve the psychological recovery ability and rumination level of the experimental group.Conclusion:The psychological group intervention based on the PTG model significantly improved post-traumatic growth,family resilience,and self-disclosure in patients with breast cancer.However,the impact on psychological resilience and rumination was relatively small.Long-term intervention is needed to further test the effect of the PTG model on psychological resilience and rumination.
文摘Objective: taking hypertension as the object and nursing as the research direction to analyze the effect of nursing intervention in the mode of knowledge, belief and behavior. Methods: during the study period from sep., 2021 to June, 2022, a prospective nursing study of hypertension was selected, and 200 patients who cooperated with the study were selected to carry out the study, and assisted them to complete random grouping with model nursing interventions. Results: comparing the observation group and the control group, the quality of life score was used as the index, and the former was higher (P < 0.05);the medical compliance behavior score was used as the index, and the former was higher (P < 0.05);the former is larger (P<0.05). Conclusion: after the diagnosis of hypertension, comprehensive assessment of the patients condition and early implementation of the nursing intervention of the knowledge, belief, and behavior model can improve the quality of life, improve medical compliance behavior, and make patients satisfied.
文摘Background:Despite highly effective vaccines against SARS-CoV-2,COVID-19 vaccine hesitancy persisted in some populations in England during the pandemic,with rates and motivations for hesitancy varying by demographic group.Addressing the drivers of vaccine hesitancy through targeted interventions in hesitant groups is a public health priority for better and more rapid control of disease spread.We aimed to characterise the determinants and subtypes of vaccine hesitancy and identify more persistent forms of hesitancy via analysis of vaccine uptake in a large cross-sectional cohort with linked National Health Service(NHS)data.
