In this study,a straightforward one-step hydrothermal method was successfully utilized to synthesize the solid solution Na_(0.9)Mg_(0.45)Ti_(3.55)O_(8)-Na_(2)Ni_(2)Ti_(6)O_(16)(NNMTO-x),where x denotes the molar perce...In this study,a straightforward one-step hydrothermal method was successfully utilized to synthesize the solid solution Na_(0.9)Mg_(0.45)Ti_(3.55)O_(8)-Na_(2)Ni_(2)Ti_(6)O_(16)(NNMTO-x),where x denotes the molar percentage of Na_(2)Ni_(2)Ti_(6)O_(16)(NNTO)within Na_(0.9)Mg_(0.45)Ti_(3.55)O_(8)(NMTO),with x values of 10,20,30,40,and 50.Both XPS(X-ray Photoelectron Spectroscopy)and EDX(Energy Dispersive X-ray Spectroscopy)analyses unequivocally validated the formation of the NNMTO-x solid solutions.It was observed that when x is below 40,the NNMTO-x solid solution retains the structural characteristics of the original NMTO.However,beyond this threshold,significant alterations in crystal morphology were noted,accompanied by a noticeable decline in photocatalytic activity.Notably,the absorption edge of NNMTO-x(x<40)exhibited a shift towards the visible-light spectrum,thereby substantially broadening the absorption range.The findings highlight that NNMTO-30 possesses the most pronounced photocatalytic activity for the reduction of CO_(2).Specifically,after a 6 h irradiation period,the production rates of CO and CH_(4)were recorded at 42.38 and 1.47μmol/g,respectively.This investigation provides pivotal insights that are instrumental in the advancement of highly efficient and stable photocatalysts tailored for CO_(2)reduction processes.展开更多
Adult neurogenesis continuously produces new neurons critical for cognitive plasticity in adult rodents.While it is known transforming growth factor-βsignaling is important in embryonic neurogenesis,its role in postn...Adult neurogenesis continuously produces new neurons critical for cognitive plasticity in adult rodents.While it is known transforming growth factor-βsignaling is important in embryonic neurogenesis,its role in postnatal neurogenesis remains unclear.In this study,to define the precise role of transforming growth factor-βsignaling in postnatal neurogenesis at distinct stages of the neurogenic cascade both in vitro and in vivo,we developed two novel inducible and cell type-specific mouse models to specifically silence transforming growth factor-βsignaling in neural stem cells in(mGFAPcre-ALK5fl/fl-Ai9)or immature neuroblasts in(DCXcreERT2-ALK5fl/fl-Ai9).Our data showed that exogenous transforming growth factor-βtreatment led to inhibition of the proliferation of primary neural stem cells while stimulating their migration.These effects were abolished in activin-like kinase 5(ALK5)knockout primary neural stem cells.Consistent with this,inhibition of transforming growth factor-βsignaling with SB-431542 in wild-type neural stem cells stimulated proliferation while inhibited the migration of neural stem cells.Interestingly,deletion of transforming growth factor-βreceptor in neural stem cells in vivo inhibited the migration of postnatal born neurons in mGFAPcre-ALK5fl/fl-Ai9 mice,while abolishment of transforming growth factor-βsignaling in immature neuroblasts in DCXcreERT2-ALK5fl/fl-Ai9 mice did not affect the migration of these cells in the hippocampus.In summary,our data supports a dual role of transforming growth factor-βsignaling in the proliferation and migration of neural stem cells in vitro.Moreover,our data provides novel insights on cell type-specific-dependent requirements of transforming growth factor-βsignaling on neural stem cell proliferation and migration in vivo.展开更多
Substrate and nutrient supply are essential for vegetable cultivation in greenhouse.The strategies for plant nutrient supply vary depending on the cultivation methods or substrate dosages employed.With the development...Substrate and nutrient supply are essential for vegetable cultivation in greenhouse.The strategies for plant nutrient supply vary depending on the cultivation methods or substrate dosages employed.With the development of mechanization,wide-row spacing substrate cultivation became an optimize mode of the greenhouse cucumber cultivation,aligning with the trend of intelligent agriculture.To determine the optimal nutrient solution supply amount(NS)and supply frequency(SF)for promoting the integrated growth of cucumber under wide-row spacing substrate cultivation,we explored the effects of substrate supply amount(SS),NS,and SF on cucumber yield,quality,and element utilization efficiency.A five-level quadratic orthogonal rotation combination design with three experimental factors(NS,SF,and SS)was implemented for 23 coupling treatments over three growing seasons,including spring(2022S and 2023S)and autumn(2022A).The technique for order preference by similarity to ideal solution(TOPSIS)combining weights based on game theory was applied to construct cucumber comprehensive growth evaluation model.Single and two experimental factors analyses revealed significant effects of single factors and the coupling of NS-SS,NS-SF and SS-SF on the integrated growth of cucumber for all three growing seasons.For the NS-SF-SS combination,the optimal parameters for comprehensive cucumber growth were determined as follows:levels of^(-1).68 for NS,-0.7 for SF,and^(-1).682 for SS in 2022A;-0.43 for NS,-0.06 for SF,and 0.34 for SS in 2022S;0.3 for NS,-0.02 for SF,and 0.04 for SS in 2023S.Furthermore,for SS ranges of 2.00-3.01,3.01-4.50,4.50-5.99,5.99-7.00(L·plant^(-1)),the corresponding NS and SF intervals maximizing cucumber integrated growth in spring were:0.28-0.30(L·plant^(-1))and 6(times·d^(-1)),0.26-0.30(L·plant^(-1))and 6(times·d^(-1)),0.25-0.30(L·plant^(-1))and 6(times·d^(-1)),0.23-0.30(L·plant^(-1))and 6(times·d^(-1)),respectively.With the same SS,the corresponding NS and SF intervals that maximized cucumber integrated growth in autumn were:0.10(L·plant^(-1))and 8(times·d^(-1)),0.18(L·plant^(-1))and 7(times·d^(-1)),0.30(L·plant^(-1))and 6(times·d^(-1)),0.49(L·plant^(-1))and 5(times·d^(-1)),respectively.The results provide a theoretical basis for solution management,and further in-depth research on cucumber cultivation.展开更多
In this paper we use Böcklund transformation to construct soliton solutions for a coupled KdV system.This system was first proposed by Wang in 2010.First we generalize the well-known Bäcklund transformation ...In this paper we use Böcklund transformation to construct soliton solutions for a coupled KdV system.This system was first proposed by Wang in 2010.First we generalize the well-known Bäcklund transformation for the KdV equation to such coupled KdV system.Then from a trivial seed solution,we construct soliton solutions.We also give a nonlinear superposition formula,which allows us to generate multi-soliton solutions.展开更多
Titanium plates with a Ti−O solid solution surface-hardened layer were cold roll-bonded with 304 stainless steel plates with high work hardening rates.The evolution and mechanisms affecting the interfacial bonding str...Titanium plates with a Ti−O solid solution surface-hardened layer were cold roll-bonded with 304 stainless steel plates with high work hardening rates.The evolution and mechanisms affecting the interfacial bonding strength in titanium/stainless steel laminated composites were investigated.Results indicate that the hardened layer reduces the interfacial bonding strength from over 261 MPa to less than 204 MPa.During the cold roll-bonding process,the hardened layer fractures,leading to the formation of multi-scale cracks that are difficult for the stainless steel to fill.This not only hinders the development of an interlocking interface but also leads to the presence of numerous microcracks and hardened blocks along the nearly straight interface,consequently weakening the interfacial bonding strength.In metals with high work hardening rates,the conventional approach of enhancing interface interlocking and improving interfacial bonding strength by using a surface-hardened layer becomes less effective.展开更多
OBJECTIVE To investigate the effect and the mechanisms of realgar transforming solution(RTS)on down-regulating over activated ras.METHODS we used the optimizing technical processes to obtain the RTS,and eval⁃uate the ...OBJECTIVE To investigate the effect and the mechanisms of realgar transforming solution(RTS)on down-regulating over activated ras.METHODS we used the optimizing technical processes to obtain the RTS,and eval⁃uate the mechanisms of RTS on down-regulating overactivated ras in Caenorhabditis elegans.RESULTS We found that the mRNA level of let60 and lin45 significantly decreased following exposure to RTS,but mRNA levels of mpk1 were not statistically significant in let60/ras(gf)mutant.RTS together with sorafenib(RAF inhibitors)significantly enhanced the activity of RTS on down-regulating overactivated ras more than RTS only,but 50μmol·L^-1 PD98059,a specific ERK inhibitor did not.Lin45 gene RNAi decreased the ability of RTS on down-regulating overactivated ras significantly,but mpk1 gene RNAi did not,indicating that the activity of RTS on down-regulating overactivated ras mainly through targeting to lin45/raf.In addition,RTS significantly increased mRNA level of pmk1/p38 and jnk1/jnk in let-60/ras(gf)mutant,50μmol·L^-1 SB203580(p38 inhibitor)and SP600125(JNK inhibitor)significantly attenuated the effects of RTS on down-regulating overactivated ras in some degree,and pmk1,jnk1 gene RNAi displayed the similar results,suggesting that P38 and JNK/MAPK pathways in some degree were involved in the effects of RTS on down-regulating overactivated ras in C.ele⁃gans.CONCLUSION Realgar transforming solution down-regulate the Ras/MAPK pathway through JNK and P38 MAPK pathways.展开更多
Radiometric normalization,as an essential step for multi-source and multi-temporal data processing,has received critical attention.Relative Radiometric Normalization(RRN)method has been primarily used for eliminating ...Radiometric normalization,as an essential step for multi-source and multi-temporal data processing,has received critical attention.Relative Radiometric Normalization(RRN)method has been primarily used for eliminating the radiometric inconsistency.The radiometric trans-forming relation between the subject image and the reference image is an essential aspect of RRN.Aimed at accurate radiometric transforming relation modeling,the learning-based nonlinear regression method,Support Vector machine Regression(SVR)is used for fitting the complicated radiometric transforming relation for the coarse-resolution data-referenced RRN.To evaluate the effectiveness of the proposed method,a series of experiments are performed,including two synthetic data experiments and one real data experiment.And the proposed method is compared with other methods that use linear regression,Artificial Neural Network(ANN)or Random Forest(RF)for radiometric transforming relation modeling.The results show that the proposed method performs well on fitting the radiometric transforming relation and could enhance the RRN performance.展开更多
In operations research, the transportation problem (TP) is among the earliest and most effective applications of the linear programming problem. Unbalanced transportation problems reflect the reality of supply chain a...In operations research, the transportation problem (TP) is among the earliest and most effective applications of the linear programming problem. Unbalanced transportation problems reflect the reality of supply chain and logistics situations where the available supply of goods may not precisely match the demand at different locations. To deal with an unbalanced transportation problem (UTP), it is essential first to convert it into a balanced transportation problem (BTP) to find an initial basic feasible solution (IBFS) and hence the optimal solution. The present paper is concerned with introducing a new approach to convert an unbalanced transportation problem into a balanced one and as a consequence to obtain optimum total transportation cost. Numerical examples are provided to demonstrate the suggested method.展开更多
Burgers equation in random environment is studied. In order to give the exact solutions of random Burgers equation, we only consider the Wick-type stochastic Burgers equation which is the perturbation of the Burgers e...Burgers equation in random environment is studied. In order to give the exact solutions of random Burgers equation, we only consider the Wick-type stochastic Burgers equation which is the perturbation of the Burgers equation with variable coefficients by white noise W（t）=Bt, where Bt is a Brown motion. The auto-Baecklund transformation and stochastic soliton solutions of the Wick-type stochastic Burgers equation are shown by the homogeneous balance and Hermite transform. The generalization of the Wick-type stochastic Burgers equation is also studied.展开更多
Receiver ghost reflections adversely affect variable-depth streamer （VDS） data acquisition. In addition, the frequency notches caused by the interference between receiver ghosts and primary waves strongly affect sei...Receiver ghost reflections adversely affect variable-depth streamer （VDS） data acquisition. In addition, the frequency notches caused by the interference between receiver ghosts and primary waves strongly affect seismic data processing and imaging. We developed a high-resolution Radon transform algorithm and used it to predict receiver ghosts from VDS data. The receiver ghost reflections are subtracted and removed from the raw data. We propose a forward Radon transform operator of VDS data in the frequency domain and, based on the ray paths of the receiver ghosts, we propose an inverse Radon transform operator. We apply the proposed methodology to model and field data with good results. We use matching and subtracting modules of commercially available seismic data processing software to remove the receiver ghosts. The frequency notches are compensated and the effective frequency bandwidth of the seismic data broadens.展开更多
In this paper, it is described that the time-frequency resolution of geophysical signals is affected by the time window function attenuation coefficient and sampling interval and how such effects are eliminated effect...In this paper, it is described that the time-frequency resolution of geophysical signals is affected by the time window function attenuation coefficient and sampling interval and how such effects are eliminated effectively. Improving the signal resolution is the key to signal time-frequency analysis processing and has wide use in geophysical data processing and extraction of attribute parameters. In this paper, authors research the effects of the attenuation coefficient choice of the Gabor transform window function and sampling interval on signal resolution. Unsuitable parameters not only decrease the signal resolution on the frequency spectrum but also miss the signals. It is essential to first give the optimum window and range of parameters through time-frequency analysis simulation using the Gabor transform. In the paper, the suggestions about the range and choice of the optimum sampling interval and processing methods of general seismic signals are given.展开更多
The parabolic Radon transform has been widely used in multiple attenuation. To further improve the accuracy and efficiency of the Radon transform, we developed the 2- fdomain high-resolution Radon transform based on t...The parabolic Radon transform has been widely used in multiple attenuation. To further improve the accuracy and efficiency of the Radon transform, we developed the 2- fdomain high-resolution Radon transform based on the fast and modified parabolic Radon transform presented by Abbad. The introduction of a new variable 2 makes the transform operator frequency-independent. Thus, we need to calculate the transform operator and its inverse operator only once, which greatly improves the computational efficiency. Besides, because the primaries and multiples are distributed on straight lines with different slopes in the 2-fdomain, we can easily choose the filtering operator to suppress the multiples. At the same time, the proposed method offers the advantage of high-resolution Radon transform, which can greatly improve the precision of attenuating the multiples. Numerical experiments suggest that the multiples are well suppressed and the amplitude versus offset characteristics of the primaries are well maintained. Real data processing results further verify the effectiveness and feasibility of the method.展开更多
The transformation and dissolution of Mg（Zn, Cu, Al）2 phase during solution treatment of an Al-Zn-Mg-Cu alloy containing high zinc were investigated by means of optical microscopy （OM）, scanning electron microsco...The transformation and dissolution of Mg（Zn, Cu, Al）2 phase during solution treatment of an Al-Zn-Mg-Cu alloy containing high zinc were investigated by means of optical microscopy （OM）, scanning electron microscopy （SEM）, energy-dispersive X-ray spectrometry （EDX） and X-ray diffraction （XRD）. The results show that solution temperature is the main factor influencing phase dissolution. With solution temperature increasing, the content of residual phases decreases. Phase transformation from Mg（Zn, Cu, Al）2 to S（Al2CuMg） occurs under solution temperature of 450, 460 and 465 ℃. Mg（Zn, Cu, Al）2 phase is directly dissolved into the matrix under solution temperature of 470 and 475 ℃, and no S（Al2CuMg） phase transformed from Mg（Zn, Cu, Al）2 phase is observed. The formation of S（Al2CuMg） phase is mainly controlled by Zn elemental diffusion. The mechanism of transformation and dissolution of second phases was investigated. At low temperature, the dissolution of Zn is faster than that of Mg and Cu, resulting in an appropriate condition to form S（Al2CuMg） phase. At high temperature, the dissolution of main alloying elements has no significant barrier among them to form S（Al2CuMg） phase.展开更多
Cubic and monoclinic Gd2O3:Eu3+ phosphors in the range of nano-scale and submicron-scale were prepared by a modified solution combustion method.Coexistence of cubic and monoclinic phases was found in the highest lumin...Cubic and monoclinic Gd2O3:Eu3+ phosphors in the range of nano-scale and submicron-scale were prepared by a modified solution combustion method.Coexistence of cubic and monoclinic phases was found in the highest luminescent sample synthesized at 600 oC.In relation to commercial sample,the relative luminescence intensity was 49.8%.The shape of emission spectrum of the sample thus changed and the charge-transfer-state band of excitation spectrum slightly shift toward higher energies.With increasing the anneal...展开更多
The generalized integral transform technique （GITT） is used to find a semianalytical numerical solution for dynamic response of an axially moving Timoshenko beam with clamped-clamped and simply-supported boundary co...The generalized integral transform technique （GITT） is used to find a semianalytical numerical solution for dynamic response of an axially moving Timoshenko beam with clamped-clamped and simply-supported boundary conditions, respectively. The implementation of GITT approach for analyzing the forced vibration equation eliminates the space variable and leads to systems of second-order ordinary differential equations （ODEs） in time. The MATHEMATICA built-in function, NDSolve, is used to numerically solve the resulting transformed ODE system. The good convergence behavior of the suggested eigenfunction expansions is demonstrated for calculating the transverse deflection and the angle of rotation of the beam cross-section. Moreover, parametric studies are performed to analyze the effects of the axially moving speed, the axial tension, and the amplitude of external distributed force on the vibration amplitude of axially moving Timoshenko beams.展开更多
BACKGROUND Esophageal stricture ranks among the most significant complications following endoscopic submucosal dissection(ESD).Excessive fibrotic repair is a typical pathological feature leading to stenosis after ESD....BACKGROUND Esophageal stricture ranks among the most significant complications following endoscopic submucosal dissection(ESD).Excessive fibrotic repair is a typical pathological feature leading to stenosis after ESD.AIM To examine the effectiveness and underlying mechanism of Kangfuxin solution(KFX)in mitigating excessive fibrotic repair of the esophagus post-ESD.METHODS Pigs received KFX at 0.74 mL/kg/d for 21 days after esophageal full circumferential ESD.Endoscopic examinations occurred on days 7 and 21 post-ESD.In vitro,recombinant transforming growth factor(TGF)-β1(5 ng/mL)induced a fibrotic microenvironment in primary esophageal fibroblasts(pEsF).After 24 hours of KFX treatment(at 1.5%,1%,and 0.5%),expression ofα-smooth muscle actin-2(ACTA2),fibronectin(FN),and type collagen I was assessed.Profibrotic signaling was analyzed,including TGF-β1,Smad2/3,and phosphor-smad2/3(p-Smad2/3).RESULTS Compared to the Control group,the groups treated with KFX and prednisolone exhibited reduced esophageal stenosis,lower weight loss rates,and improved food tolerance 21 d after ESD.After treatment,Masson staining revealed thinner and less dense collagen fibers in the submucosal layer.Additionally,the expression of fibrotic effector molecules was notably inhibited.Mechanistically,KFX downregulated the transduction levels of fibrotic functional molecules such as TGF-β1,Smad2/3,and p-Smad2/3.In vitro,pEsF exposed to TGF-β1-induced fibrotic microenvironment displayed increased fibrotic activity,which was reversed by KFX treatment,leading to reduced activation of ACTA2,FN,and collagen I.The 1.5%KFX treatment group showed decreased expression of p-Smad 2/3 in TGF-β1-activated pEsF.CONCLUSION KFX showed promise as a therapeutic option for post-full circumferential esophageal ESD strictures,potentially by suppressing fibroblast fibrotic activity through modulation of the TGF-β1/Smads signaling pathway.展开更多
基金Supported by the Doctoral Research Start-up Project of Yuncheng University(YQ-2023067)Project of Shanxi Natural Science Foundation(202303021211189)+1 种基金Fund Program for the Scientific Activities of Selected Returned Overseas Professionals in Shanxi Provinces(20220036)Shanxi ProvinceIntelligent Optoelectronic Sensing Application Technology Innovation Center and Shanxi Province Optoelectronic Information Science and TechnologyLaboratory,Yuncheng University.
文摘In this study,a straightforward one-step hydrothermal method was successfully utilized to synthesize the solid solution Na_(0.9)Mg_(0.45)Ti_(3.55)O_(8)-Na_(2)Ni_(2)Ti_(6)O_(16)(NNMTO-x),where x denotes the molar percentage of Na_(2)Ni_(2)Ti_(6)O_(16)(NNTO)within Na_(0.9)Mg_(0.45)Ti_(3.55)O_(8)(NMTO),with x values of 10,20,30,40,and 50.Both XPS(X-ray Photoelectron Spectroscopy)and EDX(Energy Dispersive X-ray Spectroscopy)analyses unequivocally validated the formation of the NNMTO-x solid solutions.It was observed that when x is below 40,the NNMTO-x solid solution retains the structural characteristics of the original NMTO.However,beyond this threshold,significant alterations in crystal morphology were noted,accompanied by a noticeable decline in photocatalytic activity.Notably,the absorption edge of NNMTO-x(x<40)exhibited a shift towards the visible-light spectrum,thereby substantially broadening the absorption range.The findings highlight that NNMTO-30 possesses the most pronounced photocatalytic activity for the reduction of CO_(2).Specifically,after a 6 h irradiation period,the production rates of CO and CH_(4)were recorded at 42.38 and 1.47μmol/g,respectively.This investigation provides pivotal insights that are instrumental in the advancement of highly efficient and stable photocatalysts tailored for CO_(2)reduction processes.
基金supported by NIH grants,Nos.R01NS125074,R01AG083164,R01NS107365,and R21NS127177(to YL),1F31NS129204-01A1(to KW)and Albert Ryan Fellowship(to KW).
文摘Adult neurogenesis continuously produces new neurons critical for cognitive plasticity in adult rodents.While it is known transforming growth factor-βsignaling is important in embryonic neurogenesis,its role in postnatal neurogenesis remains unclear.In this study,to define the precise role of transforming growth factor-βsignaling in postnatal neurogenesis at distinct stages of the neurogenic cascade both in vitro and in vivo,we developed two novel inducible and cell type-specific mouse models to specifically silence transforming growth factor-βsignaling in neural stem cells in(mGFAPcre-ALK5fl/fl-Ai9)or immature neuroblasts in(DCXcreERT2-ALK5fl/fl-Ai9).Our data showed that exogenous transforming growth factor-βtreatment led to inhibition of the proliferation of primary neural stem cells while stimulating their migration.These effects were abolished in activin-like kinase 5(ALK5)knockout primary neural stem cells.Consistent with this,inhibition of transforming growth factor-βsignaling with SB-431542 in wild-type neural stem cells stimulated proliferation while inhibited the migration of neural stem cells.Interestingly,deletion of transforming growth factor-βreceptor in neural stem cells in vivo inhibited the migration of postnatal born neurons in mGFAPcre-ALK5fl/fl-Ai9 mice,while abolishment of transforming growth factor-βsignaling in immature neuroblasts in DCXcreERT2-ALK5fl/fl-Ai9 mice did not affect the migration of these cells in the hippocampus.In summary,our data supports a dual role of transforming growth factor-βsignaling in the proliferation and migration of neural stem cells in vitro.Moreover,our data provides novel insights on cell type-specific-dependent requirements of transforming growth factor-βsignaling on neural stem cell proliferation and migration in vivo.
基金supported by the China Agriculture Research System(Grant No.CARS-23-D06)the Key Research and Development Program of Shaanxi Province(Grant Nos.2024NC2-GJHX-29 and 2024NC-ZDCYL-05-08)Shaanxi Agricultural Collaborative Innovation and Extension Alliance Project(Grant No.LMZD202202).
文摘Substrate and nutrient supply are essential for vegetable cultivation in greenhouse.The strategies for plant nutrient supply vary depending on the cultivation methods or substrate dosages employed.With the development of mechanization,wide-row spacing substrate cultivation became an optimize mode of the greenhouse cucumber cultivation,aligning with the trend of intelligent agriculture.To determine the optimal nutrient solution supply amount(NS)and supply frequency(SF)for promoting the integrated growth of cucumber under wide-row spacing substrate cultivation,we explored the effects of substrate supply amount(SS),NS,and SF on cucumber yield,quality,and element utilization efficiency.A five-level quadratic orthogonal rotation combination design with three experimental factors(NS,SF,and SS)was implemented for 23 coupling treatments over three growing seasons,including spring(2022S and 2023S)and autumn(2022A).The technique for order preference by similarity to ideal solution(TOPSIS)combining weights based on game theory was applied to construct cucumber comprehensive growth evaluation model.Single and two experimental factors analyses revealed significant effects of single factors and the coupling of NS-SS,NS-SF and SS-SF on the integrated growth of cucumber for all three growing seasons.For the NS-SF-SS combination,the optimal parameters for comprehensive cucumber growth were determined as follows:levels of^(-1).68 for NS,-0.7 for SF,and^(-1).682 for SS in 2022A;-0.43 for NS,-0.06 for SF,and 0.34 for SS in 2022S;0.3 for NS,-0.02 for SF,and 0.04 for SS in 2023S.Furthermore,for SS ranges of 2.00-3.01,3.01-4.50,4.50-5.99,5.99-7.00(L·plant^(-1)),the corresponding NS and SF intervals maximizing cucumber integrated growth in spring were:0.28-0.30(L·plant^(-1))and 6(times·d^(-1)),0.26-0.30(L·plant^(-1))and 6(times·d^(-1)),0.25-0.30(L·plant^(-1))and 6(times·d^(-1)),0.23-0.30(L·plant^(-1))and 6(times·d^(-1)),respectively.With the same SS,the corresponding NS and SF intervals that maximized cucumber integrated growth in autumn were:0.10(L·plant^(-1))and 8(times·d^(-1)),0.18(L·plant^(-1))and 7(times·d^(-1)),0.30(L·plant^(-1))and 6(times·d^(-1)),0.49(L·plant^(-1))and 5(times·d^(-1)),respectively.The results provide a theoretical basis for solution management,and further in-depth research on cucumber cultivation.
基金Supported by the Jiangsu Higher School Undergraduate Innovation and Entrepreneurship Training Program(202311117078Y)。
文摘In this paper we use Böcklund transformation to construct soliton solutions for a coupled KdV system.This system was first proposed by Wang in 2010.First we generalize the well-known Bäcklund transformation for the KdV equation to such coupled KdV system.Then from a trivial seed solution,we construct soliton solutions.We also give a nonlinear superposition formula,which allows us to generate multi-soliton solutions.
基金supported by the National Key R&D Program of China (No. 2018YFA0707300)the National Natural Science Foundation of China (No. 52374376)the Introduction Plan for High end Foreign Experts, China (No. G2023105001L)。
文摘Titanium plates with a Ti−O solid solution surface-hardened layer were cold roll-bonded with 304 stainless steel plates with high work hardening rates.The evolution and mechanisms affecting the interfacial bonding strength in titanium/stainless steel laminated composites were investigated.Results indicate that the hardened layer reduces the interfacial bonding strength from over 261 MPa to less than 204 MPa.During the cold roll-bonding process,the hardened layer fractures,leading to the formation of multi-scale cracks that are difficult for the stainless steel to fill.This not only hinders the development of an interlocking interface but also leads to the presence of numerous microcracks and hardened blocks along the nearly straight interface,consequently weakening the interfacial bonding strength.In metals with high work hardening rates,the conventional approach of enhancing interface interlocking and improving interfacial bonding strength by using a surface-hardened layer becomes less effective.
文摘OBJECTIVE To investigate the effect and the mechanisms of realgar transforming solution(RTS)on down-regulating over activated ras.METHODS we used the optimizing technical processes to obtain the RTS,and eval⁃uate the mechanisms of RTS on down-regulating overactivated ras in Caenorhabditis elegans.RESULTS We found that the mRNA level of let60 and lin45 significantly decreased following exposure to RTS,but mRNA levels of mpk1 were not statistically significant in let60/ras(gf)mutant.RTS together with sorafenib(RAF inhibitors)significantly enhanced the activity of RTS on down-regulating overactivated ras more than RTS only,but 50μmol·L^-1 PD98059,a specific ERK inhibitor did not.Lin45 gene RNAi decreased the ability of RTS on down-regulating overactivated ras significantly,but mpk1 gene RNAi did not,indicating that the activity of RTS on down-regulating overactivated ras mainly through targeting to lin45/raf.In addition,RTS significantly increased mRNA level of pmk1/p38 and jnk1/jnk in let-60/ras(gf)mutant,50μmol·L^-1 SB203580(p38 inhibitor)and SP600125(JNK inhibitor)significantly attenuated the effects of RTS on down-regulating overactivated ras in some degree,and pmk1,jnk1 gene RNAi displayed the similar results,suggesting that P38 and JNK/MAPK pathways in some degree were involved in the effects of RTS on down-regulating overactivated ras in C.ele⁃gans.CONCLUSION Realgar transforming solution down-regulate the Ras/MAPK pathway through JNK and P38 MAPK pathways.
基金This research was funded by the National Natural Science Fund of China[grant number 41701415]Science fund project of Wuhan Institute of Technology[grant number K201724]Science and Technology Development Funds Project of Department of Transportation of Hubei Province[grant number 201900001].
文摘Radiometric normalization,as an essential step for multi-source and multi-temporal data processing,has received critical attention.Relative Radiometric Normalization(RRN)method has been primarily used for eliminating the radiometric inconsistency.The radiometric trans-forming relation between the subject image and the reference image is an essential aspect of RRN.Aimed at accurate radiometric transforming relation modeling,the learning-based nonlinear regression method,Support Vector machine Regression(SVR)is used for fitting the complicated radiometric transforming relation for the coarse-resolution data-referenced RRN.To evaluate the effectiveness of the proposed method,a series of experiments are performed,including two synthetic data experiments and one real data experiment.And the proposed method is compared with other methods that use linear regression,Artificial Neural Network(ANN)or Random Forest(RF)for radiometric transforming relation modeling.The results show that the proposed method performs well on fitting the radiometric transforming relation and could enhance the RRN performance.
文摘In operations research, the transportation problem (TP) is among the earliest and most effective applications of the linear programming problem. Unbalanced transportation problems reflect the reality of supply chain and logistics situations where the available supply of goods may not precisely match the demand at different locations. To deal with an unbalanced transportation problem (UTP), it is essential first to convert it into a balanced transportation problem (BTP) to find an initial basic feasible solution (IBFS) and hence the optimal solution. The present paper is concerned with introducing a new approach to convert an unbalanced transportation problem into a balanced one and as a consequence to obtain optimum total transportation cost. Numerical examples are provided to demonstrate the suggested method.
文摘Burgers equation in random environment is studied. In order to give the exact solutions of random Burgers equation, we only consider the Wick-type stochastic Burgers equation which is the perturbation of the Burgers equation with variable coefficients by white noise W（t）=Bt, where Bt is a Brown motion. The auto-Baecklund transformation and stochastic soliton solutions of the Wick-type stochastic Burgers equation are shown by the homogeneous balance and Hermite transform. The generalization of the Wick-type stochastic Burgers equation is also studied.
文摘Receiver ghost reflections adversely affect variable-depth streamer （VDS） data acquisition. In addition, the frequency notches caused by the interference between receiver ghosts and primary waves strongly affect seismic data processing and imaging. We developed a high-resolution Radon transform algorithm and used it to predict receiver ghosts from VDS data. The receiver ghost reflections are subtracted and removed from the raw data. We propose a forward Radon transform operator of VDS data in the frequency domain and, based on the ray paths of the receiver ghosts, we propose an inverse Radon transform operator. We apply the proposed methodology to model and field data with good results. We use matching and subtracting modules of commercially available seismic data processing software to remove the receiver ghosts. The frequency notches are compensated and the effective frequency bandwidth of the seismic data broadens.
基金This work was funded by National Natural Science Foundation of China-（No. 40474044）.
文摘In this paper, it is described that the time-frequency resolution of geophysical signals is affected by the time window function attenuation coefficient and sampling interval and how such effects are eliminated effectively. Improving the signal resolution is the key to signal time-frequency analysis processing and has wide use in geophysical data processing and extraction of attribute parameters. In this paper, authors research the effects of the attenuation coefficient choice of the Gabor transform window function and sampling interval on signal resolution. Unsuitable parameters not only decrease the signal resolution on the frequency spectrum but also miss the signals. It is essential to first give the optimum window and range of parameters through time-frequency analysis simulation using the Gabor transform. In the paper, the suggestions about the range and choice of the optimum sampling interval and processing methods of general seismic signals are given.
基金sponsored by the National 973 Program(No.2011CB202402)the National Natural Science Foundation of China(No.41104069)the Fundamental Research Funds for the Central Universities(No.14CX06017A)
文摘The parabolic Radon transform has been widely used in multiple attenuation. To further improve the accuracy and efficiency of the Radon transform, we developed the 2- fdomain high-resolution Radon transform based on the fast and modified parabolic Radon transform presented by Abbad. The introduction of a new variable 2 makes the transform operator frequency-independent. Thus, we need to calculate the transform operator and its inverse operator only once, which greatly improves the computational efficiency. Besides, because the primaries and multiples are distributed on straight lines with different slopes in the 2-fdomain, we can easily choose the filtering operator to suppress the multiples. At the same time, the proposed method offers the advantage of high-resolution Radon transform, which can greatly improve the precision of attenuating the multiples. Numerical experiments suggest that the multiples are well suppressed and the amplitude versus offset characteristics of the primaries are well maintained. Real data processing results further verify the effectiveness and feasibility of the method.
基金financially supported by the National Program on Key Basic Research Project of China (No. 2012CB619504)National Natural Science Foundation of China (No. 51274046)
文摘The transformation and dissolution of Mg（Zn, Cu, Al）2 phase during solution treatment of an Al-Zn-Mg-Cu alloy containing high zinc were investigated by means of optical microscopy （OM）, scanning electron microscopy （SEM）, energy-dispersive X-ray spectrometry （EDX） and X-ray diffraction （XRD）. The results show that solution temperature is the main factor influencing phase dissolution. With solution temperature increasing, the content of residual phases decreases. Phase transformation from Mg（Zn, Cu, Al）2 to S（Al2CuMg） occurs under solution temperature of 450, 460 and 465 ℃. Mg（Zn, Cu, Al）2 phase is directly dissolved into the matrix under solution temperature of 470 and 475 ℃, and no S（Al2CuMg） phase transformed from Mg（Zn, Cu, Al）2 phase is observed. The formation of S（Al2CuMg） phase is mainly controlled by Zn elemental diffusion. The mechanism of transformation and dissolution of second phases was investigated. At low temperature, the dissolution of Zn is faster than that of Mg and Cu, resulting in an appropriate condition to form S（Al2CuMg） phase. At high temperature, the dissolution of main alloying elements has no significant barrier among them to form S（Al2CuMg） phase.
基金supported by the Ministry of Science and Technology of China (2006CB601104)the Foundation of International Joint Research of Beijing (2007N08)+1 种基金Natural Science Foundation of Jiangxi Province (2009GQC0042)Foundation of Jiangxi Educational Committee (GJJ10153)
文摘Cubic and monoclinic Gd2O3:Eu3+ phosphors in the range of nano-scale and submicron-scale were prepared by a modified solution combustion method.Coexistence of cubic and monoclinic phases was found in the highest luminescent sample synthesized at 600 oC.In relation to commercial sample,the relative luminescence intensity was 49.8%.The shape of emission spectrum of the sample thus changed and the charge-transfer-state band of excitation spectrum slightly shift toward higher energies.With increasing the anneal...
基金Project supported by the Science Foundation of China University of Petroleum in Beijing(No.2462013YJRC003)
文摘The generalized integral transform technique （GITT） is used to find a semianalytical numerical solution for dynamic response of an axially moving Timoshenko beam with clamped-clamped and simply-supported boundary conditions, respectively. The implementation of GITT approach for analyzing the forced vibration equation eliminates the space variable and leads to systems of second-order ordinary differential equations （ODEs） in time. The MATHEMATICA built-in function, NDSolve, is used to numerically solve the resulting transformed ODE system. The good convergence behavior of the suggested eigenfunction expansions is demonstrated for calculating the transverse deflection and the angle of rotation of the beam cross-section. Moreover, parametric studies are performed to analyze the effects of the axially moving speed, the axial tension, and the amplitude of external distributed force on the vibration amplitude of axially moving Timoshenko beams.
基金Supported by Science and Technology Department of Sichuan Province,No.2020YFS0376National Natural Science Foundation of China,No.81900599Science and Technology Program of Hospital of TCM,Southwest Medical University,No.2022-CXTD-01.
文摘BACKGROUND Esophageal stricture ranks among the most significant complications following endoscopic submucosal dissection(ESD).Excessive fibrotic repair is a typical pathological feature leading to stenosis after ESD.AIM To examine the effectiveness and underlying mechanism of Kangfuxin solution(KFX)in mitigating excessive fibrotic repair of the esophagus post-ESD.METHODS Pigs received KFX at 0.74 mL/kg/d for 21 days after esophageal full circumferential ESD.Endoscopic examinations occurred on days 7 and 21 post-ESD.In vitro,recombinant transforming growth factor(TGF)-β1(5 ng/mL)induced a fibrotic microenvironment in primary esophageal fibroblasts(pEsF).After 24 hours of KFX treatment(at 1.5%,1%,and 0.5%),expression ofα-smooth muscle actin-2(ACTA2),fibronectin(FN),and type collagen I was assessed.Profibrotic signaling was analyzed,including TGF-β1,Smad2/3,and phosphor-smad2/3(p-Smad2/3).RESULTS Compared to the Control group,the groups treated with KFX and prednisolone exhibited reduced esophageal stenosis,lower weight loss rates,and improved food tolerance 21 d after ESD.After treatment,Masson staining revealed thinner and less dense collagen fibers in the submucosal layer.Additionally,the expression of fibrotic effector molecules was notably inhibited.Mechanistically,KFX downregulated the transduction levels of fibrotic functional molecules such as TGF-β1,Smad2/3,and p-Smad2/3.In vitro,pEsF exposed to TGF-β1-induced fibrotic microenvironment displayed increased fibrotic activity,which was reversed by KFX treatment,leading to reduced activation of ACTA2,FN,and collagen I.The 1.5%KFX treatment group showed decreased expression of p-Smad 2/3 in TGF-β1-activated pEsF.CONCLUSION KFX showed promise as a therapeutic option for post-full circumferential esophageal ESD strictures,potentially by suppressing fibroblast fibrotic activity through modulation of the TGF-β1/Smads signaling pathway.
