期刊文献+
共找到26,913篇文章
< 1 2 250 >
每页显示 20 50 100
Determination of Smoothing Factor for the Inversion of Co-seismic Slip Distribution 被引量:3
1
作者 Leyang WANG Xiong ZHAO 《Journal of Geodesy and Geoinformation Science》 2020年第1期25-35,共11页
For the determination of the smoothing factor (also known as the regularization parameter) in the co-seismic slip distribution inversion, the compromise curve between the model roughness and the data fitting residual ... For the determination of the smoothing factor (also known as the regularization parameter) in the co-seismic slip distribution inversion, the compromise curve between the model roughness and the data fitting residual is generally used to determine (in order to distinguish the method proposed in this paper, the method is called “L curve” according to its shape). Based on the L-curve, the Eclectic Intersection curve as a new method is proposed to determine the smoothing factor in this paper. The results of the simulated experiment show that the inversion accuracy of the parameters of the seismic slip distribution with the smoothing factor determined by the Eclectic Intersection curve method is better than that of the L curve method. Moreover, the Eclectic Intersection curve method and the L curve method are used to determine the smoothing factor of L’Aquila earthquake and the Taiwan Meinong earthquake slip distribution inversion respectively, and the inversion results are compared and analyzed. The analysis results show that the L’Aquila and the Taiwan Meinong actual earthquake slip distribution results are in the range of other scholars at home and abroad, and compared with the L curve method, the Eclectic Intersection curve method has advantages of high computation efficiency, no need to depend on data fitting degree and more appropriate of smoothing factor and so on. 展开更多
关键词 co-seismic slip distribution smoothing factor Eclectic INTERSECTION CURVE METHOD L CURVE METHOD the LAquila EARTHQUAKE the Meinong EARTHQUAKE
在线阅读 下载PDF
A new error-controllable method for smoothing the G01 commands 被引量:3
2
作者 Min WAN Wan-Jing XING +2 位作者 Yang LIU Qun-Bao XIAO Wei-Hong ZHANG 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2019年第7期1756-1771,共16页
In real machining, the tool paths are composed of a series of short line segments, which constitute groups of sharp corners correspondingly leading to geometry discontinuity in tangent. As a result, high acceleration ... In real machining, the tool paths are composed of a series of short line segments, which constitute groups of sharp corners correspondingly leading to geometry discontinuity in tangent. As a result, high acceleration with high fluctuation usually occurs. If these kinds of tool paths are directly used for machining, the feedrate and quality will be greatly reduced. Thus, generating continuous tool paths is strongly desired. This paper presents a new error-controllable method for generating continuous tool path. Different from the traditional method focusing on fitting the cutter locations, the proposed method realizes globally smoothing the tool path in an error-controllable way. Concretely, it does the smoothing by approaching the newly produced curve to the linear tool path by taking the tolerance requirement as a constraint. That is, the error between the desired tool path and the G01 commands are taken as a boundary condition to ensure the finally smoothed curve being within the given tolerance. Besides, to improve the smoothing ability in case of small corner angle, an improved local smoothing method is also proposed by symmetrically assigning the control points to the two adjacent linear segments with the constrains of tolerance and G3 continuity. Experiments on an open five-axis machine are developed to verify the advantages of the proposed methods. 展开更多
关键词 Energy approximation METHOD Error-controllable global smoothing METHOD G3 CONTINUITY Local smoothing METHOD Quasi-uniform quintic Bspline CURVE
原文传递
Spatially random polarization-smoothing optics by residual stress birefringence of fused silica for laser-driven inertial confinement fusion
3
作者 Chuanchao Zhang Wei Liao +6 位作者 Xiaolong Jiang Haijun Wang Fa Zeng Wei Ni Ping Li Xiaodong Jiang Qihua Zhu 《Matter and Radiation at Extremes》 2025年第5期54-63,共10页
We demonstrate a new polarization smoothing(PS)approach utilizing residual stress birefringence in fused silica to create a spatially random polarization control plate(SRPCP),thereby improving target illumination unif... We demonstrate a new polarization smoothing(PS)approach utilizing residual stress birefringence in fused silica to create a spatially random polarization control plate(SRPCP),thereby improving target illumination uniformity in inertial confinement fusion(ICF)laser systems.The fundamental operating mechanism and key fabrication techniques for the SRPCP are systematically developed and experimentally validated.The SRPCP converts a linearly polarized 3ω incident laser beam into an output beam with a spatially randomized polarization distribution.When combined with a continuous phase plate,the SRPCP effectively suppresses high-intensity speckles at all spatial frequencies in the focal spot.The proposed PS technique is specifically designed for high-fluence large-aperture laser systems,enabling novel polarization control regimes in laser-driven ICF. 展开更多
关键词 spatially ra fused silica spatially random polarization control plate srpcp thereby linearly polarized incident laser beam residual stress birefringence fabrication techniques improving target illumination uniformity spatially random polarization smoothing
在线阅读 下载PDF
New insights on the pathogenesis of pyloric stenosis of infancy. A review with emphasis on the hyperacidity theory 被引量:1
4
作者 Ian M. Rogers 《Open Journal of Pediatrics》 2012年第2期97-105,共9页
A review is presented on the theories concerning the cause of pyloric stenosis with emphasis on the primary position of inherited hyperacidity in pathogenesis. Existing theories are critically analysed and the hyperac... A review is presented on the theories concerning the cause of pyloric stenosis with emphasis on the primary position of inherited hyperacidity in pathogenesis. Existing theories are critically analysed and the hyperacidity theory is precisely defined in the light of recent physiological insights into the gastrointestinal hormone motilin. The progressive fixed fasting hypergastrinaemia within the first few weeks of life will, in the baby who inherits acid secretion at the top of the normal range, produce hyperacidity of sufficient severity to trigger the process of acid-induced work hypertrophy of the pylorus. The potential contribution of motilin is discussed. The baby who inherits a normal gastric acidity will not reach acid levels severe enough to trigger sphincter hypertrophy despite the early gastrin stimulus. The potential threat will cease when gastrin naturally declines with age and the pyloric canal becomes wider. Genetic factors clearly must also be involved and these are separately discussed. 展开更多
关键词 Infantile Hypertrophic Pyloric stenosis (IHPS) Immunohistochemistry Smooth Muscle CELLS Gastrin MOTILIN Gastrointestinal MOTILITY Erythromycin PYLOROMYOTOMY Acidification of the Stomach Pyloric SPHINCTER Function Receptor Binding Pathogenesis Antral MOTILITY Gastric Outflow Obstruction Linkage Analysis Single Nucleotide Polymorphism: Interstitial CELLS of Cahal Nitric Oxide Synthetase
暂未订购
A Smoothing Neural Network Algorithm for Absolute Value Equations 被引量:4
5
作者 Feiran Wang Zhensheng Yu Chang Gao 《Engineering(科研)》 2015年第9期567-576,共10页
In this paper, we give a smoothing neural network algorithm for absolute value equations (AVE). By using smoothing function, we reformulate the AVE as a differentiable unconstrained optimization and we establish a ste... In this paper, we give a smoothing neural network algorithm for absolute value equations (AVE). By using smoothing function, we reformulate the AVE as a differentiable unconstrained optimization and we establish a steep descent method to solve it. We prove the stability and the equilibrium state of the neural network to be a solution of the AVE. The numerical tests show the efficient of the proposed algorithm. 展开更多
关键词 ABSOLUTE VALUE EQUATIONS NEURAL Network smoothing Function Linear Complementarity PROBLEM
在线阅读 下载PDF
Mitigating Adversarial Attack through Randomization Techniques and Image Smoothing
6
作者 Hyeong-Gyeong Kim Sang-Min Choi +1 位作者 Hyeon Seo Suwon Lee 《Computers, Materials & Continua》 2025年第9期4381-4397,共17页
Adversarial attacks pose a significant threat to artificial intelligence systems by exposing them to vulnerabilities in deep learning models.Existing defense mechanisms often suffer drawbacks,such as the need for mode... Adversarial attacks pose a significant threat to artificial intelligence systems by exposing them to vulnerabilities in deep learning models.Existing defense mechanisms often suffer drawbacks,such as the need for model retraining,significant inference time overhead,and limited effectiveness against specific attack types.Achieving perfect defense against adversarial attacks remains elusive,emphasizing the importance of mitigation strategies.In this study,we propose a defense mechanism that applies random cropping and Gaussian filtering to input images to mitigate the impact of adversarial attacks.First,the image was randomly cropped to vary its dimensions and then placed at the center of a fixed 299299 space,with the remaining areas filled with zero padding.Subsequently,Gaussian×filtering with a 77 kernel and a standard deviation of two was applied using a convolution operation.Finally,the×smoothed image was fed into the classification model.The proposed defense method consistently appeared in the upperright region across all attack scenarios,demonstrating its ability to preserve classification performance on clean images while significantly mitigating adversarial attacks.This visualization confirms that the proposed method is effective and reliable for defending against adversarial perturbations.Moreover,the proposed method incurs minimal computational overhead,making it suitable for real-time applications.Furthermore,owing to its model-agnostic nature,the proposed method can be easily incorporated into various neural network architectures,serving as a fundamental module for adversarial defense strategies. 展开更多
关键词 Adversarial attacks deep learning artificial intelligence systems random cropping Gaussian filtering image smoothing
在线阅读 下载PDF
A Control Strategy for Smoothing Active Power Fluctuation of Wind Farm with Flywheel Energy Storage System Based on Improved Wind Power Prediction Algorithm
7
作者 J. C. Wang X. R. Wang 《Energy and Power Engineering》 2013年第4期387-392,共6页
The fluctuation of active power output of wind farm has many negative impacts on large-scale wind power integration into power grid. In this paper, flywheel energy storage system (FESS) was connected to AC side of the... The fluctuation of active power output of wind farm has many negative impacts on large-scale wind power integration into power grid. In this paper, flywheel energy storage system (FESS) was connected to AC side of the doubly-fed induction generator (DFIG) wind farm to realize smooth control of wind power output. Based on improved wind power prediction algorithm and wind speed-power curve modeling, a new smooth control strategy with the FESS was proposed. The requirement of power system dispatch for wind power prediction and flywheel rotor speed limit were taken into consideration during the process. While smoothing the wind power fluctuation, FESS can track short-term planned output of wind farm. It was demonstrated by quantitative analysis of simulation results that the proposed control strategy can smooth the active power fluctuation of wind farm effectively and thereby improve power quality of the power grid. 展开更多
关键词 WIND POWER Generation FESS WIND POWER Prediction IMPROVED Time-series Algorithm Active POWER Smooth Control
在线阅读 下载PDF
Adaptive Smoothing Method Based on Fuzzy Theory Study and Realization
8
作者 Yao Wan Changlin Hu 《Journal of Computer and Communications》 2015年第5期38-43,共6页
In this paper, we study about a method to optimize the fused track quality in intelligence network of radar target fusion system, considering the role of people in the fusion system;we start to find ways to optimize t... In this paper, we study about a method to optimize the fused track quality in intelligence network of radar target fusion system, considering the role of people in the fusion system;we start to find ways to optimize the quality of the fused track, and adaptive smoothing method is proposed based on fuzzy theory. Tests show that this method can greatly improve the quality of the fused track system for battlefield reconnaissance provides high-quality, high-reliability battlefield. 展开更多
关键词 ADAPTIVE smoothing Method Based on FUZZY THEORY STUDY and REALIZATION
在线阅读 下载PDF
Medical Quality-of-Service Optimization in Wireless Telemedicine System Using Optimal Smoothing Algorithm
9
作者 Sodhro Ali Hassan Ye Li 《E-Health Telecommunication Systems and Networks》 2013年第1期1-8,共8页
In this paper we consider the transmission of stored video from a server to a client for medical applications such as, Telemonitoring, to optimize medical quality of service (m-QoS) and to examine how the client buffe... In this paper we consider the transmission of stored video from a server to a client for medical applications such as, Telemonitoring, to optimize medical quality of service (m-QoS) and to examine how the client buffer space can be used efficiently and effectively towards reducing the rate variability of the compressed variable bit rate (VBR) video. Three basic results are presented. First, we show how to obtain the greatest possible reduction in rate variability when sending stored video to client with a given buffer size. Second, how to reduce high peak data rate of compressed VBR video when a patient is moving/walking very fast in hospital. Third, we evaluate the impact of optimal smoothing algorithm on the network parameters such as, peak-to-mean ratio, standard deviation, delay, jitter, average delay and average jitter to optimize the m-QoS. To resolve these all problems we used optimal smoothing algorithm and show its performance over a set of long MPEG-4 encoded video traces. Simulation results show that m-QoS is optimized by minimizing network metrics. 展开更多
关键词 WIRELESS TELEMEDICINE System MEDICAL QoS OPTIMAL smoothing Algorithm Mobile Health
暂未订购
An Inexact Implementation of Smoothing Homotopy Method for Semi-Supervised Support Vector Machines
10
作者 Huijuan Xiong Feng Shi 《Journal of Data Analysis and Information Processing》 2013年第1期1-7,共7页
Semi-supervised Support Vector Machines is an appealing method for using unlabeled data in classification. Smoothing homotopy method is one of feasible method for solving semi-supervised support vector machines. In th... Semi-supervised Support Vector Machines is an appealing method for using unlabeled data in classification. Smoothing homotopy method is one of feasible method for solving semi-supervised support vector machines. In this paper, an inexact implementation of the smoothing homotopy method is considered. The numerical implementation is based on a truncated smoothing technique. By the new technique, many “non-active” data can be filtered during the computation of every iteration so that the computation cost is reduced greatly. Besides this, the global convergence can make better local minima and then result in lower test errors. Final numerical results verify the efficiency of the method. 展开更多
关键词 SEMI-SUPERVISED Classification Support Vector Machines TRUNCATED smoothing Technique Global CONVERGENCE
在线阅读 下载PDF
Fast Ferry Smoothing Motion via Intelligent PD Controller 被引量:1
11
作者 Mounia Ticherfatine Qidan Zhu 《Journal of Marine Science and Application》 CSCD 2018年第2期273-279,共7页
A novel type of control law was adopted to reduce the vertical acceleration of a fast ferry as well as the motion sickness incidence suffered by the passengers onboard by means of a submerged T-foil.Considering the sy... A novel type of control law was adopted to reduce the vertical acceleration of a fast ferry as well as the motion sickness incidence suffered by the passengers onboard by means of a submerged T-foil.Considering the system changing characteristics under high disturbances,a model-free approach was adopted.In addition,an upgraded proportional-derivative(PD)controller with correction terms resulting from a fast-online estimation of the system dynamics was designed.The overall controller,known as intelligent PD(i-PD)controller,was tested,and the obtained results were compared with those of a classic PD controller.The controllers were also tested in a changing environment and at different operating velocities.The results confirmed the effectiveness of the i-PD controller to smooth the motions with low computational cost control schemes.Furthermore,thanks to ability of the i-PD controller to continually update the estimated dynamics of the system,it showed a better reduction in both vertical motions and the seasickness level of the passengers with the needed robustness under external disturbances and system changing parameters. 展开更多
关键词 MODEL-FREE CONTROL INTELLIGENT PD Pitchmotion Ship CONTROL T-foil smoothing MOTION
在线阅读 下载PDF
STRICHARTZ AND SMOOTHING ESTIMATES FOR DISPERSIVE SEMI-GROUP e^(-itP(D)) IN WEIGHTED L^(2) SPACES AND THEIR APPLICATIONS
12
作者 Jiecheng CHEN Shaolei RU Chenjing WU 《Acta Mathematica Scientia》 2025年第2期401-415,共15页
Combining TT* argument and bilinear interpolation,this paper obtains the Strichartz and smoothing estimates of dispersive semigroup e^(-itP(D)) in weighted L^(2) spaces.Among other things,we recover the results in[1].... Combining TT* argument and bilinear interpolation,this paper obtains the Strichartz and smoothing estimates of dispersive semigroup e^(-itP(D)) in weighted L^(2) spaces.Among other things,we recover the results in[1].Moreover,the application of these results to the well-posedness of some equations are shown in the last section. 展开更多
关键词 Strichartz estimates smoothing estimates Morrey-Campanato class weighted L^(2)spaces WELL-POSEDNESS
在线阅读 下载PDF
Sizing of Energy Storage Systems for Output Smoothing of Renewable Energy Systems 被引量:131
13
作者 王成山 于波 +1 位作者 肖峻 郭力 《中国电机工程学报》 EI CSCD 北大核心 2012年第16期I0001-I0026,共26页
光伏、风力发电等可再生能源(renewable energysources,RESs)具有随机性、间歇性等特点。为了抑制RESs输出波动对电网的不利影响,提出了用于平滑RESs发电系统功率输出的储能系统(energy storage system,ESS)容量优化确定方法。... 光伏、风力发电等可再生能源(renewable energysources,RESs)具有随机性、间歇性等特点。为了抑制RESs输出波动对电网的不利影响,提出了用于平滑RESs发电系统功率输出的储能系统(energy storage system,ESS)容量优化确定方法。利用离散傅里叶变换(discrete Fouriertransform,DFT)对RESs输出功率进行频谱分析,基于频谱分析结果,考虑ESS充放电效率、荷电状态(stateofcharge,soc)及RESs发电系统目标功率输出波动率的约束,确定所需ESS最小容量。采用美国华盛顿州实际观测风速数据及日本东北电力公司风电场接入电网20rnin有功功率波动规范(最大波动率为10%),在一风力发电系统中对该方法进行了验证。算例结果表明采用该方法能够以较小的容量将风机输出最大波动率由61.7%降到9.9%。 展开更多
关键词 RESS
原文传递
SMOOTHING AND CURVE-FITTING OF THE MEASURED DATA OF PLANE CAM PROFILE
14
作者 薛元 陈明 《Journal of China Textile University(English Edition)》 EI CAS 1994年第1期75-79,共5页
The necessary continuity of the second order derivative or curvature of the cam profile has been analyzed. In order to guarantee the smoothness of the cam radius data, a proper method with which it could be possible t... The necessary continuity of the second order derivative or curvature of the cam profile has been analyzed. In order to guarantee the smoothness of the cam radius data, a proper method with which it could be possible to revise directly the first and the second order difference coefficients as well as the slope has been proposed. This method, applicable to different cam mechanisms by using a unified formula of correction, possesses the characteristics of simplicity, intuition and precision. Meanwhile, a cubic spline function for fitting the cam profile has also been described. 展开更多
关键词 CAM mechanisms radius smoothing numerical control CAM profile DIFFERENCE coefficient
在线阅读 下载PDF
PERFORMANCE ANALYSIS FOR ATM SWITCHING OF MIXED CONTINUOUS-BIT-RATE AND BURSTY TRAFFIC WITH SMOOTHING FUNCTION
15
作者 Liao Jianxin Li Lemin Sun Hairong(Beijing University of Posts and Telecommunications, Beijing 100088) (University of Electronic Science and Tecnnclogy of China, Chengdu 610054) 《Journal of Electronics(China)》 1997年第2期133-139,共7页
Traditional packet switching networks have typically employed window-based congestion control schemes in order to regulate traffic flow. In ATM networks, the high speed of the communication links and the varied nature... Traditional packet switching networks have typically employed window-based congestion control schemes in order to regulate traffic flow. In ATM networks, the high speed of the communication links and the varied nature of the carried traffic make such schemes inappropriate. Therefore, simpler and more efficient schemes have to be proposed to improve the congestion control for ATM switching. This paper presents an exact performance analysis of ATM switching whose inputs consist of Continuous-Bit-Rate(CBR) and bursty traffic. The CBR traffic and bursty traffic are described by Bernoulli process and the Interrupted Bernoulli Process(IBP), respectively. Bursty traffic smoothing mechanism is analyzed. With the use of a recursive algorithm, the cell loss probability and the average delay for ATM switching of mixed CBR and bursty traffic are exactly calculated. Traffic smoothing could be implemented at a slower peak rate keeping the average rate constant or decreasing the average bursty length. Both numerical 展开更多
关键词 ATM Interrupted BERNOULLI process BURSTINESS TRAFFIC smoothing RECURSIVE algorithm
在线阅读 下载PDF
Dual smoothing ionospheric gradient monitoring algorithm for dual-frequency BDS GBAS 被引量:2
16
作者 Zhipeng WANG Yu YIN +3 位作者 Dan SONG Kun FANG Qiang LI Xiao LI 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2020年第12期3395-3404,共10页
In this study,a Dual Smoothing Ionospheric Gradient Monitor Algorithm(DSIGMA)was developed for Code-Carrier Divergence(CCD)faults of dual-frequency Ground-Based Augmentation Systems(GBAS)based on the Bei Dou Navigatio... In this study,a Dual Smoothing Ionospheric Gradient Monitor Algorithm(DSIGMA)was developed for Code-Carrier Divergence(CCD)faults of dual-frequency Ground-Based Augmentation Systems(GBAS)based on the Bei Dou Navigation Satellite System(BDS).Divergence-Free(DF)combinations of the signals were used to form test statistics for a dualfrequency DSIGMA.First,the single-frequency DSIGMA was reviewed,which supports the GBAS approach service type D(GAST-D)for protection against the effect of large ionospheric gradients.The single-frequency DSIGMA was used to create a novel input scheme for the dual-frequency DSIGMA by introducing DF combinations.The steady states of the test statistics were also analysed.The monitors were characterized using BDS measurement data,whereby standard deviations of 0.0432 and 0.0639 m for the proposed two test statistics were used to calculate the monitor threshold.An extensive simulation was designed to assess the monitor performance by comparing the Probability of Missed Detection(PMD)according to the differential error with the range domain PMD limits under different fault modes.The results showed that the proposed algorithm has a higher integrity performance than the single-frequency monitor.The minimum detectable divergence with the same missed probability is less than 50%that of GAST-D. 展开更多
关键词 Approach Augmentation Integrity Ionosphere-monitoring Satellite navigation smoothing algorithms Steady state Threshold
原文传递
MODE SPACE SMOOTHING ALGORITHM TO ESTIMATE DOA OF COHERENT SIGNALS IMPINGING ON UNIFORM CIRCULAR ARRAY 被引量:1
17
作者 Ma Changlin Peng Yingning Tian Lisheng Liu Jianhua(Department of Electronic Engineering, Tsinghua University, Beijing 100084) 《Journal of Electronics(China)》 1998年第4期289-295,共7页
A novel method to estimate DOA of coherent signals impinging on a uniform circular array( UCA) is presented in this paper. A virtual uniform linear array (VULA) is first derived by using spatial DFT technique, transfo... A novel method to estimate DOA of coherent signals impinging on a uniform circular array( UCA) is presented in this paper. A virtual uniform linear array (VULA) is first derived by using spatial DFT technique, transforming the UCA from element space to phase mode space to obtain the properties of ordinary ULA, and then the well known spatial smoothing technique is applied to the VULA so that the lost rank of covariance matrix due to signal coherence can be retrieved. This method makes it feasible to use the simple MUSIC algorithm to estimate DOA of coherent signals impinging on a UCA without heavy computation burden. Simulation results strongly verify the effectiveness of the algorithm. 展开更多
关键词 MODE SPACE Virtual uniform linear array Spatial smoothing
在线阅读 下载PDF
A Smoothing Penalty Function Method for the Constrained Optimization Problem 被引量:1
18
作者 Bingzhuang Liu 《Open Journal of Optimization》 2019年第4期113-126,共14页
In this paper, an approximate smoothing approach to the non-differentiable exact penalty function is proposed for the constrained optimization problem. A simple smoothed penalty algorithm is given, and its convergence... In this paper, an approximate smoothing approach to the non-differentiable exact penalty function is proposed for the constrained optimization problem. A simple smoothed penalty algorithm is given, and its convergence is discussed. A practical algorithm to compute approximate optimal solution is given as well as computational experiments to demonstrate its efficiency. 展开更多
关键词 CONSTRAINED Optimization PENALTY FUNCTION smoothing Method OPTIMAL SOLUTION
在线阅读 下载PDF
Overexpression of heme oxygenase-1 protects smooth muscle cells against oxidative injury and inhibits cell proliferation 被引量:17
19
作者 MIN ZHANG, BAO HuI ZHANG, LI CHEN, WEI AN1 Institute of Sports Medicine, The Third Hospital, Peking University, Beijing 100083, China 2Department of Cell Biology, Capital University of Medical Sciences, Beijing 100054, China 《Cell Research》 SCIE CAS CSCD 2002年第2期123-132,共10页
To investigate whether the expression of exogenous heme oxygenase-1 (HO-1) gene within vascular smooth muscle cells (VSMC) could protect the cells from free radical attack and inhibit cell proliferation, we establishe... To investigate whether the expression of exogenous heme oxygenase-1 (HO-1) gene within vascular smooth muscle cells (VSMC) could protect the cells from free radical attack and inhibit cell proliferation, we established an in vitro transfection of human HO-1 gene into rat VSMC mediated by a retroviral vector. The results showed that the profound expression of HO-1 protein as well as HO activity was 1.8- and 2.0-fold increased respectively in the transfected cells compared to the non-transfected ones. The treatment of VSMC with different concentrations of H2O2 led to the remarkable cell damage as indicated by survival rate and LDH leakage. However, the resistance of the HO-1 transfected VSMC against H2O2 was significantly raised. This protective effect was dramatically diminished when the transfected VSMC were pretreated with ZnPP-IX, a specific inhibitor of HO, for 24 h. In addition, we found that the growth potential of the transfected cells was significantly inhibited directly by increased activity of HO-1, and this effect might be related to decreased phosphorylation of MAPK. These results suggest that the overexpression of introduced hHO-1 is potentially able to reduce the risk factors of atherosclerosis, partially due to its cellular protection against oxidative injury and to its inhibitory effect on cellular proliferation. 展开更多
关键词 Animals Blotting Northern Blotting Southern Blotting Western Cell Division Cell Survival Cells Cultured Cyclic GMP Dose-Response Relationship Drug Flow Cytometry Free Radicals Genetic Vectors Heme Oxygenase (Decyclizing) Heme Oxygenase-1 Humans Hydrogen Peroxide MAP Kinase Signaling System Male Membrane Proteins Muscle Smooth Myocytes Smooth Muscle OXIDANTS Oxidative Stress Oxygen Phosphorylation RATS Rats Sprague-Dawley Research Support Non-U.S. Gov't RETROVIRIDAE Time Factors Transfection
在线阅读 下载PDF
ON TWO-DIRECTION SPATIAL SMOOTHING FOR ESTIMATION ANGLE-OF-DIRECTION OF COHERENT SIGNALS
20
作者 赵滨生 陆仲良 《Journal of Electronics(China)》 1990年第3期215-222,共8页
Based on Evans’spatial smoothing preprocessing scheme,a new approach calledtwo-direction spatial smoothing preprocessing method is presented.It is proved that the decorre-lation,the effective aperture and the maximum... Based on Evans’spatial smoothing preprocessing scheme,a new approach calledtwo-direction spatial smoothing preprocessing method is presented.It is proved that the decorre-lation,the effective aperture and the maximum number of distinguishable coherent signals(whenarray size is given)of the new method are better than those of the Evans’method.Simulationresults give a comparison between the eigenvector spectrums produced by the two methods. 展开更多
关键词 ARRAY ANTENNA COHERENT SIGNAL Two-direction spatial smoothing method
在线阅读 下载PDF
上一页 1 2 250 下一页 到第
使用帮助 返回顶部