This research explored how we can improve tsunami evacuation behavior,which has been a major social issue since the 2011 Great East Japan Earthquake and Tsunami.We introduce Nige-Tore,a smartphone app for supporting t...This research explored how we can improve tsunami evacuation behavior,which has been a major social issue since the 2011 Great East Japan Earthquake and Tsunami.We introduce Nige-Tore,a smartphone app for supporting tsunami evacuation drills,which was developed within an interdisciplinary research framework.Nige-Tore serves as an effective interface tool that successfully visualizes the dynamic interactions between human actions(evacuation behavior)and natural phenomena(tsunami behavior).Drill participants can check,on their smartphone,the estimated inundation area of the approaching tsunami,along with their own current evacuation trajectory.The results of real-world trials using NigeTore show that the app is more powerful than conventional devices and methods that have been used in tsunami evacuation training,such as hazard maps and traditional drills that do not make use of any apps,because Nige-Tore provides an interface that enables commitment and contingency thinking—which at first glance appear to represent different orientations—to not only coexist but to synergize.‘‘Commitment’’(devotion or involvement)refers to the act of immersing oneself in and viewing as absolute one particular scenario or its potential to be actualized,given conditions in which infinite scenarios may be actualized,depending on the interactions between human systems and natural systems.‘‘Contingency’’thinking(an accidental or incidental state)refers to the act of relativizing and separating oneself from any particular scenario or its potential to be actualized,given the same conditions.The synergistic effect of‘‘commitment’’and‘‘contingency’’thinking also expands people’s capacity to cope with unexpected and unforeseen events.展开更多
Rapid diagnosis of Salmonella is crucial for the effective control of food safety incidents, especially in regions with poor hygiene conditions. Polymerase chain reaction(PCR), as a promising tool for Salmonella detec...Rapid diagnosis of Salmonella is crucial for the effective control of food safety incidents, especially in regions with poor hygiene conditions. Polymerase chain reaction(PCR), as a promising tool for Salmonella detection, is facing a lack of simple and fast sensing methods that are compatible with field applications in resource-limited areas. In this work, we developed a sensing approach to identify PCR-amplified Salmonella genomic DNA with the naked eye in a snapshot. Based on the ratiometric fiuorescence signals from SYBR Green Ⅰ and Hydroxyl naphthol blue, positive samples stood out from negative ones with a distinct color pattern under UV exposure. The proposed sensing scheme enabled highly specific identification of Salmonella with a detection limit at the single-copy level. Also, as a supplement to the intuitive naked-eye visualization results, numerical analysis of the colored images was available with a smartphone app to extract RGB values from colored images. This work provides a simple, rapid, and user-friendly solution for PCR identification, which promises great potential in molecular diagnosis of Salmonella and other pathogens in field.展开更多
Accurate quantification of exercise interventions and changes in muscle function is essential for personalized health management.Electrical impedance myography(EIM)technology offers an innovative,noninvasive,painless,...Accurate quantification of exercise interventions and changes in muscle function is essential for personalized health management.Electrical impedance myography(EIM)technology offers an innovative,noninvasive,painless,and easy-to-perform solution for muscle health monitoring.However,current EIM platforms face a number of limitations,including large device size,wired connections,and instability of the electrode-skin interface,which limit their applicability for monitoring mus-cle movement.In this study,a miniature wireless EIM platform with a user-friendly smartphone app is proposed and devel-oped.The miniature,wireless,multi-frequency(20 kHz-1 MHz)EIM platform is equipped with flexible microneedle array elec-trodes(MAE).The advantages of MAEs over conventional electrodes were demonstrated by physical field modeling simula-tions and skin-electrode contact impedance comparison tests.The smartphone APP was developed to wirelessly operate the EIM platform,and to transmit and process real-time muscle impedance data.To validate its effectiveness,a seven-day adaptive fatigue training study was conducted,which demonstrated that the EIM platform was able to detect muscle adaptations and serve as a reliable indicator of fatigue.This study presents an innovative approach to applying EIM technology to muscle health monitoring and exercise testing,thereby advancing the development of personalized health management and athletic performance assessment.展开更多
creening of foodborne pathogens is important to prevent contaminated foods from their supply chains.n this study, a portable detection device was developed for rapid, sensitive and simple detection of viable almonella...creening of foodborne pathogens is important to prevent contaminated foods from their supply chains.n this study, a portable detection device was developed for rapid, sensitive and simple detection of viable almonella using a finger-actuated microfluidic chip and an improved recombinase aided amplification (RAA) assay. Improved propidium monoazide(PMAxx) was combined with RAA to enable this device to distinguish viable bacteria from dead ones. The modification of PMAxx into dead bacteria, the magnetic xtraction of nucleic acids from viable bacteria and the RAA detection of extracted nucleic acids were performed using the microfluidic chip on its supporting device by finger press-release operations. The fluorescent signal resulting from RAA amplification of the nucleic acids was collected using a USB camera nd analyzed using a self-developed smartphone App to quantitatively determine the bacterial concenration. This device could detect Salmonella typhimurium in spiked chicken meats from 1.3 × 10^(2) CFU/m L o 1.3 × 10^(7) CFU/m L in 2 h with a lower detection limit of 130 CFU/m L, and has shown its potential for on-site detection of foodborne pathogens.展开更多
Two key goals for sustainable spatial planning are to promote low-carbon travel in daily life and to enhance human wellbeing through diverse human-environment interactions.Yet,the integration of these goals has been u...Two key goals for sustainable spatial planning are to promote low-carbon travel in daily life and to enhance human wellbeing through diverse human-environment interactions.Yet,the integration of these goals has been underexplored.This study investigates the potential for experiential diversity via active travel in different resi-dential contexts within the Gävle city-region,Sweden.Over 15 months,we collected spatiotemporal data from 165 participants,analyzing 4,362 reported experiences and 13,192 GPS-derived travel trajectories.Our analysis uncovered a significant spatial discrepancy:while the travelled distances to locations of positive experiences typ-ically ranged from 1.5 km to 5 km,active travel predominated only within 1.5 km.This discrepancy persisted across urban,suburban,and peripheral contexts.Although residents in different contexts reported the same types of experiences,urban dwellers travelled about 50%farther for nature experiences compared with other positive experiences,whereas peripheral dwellers travelled twice the distance for urbanicity experiences compared with other positive experiences.Consequently,urban residents mostly relied on active travel for urbanicity experiences and motorised travel for nature experiences,with the reverse trend observed among peripheral dwellers.These results illustrate the importance of spatial scale for promoting diverse positive experiences via active travel,re-gardless of residential context.Effective planning strategies may include enhancing environmental diversity near homes and developing infrastructure that favours active over motorised travel for short to moderate distances.展开更多
基金support from the Enhancement of Societal Resiliency against Natural Disasters Program of the Cabinet Office’s Council for Science,Technology and Innovation SIP(Cross-ministerial Strategic Innovation Promotion Program)(Supervising entity:Japan Science and Technology Agency)
文摘This research explored how we can improve tsunami evacuation behavior,which has been a major social issue since the 2011 Great East Japan Earthquake and Tsunami.We introduce Nige-Tore,a smartphone app for supporting tsunami evacuation drills,which was developed within an interdisciplinary research framework.Nige-Tore serves as an effective interface tool that successfully visualizes the dynamic interactions between human actions(evacuation behavior)and natural phenomena(tsunami behavior).Drill participants can check,on their smartphone,the estimated inundation area of the approaching tsunami,along with their own current evacuation trajectory.The results of real-world trials using NigeTore show that the app is more powerful than conventional devices and methods that have been used in tsunami evacuation training,such as hazard maps and traditional drills that do not make use of any apps,because Nige-Tore provides an interface that enables commitment and contingency thinking—which at first glance appear to represent different orientations—to not only coexist but to synergize.‘‘Commitment’’(devotion or involvement)refers to the act of immersing oneself in and viewing as absolute one particular scenario or its potential to be actualized,given conditions in which infinite scenarios may be actualized,depending on the interactions between human systems and natural systems.‘‘Contingency’’thinking(an accidental or incidental state)refers to the act of relativizing and separating oneself from any particular scenario or its potential to be actualized,given the same conditions.The synergistic effect of‘‘commitment’’and‘‘contingency’’thinking also expands people’s capacity to cope with unexpected and unforeseen events.
基金supported by the Macao Science and Technology Development Fund(FDCT)(Nos.FDCT 0029/2021/A1,FDCT0002/2021/AKP,004/2023/SKL,0036/2021/APD)University of Macao(No.MYRG-GRG2023-00034-IME,SRG2024-00057IME)+2 种基金Dr.Stanley Ho Medical Development Foundation(No.SHMDF-OIRFS/2024/001)Zhuhai Huafa Group(No.HF-006-2021)Guangdong Science and Technology Department(No.2022A0505030022)。
文摘Rapid diagnosis of Salmonella is crucial for the effective control of food safety incidents, especially in regions with poor hygiene conditions. Polymerase chain reaction(PCR), as a promising tool for Salmonella detection, is facing a lack of simple and fast sensing methods that are compatible with field applications in resource-limited areas. In this work, we developed a sensing approach to identify PCR-amplified Salmonella genomic DNA with the naked eye in a snapshot. Based on the ratiometric fiuorescence signals from SYBR Green Ⅰ and Hydroxyl naphthol blue, positive samples stood out from negative ones with a distinct color pattern under UV exposure. The proposed sensing scheme enabled highly specific identification of Salmonella with a detection limit at the single-copy level. Also, as a supplement to the intuitive naked-eye visualization results, numerical analysis of the colored images was available with a smartphone app to extract RGB values from colored images. This work provides a simple, rapid, and user-friendly solution for PCR identification, which promises great potential in molecular diagnosis of Salmonella and other pathogens in field.
文摘Accurate quantification of exercise interventions and changes in muscle function is essential for personalized health management.Electrical impedance myography(EIM)technology offers an innovative,noninvasive,painless,and easy-to-perform solution for muscle health monitoring.However,current EIM platforms face a number of limitations,including large device size,wired connections,and instability of the electrode-skin interface,which limit their applicability for monitoring mus-cle movement.In this study,a miniature wireless EIM platform with a user-friendly smartphone app is proposed and devel-oped.The miniature,wireless,multi-frequency(20 kHz-1 MHz)EIM platform is equipped with flexible microneedle array elec-trodes(MAE).The advantages of MAEs over conventional electrodes were demonstrated by physical field modeling simula-tions and skin-electrode contact impedance comparison tests.The smartphone APP was developed to wirelessly operate the EIM platform,and to transmit and process real-time muscle impedance data.To validate its effectiveness,a seven-day adaptive fatigue training study was conducted,which demonstrated that the EIM platform was able to detect muscle adaptations and serve as a reliable indicator of fatigue.This study presents an innovative approach to applying EIM technology to muscle health monitoring and exercise testing,thereby advancing the development of personalized health management and athletic performance assessment.
基金funded by National Natural Science Foundation of China (No. 32071899)Walmart Foundation (No. UA2020– 154)。
文摘creening of foodborne pathogens is important to prevent contaminated foods from their supply chains.n this study, a portable detection device was developed for rapid, sensitive and simple detection of viable almonella using a finger-actuated microfluidic chip and an improved recombinase aided amplification (RAA) assay. Improved propidium monoazide(PMAxx) was combined with RAA to enable this device to distinguish viable bacteria from dead ones. The modification of PMAxx into dead bacteria, the magnetic xtraction of nucleic acids from viable bacteria and the RAA detection of extracted nucleic acids were performed using the microfluidic chip on its supporting device by finger press-release operations. The fluorescent signal resulting from RAA amplification of the nucleic acids was collected using a USB camera nd analyzed using a self-developed smartphone App to quantitatively determine the bacterial concenration. This device could detect Salmonella typhimurium in spiked chicken meats from 1.3 × 10^(2) CFU/m L o 1.3 × 10^(7) CFU/m L in 2 h with a lower detection limit of 130 CFU/m L, and has shown its potential for on-site detection of foodborne pathogens.
基金supported by funding provided by University of Gävle and Vinnova through the GeoLife Region project coordinated by Future Position X[2019-05068]K.S.was supported by a grant from Forte[2022-00841]+3 种基金S.B.was supported by a joint grant from Mistra[DIA 2019/28]Formas via the national research programme on cli-mate[2021-00416]called FAIRTRANSWe acknowledge support from the project Cycle4Climate(Grant No.CB0300173)funded by Interreg Europe’s Central Baltic programme,that inspired and enriched this paper.
文摘Two key goals for sustainable spatial planning are to promote low-carbon travel in daily life and to enhance human wellbeing through diverse human-environment interactions.Yet,the integration of these goals has been underexplored.This study investigates the potential for experiential diversity via active travel in different resi-dential contexts within the Gävle city-region,Sweden.Over 15 months,we collected spatiotemporal data from 165 participants,analyzing 4,362 reported experiences and 13,192 GPS-derived travel trajectories.Our analysis uncovered a significant spatial discrepancy:while the travelled distances to locations of positive experiences typ-ically ranged from 1.5 km to 5 km,active travel predominated only within 1.5 km.This discrepancy persisted across urban,suburban,and peripheral contexts.Although residents in different contexts reported the same types of experiences,urban dwellers travelled about 50%farther for nature experiences compared with other positive experiences,whereas peripheral dwellers travelled twice the distance for urbanicity experiences compared with other positive experiences.Consequently,urban residents mostly relied on active travel for urbanicity experiences and motorised travel for nature experiences,with the reverse trend observed among peripheral dwellers.These results illustrate the importance of spatial scale for promoting diverse positive experiences via active travel,re-gardless of residential context.Effective planning strategies may include enhancing environmental diversity near homes and developing infrastructure that favours active over motorised travel for short to moderate distances.
