Slipped capital femoral epiphysis(SCFE)is a hip disorder that predominantly affects adolescents.The primary pathological change involves the displacement of the femoral head epiphysis from its normal position at the g...Slipped capital femoral epiphysis(SCFE)is a hip disorder that predominantly affects adolescents.The primary pathological change involves the displacement of the femoral head epiphysis from its normal position at the growth plate toward the metaphysis of the femoral neck.This condition can result in hip pain,abnormal gait,and even avascular necrosis of the femoral head,significantly impacting the quality of life in adolescents.Currently,the exact etiology of SCFE remains unclear;however,evidence suggests that risk factors include endocrine disorders,metabolic conditions,and genetic diseases.Endocrine disorders encompass hypothyroidism,growth hormone abnormalities,hypogonadism,and obesity-related hormonal imbalances.Metabolic conditions involve obesity,vitamin D deficiency or rickets,and renal osteodystrophy.Genetic diseases include mutations in the COL2A1 gene,aromatase deficiency,and Prader-Willi syndrome.This review summarizes various medical conditions associated with SCFE and elucidates potential molecular mechanisms from abnormal chondrocyte function in the growth plate,hormonal imbalances and inflammatory/metabolic factors in SCFE based on relevant literature,aim to provide evidence for the prevention and treatment of SCFE.展开更多
The traditional treatment of the hip with a slip of the capital femoral epiphysis has been an in situ fixation using a single screw.This has the sanctity of a long term result.Recent literature stresses the outcomes o...The traditional treatment of the hip with a slip of the capital femoral epiphysis has been an in situ fixation using a single screw.This has the sanctity of a long term result.Recent literature stresses the outcomes of failure to restore the upper femoral alignment and on the basis of the poor results makes a plea for capital realignment.This being a recent development,it lacks the support of long term follow up and it remains to be seen if this is a better alternative of managing displaced and unstable slipped capital femoral epiphysis.The authors look at some of the available literature on the subject to highlight these controversies and their implications for orthopedic surgeons.Other controversies pertain to contralateral fixation,duration of immobilization and amount of weight bearing after an in situ fixation.展开更多
AIM: To analyze the surgical results of a slipped medial rectus muscle(MRM) after hang back recession surgery for esotropia.METHODS: Twenty-one patients who underwent reexploration for diagnosed slipped muscle after h...AIM: To analyze the surgical results of a slipped medial rectus muscle(MRM) after hang back recession surgery for esotropia.METHODS: Twenty-one patients who underwent reexploration for diagnosed slipped muscle after hang back recession surgery were included in this retrospective study. Dynamic magnetic resonance imaging was performed to identify the location of the slipped muscle.Ocular motility was evaluated with assessment with prism and cover test in gaze at cardinal positions. The operations were performed by the same consultant.Intraoperative forced duction test was performed under general anesthesia. The empty sheath of the slipped MRM was resected and the muscle was advanced to the original insertion site in all patients.RESULTS: The average age of 21 patients who had consecutive exotropia with a slipped MRM at the time of presentation was 17.4±5.4y(5-50y). The average duration between the first operation and the diagnosis of the slipped muscle was 25mo(12 to 36mo). The mean follow up after the corrective surgery was 28 mo. The mean preoperative adduction limitation in the field of action of the slipped muscle was-2.26(ranging from-1 to-4). All patients had full adduction postoperatively.CONCLUSION: The diagnosis of the slipped muscle should be confirmed during the strabismus surgery. The slipped muscle may be caused due to insufficient suture and excessive rubbing of the eye. When divergent strabismus is observed after the recession of the MRM, a slipped muscle should be considered in the differential diagnosis.展开更多
BACKGROUND Slipped capital femoral epiphysis(SCFE)occurs in adolescents and has an incidence of around 10 per 100000 children.Children presenting with a unilateral SCFE are 2335 times more likely to develop a contrala...BACKGROUND Slipped capital femoral epiphysis(SCFE)occurs in adolescents and has an incidence of around 10 per 100000 children.Children presenting with a unilateral SCFE are 2335 times more likely to develop a contralateral SCFE than the general population.Prognostic factors that have been suggested to increase the risk of contralateral slip include a younger patient,an underlying endocrine disorder,growth hormone use and a higher radiographic posterior sloping angle.However,there is still much debate on the advantages and disadvantages of prophylactic fixation of the unaffected side in an otherwise healthy patient.AIM To investigate the risk rate of contralateral SCFE and assess the(dis)advantages of prophylactic fixation of the contralateral hip.METHODS A systematic literature search was performed in the Embase,Medline,Web of Science Core Collection and Cochrane databases.Search terms included‘slipped capital femoral epiphysis,’‘fixation,’‘contralateral,’and derivatives.The eligibility of the acquired articles was independently assessed by the authors and additional relevant articles were included through cross-referencing.Publications were considered eligible for inclusion if they presented data about otherwise healthy children with primarily unilateral SCFE and the outcomes of prophylactically pinning their unaffected side,or about the rates of contralateral slips and complications thereof.The study quality of the included articles was assessed independently by the authors by means of the methodological index for non-randomized studies criteria.RESULTS Of 293 identified unique publications,we included 26 studies with a total of 12897 patients.1762 patients(14%)developed a subsequent symptomatic contralateral slip.In addition,38%of patients developed a subsequent slip on the contralateral side without experiencing clinical symptoms.The most outspoken advantage of prophylactic fixation of the contralateral hip in the literature is prevention of an(asymptomatic)slip,thus reducing the increased risk of avascular necrosis(AVN),cam morphology and osteoarthritis.Disadvantages include an increased risk of infection,AVN,peri-implant fractures,loss of fixation as well as migration of hardware and morphologic changes as a consequence of growth guidance.These risks,however,appeared to only occur incidentally and were usually mild compared to the risks involved with an actual SCFE.CONCLUSION The advantages of prophylactic pinning of the unaffected side in otherwise healthy patients with unilateral SCFE seem to outweigh the disadvantages.The final decision for treatment remains to be patient-tailored.展开更多
BACKGROUND Currents trends in pediatric orthopaedics has seen an increase in surgeries being successfully completed in an outpatient setting.Two recent examples include slipped capital femoral epiphysis(SCFE)and Bloun...BACKGROUND Currents trends in pediatric orthopaedics has seen an increase in surgeries being successfully completed in an outpatient setting.Two recent examples include slipped capital femoral epiphysis(SCFE)and Blount’s disease.Surgical indications are well-studied for each pathology,but to our knowledge,there is an absence in literature analyzing safety and efficacy of inpatient vs outpatient management of either condition.We believed there would be no increase in adverse outcomes associated with outpatient treatment of either conditions.AIM To investigate whether outpatient surgery for SCFE and Blount’s disease is associated with increased risk of adverse outcomes.METHODS The 2015-2017 American College of Surgeons National Surgical Quality Improvement Program Pediatric Registries were used to compare patient characteristics,rates of complications,and readmissions between outpatient and inpatient surgery for SCFE and Blount’s disease.RESULTS Total 1788 SCFE database entries were included,30%were performed in an outpatient setting.In situ pinning was used in 98.5%of outpatient surgeries and 87.8%of inpatient surgeries(P<0.0001).Inpatients had a greater percent of total complications than outpatients 2.57%and 1.65%respectively.Regarding Blount’s disease,outpatient surgeries constituted 41.2%of the 189 procedures included in our study.The majority of inpatients were treated with a tibial osteotomy,while the majority of outpatients had a physeal arrest(P<0.0001).Complications were encountered in 7.4%of patients,with superficial surgical site infections and wound dehiscence being the most common.1.6%of patients had a readmission.No differences in complication and readmission risks were found between inpatients and outpatients.CONCLUSION The current trend is shifting towards earlier discharges and performing procedures in an outpatient setting.This can be safely performed for a large portion of children with SCFE and Blount’s disease without increasing the risk of complications or readmissions.Osteotomies are more commonly performed in an inpatient setting where monitoring is available.展开更多
Introduction: Slipped capital femoral epiphysis (SCFE) is a common hip disorder in adolescents. The most serious complication is avascular necrosis (AVN), which has lasting sequelae. The objective of this study was to...Introduction: Slipped capital femoral epiphysis (SCFE) is a common hip disorder in adolescents. The most serious complication is avascular necrosis (AVN), which has lasting sequelae. The objective of this study was to determine the rate of AVN in stable slips. Method: We reviewed retrospectively all the children treated for SCFE between 2004 and 2008 at Princess Margaret Hospital. Results: Of a total of 67 patients, 51 (76%) were stable slips and 16 (24%) unstable. Avascular necrosis developed in 3 patients with stable slip (5.9%) and in 6 with unstable slip (37.5%). There was no statistically significant association found between AVN and age, weight, slip severity, pin position, number of pins used, experience of the surgeon or side affected. Those with stable presentations can develop AVN2, males are more likely and the possibility of developing AVN increases as the time from presentation to operation increased. Conclusion: AVN can occur in stable slips without joint penetration. This combined with male sex and increased time to operation, increases the risk of AVN.展开更多
Pseudomyogenic hemangioendothelioma is a rare, recently described neoplasm that usually presents as multifocal lesions in a single extremity. The disease has demonstrated a high propensity for infiltrative growth and ...Pseudomyogenic hemangioendothelioma is a rare, recently described neoplasm that usually presents as multifocal lesions in a single extremity. The disease has demonstrated a high propensity for infiltrative growth and local recurrence but limited metastatic potential. Variations of histological appearance and immunohistochemical signatures have been described, but typically involve spindle or polygonal cells with nuclear atypia and neutrophilic infiltration. Here we present a case report of an 8-year-old female who presented with hip pain that was initially diagnosed and managed as a slipped capital femoral epiphysis (SCFE). Subsequent evaluation led to the diagnosis of pseudomyogenic hemangioendothelioma of bone. Due to the degree of osseous destruction, described patterns of local recurrence, and metastatic potential of this neoplasm, a wide resection with endoprosthetic reconstruction of the proximal femur was performed. This case highlights the importance of due diligence in the diagnoses of SCFE and bone tumors in young patients with abnormalities of the proximal femur, including consideration of the need for biopsy.展开更多
●Fe-OC content decreased after the mattic layer slipped at the same soil horizon.●Fe-OC and Fe redox gene diversity increased after the mattic layer slipped.●The content of Fe-OC was influenced by RES-Fe and RED-Fe...●Fe-OC content decreased after the mattic layer slipped at the same soil horizon.●Fe-OC and Fe redox gene diversity increased after the mattic layer slipped.●The content of Fe-OC was influenced by RES-Fe and RED-Fe.●RES-Fe and RED-Fe are mainly driven by genes fhuE and narI,respectively.Iron(Fe)binding was an important mechanism for the stabilisation of organic carbon(C)in soils.Slipping of the mattic layer exposes soils and changes the microbial Fe cycling and iron-bound organic carbon(Fe-OC)distribution.The coupled relationships were investigated among Fe,C,and key Fe redox cycling functional genes in the alpine meadows with and without mattic layer in the Qinghai-Tibet Plateau.Compared with the meadow layer and eluvial horizon,SOC content decreased by 17.7 g kg^(-1) from 39.7−90.3 g kg^(-1) after the mattic layer slipped,while the Fe-OC%increased from 2.7%and 5.7%to 12.7%.The proportion of the residual Fe fraction(RES-Fe)increased by 5.2%to 7.9%,and the organic matter-bound Fe fraction(OM-Fe)was decreased by 6%,the shift in Fe fractions caused an increase of Fe-OC%.Furthermore,the total average signal intensity of the genes for Fe cycling and redox was increased.The proportion of RES-Fe increased with CirA,feoB,fhuE and ahpC,fnr,narJ,perR,and soxR.The proportion of RED-Fe decreased with the fhuE and narI genes.In conclusion,the shift in Fe redox genes can be expected to increase the RES-Fe fractions,which promoted the accumulation of Fe-OC after the mattic layer slipped.展开更多
Plastic strain in polycrystalline metals is highly localized in grain boundaries(GBs),slip bands(SBs)and twins.While extensive research has focused on intra-granular deformation mechanisms such as slip and twinning,st...Plastic strain in polycrystalline metals is highly localized in grain boundaries(GBs),slip bands(SBs)and twins.While extensive research has focused on intra-granular deformation mechanisms such as slip and twinning,strain localization at GBs has been largely overlooked.In this study,high-resolution digital image correlation(HRDIC)was employed to capture the strain distribution and its evolution during tension in an extruded pure Mg sheet.Particular attention was paid to strain localization at GBs and its governing factors.Results reveal that,at 3%applied strain,approximately 10%of GBs were categorized as extremely-high-strain GBs(defined as the GB where at least 20 data points have an effective shear strain(ε_(eff))value exceeding the 99th percentile of the overallεeff distribution),and the majority(84%)of them were observed to deform at even 0.5%applied strain.This suggests that early-stage deformation plays a critical role in subsequent GB strain localization.The mean strain value and grain boundary sliding(GBS)displacement of GBs increased significantly with applied strain,with progressively accelerating increasing rates observed in most instances.Most(~62%)GBs exhibiting slip transfer showed low strain,while a small fraction(~8%)of them exhibited extremely high strain.This indicates that slip transfer can mitigate GB strain localization in most cases.However,complex local conditions are also critical,and case-by-case analysis is essential.Moreover,GBs with misorientation angles ranging from 50°to 80°were found to be more likely to exhibit extremely high strain.This work provides valuable insights into GB strain localization,which is critical for further understanding the plastic deformation of polycrystalline Mg.展开更多
The interrupted fatigue test method was utilized to investigate the damage evolution mechanism of the notch high-cycle fatigue(NHCF)in Ti-55531 alloy with a multilevel lamellar microstructure.The results reveal that s...The interrupted fatigue test method was utilized to investigate the damage evolution mechanism of the notch high-cycle fatigue(NHCF)in Ti-55531 alloy with a multilevel lamellar microstructure.The results reveal that significant microvoids and microcracks predominantly initiate at α/β interfaces under various notch root radii(R).Notably,even under larger R(0.75 mm),mutual interactions of stacking faults(SFs)−deformation twins,twins−twins,and SFs−SFs are observed.Furthermore,with decreasing R(0.34 and 0.14 mm),the volume fraction of SFs escalates significantly and twins are almost absent.Moreover,activated prismatic slip system decreases with a decrease in Schmidt factor and with the further decrease in R.Finally,strain localization near α/β interfaces contributes to the initiation of fatigue microcracks.展开更多
The shallow slip deficit(SSD)during strike-slip earthquakes raises a question of how the strain budget is accommodated over multiple cycles.However,the origin of variable SSD observed in different earthquakes is still...The shallow slip deficit(SSD)during strike-slip earthquakes raises a question of how the strain budget is accommodated over multiple cycles.However,the origin of variable SSD observed in different earthquakes is still under debate because each earthquake has its unique initial stress condition.Here,we derive the slip model of the 2021 M W 7.4 Maduo earthquake in Qinghai,China,using multi-track radar images.Our results revealed that,in contrast to the large SSD on segments close to the epicenter,a much smaller SSD was observed at the west terminus of the rupture,where aftershock distribution indicates that the fault changes dip direction at 6 km depth.The 2021 Maduo earthquake thus represents an extraordinary case of significant along-strike SSD variation.After accounting for interseismic,postseismic,and diffuse off-fault deformation,we find that this variation is likely contributed by the along-dipping geometrical variation,implying that a multi-segment earthquake may leave heterogeneous stress condition on the fault with different amounts of SSD.展开更多
An MW6.0 earthquake struck Jishishan County in Linxia Prefecture,Gansu Province,on December 18,2023.In this research,Sentinel-1A satellite radar observations were used to obtain the field of coseismic deformation of t...An MW6.0 earthquake struck Jishishan County in Linxia Prefecture,Gansu Province,on December 18,2023.In this research,Sentinel-1A satellite radar observations were used to obtain the field of coseismic deformation of the Jishishan earthquake in 2023,and the geometric and fine slip distribution of the seismogenic fault were inverted using this as a constraint.The results show that the earthquake is characterized by thrust movement.The coseismic slip distribution results show that the maximum slip of this earthquake is 0.3 m.The Coulomb stress distribution shows that the whole section of the southern edge of Lajishan fault,the NWW trending segment of the northern edge of Lajishan fault and its NNW trending segment to the south of the epicenter,the northern edge of the West Qinling fault and the segment to the east of the epicenter of the Daotanghe Linxia fault are under stress loading,which indicates an increase in the potential risk of earthquakes.This research discussed the seismogenic characteristics of earthquakes and the tendency of faults.We speculate that the Jishishan earthquake is the result of the joint action of regional faults and tectonic stress.Based on the observation of seismic data,geodesy,and other geological and geophysical data,we believe that the earthquake was caused by the activation of weak areas under the crust by the local stress from the driving mechanism of the northeast expansion of Qinghai-Xizang Plateau.The seismogenic fault of this earthquake is more likely to be northeast dipping under the comprehensive consideration of various factors,which occurred on the concealed fault belonging to the eastern edge of the Jishishan fault zone.展开更多
Quantitative assessment of microscale slip activities and plastic localizations is essential for understanding the complex deformation mechanisms in crystalline materials.However,few experimental studies have been abl...Quantitative assessment of microscale slip activities and plastic localizations is essential for understanding the complex deformation mechanisms in crystalline materials.However,few experimental studies have been able to dynamically measure the deformation fields of rapidly evolving slip activities at the microscale.In this study,we used the Sampling Moire?Method(SMM)to directly measure the dynamic deformation fields of slip activities in Nickel-Based Single-Crystal(NBSC)superalloy under in-situ tensile test,and the strain and displacement fields under the evolving microplastic events with intense slip activities around the notch of the NBSC superalloy specimen were obtained for the first time.The dynamic evolution of slip bands was quantitatively characterized through detailed statistical analysis of strains and displacements under different loads.The locations of the initial appearance of slip traces were successfully predicted by the regions of plasticity localization.The results show that the deformation fields exhibit both high spatial and temporal resolutions,enabling the capture of nanometer-scale displacement fields and visualization of the dynamic fluidity of slip accumulation.This method demonstrates the superiority of the dynamic characterization of the plastic deformation field at the microscale and the promise of its application for characterizing the slip activities of various crystalline metals.展开更多
This study investigates the plastic deformation behaviour of the AZ31 magnesium alloy under various uniaxial loading conditions using in-situ neutron diffraction,the crystallite group method(CGM),and crystal plasticit...This study investigates the plastic deformation behaviour of the AZ31 magnesium alloy under various uniaxial loading conditions using in-situ neutron diffraction,the crystallite group method(CGM),and crystal plasticity modelling.A key novelty of this work is the direct,model independent determination of resolved shear stress(RSS)values for individual slip and twinning systems,as well as their critical values(CRSS),derived from lattice strains in grains with preferred orientations.The experiment was extended beyond the conventional loading paths along the normal direction(ND)and rolling direction(RD)to include compression at angles of 30°and 60°from the ND(referred to as NDC30 and NDC60 tests),which had not been investigated in previous studies.Notably,the NDC30 test,combined with diffraction measurements,was specifically designed to activate basal slip in the majority of grains while minimizing twinning,enabling clear identification of this slip system and accurate determination of its CRSS.For the first time,hardening parameters were determined by comparing the model predicted values of RSS with those obtained from diffraction measurements for each active system.These data,together with the results of macroscopic tests,were used to calibrate an elastic-plastic self-consistent(EPSC)model,which accurately reproduced stress partitioning under applied load,texture evolution,and twin activity.The integrated methodology enhances the reliability of CRSS input and improves the modelling of anisotropic plasticity in magnesium alloys by tuning intergranular interactions based on a modified Eshelby inclusion approach.展开更多
The effects of artificial aging(T6)on the creep resistance with tensile stresses in the range of 50−80 MPa at 175℃were investigated for an extruded Mg−1.22Al−0.31Ca−0.44Mn(wt.%)alloy.The Guinier-Preston(G.P.)zones pr...The effects of artificial aging(T6)on the creep resistance with tensile stresses in the range of 50−80 MPa at 175℃were investigated for an extruded Mg−1.22Al−0.31Ca−0.44Mn(wt.%)alloy.The Guinier-Preston(G.P.)zones primarily precipitate in the sample aged at 200℃for 1 h(T6-200℃/1h),while the Al_(2)Ca phases mainly precipitate in the sample aged at 275℃for 8 h(T6-275℃/8h).The T6-200℃/1h sample exhibits excellent creep resistance,with a steady-state creep rate one order of magnitude lower than that of the T6-275℃/8h sample.The abnormally high stress exponent(~8.2)observed in the T6-200℃/1h sample is associated with the power-law breakdown mechanism.TEM analysis illuminates that the creep mechanism for the T6-200℃/1h sample is cross-slip between basal and prismatic dislocations,while the T6-275℃/8h sample exhibits a mixed mechanism of dislocation cross-slip and climb.Compared with the Al_(2)Ca phase,the dense G.P.zones effectively impede dislocation climb and glide during the creep process,demonstrating superior creep resistance of the T6-200℃/1h sample.展开更多
The high-cycle fatigue fracture characteristics and damage mechanism of nickel-based single crystal superalloys at 850℃ was investigated.The results indicate that high-cycle fatigue cracks in single crystal superallo...The high-cycle fatigue fracture characteristics and damage mechanism of nickel-based single crystal superalloys at 850℃ was investigated.The results indicate that high-cycle fatigue cracks in single crystal superalloys generally originate from defect locations on the subsurface or interior of the specimen at 850℃.Under the condition of stress ratio R=0.05,as the fatigue load decreases,the high-cycle fatigue life gradually increases.The high-cycle fatigue fracture is mainly characterized by octahedral slip mechanism.At high stress and low lifespan,the fracture exhibits single or multiple slip surface features.Some fractures originate along a vertical small plane and then propagate along the{111}slip surface.At low stress and high lifespan,the fracture surface tend to alternate and expand along multiple slip planes after originating from subsurface or internal sources,exhibiting characteristics of multiple slip planes.Through electron backscatter diffraction and transmission electron microscope analysis,there is obvious oxidation behavior on the surface of the high-cycle fatigue fracture,and the fracture section is composed of oxidation layer,distortion layer,and matrix layer from the outside to the inside.Among them,the main components of the oxidation layer are oxides of Ni and Co.The distortion layer is mainly distributed in the form of elongated or short rod-shaped oxides of Al,Ta,and W.The matrix layer is a single crystal layer.Crack initiation and propagation mechanism were obtained by systematical analysis of a large number of highcycle fatigue fractures.In addition,the stress ratio of 0.05 is closer to the vibration mode of turbine blades during actual service,providing effective guidance for the study of failure and fracture mechanisms of turbine blades.展开更多
A complex geological environment with faults can be encountered in the process of coal mining.Fault activation can cause instantaneous structure slipping,releasing a significant amount of elastic strain energy during ...A complex geological environment with faults can be encountered in the process of coal mining.Fault activation can cause instantaneous structure slipping,releasing a significant amount of elastic strain energy during underground coal mining.This would trigger strong rockburst disasters.To understand the occurrence of fault-slip induced rockbursts,we developed a physical model test system for fault-slip induced rockbursts in coal mine drifts.The boundary energy storage(BES)loading apparatus and bottom rapid retraction(BRR)apparatus are designed to realize energy compensation and continuous boundary stress transfer of the surrounding rocks for instantaneous fault slip,as well as to provide space for the potential fault slip.Taking the typical fault-slip induced rockburst in the Xinjulong Coal Mine,China,as the background,we conducted a model test using the test system.The deformation and stress in the rock surrounding the drift and the support unit force during fault slip are analyzed.The deformation and failure characteristics and dynamic responses of drifts under fault-slip induced rockbursts are obtained.The test results illustrate the rationality and effectiveness of the test system.Finally,corresponding recommendations and prospects are proposed based on our findings.展开更多
Quantitative studies on the interseismic and coseismic deformation characteristics and analysis of the interplay between the seismogenic fault and neighboring faults are crucial for understanding the kinematic feature...Quantitative studies on the interseismic and coseismic deformation characteristics and analysis of the interplay between the seismogenic fault and neighboring faults are crucial for understanding the kinematic features and assessing potential seismic hazards. In this study, the interseismic and coseismic deformation of the 2023 Jishishan M_(S)6.2 earthquake(JSSEQ), including the strain rate field, the slip rates,and locking depths of the seismogenic fault during the interseismic period, were obtained. Moreover, the coseismic slip distribution and geometric attributes of the seismogenic fault were further examined.Finally, the potential earthquake hazard in the vicinity was identified by analyzing the Coulomb failure stress changes(ΔCFS). Before the JSSEQ, the maximum shear and dilatational strain rates near the epicenter were significantly lower, and the seismogenic fault was strongly coupled with thrust and dextral strike-slip motion. The maximum displacement of GNSS stations is about 25 mm, about 11 km southwest of the epicenter. The ascending and descending observations reveal a significantly thrustdominated movement, with maximum line of sight displacements of 78 and 83 mm, respectively.Comparing two coseismic slip distribution results and previous studies, it is considered that the east dipping seismogenic fault is more reasonable. The coseismic fault slip took place at a depth of 7.1-13.2 km, with a maximum slip of 0.43 m and a moment magnitude of 6.1. The earthquake resulted in noticeable stress loading on the southeastern end of the Lajishan north margin fault zone and the Lajishan south margin fault zone, as well as the western end of the West Qinling fault zone, which should be given more attention in future.展开更多
基金Supported by the Science Project of Hunan Provincial Healthy Commission,No.20230844.
文摘Slipped capital femoral epiphysis(SCFE)is a hip disorder that predominantly affects adolescents.The primary pathological change involves the displacement of the femoral head epiphysis from its normal position at the growth plate toward the metaphysis of the femoral neck.This condition can result in hip pain,abnormal gait,and even avascular necrosis of the femoral head,significantly impacting the quality of life in adolescents.Currently,the exact etiology of SCFE remains unclear;however,evidence suggests that risk factors include endocrine disorders,metabolic conditions,and genetic diseases.Endocrine disorders encompass hypothyroidism,growth hormone abnormalities,hypogonadism,and obesity-related hormonal imbalances.Metabolic conditions involve obesity,vitamin D deficiency or rickets,and renal osteodystrophy.Genetic diseases include mutations in the COL2A1 gene,aromatase deficiency,and Prader-Willi syndrome.This review summarizes various medical conditions associated with SCFE and elucidates potential molecular mechanisms from abnormal chondrocyte function in the growth plate,hormonal imbalances and inflammatory/metabolic factors in SCFE based on relevant literature,aim to provide evidence for the prevention and treatment of SCFE.
文摘The traditional treatment of the hip with a slip of the capital femoral epiphysis has been an in situ fixation using a single screw.This has the sanctity of a long term result.Recent literature stresses the outcomes of failure to restore the upper femoral alignment and on the basis of the poor results makes a plea for capital realignment.This being a recent development,it lacks the support of long term follow up and it remains to be seen if this is a better alternative of managing displaced and unstable slipped capital femoral epiphysis.The authors look at some of the available literature on the subject to highlight these controversies and their implications for orthopedic surgeons.Other controversies pertain to contralateral fixation,duration of immobilization and amount of weight bearing after an in situ fixation.
文摘AIM: To analyze the surgical results of a slipped medial rectus muscle(MRM) after hang back recession surgery for esotropia.METHODS: Twenty-one patients who underwent reexploration for diagnosed slipped muscle after hang back recession surgery were included in this retrospective study. Dynamic magnetic resonance imaging was performed to identify the location of the slipped muscle.Ocular motility was evaluated with assessment with prism and cover test in gaze at cardinal positions. The operations were performed by the same consultant.Intraoperative forced duction test was performed under general anesthesia. The empty sheath of the slipped MRM was resected and the muscle was advanced to the original insertion site in all patients.RESULTS: The average age of 21 patients who had consecutive exotropia with a slipped MRM at the time of presentation was 17.4±5.4y(5-50y). The average duration between the first operation and the diagnosis of the slipped muscle was 25mo(12 to 36mo). The mean follow up after the corrective surgery was 28 mo. The mean preoperative adduction limitation in the field of action of the slipped muscle was-2.26(ranging from-1 to-4). All patients had full adduction postoperatively.CONCLUSION: The diagnosis of the slipped muscle should be confirmed during the strabismus surgery. The slipped muscle may be caused due to insufficient suture and excessive rubbing of the eye. When divergent strabismus is observed after the recession of the MRM, a slipped muscle should be considered in the differential diagnosis.
文摘BACKGROUND Slipped capital femoral epiphysis(SCFE)occurs in adolescents and has an incidence of around 10 per 100000 children.Children presenting with a unilateral SCFE are 2335 times more likely to develop a contralateral SCFE than the general population.Prognostic factors that have been suggested to increase the risk of contralateral slip include a younger patient,an underlying endocrine disorder,growth hormone use and a higher radiographic posterior sloping angle.However,there is still much debate on the advantages and disadvantages of prophylactic fixation of the unaffected side in an otherwise healthy patient.AIM To investigate the risk rate of contralateral SCFE and assess the(dis)advantages of prophylactic fixation of the contralateral hip.METHODS A systematic literature search was performed in the Embase,Medline,Web of Science Core Collection and Cochrane databases.Search terms included‘slipped capital femoral epiphysis,’‘fixation,’‘contralateral,’and derivatives.The eligibility of the acquired articles was independently assessed by the authors and additional relevant articles were included through cross-referencing.Publications were considered eligible for inclusion if they presented data about otherwise healthy children with primarily unilateral SCFE and the outcomes of prophylactically pinning their unaffected side,or about the rates of contralateral slips and complications thereof.The study quality of the included articles was assessed independently by the authors by means of the methodological index for non-randomized studies criteria.RESULTS Of 293 identified unique publications,we included 26 studies with a total of 12897 patients.1762 patients(14%)developed a subsequent symptomatic contralateral slip.In addition,38%of patients developed a subsequent slip on the contralateral side without experiencing clinical symptoms.The most outspoken advantage of prophylactic fixation of the contralateral hip in the literature is prevention of an(asymptomatic)slip,thus reducing the increased risk of avascular necrosis(AVN),cam morphology and osteoarthritis.Disadvantages include an increased risk of infection,AVN,peri-implant fractures,loss of fixation as well as migration of hardware and morphologic changes as a consequence of growth guidance.These risks,however,appeared to only occur incidentally and were usually mild compared to the risks involved with an actual SCFE.CONCLUSION The advantages of prophylactic pinning of the unaffected side in otherwise healthy patients with unilateral SCFE seem to outweigh the disadvantages.The final decision for treatment remains to be patient-tailored.
文摘BACKGROUND Currents trends in pediatric orthopaedics has seen an increase in surgeries being successfully completed in an outpatient setting.Two recent examples include slipped capital femoral epiphysis(SCFE)and Blount’s disease.Surgical indications are well-studied for each pathology,but to our knowledge,there is an absence in literature analyzing safety and efficacy of inpatient vs outpatient management of either condition.We believed there would be no increase in adverse outcomes associated with outpatient treatment of either conditions.AIM To investigate whether outpatient surgery for SCFE and Blount’s disease is associated with increased risk of adverse outcomes.METHODS The 2015-2017 American College of Surgeons National Surgical Quality Improvement Program Pediatric Registries were used to compare patient characteristics,rates of complications,and readmissions between outpatient and inpatient surgery for SCFE and Blount’s disease.RESULTS Total 1788 SCFE database entries were included,30%were performed in an outpatient setting.In situ pinning was used in 98.5%of outpatient surgeries and 87.8%of inpatient surgeries(P<0.0001).Inpatients had a greater percent of total complications than outpatients 2.57%and 1.65%respectively.Regarding Blount’s disease,outpatient surgeries constituted 41.2%of the 189 procedures included in our study.The majority of inpatients were treated with a tibial osteotomy,while the majority of outpatients had a physeal arrest(P<0.0001).Complications were encountered in 7.4%of patients,with superficial surgical site infections and wound dehiscence being the most common.1.6%of patients had a readmission.No differences in complication and readmission risks were found between inpatients and outpatients.CONCLUSION The current trend is shifting towards earlier discharges and performing procedures in an outpatient setting.This can be safely performed for a large portion of children with SCFE and Blount’s disease without increasing the risk of complications or readmissions.Osteotomies are more commonly performed in an inpatient setting where monitoring is available.
文摘Introduction: Slipped capital femoral epiphysis (SCFE) is a common hip disorder in adolescents. The most serious complication is avascular necrosis (AVN), which has lasting sequelae. The objective of this study was to determine the rate of AVN in stable slips. Method: We reviewed retrospectively all the children treated for SCFE between 2004 and 2008 at Princess Margaret Hospital. Results: Of a total of 67 patients, 51 (76%) were stable slips and 16 (24%) unstable. Avascular necrosis developed in 3 patients with stable slip (5.9%) and in 6 with unstable slip (37.5%). There was no statistically significant association found between AVN and age, weight, slip severity, pin position, number of pins used, experience of the surgeon or side affected. Those with stable presentations can develop AVN2, males are more likely and the possibility of developing AVN increases as the time from presentation to operation increased. Conclusion: AVN can occur in stable slips without joint penetration. This combined with male sex and increased time to operation, increases the risk of AVN.
文摘Pseudomyogenic hemangioendothelioma is a rare, recently described neoplasm that usually presents as multifocal lesions in a single extremity. The disease has demonstrated a high propensity for infiltrative growth and local recurrence but limited metastatic potential. Variations of histological appearance and immunohistochemical signatures have been described, but typically involve spindle or polygonal cells with nuclear atypia and neutrophilic infiltration. Here we present a case report of an 8-year-old female who presented with hip pain that was initially diagnosed and managed as a slipped capital femoral epiphysis (SCFE). Subsequent evaluation led to the diagnosis of pseudomyogenic hemangioendothelioma of bone. Due to the degree of osseous destruction, described patterns of local recurrence, and metastatic potential of this neoplasm, a wide resection with endoprosthetic reconstruction of the proximal femur was performed. This case highlights the importance of due diligence in the diagnoses of SCFE and bone tumors in young patients with abnormalities of the proximal femur, including consideration of the need for biopsy.
基金supported by the West Light Foundation of the Chinese Academy of Sciences(Grant No.xbzg-zdsys-202009)the Second Tibetan Plateau Scientific Expedition and Research Program(Grant No.2019QZKK0603)the Strategic Priority Research Program of the Chinese Academy of Sciences(PanThird Pole Environment Study for a Green Silk Road,No:XDA20040202).
文摘●Fe-OC content decreased after the mattic layer slipped at the same soil horizon.●Fe-OC and Fe redox gene diversity increased after the mattic layer slipped.●The content of Fe-OC was influenced by RES-Fe and RED-Fe.●RES-Fe and RED-Fe are mainly driven by genes fhuE and narI,respectively.Iron(Fe)binding was an important mechanism for the stabilisation of organic carbon(C)in soils.Slipping of the mattic layer exposes soils and changes the microbial Fe cycling and iron-bound organic carbon(Fe-OC)distribution.The coupled relationships were investigated among Fe,C,and key Fe redox cycling functional genes in the alpine meadows with and without mattic layer in the Qinghai-Tibet Plateau.Compared with the meadow layer and eluvial horizon,SOC content decreased by 17.7 g kg^(-1) from 39.7−90.3 g kg^(-1) after the mattic layer slipped,while the Fe-OC%increased from 2.7%and 5.7%to 12.7%.The proportion of the residual Fe fraction(RES-Fe)increased by 5.2%to 7.9%,and the organic matter-bound Fe fraction(OM-Fe)was decreased by 6%,the shift in Fe fractions caused an increase of Fe-OC%.Furthermore,the total average signal intensity of the genes for Fe cycling and redox was increased.The proportion of RES-Fe increased with CirA,feoB,fhuE and ahpC,fnr,narJ,perR,and soxR.The proportion of RED-Fe decreased with the fhuE and narI genes.In conclusion,the shift in Fe redox genes can be expected to increase the RES-Fe fractions,which promoted the accumulation of Fe-OC after the mattic layer slipped.
基金supported by the National Natural Science Foundation of China(Nos.52571157,52171125 and 52301152)Sichuan Science and Technology Program(No.2024NSFSC0193).
文摘Plastic strain in polycrystalline metals is highly localized in grain boundaries(GBs),slip bands(SBs)and twins.While extensive research has focused on intra-granular deformation mechanisms such as slip and twinning,strain localization at GBs has been largely overlooked.In this study,high-resolution digital image correlation(HRDIC)was employed to capture the strain distribution and its evolution during tension in an extruded pure Mg sheet.Particular attention was paid to strain localization at GBs and its governing factors.Results reveal that,at 3%applied strain,approximately 10%of GBs were categorized as extremely-high-strain GBs(defined as the GB where at least 20 data points have an effective shear strain(ε_(eff))value exceeding the 99th percentile of the overallεeff distribution),and the majority(84%)of them were observed to deform at even 0.5%applied strain.This suggests that early-stage deformation plays a critical role in subsequent GB strain localization.The mean strain value and grain boundary sliding(GBS)displacement of GBs increased significantly with applied strain,with progressively accelerating increasing rates observed in most instances.Most(~62%)GBs exhibiting slip transfer showed low strain,while a small fraction(~8%)of them exhibited extremely high strain.This indicates that slip transfer can mitigate GB strain localization in most cases.However,complex local conditions are also critical,and case-by-case analysis is essential.Moreover,GBs with misorientation angles ranging from 50°to 80°were found to be more likely to exhibit extremely high strain.This work provides valuable insights into GB strain localization,which is critical for further understanding the plastic deformation of polycrystalline Mg.
基金supported by the National Natural Science Foundation of China(Nos.52061005,52261025)the Science and Technology Programs of Guizhou Province,China(Nos.YQK[2023]009,CXTD[2023]009)the Technology Innovation Leading Program of Shaanxi Province,China(No.2024ZCYYDP92)。
文摘The interrupted fatigue test method was utilized to investigate the damage evolution mechanism of the notch high-cycle fatigue(NHCF)in Ti-55531 alloy with a multilevel lamellar microstructure.The results reveal that significant microvoids and microcracks predominantly initiate at α/β interfaces under various notch root radii(R).Notably,even under larger R(0.75 mm),mutual interactions of stacking faults(SFs)−deformation twins,twins−twins,and SFs−SFs are observed.Furthermore,with decreasing R(0.34 and 0.14 mm),the volume fraction of SFs escalates significantly and twins are almost absent.Moreover,activated prismatic slip system decreases with a decrease in Schmidt factor and with the further decrease in R.Finally,strain localization near α/β interfaces contributes to the initiation of fatigue microcracks.
基金the Deep Earth Probe and Mineral Resources Exploration-National Science and Technology Major Project under Grant 2024ZD1000500。
文摘The shallow slip deficit(SSD)during strike-slip earthquakes raises a question of how the strain budget is accommodated over multiple cycles.However,the origin of variable SSD observed in different earthquakes is still under debate because each earthquake has its unique initial stress condition.Here,we derive the slip model of the 2021 M W 7.4 Maduo earthquake in Qinghai,China,using multi-track radar images.Our results revealed that,in contrast to the large SSD on segments close to the epicenter,a much smaller SSD was observed at the west terminus of the rupture,where aftershock distribution indicates that the fault changes dip direction at 6 km depth.The 2021 Maduo earthquake thus represents an extraordinary case of significant along-strike SSD variation.After accounting for interseismic,postseismic,and diffuse off-fault deformation,we find that this variation is likely contributed by the along-dipping geometrical variation,implying that a multi-segment earthquake may leave heterogeneous stress condition on the fault with different amounts of SSD.
基金National Natural Science Foundation of China(Grant Nos.41930101 and 42101096)the China Postdoctoral Science Foundation(No.2019M660091XB)+8 种基金the Key Research and Development Project of Ecological Civilization Construction in Gansu Province(No.24YFFA054)the Natural Science Foundation of Gansu Province(Grant Nos.23JRRA857,23JRRG0015,and 21JR7RA317)the Gansu Province Higher Education Institutions Young Doctor(2024QB-046)the Open Fund of Wuhan,Gravitational Field and Solid Tides,National Field Observation and Research Station(WHYWZ202403)the National Cryosphere Desert Data Center(No.E01Z790201/2021kf07)the Lanzhou Talent Innovation and Entrepreneurship(No.2022-RC-73)the Experimental Teaching Reform Project of Lanzhou Jiaotong University(2024002)the Undergraduate Teaching Reform Project of Lanzhou Jiaotong University(JGY202416)"Young Scientific and Technological Talents Supporting Project"Project of Gansu Province(Li Wei)。
文摘An MW6.0 earthquake struck Jishishan County in Linxia Prefecture,Gansu Province,on December 18,2023.In this research,Sentinel-1A satellite radar observations were used to obtain the field of coseismic deformation of the Jishishan earthquake in 2023,and the geometric and fine slip distribution of the seismogenic fault were inverted using this as a constraint.The results show that the earthquake is characterized by thrust movement.The coseismic slip distribution results show that the maximum slip of this earthquake is 0.3 m.The Coulomb stress distribution shows that the whole section of the southern edge of Lajishan fault,the NWW trending segment of the northern edge of Lajishan fault and its NNW trending segment to the south of the epicenter,the northern edge of the West Qinling fault and the segment to the east of the epicenter of the Daotanghe Linxia fault are under stress loading,which indicates an increase in the potential risk of earthquakes.This research discussed the seismogenic characteristics of earthquakes and the tendency of faults.We speculate that the Jishishan earthquake is the result of the joint action of regional faults and tectonic stress.Based on the observation of seismic data,geodesy,and other geological and geophysical data,we believe that the earthquake was caused by the activation of weak areas under the crust by the local stress from the driving mechanism of the northeast expansion of Qinghai-Xizang Plateau.The seismogenic fault of this earthquake is more likely to be northeast dipping under the comprehensive consideration of various factors,which occurred on the concealed fault belonging to the eastern edge of the Jishishan fault zone.
基金supported by the Natural Science Foundation of China(No.12372176)the National Science and Technology Major Project of China(No.J2019-IV-0007-0075)。
文摘Quantitative assessment of microscale slip activities and plastic localizations is essential for understanding the complex deformation mechanisms in crystalline materials.However,few experimental studies have been able to dynamically measure the deformation fields of rapidly evolving slip activities at the microscale.In this study,we used the Sampling Moire?Method(SMM)to directly measure the dynamic deformation fields of slip activities in Nickel-Based Single-Crystal(NBSC)superalloy under in-situ tensile test,and the strain and displacement fields under the evolving microplastic events with intense slip activities around the notch of the NBSC superalloy specimen were obtained for the first time.The dynamic evolution of slip bands was quantitatively characterized through detailed statistical analysis of strains and displacements under different loads.The locations of the initial appearance of slip traces were successfully predicted by the regions of plasticity localization.The results show that the deformation fields exhibit both high spatial and temporal resolutions,enabling the capture of nanometer-scale displacement fields and visualization of the dynamic fluidity of slip accumulation.This method demonstrates the superiority of the dynamic characterization of the plastic deformation field at the microscale and the promise of its application for characterizing the slip activities of various crystalline metals.
基金founded by the National Science Centre,Poland(NCN),under grant no.UMO-2023/49/B/ST11/00774The research(neutron diffraction experiments)leading to this result has been co-funded by the project NEPHEWS under grant agreement no.101131414 from the EU Framework Programme for Research and Innovation Horizon Europe+6 种基金Views and opinions expressed are however those of the author(s)only and do not necessarily reflect those of the European Union.Neither the European Union nor the granting authorities can be held responsible for them.Measurements were carried out at the CANAM infrastructure of the NPI CAS Rez.The employment of the CICRR infrastructure supported by MEYS project LM2023041 is acknowledgedThe Ministry of Education,Youth and Sports of the Czech Republic(MEYS),support of large research infrastructures LM2023057K.M.acknowledges support of the Czech Grant Agency under project no.25-16210SP.K.acknowledges support from the European Union's Horizon 2020 research and innovation program under the NOMATEN teaming grant agreement no.857470the European Regional Development Fund via the Foundation for Polish Science International Research Agenda Plus Program grant no.MAB PLUS/2018/8the Ministry of Science and Higher Education's initiative“Support for the Activities of Centers of Excellence Established in Poland under the Horizon 2020 Program”under agreement no.MEiN/2023/DIR/3795K.W.was partly supported by the program“Excellence initiative-research university”for the AGH University of Krakow.
文摘This study investigates the plastic deformation behaviour of the AZ31 magnesium alloy under various uniaxial loading conditions using in-situ neutron diffraction,the crystallite group method(CGM),and crystal plasticity modelling.A key novelty of this work is the direct,model independent determination of resolved shear stress(RSS)values for individual slip and twinning systems,as well as their critical values(CRSS),derived from lattice strains in grains with preferred orientations.The experiment was extended beyond the conventional loading paths along the normal direction(ND)and rolling direction(RD)to include compression at angles of 30°and 60°from the ND(referred to as NDC30 and NDC60 tests),which had not been investigated in previous studies.Notably,the NDC30 test,combined with diffraction measurements,was specifically designed to activate basal slip in the majority of grains while minimizing twinning,enabling clear identification of this slip system and accurate determination of its CRSS.For the first time,hardening parameters were determined by comparing the model predicted values of RSS with those obtained from diffraction measurements for each active system.These data,together with the results of macroscopic tests,were used to calibrate an elastic-plastic self-consistent(EPSC)model,which accurately reproduced stress partitioning under applied load,texture evolution,and twin activity.The integrated methodology enhances the reliability of CRSS input and improves the modelling of anisotropic plasticity in magnesium alloys by tuning intergranular interactions based on a modified Eshelby inclusion approach.
基金supported by the National Natural Science Foundation of China (Nos. 52175322, 52271031)the Natural Science Foundation of Jilin Province, China (No. SKL202302015)。
文摘The effects of artificial aging(T6)on the creep resistance with tensile stresses in the range of 50−80 MPa at 175℃were investigated for an extruded Mg−1.22Al−0.31Ca−0.44Mn(wt.%)alloy.The Guinier-Preston(G.P.)zones primarily precipitate in the sample aged at 200℃for 1 h(T6-200℃/1h),while the Al_(2)Ca phases mainly precipitate in the sample aged at 275℃for 8 h(T6-275℃/8h).The T6-200℃/1h sample exhibits excellent creep resistance,with a steady-state creep rate one order of magnitude lower than that of the T6-275℃/8h sample.The abnormally high stress exponent(~8.2)observed in the T6-200℃/1h sample is associated with the power-law breakdown mechanism.TEM analysis illuminates that the creep mechanism for the T6-200℃/1h sample is cross-slip between basal and prismatic dislocations,while the T6-275℃/8h sample exhibits a mixed mechanism of dislocation cross-slip and climb.Compared with the Al_(2)Ca phase,the dense G.P.zones effectively impede dislocation climb and glide during the creep process,demonstrating superior creep resistance of the T6-200℃/1h sample.
基金National Science and Technology Major Project(J2019-VI-0022-0138)。
文摘The high-cycle fatigue fracture characteristics and damage mechanism of nickel-based single crystal superalloys at 850℃ was investigated.The results indicate that high-cycle fatigue cracks in single crystal superalloys generally originate from defect locations on the subsurface or interior of the specimen at 850℃.Under the condition of stress ratio R=0.05,as the fatigue load decreases,the high-cycle fatigue life gradually increases.The high-cycle fatigue fracture is mainly characterized by octahedral slip mechanism.At high stress and low lifespan,the fracture exhibits single or multiple slip surface features.Some fractures originate along a vertical small plane and then propagate along the{111}slip surface.At low stress and high lifespan,the fracture surface tend to alternate and expand along multiple slip planes after originating from subsurface or internal sources,exhibiting characteristics of multiple slip planes.Through electron backscatter diffraction and transmission electron microscope analysis,there is obvious oxidation behavior on the surface of the high-cycle fatigue fracture,and the fracture section is composed of oxidation layer,distortion layer,and matrix layer from the outside to the inside.Among them,the main components of the oxidation layer are oxides of Ni and Co.The distortion layer is mainly distributed in the form of elongated or short rod-shaped oxides of Al,Ta,and W.The matrix layer is a single crystal layer.Crack initiation and propagation mechanism were obtained by systematical analysis of a large number of highcycle fatigue fractures.In addition,the stress ratio of 0.05 is closer to the vibration mode of turbine blades during actual service,providing effective guidance for the study of failure and fracture mechanisms of turbine blades.
基金support from the National Natural Science Foundation of China (Grant Nos.51927807,42077267 and 42277174).
文摘A complex geological environment with faults can be encountered in the process of coal mining.Fault activation can cause instantaneous structure slipping,releasing a significant amount of elastic strain energy during underground coal mining.This would trigger strong rockburst disasters.To understand the occurrence of fault-slip induced rockbursts,we developed a physical model test system for fault-slip induced rockbursts in coal mine drifts.The boundary energy storage(BES)loading apparatus and bottom rapid retraction(BRR)apparatus are designed to realize energy compensation and continuous boundary stress transfer of the surrounding rocks for instantaneous fault slip,as well as to provide space for the potential fault slip.Taking the typical fault-slip induced rockburst in the Xinjulong Coal Mine,China,as the background,we conducted a model test using the test system.The deformation and stress in the rock surrounding the drift and the support unit force during fault slip are analyzed.The deformation and failure characteristics and dynamic responses of drifts under fault-slip induced rockbursts are obtained.The test results illustrate the rationality and effectiveness of the test system.Finally,corresponding recommendations and prospects are proposed based on our findings.
基金funded by the National Natural Science Foundation of China (Grant No. 42204008)the National Key Research and Development Program of China (No. 2022YFC3003703)the Scientific Research Project Coordinating Fund of the First Monitoring and Application Center, China Earthquake Administration (No. FMC2022014)
文摘Quantitative studies on the interseismic and coseismic deformation characteristics and analysis of the interplay between the seismogenic fault and neighboring faults are crucial for understanding the kinematic features and assessing potential seismic hazards. In this study, the interseismic and coseismic deformation of the 2023 Jishishan M_(S)6.2 earthquake(JSSEQ), including the strain rate field, the slip rates,and locking depths of the seismogenic fault during the interseismic period, were obtained. Moreover, the coseismic slip distribution and geometric attributes of the seismogenic fault were further examined.Finally, the potential earthquake hazard in the vicinity was identified by analyzing the Coulomb failure stress changes(ΔCFS). Before the JSSEQ, the maximum shear and dilatational strain rates near the epicenter were significantly lower, and the seismogenic fault was strongly coupled with thrust and dextral strike-slip motion. The maximum displacement of GNSS stations is about 25 mm, about 11 km southwest of the epicenter. The ascending and descending observations reveal a significantly thrustdominated movement, with maximum line of sight displacements of 78 and 83 mm, respectively.Comparing two coseismic slip distribution results and previous studies, it is considered that the east dipping seismogenic fault is more reasonable. The coseismic fault slip took place at a depth of 7.1-13.2 km, with a maximum slip of 0.43 m and a moment magnitude of 6.1. The earthquake resulted in noticeable stress loading on the southeastern end of the Lajishan north margin fault zone and the Lajishan south margin fault zone, as well as the western end of the West Qinling fault zone, which should be given more attention in future.