The experimental realization of observable phonon angular momentum(PAM)in feasible systems using relatively simple methods remains a critical challenge.Motivated by the chiral-induced spin selectivity effect,this stud...The experimental realization of observable phonon angular momentum(PAM)in feasible systems using relatively simple methods remains a critical challenge.Motivated by the chiral-induced spin selectivity effect,this study explores the generation of PAM during the transport of electrically driven polarons along a singlestranded helix structure.We demonstrate that the motion of a polaron under an applied electric field inherently induces a finite PAM,exhibiting drift-locked behavior between the PAM and the polaron.By analyzing the time evolution of PAM distribution at each site,we identify the observed PAM as a natural consequence of coherent superposition between lattice waves,in which the chiral structure selectively determines the direction of induced PAM.Furthermore,we examine the roles of two types of electron-phonon interactions and structural periodicity in modulating PAM.These findings highlight the potential of chiral molecules as platforms for PAM generation and offer new insights into developing phonon-spin-based devices for information processing and transmission.展开更多
Previous studies in our laboratory have demonstrated that the thermosensitivity locus cosegregates with blood pressure and that the elevated expression and restriction fragment length polymorphism of HSP70 gene are as...Previous studies in our laboratory have demonstrated that the thermosensitivity locus cosegregates with blood pressure and that the elevated expression and restriction fragment length polymorphism of HSP70 gene are associ-ated with hypertension. Cell protection against environ-mental stressors such as heat and chemicals is often accom-panied by up-regulated expression of a wide spectrum of heat sliock genes(HSP). To further investigate the interre-lation between HSP expression and blood pressure regulation, we employed an effective method of cloning 2 poten-tial hypertension-related HSPs. Synthetic oligonucleotides corresponding either to a higbly-conserved region of the known HSP family or a repetitive sequence in the protein- encoding gene were used as target primers for polymerase chain reaction (PCR). cDNA prepared from heat-stressed and non-stressed vascular smooth muscle cells (VSMC) of Brown Norway rats (BN.1x) and spontaneously hyperten-sive rats (SHRp) respectively served as template in the reaction. The PCR products were subsequently analyzed in a single-stranded conformational polymorphism (SSCP) electrophoresing system. Differential gene expression in BN.1x and SHRp was seen on autoradiographs of SSCP gel by comparing the migration patterns of PCR-amplified DNA fragments. Using this technique, we also found that HSP27 and a new member of the large HSP gene family were differentially expressed in BN.1x and SHRp VSMC.展开更多
基金supported by the National Key R&D Project from Ministry of Science and Technology of China(Grant No.2022YFA1203100)the National Natural Science Foundation of China(Grant No.52350088)+1 种基金the Department of Science and Technology of Jiangsu Province(Grant No.BK20220032)the Postgraduate Research&Practice Innovation Program of Jiangsu Province(Grant No.KYCX241797)。
文摘The experimental realization of observable phonon angular momentum(PAM)in feasible systems using relatively simple methods remains a critical challenge.Motivated by the chiral-induced spin selectivity effect,this study explores the generation of PAM during the transport of electrically driven polarons along a singlestranded helix structure.We demonstrate that the motion of a polaron under an applied electric field inherently induces a finite PAM,exhibiting drift-locked behavior between the PAM and the polaron.By analyzing the time evolution of PAM distribution at each site,we identify the observed PAM as a natural consequence of coherent superposition between lattice waves,in which the chiral structure selectively determines the direction of induced PAM.Furthermore,we examine the roles of two types of electron-phonon interactions and structural periodicity in modulating PAM.These findings highlight the potential of chiral molecules as platforms for PAM generation and offer new insights into developing phonon-spin-based devices for information processing and transmission.
文摘Previous studies in our laboratory have demonstrated that the thermosensitivity locus cosegregates with blood pressure and that the elevated expression and restriction fragment length polymorphism of HSP70 gene are associ-ated with hypertension. Cell protection against environ-mental stressors such as heat and chemicals is often accom-panied by up-regulated expression of a wide spectrum of heat sliock genes(HSP). To further investigate the interre-lation between HSP expression and blood pressure regulation, we employed an effective method of cloning 2 poten-tial hypertension-related HSPs. Synthetic oligonucleotides corresponding either to a higbly-conserved region of the known HSP family or a repetitive sequence in the protein- encoding gene were used as target primers for polymerase chain reaction (PCR). cDNA prepared from heat-stressed and non-stressed vascular smooth muscle cells (VSMC) of Brown Norway rats (BN.1x) and spontaneously hyperten-sive rats (SHRp) respectively served as template in the reaction. The PCR products were subsequently analyzed in a single-stranded conformational polymorphism (SSCP) electrophoresing system. Differential gene expression in BN.1x and SHRp was seen on autoradiographs of SSCP gel by comparing the migration patterns of PCR-amplified DNA fragments. Using this technique, we also found that HSP27 and a new member of the large HSP gene family were differentially expressed in BN.1x and SHRp VSMC.
