Gauss radial basis functions(GRBF)are frequently employed in data fitting and machine learning.Their linear independence property can theoretically guarantee the avoidance of data redundancy.In this paper,one of the m...Gauss radial basis functions(GRBF)are frequently employed in data fitting and machine learning.Their linear independence property can theoretically guarantee the avoidance of data redundancy.In this paper,one of the main contributions is proving this property using linear algebra instead of profound knowledge.This makes it easy to read and understand this fundamental fact.The proof of linear independence of a set of Gauss functions relies on the constructing method for one-dimensional space and on the deducing method for higher dimensions.Additionally,under the condition of preserving the same moments between the original function and interpolating function,both the interpolating existence and uniqueness are proven for GRBF in one-dimensional space.The final work demonstrates the application of the GRBF method to locate lunar olivine.By combining preprocessed data using GRBF with the removing envelope curve method,a program is created to find the position of lunar olivine based on spectrum data,and the numerical experiment shows that it is an effective scheme.展开更多
This paper investigates the problem of target position estimation with a single-observer passive coherent location（PCL） system. An approach that combines angle with time difference of arrival（ATDOA） is used to est...This paper investigates the problem of target position estimation with a single-observer passive coherent location（PCL） system. An approach that combines angle with time difference of arrival（ATDOA） is used to estimate the location of a target. Compared with the TDOA-only method which needs two steps, the proposed method estimates the target position more directly. The constrained total least squares（CTLS） technique is applied in this approach. It achieves the Cramer–Rao lower bound（CRLB） when the parameter measurements are subject to small Gaussian-distributed errors. Performance analysis and the CRLB of this approach are also studied. Theory verifies that the ATDOA method gets a lower CRLB than the TDOA-only method with the same TDOA measuring error. It can also be seen that the position of the target affects estimating precision.At the same time, the locations of transmitters affect the precision and its gradient direction.Compared with the TDOA, the ATDOA method can obtain more precise target position estimation.Furthermore, the proposed method accomplishes target position estimation with a single transmitter,while the TDOA-only method needs at least four transmitters to get the target position. Furthermore,the transmitters＇ position errors also affect precision of estimation regularly.展开更多
As an important parameter in the single airborne passive locating system, the rate of phase difference change contains range information of the radio emitter. Taking single carrier sine pulse signals as an example, th...As an important parameter in the single airborne passive locating system, the rate of phase difference change contains range information of the radio emitter. Taking single carrier sine pulse signals as an example, this article illustrates the principle of passive location through measurement of rates of phase difference change and analyzes the structure of measurement errors. On the basis of the Cramér-Rao lower bound (CRLB), an algorithm associated with time-chips is proposed to determine the rates of pha...展开更多
The intersection method is one of the basic approaches for locating earthquakes and is not only robust but also efficient. However, its location accuracy is not high, especially for focal depth because the velocity mo...The intersection method is one of the basic approaches for locating earthquakes and is not only robust but also efficient. However, its location accuracy is not high, especially for focal depth because the velocity model used for the conventional intersection method is based on homogeneous or laterally homogeneous media, which is too simple. In order to improve the accuracy, we have modified the existing intersection method. In the modified approach, the earthquake loci are not assumed to be circular or hyperbolic and calculation accuracy is improved using a minimum traveltime tree algorithm for tracing rays. The numerical model shows that the modified method can locate earthquakes in complex velocity models.展开更多
A conventional non-computerized numerical control （CNC） machine is updated by mounting a six degree-of-free （DOF） parallel mechanism on it, thus obtaining a new CNC one. The structure of this CNC milling machine i...A conventional non-computerized numerical control （CNC） machine is updated by mounting a six degree-of-free （DOF） parallel mechanism on it, thus obtaining a new CNC one. The structure of this CNC milling machine is introduced, and the workpiece locating system and the post processing system of the cutter location （CL） data file are analyzed. The new machine has advantages of low costs, simple structure, good rigidity, and high precision. It is easy to be transformed and used to process the workpiece with a complex surface.展开更多
A velocity model is an important factor influencing microseismic event locations. We re- view the velocity modeling and inversion techniques for locating microseismic events in exploration for unconventional oil and g...A velocity model is an important factor influencing microseismic event locations. We re- view the velocity modeling and inversion techniques for locating microseismic events in exploration for unconventional oil and gas reservoirs. We first describe the geological and geophysical characteristics of reservoir formations related to hydraulic fracturing in heterogeneity, anisotropy, and variability, then discuss the influences of velocity estimation, anisotropy model, and their time-lapse changes on the accuracy in determining microseismic event locations, and then survey some typical methods for building velocity models in locating event locations. We conclude that the three tangled physical attributes of reservoirs make microseismic monitoring very challenging. The uncertainties in velocity model and ignoring its anisotropies and its variations in hydraulic fracturing can cause systematic mislocations of microseismie events which are unacceptable in microseismic monitoring. So, we propose some potential ways for building accurate velocity models.展开更多
Since GPS signals are unavailable for indoor navigation, current research mainly focuses on vision-based locating with a single mark. An obvious disadvantage with this approach is that locating will fail when the mark...Since GPS signals are unavailable for indoor navigation, current research mainly focuses on vision-based locating with a single mark. An obvious disadvantage with this approach is that locating will fail when the mark cannot be seen. The use of multiple marks can solve this problem. However, the extra process to design and identify different marks will significantly increase system complexity. In this paper, a novel vision-based locating method is proposed by using marks with feature points arranged in a radial shape. The feature points of the marks consist of inner points and outer points. The positions of the inner points are the same in all marks, while the positions of the outer points are different in different marks. Unlike traditional camera locating methods （the PnP methods）, the proposed method can calculate the camera location and the positions of the outer points simultaneously. Then the calculation results of the positions of the outer points are used to identify the mark. This method can make navigation with multiple marks more efficient. Simulations and real world experiments are carried out, and their results show that the proposed method is fast, accurate and robust to noise.展开更多
Drogue recognition and 3D locating is a key problem during the docking phase of the autonomous aerial refueling （AAR）. To solve this problem, a novel and effective method based on monocular vision is presented in th...Drogue recognition and 3D locating is a key problem during the docking phase of the autonomous aerial refueling （AAR）. To solve this problem, a novel and effective method based on monocular vision is presented in this paper. Firstly, by employing computer vision with red-ring-shape feature, a drogue detection and recognition algorithm is proposed to guarantee safety and ensure the robustness to the drogue diversity and the changes in environmental condi- tions, without using a set of infrared light emitting diodes （LEDs） on the parachute part of the dro- gue. Secondly, considering camera lens distortion, a monocular vision measurement algorithm for drogue 3D locating is designed to ensure the accuracy and real-time performance of the system, with the drogue attitude provided. Finally, experiments are conducted to demonstrate the effective- ness of the proposed method. Experimental results show the performances of the entire system in contrast with other methods, which validates that the proposed method can recognize and locate the drogue three dimensionally, rapidly and precisely.展开更多
Technology of passive location has broad prospects in applications. In this paper, the method using the phase rate of change for the single observer passive location is introduced based on existing methods. One can ob...Technology of passive location has broad prospects in applications. In this paper, the method using the phase rate of change for the single observer passive location is introduced based on existing methods. One can obtain the direction of the target with phase information of two orthogonal interferometers on the observer and the radial distance with the corresponding phase rate of change. Then the target can be located with high speed and precision. A locating approach is given when the flying posture of t...展开更多
In addition to the canonical nucleobases, a variety of chemical modifications have been identified presence in nucleic acids. These modifications have been demonstrated to involve in regulating the spatiotemporal expr...In addition to the canonical nucleobases, a variety of chemical modifications have been identified presence in nucleic acids. These modifications have been demonstrated to involve in regulating the spatiotemporal expression of genes. Up to date, over 150 types of chemical modifications have been found existence in nucleic acids. Understanding the functional roles of modifications relies on deciphering the location information of modifications in nucleic acids. Analytical methods for studying nucleic acid modifications have greatly advanced in the last decade. To locate the modifications in nucleic acids, various mass spectrometry (MS)-based analytical strategies have been established. Recent progress in next-generation sequencing (NGS) in conjugation with immunoprecipitation, chemical reaction, enzyme-mediated mutation, or nanomaterials offer genome-wide or transcriptome-wide mapping of modifications, which greatly revolutionize the field of epigenetic modifications. Herein, we reviewed and summarized the established methods and the breakthrough of the techniques for locating modifications in nucleic acids. In addition, we discussed the principles, applications, advantages and drawbacks of these methods. We believe that with the rapid advancement of techniques and methods,the functions of nucleic acid modifications will be fully understood in the future.展开更多
in order to achieve a more efficient way to accurately detect the position of the fire source of spontaneous combustion underground mine, a simple fire source locating method, based on infrared scanning system which c...in order to achieve a more efficient way to accurately detect the position of the fire source of spontaneous combustion underground mine, a simple fire source locating method, based on infrared scanning system which can determine the point where the highest temperature on the surface of igniting ores occurs, was proposed. First, the differential equations that describe heat flow in ore body were presented and the relationship between the surface temperature distribution and the depth and intensity of inner fire source was established with a relatively simple heat transfer model. With the solution of equation, the expression of the relationship between the surface temperature distribution and the inner fire source was deduced and the mathematical-physical model of heat transfer process was set up. Then, with the model, visualization of fire source on the basis of MATLAB simulation platform was realized. The results show that： 1） within 10 m, when the detecting depth is less than 2 m, the temperature perturbation on ores surface can change rapidly, and then slowly; after 4 m, in contrast, it changes very little, and is even close to zero at 10 m; 2） When it is close to self-ignition duration and the detective depths are 2, 5 and 10 m, respectively, the maximum temperature differences are correspondingly 0.5, 0.04 and 0.005 ℃ in the scope of 1 m×1 m; under the same condition, the maximum temperature differences are 1.391, 0.136 and 0.018 ℃, respectively, in the scope of 2 m×2 m. Therefore, this system can be used to measure the temperature differences on the surface of ore body and determine the highest temperature point directly. Also, it is possible to determine the depth of fire source and its intensity by locating method of fire source indirectly.展开更多
Fixture locating layout has a direct and influential impact on aeronautical thin-walled component(ATWC)manufacturing quality.The purpose is to develop a topological optimization method for ATWC fixture locating layout...Fixture locating layout has a direct and influential impact on aeronautical thin-walled component(ATWC)manufacturing quality.The purpose is to develop a topological optimization method for ATWC fixture locating layout to minimize the manufacturing deformation.Firstly,a topological optimization model that takes the stiffness of ATWC as the objective function and the volume of the locating structure as the constraint is established.Secondly,ATWC and the locating structure are regarded as an integrated entity,and the variable-density method based topological optimization approach is adopted for the optimization of the locating structure using ABAQUS topology optimization module(ATOM).Thirdly,through a subsequent model reconstruction referring to the obtained topological structure,the optimal fixture locating layout is achieved.Finally,a case study is conducted to verify the proposed method and the comparison results with firefly algorithm(FA)coupled with finite element analysis(FEA)indicate that the number and positions of the locators for ATWC can be optimized simultaneously and successfully by the proposed topological optimization model.展开更多
To improve the efficiency and accuracy of single-event effect(SEE)research at the Heavy Ion Research Facility at Lanzhou,Hi’Beam-SEE must precisely localize the position at which each heavy ion hitting the integrated...To improve the efficiency and accuracy of single-event effect(SEE)research at the Heavy Ion Research Facility at Lanzhou,Hi’Beam-SEE must precisely localize the position at which each heavy ion hitting the integrated circuit(IC)causes SEE.In this study,we propose a fast multi-track location(FML)method based on deep learning to locate the position of each particle track with high speed and accuracy.FML can process a vast amount of data supplied by Hi’Beam-SEE online,revealing sensitive areas in real time.FML is a slot-based object-centric encoder-decoder structure in which each slot can learn the location information of each track in the image.To make the method more accurate for real data,we designed an algorithm to generate a simulated dataset with a distribution similar to that of the real data,which was then used to train the model.Extensive comparison experiments demonstrated that the FML method,which has the best performance on simulated datasets,has high accuracy on real datasets as well.In particular,FML can reach 238 fps and a standard error of 1.6237μm.This study discusses the design and performance of FML.展开更多
This paper proposes a rain considered geophysical model function （GMF）, to be noted as GMF plus Rain. GMF plus Rain is based on the basic raidative transfer model with attenuation and scattering effects of rain on r...This paper proposes a rain considered geophysical model function （GMF）, to be noted as GMF plus Rain. GMF plus Rain is based on the basic raidative transfer model with attenuation and scattering effects of rain on radar signal considered. Combined with the NSCAT2 GMF and the rain correction model, the GMF plus Rain model is used to retrieve the ocean wind vectors from the collocated QuikSCAT and SSM/I rain rate data for typhoon Melor. The resulting wind speed estimates of typhoon Melor show improved agreement with the wind fields derived from the best track analysis of Japan Meteorological Agency （JMA）. The results imply that compared with the GMF model, the GMF plus Rain model can improve the precision of wind retrieval under the rain condition. Then, a new general algorithm of locating the eye of typhoon through the normalized radar cross section （NRCS） is proposed. The implementation of this algorithm in the ten QuikSCAT observations of typhoon Melor suggests that this algorithm is effective.展开更多
This paper studies on the Partial Discharge (PD) Locating System based on a mobile array of ultra-high frequency (UHF) antennas and a vehicle-mounted PD locating system is established. The system consists of omni-dire...This paper studies on the Partial Discharge (PD) Locating System based on a mobile array of ultra-high frequency (UHF) antennas and a vehicle-mounted PD locating system is established. The system consists of omni-directional antenna array for receiving UHF PD signals, a pre-processing circuit for signal amplification and filtering and the high- speed acquisition and control unit of PD pulse signals. The developed locating system is able to simultaneously record the PD pulse signals received by the antenna array. By assessing the time difference of arrival (TDOA), the two-dimensional hyperbolic locating model quickly locates the PD source. Based on the software developed by LabVIEW, it is also possible to display, store and further analyze the acquired signals. Through the simulation of PD signals and the locating experiments with the system, it is proved that the PD locating system possesses the features of rapidity and precision in determining the bearing of PD source.展开更多
The two-station positioning system based on time difference and azimuth measurement has measurement redundancy. Therefore, not only can a positioning solution which is completely independent of the baseline length bet...The two-station positioning system based on time difference and azimuth measurement has measurement redundancy. Therefore, not only can a positioning solution which is completely independent of the baseline length between two stations be derived, but also the baseline length can be solved as an unknown quantity. These findings not only enhance the performance of the two-station positioning system, but also provide a design basis for the construction of a self-organizing dynamic intelligent positioning system.展开更多
We have developed a type of L-shaped single-component geophone array as a single station(L-array station)for surface microseismic monitoring.The L-array station consists of two orthogonal sensor arrays,each being a li...We have developed a type of L-shaped single-component geophone array as a single station(L-array station)for surface microseismic monitoring.The L-array station consists of two orthogonal sensor arrays,each being a linear array of single-component sensors.L-array stations can be used to accurately estimate the polarization of first arrivals without amplitude picking.In a synthetic example,we first use segmentally iterative ray tracing(SIRT)method and forward model to calculate the travel time and polarization of first arrivals at a set of L-array stations.Then,for each L-array station,the relative delay times of first arrivals along sensor arrays are used to estimate the polarization vector.The small errors in estimated polarization vectors show the reliability and robustness of polarization estimation based on L-array stations.We then use reverse-time ray-tracing(RTRT)method to locate the source position based on estimated polarizations at a set of L-array stations.Very small errors in inverted source location and origin time indicate the great potential of L-array stations for source localization applications in surface microseismic monitoring.展开更多
Radio-frequency(RF)breakdown analysis and location are critical for successful development of high-gradient traveling-wave(TW)accelerators,especially those expected to generate high-intensity,high-power beams.Compared...Radio-frequency(RF)breakdown analysis and location are critical for successful development of high-gradient traveling-wave(TW)accelerators,especially those expected to generate high-intensity,high-power beams.Compared with commonly used schemes involving dedicated devices or complicated techniques,a convenient approach for breakdown locating based on transmission line(TL)theory offers advantages in the typical constant-gradient TW-accelerating structure.To deliver such an approach,an equivalent TL model has been constructed to equate the TW-accelerating structure based on the fun-damental theory of the TL transient response in the time domain.An equivalence relationship between the TW-accelerating structure and the TL model has been established via analytical derivations associated with grid charts and verified by TL circuit simulations.Furthermore,to validate the proposed fault-locating method in practical applications,an elaborate analysis via such a method has been conducted for the recoverable RF-breakdown phenomena observed at an existing prototype of a TW-accelerating-structure-based beam injector constructed at the Huazhong University of Science and Technology.In addition,further considerations and discussion for extending the applications of the proposed method have been given.This breakdown-locating approach involving the transient response in the framework of TL theory can be a conceivable supple-ment to existing methods,facilitating solution to construction problems at an affordable cost.展开更多
Due to high interferometric coherence in the Nevada region,Interferometric Synthetic Aperture Radar(InSAR)phase stacking is capable of mapping coseismic signals from the 27 January 1999,M w 4.8 Frenchman Flat earthqua...Due to high interferometric coherence in the Nevada region,Interferometric Synthetic Aperture Radar(InSAR)phase stacking is capable of mapping coseismic signals from the 27 January 1999,M w 4.8 Frenchman Flat earthquake.This is one of the smallest earthquakes yet studied using InSAR with line-of-sight displacements as small as~1.5 cm.Modelling the event as dislocation in an elastic half space suggests that the fault centroid was located at(115.96°W,36.81°N)with a precision of 0.2~0.3 km(1σ)at a depth of 3.4±0.2 km.Despite the dense local seismic network in southern Nevada,differences as large as 2~5 km were observed between our InSAR earthquake location and those estimated from seismic data.The InSAR-derived magnitude appeared to be greater than that from seismic data,which is consistent with other studies,and believed to be due to the relatively long time interval of InSAR data.展开更多
基金Supported by the National Basic Research Program of China(2012CB025904)Zhengzhou Shengda University of Economics,Business and Management(SD-YB2025085)。
文摘Gauss radial basis functions(GRBF)are frequently employed in data fitting and machine learning.Their linear independence property can theoretically guarantee the avoidance of data redundancy.In this paper,one of the main contributions is proving this property using linear algebra instead of profound knowledge.This makes it easy to read and understand this fundamental fact.The proof of linear independence of a set of Gauss functions relies on the constructing method for one-dimensional space and on the deducing method for higher dimensions.Additionally,under the condition of preserving the same moments between the original function and interpolating function,both the interpolating existence and uniqueness are proven for GRBF in one-dimensional space.The final work demonstrates the application of the GRBF method to locate lunar olivine.By combining preprocessed data using GRBF with the removing envelope curve method,a program is created to find the position of lunar olivine based on spectrum data,and the numerical experiment shows that it is an effective scheme.
基金supported by the National High Technology Research and Development Program of China(863 Program)(No.2012AA7031015)
文摘This paper investigates the problem of target position estimation with a single-observer passive coherent location（PCL） system. An approach that combines angle with time difference of arrival（ATDOA） is used to estimate the location of a target. Compared with the TDOA-only method which needs two steps, the proposed method estimates the target position more directly. The constrained total least squares（CTLS） technique is applied in this approach. It achieves the Cramer–Rao lower bound（CRLB） when the parameter measurements are subject to small Gaussian-distributed errors. Performance analysis and the CRLB of this approach are also studied. Theory verifies that the ATDOA method gets a lower CRLB than the TDOA-only method with the same TDOA measuring error. It can also be seen that the position of the target affects estimating precision.At the same time, the locations of transmitters affect the precision and its gradient direction.Compared with the TDOA, the ATDOA method can obtain more precise target position estimation.Furthermore, the proposed method accomplishes target position estimation with a single transmitter,while the TDOA-only method needs at least four transmitters to get the target position. Furthermore,the transmitters＇ position errors also affect precision of estimation regularly.
基金Aeronautical Science Foundation of China (2007ZC53030)
文摘As an important parameter in the single airborne passive locating system, the rate of phase difference change contains range information of the radio emitter. Taking single carrier sine pulse signals as an example, this article illustrates the principle of passive location through measurement of rates of phase difference change and analyzes the structure of measurement errors. On the basis of the Cramér-Rao lower bound (CRLB), an algorithm associated with time-chips is proposed to determine the rates of pha...
基金This work is supported by the National Natural Science Foundation of China(40674044)the Special Foundation for Basic Professional Scientific Research (DQJB06A02)
文摘The intersection method is one of the basic approaches for locating earthquakes and is not only robust but also efficient. However, its location accuracy is not high, especially for focal depth because the velocity model used for the conventional intersection method is based on homogeneous or laterally homogeneous media, which is too simple. In order to improve the accuracy, we have modified the existing intersection method. In the modified approach, the earthquake loci are not assumed to be circular or hyperbolic and calculation accuracy is improved using a minimum traveltime tree algorithm for tracing rays. The numerical model shows that the modified method can locate earthquakes in complex velocity models.
文摘A conventional non-computerized numerical control （CNC） machine is updated by mounting a six degree-of-free （DOF） parallel mechanism on it, thus obtaining a new CNC one. The structure of this CNC milling machine is introduced, and the workpiece locating system and the post processing system of the cutter location （CL） data file are analyzed. The new machine has advantages of low costs, simple structure, good rigidity, and high precision. It is easy to be transformed and used to process the workpiece with a complex surface.
基金supported by the Specialized Research Fund for the Doctoral Program of Higher Education (No.20130132110023)by the National Natural Science Foundation of China (Nos.41230318,41074077)
文摘A velocity model is an important factor influencing microseismic event locations. We re- view the velocity modeling and inversion techniques for locating microseismic events in exploration for unconventional oil and gas reservoirs. We first describe the geological and geophysical characteristics of reservoir formations related to hydraulic fracturing in heterogeneity, anisotropy, and variability, then discuss the influences of velocity estimation, anisotropy model, and their time-lapse changes on the accuracy in determining microseismic event locations, and then survey some typical methods for building velocity models in locating event locations. We conclude that the three tangled physical attributes of reservoirs make microseismic monitoring very challenging. The uncertainties in velocity model and ignoring its anisotropies and its variations in hydraulic fracturing can cause systematic mislocations of microseismie events which are unacceptable in microseismic monitoring. So, we propose some potential ways for building accurate velocity models.
基金supported by National Basic Research Program of China (No.2010CB731800)
文摘Since GPS signals are unavailable for indoor navigation, current research mainly focuses on vision-based locating with a single mark. An obvious disadvantage with this approach is that locating will fail when the mark cannot be seen. The use of multiple marks can solve this problem. However, the extra process to design and identify different marks will significantly increase system complexity. In this paper, a novel vision-based locating method is proposed by using marks with feature points arranged in a radial shape. The feature points of the marks consist of inner points and outer points. The positions of the inner points are the same in all marks, while the positions of the outer points are different in different marks. Unlike traditional camera locating methods （the PnP methods）, the proposed method can calculate the camera location and the positions of the outer points simultaneously. Then the calculation results of the positions of the outer points are used to identify the mark. This method can make navigation with multiple marks more efficient. Simulations and real world experiments are carried out, and their results show that the proposed method is fast, accurate and robust to noise.
基金supported by the National Natural Science Foundation of China(Nos.61473307,61304120)
文摘Drogue recognition and 3D locating is a key problem during the docking phase of the autonomous aerial refueling （AAR）. To solve this problem, a novel and effective method based on monocular vision is presented in this paper. Firstly, by employing computer vision with red-ring-shape feature, a drogue detection and recognition algorithm is proposed to guarantee safety and ensure the robustness to the drogue diversity and the changes in environmental condi- tions, without using a set of infrared light emitting diodes （LEDs） on the parachute part of the dro- gue. Secondly, considering camera lens distortion, a monocular vision measurement algorithm for drogue 3D locating is designed to ensure the accuracy and real-time performance of the system, with the drogue attitude provided. Finally, experiments are conducted to demonstrate the effective- ness of the proposed method. Experimental results show the performances of the entire system in contrast with other methods, which validates that the proposed method can recognize and locate the drogue three dimensionally, rapidly and precisely.
文摘Technology of passive location has broad prospects in applications. In this paper, the method using the phase rate of change for the single observer passive location is introduced based on existing methods. One can obtain the direction of the target with phase information of two orthogonal interferometers on the observer and the radial distance with the corresponding phase rate of change. Then the target can be located with high speed and precision. A locating approach is given when the flying posture of t...
基金the National Key R&D Program of China (No. 2017YFC0906800)the National Natural Science Foundation of China (Nos. 21672166, 21635006, 21721005, 21728802) for the financial support
文摘In addition to the canonical nucleobases, a variety of chemical modifications have been identified presence in nucleic acids. These modifications have been demonstrated to involve in regulating the spatiotemporal expression of genes. Up to date, over 150 types of chemical modifications have been found existence in nucleic acids. Understanding the functional roles of modifications relies on deciphering the location information of modifications in nucleic acids. Analytical methods for studying nucleic acid modifications have greatly advanced in the last decade. To locate the modifications in nucleic acids, various mass spectrometry (MS)-based analytical strategies have been established. Recent progress in next-generation sequencing (NGS) in conjugation with immunoprecipitation, chemical reaction, enzyme-mediated mutation, or nanomaterials offer genome-wide or transcriptome-wide mapping of modifications, which greatly revolutionize the field of epigenetic modifications. Herein, we reviewed and summarized the established methods and the breakthrough of the techniques for locating modifications in nucleic acids. In addition, we discussed the principles, applications, advantages and drawbacks of these methods. We believe that with the rapid advancement of techniques and methods,the functions of nucleic acid modifications will be fully understood in the future.
基金Project(2006BAK04B03) supported by the National Basic Research Program of ChinaProject(CX2009B053) supported by Innovation Foundation for Postgraduate Students of Hunan Province,ChinaProject(2009ybfz08) supported by the Doctoral Dissertation of Central South University,China
文摘in order to achieve a more efficient way to accurately detect the position of the fire source of spontaneous combustion underground mine, a simple fire source locating method, based on infrared scanning system which can determine the point where the highest temperature on the surface of igniting ores occurs, was proposed. First, the differential equations that describe heat flow in ore body were presented and the relationship between the surface temperature distribution and the depth and intensity of inner fire source was established with a relatively simple heat transfer model. With the solution of equation, the expression of the relationship between the surface temperature distribution and the inner fire source was deduced and the mathematical-physical model of heat transfer process was set up. Then, with the model, visualization of fire source on the basis of MATLAB simulation platform was realized. The results show that： 1） within 10 m, when the detecting depth is less than 2 m, the temperature perturbation on ores surface can change rapidly, and then slowly; after 4 m, in contrast, it changes very little, and is even close to zero at 10 m; 2） When it is close to self-ignition duration and the detective depths are 2, 5 and 10 m, respectively, the maximum temperature differences are correspondingly 0.5, 0.04 and 0.005 ℃ in the scope of 1 m×1 m; under the same condition, the maximum temperature differences are 1.391, 0.136 and 0.018 ℃, respectively, in the scope of 2 m×2 m. Therefore, this system can be used to measure the temperature differences on the surface of ore body and determine the highest temperature point directly. Also, it is possible to determine the depth of fire source and its intensity by locating method of fire source indirectly.
基金supported by the National Natural Science Foundation of China(No.51375396)the Shaanxi Science and Technology Innovation Project Plan,China(No.2016KTCQ01-50)
文摘Fixture locating layout has a direct and influential impact on aeronautical thin-walled component(ATWC)manufacturing quality.The purpose is to develop a topological optimization method for ATWC fixture locating layout to minimize the manufacturing deformation.Firstly,a topological optimization model that takes the stiffness of ATWC as the objective function and the volume of the locating structure as the constraint is established.Secondly,ATWC and the locating structure are regarded as an integrated entity,and the variable-density method based topological optimization approach is adopted for the optimization of the locating structure using ABAQUS topology optimization module(ATOM).Thirdly,through a subsequent model reconstruction referring to the obtained topological structure,the optimal fixture locating layout is achieved.Finally,a case study is conducted to verify the proposed method and the comparison results with firefly algorithm(FA)coupled with finite element analysis(FEA)indicate that the number and positions of the locators for ATWC can be optimized simultaneously and successfully by the proposed topological optimization model.
基金supported by the National Natural Science Foundation of China (Nos.U2032209,11975292,12222512)the National Key Research and Development Program of China (2021YFA1601300)+2 种基金the CAS“Light of West China”Programthe CAS Pioneer Hundred Talent Programthe Guangdong Major Project of Basic and Applied Basic Research (No.2020B0301030008)。
文摘To improve the efficiency and accuracy of single-event effect(SEE)research at the Heavy Ion Research Facility at Lanzhou,Hi’Beam-SEE must precisely localize the position at which each heavy ion hitting the integrated circuit(IC)causes SEE.In this study,we propose a fast multi-track location(FML)method based on deep learning to locate the position of each particle track with high speed and accuracy.FML can process a vast amount of data supplied by Hi’Beam-SEE online,revealing sensitive areas in real time.FML is a slot-based object-centric encoder-decoder structure in which each slot can learn the location information of each track in the image.To make the method more accurate for real data,we designed an algorithm to generate a simulated dataset with a distribution similar to that of the real data,which was then used to train the model.Extensive comparison experiments demonstrated that the FML method,which has the best performance on simulated datasets,has high accuracy on real datasets as well.In particular,FML can reach 238 fps and a standard error of 1.6237μm.This study discusses the design and performance of FML.
基金The National Natural Science Foundation of China under contract Nos 41005029,41105012 and 41105063the National Public Benefit (Meteorology) Research Foundation of China under contract No.GYHY201106004
文摘This paper proposes a rain considered geophysical model function （GMF）, to be noted as GMF plus Rain. GMF plus Rain is based on the basic raidative transfer model with attenuation and scattering effects of rain on radar signal considered. Combined with the NSCAT2 GMF and the rain correction model, the GMF plus Rain model is used to retrieve the ocean wind vectors from the collocated QuikSCAT and SSM/I rain rate data for typhoon Melor. The resulting wind speed estimates of typhoon Melor show improved agreement with the wind fields derived from the best track analysis of Japan Meteorological Agency （JMA）. The results imply that compared with the GMF model, the GMF plus Rain model can improve the precision of wind retrieval under the rain condition. Then, a new general algorithm of locating the eye of typhoon through the normalized radar cross section （NRCS） is proposed. The implementation of this algorithm in the ten QuikSCAT observations of typhoon Melor suggests that this algorithm is effective.
文摘This paper studies on the Partial Discharge (PD) Locating System based on a mobile array of ultra-high frequency (UHF) antennas and a vehicle-mounted PD locating system is established. The system consists of omni-directional antenna array for receiving UHF PD signals, a pre-processing circuit for signal amplification and filtering and the high- speed acquisition and control unit of PD pulse signals. The developed locating system is able to simultaneously record the PD pulse signals received by the antenna array. By assessing the time difference of arrival (TDOA), the two-dimensional hyperbolic locating model quickly locates the PD source. Based on the software developed by LabVIEW, it is also possible to display, store and further analyze the acquired signals. Through the simulation of PD signals and the locating experiments with the system, it is proved that the PD locating system possesses the features of rapidity and precision in determining the bearing of PD source.
文摘The two-station positioning system based on time difference and azimuth measurement has measurement redundancy. Therefore, not only can a positioning solution which is completely independent of the baseline length between two stations be derived, but also the baseline length can be solved as an unknown quantity. These findings not only enhance the performance of the two-station positioning system, but also provide a design basis for the construction of a self-organizing dynamic intelligent positioning system.
基金Project(KYCX17_0500)supported by the Postgraduate Research&Practice Innovation Program of Jiangsu Province,ChinaProjects(2013/B17020664X,2014B17614)supported by the Fundamental Research Funds for the Central Universities,China+2 种基金Project(41174043)supported by the National Natural Science Foundation of ChinaProject supported by the Funds from China Scholarship Council(CSC)Project(487237)supported by the NSERC Discovery Grant for LIU Qin-ya。
文摘We have developed a type of L-shaped single-component geophone array as a single station(L-array station)for surface microseismic monitoring.The L-array station consists of two orthogonal sensor arrays,each being a linear array of single-component sensors.L-array stations can be used to accurately estimate the polarization of first arrivals without amplitude picking.In a synthetic example,we first use segmentally iterative ray tracing(SIRT)method and forward model to calculate the travel time and polarization of first arrivals at a set of L-array stations.Then,for each L-array station,the relative delay times of first arrivals along sensor arrays are used to estimate the polarization vector.The small errors in estimated polarization vectors show the reliability and robustness of polarization estimation based on L-array stations.We then use reverse-time ray-tracing(RTRT)method to locate the source position based on estimated polarizations at a set of L-array stations.Very small errors in inverted source location and origin time indicate the great potential of L-array stations for source localization applications in surface microseismic monitoring.
基金supported by the National Natural Science Foundation of China(No.11905074).
文摘Radio-frequency(RF)breakdown analysis and location are critical for successful development of high-gradient traveling-wave(TW)accelerators,especially those expected to generate high-intensity,high-power beams.Compared with commonly used schemes involving dedicated devices or complicated techniques,a convenient approach for breakdown locating based on transmission line(TL)theory offers advantages in the typical constant-gradient TW-accelerating structure.To deliver such an approach,an equivalent TL model has been constructed to equate the TW-accelerating structure based on the fun-damental theory of the TL transient response in the time domain.An equivalence relationship between the TW-accelerating structure and the TL model has been established via analytical derivations associated with grid charts and verified by TL circuit simulations.Furthermore,to validate the proposed fault-locating method in practical applications,an elaborate analysis via such a method has been conducted for the recoverable RF-breakdown phenomena observed at an existing prototype of a TW-accelerating-structure-based beam injector constructed at the Huazhong University of Science and Technology.In addition,further considerations and discussion for extending the applications of the proposed method have been given.This breakdown-locating approach involving the transient response in the framework of TL theory can be a conceivable supple-ment to existing methods,facilitating solution to construction problems at an affordable cost.
基金Shaanxi Province Science and Technology Innovation Team(No.2021TD-51)ESA-MOST DRAGON-5 Project(No.59339)。
文摘Due to high interferometric coherence in the Nevada region,Interferometric Synthetic Aperture Radar(InSAR)phase stacking is capable of mapping coseismic signals from the 27 January 1999,M w 4.8 Frenchman Flat earthquake.This is one of the smallest earthquakes yet studied using InSAR with line-of-sight displacements as small as~1.5 cm.Modelling the event as dislocation in an elastic half space suggests that the fault centroid was located at(115.96°W,36.81°N)with a precision of 0.2~0.3 km(1σ)at a depth of 3.4±0.2 km.Despite the dense local seismic network in southern Nevada,differences as large as 2~5 km were observed between our InSAR earthquake location and those estimated from seismic data.The InSAR-derived magnitude appeared to be greater than that from seismic data,which is consistent with other studies,and believed to be due to the relatively long time interval of InSAR data.
