LEADSFON(XIAMEN)TEXTILE TECH CO.,LTD.is a manufacturer of knitting circular machines.Since 2002,the company has served as an ODM and supporting partner for the Italian brand"PILOTELLI".In 2014,LEADSFON offic...LEADSFON(XIAMEN)TEXTILE TECH CO.,LTD.is a manufacturer of knitting circular machines.Since 2002,the company has served as an ODM and supporting partner for the Italian brand"PILOTELLI".In 2014,LEADSFON officially acquired PILOTELLI,integrating advanced Italian technology into its core operations.展开更多
In recent years,deep learning has been introduced into the field of Single-pixel imaging(SPI),garnering significant attention.However,conventional networks still exhibit limitations in preserving image details.To addr...In recent years,deep learning has been introduced into the field of Single-pixel imaging(SPI),garnering significant attention.However,conventional networks still exhibit limitations in preserving image details.To address this issue,we integrate Large Kernel Convolution(LKconv)into the U-Net framework,proposing an enhanced network structure named U-LKconv network,which significantly enhances the capability to recover image details even under low sampling conditions.展开更多
The synthesis of diamond single crystal in the Fe64Ni36-C system with h-BN additive is investigated at pressure 6.5 GPa and temperature range of 1300-1400℃. The color of the obtained diamond crystals translates from ...The synthesis of diamond single crystal in the Fe64Ni36-C system with h-BN additive is investigated at pressure 6.5 GPa and temperature range of 1300-1400℃. The color of the obtained diamond crystals translates from yellow to dark green with increasing the h-BN addition. Fourier-transform infrared （FTIR） results indicate that sp2 hybridization B-N-B and B-N structures generate when the additive content reaches a certain value in the system. The two peaks are located at 745 and 1425cm-1, respectively. Fhrthermore, the FTIR characteristic peak resulting from nitrogen pairs is noticed and it tends to vanish when the h-BN addition reaches 1.1 wt%. Furthermore, Raman peak of the synthesized diamond shifts down to a lower wavenumber with increasing the h-BN ~ddition content in the synthesis system.展开更多
Multi-component active materials are widely used for organic electronic devices, with every component contributing complementary and synergistic optoelectronic functions. Mixing these components generally leads to low...Multi-component active materials are widely used for organic electronic devices, with every component contributing complementary and synergistic optoelectronic functions. Mixing these components generally leads to lowered crystallinity and weakened charge transport. Therefore, preparing the active materials without substantially disrupting the crystalline lattice is highly desired. Here, we show that crystallization of TIPS-pentacene from solutions in the presence of fluorescent nanofibers of a perylene bisimide derivative （PBI） leads to formation of composites with nanoflber vip incorporated in the crystal host. In spite of the binary composite structure, the TIPS-pentacene maintains the single- crystalline nature. As a result, the incorporation of the PB1 vip introduces additional fluorescence function but does not significantly reduce the charge transport property of the TIPS-pentacene host, exhibiting field-effect mobility as high as 3.34 cm^2 V^-1 s^-1 even though 26.4% of the channel area is taken over by the vip. As such, this work provides a facile approach toward high-performance multifunctional organic electronic materials.展开更多
The current figure of merit to evaluate Single Molecule Magnet(SMM)performance is the blocking temperature(T_(B)).The best SMMs show T_(B) values close to liquid nitrogen boiling point(77 K)while their Orbach effectiv...The current figure of merit to evaluate Single Molecule Magnet(SMM)performance is the blocking temperature(T_(B)).The best SMMs show T_(B) values close to liquid nitrogen boiling point(77 K)while their Orbach effective demagnetization barriers(U_(eff))are significantly larger,exceeding 2000 K in some cases.As current high performance SMMs approach the axial limit,new strategies to suppress demagnetization by vibrational tuning have been suggested.In this article,we analyse a set of 17 current high performance SMMs to identify which demagnetization mechanism is limiting the blocking temperature.For the best systems(T_(B)>50 K),the limiting mechanism is thermally assisted tunneling and the blocking temperature will depend on the exponential parameters Ueff and τ_(0).Strategies focusing on Raman(vibrational)suppression are expected to have a limited effect for this group.In contrast,systems with lower blocking temperatures(T_(B)<50 K)would benefit from such strategies,although they are not expected to surpass current record T_(B) values.The Orbach limit for the blocking temperature can be conveniently estimated using ab initio CASSCF methods.Finally,a recent proposal for a hypothetical high performance SMM is analysed under the presented framework,showing its potential to improve record blocking temperatures.展开更多
Tumor cell-intrinsic programmed death-ligand 1(PD-L1)signals mediate tumor initiation,progression and metastasis,but their effects in ameloblastoma(AM)have not been reported.In this comprehensive study,we observed mar...Tumor cell-intrinsic programmed death-ligand 1(PD-L1)signals mediate tumor initiation,progression and metastasis,but their effects in ameloblastoma(AM)have not been reported.In this comprehensive study,we observed marked upregulation of PD-L1 in AM tissues and revealed the robust correlation between elevated PD-L1 expression and increased tumor growth and recurrence rates.Notably,we found that PD-L1 overexpression markedly increased self-renewal capacity and promoted tumorigenic processes and invasion in hTERT^(+)-AM cells,whereas genetic ablation of PD-L1 exerted opposing inhibitory effects.By performing highresolution single-cell profiling and thorough immunohistochemical analyses in AM patients,we delineated the intricate cellular landscape and elucidated the mechanisms underlying the aggressive phenotype and unfavorable prognosis of these tumors.Our findings revealed that hTERT^(+)-AM cells with upregulated PD-L1 expression exhibit increased proliferative potential and stem-like attributes and undergo partial epithelial-mesenchymal transition.This phenotypic shift is induced by the activation of the PI3KAKT-mTOR signaling axis;thus,this study revealed a crucial regulatory mechanism that fuels tumor growth and recurrence.Importantly,targeted inhibition of the PD-L1-PI3K-AKT-mTOR signaling axis significantly suppressed the growth of AM patientderived tumor organoids,highlighting the potential of PD-L1 blockade as a promising therapeutic approach for AM.展开更多
A new modification of borosilicate datolite,CaBSiO_(4)(OH),has been discovered using synchrotron-based in situ high-pressure single-crystal X-ray diffraction.The phase transition from low(I)to high(II)pressure modific...A new modification of borosilicate datolite,CaBSiO_(4)(OH),has been discovered using synchrotron-based in situ high-pressure single-crystal X-ray diffraction.The phase transition from low(I)to high(II)pressure modification is isosymmetric and occurs between 27 and 33 GPa.展开更多
Recently,the research team led by Prof.Chen Guang(陈光)at the Engineering Research Center of Materials Behavior and Design,Ministry of Education,Nanjing University of Science and Technology,successfully manufactured a...Recently,the research team led by Prof.Chen Guang(陈光)at the Engineering Research Center of Materials Behavior and Design,Ministry of Education,Nanjing University of Science and Technology,successfully manufactured a new kind of high-temperature polysynthetic twinned(PST)TiAl single展开更多
We demonstrated stable midinfrared(MIR) optical frequency comb at the 3.0 μm region with difference frequency generation pumped by a high power, Er-doped, ultrashort pulse fiber laser system. A soliton mode-locked161...We demonstrated stable midinfrared(MIR) optical frequency comb at the 3.0 μm region with difference frequency generation pumped by a high power, Er-doped, ultrashort pulse fiber laser system. A soliton mode-locked161 MHz high repetition rate fiber laser using a single wall carbon nanotube was fabricated. The output pulse was amplified in an Er-doped single mode fiber amplifier, and a 1.1–2.2 μm wideband supercontinuum(SC) with an average power of 205 m W was generated in highly nonlinear fiber. The spectrogram of the generated SC was examined both experimentally and numerically. The generated SC was focused into a nonlinear crystal, and stable generation of MIR comb around the 3 μm wavelength region was realized.展开更多
High-power single-frequency fiber lasers with diffraction-limited spots are indispensable for a wide range of photonic applications and are particularly in advanced detection and sensing technologies.However,the simul...High-power single-frequency fiber lasers with diffraction-limited spots are indispensable for a wide range of photonic applications and are particularly in advanced detection and sensing technologies.However,the simultaneous achievement of kilowatt-level output power and diffraction-limited beam quality has remained elusive in all reported single-frequency fiber laser systems to date,primarily due to limitations imposed by the stimulated Brillouin scattering(SBS)effect and transverse mode instability(TMI)effect.In this study,we demonstrate the design and manufacturing of an ultra-low numerical aperture(NA)functional Yb-doped fiber featuring a bat-type refractive index distribution,specifically engineered for single-frequency laser amplification.In the fabrication,we implemented multiple chelate gas filling and particle deposition iterations,leading to an active fiber with a bat-type refractive index distribution.The unique capabilities of this large mode area and high-order modes leakage fiber(HOMLF)were demonstrated by stably amplifying the single-frequency laser with more than one kilowatt output power and near single mode beam quality(M_(x)^(2)=1.10,M_(x)^(2)=1.18)for the first time.This fiber design advances the leap forward in single-frequency fiber lasers,which could contribute as a novel and efficient laser amplification technique for the next generation of gravitational wave detection systems.展开更多
The single high-dose application of biochar to increase rice yield has been well reported.However,limited information is available about the long-term effects of increasing rice yield and soil fertility.This study was...The single high-dose application of biochar to increase rice yield has been well reported.However,limited information is available about the long-term effects of increasing rice yield and soil fertility.This study was designed to perform a 6-year field experiment to unveil the rice yield with time due to various biochar application strategies.Moreover,an alternative strategy of the Annual Low dose biochar application(AL,8×35%=2.8 t ha^(−1))was also conducted to make a comparison with the High Single dose(HS,22.5 t ha^(−1)),and annual Rice Straw(RS,8 t ha^(−1))amendment to investigate the effects on annual rice yield attributes and soil nutrient concentrations.Results showed that the rice yield in AL with a lower biochar application exceeded that of HS significantly(p<0.05)in the 6th experimental year.The rice yield increased by 14.3%in RS,10.9%in AL,and 4.2%in HS.The unexpectedly higher rice yield in AL than HS resulted from enhanced soil total carbon(TC),pH,and available Ca.However,compared to AL,liable carbon fraction increased by 33.7%in HS,while refractory carbon fraction dropped by 22.3%.Likewise,biochar characterization showed that more oxygen functional groups existed in HS than in AL.Decreasing inert organic carbon pools due to the constant degradation of the aromatic part of biochar in HS led to a lower soil TC than AL,even with a higher amount of biochar application.Likewise,the annual depletion lowered the soil pH and available Ca declination in HS.Based on the obtained results,this study suggested AL as a promising strategy to enhance rice productivity,soil nutrient enrichment,and carbon sequestration in the paddy ecosystem.展开更多
文摘LEADSFON(XIAMEN)TEXTILE TECH CO.,LTD.is a manufacturer of knitting circular machines.Since 2002,the company has served as an ODM and supporting partner for the Italian brand"PILOTELLI".In 2014,LEADSFON officially acquired PILOTELLI,integrating advanced Italian technology into its core operations.
文摘In recent years,deep learning has been introduced into the field of Single-pixel imaging(SPI),garnering significant attention.However,conventional networks still exhibit limitations in preserving image details.To address this issue,we integrate Large Kernel Convolution(LKconv)into the U-Net framework,proposing an enhanced network structure named U-LKconv network,which significantly enhances the capability to recover image details even under low sampling conditions.
基金Supported by the National Natural Science Foundation of China under Grant No 51172089the Natural Science Foundation of Guizhou Province Education Department under Grant No KY[2013]183the Natural Science Foundation of Guizhou Province Science and Technology Agency under Grant Nos LH[2015]7232 and LH[2015]7228
文摘The synthesis of diamond single crystal in the Fe64Ni36-C system with h-BN additive is investigated at pressure 6.5 GPa and temperature range of 1300-1400℃. The color of the obtained diamond crystals translates from yellow to dark green with increasing the h-BN addition. Fourier-transform infrared （FTIR） results indicate that sp2 hybridization B-N-B and B-N structures generate when the additive content reaches a certain value in the system. The two peaks are located at 745 and 1425cm-1, respectively. Fhrthermore, the FTIR characteristic peak resulting from nitrogen pairs is noticed and it tends to vanish when the h-BN addition reaches 1.1 wt%. Furthermore, Raman peak of the synthesized diamond shifts down to a lower wavenumber with increasing the h-BN ~ddition content in the synthesis system.
基金supported by the 973 Program (No. 2014CB643503)National Natural Science Foundation of China (Nos. 51625304, 51373150, 51461165301, 51573055)the Open Foundation Project of the State Key Lab of Silicon Materials (No. SKL2017-08)
文摘Multi-component active materials are widely used for organic electronic devices, with every component contributing complementary and synergistic optoelectronic functions. Mixing these components generally leads to lowered crystallinity and weakened charge transport. Therefore, preparing the active materials without substantially disrupting the crystalline lattice is highly desired. Here, we show that crystallization of TIPS-pentacene from solutions in the presence of fluorescent nanofibers of a perylene bisimide derivative （PBI） leads to formation of composites with nanoflber vip incorporated in the crystal host. In spite of the binary composite structure, the TIPS-pentacene maintains the single- crystalline nature. As a result, the incorporation of the PB1 vip introduces additional fluorescence function but does not significantly reduce the charge transport property of the TIPS-pentacene host, exhibiting field-effect mobility as high as 3.34 cm^2 V^-1 s^-1 even though 26.4% of the channel area is taken over by the vip. As such, this work provides a facile approach toward high-performance multifunctional organic electronic materials.
基金FONDECYT Regular 1170524 for financial supportNational Agency for Research and Development(ANID),PhD Scholarships No.21170520 and 21180269,respectively+1 种基金Powered@NLHPC:This research was partially supported by the supercomputing infrastructure of the NLHPC(ECM-02)Universidad de Santiago de Chile,Usach,Project DICYT code 021942AP-PAP.
文摘The current figure of merit to evaluate Single Molecule Magnet(SMM)performance is the blocking temperature(T_(B)).The best SMMs show T_(B) values close to liquid nitrogen boiling point(77 K)while their Orbach effective demagnetization barriers(U_(eff))are significantly larger,exceeding 2000 K in some cases.As current high performance SMMs approach the axial limit,new strategies to suppress demagnetization by vibrational tuning have been suggested.In this article,we analyse a set of 17 current high performance SMMs to identify which demagnetization mechanism is limiting the blocking temperature.For the best systems(T_(B)>50 K),the limiting mechanism is thermally assisted tunneling and the blocking temperature will depend on the exponential parameters Ueff and τ_(0).Strategies focusing on Raman(vibrational)suppression are expected to have a limited effect for this group.In contrast,systems with lower blocking temperatures(T_(B)<50 K)would benefit from such strategies,although they are not expected to surpass current record T_(B) values.The Orbach limit for the blocking temperature can be conveniently estimated using ab initio CASSCF methods.Finally,a recent proposal for a hypothetical high performance SMM is analysed under the presented framework,showing its potential to improve record blocking temperatures.
基金supported by the postdoctoral fellowship program of CPSF(GZC20241270)the China Postdoctoral Science Foundation(2024M762496).
文摘Tumor cell-intrinsic programmed death-ligand 1(PD-L1)signals mediate tumor initiation,progression and metastasis,but their effects in ameloblastoma(AM)have not been reported.In this comprehensive study,we observed marked upregulation of PD-L1 in AM tissues and revealed the robust correlation between elevated PD-L1 expression and increased tumor growth and recurrence rates.Notably,we found that PD-L1 overexpression markedly increased self-renewal capacity and promoted tumorigenic processes and invasion in hTERT^(+)-AM cells,whereas genetic ablation of PD-L1 exerted opposing inhibitory effects.By performing highresolution single-cell profiling and thorough immunohistochemical analyses in AM patients,we delineated the intricate cellular landscape and elucidated the mechanisms underlying the aggressive phenotype and unfavorable prognosis of these tumors.Our findings revealed that hTERT^(+)-AM cells with upregulated PD-L1 expression exhibit increased proliferative potential and stem-like attributes and undergo partial epithelial-mesenchymal transition.This phenotypic shift is induced by the activation of the PI3KAKT-mTOR signaling axis;thus,this study revealed a crucial regulatory mechanism that fuels tumor growth and recurrence.Importantly,targeted inhibition of the PD-L1-PI3K-AKT-mTOR signaling axis significantly suppressed the growth of AM patientderived tumor organoids,highlighting the potential of PD-L1 blockade as a promising therapeutic approach for AM.
基金supported by the Russlian Foundation for Basic Research(grant 17-05-01027)(to SVK)by the People Programme(Marie Curie Actions)of the European Union's Seventh Framework Programme FP7/2007-2013/under the REA grant agreement PIRSES-GA-2013-610547-TAMER(for LAG and SVK).Wethank Professor I.V.Pekov(Moscow State)。
文摘A new modification of borosilicate datolite,CaBSiO_(4)(OH),has been discovered using synchrotron-based in situ high-pressure single-crystal X-ray diffraction.The phase transition from low(I)to high(II)pressure modification is isosymmetric and occurs between 27 and 33 GPa.
文摘Recently,the research team led by Prof.Chen Guang(陈光)at the Engineering Research Center of Materials Behavior and Design,Ministry of Education,Nanjing University of Science and Technology,successfully manufactured a new kind of high-temperature polysynthetic twinned(PST)TiAl single
基金Japan Science and Technology Agency(JST)Japan Agency for Medical Research and Development(AMED)
文摘We demonstrated stable midinfrared(MIR) optical frequency comb at the 3.0 μm region with difference frequency generation pumped by a high power, Er-doped, ultrashort pulse fiber laser system. A soliton mode-locked161 MHz high repetition rate fiber laser using a single wall carbon nanotube was fabricated. The output pulse was amplified in an Er-doped single mode fiber amplifier, and a 1.1–2.2 μm wideband supercontinuum(SC) with an average power of 205 m W was generated in highly nonlinear fiber. The spectrogram of the generated SC was examined both experimentally and numerically. The generated SC was focused into a nonlinear crystal, and stable generation of MIR comb around the 3 μm wavelength region was realized.
基金support from the National Key Research and Development Program of China(2022YFB3606400).
文摘High-power single-frequency fiber lasers with diffraction-limited spots are indispensable for a wide range of photonic applications and are particularly in advanced detection and sensing technologies.However,the simultaneous achievement of kilowatt-level output power and diffraction-limited beam quality has remained elusive in all reported single-frequency fiber laser systems to date,primarily due to limitations imposed by the stimulated Brillouin scattering(SBS)effect and transverse mode instability(TMI)effect.In this study,we demonstrate the design and manufacturing of an ultra-low numerical aperture(NA)functional Yb-doped fiber featuring a bat-type refractive index distribution,specifically engineered for single-frequency laser amplification.In the fabrication,we implemented multiple chelate gas filling and particle deposition iterations,leading to an active fiber with a bat-type refractive index distribution.The unique capabilities of this large mode area and high-order modes leakage fiber(HOMLF)were demonstrated by stably amplifying the single-frequency laser with more than one kilowatt output power and near single mode beam quality(M_(x)^(2)=1.10,M_(x)^(2)=1.18)for the first time.This fiber design advances the leap forward in single-frequency fiber lasers,which could contribute as a novel and efficient laser amplification technique for the next generation of gravitational wave detection systems.
基金National Natural Science Foundation of China[grant numbers 42077032 and 41571241]National Key Technology Research and Development Program of the Ministry of Science and Technology of China[grant number 2015BAC02B01]+1 种基金We gratefully acknowledge the financial support from the China Scholarship Council[grant number 202106320251]Doctoral Rising Star Program of Zhejiang University.
文摘The single high-dose application of biochar to increase rice yield has been well reported.However,limited information is available about the long-term effects of increasing rice yield and soil fertility.This study was designed to perform a 6-year field experiment to unveil the rice yield with time due to various biochar application strategies.Moreover,an alternative strategy of the Annual Low dose biochar application(AL,8×35%=2.8 t ha^(−1))was also conducted to make a comparison with the High Single dose(HS,22.5 t ha^(−1)),and annual Rice Straw(RS,8 t ha^(−1))amendment to investigate the effects on annual rice yield attributes and soil nutrient concentrations.Results showed that the rice yield in AL with a lower biochar application exceeded that of HS significantly(p<0.05)in the 6th experimental year.The rice yield increased by 14.3%in RS,10.9%in AL,and 4.2%in HS.The unexpectedly higher rice yield in AL than HS resulted from enhanced soil total carbon(TC),pH,and available Ca.However,compared to AL,liable carbon fraction increased by 33.7%in HS,while refractory carbon fraction dropped by 22.3%.Likewise,biochar characterization showed that more oxygen functional groups existed in HS than in AL.Decreasing inert organic carbon pools due to the constant degradation of the aromatic part of biochar in HS led to a lower soil TC than AL,even with a higher amount of biochar application.Likewise,the annual depletion lowered the soil pH and available Ca declination in HS.Based on the obtained results,this study suggested AL as a promising strategy to enhance rice productivity,soil nutrient enrichment,and carbon sequestration in the paddy ecosystem.
