Cl^(−)has long been recognized as a potent buffer of membrane potential,with changes in intracellular Cl^(−)concentrations playing crucial physiological roles in cells via electrical signaling.While intracellular seco...Cl^(−)has long been recognized as a potent buffer of membrane potential,with changes in intracellular Cl^(−)concentrations playing crucial physiological roles in cells via electrical signaling.While intracellular second messengers such as Ca^(2+)and cAMP have been extensively studied,Cl^(−)has received comparatively less attention.展开更多
基金supported by the Major Project of Guangzhou National Laboratory(GZNL2023A02001)the Guangdong Science and Technology Department(2023B1212060028)+2 种基金the China Postdoctoral Science Foundation(2024M760657)the Guangzhou Institute of Respiratory Health Open Project Funds provided by China Evergrande Group(2020GIRHHMS13)the Zhongnanshan Medical Foundation of Guangdong Province(ZNSA-2020012).
文摘Cl^(−)has long been recognized as a potent buffer of membrane potential,with changes in intracellular Cl^(−)concentrations playing crucial physiological roles in cells via electrical signaling.While intracellular second messengers such as Ca^(2+)and cAMP have been extensively studied,Cl^(−)has received comparatively less attention.