Colon cancer(CC)laterality(right vs left)is recognized as a key determinant of clinical outcomes and treatment decisions in metastatic CC.Right-sided CC(RCC)often presents in older individuals and is associated with h...Colon cancer(CC)laterality(right vs left)is recognized as a key determinant of clinical outcomes and treatment decisions in metastatic CC.Right-sided CC(RCC)often presents in older individuals and is associated with higher rates of Kirsten rat sarcoma viral oncogene homolog and v-raf murine sarcoma viral oncogene homolog B1 mutations and deficient mismatch repair,leading to microsatellite instability-high status.Left-sided CC typically presents in younger individuals,demonstrates a more favorable prognosis,and is often Kirsten rat sarcoma viral oncogene homolog/neuroblastoma RAS viral oncogene homolog/v-raf murine sarcoma viral oncogene homolog B1 wild-type,making it more responsive to antiepidermal growth factor receptor therapy.RCC typically responds poorly to antiepidermal growth factor receptor agents;however,it may benefit from triplet chemotherapy(5-fluorouracil+leucovorin+oxaliplatin+irinotecan)with or without anti-angiogenic agents.Comprehensive molecular profiling remains challenging in low-resource settings due to limited access to advanced diagnostic tools.This review explores key epidemiological and molecular differences between RCC and left-sided CC.In the absence of complete genomic data,tumor sidedness can be a helpful guide for making treatment decisions.Here,we propose a practical algorithm that integrates basic immunohistochemistry to assess a tumor’s mismatch repair status and laterality,potentially facilitating therapy selection in resource-constrained environments.Recognizing laterality-specific trends in prognosis and treatment response can improve personalized care and outcomes for patients with CC in these environments,highlighting the essential role of cost-effective biomarker strategies.展开更多
Supported cell membrane coatings meet many requirements set to bioactive nanocarriers and materials,provided sidedness and fluidity of the natural membrane are maintained upon coating.However,the properties of a suppo...Supported cell membrane coatings meet many requirements set to bioactive nanocarriers and materials,provided sidedness and fluidity of the natural membrane are maintained upon coating.However,the properties of a support-surface responsible for maintaining correct sidedness and fluidity are unknown.Here,we briefly review the properties of natural membranes and membrane-isolation methods,with focus on the asymmetric distribution of functional groups in natural membranes(sidedness)and the ability of molecules to float across a membrane to form functional domains(fluidity).This review concludes that hydrophilic sugar-residues of glycoproteins in the outer-leaflet of cell membranes direct the more hydrophobic inner-leaflet towards a support-surface to create a correctly-sided membrane coating,regardless of electrostatic double-layer interactions.On positively-charged support-surfaces however,strong,electrostatic double-layer attraction of negatively-charged membranes can impede homogeneous coating.In correctly-sided membrane coatings,fluidity is maintained regardless of whether the surface carries a positive or negative charge.However,membranes are frozen on positively-charged,highly-curved,small nanoparticles and localized nanoscopic structures on a support-surface.This leaves an unsupported membrane coating in between nanostructures on planar support-surfaces that is in dual-sided contact with its aqueous environment,yielding enhanced fluidity in membrane coatings on nanostructured,planar support-surfaces as compared with smooth ones.展开更多
Background:Colorectal liver metastasis(CRLM)exhibits highly heterogeneity,with clinically and molecularly defined subgroups that differ in their prognosis.The aim of this study is to explore whether left-sided tumors ...Background:Colorectal liver metastasis(CRLM)exhibits highly heterogeneity,with clinically and molecularly defined subgroups that differ in their prognosis.The aim of this study is to explore whether left-sided tumors is clinically and gnomically distinct from right-sided tumors in CRLM.Methods:This retrospective study included 1,307 patients who underwent primary tumor and metastases resection at three academic centers in China from January 1,2012,to December 31,2020.Propensity score matching with 1:1 ratio matching was performed.The prognostic impact of tumor sidedness was determined after stratifying by the KRAS mutational status.Moreover,whole-exome sequencing(WES)of 200 liver tumor tissues were performed to describe the heterogeneity across the analysis of somatic and germline profiles.Results:The median follow-up was 68 months.Matching yielded 481 pairs of patients.Compared to right-sided CRLM,left-sided patients experienced with better 5-year overall survival(OS)in surgery responsiveness,with a 14.6 lower risk of death[hazard ratio(HR),1.36,95%confidence interval(CI),1.10-1.69,P=0.004].Interaction between tumor sidedness and KRAS status was statistically significant:left-sidedness was associated with better prognosis among KRAS wild-type patients(HR 1.71;95%CI:1.20-2.45;P=0.003),but not among KRAS mutated-type patients.Integrated molecular analyses showed that right-sided tumors more frequently harbored TP53,APC,KRAS,and BRAF alterations,and identified a critical role of KRAS mutation in correlation with their survival differences.Higher pathogenic germline variants were identified in the right-sided tumors compared with left-sided tumors(29.3%vs.15.5%,P=0.03).Conclusions:We demonstrated that the prognostic impacts of tumor sidedness in CRLM is restricted patients with KRAS wild-type tumors.Tumor sidedness displays considerable clinical and molecular heterogeneity that may associate with their therapy benefits and prognosis.展开更多
On February 21,China Institute of International Studies (CIIS) released the special research report"China-Russia Relations in the New Era."Assistant Minister of Foreign Affairs Liu Bin and Russian Ambassador...On February 21,China Institute of International Studies (CIIS) released the special research report"China-Russia Relations in the New Era."Assistant Minister of Foreign Affairs Liu Bin and Russian Ambassador to China Igor Morgulov attended the release conference and delivered speeches.CIIS President Chen Bo presided over the event and introduced the main content of the report.展开更多
A recent subgroup analysis of the TRIBE trial suggested that FOLFOXIRI plus bevacizumab may be a preferred option for the first-line treatment of only right-sided metastatic colorectal cancer(mCRC), regardless of RAS ...A recent subgroup analysis of the TRIBE trial suggested that FOLFOXIRI plus bevacizumab may be a preferred option for the first-line treatment of only right-sided metastatic colorectal cancer(mCRC), regardless of RAS or BRAF status. Our subanalysis of a phase Ⅱ trial of the FOLFOXIRI triplet regimen plus bevacizumab in patients with mCRC who had RAS mutant tumors showed that tumor shrinkage was better and the duration of treatment was longer in patients with leftsided tumors than in those with right-sided tumors, leading to a higher rate of conversion to surgery in mCRC patients with left-sided tumors. The early and deep responses to the triplet-regimen in patients with left-sided tumors might facilitate conversion treatment resulting in favorable survival. Our data suggest that the FOLFOXIRI plus bevacizumab might be a promising treatment for left-sided mCRC involving RAS mutant tumors.展开更多
Aim of the study is to comprehensively review the latest trends in laparoscopic complete mesocolic excision(CME) with central vascular ligation(CVL) for the multimodal management of right colon cancer. Historical and ...Aim of the study is to comprehensively review the latest trends in laparoscopic complete mesocolic excision(CME) with central vascular ligation(CVL) for the multimodal management of right colon cancer. Historical and up-to-date anatomo-embryological concepts are analyzed in detail,focusing on the latest studies of the mesenteric organ,its dissection by mesofascial and retrofascial cleavage planes,and questioning the need for a new terminology in colonic resections. The rationale behind Laparoscopic CME with CVL is thoroughly investigated and explained. Attention is paid to the current surgical techniques and the quality of the surgical specimen,yielded through mesocolic,intramesocolic and muscularis propria plane of surgery. We evaluate the impact on long term oncologic outcome in terms of local recurrence,overall and disease-free survival,according to the plane of resection achieved. Conclusions are drawn on the basis of the available evidence,which suggests a pivotal role of laparoscopic CME with CVL in the multimodal management of right sided colonic cancer: performed in the right mesocolic plane of resection,laparoscopic CME with CVL demonstrates better oncologic results when compared to standard non-mesocolic planes of surgery,with all the advantages of laparoscopic techniques,both in faster recovery and better immunological response. The importance of minimally invasive mesoresectional surgery is thus stressed and highlighted as the new frontier for a modern laparoscopic total right mesocolectomy.展开更多
Cholecystectomy is a common procedure.Abnormalities in the anatomy of the biliary system are common but an abnormal location of the gallbladder is much rarer.Despite frequent pre-operative imaging,the aberrant locatio...Cholecystectomy is a common procedure.Abnormalities in the anatomy of the biliary system are common but an abnormal location of the gallbladder is much rarer.Despite frequent pre-operative imaging,the aberrant location of the gallbladder is commonly discovered at surgery.This article presents a case of a patient with the gallbladder located to the left of the falciform ligament in the absence of situs inversus totalis that presented with right upper quadrant pain.A laparoscopic cholecystectomy was performed and it was noted that the cystic duct originated from the right side.The presence of a left sided gall bladder is often associated with various biliary,portal venous and other anomalies that might lead to intra-operative injuries.The spectrum of unusual positions and anatomical gallbladder abnormalities is reviewed in order to facilitate elective and emergent cholecystectomy as well as other hepatobiliary procedures.With proper identification of the anatomy,minimally invasive approaches are still considered safe.展开更多
Dear Editor,This letter deals with the stabilization of Lurie networked control systems with network-induced delays(NID).By constructing a twosided looped Lyapunov functional,a sufficient condition is derived to ensur...Dear Editor,This letter deals with the stabilization of Lurie networked control systems with network-induced delays(NID).By constructing a twosided looped Lyapunov functional,a sufficient condition is derived to ensure the absolute stability of the resultant closed-loop system under a state feedback controller.Then,based on this condition,a cone complementary linearisation(CCL)iterative algorithm is presented to design state feedback controller.It is shown via a numerical example that the proposed method can deliver less conservative results as well as fewer iterations if compared with existing ones.展开更多
In this paper, a plate shape perception technique based on quasi-distributed fiber Bragg grating(FBG) array and space surface reconstruction algorithm is proposed. Firstly, in order to make curvature continuous, the b...In this paper, a plate shape perception technique based on quasi-distributed fiber Bragg grating(FBG) array and space surface reconstruction algorithm is proposed. Firstly, in order to make curvature continuous, the bicubic plane interpolation algorithm is studied. Then, taking the simulated satellite bulkhead structure as the research object, we research the space surface reconstruction algorithm based on orthogonal curvature and coordinate transformation(translation and rotation). Finally, a four-sided fixed plate deformation monitoring system based on quasi-distributed FBG sensors network and surface reconstruction algorithm is built. Many experiments are conducted to verify the reliability and accuracy of the algorithm. The proposed algorithm provides a new method for three-dimensional reconstruction of spacecraft structure.展开更多
Tc, Jc and Rs properties of large area double sided YBCO thin films deposited on LaAlO3 substrates by direct current sputtering were reported.Film thickness of the obtained thin films is over 300 nm, Tc > 90 K; Rs ...Tc, Jc and Rs properties of large area double sided YBCO thin films deposited on LaAlO3 substrates by direct current sputtering were reported.Film thickness of the obtained thin films is over 300 nm, Tc > 90 K; Rs can be as low as less than 1.0 mΩ(77 K, 10 GHz).Homogenousity of the properties around the plane was studied.Under the measnous distributions.Influences of substrate temperature and Ar and O2 pressures on properties of the double-sided thin films were discussed.展开更多
0 IntroductionLet L = ab be a non-closed smooth arc oriented from a to b, t∈ L, t≠a,b, be the fixed point, andf(t) ∈H. (L) . The usual Hadamard principal value is defined asAbout properties and applications of sing...0 IntroductionLet L = ab be a non-closed smooth arc oriented from a to b, t∈ L, t≠a,b, be the fixed point, andf(t) ∈H. (L) . The usual Hadamard principal value is defined asAbout properties and applications of singular integals of high order were investigated by many authors([1],[2],[3] etc. ) In 1987, the concepts of Hadamard principal value at one-side for singular integralsof high order and the rules of their differentiation are introduced [4]. In this paper we established the rulesof substitution of variable for one-sided Hadamard principal value of singular integrals of high order, andthen, we gave some applications in evaluation of real definite integrals.展开更多
The following equations are basic forms of C-K equation (which is simplified in the following as singu-lar integral equations with convolution, that is C-K equations):where a,b,a_j,b_j are known constants or known fun...The following equations are basic forms of C-K equation (which is simplified in the following as singu-lar integral equations with convolution, that is C-K equations):where a,b,a_j,b_j are known constants or known functions, and find its solution f L_P(R), {0} or {α,β}.There were rather complete investigations on the method of solution for equations of Cauchy type aswell as integral equations of convolution type. But there is not investigation to the C-K equations, nodoubt, such that is important.展开更多
The presence of the appendix in an inguinal hernia sac has been referred to as Amyand’s hernia.Vermiform appendix located in an external hernia sac is not an uncommon condition,and the incidence of these cases is app...The presence of the appendix in an inguinal hernia sac has been referred to as Amyand’s hernia.Vermiform appendix located in an external hernia sac is not an uncommon condition,and the incidence of these cases is approximately 1%.In Amyand’s hernias,appendices are frequently found in the hernia sac;but an incarceration particularly on the left side is a very unusual sight.In this report we present 32-year-old male with Amyand’s hernia on the left side.展开更多
By designing the ordered structure on the key physical dimensions,metamaterial can obtain extraordinary physical properties.The method gives transparent conductive absorbing metamaterial with broadband and high absorp...By designing the ordered structure on the key physical dimensions,metamaterial can obtain extraordinary physical properties.The method gives transparent conductive absorbing metamaterial with broadband and high absorptivity.In this paper,a kind of absorbing metamaterial with indium tin oxide(ITO)glass substrate is designed.The design method of double-sided etched an open loop and linear metamaterial periodic structures is adopted.The thickness of the absorbing metamaterial is 2.5 mm.The research shows that the working bandwidth is between 8.9 GHz and 17.4 GHz,the absorption rate is 90%,and the transmittance of visible light is 85% on average.The absorbing metamaterial has wide application value to solve the problem of visualization and absorption characteristics.展开更多
Triangular fibrocartilage complex injuries are common in amateur and professional sports.These injuries are mainly caused by acute or chronic repetitive axial loads on the wrist,particularly on the ulnar side and in a...Triangular fibrocartilage complex injuries are common in amateur and professional sports.These injuries are mainly caused by acute or chronic repetitive axial loads on the wrist,particularly on the ulnar side and in association with rotations or radial/ulnar deviations.In order to treat professional athletes,a detailed specific knowledge of the pathology is needed.Moreover,the clinician should fully understand the specific and unique environment and needs of the athletes,their priorities and goals,the type of sport,the time of the season,and the position played.An early diagnosis and appropriate management with the quickest possible recovery time are the uppermost goals for both the athlete and the surgeon.A compromise between conservative vs surgical indications,athletes’needs and expectations,and financial implications should be achieved.Arthroscopic procedures should be timely planned when indicated as they could allow early diagnosis and treatment at the same time.Conservative measures are often used as first line treatment when possible.Peripheral lesions are treated by arthroscopic repair,whilst central lesions are treated by arthroscopic debridement.Further procedures(such as the Wafer procedure,ulnar osteotomies,etc.)have specific indications and great implications with regard to rehabilitation.展开更多
970392 A study on senile cerebral infarction andmemorial impairment. ZHANG Shigui(张世贵), et al.Shandong Liqu People’s Hosp, Linqu, 262600. Chin JNerv & Ment Dis 1997; 23(2): 68-70. Objective: The relationship b...970392 A study on senile cerebral infarction andmemorial impairment. ZHANG Shigui(张世贵), et al.Shandong Liqu People’s Hosp, Linqu, 262600. Chin JNerv & Ment Dis 1997; 23(2): 68-70. Objective: The relationship between senile cerebralinfarction(CI) and memorial impairment was studied.展开更多
In this paper,the definitions of fuzzy regular subsemigroup and fuzzy left(right,intra-)regular sub-semigroup in semigroups are introduced.Some characterizations of them are given.Proposition 2.1.A fuzzy set A in a se...In this paper,the definitions of fuzzy regular subsemigroup and fuzzy left(right,intra-)regular sub-semigroup in semigroups are introduced.Some characterizations of them are given.Proposition 2.1.A fuzzy set A in a semigroup S is a fuzzy subsemigroup iff for any λ∈[0,1],if A_λ={x∈S|A(x)≥λ}≠ ,then A_λ is a subsemigroup of S.Proposition 2.2.A fuzzy set A in a semigroup S is a fuzzy left(right)ideal iff for any λ∈(0,1],if A={x∈S|A(x)展开更多
1.Double-sided role of vibration and shaking Removing vibration and shaking is a pivotal engineering task,which is showcased,for instance,in spacecraft attitude control systems that ensure a precise three-dimensional ...1.Double-sided role of vibration and shaking Removing vibration and shaking is a pivotal engineering task,which is showcased,for instance,in spacecraft attitude control systems that ensure a precise three-dimensional orientation.Vibration or shaking,such as precession caused by external torque,nutation stemming from off-axis angular momentum,and wobbling due to geometric misalignment,necessitate active and passive damping mechanisms.This principle extends beyond spacecraft to centrifugation techniques,pivotal not only in washing machines but also in a spectrum of biomedical apparatuses used for isolating cells and organelles and separating DNA and proteins.展开更多
文摘Colon cancer(CC)laterality(right vs left)is recognized as a key determinant of clinical outcomes and treatment decisions in metastatic CC.Right-sided CC(RCC)often presents in older individuals and is associated with higher rates of Kirsten rat sarcoma viral oncogene homolog and v-raf murine sarcoma viral oncogene homolog B1 mutations and deficient mismatch repair,leading to microsatellite instability-high status.Left-sided CC typically presents in younger individuals,demonstrates a more favorable prognosis,and is often Kirsten rat sarcoma viral oncogene homolog/neuroblastoma RAS viral oncogene homolog/v-raf murine sarcoma viral oncogene homolog B1 wild-type,making it more responsive to antiepidermal growth factor receptor therapy.RCC typically responds poorly to antiepidermal growth factor receptor agents;however,it may benefit from triplet chemotherapy(5-fluorouracil+leucovorin+oxaliplatin+irinotecan)with or without anti-angiogenic agents.Comprehensive molecular profiling remains challenging in low-resource settings due to limited access to advanced diagnostic tools.This review explores key epidemiological and molecular differences between RCC and left-sided CC.In the absence of complete genomic data,tumor sidedness can be a helpful guide for making treatment decisions.Here,we propose a practical algorithm that integrates basic immunohistochemistry to assess a tumor’s mismatch repair status and laterality,potentially facilitating therapy selection in resource-constrained environments.Recognizing laterality-specific trends in prognosis and treatment response can improve personalized care and outcomes for patients with CC in these environments,highlighting the essential role of cost-effective biomarker strategies.
基金financially supported by the National Key Research and Development Program of China(2017YFE0131700)the National Natural Science Foundation of China(52293383)the Soochow University,the Nankai University,and UMCG,Groningen,The Netherlands.
文摘Supported cell membrane coatings meet many requirements set to bioactive nanocarriers and materials,provided sidedness and fluidity of the natural membrane are maintained upon coating.However,the properties of a support-surface responsible for maintaining correct sidedness and fluidity are unknown.Here,we briefly review the properties of natural membranes and membrane-isolation methods,with focus on the asymmetric distribution of functional groups in natural membranes(sidedness)and the ability of molecules to float across a membrane to form functional domains(fluidity).This review concludes that hydrophilic sugar-residues of glycoproteins in the outer-leaflet of cell membranes direct the more hydrophobic inner-leaflet towards a support-surface to create a correctly-sided membrane coating,regardless of electrostatic double-layer interactions.On positively-charged support-surfaces however,strong,electrostatic double-layer attraction of negatively-charged membranes can impede homogeneous coating.In correctly-sided membrane coatings,fluidity is maintained regardless of whether the surface carries a positive or negative charge.However,membranes are frozen on positively-charged,highly-curved,small nanoparticles and localized nanoscopic structures on a support-surface.This leaves an unsupported membrane coating in between nanostructures on planar support-surfaces that is in dual-sided contact with its aqueous environment,yielding enhanced fluidity in membrane coatings on nanostructured,planar support-surfaces as compared with smooth ones.
基金supported by National Natural Science Foundation of China(81874182,M-0334)Natural Science Foundation of Shanghai(22ZR1413300)+2 种基金National Science and Technology Major Project(2017ZX10203204-007-004)Shanghai Municipal Health Bureau(201940043)Shanghai Hospital Development Center(SHDC12019X19).
文摘Background:Colorectal liver metastasis(CRLM)exhibits highly heterogeneity,with clinically and molecularly defined subgroups that differ in their prognosis.The aim of this study is to explore whether left-sided tumors is clinically and gnomically distinct from right-sided tumors in CRLM.Methods:This retrospective study included 1,307 patients who underwent primary tumor and metastases resection at three academic centers in China from January 1,2012,to December 31,2020.Propensity score matching with 1:1 ratio matching was performed.The prognostic impact of tumor sidedness was determined after stratifying by the KRAS mutational status.Moreover,whole-exome sequencing(WES)of 200 liver tumor tissues were performed to describe the heterogeneity across the analysis of somatic and germline profiles.Results:The median follow-up was 68 months.Matching yielded 481 pairs of patients.Compared to right-sided CRLM,left-sided patients experienced with better 5-year overall survival(OS)in surgery responsiveness,with a 14.6 lower risk of death[hazard ratio(HR),1.36,95%confidence interval(CI),1.10-1.69,P=0.004].Interaction between tumor sidedness and KRAS status was statistically significant:left-sidedness was associated with better prognosis among KRAS wild-type patients(HR 1.71;95%CI:1.20-2.45;P=0.003),but not among KRAS mutated-type patients.Integrated molecular analyses showed that right-sided tumors more frequently harbored TP53,APC,KRAS,and BRAF alterations,and identified a critical role of KRAS mutation in correlation with their survival differences.Higher pathogenic germline variants were identified in the right-sided tumors compared with left-sided tumors(29.3%vs.15.5%,P=0.03).Conclusions:We demonstrated that the prognostic impacts of tumor sidedness in CRLM is restricted patients with KRAS wild-type tumors.Tumor sidedness displays considerable clinical and molecular heterogeneity that may associate with their therapy benefits and prognosis.
文摘On February 21,China Institute of International Studies (CIIS) released the special research report"China-Russia Relations in the New Era."Assistant Minister of Foreign Affairs Liu Bin and Russian Ambassador to China Igor Morgulov attended the release conference and delivered speeches.CIIS President Chen Bo presided over the event and introduced the main content of the report.
文摘A recent subgroup analysis of the TRIBE trial suggested that FOLFOXIRI plus bevacizumab may be a preferred option for the first-line treatment of only right-sided metastatic colorectal cancer(mCRC), regardless of RAS or BRAF status. Our subanalysis of a phase Ⅱ trial of the FOLFOXIRI triplet regimen plus bevacizumab in patients with mCRC who had RAS mutant tumors showed that tumor shrinkage was better and the duration of treatment was longer in patients with leftsided tumors than in those with right-sided tumors, leading to a higher rate of conversion to surgery in mCRC patients with left-sided tumors. The early and deep responses to the triplet-regimen in patients with left-sided tumors might facilitate conversion treatment resulting in favorable survival. Our data suggest that the FOLFOXIRI plus bevacizumab might be a promising treatment for left-sided mCRC involving RAS mutant tumors.
文摘Aim of the study is to comprehensively review the latest trends in laparoscopic complete mesocolic excision(CME) with central vascular ligation(CVL) for the multimodal management of right colon cancer. Historical and up-to-date anatomo-embryological concepts are analyzed in detail,focusing on the latest studies of the mesenteric organ,its dissection by mesofascial and retrofascial cleavage planes,and questioning the need for a new terminology in colonic resections. The rationale behind Laparoscopic CME with CVL is thoroughly investigated and explained. Attention is paid to the current surgical techniques and the quality of the surgical specimen,yielded through mesocolic,intramesocolic and muscularis propria plane of surgery. We evaluate the impact on long term oncologic outcome in terms of local recurrence,overall and disease-free survival,according to the plane of resection achieved. Conclusions are drawn on the basis of the available evidence,which suggests a pivotal role of laparoscopic CME with CVL in the multimodal management of right sided colonic cancer: performed in the right mesocolic plane of resection,laparoscopic CME with CVL demonstrates better oncologic results when compared to standard non-mesocolic planes of surgery,with all the advantages of laparoscopic techniques,both in faster recovery and better immunological response. The importance of minimally invasive mesoresectional surgery is thus stressed and highlighted as the new frontier for a modern laparoscopic total right mesocolectomy.
文摘Cholecystectomy is a common procedure.Abnormalities in the anatomy of the biliary system are common but an abnormal location of the gallbladder is much rarer.Despite frequent pre-operative imaging,the aberrant location of the gallbladder is commonly discovered at surgery.This article presents a case of a patient with the gallbladder located to the left of the falciform ligament in the absence of situs inversus totalis that presented with right upper quadrant pain.A laparoscopic cholecystectomy was performed and it was noted that the cystic duct originated from the right side.The presence of a left sided gall bladder is often associated with various biliary,portal venous and other anomalies that might lead to intra-operative injuries.The spectrum of unusual positions and anatomical gallbladder abnormalities is reviewed in order to facilitate elective and emergent cholecystectomy as well as other hepatobiliary procedures.With proper identification of the anatomy,minimally invasive approaches are still considered safe.
基金This work was supported by the National Natural Science Foundation of China(62173136)the Natural Science Foundation of Hunan Province(2020JJ2013,2021JJ50047)。
文摘Dear Editor,This letter deals with the stabilization of Lurie networked control systems with network-induced delays(NID).By constructing a twosided looped Lyapunov functional,a sufficient condition is derived to ensure the absolute stability of the resultant closed-loop system under a state feedback controller.Then,based on this condition,a cone complementary linearisation(CCL)iterative algorithm is presented to design state feedback controller.It is shown via a numerical example that the proposed method can deliver less conservative results as well as fewer iterations if compared with existing ones.
基金supported by the National Natural Science Foundation of China(Nos.62073193 and 61873333)the Key Research and Development Plan of Shandong Province(Nos.2019TSLH0301 and 2019GHZ004)the Natural Science Foundation of Shandong Province(No.ZR2021MF041)。
文摘In this paper, a plate shape perception technique based on quasi-distributed fiber Bragg grating(FBG) array and space surface reconstruction algorithm is proposed. Firstly, in order to make curvature continuous, the bicubic plane interpolation algorithm is studied. Then, taking the simulated satellite bulkhead structure as the research object, we research the space surface reconstruction algorithm based on orthogonal curvature and coordinate transformation(translation and rotation). Finally, a four-sided fixed plate deformation monitoring system based on quasi-distributed FBG sensors network and surface reconstruction algorithm is built. Many experiments are conducted to verify the reliability and accuracy of the algorithm. The proposed algorithm provides a new method for three-dimensional reconstruction of spacecraft structure.
文摘Tc, Jc and Rs properties of large area double sided YBCO thin films deposited on LaAlO3 substrates by direct current sputtering were reported.Film thickness of the obtained thin films is over 300 nm, Tc > 90 K; Rs can be as low as less than 1.0 mΩ(77 K, 10 GHz).Homogenousity of the properties around the plane was studied.Under the measnous distributions.Influences of substrate temperature and Ar and O2 pressures on properties of the double-sided thin films were discussed.
文摘0 IntroductionLet L = ab be a non-closed smooth arc oriented from a to b, t∈ L, t≠a,b, be the fixed point, andf(t) ∈H. (L) . The usual Hadamard principal value is defined asAbout properties and applications of singular integals of high order were investigated by many authors([1],[2],[3] etc. ) In 1987, the concepts of Hadamard principal value at one-side for singular integralsof high order and the rules of their differentiation are introduced [4]. In this paper we established the rulesof substitution of variable for one-sided Hadamard principal value of singular integrals of high order, andthen, we gave some applications in evaluation of real definite integrals.
文摘The following equations are basic forms of C-K equation (which is simplified in the following as singu-lar integral equations with convolution, that is C-K equations):where a,b,a_j,b_j are known constants or known functions, and find its solution f L_P(R), {0} or {α,β}.There were rather complete investigations on the method of solution for equations of Cauchy type aswell as integral equations of convolution type. But there is not investigation to the C-K equations, nodoubt, such that is important.
文摘The presence of the appendix in an inguinal hernia sac has been referred to as Amyand’s hernia.Vermiform appendix located in an external hernia sac is not an uncommon condition,and the incidence of these cases is approximately 1%.In Amyand’s hernias,appendices are frequently found in the hernia sac;but an incarceration particularly on the left side is a very unusual sight.In this report we present 32-year-old male with Amyand’s hernia on the left side.
基金supported by the Shanxi Province Youth Science and Technology Research Foundation(No.201901D211577)the Shanxi Province Natural Science Foundation(No.201901D111001)。
文摘By designing the ordered structure on the key physical dimensions,metamaterial can obtain extraordinary physical properties.The method gives transparent conductive absorbing metamaterial with broadband and high absorptivity.In this paper,a kind of absorbing metamaterial with indium tin oxide(ITO)glass substrate is designed.The design method of double-sided etched an open loop and linear metamaterial periodic structures is adopted.The thickness of the absorbing metamaterial is 2.5 mm.The research shows that the working bandwidth is between 8.9 GHz and 17.4 GHz,the absorption rate is 90%,and the transmittance of visible light is 85% on average.The absorbing metamaterial has wide application value to solve the problem of visualization and absorption characteristics.
文摘Triangular fibrocartilage complex injuries are common in amateur and professional sports.These injuries are mainly caused by acute or chronic repetitive axial loads on the wrist,particularly on the ulnar side and in association with rotations or radial/ulnar deviations.In order to treat professional athletes,a detailed specific knowledge of the pathology is needed.Moreover,the clinician should fully understand the specific and unique environment and needs of the athletes,their priorities and goals,the type of sport,the time of the season,and the position played.An early diagnosis and appropriate management with the quickest possible recovery time are the uppermost goals for both the athlete and the surgeon.A compromise between conservative vs surgical indications,athletes’needs and expectations,and financial implications should be achieved.Arthroscopic procedures should be timely planned when indicated as they could allow early diagnosis and treatment at the same time.Conservative measures are often used as first line treatment when possible.Peripheral lesions are treated by arthroscopic repair,whilst central lesions are treated by arthroscopic debridement.Further procedures(such as the Wafer procedure,ulnar osteotomies,etc.)have specific indications and great implications with regard to rehabilitation.
文摘970392 A study on senile cerebral infarction andmemorial impairment. ZHANG Shigui(张世贵), et al.Shandong Liqu People’s Hosp, Linqu, 262600. Chin JNerv & Ment Dis 1997; 23(2): 68-70. Objective: The relationship between senile cerebralinfarction(CI) and memorial impairment was studied.
文摘In this paper,the definitions of fuzzy regular subsemigroup and fuzzy left(right,intra-)regular sub-semigroup in semigroups are introduced.Some characterizations of them are given.Proposition 2.1.A fuzzy set A in a semigroup S is a fuzzy subsemigroup iff for any λ∈[0,1],if A_λ={x∈S|A(x)≥λ}≠ ,then A_λ is a subsemigroup of S.Proposition 2.2.A fuzzy set A in a semigroup S is a fuzzy left(right)ideal iff for any λ∈(0,1],if A={x∈S|A(x)
文摘1.Double-sided role of vibration and shaking Removing vibration and shaking is a pivotal engineering task,which is showcased,for instance,in spacecraft attitude control systems that ensure a precise three-dimensional orientation.Vibration or shaking,such as precession caused by external torque,nutation stemming from off-axis angular momentum,and wobbling due to geometric misalignment,necessitate active and passive damping mechanisms.This principle extends beyond spacecraft to centrifugation techniques,pivotal not only in washing machines but also in a spectrum of biomedical apparatuses used for isolating cells and organelles and separating DNA and proteins.
