Objective:To identify the acceptance of the vaccine based on factors influencing the vaccination program and the side effects from vaccinated people.Methods:A cross-sectional online survey of 1529 Bangladeshi adults(...Objective:To identify the acceptance of the vaccine based on factors influencing the vaccination program and the side effects from vaccinated people.Methods:A cross-sectional online survey of 1529 Bangladeshi adults(≥18 years)was conducted between 17 April,2021 and 26 April,2021.Statistical analysis of the data included Chi-square test and multinomial logistic regression analysis.Results:In total,67.04%of the participants were willing to accept a COVID-19 vaccine,and 45.00%of them in our study had already received.Overall Bangladeshi people were more likely to accept COVID-19 vaccine if the vaccine reduces risk of infectious disease and has no associated health risk after receiving it.Among the respondents,religions,education level,living area(urban),belif that vaccines protect against infectious diseases and vaccines do not have health-related risk and vaccination was significantly associated with the acceptance of COVID-19 vaccines.Conversely,people’s perception on development of natural immunity rather than receiving vaccines was also positively reflected.More than half(57.41%)reported minor side effects such as fever,muscle pain and headache after getting vaccine shots.Conclusions:This study revealed that the acceptance rate was influenced by socio-demographic and health-related characteristics and people are not afraid of this vaccine if they faced minor side effects after receiving it.These findings might help the government and policymakers of Bangladesh to implement necessary steps to accomplish this vaccination program effectively.展开更多
Objective: The aim of the study was to observe the clinical effects of Shenqi Fuzheng injection decreasing sideeffects of chemotherapy for patients with ovarian epithelial cancer. Methods: The 36 cases of ovarian epit...Objective: The aim of the study was to observe the clinical effects of Shenqi Fuzheng injection decreasing sideeffects of chemotherapy for patients with ovarian epithelial cancer. Methods: The 36 cases of ovarian epithelial cancer in The Third Affiliated Hospital of SUN Yat-sen University(Guangzhou, China) from June 2010 to June 2013, were randomly divided into the study group and the control group. The study group contained 18 cases using Shenqi Fuzheng injection combined with TP(Taxol + Carboplatin/cisplatin) chemotherapy, and the control group contained 18 cases only using TP chemotherapy without Shenqi Fuzheng injection. During and after chemotherapy, the side-effects and therapy effects were observed. Results: The grade II of nausea and vomit were less in the study group than that in the control group, which was significantly different(P < 0.05). But there were no significantly differences in grade I of nausea and vomit between the two groups(P > 0.05). There was less degree of decrease of lymphocyte in the study group than that in the control group, which was significantly different(P < 0.05). But between two groups, there were no significant differences in the drop of white blood cells and red blood cells, the incidence of allergic reaction, liver and renal functions, nerve lesion and phalacrosis(P > 0.05). There was no significant difference in chemotherapy effect between the two groups(P > 0.05). Conclusion: Shenqi Fuzheng injection can in some degree relieve the side effects of TP chemotherapy for the patients with ovarian epithelial cancer, including relieving nausea and vomiting, protecting lymphocytes, and has no conflict effect on chemotherapy efficacy.展开更多
To observe the efficacy of Baofuxin for treatment of bleeding side effect induced by IUD. Method The study is a multi-center trial. The subjects were randomly allocated into two groups, Baofuxin group (90 cases) and...To observe the efficacy of Baofuxin for treatment of bleeding side effect induced by IUD. Method The study is a multi-center trial. The subjects were randomly allocated into two groups, Baofuxin group (90 cases) and Indomethacin group (90 cases). In the Baofuxin group, the subjects took the medicine on the first day of menses, once a bag, twice a day for 10 days. In the Indomethacin group,only one capsule was taken once a time, twice a day for 7 days. The treatment was given for three menstrual cycles. The subjects were asked to record their bleeding/spotting by using menstrual diary card not only during the treatment cycles but also during the three months previous and after the treatment cycles. The menstrual profile was analyzed by using MDSv2. 3 program that was provided by WHO. Results Within each 90-day reference period of treatment and post-treatment cycles, the number of bleeding/spotting days decreased obviously and bleeding/spotting free days were greatly increased. Both medicines have little effect on number of episode of bleeding/spotting. The subjects who thought the treatment were highly effective were 81. 1% in the Baofuxin group and 56.2% in the Indomethacin group respectively (P <0.01). Conclusion Both Bat,fuxin and indomethacin are highly effective on treatment of bleeding side effect induced by IUD, but Baofuxin had longer effects and was more acceptable.展开更多
目的:探讨扶正口服汤联合奥沙利铂及卡培他滨(Oxaliplatin and Capecitabine,XELOX)化疗方案对结直肠癌患者卡氏功能状态评分(Karnofsky performance status score,KPS)及毒副反应发生率的影响。方法:前瞻性选取2020年5月至2024年5月我...目的:探讨扶正口服汤联合奥沙利铂及卡培他滨(Oxaliplatin and Capecitabine,XELOX)化疗方案对结直肠癌患者卡氏功能状态评分(Karnofsky performance status score,KPS)及毒副反应发生率的影响。方法:前瞻性选取2020年5月至2024年5月我院收治的122例结直肠癌患作为研究对象。根据随机信封法将所有患者分为研究组和对照组,各61例。对照组采用XELOX化疗方案治疗,研究组在对照组的基础上加用扶正口服汤治疗,两组均持续治疗8个疗程。比较两组临床疗效,并于治疗前后采用中医证候积分及KPS评分评估两组临床症状及生存质量;比较两组的免疫功能(CD3^(+)、CD4^(+)/CD8^(+)、NK细胞、CD8^(+)),以及两组治疗期间的毒副反应发生情况。结果:研究组疾病控制率明显高于对照组(P<0.05)。治疗后,研究组中医证候积分、CD8^(+)、Ⅰ-Ⅱ级的毒副反应发生率明显低于对照组;研究组KPS评分、CD3^(+)、CD4^(+)/CD8^(+)、NK明显高于对照组(P<0.05)。结论:扶正口服汤联合XELOX化疗方案可有效提高结直肠癌患者疗效,改善免疫功能及KPS评分,减轻化疗毒副作用。展开更多
文摘Objective:To identify the acceptance of the vaccine based on factors influencing the vaccination program and the side effects from vaccinated people.Methods:A cross-sectional online survey of 1529 Bangladeshi adults(≥18 years)was conducted between 17 April,2021 and 26 April,2021.Statistical analysis of the data included Chi-square test and multinomial logistic regression analysis.Results:In total,67.04%of the participants were willing to accept a COVID-19 vaccine,and 45.00%of them in our study had already received.Overall Bangladeshi people were more likely to accept COVID-19 vaccine if the vaccine reduces risk of infectious disease and has no associated health risk after receiving it.Among the respondents,religions,education level,living area(urban),belif that vaccines protect against infectious diseases and vaccines do not have health-related risk and vaccination was significantly associated with the acceptance of COVID-19 vaccines.Conversely,people’s perception on development of natural immunity rather than receiving vaccines was also positively reflected.More than half(57.41%)reported minor side effects such as fever,muscle pain and headache after getting vaccine shots.Conclusions:This study revealed that the acceptance rate was influenced by socio-demographic and health-related characteristics and people are not afraid of this vaccine if they faced minor side effects after receiving it.These findings might help the government and policymakers of Bangladesh to implement necessary steps to accomplish this vaccination program effectively.
基金Supported by a grant of Chinese Medicine Scientific Research of Guangdong Province(No.2010113)
文摘Objective: The aim of the study was to observe the clinical effects of Shenqi Fuzheng injection decreasing sideeffects of chemotherapy for patients with ovarian epithelial cancer. Methods: The 36 cases of ovarian epithelial cancer in The Third Affiliated Hospital of SUN Yat-sen University(Guangzhou, China) from June 2010 to June 2013, were randomly divided into the study group and the control group. The study group contained 18 cases using Shenqi Fuzheng injection combined with TP(Taxol + Carboplatin/cisplatin) chemotherapy, and the control group contained 18 cases only using TP chemotherapy without Shenqi Fuzheng injection. During and after chemotherapy, the side-effects and therapy effects were observed. Results: The grade II of nausea and vomit were less in the study group than that in the control group, which was significantly different(P < 0.05). But there were no significantly differences in grade I of nausea and vomit between the two groups(P > 0.05). There was less degree of decrease of lymphocyte in the study group than that in the control group, which was significantly different(P < 0.05). But between two groups, there were no significant differences in the drop of white blood cells and red blood cells, the incidence of allergic reaction, liver and renal functions, nerve lesion and phalacrosis(P > 0.05). There was no significant difference in chemotherapy effect between the two groups(P > 0.05). Conclusion: Shenqi Fuzheng injection can in some degree relieve the side effects of TP chemotherapy for the patients with ovarian epithelial cancer, including relieving nausea and vomiting, protecting lymphocytes, and has no conflict effect on chemotherapy efficacy.
文摘To observe the efficacy of Baofuxin for treatment of bleeding side effect induced by IUD. Method The study is a multi-center trial. The subjects were randomly allocated into two groups, Baofuxin group (90 cases) and Indomethacin group (90 cases). In the Baofuxin group, the subjects took the medicine on the first day of menses, once a bag, twice a day for 10 days. In the Indomethacin group,only one capsule was taken once a time, twice a day for 7 days. The treatment was given for three menstrual cycles. The subjects were asked to record their bleeding/spotting by using menstrual diary card not only during the treatment cycles but also during the three months previous and after the treatment cycles. The menstrual profile was analyzed by using MDSv2. 3 program that was provided by WHO. Results Within each 90-day reference period of treatment and post-treatment cycles, the number of bleeding/spotting days decreased obviously and bleeding/spotting free days were greatly increased. Both medicines have little effect on number of episode of bleeding/spotting. The subjects who thought the treatment were highly effective were 81. 1% in the Baofuxin group and 56.2% in the Indomethacin group respectively (P <0.01). Conclusion Both Bat,fuxin and indomethacin are highly effective on treatment of bleeding side effect induced by IUD, but Baofuxin had longer effects and was more acceptable.
文摘目的:探讨扶正口服汤联合奥沙利铂及卡培他滨(Oxaliplatin and Capecitabine,XELOX)化疗方案对结直肠癌患者卡氏功能状态评分(Karnofsky performance status score,KPS)及毒副反应发生率的影响。方法:前瞻性选取2020年5月至2024年5月我院收治的122例结直肠癌患作为研究对象。根据随机信封法将所有患者分为研究组和对照组,各61例。对照组采用XELOX化疗方案治疗,研究组在对照组的基础上加用扶正口服汤治疗,两组均持续治疗8个疗程。比较两组临床疗效,并于治疗前后采用中医证候积分及KPS评分评估两组临床症状及生存质量;比较两组的免疫功能(CD3^(+)、CD4^(+)/CD8^(+)、NK细胞、CD8^(+)),以及两组治疗期间的毒副反应发生情况。结果:研究组疾病控制率明显高于对照组(P<0.05)。治疗后,研究组中医证候积分、CD8^(+)、Ⅰ-Ⅱ级的毒副反应发生率明显低于对照组;研究组KPS评分、CD3^(+)、CD4^(+)/CD8^(+)、NK明显高于对照组(P<0.05)。结论:扶正口服汤联合XELOX化疗方案可有效提高结直肠癌患者疗效,改善免疫功能及KPS评分,减轻化疗毒副作用。
