The efficiency and mechanism of an active control device ＂＇Spark Jet＂ and its application in shock-induced separation control are studied using large-eddy simulation in this paper. The base flow is the interaction ...The efficiency and mechanism of an active control device ＂＇Spark Jet＂ and its application in shock-induced separation control are studied using large-eddy simulation in this paper. The base flow is the interaction of an oblique shock-wave generated by 8° wedge and a spatially-developing Ma = 2.3 turbulent boundary layer. The Reynolds number based on the incoming flow property and the boundary layer displacement thickness at the impinging point without shock-wave is 20000. The detailed numerical approaches were presented. The inflow turbulence was generated using the digital filter method to avoid artificial temporal or streamwise periodicity. The , merical results including velocity profile, Reynolds stress profile, skin friction, and wall pressure were sys- tematically validated against the available wind tunnel particle image velocimetry （PIV） measure- ments of the same flow condition. Further study on the control of flow separation due to the strong shock-viscous interaction using an active control actuator ＂＇Spark Jet＇＂ was conducted. The single-pulsed characteristic of the device was obtained and compared with the experiment. Both instantaneous and time-averaged flow fields have shown that the jet flow issuing from the actuator cavity enhances the flow mixing inside the boundary layer, making the boundary layer more resis- tant to flow separation. Skin friction coefficient distribution shows that the separation bubble length is reduced by about 35% with control exerted.展开更多
Transition prediction is of great importance for the design of long distance flying vehicles. It starts from the problem of receptivity, i.e., how external disturbances trigger instability waves in the boundary layer....Transition prediction is of great importance for the design of long distance flying vehicles. It starts from the problem of receptivity, i.e., how external disturbances trigger instability waves in the boundary layer. For super/hypersonic boundary layers, the external disturbances first interact with the shock ahead of the flying vehicles before entering the boundary layer. Since direct numerical simulation （DNS） is the only available tool for its comprehensive and detailed investigation, an important problem arises whether the numerical scheme, especially the shock-capturing method, can faithfully reproduce the interaction of the external disturbances with the shock, which is so far unknown. This paper is aimed to provide the answer. The interaction of weak disturbances with an oblique shock is investigated, which has a known theoretical solution. Numerical simulation using the shock-capturing method is conducted, and results are compared with those given by theoretical analysis, which shows that the adopted numerical method can faithfully reproduce the interaction of weak external disturbances with the shock.展开更多
Stem cell transplantation and low-energy shock-wave therapy （LESWT） have emerged as potential and effective treatment protocols for diabetic erectile dysfunction. During the tracking of transplanted stem cells in di...Stem cell transplantation and low-energy shock-wave therapy （LESWT） have emerged as potential and effective treatment protocols for diabetic erectile dysfunction. During the tracking of transplanted stem cells in diabetic erectile dysfunction models, the number of visible stem cells was rather low and decreased quickly. LESWT could recruit endogenous stem cells to the cavernous body and improve the microenvironment in diabetic cavernous tissue. Thus, we deduced that LESWT might benefit transplanted stem cell survival and improve the effects of stem cell transplantation. In this research, 42 streptozotocin-induced diabetic rats were randomized into four groups： the diabetic group （n = 6）, the LESWT group （n = 6）, the bone marrow-derived mesenchymal stem cell （BMSC） transplantation group （n = 15）, and the combination of LESWT and BMSC transplantation group （n = 15）. One and three days after BMSC transplantation, three rats were randomly chosen to observe the survival numbers of BMSCs in the cavernous body. Four weeks after BMSC transplantation, the following parameters were assessed： the surviving number of transplanted BMSCs in the cavernous tissue, erectile function, real-time polymerase chain reaction, and penile immunohistochemical assessment. Our research found that LESWT favored the survival of transplanted BMSCs in the cavernous body, which might be related to increased stromal cell-derived factor-1 expression and the enhancement of angiogenesis in the diabetic cavernous tissue. The combination of LESWT and BMSC transplantation could improve the erectile function of diabetic erectile function rats more effectively than LESWT or BMSC transplantation performed alone.展开更多
It is of great significance to improve the accuracy of turbulence models in shock-wave/ boundary layer interaction flow. The relationship between the pressure gradient, as well as the shear layer, and the development ...It is of great significance to improve the accuracy of turbulence models in shock-wave/ boundary layer interaction flow. The relationship between the pressure gradient, as well as the shear layer, and the development of turbulent kinetic energy in impinging shock-wave/turbulent bound- ary layer interaction flow at Mach 2.25 is analyzed based on the data of direct numerical simulation （DNS）. It is found that the turbulent kinetic energy is amplified by strong shear in the separation zone and the adverse pressure gradient near the separation point. The pressure gradient was non-dimensionalised with local density, velocity, and viscosity. Spalart Allmaras （S A） model is modified by introducing the non-dimensional pressure gradient into the production term of the eddy viscosity transportation equation. Simulation results show that the production and dissipation of eddy viscosity are strongly enhanced by the modification of S-A model. Compared with DNS and experimental data, the wall pressure and the wall skin friction coefficient as well as the velocity profile of the modified S-A model are obviously improved. Thus it can be concluded that the mod- ification of S-A model with the pressure gradient can improve the predictive accuracy for simulat- ing the shock-wave/turbulent boundary laver interaction.展开更多
The influences of the acoustic impedance and shock strength on the jet formation in shock-heavy gas bubble interaction are numerically studied in this work. The process of a shock interacting with a krypton or a SF6 b...The influences of the acoustic impedance and shock strength on the jet formation in shock-heavy gas bubble interaction are numerically studied in this work. The process of a shock interacting with a krypton or a SF6 bubble is studied by the numerical method VAS2D. As a validation, the experiments of a SF6 bubble accelerated by a planar shock were performed. The results indicate that, due to the mismatch of acoustic impedance, the way of jet formation in heavy gas bubble with different species is diversified under the same initial condition. With respect to the same bubble, the manner of jet formation is also distinctly different under different shock strengths. The disparities of the acoustic impedance result in different effects of shock focusing in the bubble, and different behaviors of shock wave inside and outside the bubble. The analyses of the wave pattern and the pressure variation indicate that the jet formation is closely associated with the pressure perturbation. Moreover, the analy- sis of the vorticity deposition, and comparisons of circulation and baroclinic torque show that the baroclinic vorticity also contributes to the jet formation. It is concluded that the pres- sure perturbation and baroclinic vorticity deposition are the two dominant factors for the jet formation in shock-heavy gas bubble interaction.展开更多
A comprehensive methodology for simulating 2 D dynamic stall at fluctuating freestream is proposed in this paper.2 D CFD simulation of a SC1095 airfoil exposed to a fluctuating freestream of Mach number 0.537±0.2...A comprehensive methodology for simulating 2 D dynamic stall at fluctuating freestream is proposed in this paper.2 D CFD simulation of a SC1095 airfoil exposed to a fluctuating freestream of Mach number 0.537±0.205 and Reynolds number 6.1×10~6(based on the mean Mach number)and undergoing a 10°±10°pitch oscillation with a frequency of 4.25 Hz was conducted.These conditions were selected to be representative of the flow experienced by a helicopter rotor airfoil section in a real-life fast forward flight.Both constant freestream dynamic stall as well as fluctuating freestream dynamic stall simulations were conducted and compared.The methodology was carefully validated with experimental data for both transonic flow and dynamic stall under fluctuating freestream.Overall,the results suggest that the fluctuating freestream alters the dynamic stall mechanism documented for constant freestream in a major way,emphasizing that inclusion of this effect in the prediction of dynamic stall related rotor loads is imperative for rotor performance analysis and blades design.展开更多
A reliable data treatment method is critical for viscosity measurements using the disturbance amplitude damping method of shock waves. In this paper the finite difference method is used to obtain the numerical solutio...A reliable data treatment method is critical for viscosity measurements using the disturbance amplitude damping method of shock waves. In this paper the finite difference method is used to obtain the numerical solutions for the disturbance amplitude damping behaviour of the sinusoidal shock front in a flyer-impact experiment. The disturbance amplitude damping curves are used to depict the numerical solutions of viscous flow. By fitting the experimental data to the numerical solutions of different viscosities, we find that the effective shear viscosity coefficients of shocked aluminum at pressures of 42, 78 and 101 GPa are （1500±100） Pas, （2800±100） Pa.s and （3500±100） Pa.s respectively. It is clear that the shear viscosity of aluminum increases with an increase in shock pressure, so aluminum does not melt below a shock pressure of 101 GPa. This conclusion is consistent with the sound velocity measurement.展开更多
Many of our previous studies have discussed the shock response of symmetrical grain boundaries in iron bicrystals.In this paper, the molecular dynamics simulation of an iron bicrystal containing Σ3 [110] asymmetry ti...Many of our previous studies have discussed the shock response of symmetrical grain boundaries in iron bicrystals.In this paper, the molecular dynamics simulation of an iron bicrystal containing Σ3 [110] asymmetry tilt grain boundary(ATGB) under shock-loading is performed. We find that the shock response of asymmetric grain boundaries is quite different from that of symmetric grain boundaries. Especially, our simulation proves that shock can induce migration of asymmetric grain boundary in iron. We also find that the shape and local structure of grain boundary(GB) would not be changed during shock-induced migration of Σ3 [110] ATGB, while the phase transformation near the GB could affect migration of GB. The most important discovery is that the shock-induced shear stress difference between two sides of GB is the key factor leading to GB migration. Our simulation involves a variety of piston velocities, and the migration of GB seems to be less sensitive to the piston velocity. Finally, the kinetics of GB migration at lattice level is discussed. Our work firstly reports the simulation of shock-induced grain boundary migration in iron. It is of great significance to the theory of GB migration and material engineering.展开更多
Laser shock-processing (LSP) is of particular advantage for improving fa-tigue behavior of small holes and blind holes. Because there are not good accessibility andpassage, these holes cannot be treated by shot peenin...Laser shock-processing (LSP) is of particular advantage for improving fa-tigue behavior of small holes and blind holes. Because there are not good accessibility andpassage, these holes cannot be treated by shot peening or cold extrusion. The fatigue livesof aircraft aluminum alloy 2024-T62 are increased greatly by means of optimization oflaser shocking parameters. With 95 % confidence, the mean fatigue life of LSP specimensis 4. 35~7, 75 times larger than that of the un-shocked ones.展开更多
An essentially conservative adaptive space time conservation element and solution element （CE/SE） method is pro- posed for the effective simulation of shock-induced instability with low computational cost. Its imple...An essentially conservative adaptive space time conservation element and solution element （CE/SE） method is pro- posed for the effective simulation of shock-induced instability with low computational cost. Its implementation is based on redefined conservation elements （CEs） and solution elements （SEs）, optimized interpolations and a Courant number insensitive CE/SE scheme. This approach is used in two applications, the Woodward double Mach reflection and a two- component Richtmyer-Meshkov instability experiment. This scheme reveals the essential features of the investigated cases, captures small unstable structures, and yields a solution that is consistent with the results from experiments or other high order methods.展开更多
The tetracycline （Tet）-off gene expression regulation system based on the TetR-VP16/Top10 construct has not been widely utilized in plants, for its highly expressed TetR-VP16 activator is toxic to some plants and re...The tetracycline （Tet）-off gene expression regulation system based on the TetR-VP16/Top10 construct has not been widely utilized in plants, for its highly expressed TetR-VP16 activator is toxic to some plants and repeatedly replenishing tetracycline to turn off the constitutively active system is a tedious process. To solve these problems, a Tet-off and heat shock （HS）-on gene expression regulation system was constructed in this study. This system is composed of a chimeric transactivator gene TetR-HSF that is derived from a Tet repressor （TetR） and a HS transcription factor （HSF） controlled by a HS promoter HSP70m, and a Tet operator containing hybrid promoter, Om35S, that drives expression of the β-glucuronidase （GUS） gene. The resultant system yields a GUS expression pattern similar to that of the HSP70m promoter under inducing temperatures and at 35 and 40℃ drives GUS expression to a similar level as the Cauliflower mosaic virus （CaMV） 35S promoter. Further examination revealed that the TetR-HSF and GUS genes were induced by HS, reaching peak expression after 1 and 6 h treatment, respectively, and the HS induction of the expression system could be inhibited by Tet. This system will provide a useful tool for transgenic studies of plants in the laboratory and in the field, including transgene function analysis, agronomic trait improvement, biopharmaceutical protein production and others.展开更多
A new shock-capturing method is proposed which is based on upwind schemes and flux-vector splittings. Firstly, original upwind schemes are projected along characteristic directions. Secondly, the amplitudes of the cha...A new shock-capturing method is proposed which is based on upwind schemes and flux-vector splittings. Firstly, original upwind schemes are projected along characteristic directions. Secondly, the amplitudes of the characteristic decompositions are carefully controlled by limiters to prevent non-physical oscillations. Lastly, the schemes are converted into conservative forms, and the oscillation-free shock-capturing schemes are acquired. Two explicit upwind schemes （2nd-order and 3rd-order） and three compact upwind schemes （3rd-order, 5th-order and 7th-order） are modified by the method for hyperbolic systems and the modified schemes are checked on several one-dimensional and two-dimensional test cases. Some numerical solutions of the schemes are compared with those of a WENO scheme and a MP scheme as well as a compact-WENO scheme. The results show that the method with high order accuracy and high resolutions can capture shock waves smoothly.展开更多
In this paper, the quantum hydrodynamics (QHD) model is used to study the propagation of small- but finite-amplitude quantum electrostatic shock-wave in an inertial-less symmetric pair (ion) plasma with immobile backg...In this paper, the quantum hydrodynamics (QHD) model is used to study the propagation of small- but finite-amplitude quantum electrostatic shock-wave in an inertial-less symmetric pair (ion) plasma with immobile background positive constituents. The dispersion due to the quantum tunneling and inertial effects as well as dissipation caused by particle collisions leading to the shock-like or double-layer structures are considered. Investigation of both the stationary and traveling-wave solutions to Kortewege-de Veries-Burgers evolution equation show that critical values exist which govern the type of collective plasma structures. Current analysis apply to diverse kind of symmetric plasmas such as laboratory inertially confined or astrophysical pair-ion or electron-positron degenerate plasmas.展开更多
A systemic and validated model was developed to predict ultraviolet spectra features from the shock layer of near-space hypersonic vehicles in the ＂solar blind＂ band region. Computa- tional procedures were performed...A systemic and validated model was developed to predict ultraviolet spectra features from the shock layer of near-space hypersonic vehicles in the ＂solar blind＂ band region. Computa- tional procedures were performed with 7-species thermal non-equilibrium fluid mechanics, finite rate chemistry, and radiation calculations. The thermal non-equilibrium flow field was calculated with a two-temperature model by the finite volume technique and verified against the bow-shock ultra-violet （BSUV） flight experiments. The absorption coefficient of the mixture gases was evaluated with a line-by-line method and validated through laboratory shock tube measurements. Using the line of sight （LOS） method, radiation was calculated from three BSUV flights at altitudes of 38, 53.5 and 71 km. The investigation focused on the level and structure of ultraviolet spectra radiated from a NO band system in wavelengths of 200-400 nm. Results predicted by the current model show qualitative spatial agreement with the measured data. At a velocity of 3.5 km/s （about Mach 11）, the peak absolute intensity at an altitude of 38 km is two orders of magnitude higher than that at 53.5 km. Under the same flight conditions, the spectra structures have quite a similar distribution at different viewing angles. The present computational model performs well in the prediction of the ultraviolet spectra emitted from the shock layer and will contribute to the investigation and analysis of radiative features of hypersonic vehicles in near space.展开更多
AIM: To compare the effects of extract F of red-rooted Salvia (EFRRS) on mucosal lesions of gastric corpus and antrum induced by hemorrhagic shock and reperfusion in rats. METHODS: The rats were subject to hemorrhagic...AIM: To compare the effects of extract F of red-rooted Salvia (EFRRS) on mucosal lesions of gastric corpus and antrum induced by hemorrhagic shock and reperfusion in rats. METHODS: The rats were subject to hemorrhagic shock and followed by reperfusion, and were divided randomly into two groups. Group 1 received saline, and group 2 received EFRRS intravenously. The index of gastric mucosal lesions (IGML) was expressed as the percentage of lesional area in the corpus or antrum. The degree of gastric mucosal lesions (DGML) was catalogued grade 0,1,2 and 3. The concentrations of prostaglandins (PGs) were measured by radioimmunoassay. The concentration of MDA was measured according to the procedures of Asakawa. The activity of SOD was measured by the biochemical way. The growth rates or inhibitory rates of above-mentioned parameters were calculated. RESULTS: As compared with IGML (%), grade 3 damage (%) and MDA content (nmol/g tissue) of gastric antrum which were respectively 7.96 +/- 0.59, 34.86 +/- 4.96 and 156.98 +/- 16.12, those of gastric corpus which were respectively 23.18 +/- 6.82, 58.44 +/- 9.07 and 230.56 +/- 19.37 increased markedly (P 【0.01), whereas the grade 0 damage, grade 1 damage, the concentrations of PGE(2) and PGI(2)(pg/mg tissue), the ratio of PGI(2)/TXA(2) and the activity of SOD (U/g tissue) of corpus which were respectively 3.01 +/- 1.01, 8.35 +/- 1.95, 540.48 +/- 182.78, 714.38 +/- 123.74, 17.38 +/- 5.93 and 134.29 +/- 13.35 were markedly lower than those of antrum which were respectively 13.92 +/- 2.25, 26.78 +/- 6.06, 2218.56 +/- 433.12, 2531.76 +/- 492.35, 43.46 +/- 8.51 and 187.45 +/- 17.67 (P【0.01) after hemorrhagic shock and reperfusion.After intravenous EFRRS, the growth rates (%) of grade 0 damage, grade 1 damage, the concentrations of PGE(2) and PGI(2), the ratio of PGI(2)/TXA(2) and the activity of SOD of corpus which were respectively 632.56, 308.62, 40.75, 74.75, 92.29 and 122.25 were higher than those in antrum which were respectively 104.89, 58.40, 11.12, 56.58, 30.65 and 82.64, whereas the inhibitory rates (%) of IGML, grade 3 damage and MDA content of gastric corpus were 82.93, 65.32 and 59.09, being higher than those of gastric antrum which were 76.64, 53.18 and 42.37. CONCLUSION: After hemorrhagic shock reperfusion, the gastric mucosal lesions in the corpus were more severe than those in the antrum, which were related not only to the different distribution of endogenous PGs in the mucosa, but also to the different ability of anti-oxidation of the mucosa. The protective effect of EFRRS on the gastric mucosa in the corpus was more evident than that in the antrum, which was related to higher growth degree of PGs contents and anti-oxitative ability in gastric corpus after administration of EFRRS.展开更多
Asymmetric plate impact experiments are conducted on LY12 aluminium alloy in a pressure range of 85-131 GPa. The longitudinal sound speeds axe obtained from the time-resolved particle speed profiles of the specimen me...Asymmetric plate impact experiments are conducted on LY12 aluminium alloy in a pressure range of 85-131 GPa. The longitudinal sound speeds axe obtained from the time-resolved particle speed profiles of the specimen measured with Velocity Interferometer System for Any Reflector （VISAR） technique, and they are shown to be good agreement with our previously reported data of this alloy in a pressure range of 20-70 GPa, and also with those of 2024 aluminium reported by McQueen. Using all of the longitudinal speeds and the corresponding bulk speeds calculated from the Gruneisen equation of state （EOS）, shear moduli of LY12 aluminium alloy are obtained. A comparison of the shear moduli in the solid phase region with those estimated from the Steinberg model demonstrate that the latter are systematically lower than the measurements. By re-analysing the pressure effect on the shear modulus, a modified equation is proposed, in which the pressure term of P/η^1/3 in the Steinberg model is replaced by a linear term. Good agreement between experiments and the modified equation is obtained, which implies that the shear modulus of LY12 aluminium varies linearly both with pressure and with temperature throughout the whole solid phase region. On the other hand, shear modulus of aluminium in a solid-liquid mixed phrase region decreases gradually and smoothly, a feature that is very different from the drastic dropping at the melting point under static conditions.展开更多
Interplanetary shocks or solar wind pressure pulses have prompted impacts on Earth's magnetospheric and ionospheric environment, especially in causing dynamic changes to the bright aurora in the polar ionosphere. ...Interplanetary shocks or solar wind pressure pulses have prompted impacts on Earth's magnetospheric and ionospheric environment, especially in causing dynamic changes to the bright aurora in the polar ionosphere. The auroral phenomenon associated with shock impingements, referred to as shock aurora, exhibits distinct signatures differing from other geophysical features on the dayside polar ionosphere. Shock aurora provides a direct manifestation of the solar wind–magnetosphere–ionosphere interaction. Imagers onboard satellites can obtain the associated large-scale auroral characteristics during shock impingement on the magnetopause. Therefore, auroral data from satellites are very useful for surveying the comprehensive features of shock aurora and their general evolution. Nonetheless, the ground-based high temporal-spatial resolution all-sky imagers installed at scientific stations play an essential role in revealing medium-and small-scale characteristics of shock aurora. Here, we focus on shock aurora imaging signatures measured by imagers onboard satellites and ground-based all-sky imagers.展开更多
The expression of β-D-glucuronidase(Gus)gene under the control of soybean heat shock protein (HSP)promoter Gmhsp17. 5-C was investigated in transgenic Nicotiana plumbaginifolia plants after heat shock treatment. Resu...The expression of β-D-glucuronidase(Gus)gene under the control of soybean heat shock protein (HSP)promoter Gmhsp17. 5-C was investigated in transgenic Nicotiana plumbaginifolia plants after heat shock treatment. Results of histochemical stain assay showed that the Gus activity increased markedly during the recovery phase(21℃)after heat shock treatment at 42℃ for 2 h. Results of quantitative fluorometric assays indicated that maximal Gus activity after heat shock treatment could reach 5-6 times higher than that before heat shock treatment in transgenic lines HG6 and HG9. Based on several advantages of the heat shock promoter such as easy to induce, sensitivity to heat shock and high inductive activity, it can be potentially used to control expression of gene of interest in transgenic plants.展开更多
The Suizhou meteorite is an L6 chondrite. This meteorite is consisted of olivine, low-Ca pyroxene, plagioclase, FeNi metal, troilite, whitlockite, chlorapatite, chromite and ilmenite. Olivine and pyroxene grains displ...The Suizhou meteorite is an L6 chondrite. This meteorite is consisted of olivine, low-Ca pyroxene, plagioclase, FeNi metal, troilite, whitlockite, chlorapatite, chromite and ilmenite. Olivine and pyroxene grains display shock-induced mosaic texture, and most plagioclase grains were melted and transformed to maskelynite. This meteorite contains a few very thin shock-produced melt veins ranging from 20 to 100 μm in width. They are chondritic in composition and contain abundant high-pressure minerals in two assemblages. One is the coarse-grained assemblage of ringwoodite, majorite, lingunite with minor amount of tuite, xieite, the CF-phase, akimotoite and amorphized perovskite, and the fine-grained assemblage (the melt vein matrix) composed of majorite-pyrope garnet, magnesiowüstite. FeNi metal and troilite in the Suizhou shock veins were molten and occur as small intergrowth grains or veinlets filling the interstices of garnet crystals or cracks in the vein matrix. It was revealed that olivine, pyroxene and plagioclase in the Suizhou shock veins have transformed in solid state to their high-pressure polymorphs ringwoodite, majorite, and lingunite, respectively, without change in their chemical compositions.展开更多
The present paper describes a numerical two-way coupling model for shock-induced laminar boundary-layer flows of a dust-laden gas and studies the transverse migration of fine particles under the action of Saffman lift...The present paper describes a numerical two-way coupling model for shock-induced laminar boundary-layer flows of a dust-laden gas and studies the transverse migration of fine particles under the action of Saffman lift force. The governing equations are formulated in the dilute twophase continuum framework with consideration of the finiteness of the particle Reynolds and Knudsen numbers. The full Lagrangian method is explored for calculating the dispersedphase flow fields （including the number density of particles） in the regions of intersecting particle trajectories. The computation results show a significant reaction of the particles on the two-phase boundary-layer structure when the mass loading ratio of particles takes finite values.展开更多
基金supported by the National Natural Science Foundation of China(Nos.11302012,51420105008,51476004,11572025 and 51136003)the National Basic Research Program of China(No.2012CB720205)The computational time for the present study was provided by the UK Turbulence Consortium(EPSRC grant EP/L000261/1)
文摘The efficiency and mechanism of an active control device ＂＇Spark Jet＂ and its application in shock-induced separation control are studied using large-eddy simulation in this paper. The base flow is the interaction of an oblique shock-wave generated by 8° wedge and a spatially-developing Ma = 2.3 turbulent boundary layer. The Reynolds number based on the incoming flow property and the boundary layer displacement thickness at the impinging point without shock-wave is 20000. The detailed numerical approaches were presented. The inflow turbulence was generated using the digital filter method to avoid artificial temporal or streamwise periodicity. The , merical results including velocity profile, Reynolds stress profile, skin friction, and wall pressure were sys- tematically validated against the available wind tunnel particle image velocimetry （PIV） measure- ments of the same flow condition. Further study on the control of flow separation due to the strong shock-viscous interaction using an active control actuator ＂＇Spark Jet＇＂ was conducted. The single-pulsed characteristic of the device was obtained and compared with the experiment. Both instantaneous and time-averaged flow fields have shown that the jet flow issuing from the actuator cavity enhances the flow mixing inside the boundary layer, making the boundary layer more resis- tant to flow separation. Skin friction coefficient distribution shows that the separation bubble length is reduced by about 35% with control exerted.
基金supported by the National Natural Science Foundation of China(Nos.11472188 and11332007)the National Key Research and Development Program of China(No.2016YFA0401200)
文摘Transition prediction is of great importance for the design of long distance flying vehicles. It starts from the problem of receptivity, i.e., how external disturbances trigger instability waves in the boundary layer. For super/hypersonic boundary layers, the external disturbances first interact with the shock ahead of the flying vehicles before entering the boundary layer. Since direct numerical simulation （DNS） is the only available tool for its comprehensive and detailed investigation, an important problem arises whether the numerical scheme, especially the shock-capturing method, can faithfully reproduce the interaction of the external disturbances with the shock, which is so far unknown. This paper is aimed to provide the answer. The interaction of weak disturbances with an oblique shock is investigated, which has a known theoretical solution. Numerical simulation using the shock-capturing method is conducted, and results are compared with those given by theoretical analysis, which shows that the adopted numerical method can faithfully reproduce the interaction of weak external disturbances with the shock.
文摘Stem cell transplantation and low-energy shock-wave therapy （LESWT） have emerged as potential and effective treatment protocols for diabetic erectile dysfunction. During the tracking of transplanted stem cells in diabetic erectile dysfunction models, the number of visible stem cells was rather low and decreased quickly. LESWT could recruit endogenous stem cells to the cavernous body and improve the microenvironment in diabetic cavernous tissue. Thus, we deduced that LESWT might benefit transplanted stem cell survival and improve the effects of stem cell transplantation. In this research, 42 streptozotocin-induced diabetic rats were randomized into four groups： the diabetic group （n = 6）, the LESWT group （n = 6）, the bone marrow-derived mesenchymal stem cell （BMSC） transplantation group （n = 15）, and the combination of LESWT and BMSC transplantation group （n = 15）. One and three days after BMSC transplantation, three rats were randomly chosen to observe the survival numbers of BMSCs in the cavernous body. Four weeks after BMSC transplantation, the following parameters were assessed： the surviving number of transplanted BMSCs in the cavernous tissue, erectile function, real-time polymerase chain reaction, and penile immunohistochemical assessment. Our research found that LESWT favored the survival of transplanted BMSCs in the cavernous body, which might be related to increased stromal cell-derived factor-1 expression and the enhancement of angiogenesis in the diabetic cavernous tissue. The combination of LESWT and BMSC transplantation could improve the erectile function of diabetic erectile function rats more effectively than LESWT or BMSC transplantation performed alone.
基金supported by the National Natural Science Foundation of China (No.11302012,51376001,51136003)the National Basic Research Program of China (No.2012CB720205)+3 种基金the National Magnetic Confinement Fusion Research Program of China (No.2012GB102006)the Aeronautical Science Foundation of China (No.2012ZB51014)the ‘‘111’’ Project(No.B08009)the Astronautical Technology Innovation Foundation of China
文摘It is of great significance to improve the accuracy of turbulence models in shock-wave/ boundary layer interaction flow. The relationship between the pressure gradient, as well as the shear layer, and the development of turbulent kinetic energy in impinging shock-wave/turbulent bound- ary layer interaction flow at Mach 2.25 is analyzed based on the data of direct numerical simulation （DNS）. It is found that the turbulent kinetic energy is amplified by strong shear in the separation zone and the adverse pressure gradient near the separation point. The pressure gradient was non-dimensionalised with local density, velocity, and viscosity. Spalart Allmaras （S A） model is modified by introducing the non-dimensional pressure gradient into the production term of the eddy viscosity transportation equation. Simulation results show that the production and dissipation of eddy viscosity are strongly enhanced by the modification of S-A model. Compared with DNS and experimental data, the wall pressure and the wall skin friction coefficient as well as the velocity profile of the modified S-A model are obviously improved. Thus it can be concluded that the mod- ification of S-A model with the pressure gradient can improve the predictive accuracy for simulat- ing the shock-wave/turbulent boundary laver interaction.
基金supported by the National Natural Science Foundation of China (10972214 and 11172278)the Fundamental Research Funds for the Central Universities (WK2090050014)
文摘The influences of the acoustic impedance and shock strength on the jet formation in shock-heavy gas bubble interaction are numerically studied in this work. The process of a shock interacting with a krypton or a SF6 bubble is studied by the numerical method VAS2D. As a validation, the experiments of a SF6 bubble accelerated by a planar shock were performed. The results indicate that, due to the mismatch of acoustic impedance, the way of jet formation in heavy gas bubble with different species is diversified under the same initial condition. With respect to the same bubble, the manner of jet formation is also distinctly different under different shock strengths. The disparities of the acoustic impedance result in different effects of shock focusing in the bubble, and different behaviors of shock wave inside and outside the bubble. The analyses of the wave pattern and the pressure variation indicate that the jet formation is closely associated with the pressure perturbation. Moreover, the analy- sis of the vorticity deposition, and comparisons of circulation and baroclinic torque show that the baroclinic vorticity also contributes to the jet formation. It is concluded that the pres- sure perturbation and baroclinic vorticity deposition are the two dominant factors for the jet formation in shock-heavy gas bubble interaction.
文摘A comprehensive methodology for simulating 2 D dynamic stall at fluctuating freestream is proposed in this paper.2 D CFD simulation of a SC1095 airfoil exposed to a fluctuating freestream of Mach number 0.537±0.205 and Reynolds number 6.1×10~6(based on the mean Mach number)and undergoing a 10°±10°pitch oscillation with a frequency of 4.25 Hz was conducted.These conditions were selected to be representative of the flow experienced by a helicopter rotor airfoil section in a real-life fast forward flight.Both constant freestream dynamic stall as well as fluctuating freestream dynamic stall simulations were conducted and compared.The methodology was carefully validated with experimental data for both transonic flow and dynamic stall under fluctuating freestream.Overall,the results suggest that the fluctuating freestream alters the dynamic stall mechanism documented for constant freestream in a major way,emphasizing that inclusion of this effect in the prediction of dynamic stall related rotor loads is imperative for rotor performance analysis and blades design.
基金Project supported by the National Natural Science Foundation of China (Grant Nos. 11002120 and 10974160)
文摘A reliable data treatment method is critical for viscosity measurements using the disturbance amplitude damping method of shock waves. In this paper the finite difference method is used to obtain the numerical solutions for the disturbance amplitude damping behaviour of the sinusoidal shock front in a flyer-impact experiment. The disturbance amplitude damping curves are used to depict the numerical solutions of viscous flow. By fitting the experimental data to the numerical solutions of different viscosities, we find that the effective shear viscosity coefficients of shocked aluminum at pressures of 42, 78 and 101 GPa are （1500±100） Pas, （2800±100） Pa.s and （3500±100） Pa.s respectively. It is clear that the shear viscosity of aluminum increases with an increase in shock pressure, so aluminum does not melt below a shock pressure of 101 GPa. This conclusion is consistent with the sound velocity measurement.
基金Project supported by the Fundamental Research for the Central Universities of Chinathe National Key Laboratory Project of Shock Wave and Detonation Physics of China+4 种基金the Science and Technology Foundation of National Key Laboratory of Shock Wave and Detonation Physics of Chinathe National Key R&D Program of China(Grant No.2017YFB0202303)the National Natural Science Foundation of China(Grant Nos.51871094,51871095,51571088,NSFC-NSAF U1530151,and U1830138)the Natural Science Foundation of Hunan Province of China(Grant No.2018JJ2036)the Science Challenge Project of China(Grant No.TZ2016001)
文摘Many of our previous studies have discussed the shock response of symmetrical grain boundaries in iron bicrystals.In this paper, the molecular dynamics simulation of an iron bicrystal containing Σ3 [110] asymmetry tilt grain boundary(ATGB) under shock-loading is performed. We find that the shock response of asymmetric grain boundaries is quite different from that of symmetric grain boundaries. Especially, our simulation proves that shock can induce migration of asymmetric grain boundary in iron. We also find that the shape and local structure of grain boundary(GB) would not be changed during shock-induced migration of Σ3 [110] ATGB, while the phase transformation near the GB could affect migration of GB. The most important discovery is that the shock-induced shear stress difference between two sides of GB is the key factor leading to GB migration. Our simulation involves a variety of piston velocities, and the migration of GB seems to be less sensitive to the piston velocity. Finally, the kinetics of GB migration at lattice level is discussed. Our work firstly reports the simulation of shock-induced grain boundary migration in iron. It is of great significance to the theory of GB migration and material engineering.
文摘Laser shock-processing (LSP) is of particular advantage for improving fa-tigue behavior of small holes and blind holes. Because there are not good accessibility andpassage, these holes cannot be treated by shot peening or cold extrusion. The fatigue livesof aircraft aluminum alloy 2024-T62 are increased greatly by means of optimization oflaser shocking parameters. With 95 % confidence, the mean fatigue life of LSP specimensis 4. 35~7, 75 times larger than that of the un-shocked ones.
基金Project supported by the National Natural Science Foundation of China (Grant Nos.10732010,10972010,and 11028206)the Opening Project of State Key Laboratory of Explosion Science and Technology,China (Grant No.KFJJ13-5M)
文摘An essentially conservative adaptive space time conservation element and solution element （CE/SE） method is pro- posed for the effective simulation of shock-induced instability with low computational cost. Its implementation is based on redefined conservation elements （CEs） and solution elements （SEs）, optimized interpolations and a Courant number insensitive CE/SE scheme. This approach is used in two applications, the Woodward double Mach reflection and a two- component Richtmyer-Meshkov instability experiment. This scheme reveals the essential features of the investigated cases, captures small unstable structures, and yields a solution that is consistent with the results from experiments or other high order methods.
基金supported by the National High-Tech R&D Program of China(2010AA10060705)the Transgenic Engineering Crops Breeding Special Funds from China’s Ministry of Agriculture(2009ZX08010-005B)
文摘The tetracycline （Tet）-off gene expression regulation system based on the TetR-VP16/Top10 construct has not been widely utilized in plants, for its highly expressed TetR-VP16 activator is toxic to some plants and repeatedly replenishing tetracycline to turn off the constitutively active system is a tedious process. To solve these problems, a Tet-off and heat shock （HS）-on gene expression regulation system was constructed in this study. This system is composed of a chimeric transactivator gene TetR-HSF that is derived from a Tet repressor （TetR） and a HS transcription factor （HSF） controlled by a HS promoter HSP70m, and a Tet operator containing hybrid promoter, Om35S, that drives expression of the β-glucuronidase （GUS） gene. The resultant system yields a GUS expression pattern similar to that of the HSP70m promoter under inducing temperatures and at 35 and 40℃ drives GUS expression to a similar level as the Cauliflower mosaic virus （CaMV） 35S promoter. Further examination revealed that the TetR-HSF and GUS genes were induced by HS, reaching peak expression after 1 and 6 h treatment, respectively, and the HS induction of the expression system could be inhibited by Tet. This system will provide a useful tool for transgenic studies of plants in the laboratory and in the field, including transgene function analysis, agronomic trait improvement, biopharmaceutical protein production and others.
基金Project supported by the National Natural Science Foundation of China (Nos.10321002 and 10672012)
文摘A new shock-capturing method is proposed which is based on upwind schemes and flux-vector splittings. Firstly, original upwind schemes are projected along characteristic directions. Secondly, the amplitudes of the characteristic decompositions are carefully controlled by limiters to prevent non-physical oscillations. Lastly, the schemes are converted into conservative forms, and the oscillation-free shock-capturing schemes are acquired. Two explicit upwind schemes （2nd-order and 3rd-order） and three compact upwind schemes （3rd-order, 5th-order and 7th-order） are modified by the method for hyperbolic systems and the modified schemes are checked on several one-dimensional and two-dimensional test cases. Some numerical solutions of the schemes are compared with those of a WENO scheme and a MP scheme as well as a compact-WENO scheme. The results show that the method with high order accuracy and high resolutions can capture shock waves smoothly.
文摘In this paper, the quantum hydrodynamics (QHD) model is used to study the propagation of small- but finite-amplitude quantum electrostatic shock-wave in an inertial-less symmetric pair (ion) plasma with immobile background positive constituents. The dispersion due to the quantum tunneling and inertial effects as well as dissipation caused by particle collisions leading to the shock-like or double-layer structures are considered. Investigation of both the stationary and traveling-wave solutions to Kortewege-de Veries-Burgers evolution equation show that critical values exist which govern the type of collective plasma structures. Current analysis apply to diverse kind of symmetric plasmas such as laboratory inertially confined or astrophysical pair-ion or electron-positron degenerate plasmas.
基金supported by the National Natural Science Foundation of China (No.51176039)
文摘A systemic and validated model was developed to predict ultraviolet spectra features from the shock layer of near-space hypersonic vehicles in the ＂solar blind＂ band region. Computa- tional procedures were performed with 7-species thermal non-equilibrium fluid mechanics, finite rate chemistry, and radiation calculations. The thermal non-equilibrium flow field was calculated with a two-temperature model by the finite volume technique and verified against the bow-shock ultra-violet （BSUV） flight experiments. The absorption coefficient of the mixture gases was evaluated with a line-by-line method and validated through laboratory shock tube measurements. Using the line of sight （LOS） method, radiation was calculated from three BSUV flights at altitudes of 38, 53.5 and 71 km. The investigation focused on the level and structure of ultraviolet spectra radiated from a NO band system in wavelengths of 200-400 nm. Results predicted by the current model show qualitative spatial agreement with the measured data. At a velocity of 3.5 km/s （about Mach 11）, the peak absolute intensity at an altitude of 38 km is two orders of magnitude higher than that at 53.5 km. Under the same flight conditions, the spectra structures have quite a similar distribution at different viewing angles. The present computational model performs well in the prediction of the ultraviolet spectra emitted from the shock layer and will contribute to the investigation and analysis of radiative features of hypersonic vehicles in near space.
基金Supported by the National Natural Science Foundation of China.No.3870890
文摘AIM: To compare the effects of extract F of red-rooted Salvia (EFRRS) on mucosal lesions of gastric corpus and antrum induced by hemorrhagic shock and reperfusion in rats. METHODS: The rats were subject to hemorrhagic shock and followed by reperfusion, and were divided randomly into two groups. Group 1 received saline, and group 2 received EFRRS intravenously. The index of gastric mucosal lesions (IGML) was expressed as the percentage of lesional area in the corpus or antrum. The degree of gastric mucosal lesions (DGML) was catalogued grade 0,1,2 and 3. The concentrations of prostaglandins (PGs) were measured by radioimmunoassay. The concentration of MDA was measured according to the procedures of Asakawa. The activity of SOD was measured by the biochemical way. The growth rates or inhibitory rates of above-mentioned parameters were calculated. RESULTS: As compared with IGML (%), grade 3 damage (%) and MDA content (nmol/g tissue) of gastric antrum which were respectively 7.96 +/- 0.59, 34.86 +/- 4.96 and 156.98 +/- 16.12, those of gastric corpus which were respectively 23.18 +/- 6.82, 58.44 +/- 9.07 and 230.56 +/- 19.37 increased markedly (P 【0.01), whereas the grade 0 damage, grade 1 damage, the concentrations of PGE(2) and PGI(2)(pg/mg tissue), the ratio of PGI(2)/TXA(2) and the activity of SOD (U/g tissue) of corpus which were respectively 3.01 +/- 1.01, 8.35 +/- 1.95, 540.48 +/- 182.78, 714.38 +/- 123.74, 17.38 +/- 5.93 and 134.29 +/- 13.35 were markedly lower than those of antrum which were respectively 13.92 +/- 2.25, 26.78 +/- 6.06, 2218.56 +/- 433.12, 2531.76 +/- 492.35, 43.46 +/- 8.51 and 187.45 +/- 17.67 (P【0.01) after hemorrhagic shock and reperfusion.After intravenous EFRRS, the growth rates (%) of grade 0 damage, grade 1 damage, the concentrations of PGE(2) and PGI(2), the ratio of PGI(2)/TXA(2) and the activity of SOD of corpus which were respectively 632.56, 308.62, 40.75, 74.75, 92.29 and 122.25 were higher than those in antrum which were respectively 104.89, 58.40, 11.12, 56.58, 30.65 and 82.64, whereas the inhibitory rates (%) of IGML, grade 3 damage and MDA content of gastric corpus were 82.93, 65.32 and 59.09, being higher than those of gastric antrum which were 76.64, 53.18 and 42.37. CONCLUSION: After hemorrhagic shock reperfusion, the gastric mucosal lesions in the corpus were more severe than those in the antrum, which were related not only to the different distribution of endogenous PGs in the mucosa, but also to the different ability of anti-oxidation of the mucosa. The protective effect of EFRRS on the gastric mucosa in the corpus was more evident than that in the antrum, which was related to higher growth degree of PGs contents and anti-oxitative ability in gastric corpus after administration of EFRRS.
基金Project supported by the National Natural Science Foundation of China (Grant Nos 10232040 and 10672149)the foundation of Laboratory for Shock Wave and Detonation Physics Research, China Academy of Engineering Physics (Grant No 9140C6702020603)
文摘Asymmetric plate impact experiments are conducted on LY12 aluminium alloy in a pressure range of 85-131 GPa. The longitudinal sound speeds axe obtained from the time-resolved particle speed profiles of the specimen measured with Velocity Interferometer System for Any Reflector （VISAR） technique, and they are shown to be good agreement with our previously reported data of this alloy in a pressure range of 20-70 GPa, and also with those of 2024 aluminium reported by McQueen. Using all of the longitudinal speeds and the corresponding bulk speeds calculated from the Gruneisen equation of state （EOS）, shear moduli of LY12 aluminium alloy are obtained. A comparison of the shear moduli in the solid phase region with those estimated from the Steinberg model demonstrate that the latter are systematically lower than the measurements. By re-analysing the pressure effect on the shear modulus, a modified equation is proposed, in which the pressure term of P/η^1/3 in the Steinberg model is replaced by a linear term. Good agreement between experiments and the modified equation is obtained, which implies that the shear modulus of LY12 aluminium varies linearly both with pressure and with temperature throughout the whole solid phase region. On the other hand, shear modulus of aluminium in a solid-liquid mixed phrase region decreases gradually and smoothly, a feature that is very different from the drastic dropping at the melting point under static conditions.
基金supported by the NSFC (Grant nos. 41431072, 41674169, 41474146, and 41831072)the International Collaboration Supporting Project by the Chinese Arctic and Antarctic Administration (Grant no. IC201608)+1 种基金the National Key R&D Program of China (Grant no. 2018YFC1407304)the Chinese Meridian Project
文摘Interplanetary shocks or solar wind pressure pulses have prompted impacts on Earth's magnetospheric and ionospheric environment, especially in causing dynamic changes to the bright aurora in the polar ionosphere. The auroral phenomenon associated with shock impingements, referred to as shock aurora, exhibits distinct signatures differing from other geophysical features on the dayside polar ionosphere. Shock aurora provides a direct manifestation of the solar wind–magnetosphere–ionosphere interaction. Imagers onboard satellites can obtain the associated large-scale auroral characteristics during shock impingement on the magnetopause. Therefore, auroral data from satellites are very useful for surveying the comprehensive features of shock aurora and their general evolution. Nonetheless, the ground-based high temporal-spatial resolution all-sky imagers installed at scientific stations play an essential role in revealing medium-and small-scale characteristics of shock aurora. Here, we focus on shock aurora imaging signatures measured by imagers onboard satellites and ground-based all-sky imagers.
基金supported by the National High Tech R&D Program of China(863 Program,2002AA2244011)the National Special Program for Research and Industrialization of Ttansgenic Plants,China(J2000-B-021).
文摘The expression of β-D-glucuronidase(Gus)gene under the control of soybean heat shock protein (HSP)promoter Gmhsp17. 5-C was investigated in transgenic Nicotiana plumbaginifolia plants after heat shock treatment. Results of histochemical stain assay showed that the Gus activity increased markedly during the recovery phase(21℃)after heat shock treatment at 42℃ for 2 h. Results of quantitative fluorometric assays indicated that maximal Gus activity after heat shock treatment could reach 5-6 times higher than that before heat shock treatment in transgenic lines HG6 and HG9. Based on several advantages of the heat shock promoter such as easy to induce, sensitivity to heat shock and high inductive activity, it can be potentially used to control expression of gene of interest in transgenic plants.
文摘The Suizhou meteorite is an L6 chondrite. This meteorite is consisted of olivine, low-Ca pyroxene, plagioclase, FeNi metal, troilite, whitlockite, chlorapatite, chromite and ilmenite. Olivine and pyroxene grains display shock-induced mosaic texture, and most plagioclase grains were melted and transformed to maskelynite. This meteorite contains a few very thin shock-produced melt veins ranging from 20 to 100 μm in width. They are chondritic in composition and contain abundant high-pressure minerals in two assemblages. One is the coarse-grained assemblage of ringwoodite, majorite, lingunite with minor amount of tuite, xieite, the CF-phase, akimotoite and amorphized perovskite, and the fine-grained assemblage (the melt vein matrix) composed of majorite-pyrope garnet, magnesiowüstite. FeNi metal and troilite in the Suizhou shock veins were molten and occur as small intergrowth grains or veinlets filling the interstices of garnet crystals or cracks in the vein matrix. It was revealed that olivine, pyroxene and plagioclase in the Suizhou shock veins have transformed in solid state to their high-pressure polymorphs ringwoodite, majorite, and lingunite, respectively, without change in their chemical compositions.
基金The project supported by the National Natural Science Foundation of China(90205024)Russian Foundation for Basic Research(RFBR and(RFBR-NSFC-39004)
文摘The present paper describes a numerical two-way coupling model for shock-induced laminar boundary-layer flows of a dust-laden gas and studies the transverse migration of fine particles under the action of Saffman lift force. The governing equations are formulated in the dilute twophase continuum framework with consideration of the finiteness of the particle Reynolds and Knudsen numbers. The full Lagrangian method is explored for calculating the dispersedphase flow fields （including the number density of particles） in the regions of intersecting particle trajectories. The computation results show a significant reaction of the particles on the two-phase boundary-layer structure when the mass loading ratio of particles takes finite values.
