期刊文献+
共找到265篇文章
< 1 2 14 >
每页显示 20 50 100
Dynamic Characteristics Analysis of Ice-Adhesion Transmission Tower-Line System under Effect of Wind-Induced Ice Shedding 被引量:4
1
作者 Yongping Yu Lihui Chen +1 位作者 JuanjuanWang Guoji Liu 《Computer Modeling in Engineering & Sciences》 SCIE EI 2020年第11期647-670,共24页
The tower line system will be in an unsafe status due to uniform or uneven fall of ice coating which is attached to the surface of tower and lines.The fall of ice could be caused by wind action or thermal force.In ord... The tower line system will be in an unsafe status due to uniform or uneven fall of ice coating which is attached to the surface of tower and lines.The fall of ice could be caused by wind action or thermal force.In order to study the dynamic characteristics of the self-failure of the transmission line under the action of dynamicwind load,a finite elementmodel of the two-span transmission tower line system was established.The birth and death element methods are used to simulate the icing and shedding of the line.Tensile failure strength is the shedding criterion for ice coating.The fluctuating wind speed time history of the tower line systemis first simulated,and then the fluctuating wind and the average wind are superimposed to generate the instantaneous wind speed and converted into wind load.The dynamic response of the transmission tower line systemunder iced coupling with different wind speeds and different thicknesses of ice coating was studied.This is the first attempt that the coupling dynamic response of the icing shedding and wind load for the transmission tower-line system is discussed in this paper.In addition,the dynamic characteristics of wind are included.In particular,the limiting mechanical conditions are considered.According to the simulation results,it is found:because of the ice shedding,the stress of the conductor changes obviously in the first 20 seconds,and the ground wire changes sharply in the first two seconds;the icing of the conductor(ground)wire is gradually deicing under the action of wind vibration;the displacement of tower top increases with the increase of wind speed and icing thickness. 展开更多
关键词 Tower line system fluctuating wind ice shedding dynamic response wind-induced ice shedding
在线阅读 下载PDF
Optimal integration of solar home systems and appliance scheduling for residential homes under severe national load shedding
2
作者 Sakhile Twala Xianming Ye +1 位作者 Xiaohua Xia Lijun Zhang 《Journal of Automation and Intelligence》 2023年第4期227-238,共12页
In developing countries like South Africa,users experienced more than 1030 hours of load shedding outages in just the first half of 2023 due to inadequate power supply from the national grid.Residential homes that can... In developing countries like South Africa,users experienced more than 1030 hours of load shedding outages in just the first half of 2023 due to inadequate power supply from the national grid.Residential homes that cannot afford to take actions to mitigate the challenges of load shedding are severely inconvenienced as they have to reschedule their demand involuntarily.This study presents optimal strategies to guide households in determining suitable scheduling and sizing solutions for solar home systems to mitigate the inconvenience experienced by residents due to load shedding.To start with,we predict the load shedding stages that are used as input for the optimal strategies by using the K-Nearest Neighbour(KNN)algorithm.Based on an accurate forecast of the future load shedding patterns,we formulate the residents’inconvenience and the loss of power supply probability during load shedding as the objective function.When solving the multi-objective optimisation problem,four different strategies to fight against load shedding are identified,namely(1)optimal home appliance scheduling(HAS)under load shedding;(2)optimal HAS supported by solar panels;(3)optimal HAS supported by batteries,and(4)optimal HAS supported by the solar home system with both solar panels and batteries.Among these strategies,appliance scheduling with an optimally sized 9.6 kWh battery and a 2.74 kWp panel array of five 550 Wp panels,eliminates the loss of power supply probability and reduces the inconvenience by 92%when tested under the South African load shedding cases in 2023. 展开更多
关键词 Load shedding Inconvenience Optimal scheduling and sizing strategies K-Nearest Neighbour(KNN) Multi-objective mixed integer nonlinear optimisation
在线阅读 下载PDF
Optimum Load Shedding in Power System Strategies with Voltage Stability Indicators
3
作者 P.V. RAJ M. SUDHAKARAN 《Engineering(科研)》 2010年第1期12-21,共10页
An optimal load shedding strategy for power systems with optimum location and quantity of load to be shed is presented in this paper. The problem of load shedding for avoiding the existence of voltage instability in p... An optimal load shedding strategy for power systems with optimum location and quantity of load to be shed is presented in this paper. The problem of load shedding for avoiding the existence of voltage instability in power systems is taken as a remedial action during emergency state in transmission and distribution sector.Optimum location of loads to be shed is found together with their optimum required quantity. L-Indicator index is in used for this purpose with a modified new technique. Applications to be standard 6 bus Ward-Hale test system and IEEE – 14 bus system are presented to validate the applicability of the proposed technique to any system of any size. 展开更多
关键词 Load shedding Voltage INSTABILITY POWER systems Transmission and Distribution POWER system
在线阅读 下载PDF
Identification of Critical Lines in Power System Based on Optimal Load Shedding
4
作者 Mingshun Liu Lijin Zhao +3 位作者 Liang Huang Xiaowei Zhang Changhong Deng Zhijun Long 《Energy and Power Engineering》 2017年第4期261-269,共9页
Based on risk theory, considering the probability of an accident and the severity of the sequence, combining N-1 and N-2 security check, this paper puts forward a new risk index, which uses the amount of optimal load ... Based on risk theory, considering the probability of an accident and the severity of the sequence, combining N-1 and N-2 security check, this paper puts forward a new risk index, which uses the amount of optimal load shedding as the severity of an accident consequence to identify the critical lines in power system. Taking IEEE24-RTS as an example, the simulation results verify the correctness and effectiveness of the proposed index. 展开更多
关键词 Risk Theory Optimal Power Flow Load shedding Risk Index Critical Line Identification
在线阅读 下载PDF
Niupai Machinery&Elecronics:Bring a variety of shedding devices and heald frame equipment to the exhibition
5
《China Textile》 2025年第5期50-50,共1页
Jiangsu Niupai Machinery&Elecronics Co,ltd.is National Specialized and New"Little Giant"Enterprise,National High&New Technological Enterprise,Jiangsu Provincial Research Center of Loom Shedding Engin... Jiangsu Niupai Machinery&Elecronics Co,ltd.is National Specialized and New"Little Giant"Enterprise,National High&New Technological Enterprise,Jiangsu Provincial Research Center of Loom Shedding Engineering Technology and Jiangsu Provincial Enterprise Technology Center.The company has obtained SGS-certified ISO9001 quality management system,a globally recognized standard.Niupai specializes in the R&D and manufacturing of cam shedding device,dobby shedding device,jacquard shedding device and heald frames for water-jet looms,air-jet looms as well as rapier looms. 展开更多
关键词 national specialized newlittle giant enterprise quality management loom shedding engineering technology cam shedding devicedobby shedding devicejacquard shedding device loom shedding engineering heald frame equipment national high new technological enterprise heald frames
在线阅读 下载PDF
Changshu Textile Machinery:Focusing on the shedding devices R&D for more than 60 years
6
《China Textile》 2025年第5期47-47,共1页
Changshu Textile Machinery Works Co.,Ltd.was founded in 1958 and is a professional R&D and manufacturing enterprise of looms shedding device in China.The company's products cover three series of shedding devic... Changshu Textile Machinery Works Co.,Ltd.was founded in 1958 and is a professional R&D and manufacturing enterprise of looms shedding device in China.The company's products cover three series of shedding devices for looms(Dobby,Jacquard,Cam Motion),forming a series of products with electronic shedding devices as the main products,and mechanical shedding devices as the auxiliary products.D2876pro electronic dobby The D2876pro electronic dobby is a high-performance equipment designed for a maximum operating speed of 800rpm.It has 16 cams,and 12mm of pitch,with a high installation type.The shedding type is double lift and full clear open.Its maximum wefts is 12,800 and 100,000.It has a two-stage filtration lubrication with a gerotor pump oil recycle system,and it is suitable for water-jet looms. 展开更多
关键词 dobby loom d pro electronic dobby high performance equipment electronic shedding devices shedding device electronic dobby shedding devices
在线阅读 下载PDF
Interference mechanism of trailing edge flap shedding vortices with rotor wake and aerodynamic characteristics
7
作者 Yang LIU Yongjie SHI +2 位作者 Aqib AZIZ Guohua XU Haifeng GAO 《Chinese Journal of Aeronautics》 2025年第1期325-339,共15页
A robust Reynolds-Averaged Navier-Stokes(RANS)based solver is established to predict the complex unsteady aerodynamic characteristics of the Active Flap Control(AFC)rotor.The complex motion with multiple degrees of fr... A robust Reynolds-Averaged Navier-Stokes(RANS)based solver is established to predict the complex unsteady aerodynamic characteristics of the Active Flap Control(AFC)rotor.The complex motion with multiple degrees of freedom of the Trailing Edge Flap(TEF)is analyzed by employing an inverse nested overset grid method.Simulation of non-rotational and rotational modes of blade motion are carried out to investigate the formation and development of TEF shedding vortex with high-frequency deflection of TEF.Moreover,the mechanism of TEF deflection interference with blade tip vortex and overall rotor aerodynamics is also explored.In nonrotational mode,two bundles of vortices form at the gap ends of TEF and the main blade and merge into a single TEF vortex.Dynamic deflection of the TEF significantly interferes with the blade tip vortex.The position of the blade tip vortex consistently changes,and its frequency is directly related to the frequency of TEF deflection.In rotational mode,the tip vortex forms a helical structure.The end vortices at the gap sides co-swirl and subsequently merge into the concentrated beam of tip vortices,causing fluctuations in the vorticity and axial position of the tip vortex under the rotor.This research concludes with the investigation on suppression of Blade Vortex Interaction(BVI),showing an increase in miss distance and reduction in the vorticity of tip vortex through TEF phase control at a particular control frequency.Through this mechanism,a designed TEF deflection law increases the miss distance by 34.7%and reduces vorticity by 11.9%at the target position,demonstrating the effectiveness of AFC in mitigating BVI. 展开更多
关键词 CFD ROTOR Aerodynamic Trailing edge flap Vortex shedding BVI
原文传递
An Electro⁃thermal De⁃icing Model and Simulation Analysis Considering Ice Shedding
8
作者 ZHANG Yingying YUAN Xiansheng +1 位作者 XIONG Jingjiang BU Xueqin 《Transactions of Nanjing University of Aeronautics and Astronautics》 2025年第2期162-177,共16页
The electro⁃thermal anti/de-icing systems have high heating efficiency and relatively simple structures,marking them as a key development direction for future icing protection.Existing simulation algorithms for electr... The electro⁃thermal anti/de-icing systems have high heating efficiency and relatively simple structures,marking them as a key development direction for future icing protection.Existing simulation algorithms for electrothermal de-icing seldom delve into comprehensive ice accretion-melting-deicing models that account for ice shedding.Therefore,the detachment behavior of ice layers during the heating process requires in-depth research and discussion.This paper physically models the phenomenon of ice shedding,incorporates the detachment behavior of ice layers during heating,improves the existing mathematical model for electro-thermal de-icing calculations,establishes an ice accretion-melting-deicing model for electro-thermal de-icing systems,and conducts numerical simulation,verification and optimization analysis of electro-thermal de-icing considering ice shedding.Through multi-condition de-icing numerical simulations of a specific wing model,it is found that ambient temperature can serve as a factor for adapting the electro heating anti/de-icing strategy to the environment.An optimization of heating heat flux density and heating/cooling time is conducted for the wing de-icing control law under the calculated conditions.The improved electrothermal de-icing model and algorithm developed in this paper provide solid technical support for the design of electrothermal de-icing systems. 展开更多
关键词 aircraft icing electro-thermal de-icing ice shedding electro-thermal control law numerical simulation
在线阅读 下载PDF
Research Progress on High-Energy Rechargeable Sn-Based Batteries
9
作者 Yao Dong Rongli Wang Yingjian Yu 《Carbon Energy》 2026年第1期153-175,共23页
Sn-based batteries have emerged as an optimal energy storage system owing to their abundant Sn resources,environmental compatibility,non-toxicity,corrosion resistance,and high hydrogen evolution overpotential.However,... Sn-based batteries have emerged as an optimal energy storage system owing to their abundant Sn resources,environmental compatibility,non-toxicity,corrosion resistance,and high hydrogen evolution overpotential.However,the practical application of these batteries is hindered by challenges such as“dead Sn”shedding and hydrogen evolution side reactions.Extensive research has focused on improving the performance of Sn-based batteries.This paper provides a comprehensive review of the recent advancements in Sn-based battery research,including the selection of current collectors,electrolyte optimization,and the development of new cathode materials.The energy storage mechanisms and challenges of Sn-based batteries are discussed.Overall,this paper presents future perspectives of high-performance rechargeable Sn-based batteries and provides valuable guidance for developing Sn-based energy storage technologies. 展开更多
关键词 cathode materials current collectors dead Sn shedding electrolytes Sn-based batteries
在线阅读 下载PDF
The transmembrane domain of TACE regulates protein ectodomain shedding 被引量:6
10
作者 Xiaojin Li Liliana Pére +1 位作者 Zui Pan Huizhou Fan 《Cell Research》 SCIE CAS CSCD 2007年第12期985-998,共14页
Numerous membrane proteins are cleaved by tumor necrosis factor-α converting enzyme (TACE), which causes the release of their ectodomains. An ADAM (a disintegrin and metalloprotease domain) family member, TACE co... Numerous membrane proteins are cleaved by tumor necrosis factor-α converting enzyme (TACE), which causes the release of their ectodomains. An ADAM (a disintegrin and metalloprotease domain) family member, TACE contains several noncatalytic domains whose roles in ectodomain shedding have yet to be fully resolved. Here, we have explored the function of the transmembrane domain (TM) of TACE by coupling molecular engineering and functional analysis. A TM-free TACE construct that is anchored to the plasma membrane by a glycosylphosphatidylinositol (GPI)-binding polypeptide failed to restore shedding of transforming growth factor-or (TGF-α), tumor necrosis factor-α (TNF-α) and L-selectin in cells lacking endogenous TACE activity. Substitution of the TACE TM with that of the prolactin receptor or platelet-derived growth factor receptor (PDGFR) also resulted in severe loss of TGF-α shedding, but had no effects on the cleavage of TNF-α and L-selectin. Replacement of the TM in TGF-α with that of L-selectin enabled TGF-α shedding by the TACE mutants carrying the TM of prolactin receptor and PDGFR. Taken together, our observations suggest that anchorage of TACE to the lipid bilayer through a TM is required for efficient cleavage of a broad spectrum of substrates, and that the amino-acid sequence of TACE TM may play a role in regulatory specificity among TACE substrates. 展开更多
关键词 transmembrane domain TACE/ADAM17 ectodomain shedding transforming growth factor-α tumor necrosis factor-α L-SELECTIN
暂未订购
Influence of thermal inhibitor position and temperature on vortex-shedding-driven pressure oscillations 被引量:6
11
作者 Su Wanxing Li Shipeng +3 位作者 Zhang Qiao Li Junwei Ye Qingqing Wang Ningfei 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2013年第3期544-553,共10页
Vortex-acoustic coupling is one of the most important potential sources of combustion instability in solid rocket motors (SRMs). Based on the Von Karman Institute for Fluid Dynamics (VKI) experimental motor, the i... Vortex-acoustic coupling is one of the most important potential sources of combustion instability in solid rocket motors (SRMs). Based on the Von Karman Institute for Fluid Dynamics (VKI) experimental motor, the influence of the thermal inhibitor position and temperature on vortex-shedding-driven pressure oscillations is numerically studied via the large eddy simulation (LES) method. The simulation results demonstrate that vortex shedding is a periodic process and its accurate frequency can be numerically obtained. Acoustic modes could be easily excited by vortex shedding. The vortex shedding frequency and second acoustic frequency dominate the pressure oscillation characteristics in the chamber. Thermal inhibitor position and gas temperature have little effect on vortex shedding frequency, but have great impact on pressure oscillation amplitude. Pressure amplitude is much higher when the thermal inhibitor locates at the acoustic velocity anti-nodes. The farther the thermal inhibitor is to the nozzle head, the more vortex energy would be dissipated by the turbulence. Therefore, the vortex shedding amplitude at the second acoustic velocity antinode near 3/4L (L is chamber length) is larger than those of others. Besides, the natural acoustic frequencies increase with the gas temperature. As the vortex shedding frequency departs from the natural acoustic frequency, the vortex-acoustic feedback loop is decoupled. Consequently, both the vortex shedding and acoustic amplitudes decrease rapidly. 展开更多
关键词 Combustion instability Pressure oscillation Solid rocket motor Vortex-acoustic coupling Vortex shedding
原文传递
Effect of perforation on flow past a conic cylinder at Re=100:vortex-shedding pattern and force history 被引量:4
12
作者 L.M.Lin X.F.Zhong Y.X.Wu 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2018年第2期238-256,共19页
The flow past a circular-section cylinder with a conic shroud perforated with four holes at the peak was simulated numerically at Re = 100, considering two factors, viz.the angle of attack and the diameter of the hole... The flow past a circular-section cylinder with a conic shroud perforated with four holes at the peak was simulated numerically at Re = 100, considering two factors, viz.the angle of attack and the diameter of the holes. The effects of the perforated conic shroud on the vortex shedding pattern in the near wake was mainly investigated, as well as the time history of the drag and lift forces. In the investigated parameter space, three flow regimes were generally identified, corresponding to weak, moderate, and strong disturbance effects.In regime I, the wake can mainly be described by alternately shedding Kármán or Kármán-like vortices. In regime II, the spanwise vortices are obviously disturbed along the span due to the appearance of additional vorticity components and their interactions with the spanwise vortices, but still shed in synchronization along the spanwise direction. In regime III,the typical Kármán vortices partially or totally disappear,and some new vortex shedding patterns appear, such as-type, obliquely shedding, and crossed spanwise vortices with opposite sign. Corresponding to these complex vortex shedding patterns in the near wake, the fluid forces no longer oscillate regularly at a single vortex shedding frequency, but rather with a lower modulation frequency and multiple amplitudes. An overview of these flow regimes is presented. 展开更多
关键词 Vortex shedding pattern Fluid forces Flow control Conical shroud PERFORATION
在线阅读 下载PDF
Analysis and Design of Conjugate Cam Shedding Mechanism with Dual Driving Shafts 被引量:5
13
作者 蒋秀明 《Journal of China Textile University(English Edition)》 EI CAS 1998年第1期57-60,共4页
The principle of conjugate cam shedding mechanism forthe outside tappets with dual driving shafts is discussed,and its design conditions and parameters are studied,giving the results of practical calculations finally.
关键词 CONJUGATE CAM DUAL driving shedding MECHANISM
在线阅读 下载PDF
Flow Past an Accumulator Unit of an Underwater Energy Storage System: Three Touching Balloons in a Floral Configuration 被引量:4
14
作者 Ahmadreza Vasel-Be-Hagh Rupp Carriveau David S-K Ting 《Journal of Marine Science and Application》 2014年第4期467-476,共10页
An LES simulation of flow over an accumulator unit of an underwater compressed air energy storage facility was conducted. The accumulator unit consists of three touching underwater balloons arranged in a floral config... An LES simulation of flow over an accumulator unit of an underwater compressed air energy storage facility was conducted. The accumulator unit consists of three touching underwater balloons arranged in a floral configuration. The structure of the flow was examined via three dimensional iso surfaces of the Q criterion. Vortical cores were observed on the leeward surface of the balloons. The swirling tube flows generated by these vortical cores were depicted through three dimensional path lines. The flow dynamics were visualized via time series snapshots of two dimensional vorticity contours perpendicular to the flow direction; revealing the turbulent swinging motions of the aforementioned shedding-swirling tube flows. The time history of the hydrodynamic loading was presented in terms of lift and drag coefficients. Drag coefficient of each individual balloon in the floral configuration was smaller than that of a single balloon. It was found that the total drag coefficient of the floral unit of three touching balloons, i.e. summation of the drag coefficients of the balloons, is not too much larger than that of a single balloon whereas it provides three times the storage capacity. In addition to its practical significance in designing appropriate foundation and supports, the instantaneous hydrodynamic loading was used to determine the frequency of the turbulent swirling-swinging motions of the shedding vortex tubes; the Strouhal number was found to be larger than that of a single sphere at the same Reynolds number. 展开更多
关键词 droplet-shaped bluff body LES swirling flow swinging flow shedding vortex tubes underwater balloons
在线阅读 下载PDF
Numerical Simulation of an Airfoil Electrothermal-Deicing-System in the Framework of a Coupled Moving-Boundary Method 被引量:3
15
作者 Miao Xin Guo Zhong Yihua Cao 《Fluid Dynamics & Materials Processing》 EI 2020年第6期1-30,共30页
A numerical method for the analysis of the electrothermal deicing system for an airfoil is developed taking into account mass and heat exchange at the moving boundary that separates the water film created due to dropl... A numerical method for the analysis of the electrothermal deicing system for an airfoil is developed taking into account mass and heat exchange at the moving boundary that separates the water film created due to droplet impingement and the ice accretion region.The method relies on a Eulerian approach(used to capture droplet dynamics)and an unsteady heat transfer model(specifically conceived for a multilayer electrothermal problem on the basis of the enthalpy theory and a phase-change correction approach).Through application of the continuous boundary condition for temperature and heat flux at the coupled movingboundary,several simulations of ice accretion,melting and shedding,runback water flow and refreezing phenomena during the electrothermal deicing process are conducted.Finally,the results are verified via comparison with experimental data.A rich set of data concerning the dynamic evolution of the distribution of surface temperature,water film height and ice shape is presented and critically discussed. 展开更多
关键词 Electrothermal deicing water film flow unsteady heat transfer ice recognition coupled moving-boundary ice shedding
在线阅读 下载PDF
Virus load and virus shedding of SARS-CoV-2 and their impact onpatient outcomes 被引量:2
16
作者 Pei-Fen Chen Xia-Xia Yu +13 位作者 Yi-Peng Liu Di Ren Min Shen Bing-Sheng Huang Jun-Ling Gao heng-Yang Huang Ming Wu Wei-Yan Wang Li Chen Xia Shi Zhao-Qing Wang Ying-Xia Liu Lei Liu Yong Liu 《World Journal of Clinical Cases》 SCIE 2020年第24期6252-6263,共12页
BACKGROUND Understanding a virus shedding patterns in body fluids/secretions is importantto determine the samples to be used for diagnosis and to formulate infectioncontrol measures.AIM To investigate the severe acute... BACKGROUND Understanding a virus shedding patterns in body fluids/secretions is importantto determine the samples to be used for diagnosis and to formulate infectioncontrol measures.AIM To investigate the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)shedding patterns and its risk factors.METHODS All laboratory-confirmed coronavirus disease 2019 patients with completemedical records admitted to the Shenzhen Third People’s Hospital from January28, 2020 to March 8, 2020 were included. Among 145 patients (54.5% males;median age, 46.1 years), three (2.1%) died. The bronco-alveolar lavage fluid(BALF) had the highest virus load compared with the other samples. The viralload peaked at admission (3.3 × 108 copies) and sharply decreased 10 d afteradmission.RESULTS The viral load was associated with prolonged intensive care unit (ICU) duration.Patients in the ICU had significantly longer shedding time compared to those inthe wards (P < 0.0001). Age > 60 years [hazard ratio (HR) = 0.6;95% confidenceinterval (CI): 0.4-0.9] was an independent risk factor for SARS-CoV-2 shedding,while chloroquine (HR = 22.8;95%CI: 2.3-224.6) was a protective factor.CONCLUSION BALF had the highest SARS-CoV-2 load. Elderly patients had higher virus loads,which was associated with a prolonged ICU stay. Chloroquine was associatedwith shorter shedding duration and increased the chance of viral negativity. 展开更多
关键词 COVID-19 Virus shedding Viral load Patient outcome China Infectious disease
暂未订购
INVESTIGATION OF VORTEX SHEDDING INDUCED HYDRODYNAMIC VIBRATION IN VORTEX STREET FLOWMETER 被引量:2
17
作者 Fu Xin,Xu Bing,Yang Huayong (State Key Laboratory of Fluid Power Transmission and Control,Zhejiang University) 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2001年第4期310-313,共4页
Vortex street flowmeter has been used in steady flow measurement for about three decades The benefits of this type of flowmeter include high accuracy,good linearty,wide measuring range,and excellent reliability Ho... Vortex street flowmeter has been used in steady flow measurement for about three decades The benefits of this type of flowmeter include high accuracy,good linearty,wide measuring range,and excellent reliability However,in unsteady flow measurement,the pressure disturbance as well as the noise from the system or surrounding can reduce the signal to noise ratio of the flowmeter seriously Aimed to use vortex street flowmeters in unsteady flow measurement,the characteristics of the vortex shedding induced hydrodynamic vibration around the prism bluff body in a vortex street flowmeter are investigated numerically and by expriments The results show that the hydrodynamic vibrations with 180° phase shift occur at the axisymmetric points of the channel around the bluff body The most intense vibration occurs at the points on the lateral faces close to the base of the prism The results provide therefore a useful reference for developing an anti interference vortex flowmeter using the different ial sensing technique. 展开更多
关键词 Vortex street flowmeter Vortex shedding induced hydrodynamic vibration Unsteady flow measurement Anti-interference performance
在线阅读 下载PDF
Role of ADAM10 and ADAM17 in CD16b Shedding Mediated by Different Stimulators 被引量:2
18
作者 Sha Guo Min Peng +1 位作者 Qing Zhao Wei Zhang 《Chinese Medical Sciences Journal》 CAS CSCD 2012年第2期73-79,共7页
Objective To investigate the main proteinases responsible for CD16b shedding under different stimulators. Methods HEK293 cell line stably expressing CD16b was constructed by lentivirus system. The cell line was then ... Objective To investigate the main proteinases responsible for CD16b shedding under different stimulators. Methods HEK293 cell line stably expressing CD16b was constructed by lentivirus system. The cell line was then overexpressed with a disintegrin and metalloproteinase 10 (ADAM10) or ADAM17, sup- pressed with short hairpin RNA of ADAM10 or ADAM I 7, and reconstituted with ADAM 10 or ADAM17, respectively. After each treatment, the cell line was stimulated with ionomycin or phorbol 12-myristate- 13-acetate (PMA) for 12 hours. The soluble CD 16b released from cell membrane was detected by immuno- precipition and immunoblot. Quantitation was then implemented to compare the amount of soluble CD 16b in cell supernatant after stimulation. Results HEK293 cell line stably expressing CD16b was successfully established. When CDI6b ex- pressing cell line was overexpressed with ADAM 10, shedding of CD 16b was increased after stimulation with ionomycin but not PMA; when the cell line overexpressed with ADAM I7, shedding of CDI6b was increased after stimulation with PMA but not ionomycin. Similarly, when ADAM10 was suppressed by short hairpin RNA, CD 16b shedding was decreased after stimulation with ionomycin; when ADAM 17 was suppressed by short hairpin RNA, CD16b shedding was decreased after stimulation with PMA. The shedding of CD16b was increased again when CD16b expressing cell line was reconstituted with ADAM10 and stimulated by ionomycin or reconstituted with ADAM 17 and stimulated by PMA. Conclusions Both ADAM10 and ADAM17 could shed CD16b, but they possess differed prefer- ences. ADAM10 is the main sheddase under stimulation of ionomycin, while ADAM17 is the main sheddase under stimulation of PMA. 展开更多
关键词 a disintegrin and metalloproteinase 10 a disintegrin and metalloproteinase 17 CD 16b shedding
在线阅读 下载PDF
Inhibitory role of TACE/ADAM17 cytotail in protein ectodomain shedding 被引量:2
19
作者 Liliana Pérez 《World Journal of Biological Chemistry》 CAS 2011年第11期246-251,共6页
AIM:To determine if the cytotail of the principal sheddase tumor necrosis factor-α converting enzyme (TACE;ADAM17) controls protein ectodomain shedding.METHODS:Site-directed mutagenesis was performed to derive TACE v... AIM:To determine if the cytotail of the principal sheddase tumor necrosis factor-α converting enzyme (TACE;ADAM17) controls protein ectodomain shedding.METHODS:Site-directed mutagenesis was performed to derive TACE variants. The resulting TACE expression plasmids with amino acid substitutions in the extracel-lular,cysteine-rich disintegrin domain (CRD) and/or deleted cytotail,along with an expression vector for the enhanced green fluorescence protein were transfected into shedding-defective M1 mutants stably expressing transmembrane L-selectin or transforming growth factor (TGF)-α. The expression levels of the TACE substrates at the cell surface were determined by flow cytometry. RESULTS:Consistent with published data,a single point mutation (C600Y) in the CRD led to shedding defi-ciency. However,removal of the cytotail from the C600Y TACE variant partially restored ectodomain cleavage of TGF-α and L-selectin. Cytotail-deleted mutants with any other substituting amino acid residues in place of Cys600 displayed similar function compared with tail-less C600Y TACE.CONCLUSION:The cytotail plays an inhibitory role,which becomes evident when it is removed from an enzyme with another mutation that affects the enzyme function. 展开更多
关键词 ADAM17 ECTODOMAIN shedding L-SELECTIN Tumor NECROSIS factor-α converting enzyme
暂未订购
Experimental Investigation on Cavitating Flow Shedding over an Axisymmetric Blunt Body 被引量:7
20
作者 HU Changli WANG Guoyu HUANG Biao 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2015年第2期387-393,共7页
Nowadays,most researchers focus on the cavity shedding mechanisms of unsteady cavitating flows over different objects,such as 2D/3D hydrofoils,venturi-type section,axisymmetric bodies with different headforms,and so o... Nowadays,most researchers focus on the cavity shedding mechanisms of unsteady cavitating flows over different objects,such as 2D/3D hydrofoils,venturi-type section,axisymmetric bodies with different headforms,and so on.But few of them pay attention to the differences of cavity shedding modality under different cavitation numbers in unsteady cavitating flows over the same object.In the present study,two kinds of shedding patterns are investigated experimentally.A high speed camera system is used to observe the cavitating flows over an axisymmetric blunt body and the velocity fields are measured by a particle image velocimetry(PIV)technique in a water tunnel for different cavitation conditions.The U-type cavitating vortex shedding is observed in unsteady cavitating flows.When the cavitation number is 0.7,there is a large scale cavity rolling up and shedding,which cause the instability and dramatic fluctuation of the flows,while at cavitation number of 0.6,the detached cavities can be conjunct with the attached part to induce the break-off behavior again at the tail of the attached cavity,as a result,the final shedding is in the form of small scale cavity and keeps a relatively steady flow field.It is also found that the interaction between the re-entrant flow and the attached cavity plays an important role in the unsteady cavity shedding modality.When the attached cavity scale is insufficient to overcome the re-entrant flow,it deserves the large cavity rolling up and shedding just as that at cavitation number of 0.7.Otherwise,the re-entrant flow is defeated by large enough cavity to induce the cavity-combined process and small scale cavity vortexes shedding just as that of the cavitation number of0.6.This research shows the details of two different cavity shedding modalities which is worthful and meaningful for the further study of unsteady cavitation. 展开更多
关键词 cavity shedding unsteady cavitating flows high-speed video camera PIV re-entrant flow
在线阅读 下载PDF
上一页 1 2 14 下一页 到第
使用帮助 返回顶部