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Effects of acupuncture needle modification on acupuncture analgesia
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作者 Ming-zhu Sun Xin Wang +5 位作者 Ying-chen Li Yu-hang Liu Yi Yu Liu-jie Ren Wei Gu Wei Yao 《Journal of Integrative Medicine》 2025年第1期66-78,共13页
Objective The analgesic effect of acupuncture has been widely accepted.Nevertheless,the mechanism behind its analgesic effect remains elusive,thus impeding the progress of research geared toward enhancing the analgesi... Objective The analgesic effect of acupuncture has been widely accepted.Nevertheless,the mechanism behind its analgesic effect remains elusive,thus impeding the progress of research geared toward enhancing the analgesic effect of acupuncture.This paper investigated the role of acupuncture needle surface textures on acupuncture’s analgesic effect by creating four experimental acupuncture needles with different patterns of surface augmentation.Methods Four types of acupuncture needles with different surface textures(the lined needle,circle needle,sandpaper needle,and threaded needle)were designed.Additionally,the force/torque measurement system used a robot arm and mechanical sensor to measure the force on the needle during insertion and manipulation.To perform acupuncture analgesia experiments,four experimental acupuncture needles and a normal needle were inserted into the Zusanli(ST36)acupoint of rats with inflammatory pain.By comparing the force and torque and the analgesic efficacy of the different acupuncture needles,these experiments tested the role of acupuncture needle body texture on acupuncture analgesia.Results The analgesic effects of different acupuncture needle body textures varied.Specifically,the force required to penetrate the skin with the lined needle was not greater than that for the normal needle;however,the needle with inscribed circles and the sandpaper-roughened needle both required greater force for insertion.Additionally,the torque of the lined needle reached 2×10^(-4)N·m under twisting manipulation,which was four times greater the torque of a normal needle(5×10^(-5)N·m).Furthermore,the lined needle improved pain threshold and mast cell degranulation rate compared to the normal needle.Conclusion Optimizing the texture of acupuncture needles can enhance acupuncture analgesia.The texture of our experimental acupuncture needles had a significant impact on the force needed to penetrate the skin and the torque needed to manipulate the needle;it was also linked to variable analgesic effects.This study provides a theoretical basis for enhancing the analgesic efficacy of acupuncture through the modification of needles and promoting the development of acupuncture therapy. 展开更多
关键词 Acupuncture needle Acupuncture needle modification Analgesic efficacy Pain threshold Mast cell degranulation
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Prospective randomized study comparing Franseen 22-gauge vs standard 22-gauge needle for endoscopic ultrasound guided sampling of pancreatic solid lesions
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作者 Gabriela F Paduani Leika M Felipe +6 位作者 Gustavo A De Paulo Luciano Lenz Bruno C Martins Sergio E Matuguma Adriana V Safatle-Ribeiro Evandro S De Mello Fauze Maluf-Filho 《World Journal of Gastrointestinal Endoscopy》 2025年第4期42-51,共10页
BACKGROUND This is a randomized study to compare the diagnostic accuracy of endoscopic ultrasound(EUS)-guided sampling of pancreatic solid lesions obtained with the 22-gauge Franseen(EUS-fine needle biopsy)vs the 22-g... BACKGROUND This is a randomized study to compare the diagnostic accuracy of endoscopic ultrasound(EUS)-guided sampling of pancreatic solid lesions obtained with the 22-gauge Franseen(EUS-fine needle biopsy)vs the 22-gauge standard needle(EUS-fine needle aspiration)without rapid onsite evaluation(ROSE),since,in most endoscopy units around the world ROSE is not routinely available.AIM To investigate the accuracy of EUS-guided sampling of pancreatic solid lesions obtained between two different needles without ROSE.METHODS Patients with a solid pancreatic were included.Patients were biopsied in a randomized order.The primary endpoint was the diagnostic sensitivity for pancreatic malignancy(PM).Secondary outcomes were adequacy of the sample,the mean tissue area,the mean tumor area,and the adverse event rate.RESULTS The final diagnosis was pancreatic adenocarcinoma in 38(76%),neuroendocrine tumor in 4(8%),chronic pancreatitis in 3(6%)patients.The sensitivity for PM with Franseen needle was 0.91[95%confidence interval(CI):0.80-0.98],vs 0.8(95%CI:0.67-0.91)(P=0.025)with standard needle.The specificity for PM did not differentiate.The accuracy of the standard needle for PM was 0.80(95%CI:0.66-0.90),and the Franseen group was 0.90(95%CI:0.78-0.97)(P=0.074).The technical success rates for the standard and Franseen needle groups were 94%(95%CI:0.83-0.99)and 100%(95%CI:0.92-1.00),respectively.The mean total tissue area in mm2(SD)was greater in the Franseen group,2.07(0.22)vs 1.16(0.17)(P<0.01).The mean tumor area in mm2(SD)was not different in Franseen group vs standard group,0.42(0.09)vs 0.47(0.09)(P=0.80).There were no adverse events.CONCLUSION The sensitivity for PM and mean total tissue area,was greater in the as compared with standard needle.The mean tumor area did not differ between the groups. 展开更多
关键词 Franseen needle Standard needle Endoscopic ultrasound Pancreatic solid lesions Rapid onsite evaluation
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Investigation of discharge regimes of silicon needle with short air gap
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作者 Yanyi WANG Yining GE +2 位作者 Yong CHEN Li WANG Xuandong LIU 《Plasma Science and Technology》 2025年第5期1-8,共8页
Semiconductor electronic devices are prone to charge accumulation during production and transportation,which usually causes device breakdown.Ionizers are widely used for electrostatic elimination,and utilizing semicon... Semiconductor electronic devices are prone to charge accumulation during production and transportation,which usually causes device breakdown.Ionizers are widely used for electrostatic elimination,and utilizing semiconductor silicon for the discharge needle material in ionizers can effectively prevent metal contamination.To investigate the discharge characteristics of silicon needles and their mode modulation mechanism,this study has established an experimental platform for silicon needle-plate discharge under positive polarity voltage.Discharge pulse parameters and optical signals were measured at varying electrode spacings.The experimental results reveal that silicon needle discharge progresses through four regimes:the spontaneous streamer,the periodic streamer,the cluster streamer,and the glow discharge.Among these,the pulse amplitude is most uniform and stable in the periodic streamer regime.In addition,shorter-gap discharge exhibits higher pulse amplitude and repetition frequency but is easier to transition into the filament regime.The formation process of a single pulse is closely related to the field strength in the ionization region near the needle tip.Hence,parameters such as the pulse rising edge time and falling edge time show minimal variation with voltage.The amount of charge generated per unit time is primarily influenced by the repetition frequency.Consequently,the electrostatic ionizer produces the highest,most stable,and most uniform charges if it operates in the periodic streamer regime. 展开更多
关键词 silicon needle discharge regime electrode spacing CHARGES
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The Application of Infusion Project Team in the Safety Risk Management of Indwelling Needle Use
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作者 Liumei Wei Wenjing Li +2 位作者 Huiyu Zhou Siyi Xian Xuemei Xi 《Journal of Clinical and Nursing Research》 2025年第1期293-298,共6页
Objective: To explore the effectiveness of applying an infusion project team in the safety risk management of indwelling needle use. Methods: A total of 200 patients who used intravenous indwelling needles during hosp... Objective: To explore the effectiveness of applying an infusion project team in the safety risk management of indwelling needle use. Methods: A total of 200 patients who used intravenous indwelling needles during hospital treatment from July to October 2022 were selected and randomly divided into an observation group and a control group, with 100 patients in each group. Patients in the control group received routine nursing methods, while those in the observation group were managed using the safety risk management method of the infusion project team. The tube blocking rate and tube removal rate were compared between the two groups. Results: The one-time puncture success rate and the standard implementation rate of intravenous indwelling needle use in the observation group were significantly higher than those in the control group. The total incidence of complications in the observation group was significantly lower than that in the control group, and patient satisfaction in the observation group was notably higher, with statistically significant differences (P < 0.05). Conclusion: The application of an infusion project team in the safety risk management of indwelling needle use is effective and has positive impacts on improving the one-time puncture success rate, the standard implementation rate of intravenous indwelling needle use, and patient satisfaction. It is a practice worth promoting in clinical settings. 展开更多
关键词 Infusion project team Indwelling needle use Safety risk management APPLICATION
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Dynamic Characteristic Analysis and Structural Optimization of Entire Double-Shaft-Driven Needle Punching Machine for C/C Crucible Preforms
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作者 SUN Zhihong DENG Qicai +4 位作者 QU Zhiyang WANG Zhenxi WANG Bing ZHANG Xi ZHANG Jingzhang 《Journal of Donghua University(English Edition)》 2025年第4期399-408,共10页
Double-shaft-driven needle punching machine is a specialized equipment designed for processing C/C crucible preforms.Its main needle punching module is operated by two sets of reciprocating crank-slider mechanisms.The... Double-shaft-driven needle punching machine is a specialized equipment designed for processing C/C crucible preforms.Its main needle punching module is operated by two sets of reciprocating crank-slider mechanisms.The intense vibration during needle punching not only generates huge noise,but also substantially reduces the quality of the preform.It is imperative to perform a dynamic analysis and optimization of the entire needle punching machine.In this paper,the three-dimensional(3D)model of the entire double-shaft-driven needle punching machine for C/C crucible preforms is established.Based on the modal analysis theory,the modal characteristics of the needle punching machine under various operating conditions are analyzed and its natural frequencies and vibration modes are determined.The harmonic response analysis is then employed to obtain the amplitude of the needle plate at different frequencies,and the structural weak points of the needle punching machine are identified and improved.The feasibility of the optimized scheme is subsequently reevaluated and verified.The results indicate that the first six natural frequencies of the machine increase,and the maximum amplitude of the needle plate decreases by 70.3%.The enhanced dynamic characteristics of the machine significantly improve its performance,enabling more efficient needle punching of C/C crucible preforms. 展开更多
关键词 needle punching machine dynamic characteristic modal analysis harmonic response analysis structural optimization
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Effect of pestle needle therapy on the posterior cervical muscle in a rabbit model of cervical spondylosis
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作者 WU Haoyang Liu Yuan +4 位作者 CHEN Yuzhou XIE Yizhou ZHONG Lei YU Yang FAN Xiaohong 《Journal of Traditional Chinese Medicine》 2025年第4期786-795,共10页
OBJECTIVE:To investigate the effect of pestle needle therapy(PNT)on the posterior cervical muscle(PCM)in a rabbit model of cervical spondylosis(CS)and explore the underlying mechanisms.METHODS:Rabbits were divided int... OBJECTIVE:To investigate the effect of pestle needle therapy(PNT)on the posterior cervical muscle(PCM)in a rabbit model of cervical spondylosis(CS)and explore the underlying mechanisms.METHODS:Rabbits were divided into control,CS modelsⅠandⅡ(CS1 and CS2),electroacupuncture(EA),PNTⅠandⅡ(PN1 and PN2),activator(AVT),and PNT combined with activator(C-AVT)groups.A long-term neck immobilization technique was used to establish a rabbit model of CS.Following completion of modeling,the EA group received electroacupuncture intervention,whereas the CS1,CS2,and C-AVT groups received PNT intervention.The AVT and C-AVT groups received local 740 Y-P injections into the PCM daily.The inflammatory injury to PCM was evaluated based on pain threshold,morphological changes,and interleukin(IL)-1β,IL-6,and tumor necrosis factor(TNF)-αlevels.PCM fibrosis was evaluated by measuring the positive area(PA)of collagen fibrils(CFs)and collagen type 1 alpha 1(Col1α1)using Masson's and immunohistochemical staining.Terminal deoxynucleotidyl transferase-mediated d UTP nick-end labeling assay and transmission electron microscopy were used to identify apoptotic cells and assess autophagy,respectively.Western blotting was used to determine B-cell lymphoma-2(Bcl-2),Bcl-2 associated X protein(Bax),cysteine aspartate-specific protease(caspase)-3,sequestosome-1(P62),microtubuleassociated protein light chain 3(LC3-Ⅰ/Ⅱ),phosphatidylinositol 3-kinase(PI3K),protein kinase B(AKT),and mammalian target of rapamycin(mTOR)levels.Real-time quantitative polymerase chain reaction was used to determine mRNA expression levels of PI3K,AKT,mTOR,autophagy protein(ATG),and ATG7.RESULTS:PNT alleviated PCM cell degeneration and necrosis,inhibited inflammatory cell infiltration,decreased IL-1β,IL-6,and TNF-αlevels,and decreased the PA of CFs and Col1α1.In the PN1 group,cell apoptosis in the PCM decreased,autophagy increased,Bcl-2 and LC3-Ⅱ/Ⅰlevels increased,Bax,Caspase-3,and P62 levels decreased,and the mRNA expression of ATG5 and ATG7 increased.PNT inhibits protein and mRNA expression of PI3K,AKT,and mTOR.Finally,the trend in the results of the rescue experiment was consistent with previous results.CONCLUSION:PNT inhibited apoptosis and promoted autophagy of PCM cells in CS rabbits and alleviated inflammation and fibrosis injury of PCM by inhibiting the PI3K/AKT/mTOR pathway. 展开更多
关键词 SPONDYLOSIS pestle needle phosphatidylinositol 3-kinase proto-oncogene proteins c-akt TOR serine-threonine kinases apoptosis autophagy
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Clinical Efficacy of Mongolian Medicine Silver Needle Combined with Cupping and Bloodletting Therapy in the Treatment of Cervical Spondylotic Radiculopathy(CSR)
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作者 Mei SHUANG Wentong BAI +1 位作者 Sarula WANG Galiba 《Medicinal Plant》 2025年第3期62-65,68,共5页
[Objectives]To observe the clinical efficacy of Mongolian medicine silver needle combined with cupping and bloodletting therapy in the treatment of cervical spondylotic radiculopathy(CSR).[Methods]A total of 120 patie... [Objectives]To observe the clinical efficacy of Mongolian medicine silver needle combined with cupping and bloodletting therapy in the treatment of cervical spondylotic radiculopathy(CSR).[Methods]A total of 120 patients diagnosed with CSR who received treatment at the International Mongolian Hospital of Inner Mongolia between October 2021 and October 2022 were selected and randomly divided into two groups:A test group and a control group,with 60 patients in each group.The patients in the test group received Mongolian medicine silver needle combined with cupping and bloodletting therapy,following the principles of syndrome differentiation in Mongolian medicine.In contrast,the patients in the control group received only the Mongolian medicine silver needle therapy.After treatment,the Mongolian medicine syndrome scores,visual analogue scale(VAS)scores,and total clinical therapeutic effects in the two groups of patients were compared both prior to and following the treatment.[Results]The improvement in VAS and Mongolian medicine syndrome scores in the test group was greater than that in the control group,with a statistically significant difference(P<0.05).The scores of the test group surpassed those of the control group,and this difference was also statistically significant(P<0.05).Furthermore,the overall therapeutic effect in the test group was 93.33%,which was markedly higher than 76.67%observed in the control group(P<0.05).[Conclusions]The therapeutic effect of Mongolian medicine silver needle combined with cupping and bloodletting therapy in the treatment of CSR is remarkable.This approach has demonstrated efficacy in alleviating patient pain and improving the functionality of the cervical vertebrae,thereby warranting clinical promotion and application. 展开更多
关键词 Cervical spondylotic RADICULOPATHY (CSR) MONGOLIAN medicine silver needle THERAPY CUPPING and BLOODLETTING THERAPY Clinical efficacy
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Single-incision laparoscopic herniorrhaphy needle treatment for pediatric inguinal hernia:Surgical outcome,postoperative complications,and serum inflammation effects
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作者 Xue-Qi Wang Chi-Huan Kong 《World Journal of Gastrointestinal Surgery》 2025年第4期83-91,共9页
BACKGROUND Laparoscopic surgery,with the advantage of less trauma,has been predominantly performed to treat pediatric inguinal hernia.However,the traditional three-port laparoscopic surgery remains extremely traumatic... BACKGROUND Laparoscopic surgery,with the advantage of less trauma,has been predominantly performed to treat pediatric inguinal hernia.However,the traditional three-port laparoscopic surgery remains extremely traumatic for children,whereas singleport laparoscopic surgery causes less damage to children than traditional laparoscopy.However,single-port laparoscopic surgery is more challenging;thus,studies on the effect of its application in pediatric inguinal hernia remain relatively limited.AIM To analyze the association of single-incision laparoscopic herniorrhaphy needle treatment with surgical outcomes,postoperative complications,and serum inflammation in pediatric inguinal hernia.METHODS This retrospective study included 113 pediatric patients with inguinal hernia who underwent surgery at the Children’s Hospital,Capital Institute of Pediatrics,from April 2022 to May 2023.Participants were categorized into the observation group(single-incision laparoscopic herniorrhaphy needle,n=60)and the control group(two-port laparoscopic surgery,n=53).Comparative analyses involved surgical duration,intraoperative blood loss,and length of hospital stay.C-reactive protein(CRP)and white blood cell count(WBC)levels were measured preoperatively and 24 hours postoperatively.Postoperative pain was evaluated with the face,legs,activity,cry,and Consolability scale.Further,the incidence of complications,recurrence,and reoperation rates was assessed.Logistic regression was employed to determine independent risk factors related to poor prognosis.RESULTS The observation group demonstrated significantly reduced intraoperative blood loss and shorter hospitalization compared to the control group(P<0.05).Both groups demonstrated increased CRP and WBC levels postoperatively,but the observation group exhibited significantly lower levels(P<0.05).Further,pain scores at 24 hours postoperatively were significantly lower in the observation group(P<0.05).Additionally,the observation group experienced fewer adverse events,recurrence rates,and reoperations compared to the control group(P<0.05).Logistic regression analysis determined increased postoperative stress markers and surgical technique as independent predictors of recurrence(P<0.05).CONCLUSION Single-incision laparoscopic herniorrhaphy needle treatment for pediatric inguinal hernia exhibits significant efficacy,effectively reduces postoperative complications,ensures a more concealed surgical incision,and promotes faster postoperative recovery than conventional two-port laparoscopy.This approach merits wider application. 展开更多
关键词 Single-incision laparoscopic herniorrhaphy needle Pediatric inguinal hernia Surgical outcome Postoperative complications Serum inflammation
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Effectiveness of combining Qingyanyin formulated granules(轻燕饮配方颗粒) with press needles in treating abdominal obesity:a multicenter randomized controlled trial
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作者 YE Wujie YANG Yawei +6 位作者 ZHANG Da TANG Ling CUI Minying FU Bin ZHANG Meng HU Xingang ZHAO Yan 《Journal of Traditional Chinese Medicine》 2025年第1期107-114,共8页
OBJECTIVE:To assess the efficacy and safety of the Qingyanyin formulated granules(轻燕饮配方颗粒,QYY),press needles(PN),and their combined application in addressing abdominal obesity(AO).This trial aims to offer a mor... OBJECTIVE:To assess the efficacy and safety of the Qingyanyin formulated granules(轻燕饮配方颗粒,QYY),press needles(PN),and their combined application in addressing abdominal obesity(AO).This trial aims to offer a more scientifically grounded therapeutic regimen for clinical interventions.METHODS:From March 2021 to July 2021,a multicenter,triple-blind,randomized 2×2 factorial design clinical trial was conducted across 7 centers in 4 major cities within China's mainland.The trial participants were patients diagnosed with AO.The trial followed a 1∶1∶1∶1 random allocation ratio,assigning participants to one of four groups:QYY placebo plus simulated press needles(SPN)(placebo+SPN),QYY plus SPN(QYY+SPN),QYY placebo plus PN(placebo+PN),and QYY plus PN(QYY+PN).The trial participants received treatment for 12 weeks.Observe the changes in waist circumference,body weight,body mass index(BMI),Beck Depression Inventory(BDI),Beck Anxiety Inventory(BAI)scores,and Pittsburgh Sleep Quality Index(PSQI)before and after treatment.RESULTS:The QYY+PN group exhibited significant improvements in waist circumference compared to placebo+PN[Difference=-1.59,95%CI(-3.03,-0.16)]and placebo+SPN groups[Difference=-2.01,95%CI(-3.46,-0.57)].QYY+PN demonstrated a significant advantage over placebo+SPN[Difference=-2.01,95%CI(-3.46,-0.57)],and no statistically significant interaction was observed between the two interventions(P>0.05).In terms of weight and BMI improvements,the QYY+PN,QYY+SPN,and the PN+placebo groups all experienced trending greater reductions in weight compared to the placebo group.In terms of the total scores of PSQI,BAI,and BDI,all four groups exhibited improvements compared to the baseline.Specifically,concerning the change in total PSQI scores,the QYY+PN group exhibited a greater reduction;Regarding the change in total BAI scores,the PN+placebo group demonstrated a greater decrease;As for the change in total BDI scores,the QYY+SPN group displayed a greater reduction.CONCLUSION:This study confirmed that QYY+PN can effectively reduce the waist circumference of patients with AO.Furthermore,the combined approach offers greater benefits than either treatment alone,all without any reported serious adverse events. 展开更多
关键词 obesity abdominal body mass index press needle randomized controlled trial Qingyanyin formulated granules
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Ocular perforating injury by an acupuncture needle:two cases reports
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作者 Hu-Ping Song Chun-Hua Li +3 位作者 Tao Chen Zhao-Liang Zhu Peng Duan Wen-Wen Duan 《International Journal of Ophthalmology(English edition)》 2025年第12期2400-2402,共3页
Dear Editor,We report two rare cases of ocular perforating injuries caused by acupuncture needles.Both cases were approved by the Ethics Committee of Xi’an People’s Hospital(Xi’an No.4 Hospital)(KJLL-Z-K-2023060).W... Dear Editor,We report two rare cases of ocular perforating injuries caused by acupuncture needles.Both cases were approved by the Ethics Committee of Xi’an People’s Hospital(Xi’an No.4 Hospital)(KJLL-Z-K-2023060).Written informed consents were obtained from the patients.Acupuncture is an integral part of traditional Chinese medicine,and is widely used for the treatment of systemic diseases and ophthalmologic diseases^([1-8]),such as paralysis caused by stroke^([4]),diabetes^([7]),dry eye disease^([8]),pigmentary degeneration of retina,macular degeneration,glaucoma,and optic atrophy^([6]).Improper acupuncture technique can lead to accidents. 展开更多
关键词 ethics committee case reports ocular diseases STROKE TREATMENT acupuncture needle traditional Chinese medicine ocular perforating injury
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改进型超声引导下针状可视肾镜(Needle perc)钬激光碎石术治疗肾下盏结石的临床评价:与输尿管软镜对比 被引量:8
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作者 吴辉 孔莹莹 +3 位作者 高江涛 陈松林 杨银毫 李纪华 《现代泌尿外科杂志》 CAS 2024年第4期302-305,共4页
目的比较改进型超声引导下针状可视肾镜(Needle perc)钬激光碎石术和输尿管软镜下钬激光碎石术治疗1~2 cm肾下盏结石的效果,为临床治疗方式的选择提供参考。方法回顾性分析2022年1月—2023年5月郑州市第一人民医院收治的60例肾内单发下... 目的比较改进型超声引导下针状可视肾镜(Needle perc)钬激光碎石术和输尿管软镜下钬激光碎石术治疗1~2 cm肾下盏结石的效果,为临床治疗方式的选择提供参考。方法回顾性分析2022年1月—2023年5月郑州市第一人民医院收治的60例肾内单发下盏结石(最大径1~2 cm)患者的临床资料,比较行输尿管软镜钬激光碎石术的30例患者(软镜组)和改进型超声引导下Needle perc钬激光碎石术的30例患者(Needle perc组)的临床资料。结果Needle perc组较软镜组的整体住院时间[(3.00±1.25)d vs.(4.00±1.25)d]、手术时间[(44.63±5.42)min vs.(48.50±7.24)min]和住院花费[(15518±441)元vs.(16872±903)元]均较少(P<0.05)。Needle perc组术后清石率高于软镜组[93.3%(28/30)vs.50.7%(15/30),P<0.001]。术后降钙素原(PCT)上升幅度低于软镜组[(0.02±0.01)vs.(0.12±0.18),P=0.007],而并发症发生率低于软镜组[3.3%(1/30)vs.26.7%(8/30),P=0.030]。结论对于1~2 cm的肾下盏单发结石,改进型超声引导下Needle perc钬激光碎石术清石率较高、并发症发生率低,安全且有效。 展开更多
关键词 肾结石 针状可视肾镜 钬激光碎石术 输尿管软镜 结石清除率
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World Federation of Acupuncture-Moxibustion Societies(WFAS)Technical Benchmark of Acupuncture and Moxibustion:Filiform Needle 被引量:2
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作者 Liang ZHOU Si-qi ZHANG +2 位作者 Meng FANG Gui-rong DONG Hong-sheng DONG 《World Journal of Acupuncture-Moxibustion》 CAS CSCD 2024年第3期231-236,共6页
On December 31,2023,World Federation of Acupuncture-Moxibustion Societies(WFAS)officially issued Technical Benchmark of Acupuncture and Moxibustion:Filiform Needle.This technical benchmark clarifies terms and definiti... On December 31,2023,World Federation of Acupuncture-Moxibustion Societies(WFAS)officially issued Technical Benchmark of Acupuncture and Moxibustion:Filiform Needle.This technical benchmark clarifies terms and definitions,operating procedures and requirements,safety requirements,etc.The promulgation and implementation of this technical benchmark would provide a standard for acupuncture practitioners to apply filiform needle in clinical practice,and may play a positive role in the safe use and promotion of filiform needle. 展开更多
关键词 ACUPUNCTURE Filiform needle Academicorganization International standards Technicaloperation Specification
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A rare case of IgG4-related pancreatitis diagnosed preoperatively by endoscopic ultrasound-guided fine needle aspiration
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作者 Jun-Feng Zhou Zhong Chen 《Hepatobiliary & Pancreatic Diseases International》 SCIE CAS CSCD 2024年第6期648-652,共5页
Immunoglobulin G4-related disease(IgG4-RD)can affect organs and tissues throughout the body.IgG4-related pancreatitis,also called type 1 autoimmune pancreatitis(AIP),occurs in 60%of patients with IgG4-RD[1].IgG4-relat... Immunoglobulin G4-related disease(IgG4-RD)can affect organs and tissues throughout the body.IgG4-related pancreatitis,also called type 1 autoimmune pancreatitis(AIP),occurs in 60%of patients with IgG4-RD[1].IgG4-related pancreatitis is a general inflammatory disease infiltrated by immunoglobulin IgG4-positive plasma cells.Typical images exhibit diffuse or partial pancreatic swelling with delayed enhancement and no obvious upstream duct dilation[2].However,type 1 AIP occasionally appears in atypical clinical images and clinically mimics other pancreatic neoplasms(PN),such as pancreatic cancer(PC),intraductal papillary mucinous neoplasms(IPMN)and neuroendocrine neoplasm.It is very important for physicians or surgeons to distinguish between AIP and PN because the diagnosis greatly influences the selection of therapeutic schedule.AIP frequently responds rather readily to corticosteroid therapy while other PNs may need operations.Although the diagnostic criteria of AIP have been proposed[3,4],it still lacks practical strategies to differentiate between AIP and PN,particularly localized AIP.Confirmative pathological diagnosis is still the gold standard,but open biopsy is relatively invasive.Endoscopic ultrasound-guided fine needle aspiration(EUS-FNA)is less invasive and has a relatively high accuracy rate for distinguishing the essence of PN. 展开更多
关键词 needle NEOPLASMS DIAGNOSIS
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Oral delivery of insulin by barbed microneedles actuated by intestinal peristalsis
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作者 Qin Yu Haisheng He +2 位作者 Jianping Qi Yi Lu Wei Wu 《Chinese Chemical Letters》 SCIE CAS CSCD 2024年第9期6-8,共3页
Oral formulations are always preferred to injections due to the advantages of high patient compliance,no biohazardous needle waste,and low requirements for administration skills.However,the presence of multiple gastro... Oral formulations are always preferred to injections due to the advantages of high patient compliance,no biohazardous needle waste,and low requirements for administration skills.However,the presence of multiple gastrointestinal(GI)barriers,including extreme gastric acidity and a broad pH gradient,digestive enzymes,thick and variable mucus layers,and tight junctions in the enteric epithelia,restricts the rate and extent of oral absorption.Only active ingredients with favorable physicochemical properties. 展开更多
关键词 needle EXTREME FORMULATION
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Assessment of Knowledge, Attitude and Practices among Healthcare Workers in a Tertiary Care Hospital on Needle Stick Injury
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作者 Komal Kanani Sangita Rajdev Summaiya Mullan 《Advances in Infectious Diseases》 CAS 2024年第2期487-495,共9页
Purpose: Needle-stick injury (NSI) is one of the most potential occupational hazards for healthcare workers because of the transmission of blood-borne pathogens. As per recent data, around 30 lakh healthcare workers s... Purpose: Needle-stick injury (NSI) is one of the most potential occupational hazards for healthcare workers because of the transmission of blood-borne pathogens. As per recent data, around 30 lakh healthcare workers sustain Needle stick injuries each year. This study was conducted to assess healthcare workers’ knowledge, attitude and practices regarding needle stick injury. Materials & Methods: A cross-sectional study was conducted in a Tertiary Care Hospital over the period of 3 months. The study population consisted of Intern Doctors, Post Graduate resident Doctors, Staff Nurses, laboratory technicians of Government Medical College and New Civil Hospital, Surat (n = 300). The data were collected using a self-administered questionnaire via the means of Google Forms. Questionnaire was made with prior review literature. The data obtained were entered and analysed in Microsoft Excel. Results: The prevalence of NSI in our study was 46%, with a higher prevalence among the PG residents (72%). Overall scores regarding knowledge and attitude were better in PG residents (knowledge score > 7 in 71% and Attitude Score > 7 in 68% of PG Residents). Even though the PG residents scored highest in the knowledge category, the majority of them suffered needle stick injuries as a result of poor practice scores. Among those who had NSI (n = 139/300), 70% of study participants had superficial injuries, only 9% reported the incident, 18% got medical attention within 2 hours of the incident, and 7% followed up to recheck their viral markers status. Most incidents of NSI were due to hypodermic needles while recapping needles. Conclusion: Exposure to needle stick injuries and their underreporting remains a common problem. It is imperative that healthcare workers receive regular training on the proper handling of sharp objects. We can also draw the conclusion that preventing NSIs requires putting knowledge into practice. 展开更多
关键词 needle Stick Injury KNOWLEDGE ATTITUDE Practice Healthcare Workers
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MXene Enhanced 3D Needled Waste Denim Felt for High‑Performance Flexible Supercapacitors
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作者 Wei Fan Qi Wang +8 位作者 Kai Rong Yang Shi Wanxi Peng Handong Li Zhanhu Guo Ben Bin Xu Hua Hou Hassan Algadi Shengbo Ge 《Nano-Micro Letters》 SCIE EI CAS CSCD 2024年第2期383-394,共12页
MXene,a transition metal carbide/nitride,has been prominent as an ideal electrochemical active material for supercapacitors.However,the low MXene load limits its practical applications.As environmental concerns and su... MXene,a transition metal carbide/nitride,has been prominent as an ideal electrochemical active material for supercapacitors.However,the low MXene load limits its practical applications.As environmental concerns and sustainable development become more widely recognized,it is necessary to explore a greener and cleaner technology to recycle textile by-products such as cotton.The present study proposes an effective 3D fabrication method that uses MXene to fabricate waste denim felt into ultralight and flexible supercapacitors through needling and carbonization.The 3D structure provided more sites for loading MXene onto Z-directional fiber bundles,resulting in more efficient ion exchange between the electrolyte and electrodes.Furthermore,the carbonization process removed the specific adverse groups in MXenes,further improving the specific capacitance,energy density,power density and electrical conductivity of supercapacitors.The electrodes achieve a maximum specific capacitance of 1748.5 mF cm-2 and demonstrate remarkable cycling stability maintaining more than 94%after 15,000 galvanostatic charge/discharge cycles.Besides,the obtained supercapacitors present a maximum specific capacitance of 577.5 mF cm^(-2),energy density of 80.2μWh cm^(-2)and power density of 3 mW cm^(-2),respectively.The resulting supercapacitors can be used to develop smart wearable power devices such as smartwatches,laying the foundation for a novel strategy of utilizing waste cotton in a high-quality manner. 展开更多
关键词 MXene 3D needled waste denim felt SUPERCAPACITORS CARBONIZATION
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Needle-perc超脉冲光纤铥激光碎石光纤周围温度变化的体外实验研究
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作者 丁天福 徐铮 +4 位作者 肖博 黄忠月 单中杰 张楠 李建兴 《临床泌尿外科杂志》 CAS 2024年第9期807-811,共5页
目的探究Needle-perc超脉冲光纤铥激光碎石过程中光纤周围温度变化的情况。方法利用体外肾结石模型,由同一名医生行Needle-perc激光碎石术,采用2个测温探头置于激光光纤两侧2 mm处,实时进行检测并记录。保持实验室温度25℃左右。灌流液... 目的探究Needle-perc超脉冲光纤铥激光碎石过程中光纤周围温度变化的情况。方法利用体外肾结石模型,由同一名医生行Needle-perc激光碎石术,采用2个测温探头置于激光光纤两侧2 mm处,实时进行检测并记录。保持实验室温度25℃左右。灌流液采用生理盐水,温度22℃左右。灌流速度:0、25、50、100 mL/min。碎石功率:8、10、12、15 W,参数组合:“高能低频”模式和“高频低能”模式。间断激发:激发15 s,间断5 s,每组实验周期为120 s;连续激发:连续激发120 s,每组实验重复10次,温度记录仪实时记录温度。结果碎石功率为8、10、12、15 W时,灌流速度为0 mL/min时,温度超过安全阈值的时间分别是连续激发模式:23、18、13、9 s,间断激发模式:30、24、13、9 s。灌流速度为25、50、100 mL/min时,无论哪种激发模式,温度都没超过安全阈值。碎石功率为8、10、12、15 W,灌流速度25 mL/min时,“高能低频”碎块化模式和“高频低能”粉末化模式光纤周围温度变化值相比较,“高频低能”温度变化值高于“高能低频”模式,差异有统计学意义(P<0.05)。碎石功率为8、10、12、15 W,灌流速度25 mL/min时,连续激发和间断激发模式光纤周围温度变化值相比较,连续激发模式温度变化值温度高于间断激发,差异有统计学意义(P<0.05)。结论Needle-perc超脉冲光纤铥激光进行碎石时,连续激发模式温度变化值高于间断激发,“高频低能”参数组合温度变化值高于“高能低频”参数组合。但在碎石功率在≤15 W,灌注速度在≥25 mL/min时,无论哪种激发模式、参数组合,激光光纤周围的温度都是安全、可靠的。 展开更多
关键词 肾结石 needle-perc 温度 超脉冲铥激光
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Is magnesium deficiency the major cause of needle chlorosis of Pinus taeda in Brazil?
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作者 Antônio Carlos Vargas Motta Shizuo Maeda +6 位作者 Valdécio dos Santos dos Santos Rodrigues Tamires Maiara Ercole Stephen Arthur Prior Ana Elisa Lyra Brumat Amanda Pacheco Cardoso Moura Julierme Zimmer Barbosa João Bosco Vasconcellos Gomes 《Journal of Forestry Research》 SCIE EI CAS CSCD 2024年第2期209-221,共13页
Needle chlorosis(NC)in Pinus taeda L.systems in Brazil becomes more frequent after second and third harvest rotation cycles.In a study to identify factors contributing to yellowing needle chorosis(YNC),trees were grow... Needle chlorosis(NC)in Pinus taeda L.systems in Brazil becomes more frequent after second and third harvest rotation cycles.In a study to identify factors contributing to yellowing needle chorosis(YNC),trees were grown in soils originating from contrasting parent materials,and soils and needles(whole,green and chlorotic portions)from 1-and 2-year-old branches and the first and second needle flush release at four sites with YNC on P.taeda were analyzed for various elements and properties.All soils had very low base levels(Ca^(2+),Mg^(2+)and K^(+))and P,suggesting a possible lack of multiple elements.YNC symptoms started at needle tips,then extended toward the needle base with time.First flush needles had longer portions with YNC than second flush needles did.Needles from the lower crown also had more symptoms along their length than those higher in the canopy.Symptoms were similar to those reported for Mg.In chlorotic portions,Mg and Ca concentrations were well below critical values;in particular,Mg levels were only one third of the critical value of 0.3 g kg^(-1).Collectively,results suggest that Mg deficiency is the primary reason for NC of P.taeda in various parent soils in Brazil. 展开更多
关键词 Nutritional deficiency Forest management Soil depletion Pine foliar analysis needle chlorosis
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Time-resolved characteristics of a nanosecond pulsed multi-hollow needle plate packed bed dielectric barrier discharge
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作者 秦亮 李瑶 +6 位作者 郭浩 姜楠 宋颖 贾锐 周雄峰 袁皓 杨德正 《Plasma Science and Technology》 SCIE EI CAS CSCD 2024年第7期48-57,共10页
In this paper,self-designed multi-hollow needle electrodes are used as a high-voltage electrode in a packed bed dielectric barrier discharge reactor to facilitate fast gas flow through the active discharge area and ac... In this paper,self-designed multi-hollow needle electrodes are used as a high-voltage electrode in a packed bed dielectric barrier discharge reactor to facilitate fast gas flow through the active discharge area and achieve large-volume stable discharge.The dynamic characteristics of the plasma,the generated active species,and the energy transfer mechanisms in both positive discharge(PD)and negative discharge(ND)are investigated by using fast-exposure intensified charge coupled device(ICCD)images and time-resolved optical emission spectra.The experimental results show that the discharge intensity,number of discharge channels,and discharge volume are obviously enhanced when the multi-needle electrode is replaced by a multihollow needle electrode.During a single voltage pulse period,PD mainly develops in a streamer mode,which results in a stronger discharge current,luminous intensity,and E/N compared with the diffuse mode observed in ND.In PD,as the gap between dielectric beads changes from 0 to250μm,the discharge between the dielectric bead gap changes from a partial discharge to a standing filamentary micro-discharge,which allows the plasma to leave the local area and is conducive to the propagation of surface streamers.In ND,the discharge only appears as a diffusionlike mode between the gap of dielectric beads,regardless of whether there is a discharge gap.Moreover,the generation of excited states N_(2)^(+)(B^(2)∑_(u)^(+))and N2(C^(3)Π_(u))is mainly observed in PD,which is attributed to the higher E/N in PD than that in ND.However,the generation of the OH(A^(2)∑^(+))radical in ND is higher than in PD.It is not directly dominated by E/N,but mainly by the resonant energy transfer process between metastable N_(2)(A^(3)∑_(u)^(+))and OH(X^(2)Π).Furthermore,both PD and ND demonstrate obvious energy relaxation processes of electron-to-vibration and vibration-to-vibration,and no vibration-to-rotation energy relaxation process is observed. 展开更多
关键词 packed bed reactor multi-hollow needle electrodes positive and negative discharges optical emission spectra time-resolved images
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A Set of Acupuncture Needles in the Late Qing Dynasty Collected by George Souliéde Morant
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作者 WANG Han PANG Yichao +1 位作者 ZENG Ruilin WU Kai 《Chinese Medicine and Culture》 2024年第3期233-240,共8页
In the early 20th century,French vice-consul George Souliéde Morant encountered acupuncture during his visit to China,and then brought it back to France.After more than a century,his collection was transported fr... In the early 20th century,French vice-consul George Souliéde Morant encountered acupuncture during his visit to China,and then brought it back to France.After more than a century,his collection was transported from Paris,France to Kunming,China,and later recognized as a Chinese national third-class precious cultural heritage.Currently housed in the Museum of Western Studies on Chinese Medicine at Yunnan University of Chinese Medicine,this set of instruments includes one needle holder converted from a fan-shaped holder,ten acupuncture needles,and eleven paper tags handwritten in English with names of diseases and body parts.This article attempts to present the foundational information and historical significance of this collection of this set of late Qing dynasty acupuncture instruments by reviewing the collection and related research on acupuncture instruments,consulting acupuncture professionals,measuring the detailed information of the set of instruments,and employing a method of translating and summarizing the content of the attached tags. 展开更多
关键词 George Souliéde Morant Qing dynasty Acupuncture needles Traditional Chinese medicine FRANCE Tags
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