Particle size distribution of coarse aggregates through mechanical sieving gives results in terms of cumu- lative mass percent. But digital image processing generated size distribution of particles, while being fast a...Particle size distribution of coarse aggregates through mechanical sieving gives results in terms of cumu- lative mass percent. But digital image processing generated size distribution of particles, while being fast and accurate, is often expressed in terms of area function or number of particles. In this paper, a mass model is developed which converts the image obtained size distribution to mass-wise distribution, mak- ing it readily comparable to mechanical sieving data. The concept of weight/particle ratio is introduced for mass reconstruction from 2D images of particle aggregates. Using this mass model, the effects of several particle shape parameters (such as major axis, minor axis, and equivalent diameter) on sieve-size of the particles is studied. It is shown that the sieve-size of a particle strongly depend upon the shape param- eters, 91% of its variation being explained by major axis, minor axis, bounding box length and equivalent diameter. Furthermore, minor axis gives an overall accurate estimate of particle sieve-size, error in mean size (D-50) being just 0.4%. However, sieve-size of smaller particles (〈20 ram) strongly depends upon the length of the smaller arm of the bounding box enclosing them and sieve-sizes of larger particles (〉20 mm) are highly correlated to their equivalent diameters. Multiple linear regression analysis has been used to generate overall mass-wise particle size distribution, considering the influences of all these shape parameters on particle sieve-size. Multiple linear regression generated overall mass-wise particle size distribution shows a strong correlation with sieve generated data. The adjusted R-square value of the regression analysis is found to be 99 percent (w.r,t cumulative frequency). The method proposed in this paper provides a time-efficient way of producing accurate (up to 99%) mass-wise PSD using digital image processing and it can be used effectively to renlace the mechanical sieving.展开更多
AIM: To identify findings concerning white matter(WM) fibre microstructural alterations in anorexia nervosa(AN).METHODS: A systematic electronic search was undertaken in several databases up to April 2015. The search ...AIM: To identify findings concerning white matter(WM) fibre microstructural alterations in anorexia nervosa(AN).METHODS: A systematic electronic search was undertaken in several databases up to April 2015. The search strategy aimed to locate all studies published in English or Spanish that included participants with AN and which investigated WM using diffusion tensor imaging(DTI). Trials were assessed for quality assessment according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses checklist and a published quality index guideline. RESULTS: A total of 6 studies met the inclusion criteria, four of people in the acute state of the illness, one included both recovered and unwell participants, and one included people who had recovered. Participants were female with ages ranging from 14 to 29 years. All studies but one measured a range of psychopathological features. Fractional anisotropy and mean diffusivity were the main DTI correlates reported. Alterations were reported in a range of WM structures of the limbicsystem, most often of the fornix and cingulum as well as the fronto-occipital fibre tracts, i.e., regions associated with anxiety, body image and cognitive function. Subtle abnormalities also appeared to persist after recovery.CONCLUSION: This diversity likely reflects the symptom complexity of AN. However, there were few studies, they applied different methodologies, and all were cross-sectional.展开更多
Dynamic stress intensity factors are evaluated for thick-walled cylinder with a radial edge crack under internal impulsive pressure. Firstly, the equation for stress intensity factors under static uniform pressure is ...Dynamic stress intensity factors are evaluated for thick-walled cylinder with a radial edge crack under internal impulsive pressure. Firstly, the equation for stress intensity factors under static uniform pressure is used as the reference case, and then the weight function for a thick-walled cylinder containing a radial edge crack can be worked out. Secondly, the dynamic stresses in uncracked thick-walled cylinders are solved under internal impulsive pressure by using mode shape function method. The solution consists of a quasi-static solution satisfying inhomogeneous boundary conditions and a dynamic solution satisfying homogeneous boundary condi- tions, and the history and distribution of dynamic stresses in thick-walled cylinders are derived in terms of Fourier-Bessel series. Finally, the dynamic stress intensity factor equations for thick-walled cylinder containing a radial edge crack sub- jected to internal impulsive pressure are given by dynamic weight function method. The finite element method is utilized to verify the results of numerical examples, showing the validity and feasibility of the proposed method.展开更多
RNA-binding proteins(RBPs)are components of the post-transcriptional regulatory system,but their regulatory effects on complex traits remain unknown.Using an integrated strategy involving map-based cloning,functional ...RNA-binding proteins(RBPs)are components of the post-transcriptional regulatory system,but their regulatory effects on complex traits remain unknown.Using an integrated strategy involving map-based cloning,functional characterizations,and transcriptomic and population genomic analyses,we revealed that RBP-K(LOC_Os08g23120),RBP-A(LOC_Os11g41890),and RBP-J(LOC_Os10g33230)encode proteins that form an RBP-A-J-K complex that negatively regulates rice yield-related traits.Examinations of the RBP-A-J-K complex indicated RBP-K functions as a relatively non-specific RBP chaperone that enables RBP-A and RBP-J to function normally.Additionally,RBP-J most likely affects GA pathways,resulting in considerable increases in grain and panicle lengths,but decreases in grain width and thickness.In contrast,RBP-A negatively regulates the expression of genes most likely involved in auxin-regulated pathways controlling cell wall elongation and carbohydrate transport,with substantial effects on the rice grain filling process as well as grain length and weight.Evolutionarily,RBP-K is relatively ancient and highly conserved,whereas RBP-J and RBP-A are more diverse.Thus,the RBP-A-J-K complex may represent a typical functional model for many RBPs and protein complexes that function at transcriptional and post-transcriptional levels in plants and animals for increased functional consistency,efficiency,and versatility,as well as increased evolutionary potential.Our results clearly demonstrate the importance of RBP-mediated post-transcriptional regulation for the diversity of complex traits.Furthermore,rice grain yield and quality may be enhanced by introducing various complete or partial loss-of-function mutations to specific RBP genes using clustered regularly interspaced palindromic repeats(CRISPR)/CRISPR-associated protein 9 technology and by exploiting desirable natural tri-genic allelic combinations at the loci encoding the components of the RBP-A-J-K complex through marker-assisted selection.展开更多
With the rapid development of the shipping industry,the safety and comfort of ship transportation have been paid more and more attention,and the pitch and heave motion of ships are the most serious factors.In this pap...With the rapid development of the shipping industry,the safety and comfort of ship transportation have been paid more and more attention,and the pitch and heave motion of ships are the most serious factors.In this paper,the longitudinal motion mathematical model of YuKun is esta b lished.By assigning the zero-pole to the left half-plane and using the properties of the symmetric matrix,the shaping weighting functions matrix is designed to stabilize the multi-input multi-output(MIMO)system of YuKun.Finally,a new concise robust controller is designed using the steady output of the shaped system.The simulation results show that under the control of the concise robust controller,the pitch angle and heave of YuKun decrease by 79.9% and 86.2%,respectively.Theoretical analysis and simulation results show that the concise robust controller has a good control effect on the longitudinal motion of YuKun,and is simple and easy to use,with clear engineering significance.展开更多
基金Indian Institute of Technology,Kharagpur in India for supporting this work
文摘Particle size distribution of coarse aggregates through mechanical sieving gives results in terms of cumu- lative mass percent. But digital image processing generated size distribution of particles, while being fast and accurate, is often expressed in terms of area function or number of particles. In this paper, a mass model is developed which converts the image obtained size distribution to mass-wise distribution, mak- ing it readily comparable to mechanical sieving data. The concept of weight/particle ratio is introduced for mass reconstruction from 2D images of particle aggregates. Using this mass model, the effects of several particle shape parameters (such as major axis, minor axis, and equivalent diameter) on sieve-size of the particles is studied. It is shown that the sieve-size of a particle strongly depend upon the shape param- eters, 91% of its variation being explained by major axis, minor axis, bounding box length and equivalent diameter. Furthermore, minor axis gives an overall accurate estimate of particle sieve-size, error in mean size (D-50) being just 0.4%. However, sieve-size of smaller particles (〈20 ram) strongly depends upon the length of the smaller arm of the bounding box enclosing them and sieve-sizes of larger particles (〉20 mm) are highly correlated to their equivalent diameters. Multiple linear regression analysis has been used to generate overall mass-wise particle size distribution, considering the influences of all these shape parameters on particle sieve-size. Multiple linear regression generated overall mass-wise particle size distribution shows a strong correlation with sieve generated data. The adjusted R-square value of the regression analysis is found to be 99 percent (w.r,t cumulative frequency). The method proposed in this paper provides a time-efficient way of producing accurate (up to 99%) mass-wise PSD using digital image processing and it can be used effectively to renlace the mechanical sieving.
文摘AIM: To identify findings concerning white matter(WM) fibre microstructural alterations in anorexia nervosa(AN).METHODS: A systematic electronic search was undertaken in several databases up to April 2015. The search strategy aimed to locate all studies published in English or Spanish that included participants with AN and which investigated WM using diffusion tensor imaging(DTI). Trials were assessed for quality assessment according to the Preferred Reporting Items for Systematic Reviews and Meta-analyses checklist and a published quality index guideline. RESULTS: A total of 6 studies met the inclusion criteria, four of people in the acute state of the illness, one included both recovered and unwell participants, and one included people who had recovered. Participants were female with ages ranging from 14 to 29 years. All studies but one measured a range of psychopathological features. Fractional anisotropy and mean diffusivity were the main DTI correlates reported. Alterations were reported in a range of WM structures of the limbicsystem, most often of the fornix and cingulum as well as the fronto-occipital fibre tracts, i.e., regions associated with anxiety, body image and cognitive function. Subtle abnormalities also appeared to persist after recovery.CONCLUSION: This diversity likely reflects the symptom complexity of AN. However, there were few studies, they applied different methodologies, and all were cross-sectional.
基金supported by the China Aviation Industry Corporation I Program (ATPD-1104-02).
文摘Dynamic stress intensity factors are evaluated for thick-walled cylinder with a radial edge crack under internal impulsive pressure. Firstly, the equation for stress intensity factors under static uniform pressure is used as the reference case, and then the weight function for a thick-walled cylinder containing a radial edge crack can be worked out. Secondly, the dynamic stresses in uncracked thick-walled cylinders are solved under internal impulsive pressure by using mode shape function method. The solution consists of a quasi-static solution satisfying inhomogeneous boundary conditions and a dynamic solution satisfying homogeneous boundary condi- tions, and the history and distribution of dynamic stresses in thick-walled cylinders are derived in terms of Fourier-Bessel series. Finally, the dynamic stress intensity factor equations for thick-walled cylinder containing a radial edge crack sub- jected to internal impulsive pressure are given by dynamic weight function method. The finite element method is utilized to verify the results of numerical examples, showing the validity and feasibility of the proposed method.
基金supported by the Innovation Program of Shanghai Municipal Education Commission(2023ZKZD05)the National Natural Science Foundation of China(32172043,31971918 and 32170356)+2 种基金the Shanghai Science and Technology Innovation Action Plan Project(22N11900200)the Innovation Program of Chinese Academy of Agricultural Sciencesthe grant from the National Key Research and Development Program of China(2021YFA1300401).
文摘RNA-binding proteins(RBPs)are components of the post-transcriptional regulatory system,but their regulatory effects on complex traits remain unknown.Using an integrated strategy involving map-based cloning,functional characterizations,and transcriptomic and population genomic analyses,we revealed that RBP-K(LOC_Os08g23120),RBP-A(LOC_Os11g41890),and RBP-J(LOC_Os10g33230)encode proteins that form an RBP-A-J-K complex that negatively regulates rice yield-related traits.Examinations of the RBP-A-J-K complex indicated RBP-K functions as a relatively non-specific RBP chaperone that enables RBP-A and RBP-J to function normally.Additionally,RBP-J most likely affects GA pathways,resulting in considerable increases in grain and panicle lengths,but decreases in grain width and thickness.In contrast,RBP-A negatively regulates the expression of genes most likely involved in auxin-regulated pathways controlling cell wall elongation and carbohydrate transport,with substantial effects on the rice grain filling process as well as grain length and weight.Evolutionarily,RBP-K is relatively ancient and highly conserved,whereas RBP-J and RBP-A are more diverse.Thus,the RBP-A-J-K complex may represent a typical functional model for many RBPs and protein complexes that function at transcriptional and post-transcriptional levels in plants and animals for increased functional consistency,efficiency,and versatility,as well as increased evolutionary potential.Our results clearly demonstrate the importance of RBP-mediated post-transcriptional regulation for the diversity of complex traits.Furthermore,rice grain yield and quality may be enhanced by introducing various complete or partial loss-of-function mutations to specific RBP genes using clustered regularly interspaced palindromic repeats(CRISPR)/CRISPR-associated protein 9 technology and by exploiting desirable natural tri-genic allelic combinations at the loci encoding the components of the RBP-A-J-K complex through marker-assisted selection.
基金This work is partially supported by the National Science Foundation of China(Grant No.51679024)Dalian Innovation TeamSupport Plan in the Key Research Field(Grant No.2020RT08)The Funda mental Research Funds for the Central Universities(Grant No.3132021139)。
文摘With the rapid development of the shipping industry,the safety and comfort of ship transportation have been paid more and more attention,and the pitch and heave motion of ships are the most serious factors.In this paper,the longitudinal motion mathematical model of YuKun is esta b lished.By assigning the zero-pole to the left half-plane and using the properties of the symmetric matrix,the shaping weighting functions matrix is designed to stabilize the multi-input multi-output(MIMO)system of YuKun.Finally,a new concise robust controller is designed using the steady output of the shaped system.The simulation results show that under the control of the concise robust controller,the pitch angle and heave of YuKun decrease by 79.9% and 86.2%,respectively.Theoretical analysis and simulation results show that the concise robust controller has a good control effect on the longitudinal motion of YuKun,and is simple and easy to use,with clear engineering significance.