The Paleoproterozoic basement of Zoukougbeu in central-western Côte d’Ivoire lies within the southern Baoulé-Mossi domain of the West African Craton,a key area for understanding the crustal evolution associ...The Paleoproterozoic basement of Zoukougbeu in central-western Côte d’Ivoire lies within the southern Baoulé-Mossi domain of the West African Craton,a key area for understanding the crustal evolution associated with the Eburnean orogeny.However,the petrogenesis and geodynamic context of the granitoid intrusions in this region remain poorly constrained,despite their potential sig nificance for regional crustal growth and mineralization.This study integrates petrographic and whole-rock geochemical data from drill-core samples to clar-ify the origin and tectonic evolution of these rocks.The lithological assemblage includes granodiorite,granite,diorite,gneiss,and pegmatite,variably deformed and hydrothermally altered.Petrographic analysis reveals plagioclase-quartzbiotiteamphibole assemblages overprinted by chlorite-epidote alteration,in-dicating greenschist-to amphibolite-facies metamorphism.Geochemically,the rocks define a calc-alkaline,metaluminous to slightly peraluminous suite with tonalite-trondhjemite-granodiorite(TTG)affinity.Their enrichment in largeion lithophile elements and depletion in Nb-Ta-Ti,coupled with LREE enrich-ment and negative Eu anomalies,are typical of subduction-related magmatism.These signatures indicate that the Zoukougbeu granitoids originated from par-tial melting of hydrated basaltic crust with minor mantle input in a continental volcanic-arc setting during the Eburnean orogeny(~2.1-2.0 Ga).This finding refines the current understanding of Paleoproterozoic crustal evolution in the southern West African Craton and highlights the role of arc magmatism in its stabilization.展开更多
Viral hepatitis represents a major danger to public health,and is a globally leading cause of death.The five liver-specific viruses:Hepatitis A virus,hepatitis B virus,hepatitis C virus,hepatitis D virus,and hepatitis...Viral hepatitis represents a major danger to public health,and is a globally leading cause of death.The five liver-specific viruses:Hepatitis A virus,hepatitis B virus,hepatitis C virus,hepatitis D virus,and hepatitis E virus,each have their own unique epidemiology,structural biology,transmission,endemic patterns,risk of liver complications,and response to antiviral therapies.There remain few options for treatment,in spite of the increasing prevalence of viral-hepatitiscaused liver disease.Furthermore,chronic viral hepatitis is a leading worldwide cause of both liver-related morbidity and mortality,even though effective treatments are available that could reduce or prevent most patients’complications.In 2016,the World Health Organization released its plan to eliminate viral hepatitis as a public health threat by the year 2030,along with a discussion of current gaps and prospects for both regional and global eradication of viral hepatitis.Today,treatment is sufficiently able to prevent the disease from reaching advanced phases.However,future therapies must be extremely safe,and should ideally limit the period of treatment necessary.A better understanding of pathogenesis will prove beneficial in the development of potential treatment strategies targeting infections by viral hepatitis.This review aims to summarize the current state of knowledge on each type of viral hepatitis,together with major innovations.展开更多
Vitamins are natural materials essential for maintaining the normal physical function of the live cells. It has been reported that 13 vitamins are needed in our body, included vitamin A, B vitamins （thiamine, ribofla...Vitamins are natural materials essential for maintaining the normal physical function of the live cells. It has been reported that 13 vitamins are needed in our body, included vitamin A, B vitamins （thiamine, riboflavin, niacin, pantothenic acid, pyridoxine, biotin, folic acid and cobalamin）, vitamin C, vitamin D, vitamin E and vitamin K. Nowadays, the functions of vitamins have been extensively investigated. The objective of this paper is to summarize the new functions of vitamins, aiming to provide suggestions on the usage of various vitamins in clinical application.展开更多
文摘The Paleoproterozoic basement of Zoukougbeu in central-western Côte d’Ivoire lies within the southern Baoulé-Mossi domain of the West African Craton,a key area for understanding the crustal evolution associated with the Eburnean orogeny.However,the petrogenesis and geodynamic context of the granitoid intrusions in this region remain poorly constrained,despite their potential sig nificance for regional crustal growth and mineralization.This study integrates petrographic and whole-rock geochemical data from drill-core samples to clar-ify the origin and tectonic evolution of these rocks.The lithological assemblage includes granodiorite,granite,diorite,gneiss,and pegmatite,variably deformed and hydrothermally altered.Petrographic analysis reveals plagioclase-quartzbiotiteamphibole assemblages overprinted by chlorite-epidote alteration,in-dicating greenschist-to amphibolite-facies metamorphism.Geochemically,the rocks define a calc-alkaline,metaluminous to slightly peraluminous suite with tonalite-trondhjemite-granodiorite(TTG)affinity.Their enrichment in largeion lithophile elements and depletion in Nb-Ta-Ti,coupled with LREE enrich-ment and negative Eu anomalies,are typical of subduction-related magmatism.These signatures indicate that the Zoukougbeu granitoids originated from par-tial melting of hydrated basaltic crust with minor mantle input in a continental volcanic-arc setting during the Eburnean orogeny(~2.1-2.0 Ga).This finding refines the current understanding of Paleoproterozoic crustal evolution in the southern West African Craton and highlights the role of arc magmatism in its stabilization.
基金Supported by the JSPS Kakenhi Grant,No.JP24K15491.
文摘Viral hepatitis represents a major danger to public health,and is a globally leading cause of death.The five liver-specific viruses:Hepatitis A virus,hepatitis B virus,hepatitis C virus,hepatitis D virus,and hepatitis E virus,each have their own unique epidemiology,structural biology,transmission,endemic patterns,risk of liver complications,and response to antiviral therapies.There remain few options for treatment,in spite of the increasing prevalence of viral-hepatitiscaused liver disease.Furthermore,chronic viral hepatitis is a leading worldwide cause of both liver-related morbidity and mortality,even though effective treatments are available that could reduce or prevent most patients’complications.In 2016,the World Health Organization released its plan to eliminate viral hepatitis as a public health threat by the year 2030,along with a discussion of current gaps and prospects for both regional and global eradication of viral hepatitis.Today,treatment is sufficiently able to prevent the disease from reaching advanced phases.However,future therapies must be extremely safe,and should ideally limit the period of treatment necessary.A better understanding of pathogenesis will prove beneficial in the development of potential treatment strategies targeting infections by viral hepatitis.This review aims to summarize the current state of knowledge on each type of viral hepatitis,together with major innovations.
文摘Vitamins are natural materials essential for maintaining the normal physical function of the live cells. It has been reported that 13 vitamins are needed in our body, included vitamin A, B vitamins （thiamine, riboflavin, niacin, pantothenic acid, pyridoxine, biotin, folic acid and cobalamin）, vitamin C, vitamin D, vitamin E and vitamin K. Nowadays, the functions of vitamins have been extensively investigated. The objective of this paper is to summarize the new functions of vitamins, aiming to provide suggestions on the usage of various vitamins in clinical application.
基金supported by the Natural Science Foundation of Hunan Province(2015JJ6120)the Health and Family Planning Research Foundation of Hunan Province(B2015-34)Development and Reform Commission Project of Hunan Province([2014]658),China
