Carbon nanotube fibers(CNTFs)fabricated using a novel“wet-pulling”technique were evaluated for electrochemical detection of dopamine(DA).To enhance the sensitivity,we employed an electrochemical oxidation pretreatme...Carbon nanotube fibers(CNTFs)fabricated using a novel“wet-pulling”technique were evaluated for electrochemical detection of dopamine(DA).To enhance the sensitivity,we employed an electrochemical oxidation pretreatment and twisting of CNTFs and investigated the performance by cyclic voltammetry(CV)and chronoamperometry(CA).The synergetic eff ect of twisting and pre-oxidation boosted the sensitivity of modified CNTFs compared to the as-obtained CNTFs due to the introduction of new active sites for efficient trapping of DA molecules.For the oxidized twisted CNTFs,we achieved a sensitivity of 10.8μA·μM^(–1)·cm^(–2)and the limit of detection of 330 nM in the case of CV,and 6.4μA·μM-1·cm-2and 102 nM in the case of CA,respectively.The CNTFs showed good potential for an in vitro application,maintaining sufficient sensitivity under various conditions.When coupled with the suited mechanical properties of CNTFs,the results highlight the prospect of implantable and flexible sensors.展开更多
基金supported by Russian Science Foundation,21-73-10288Ministry of Science and Higher Education of the Russian Federation,FZSR-2024-0005。
文摘Carbon nanotube fibers(CNTFs)fabricated using a novel“wet-pulling”technique were evaluated for electrochemical detection of dopamine(DA).To enhance the sensitivity,we employed an electrochemical oxidation pretreatment and twisting of CNTFs and investigated the performance by cyclic voltammetry(CV)and chronoamperometry(CA).The synergetic eff ect of twisting and pre-oxidation boosted the sensitivity of modified CNTFs compared to the as-obtained CNTFs due to the introduction of new active sites for efficient trapping of DA molecules.For the oxidized twisted CNTFs,we achieved a sensitivity of 10.8μA·μM^(–1)·cm^(–2)and the limit of detection of 330 nM in the case of CV,and 6.4μA·μM-1·cm-2and 102 nM in the case of CA,respectively.The CNTFs showed good potential for an in vitro application,maintaining sufficient sensitivity under various conditions.When coupled with the suited mechanical properties of CNTFs,the results highlight the prospect of implantable and flexible sensors.
