Biosensors based on organic electrochemical transistors(OECTs)have been a research highlight in recent years owing to their remarkable biocompatibility,low operating voltage,and substantial signal amplification capabi...Biosensors based on organic electrochemical transistors(OECTs)have been a research highlight in recent years owing to their remarkable biocompatibility,low operating voltage,and substantial signal amplification capability.Especially,as an emerging fundamental device for biosensing,OECTs show great potential for pH,ions,molecules,and biomarker sensing.This review highlights the research progress of biomolecule sensors based on OECTs,focusing on recent publications in the past 5 years.Specifically,OECT-based biomolecule sensors for small molecules(glucose,dopamine,lactate,etc.that act as signals or effectors),and macromolecules(DNA,RNA,proteins,etc.that are often used as markers in physiology and medicine),are summarized.Additionally,emerging technologies and materials used to enhance sensitivity,detection limits,and detection ranges are described comprehensively.Last,aspects of OECT-based biomolecule sensors that need further improvement are discussed along with future opportunities and challenges.展开更多
Remote passive drone detection in the presence of strong background noise is challenging,since they are point objects and cannot be recognized by their contour detection.In this study,we introduce a new passive single...Remote passive drone detection in the presence of strong background noise is challenging,since they are point objects and cannot be recognized by their contour detection.In this study,we introduce a new passive single-photon dynamic imaging method using quantum compressed sensing.This method utilizes the inherent randomness of photon radiation and detection to construct a compressive imaging system.It captures the broadband dynamic features of the point object through sparse photon detection,achieving a detectable bandwidth up to 2.05 GHz,which is significantly higher than current photon-counting imaging techniques.The method also shows excellent noise resistance,achieving high-quality imaging with a signal-to-background ratio of 1/332.This technique significantly enhances the use of single-photon imaging in real-world applications.展开更多
Capacitive Micromachined Ultrasonic Transducer(CMUT)are widely utilized in fields such as medical imaging,nondestructive testing,and chemical sensing for active sensing applications.However,the capacitive structure of...Capacitive Micromachined Ultrasonic Transducer(CMUT)are widely utilized in fields such as medical imaging,nondestructive testing,and chemical sensing for active sensing applications.However,the capacitive structure of CMUT also demonstrates significant potential in the domain of passive pressure sensing.This study is the first to apply the CMUT structure to passive pressure sensing in high hydrostatic pressure environments.The CMUT pressure sensor,fabricated using MEMS technology,demonstrates high consistency,with a maximum static capacitance deviation of only 1%among multiple sensors.Experimental results from high hydrostatic pressure testing indicate that the sensor can reliably measure pressures exceeding 20 MPa with real-time responsiveness.After being placed in a dynamic pressure chamber for three months,the sensor’s pressure measurements remained consistent with the initial results,exhibiting a maximum deviation of just 0.65%,demonstrating excellent repeatability.These experiments confirm the high reliability and outstanding long-term stability of the sensor,laying a foundation for CMUT structure applications in high hydrostatic pressure sensing.展开更多
基金supported by the National Key R&D Program of China(2023YFC2411800)the National Natural Science Foundation of China(62303094,62273073)+5 种基金the National Key R&D Program of China(2024YFB3211600,2022YFE0134800)the Natural Science Foundation of Sichuan(2025ZNSFSC0515)the Key Research Project of the Henan Educational Committee of China(24A413001)the Aeronautical Science Foundation of China(20230024080002)Chengdu Science and Technology Bureau(2023-YF06-00028-HZ)the Fundamental Research Funds for the Central Universities(ZYGX2024XJ029).
文摘Biosensors based on organic electrochemical transistors(OECTs)have been a research highlight in recent years owing to their remarkable biocompatibility,low operating voltage,and substantial signal amplification capability.Especially,as an emerging fundamental device for biosensing,OECTs show great potential for pH,ions,molecules,and biomarker sensing.This review highlights the research progress of biomolecule sensors based on OECTs,focusing on recent publications in the past 5 years.Specifically,OECT-based biomolecule sensors for small molecules(glucose,dopamine,lactate,etc.that act as signals or effectors),and macromolecules(DNA,RNA,proteins,etc.that are often used as markers in physiology and medicine),are summarized.Additionally,emerging technologies and materials used to enhance sensitivity,detection limits,and detection ranges are described comprehensively.Last,aspects of OECT-based biomolecule sensors that need further improvement are discussed along with future opportunities and challenges.
基金supported by Shanxi Province Science and Technology Major Special Project(202201010101005)the Natural Science Foundation of China(U22A2091,62105193,62127817,62075120,62075122,62222509,62205187,6191101445 and 62305200)+5 种基金China Postdoctoral Science Foundation(2022M722006)National Key Research and Development Program of China(2022YFA1404201)Shanxi Province Science and Technology Innovation Talent Team(No.202204051001014)Science and Technology Cooperation Project of Shanxi Province(202104041101021)Shanxi“1331 Project”111 projects(D18001).
文摘Remote passive drone detection in the presence of strong background noise is challenging,since they are point objects and cannot be recognized by their contour detection.In this study,we introduce a new passive single-photon dynamic imaging method using quantum compressed sensing.This method utilizes the inherent randomness of photon radiation and detection to construct a compressive imaging system.It captures the broadband dynamic features of the point object through sparse photon detection,achieving a detectable bandwidth up to 2.05 GHz,which is significantly higher than current photon-counting imaging techniques.The method also shows excellent noise resistance,achieving high-quality imaging with a signal-to-background ratio of 1/332.This technique significantly enhances the use of single-photon imaging in real-world applications.
基金funded by National Key Research and Development Program(2024YFF0510000)National Natural Science Foundation of China(Grant 62522125,U23A20362,62320106011,52275578)Baiyi Program of Shanxi Province.
文摘Capacitive Micromachined Ultrasonic Transducer(CMUT)are widely utilized in fields such as medical imaging,nondestructive testing,and chemical sensing for active sensing applications.However,the capacitive structure of CMUT also demonstrates significant potential in the domain of passive pressure sensing.This study is the first to apply the CMUT structure to passive pressure sensing in high hydrostatic pressure environments.The CMUT pressure sensor,fabricated using MEMS technology,demonstrates high consistency,with a maximum static capacitance deviation of only 1%among multiple sensors.Experimental results from high hydrostatic pressure testing indicate that the sensor can reliably measure pressures exceeding 20 MPa with real-time responsiveness.After being placed in a dynamic pressure chamber for three months,the sensor’s pressure measurements remained consistent with the initial results,exhibiting a maximum deviation of just 0.65%,demonstrating excellent repeatability.These experiments confirm the high reliability and outstanding long-term stability of the sensor,laying a foundation for CMUT structure applications in high hydrostatic pressure sensing.