AIM:To develop and test an Arabic version of the National Eye Institute Visual Function Questionnaire-25(NEI-VFQ-25).METHODS:NEI-VFQ-25 was translated into Arabic according to WHO translation guidelines. We enrolled a...AIM:To develop and test an Arabic version of the National Eye Institute Visual Function Questionnaire-25(NEI-VFQ-25).METHODS:NEI-VFQ-25 was translated into Arabic according to WHO translation guidelines. We enrolled adult consenting patients with bilateral chronic eye diseases who presented to 14 hospitals across Egypt from October to December 2012, and documented their clinical findings. Psychometric properties were then tested using STATA.RESULTS:We recruited 379 patients, whose mean age was(54.5±15)y. Of 46.2% were males, 227 had cataract,31 had glaucoma, 23 had retinal detachment, 37 had diabetic retinopathy, and 61 had miscellaneous visual defects. Non-response rate and the floor and ceiling numbers of the Arabic version(ARB-VFQ-25) were calculated. Internal consistency was high in all subscales(except general health), with Cronbach-α ranging from0.702-0.911. Test-retest reliability was high(intraclass correlation coefficient 0.79).CONCLUSION:RB-VFQ-25 isareliableandvalidtool for assessing visual functions of Arabic speaking patients. However, some questions had high non-response rates and should be substituted by available alternatives. Our results support the importance of including self-reported visual functions as part of routine ophthalmologic examination.展开更多
OBJECTIVE The study aims to translate the Sexual FunctionVaginal Changes Questionnaire （SVQ） into Chinese and to establish its psychometric properties.METHODS A Chinese SVQ was developed by the use of the Brislin mo...OBJECTIVE The study aims to translate the Sexual FunctionVaginal Changes Questionnaire （SVQ） into Chinese and to establish its psychometric properties.METHODS A Chinese SVQ was developed by the use of the Brislin model of translation. The content validity and semantic equivalence were assessed by an expert panel. The translated version of SVQ was administered to 75 Hong Kong Chinese women who were suffered from gynecological cancer to test its psychometric properties.RESULTS The Chinese version of SVQ was compared to the original study for factor analysis. Internal consistency, itemtoscale correlations and test-retest reliability were high. The convergent and divergent validities supported the Chinese SVQ to CONCLUSION We conclude that the Chinese SVQ appears to be a valid, reliable and feasible disease-specific tool for the assessment of sexual function among Chinese patients.展开更多
BACKGROUND Functional gastrointestinal disorders(FGIDs),defined as‘Disorders of Gut-Brain Interaction’,are now considered a global health problem.There is a dearth of concepts and scales to assess the severity of th...BACKGROUND Functional gastrointestinal disorders(FGIDs),defined as‘Disorders of Gut-Brain Interaction’,are now considered a global health problem.There is a dearth of concepts and scales to assess the severity of the different symptoms encountered while dealing with the variety of FGIDs as described in the ROME IV classi-fication.We introduced a novel scoring system with the incorporation of 16 different symptoms called Bacharyya’s Questionnaire Scale and started using it while dealing with children suffering from FGIDs.AIM To verify the usefulness and applicability of this recently developed scale,this study was undertaken with the objectives to establish the validity of this scoring system in assessing the severity of symptoms associated with a specific FGID in children and to determine the scoring system's applicability in assessing the treatment response.METHODS The study included children aged 5 to 18 years diagnosed with any FGID based on ROME IV criteria.They completed the newly developed scale and a Visual Analog Scale at initial diagnosis and after a 2-month treatment period.A control group without FGID participated for comparative baseline purposes.Treatment response was defined as a less than or equal to 50%reduction in the total score,which is statistically significant.RESULTS Results from a comprehensive cohort of 190 cases and 90 controls indicated a female preponderance(57.9%)and prevalent disorders such as functional constipation(28%)and functional abdominal pain,not otherwise specified(21%).The grade of FGID(mild,moderate,severe)experienced by the patients was also derived.Post-treatment,96 children demonstrated symptom improvement.The Spearman rank correlation coefficient for pre(r=0.72,95%CI:0.65-0.77,P value<0.0001)and post(r=0.49,95%CI:0.3-0.64,P value<0.0001)treatment data showed positive results with significant P values.CONCLUSION The novel scoring system shows high comprehensibility and gives an objective view of the symptomatology of FGIDs.The use of this novel score in clinical settings will be helpful to typify the FGIDs and may significantly improve decision-making processes to initiate appropriate treatment.展开更多
Objective To examine the correlation between the health-related quality of life measured by the St.George's Respiratory Questionnaire(SGRQ) and the commonly used physiological measures in lymphangioleiomyomatosis(...Objective To examine the correlation between the health-related quality of life measured by the St.George's Respiratory Questionnaire(SGRQ) and the commonly used physiological measures in lymphangioleiomyomatosis(LAM).Methods This study retrospectively analyzed the SGRQ scores and other measures(the Borg scale of breathlessness at rest,6-minute walking distance,blood oxygen levels,and pulmonary function) of patients diagnosed and confirmed with LAM.Altogether 38 patients between June 2007 and November 2009 were included.Results The mean values of the SGRQ three components(symptoms,activity,and impacts) and total scores in the LAM patients were 46.95±28.90,58.47±25.41,47.89±29.66,and 51.11±26.35,respectively.The SGRQ total or component scores were correlated well with the Borg scale of breathlessness,6-minute walking distance,partial pressure of oxygen in arterial blood,spirometry and diffusion capacity of lung.There were poor correlations between SGRQ score and residual volume or total lung capacity.In our preliminary observation,sirolimus improved the SGRQ total and three component scores and the Borg scale of breathlessness significantly after 101-200 days of treatment(n=6).Conclusions The SGRQ score in LAM is correlated well with physiological measures(Borg scale of breathlessness,6-minute walking distance,blood oxygen levels,and pulmonary function tests).The SGRQ could therefore be recommended in baseline and follow-up evaluation of patients with LAM.Treatment with sirolimus,an inhibitor of mammalian target of rapamycin,may improve the quality of life and patient's perception of breathlessness in LAM.展开更多
Background:The Global Physical Activity Questionnaire(GPAQ)has been used to measure physical activity(PA)and sedentary time in France,but no study has assessed its psychometric properties.This study aimed to compare t...Background:The Global Physical Activity Questionnaire(GPAQ)has been used to measure physical activity(PA)and sedentary time in France,but no study has assessed its psychometric properties.This study aimed to compare the reliability as well as criterion and concurrent validity of the French version of the GPAQ with the French International Physical Activity Questionnaire long form(IPAQ-LF)and use of an accelerometer in a general adult population.Methods:We included 92 participants(students or staff)from the Medicine Campus at the University of Lorraine,Nancy(north-eastern France).The French GPAQ was completed twice,7 days apart,to study test-retest reliability.The IPAQ-LF was used to assess concurrent validity of the GPAQ,and participants wore an accelerometer(ActiGraph GT3X+)for 7 days to study criterion validity.Reliability as well as concurrent and criterion validity of the GPAQ were tested by the intraclass correlation coefficient(ICC),Spearman correlation coefficient for quantitative variables,and Kappa and Phi coefficients for qualitative variables.Both concurrent and criterion validity of GPAQ were assessed by Bland-Altman plots.Results:The GPAQ showed poor to good reliability(ICC=0.37-0.94;Kappa=0.50-0.62)and concurrent validity(Spearman r=0.41-0.86),but only poor criterion validity(Spearman r=-0.22-0.42).Limits of agreement for the GPAQ and accelerometer were wide,with differences between 286.5 min/week and 601.3 min/week.Conclusion:The French version of the GPAQ provides limited but acceptable reliability and validity for the measurement of PA and sedentary time.It may be used for assessing PA and sedentary time in a French adult population.展开更多
目的评估人工角膜移植术后患者的视觉相关生活质量及其影响因素。方法采用横断面研究方法收集2004-01/2019-12月在作者医院接受过单眼MICOF人工角膜或BostonⅠ型人工角膜植入术的127例双眼角膜盲患者人口学资料及临床资料,并采用中文版...目的评估人工角膜移植术后患者的视觉相关生活质量及其影响因素。方法采用横断面研究方法收集2004-01/2019-12月在作者医院接受过单眼MICOF人工角膜或BostonⅠ型人工角膜植入术的127例双眼角膜盲患者人口学资料及临床资料,并采用中文版国家眼科研究所视功能问卷-25项(Chinese national eye institute visual function questionnaire-25,CHI-NEI-VFQ-25)评估患者视觉相关生活质量。采用皮尔逊相关分析和斯皮尔曼相关分析术后手术眼BCVA与视觉相关生活质量的相关性。采用多元逐步线性回归分析视觉相关生活质量的影响因素。结果127例患者中,术后随访(4.31±3.16)年,CHI-NEI-VFQ-25综合得分为(44.18±18.40)分。手术至问卷调查时间间隔<2年的患者远距离活动、心理健康、依赖性、驾驶能力得分和综合评分较手术至问卷调查时间间隔≥2年者更低(P均<0.05);接受米赫(MICOF)人工角膜植入患者眼部疼痛、近距离活动、角色困难得分和综合评分较接受波士顿(Boston)Ⅰ型者更高(P均<0.05)。手术眼的术后最佳矫正视力(best corrected visual acuity,BCVA)与CHI-NEI-VFQ-25综合评分(r=-0.775,P<0.001)及除了眼部疼痛(r=0.139,P=0.120)以外的其他子量表得分均呈负相关(P均<0.05)。术后手术眼BCVA和手术至问卷调查时间间隔<2年对CHI-NEI-VFQ-25综合评分具有负向预测作用(β=-21.546,P<0.001;β=-5.698,P=0.029)。结论双眼角膜盲患者的视觉相关生活质量在接受单眼人工角膜手术后有所改善。术后视觉相关生活质量的主要影响因素是手术眼术后视力,但人工角膜植入手术至问卷调查时间间隔是否<2年也会影响视觉相关生活质量。展开更多
文摘AIM:To develop and test an Arabic version of the National Eye Institute Visual Function Questionnaire-25(NEI-VFQ-25).METHODS:NEI-VFQ-25 was translated into Arabic according to WHO translation guidelines. We enrolled adult consenting patients with bilateral chronic eye diseases who presented to 14 hospitals across Egypt from October to December 2012, and documented their clinical findings. Psychometric properties were then tested using STATA.RESULTS:We recruited 379 patients, whose mean age was(54.5±15)y. Of 46.2% were males, 227 had cataract,31 had glaucoma, 23 had retinal detachment, 37 had diabetic retinopathy, and 61 had miscellaneous visual defects. Non-response rate and the floor and ceiling numbers of the Arabic version(ARB-VFQ-25) were calculated. Internal consistency was high in all subscales(except general health), with Cronbach-α ranging from0.702-0.911. Test-retest reliability was high(intraclass correlation coefficient 0.79).CONCLUSION:RB-VFQ-25 isareliableandvalidtool for assessing visual functions of Arabic speaking patients. However, some questions had high non-response rates and should be substituted by available alternatives. Our results support the importance of including self-reported visual functions as part of routine ophthalmologic examination.
文摘OBJECTIVE The study aims to translate the Sexual FunctionVaginal Changes Questionnaire （SVQ） into Chinese and to establish its psychometric properties.METHODS A Chinese SVQ was developed by the use of the Brislin model of translation. The content validity and semantic equivalence were assessed by an expert panel. The translated version of SVQ was administered to 75 Hong Kong Chinese women who were suffered from gynecological cancer to test its psychometric properties.RESULTS The Chinese version of SVQ was compared to the original study for factor analysis. Internal consistency, itemtoscale correlations and test-retest reliability were high. The convergent and divergent validities supported the Chinese SVQ to CONCLUSION We conclude that the Chinese SVQ appears to be a valid, reliable and feasible disease-specific tool for the assessment of sexual function among Chinese patients.
文摘BACKGROUND Functional gastrointestinal disorders(FGIDs),defined as‘Disorders of Gut-Brain Interaction’,are now considered a global health problem.There is a dearth of concepts and scales to assess the severity of the different symptoms encountered while dealing with the variety of FGIDs as described in the ROME IV classi-fication.We introduced a novel scoring system with the incorporation of 16 different symptoms called Bacharyya’s Questionnaire Scale and started using it while dealing with children suffering from FGIDs.AIM To verify the usefulness and applicability of this recently developed scale,this study was undertaken with the objectives to establish the validity of this scoring system in assessing the severity of symptoms associated with a specific FGID in children and to determine the scoring system's applicability in assessing the treatment response.METHODS The study included children aged 5 to 18 years diagnosed with any FGID based on ROME IV criteria.They completed the newly developed scale and a Visual Analog Scale at initial diagnosis and after a 2-month treatment period.A control group without FGID participated for comparative baseline purposes.Treatment response was defined as a less than or equal to 50%reduction in the total score,which is statistically significant.RESULTS Results from a comprehensive cohort of 190 cases and 90 controls indicated a female preponderance(57.9%)and prevalent disorders such as functional constipation(28%)and functional abdominal pain,not otherwise specified(21%).The grade of FGID(mild,moderate,severe)experienced by the patients was also derived.Post-treatment,96 children demonstrated symptom improvement.The Spearman rank correlation coefficient for pre(r=0.72,95%CI:0.65-0.77,P value<0.0001)and post(r=0.49,95%CI:0.3-0.64,P value<0.0001)treatment data showed positive results with significant P values.CONCLUSION The novel scoring system shows high comprehensibility and gives an objective view of the symptomatology of FGIDs.The use of this novel score in clinical settings will be helpful to typify the FGIDs and may significantly improve decision-making processes to initiate appropriate treatment.
基金Supported by National Basic Research Program of China (973 Program) (2009CB522106)
文摘Objective To examine the correlation between the health-related quality of life measured by the St.George's Respiratory Questionnaire(SGRQ) and the commonly used physiological measures in lymphangioleiomyomatosis(LAM).Methods This study retrospectively analyzed the SGRQ scores and other measures(the Borg scale of breathlessness at rest,6-minute walking distance,blood oxygen levels,and pulmonary function) of patients diagnosed and confirmed with LAM.Altogether 38 patients between June 2007 and November 2009 were included.Results The mean values of the SGRQ three components(symptoms,activity,and impacts) and total scores in the LAM patients were 46.95±28.90,58.47±25.41,47.89±29.66,and 51.11±26.35,respectively.The SGRQ total or component scores were correlated well with the Borg scale of breathlessness,6-minute walking distance,partial pressure of oxygen in arterial blood,spirometry and diffusion capacity of lung.There were poor correlations between SGRQ score and residual volume or total lung capacity.In our preliminary observation,sirolimus improved the SGRQ total and three component scores and the Borg scale of breathlessness significantly after 101-200 days of treatment(n=6).Conclusions The SGRQ score in LAM is correlated well with physiological measures(Borg scale of breathlessness,6-minute walking distance,blood oxygen levels,and pulmonary function tests).The SGRQ could therefore be recommended in baseline and follow-up evaluation of patients with LAM.Treatment with sirolimus,an inhibitor of mammalian target of rapamycin,may improve the quality of life and patient's perception of breathlessness in LAM.
文摘Background:The Global Physical Activity Questionnaire(GPAQ)has been used to measure physical activity(PA)and sedentary time in France,but no study has assessed its psychometric properties.This study aimed to compare the reliability as well as criterion and concurrent validity of the French version of the GPAQ with the French International Physical Activity Questionnaire long form(IPAQ-LF)and use of an accelerometer in a general adult population.Methods:We included 92 participants(students or staff)from the Medicine Campus at the University of Lorraine,Nancy(north-eastern France).The French GPAQ was completed twice,7 days apart,to study test-retest reliability.The IPAQ-LF was used to assess concurrent validity of the GPAQ,and participants wore an accelerometer(ActiGraph GT3X+)for 7 days to study criterion validity.Reliability as well as concurrent and criterion validity of the GPAQ were tested by the intraclass correlation coefficient(ICC),Spearman correlation coefficient for quantitative variables,and Kappa and Phi coefficients for qualitative variables.Both concurrent and criterion validity of GPAQ were assessed by Bland-Altman plots.Results:The GPAQ showed poor to good reliability(ICC=0.37-0.94;Kappa=0.50-0.62)and concurrent validity(Spearman r=0.41-0.86),but only poor criterion validity(Spearman r=-0.22-0.42).Limits of agreement for the GPAQ and accelerometer were wide,with differences between 286.5 min/week and 601.3 min/week.Conclusion:The French version of the GPAQ provides limited but acceptable reliability and validity for the measurement of PA and sedentary time.It may be used for assessing PA and sedentary time in a French adult population.
文摘目的评估人工角膜移植术后患者的视觉相关生活质量及其影响因素。方法采用横断面研究方法收集2004-01/2019-12月在作者医院接受过单眼MICOF人工角膜或BostonⅠ型人工角膜植入术的127例双眼角膜盲患者人口学资料及临床资料,并采用中文版国家眼科研究所视功能问卷-25项(Chinese national eye institute visual function questionnaire-25,CHI-NEI-VFQ-25)评估患者视觉相关生活质量。采用皮尔逊相关分析和斯皮尔曼相关分析术后手术眼BCVA与视觉相关生活质量的相关性。采用多元逐步线性回归分析视觉相关生活质量的影响因素。结果127例患者中,术后随访(4.31±3.16)年,CHI-NEI-VFQ-25综合得分为(44.18±18.40)分。手术至问卷调查时间间隔<2年的患者远距离活动、心理健康、依赖性、驾驶能力得分和综合评分较手术至问卷调查时间间隔≥2年者更低(P均<0.05);接受米赫(MICOF)人工角膜植入患者眼部疼痛、近距离活动、角色困难得分和综合评分较接受波士顿(Boston)Ⅰ型者更高(P均<0.05)。手术眼的术后最佳矫正视力(best corrected visual acuity,BCVA)与CHI-NEI-VFQ-25综合评分(r=-0.775,P<0.001)及除了眼部疼痛(r=0.139,P=0.120)以外的其他子量表得分均呈负相关(P均<0.05)。术后手术眼BCVA和手术至问卷调查时间间隔<2年对CHI-NEI-VFQ-25综合评分具有负向预测作用(β=-21.546,P<0.001;β=-5.698,P=0.029)。结论双眼角膜盲患者的视觉相关生活质量在接受单眼人工角膜手术后有所改善。术后视觉相关生活质量的主要影响因素是手术眼术后视力,但人工角膜植入手术至问卷调查时间间隔是否<2年也会影响视觉相关生活质量。
