期刊文献+
共找到250,259篇文章
< 1 2 250 >
每页显示 20 50 100
Construction of a Self-Directed Learning Model in a Blended Learning Environment
1
作者 Jiafeng Xu Dawei Jia +1 位作者 Jianxin Hao Zhimao Lai 《Journal of Contemporary Educational Research》 2025年第9期316-321,共6页
With blended learning emerging as a mainstream paradigm in higher education,the Document Security Technology course faces persistent challenges,including vague instructional objectives and low learning efficiency.Simu... With blended learning emerging as a mainstream paradigm in higher education,the Document Security Technology course faces persistent challenges,including vague instructional objectives and low learning efficiency.Simultaneously,the profession demands stronger self-directed learning capabilities from practitioners.To address these issues,this study develops a“Five-in-One”self-directed learning model comprising five interrelated dimensions:goal orientation,instructional regulation,cognitive development,technological resources,and process monitoring.The application of this model has significantly improved course evaluation outcomes,enhanced faculty teaching and research capacity,strengthened students’practical and innovative skills,and expanded the course’s reach and social impact.The model thus provides both a theoretical framework and a practical pathway for the reform of similar applied courses. 展开更多
关键词 Blended learning Document security technology Immigration management Police education self-directed learning
在线阅读 下载PDF
Academic self-efficacy and self-directed learning ability among nursing students:The moderating role of learning engagement
2
作者 Huan Ma Jinmei Zou Ying Zhong 《Journal of Psychology in Africa》 2025年第4期481-487,共7页
This study explored the role of learning engagement in the relationship between academic self-efficacy and self-directed learning ability among nursing students.Participants were 328 Chinese nursing students(male=11.3... This study explored the role of learning engagement in the relationship between academic self-efficacy and self-directed learning ability among nursing students.Participants were 328 Chinese nursing students(male=11.3%,female=88.7%;mean age=20.86 years;SD=1.75 years).The participants completed surveys on academic self-efficacy(Academic Self-efficacy Scale),learning engagement(Learning Engagement Scale),and self-directed learning ability(Self-directed Learning Instrument).Hayes regression-based PROCESS macro analysis revealed that learning engagement mediated the relationship between academic self-efficacy and self-directed learning ability.The hierarchical regression analysis showed higher academic self-efficacy to be associated with self-directed learning ability.Additionally learning engagement was associated with higher self-directed learning ability.Based on thesefindings,there is a need for interventions to improve students’self-directed learning ability through increasing their academic self-efficacy and enhancing learning engagement. 展开更多
关键词 academic self-efficacy learning engagement self-directed learning ability nursing students
在线阅读 下载PDF
Research on Compatible Mode of Self-directed Learning and Cooperative Learning in Blended Teaching of Basic English Course
3
作者 李静 《西安翻译学院论坛》 2022年第3期27-31,共5页
In the information age,blended teaching,no matter online or offline,has become the mainstream of college teaching reform.In this teaching model,self-directed learning and cooperative learning are the two main learning... In the information age,blended teaching,no matter online or offline,has become the mainstream of college teaching reform.In this teaching model,self-directed learning and cooperative learning are the two main learning approaches.On the online teaching platform,students mainly learn knowledge-based content by self-directed learning,while practising their language skills by cooperative learning in flipped classroom activities.On one hand,it advocates student-centered strategy so as to improve students autonomous learning ability;on the other hand,teachers serve as a guide to organize the classroom activities;meanwhile,they give timely feedback to students in order to promote students’learning ability.In blended teaching model,this mutually compatible and reinforcing model of self-directed learning and cooperative learning is undoubtedly helpful to improve the teaching efficiency. 展开更多
关键词 self-directed learning cooperative learning blended teaching mutual compatible mode of self-directed learning and cooperative learning
在线阅读 下载PDF
Relationship between self-directed learning readiness, learning attitude, and self-efficacy of nursing undergraduates 被引量:5
4
作者 Li-Na Meng Xiao-Hong Zhang +3 位作者 Meng-Jie Lei Ya-Qian Liu Ting-Ting Liu Chang-De Jin 《Frontiers of Nursing》 CAS 2019年第4期341-348,共8页
Objective: The purposes of this study were to analyze the influencing factors of self-directed learning readiness(SDLR) of nursing undergraduates and explore the impacts of learning attitude and self-efficacy on nursi... Objective: The purposes of this study were to analyze the influencing factors of self-directed learning readiness(SDLR) of nursing undergraduates and explore the impacts of learning attitude and self-efficacy on nursing undergraduates.Methods: A total of 500 nursing undergraduates were investigated in Tianjin, with the Chinese version of SDLR scale, learning attitude questionnaire of nursing college students, academic self-efficacy scale, and the general information questionnaire.Result: The score of SDLR was 149.99±15.73. Multiple stepwise regressions indicated that academic self-efficacy, learning attitude, attitudes to major of nursing, and level of learning difficulties were major influential factors and explained 48.1% of the variance in SDLR of nursing interns.Conclusions: The score of SDLR of nursing undergraduates is not promising. It is imperative to correct students' learning attitude, improve self-efficacy, and adopt appropriate teaching model to improve SDLR. 展开更多
关键词 self-directed learning readiness nursing undergraduates learning attitude academic self-efficacy RELATIONSHIP
暂未订购
Effectiveness of the flipped classroom on the development of self-directed learning in nursing education:a meta-analysis 被引量:3
5
作者 Ya-Qian Liu Yu-Feng Li +6 位作者 Meng-Jie Lei Peng-Xi Liu Julie Theobald Li-Na Meng Ting-Ting Liu Chun-Mei Zhang Chang-De Jin 《Frontiers of Nursing》 CAS 2018年第4期317-329,共13页
Objectives: To examine the best practice evidence of the effectiveness of the flipped classroom(FC) as a burgeoning teaching model on the development of self-directed learning in nursing education.Data sources: The ... Objectives: To examine the best practice evidence of the effectiveness of the flipped classroom(FC) as a burgeoning teaching model on the development of self-directed learning in nursing education.Data sources: The relevant randomized controlled trial(RCT) and non-RCT comparative studies were searched from multiple electronic databases including PubMed, Embase, Web of Science, Cumulative Index to Nursing and Allied Health Literature(CINAHL), Cochrane Central Register of Controlled Trials(CENTRAL), Wanfang Data, China National Knowledge Infrastructure(CNKI), and Chinese Science and Technology Periodical Database(VIP) from inception to June 2017.Review methods: The data were independently assessed and extracted for eligibility by two reviewers. The quality of included studies was assessed by another two reviewers using a standardized form and evaluated by using the Cochrane Collaboration’s risk of bias tool. The self-directed learning scores(continuous outcomes) were analyzed by using the 95% confidence intervals(Cls) with the standard deviation average(SMD) or weighted mean difference(WMD). The heterogeneity was assessed using Cochran’s I;statistic.Results: A total of 12 studies, which encompassed 1440 nursing students(intervention group = 685, control group = 755), were eligible for inclusion in this review. Of 12 included studies, the quality level of one included study was A and of the others was B. The pooled effect size showed that compared with traditional teaching models, the FC could improve nursing students’ selfdirected learning skill, as measured by the Self-Directed Learning Readiness Scale(SDLRS), Self-Directed Learning Readiness Scale for Nursing Education(SDLRSNE), Self-Regulated Learning Scale(SRL), Autonomous Learning Competencies scale(ALC), and Competencies of Autonomous Learning of Nursing Students(CALNS). Overall scores and subgroup analyses with the SRL were all in favor of the FC.Conclusions: The result of this meta-analysis indicated that FCs could improve the effect of self-directed learning in nursing education.Future studies with more RCTs using the same measurement tools are needed to draw more authoritative conclusions. 展开更多
关键词 flipped classroom blended learning reverse teaching self-directed learning self-learning ability SELF-MANAGEMENT nursing education META-ANALYSIS
暂未订购
Self-directed learning readiness and nursing competency among undergraduate nursing students in Fujian province of China 被引量:2
6
作者 Gui-Fang Yang Xiao-Ying Jiang 《International Journal of Nursing Sciences》 2014年第3期255-259,共5页
Aims:We examined the relationship between self-directed learning readiness(SDLR)and nursing competency among undergraduate nursing students.Background:There is little evidence-based data related to the relationship be... Aims:We examined the relationship between self-directed learning readiness(SDLR)and nursing competency among undergraduate nursing students.Background:There is little evidence-based data related to the relationship between selfdirected learning(SDL)and nursing competency.Methods:A descriptive correlational design was used.We conducted convenience sampling of 519 undergraduate nursing students from three universities during their final period of clinical practice.We investigated SDL according to the SDLR scale for nursing education(Chinese translation version),and used the Competency Inventory for Registered Nurses to evaluate nursing competency.Results:The mean SDLR score of the students was 148.55(standard deviation[SD]18.46),indicating intermediate and higher SDLR.The mean score for nursing competency was 142.31(SD30.39),indicating intermediate nursing competence.SDLR had a significant positive and strong relationship with nursing competency.Conclusion:SDLR is a predictor of nursing competency. 展开更多
关键词 BACCALAUREATE COMPETENCY EDUCATION NURSING self-directed learning
暂未订购
Role of academic self-efficacy in the relationship between self-directed learning readiness and problem-solving ability among nursing students
7
作者 Xiao-Hong Zhang Li-Na Meng +4 位作者 Hui-Hui Liu Ru-Zhen Luo Chun-Mei Zhang Pei-Pei Zhang Yan-Hui Liu 《Frontiers of Nursing》 CAS 2018年第1期75-81,共7页
Objective: Problem-solving should be a fundamental component of nursing education because It is a core ability for professional nurses. For more effective learning, nursing students must understand the relationship be... Objective: Problem-solving should be a fundamental component of nursing education because It is a core ability for professional nurses. For more effective learning, nursing students must understand the relationship between self-directed learning readiness and problem-solving ability. The aim of this study was to investigate the relationships among self-directed learning readiness, problemsolving ability, and academic self-efficacy among undergraduate nursing students.Methods: From November to December 2016, research was conducted among 500 nursing undergraduate students in Tianjin, China,using a self-directed learning readiness scale, an academic self-efficacy scale, a questionnaire related to problem-solving, and selfdesigned demographics. The response rate was 85.8%.Results: For Chinese nursing students, self-directed learning readiness and academic self-efficacy reached a medium-to-high level,while problem-solving abilities were at a low level. There were significant positive correlations among the students' self-directed learning readiness, academic self-efficacy, and problem-solving ability. Furthermore, academic self-efficacy demonstrated a mediating effect on the relationship between the students' self-directed learning readiness and problem-solving ability.Conclusions: To enhance students' problem-solving ability, nursing educators should pay more attention to the positive impact of self-directed learning readiness and self-efficacy in nursing students' education. 展开更多
关键词 self-directed learning readiness problem-solving ability academic self-efficacy nursing undergraduates nursing students cross-sectional survey
暂未订购
Self-directed learning readiness and social problem solving of nursing students in Macao
8
作者 Yuan Haobin 《护理学杂志》 CSCD 2016年第1期1-7,共7页
Objective The aims of this study were to describe nursing students′self-directed learning readiness and social problem solving and test their correlations in Macao.Methods This descriptive cross-sectional study was c... Objective The aims of this study were to describe nursing students′self-directed learning readiness and social problem solving and test their correlations in Macao.Methods This descriptive cross-sectional study was conducted on 140baccalaureate nursing students.A stratified random sampling was performed.The Self-directed Learning Readiness(SDLR)Scale and Chinese Social Problem-Solving Inventory-Revised(C-SPSI-R)were used.Results The response rate was 79.3%.Students possessed readiness for self-directed learning(mean 149.09±12.53,51.4%at high level,48.6%at low level).Regarding to social problem solving,the mean scores of each subscale were 9.35±3.25(Rational Problem Solving,RPS),10.26±3.23(Positive Problem Orientation,PPO),8.14±4.06(Negative Problem Orientation,NPO),5.67±4.44(Avoidance Style,AS),and 4.84±3.03(Impulsivity/Carelessness Style,ICS).SDLR was positively related to RPS and PPO,but was negatively related to AS.Conclusion Half of students possessed stronger readiness for self-directed learning.Students had a belief in the ability to solve problems,and adopted relevant strategies in solving problems.However,students still had negative and dysfunctional orientation and defective attempts in solving problems.Self-directed learning was positively related to positive and constructive orientation,but was negatively related to defective problem-solving pattern.Nurse educators should create educational climates for promoting student confidence and mutual responsibility for learning and their thinking process for problem solving. 展开更多
关键词 nursing student self-directed learning READINESS social problem solving MACAO
在线阅读 下载PDF
The effect of self-observation on the self-directed learning ability of nursing students: An experimental study 被引量:1
9
作者 Dong-Hee Kim 《Open Journal of Nursing》 2013年第8期517-523,共7页
Background: Patients expect nurses to be both technically competent and psychosocially skilled. Enhancing the quality of patient care and patient safety in healthcare settings has increased, resulting in limited oppor... Background: Patients expect nurses to be both technically competent and psychosocially skilled. Enhancing the quality of patient care and patient safety in healthcare settings has increased, resulting in limited opportunities for students to practice clinical skills in healthcare settings. Achieving competence in these skills is viewed as an essential task to be completed during the school curriculum. Objective: The purpose of this study was to evaluate the use of self-observation through cellular recordings as an adjunct to the clinical skills teaching of a blood sugar test to undergraduate nursing. Design: The research design consisted of pre- and post-test consecutive experimental design through a control group. Settings: This study targeted nursing students enrolled in baccalaureate programs running in Korea. Participant: The participants were 64 students including 34 for the experimental group and 30 for the control group. Methods: Those in the control group received standard teaching methods using lectures and skills classes and facilitated the use of self-study methods. Those in the experimental group received standard teaching using lectures and skills classes and facilitated use of cell phone recorded self-observation. The self-confidence of practicing a blood sugar test, satisfaction with the learning method, self-study participation, level of interest in nursing practice, and self-directed learning ability were measured using questionnaires. Results: Significant between-groups differences were detected in self-confidence of practicing a blood sugar test (t = 2.067, p = 0.043), satisfaction with the learning method (t = 2.818, p = 0.044), self-study participation (χ2 = 7.635, p = 0.022), and average self-directed learning ability (t = 3.202, p = 0.002). Conclusions: Self-observation through cellular phone recordings is an effective learning method as an adjunct to teach clinical skills. 展开更多
关键词 Cellular PHONE ANIMATION SELF-CONFIDENCE SATISFACTION learning NURSING SKILL
暂未订购
Impact of self-directed learning readiness and learning attitude on problem-solving ability among Chinese undergraduate nursing students
10
作者 Ru-Zhen Luo Xiao-Hong Zhang +1 位作者 Chun-Mei Zhang Yan-Hui Liu 《Frontiers of Nursing》 CAS 2019年第2期143-150,共8页
Objective: To explore the effects of self-directed learning readiness and learning attitude on problem-solving ability among Chinese undergraduate nursing students. Methods: A convenience sampling of 460 undergraduate... Objective: To explore the effects of self-directed learning readiness and learning attitude on problem-solving ability among Chinese undergraduate nursing students. Methods: A convenience sampling of 460 undergraduate nursing students was surveyed in Tianjin, China. Students who participated in the study completed a questionnaire that included social demographic questionnaire, Self-directed Learning Readiness Scale, Attitude to Learning Scale, and Social Problem-Solving Inventory. Pearson’s correlation analysis was performed to test the correlations among problem-solving ability, self-directed learning readiness, and learning attitude. Hierarchical linear regression analyses were performed to explore the mediating role of learning attitude. Results: The results showed that learning attitude (r=0.338, P<0.01) and self-directed learning readiness (r=0.493, P<0.01) were positively correlated with problem-solving ability. Learning attitude played a partial intermediary role between self-directed learning readiness and problem-solving ability (F=74.227, P<0.01). Conclusions: It is concluded that nursing educators should pay attention on students’ individual differences and take proper actions to inspire students’ self-directed learning readiness and learning attitude. 展开更多
关键词 UNDERGRADUATE NURSING students self-directed learning READINESS learning ATTITUDE problem-solving ABILITY China
暂未订购
Nursing Students’ Readiness for Self-Directed Learning and Its Effect on Learning Outcome in South-West Nigeria
11
作者 Guobadia Pauline Ojekou Funmilayo A. Okanlawon 《Open Journal of Nursing》 2019年第6期586-601,共16页
Self-directed learning (SDL) uses diverse learning resources to solve identified problems in learning. Nursing is a lifelong learning profession and SDL is a valuable skill to remain relevant and productive profession... Self-directed learning (SDL) uses diverse learning resources to solve identified problems in learning. Nursing is a lifelong learning profession and SDL is a valuable skill to remain relevant and productive professionals. Nursing students are expected to embrace SDL and develop these skills. However, there has been no evidence of this innovative process in South-West Nigeria. This study seeks to evaluate nursing students’ readiness for SDL and its effect on learning outcome. This quasi-experimental study purposively utilized 229 nursing students as participants. Baseline (P1) data was collected using Gugliemino’s SDL readiness scale (SDLRS) and a validated-structured questionnaire. Participants had a pre-test to assess knowledge at P1 followed by 6 weeks interaction using SDL on selected topics in Medical-surgical nursing and the same test at post-intervention (P2). Using a 50-point scale, knowledge was categorized as good ≥ 25 and poor < 25 and SDLRS on a 290-point scale was categorized as below average 5 - 201, average 202 - 226 and above average 227 - 290. Descriptive statistics, Chi-square test, t-test and linear regression analysis were used for analysis at p = 0.05. Nursing students’ SDLRS was average;mean = 203 ± 23.0. A significant difference exists between nursing students with good knowledge at P1 and P2. At P1, 39.2% had good knowledge, mean = 22.2 ± 6.3, and 90.1% at P2, mean = 30.6 ± 5.4, p < 0.05 also a significant relationship exist between SDLR and learning outcome at P2;p < 0.05. With the nursing students’ average SDL readiness level having a significant effect on learning outcome. Nursing training institutions should provide necessary resources to embrace SDL as a main-line teaching method to ensure competent life-long professionals. 展开更多
关键词 Effects self-directed learning READINESS Resources learning OUTCOME NURSING Students
暂未订购
Research-Led and Project-Based Learning:A Case Study on Self-Directed Pedagogical Approach for Modern Higher Architecture Education
12
作者 Fangde Ren Qichao Ban +1 位作者 Huifei Deng Kai Wu 《教育技术与创新》 2025年第4期59-72,共14页
Contemporary higher education prioritizes cultivating students’key competencies and comprehensive problem-solving abilities,specifically fostering innovation,goal orientation,and initiative.This study investigates a ... Contemporary higher education prioritizes cultivating students’key competencies and comprehensive problem-solving abilities,specifically fostering innovation,goal orientation,and initiative.This study investigates a pedagogical framework that synergizes Research-Led Learning(RLL)and Project-Based Learning(PBL)to establish an open,exploratory learning environment.Employing a case study methodology,the research tracked architecture students engaging in a structured PBL process involving rigorous research activities—ranging from theoretical analysis to field investigations—to develop evidence-based design solutions.Evaluations from both student and faculty perspectives assessed the pedagogical effectiveness regarding learning outcomes and competency development.The findings indicate that this methodology effectively bridges the gap between research and practice,significantly bolstering students’capacity to address authentic challenges and propelling self-directed learning in architectural education. 展开更多
关键词 research-led learning(RLL) project-based learning(PBL) selfdirected learning pedagogical approach modern higher architectural education marine building
在线阅读 下载PDF
Psychological Capital and Self-directed Learning Abilities of Graduate School Candidates
13
作者 Wang Xin 《Education and Teaching Research》 2024年第2期1-3,共3页
In China,about 4.74 million Chinese have signed up for the 2023 national exam for postgraduate enrollment.More and more students will pursue a graduate school education.It’s important to note that the self-directed l... In China,about 4.74 million Chinese have signed up for the 2023 national exam for postgraduate enrollment.More and more students will pursue a graduate school education.It’s important to note that the self-directed learning abilities of the students is crucial in the postgraduate entrance exam.Therefore,the study seeks to identify the level of the self-directed learning abilities and psychological capital of the postgraduate school candidates to identify whether there is a significant correlation between the candidates’self-directed learning abilities and psychological capital. 展开更多
关键词 Psychological Capital self-directed learning Ability National Graduate School Entrance Exam
在线阅读 下载PDF
Psychological Capital and Self-directed Learning Abilities of Graduate School Candidates
14
作者 Wang Xin 《Education and Teaching Research》 2024年第3期1-3,共3页
In China,about 4.74 million Chinese have signed up for the 2023 national exam for postgraduate enrollment.More and more students will pursue a graduate school education.It’s important to note that the self-directed l... In China,about 4.74 million Chinese have signed up for the 2023 national exam for postgraduate enrollment.More and more students will pursue a graduate school education.It’s important to note that the self-directed learning abilities of the students is crucial in the postgraduate entrance exam.Therefore,the study seeks to identify the level of the self-directed learning abilities and psychological capital of the postgraduate school candidates to identify whether there is a significant correlation between the candidates’self-directed learning abilities and psychological capital. 展开更多
关键词 Psychological Capital self-directed learning Ability National Graduate School Entrance Exam
在线阅读 下载PDF
Predicting lymph node metastasis in colorectal cancer using caselevel multiple instance learning
15
作者 Ling-Feng Zou Xuan-Bing Wang +4 位作者 Jing-Wen Li Xin Ouyang Yi-Ying Luo Yan Luo Cheng-Long Wang 《World Journal of Gastroenterology》 2026年第1期110-125,共16页
BACKGROUND The accurate prediction of lymph node metastasis(LNM)is crucial for managing locally advanced(T3/T4)colorectal cancer(CRC).However,both traditional histopathology and standard slide-level deep learning ofte... BACKGROUND The accurate prediction of lymph node metastasis(LNM)is crucial for managing locally advanced(T3/T4)colorectal cancer(CRC).However,both traditional histopathology and standard slide-level deep learning often fail to capture the sparse and diagnostically critical features of metastatic potential.AIM To develop and validate a case-level multiple-instance learning(MIL)framework mimicking a pathologist's comprehensive review and improve T3/T4 CRC LNM prediction.METHODS The whole-slide images of 130 patients with T3/T4 CRC were retrospectively collected.A case-level MIL framework utilising the CONCH v1.5 and UNI2-h deep learning models was trained on features from all haematoxylin and eosinstained primary tumour slides for each patient.These pathological features were subsequently integrated with clinical data,and model performance was evaluated using the area under the curve(AUC).RESULTS The case-level framework demonstrated superior LNM prediction over slide-level training,with the CONCH v1.5 model achieving a mean AUC(±SD)of 0.899±0.033 vs 0.814±0.083,respectively.Integrating pathology features with clinical data further enhanced performance,yielding a top model with a mean AUC of 0.904±0.047,in sharp contrast to a clinical-only model(mean AUC 0.584±0.084).Crucially,a pathologist’s review confirmed that the model-identified high-attention regions correspond to known high-risk histopathological features.CONCLUSION A case-level MIL framework provides a superior approach for predicting LNM in advanced CRC.This method shows promise for risk stratification and therapy decisions,requiring further validation. 展开更多
关键词 Colorectal cancer Lymph node metastasis Deep learning Multiple instance learning HISTOPATHOLOGY
暂未订购
RankXLAN:An explainable ensemble-based machine learning framework for biomarker detection,therapeutic target identification,and classification using transcriptomic and epigenomic stomach cancer data
16
作者 Kasmika Borah Himanish Shekhar Das +1 位作者 Mudassir Khan Saurav Mallik 《Medical Data Mining》 2026年第1期13-31,共19页
Background:Stomach cancer(SC)is one of the most lethal malignancies worldwide due to late-stage diagnosis and limited treatment.The transcriptomic,epigenomic,and proteomic,etc.,omics datasets generated by high-through... Background:Stomach cancer(SC)is one of the most lethal malignancies worldwide due to late-stage diagnosis and limited treatment.The transcriptomic,epigenomic,and proteomic,etc.,omics datasets generated by high-throughput sequencing technology have become prominent in biomedical research,and they reveal molecular aspects of cancer diagnosis and therapy.Despite the development of advanced sequencing technology,the presence of high-dimensionality in multi-omics data makes it challenging to interpret the data.Methods:In this study,we introduce RankXLAN,an explainable ensemble-based multi-omics framework that integrates feature selection(FS),ensemble learning,bioinformatics,and in-silico validation for robust biomarker detection,potential therapeutic drug-repurposing candidates’identification,and classification of SC.To enhance the interpretability of the model,we incorporated explainable artificial intelligence(SHapley Additive exPlanations analysis),as well as accuracy,precision,F1-score,recall,cross-validation,specificity,likelihood ratio(LR)+,LR−,and Youden index results.Results:The experimental results showed that the top four FS algorithms achieved improved results when applied to the ensemble learning classification model.The proposed ensemble model produced an area under the curve(AUC)score of 0.994 for gene expression,0.97 for methylation,and 0.96 for miRNA expression data.Through the integration of bioinformatics and ML approach of the transcriptomic and epigenomic multi-omics dataset,we identified potential marker genes,namely,UBE2D2,HPCAL4,IGHA1,DPT,and FN3K.In-silico molecular docking revealed a strong binding affinity between ANKRD13C and the FDA-approved drug Everolimus(binding affinity−10.1 kcal/mol),identifying ANKRD13C as a potential therapeutic drug-repurposing target for SC.Conclusion:The proposed framework RankXLAN outperforms other existing frameworks for serum biomarker identification,therapeutic target identification,and SC classification with multi-omics datasets. 展开更多
关键词 stomach cancer BIOINFORMATICS ensemble learning classifier BIOMARKER targets
在线阅读 下载PDF
Deep Learning-Assisted Organogel Pressure Sensor for Alphabet Recognition and Bio-Mechanical Motion Monitoring
17
作者 Kusum Sharma Kousik Bhunia +5 位作者 Subhajit Chatterjee Muthukumar Perumalsamy Anandhan Ayyappan Saj Theophilus Bhatti Yung‑Cheol Byun Sang-Jae Kim 《Nano-Micro Letters》 2026年第2期644-663,共20页
Wearable sensors integrated with deep learning techniques have the potential to revolutionize seamless human-machine interfaces for real-time health monitoring,clinical diagnosis,and robotic applications.Nevertheless,... Wearable sensors integrated with deep learning techniques have the potential to revolutionize seamless human-machine interfaces for real-time health monitoring,clinical diagnosis,and robotic applications.Nevertheless,it remains a critical challenge to simultaneously achieve desirable mechanical and electrical performance along with biocompatibility,adhesion,self-healing,and environmental robustness with excellent sensing metrics.Herein,we report a multifunctional,anti-freezing,selfadhesive,and self-healable organogel pressure sensor composed of cobalt nanoparticle encapsulated nitrogen-doped carbon nanotubes(CoN CNT)embedded in a polyvinyl alcohol-gelatin(PVA/GLE)matrix.Fabricated using a binary solvent system of water and ethylene glycol(EG),the CoN CNT/PVA/GLE organogel exhibits excellent flexibility,biocompatibility,and temperature tolerance with remarkable environmental stability.Electrochemical impedance spectroscopy confirms near-stable performance across a broad humidity range(40%-95%RH).Freeze-tolerant conductivity under sub-zero conditions(-20℃)is attributed to the synergistic role of CoN CNT and EG,preserving mobility and network integrity.The Co N CNT/PVA/GLE organogel sensor exhibits high sensitivity of 5.75 k Pa^(-1)in the detection range from 0 to 20 k Pa,ideal for subtle biomechanical motion detection.A smart human-machine interface for English letter recognition using deep learning achieved 98%accuracy.The organogel sensor utility was extended to detect human gestures like finger bending,wrist motion,and throat vibration during speech. 展开更多
关键词 Wearable ORGANOGEL Deep learning Pressure sensor Bio-mechanical motion
在线阅读 下载PDF
上一页 1 2 250 下一页 到第
使用帮助 返回顶部